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Yamamoto Ken-ichi  山本 健一

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Yamamoto Kenichi  山本 健一

YAMAMOTO Kenichi  山本 健一

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Researcher Number 00711798
Other IDs
Affiliation (Current) 2025: 岡山大学, 医歯薬学域, 助教
Affiliation (based on the past Project Information) *help 2021 – 2024: 岡山大学, 医歯薬学域, 助教
2017 – 2020: 岡山大学, 医歯薬学総合研究科, 助教
2014 – 2015: 佐賀大学, 医学部, 研究員
2013: 佐賀大学, 医学部, 非常勤博士研究員
Review Section/Research Field
Principal Investigator
Basic Section 53050:Dermatology-related / Basic Section 50010:Tumor biology-related
Except Principal Investigator
Basic Section 50010:Tumor biology-related / Basic Section 56070:Plastic and reconstructive surgery-related / Tumor biology / Collagenous pathology/Allergology
Keywords
Principal Investigator
TPL2 / MCAM / 乾癬 / アトピー性皮膚炎 / S100A8/A9 / がん感化型線維芽細胞 / COX2 / PEG2 / PGE2 / p70S6K … More / 線維芽細胞 / 膵臓がん / 線維化 / 間質線維芽細胞 / RAGE / S100A11 … More
Except Principal Investigator
転移 / S100A8/A9 / がん / 受容体 / 阻害作用 / HRG / 変性コラーゲン / 再生医療 / 再上皮化 / 難治性潰瘍 / β3インテグリン遺伝子導入ヒト表皮角化細胞 / 炎症 / がん転移抑制タンパク質 / S100A8/A9中和抗 / H R G / 脳転移 / 中和抗体 / 遺伝子導入ヒト表皮角化細胞 / αvβ3インテグリン / 細胞治療 / 再上皮化促進 / β3インテグリン / α5インテグリン / フィブロネクチン / 正常ヒト表皮角化細胞 / フィブリンゲル / β3遺伝子導入ヒト表皮角化細胞 / S100A8/A9受容体 / 気管支喘息 / ペリオスチン / 上皮細胞 / 結膜炎 / サイトカイン / アレルギー性結膜炎 / アトピー性皮膚炎 / アレルギー Less
  • Research Projects

    (8 results)
  • Research Products

    (86 results)
  • Co-Researchers

    (44 People)
  •  S100A8/A9-向転移とHRG-抗転移の細胞間・分子間クロストークの解明

    • Principal Investigator
      阪口 政清
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Okayama University
  •  難治性潰瘍での変性コラーゲンの局在証明、再上皮化遅延の病態解明とその治療法開発

    • Principal Investigator
      久保 美代子
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56070:Plastic and reconstructive surgery-related
    • Research Institution
      Okayama University
  •  乾癬、アトピー性皮膚炎におけるMCAMの意義探求とその制御製剤による病態制御Principal Investigator

    • Principal Investigator
      山本 健一
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53050:Dermatology-related
    • Research Institution
      Okayama University
  •  β3インテグリン遺伝子導入ヒト表皮角化細胞を用いた難治性潰瘍に対する新規再生医療

    • Principal Investigator
      久保 美代子
    • Project Period (FY)
      2020 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56070:Plastic and reconstructive surgery-related
    • Research Institution
      Okayama University
  •  Identification of HRG that is highly inhibitory to S100A8/A9-mediated organ tropic cancer metastasis

    • Principal Investigator
      Sakaguchi Masakiyo
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Okayama University
  •  Upregulation of mobility in pancreastic cancer cells by secreted S100A11 through activation of surrounding fibroblasts.Principal Investigator

    • Principal Investigator
      Yamamoto Kenichi
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Okayama University
  •  Mechanistic analysis of an unidentified downstream signals of S100A8/A9 receptors that play a crucial role in acquisition of metastatic force and formation of cancer microenvironment.

    • Principal Investigator
      Sakaguchi Masakiyo
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Tumor biology
    • Research Institution
      Okayama University
  •  Clarification of the mechanism of the chronicity of allergic diseases and establishment of the thrapeutic strategy against it

    • Principal Investigator
      Izuhara Kenji
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Collagenous pathology/Allergology
    • Research Institution
      Saga University

All 2024 2023 2022 2021 2020 2019 2018 2017 2015 2014

All Journal Article Presentation Book Patent

  • [Book] 月刊「細胞」第49巻第3号2017

    • Author(s)
      阪口政清、木下理恵、村田 等、山本健一、許 南浩、日比野利彦
    • Total Pages
      52
    • Publisher
      ニューサイエンス社
    • Data Source
      KAKENHI-PROJECT-17H03577
  • [Book] 月刊「臨床免疫、アレルギー科」第67巻第6号2017

    • Author(s)
      阪口政清、 山本真実, 宮井雅史, 木下理恵, 村田 等, 山本健一, 森実 真, 岩月啓氏, 許 南浩, 坪井良治, 日比野 利彦
    • Total Pages
      10
    • Publisher
      科学評論社
    • Data Source
      KAKENHI-PROJECT-17H03577
  • [Book] 月刊「細胞」第49巻第7号2017

    • Author(s)
      阪口政清、木下理恵、村田 等、山本健一、許 南浩、日比野利彦
    • Total Pages
      52
    • Publisher
      ニューサイエンス社
    • Data Source
      KAKENHI-PROJECT-17H03577
  • [Book] Metabolism of Human Diseases2014

    • Author(s)
      Izuhara K, Suzuki S, Arima K, Ohta S, Inamitsu M, Yamamoto K
    • Total Pages
      416
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-25293224
  • [Journal Article] Lysyl oxidase-like 4 promotes the invasiveness of triple-negative breast cancer cells by orchestrating the invasive machinery formed by annexin A2 and S100A11 on the cell surface2024

    • Author(s)
      Takahashi Tetta、Tomonobu Nahoko、Kinoshita Rie、Yamamoto Ken-ichi、Murata Hitoshi、Komalasari Ni Luh Gede Yoni、...、Honjo Tomoko、Sakaguchi Yoshihiko、Yamauchi Akira、Kuribayashi Futoshi、Kondo Eisaku、Inoue Yusuke、Futami Junichiro、Toyooka Shinichi、Zamami Yoshito、Sakaguchi Masakiyo
    • Journal Title

      Frontiers in Oncology

      Volume: 14 Pages: 1371342-1371342

    • DOI

      10.3389/fonc.2024.1371342

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K14595, KAKENHI-PROJECT-22K07074, KAKENHI-PROJECT-23K06717, KAKENHI-PROJECT-22K20793, KAKENHI-PROJECT-22H04923, KAKENHI-PROJECT-23K27439
  • [Journal Article] Correction to: Periostin secreted by cancer-associated fibroblasts promotes cancer progression and drug resistance in non-small cell lung cancer2023

    • Author(s)
      Takatsu Fumiaki、Suzawa Ken、Tomida Shuta、Thu Yin Min、Sakaguchi Masakiyo、Toji Tomohiro、Ohki Masayoshi、Tsudaka Shimpei、Date Keiichi、Matsuda Naoki、Iwata Kazuma、Zhu Yidan、Nakata Kentaro、Shien Kazuhiko、Yamamoto Hiromasa、Nakayama Akiko、Okazaki Mikio、Sugimoto Seiichiro、Toyooka Shinichi
    • Journal Title

      Journal of Molecular Medicine

      Volume: 102 Issue: 1 Pages: 147-147

    • DOI

      10.1007/s00109-023-02408-2

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K24421, KAKENHI-PROJECT-23K27439
  • [Journal Article] LOXL1 and LOXL4 are novel target genes of the Zn2+-bound form of ZEB1 and play a crucial role in the acceleration of invasive events in triple-negative breast cancer cells2023

    • Author(s)
      Daisuke Hirabayashi, Ken-ichi Yamamoto, Akihiro Maruyama, Nahoko Tomonobu, Rie Kinoshita, Youyi Chen, Ni Luh Gede Yoni Komalasari, Hitoshi Murata, Yuma Gohara, Fan Jiang, Jin Zhou, I Made Winarsa Ruma, I Wayan Sumardika, Akira Yamauchi, Futoshi Kuribayashi, Shinichi Toyooka, Yusuke Inoue, Masakiyo Sakaguchi
    • Journal Title

      Frontiers in Oncology

      Volume: 13 Pages: 1142886-1142886

    • DOI

      10.3389/fonc.2023.1142886

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K20793, KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-22K06884, KAKENHI-PROJECT-23K06478, KAKENHI-PROJECT-22H04923
  • [Journal Article] Phosphorylated SARM1 is involved in the pathological process of rotenone-induced neurodegeneration2023

    • Author(s)
      Murata Hitoshi、Phoo May Tha Zin、Ochi Toshiki、Tomonobu Nahoko、Yamamoto Ken-ichi、Kinoshita Rie、Miyazaki Ikuko、Nishibori Masahiro、Asanuma Masato、Sakaguchi Masakiyo
    • Journal Title

      The Journal of Biochemistry

      Volume: 174 Issue: 6 Pages: 533-548

    • DOI

      10.1093/jb/mvad068

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K14595, KAKENHI-PROJECT-22K06884, KAKENHI-PROJECT-23K06717, KAKENHI-PROJECT-23K06928, KAKENHI-PROJECT-21K07415, KAKENHI-PROJECT-22K20793, KAKENHI-PROJECT-23K27439
  • [Journal Article] Periostin secreted by cancer-associated fibroblasts promotes cancer progression and drug resistance in non-small cell lung cancer2023

    • Author(s)
      Takatsu F, Suzawa K, Tomida S, Thu YM, Sakaguchi M, Shien K, Yamamoto H, Nakayama A, Okazaki M, Sugimoto S, Toyooka S
    • Journal Title

      Journal of molecular medicine (Berlin, Germany)

      Volume: 101 Issue: 12 Pages: 1603-1614

    • DOI

      10.1007/s00109-023-02384-7

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22H04923, KAKENHI-PROJECT-23K27439, KAKENHI-PROJECT-23K27688
  • [Journal Article] Novel extracellular role of REIC/Dkk-3 protein in PD-L1 regulation in cancer cells.2023

    • Author(s)
      Yuma Gohara, Nahoko Tomonobu, Rie Kinoshita, Junichiro Futami, Lena Audebert, Youyi Chen, Ni Luh Gede Yoni Komalasari, Fan Jiang, Chikako Yoshizawa, Hitoshi Murata, Ken-Ichi Yamamoto, Masami Watanabe, Hiromi Kumon, Masakiyo Sakaguchi
    • Journal Title

      Journal of molecular medicine (Berlin, Germany)

      Volume: 101 Issue: 4 Pages: 431-447

    • DOI

      10.1007/s00109-023-02292-w

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K20793, KAKENHI-PROJECT-20K07636, KAKENHI-PROJECT-23K14595, KAKENHI-PROJECT-22K06884, KAKENHI-PROJECT-22H04923, KAKENHI-PROJECT-19H01064, KAKENHI-PROJECT-23K27439
  • [Journal Article] STAT1/3 signaling suppresses axon degeneration and neuronal cell death through regulation of NAD+-biosynthetic and consuming enzymes2023

    • Author(s)
      Murata Hitoshi、Yasui Yu、Oiso Kazuma、Ochi Toshiki、Tomonobu Nahoko、Yamamoto Ken-ichi、Kinoshita Rie、Sakaguchi Masakiyo
    • Journal Title

      Cellular Signalling

      Volume: 108 Pages: 110717-110717

    • DOI

      10.1016/j.cellsig.2023.110717

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K14595, KAKENHI-PROJECT-23K06717, KAKENHI-PROJECT-22K20793, KAKENHI-PROJECT-22H04923, KAKENHI-PROJECT-23K27439
  • [Journal Article] Lysyl oxidase-like 4 exerts an atypical role in breast cancer progression that is dependent on the enzymatic activity that targets the cell-surface annexin A22023

    • Author(s)
      Sakaguchi, M., Komalasari, N. L. G. Y., Tomonobu, N., Kinoshita, R., Chen, Y., Sakaguchi, Y., Gohara, Y., Jiang, F., Yamamoto, K., Murata, H., Ruma, I. M. W., Sumardika, I. W., Zhou, J., Yamauchi, A., Kuribayashi, F., Inoue, Y., Toyooka, S.
    • Journal Title

      Front. Oncol.

      Volume: 13 Pages: 1142907-1142907

    • DOI

      10.3389/fonc.2023.1142907

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K07074, KAKENHI-PROJECT-23K14595, KAKENHI-PROJECT-22K06884, KAKENHI-PROJECT-23K06717, KAKENHI-PROJECT-22K20793, KAKENHI-PROJECT-23K27439
  • [Journal Article] Exosomal Wnt7a from a low metastatic subclone promotes lung metastasis of a highly metastatic subclone in the murine 4t1 breast cancer2022

    • Author(s)
      Li C, Yoshimura T, Tian M, Wang Y, Kondo T, Yamamoto KI, Fujisawa M, Ohara T, Sakaguchi M, Matsukawa A
    • Journal Title

      Breast Cancer Res

      Volume: 24 Issue: 1 Pages: 60-60

    • DOI

      10.1186/s13058-022-01557-5

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K19562, KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-22H04923
  • [Journal Article] Functional Blockage of S100A8/A9 Ameliorates Ischemia Reperfusion Injury in the Lung2022

    • Author(s)
      Nakata Kentaro、Okazaki Mikio、Sakaue Tomohisa、Kinoshita Rie、Komoda Yuhei、Shimizu Dai、Yamamoto Haruchika、Tanaka Shin、Suzawa Ken、Shien Kazuhiko、Miyoshi Kentaroh、Yamamoto Hiromasa、Ohara Toshiaki、Sugimoto Seiichiro、Yamane Masaomi、Matsukawa Akihiro、Sakaguchi Masakiyo、Toyooka Shinichi
    • Journal Title

      Bioengineering

      Volume: 9 Issue: 11 Pages: 673-673

    • DOI

      10.3390/bioengineering9110673

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K09164, KAKENHI-PROJECT-20KK0203, KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-20K07636, KAKENHI-PROJECT-22H04923
  • [Journal Article] Presence of Microplastics in Four Types of Shellfish Purchased at Fish Markets in Okayama City, Japan2021

    • Author(s)
      Yamamoto Ken-ichi、Oshiki Toshiyuki、Kagawa Hiroko、Namba Masayoshi、Sakaguchi Masakiyo
    • Journal Title

      Acta Medica Okayama

      Volume: 75 Issue: 3 Pages: 381-384

    • DOI

      10.18926/AMO/62234

    • NAID

      120007089831

    • URL

      https://ousar.lib.okayama-u.ac.jp/62234

    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-16H06277
  • [Journal Article] Oncogenic potential of human pluripotent stem cell‐derived lung organoids with <scp>HER2</scp> overexpression2021

    • Author(s)
      Miura Akihiro、Yamada Daisuke、Nakamura Masahiro、Tomida Shuta、Shimizu Dai、Jiang Yan、Takao Tomoka、Yamamoto Hiromasa、Suzawa Ken、Shien Kazuhiko、Yamane Masaomi、Sakaguchi Masakiyo、Toyooka Shinichi、Takarada Takeshi
    • Journal Title

      International Journal of Cancer

      Volume: 149 Issue: 8 Pages: 1593-1604

    • DOI

      10.1002/ijc.33713

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-20H03771, KAKENHI-PROJECT-21K07192, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-23K21368
  • [Journal Article] Cytotoxic Effects of Alcohol Extracts from a Plastic Wrap (Polyvinylidene Chloride) on Human Cultured Liver Cells and Mouse Primary Cultured Liver Cells2020

    • Author(s)
      Yamamoto KI, Kagawa H, Arimoto S, Tan XW, Yasui K, Oshiki T, Sakaguchi M.
    • Journal Title

      Acta Medica Okayama

      Volume: 74 Issue: 4 Pages: 327-334

    • DOI

      10.18926/AMO/60371

    • NAID

      120006880210

    • URL

      https://ousar.lib.okayama-u.ac.jp/60371

    • Language
      English
    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-16H06277
  • [Journal Article] Antitumor Effects of Pan-RAF Inhibitor LY3009120 Against Lung Cancer Cells Harboring Oncogenic BRAF Mutation2020

    • Author(s)
      MIYAUCHI SHUNSAKU、SHIEN KAZUHIKO、TAKEDA TATSUAKI、ARAKI KOTA、NAKATA KENTARO、MIURA AKIHIRO、TAKAHASHI YUTA、KURIHARA EISUKE、OGOSHI YUSUKE、NAMBA KEI、SUZAWA KEN、YAMAMOTO HIROMASA、OKAZAKI MIKIO、SOH JUNICHI、TOMIDA SHUTA、YAMANE MASAOMI、SAKAGUCHI MASAKIYO、TOYOOKA SHINICHI
    • Journal Title

      Anticancer Research

      Volume: 40 Issue: 5 Pages: 2667-2673

    • DOI

      10.21873/anticanres.14237

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-20H03771, KAKENHI-PROJECT-16H06277
  • [Journal Article] The heterodimer S100A8/A9 is a potent therapeutic target for idiopathic pulmonary fibrosis2020

    • Author(s)
      Araki Kota、Kinoshita Rie、Tomonobu Nahoko、Gohara Yuma、Tomida Shuta、Takahashi Yuta、Senoo Satoru、Taniguchi Akihiko、Itano Junko、Yamamoto Ken-ichi、Murata Hitoshi、Suzawa Ken、Shien K、Yamamoto H、Okazaki M、Sugimoto S、Ichimura K、Nishibori M、Miyahara N、Toyooka S、Sakaguchi Masakiyo
    • Journal Title

      Journal of Molecular Medicine

      Volume: 99 Issue: 1 Pages: 131-145

    • DOI

      10.1007/s00109-020-02001-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07369, KAKENHI-PROJECT-19H03746, KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-16H06277
  • [Journal Article] Xylitol acts as an anticancer monosaccharide to induce selective cancer death via regulation of the glutathione level2020

    • Author(s)
      Tomonobu Nahoko、Komalasari Ni Luh Gede Yoni、Sumardika I Wayan、Jiang Fan、Chen Youyi、Yamamoto Ken-ichi、Kinoshita Rie、Murata Hitoshi、Inoue Yusuke、Sakaguchi Masakiyo
    • Journal Title

      Chemico-Biological Interactions

      Volume: 324 Pages: 109085-109085

    • DOI

      10.1016/j.cbi.2020.109085

    • NAID

      120006892917

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07369, KAKENHI-PROJECT-19K07474, KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-18K15320
  • [Journal Article] Analysis of a plasmid encoding botulinum neurotoxin type G gene in Clostridium argentinense2020

    • Author(s)
      Sakaguchi, Y., Uchiyama, J., Take, A., Gotoh, K., Sakaguchi, M., Suzuki, T., Yamamoto, Y., Hosomi, K., Kohda, T., Mukamoto, M., Kozaki, S., Hayashi, S., Oguma, K.
    • Journal Title

      Anaerobe

      Volume: 66 Pages: 102281-102281

    • DOI

      10.1016/j.anaerobe.2020.102281

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07560, KAKENHI-PROJECT-20K16250, KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-18K07127, KAKENHI-PROJECT-16H06277
  • [Journal Article] Neuroplastinβ-mediated upregulation of solute carrier family 22 member 18 antisense (SLC22A18AS) plays a crucial role in the epithelial-mesenchymal transition, leading to lung cancer cells' enhanced motility2020

    • Author(s)
      Bajkowska Karolina、Sumardika I. Wayan、Tomonobu Nahoko、Chen Youyi、Yamamoto Ken-ichi、Kinoshita Rie、Murata Hitoshi、Gede Yoni Komalasari Ni Luh、Jiang Fan、Yamauchi Akira、Winarsa Ruma I. Made、Kasano-Camones Carlos Ichiro、Inoue Yusuke、Sakaguchi Masakiyo
    • Journal Title

      Biochemistry and Biophysics Reports

      Volume: 22 Pages: 100768-100768

    • DOI

      10.1016/j.bbrep.2020.100768

    • NAID

      120006890008

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07369, KAKENHI-PROJECT-19K07474, KAKENHI-PROJECT-19K07676, KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-16H06277
  • [Journal Article] Convenient methodology for extraction and subsequent selective propagation of mouse melanocytes in culture from adult mouse skin tissue.2019

    • Author(s)
      Tomonobu N, Kinoshita R, Sumardika IW, Chen Y, Inoue Y, Yamauchi A, Yamamoto KI, Murata H, Sakaguchi M.
    • Journal Title

      Biochem Biophys Rep

      Volume: 9 Pages: 100619-100619

    • NAID

      120006948964

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03577
  • [Journal Article] Critical role of the MCAM-ETV4 axis triggered by extracellular S100A8/A9 in breast cancer aggressiveness.2019

    • Author(s)
      Chen Y, Sumardika IW, Tomonobu N, Kinoshita R, Inoue Y, Iioka H, Mitsui Y, Saito K, Ruma IMW, Sato H, Yamauchi A, Murata H, Yamamoto KI, Tomida S, Shien K, Yamamoto H, Soh J, Futami J, Kubo M, Putranto EW, Murakami T, Liu M, Hibino T, Nishibori M, Kondo E, Toyooka S, Sakaguchi M.
    • Journal Title

      Neoplasia.

      Volume: 21(7) Issue: 7 Pages: 627-640

    • DOI

      10.1016/j.neo.2019.04.006

    • NAID

      120006948963

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08276, KAKENHI-PROJECT-19K07369, KAKENHI-PROJECT-19K07474, KAKENHI-PROJECT-19K07676, KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-17H03590, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-18K15320
  • [Journal Article] Anti-tumor effect of neratinib against lung cancer cells harboring HER2 oncogene alterations.2019

    • Author(s)
      Ogoshi Y, Shien K, Yoshioka T, Torigoe H, Sato H, Sakaguchi M, Tomida S, Namba K, Kurihara E, Takahashi Y, Suzawa K, Yamamoto H, Soh J, Toyooka S
    • Journal Title

      Oncol Lett.

      Volume: - Pages: 2729-2736

    • DOI

      10.3892/ol.2019.9908

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-16K10681
  • [Journal Article] Melanoma cell adhesion molecule is the driving force behind the dissemination of melanoma upon S100A8/A9 binding in the original skin lesion.2019

    • Author(s)
      Chen Y, Sumardika IW, Tomonobu N, Winarsa Ruma IM, Kinoshita R, Kondo E, Inoue Y, Sato H, Yamauchi A, Murata H, Yamamoto KI, Tomida S, Shien K, Yamamoto H, Soh J, Liu M, Futami J, Sasai K, Katayama H, Kubo M, Putranto EW, Hibino T, Sun B, Nishibori M, Toyooka S, Sakaguchi M
    • Journal Title

      Cancer Lett.

      Volume: - Pages: 178-190

    • DOI

      10.1016/j.canlet.2019.03.023

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-17H03590, KAKENHI-PROJECT-19K07369, KAKENHI-PROJECT-19K07474, KAKENHI-PROJECT-19K07676, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-18K15320
  • [Journal Article] Extracellular S100A11 plays a critical role in spread of the fibroblast population in pancreatic cancers2019

    • Author(s)
      Takamatsu H, Yamamoto K, Tomonobu N, Murata H, Inoue Y, Yamauchi A, Sumardika W, Youyi C, Kinoshita R, Yamamura M, Fujiwara H, Mitsui Y, Araki K, Futami J, Saito K, Iioka H, Ruma MW, Putranto EW, Nishibori M, Kondo E, Yamamoto Y, Toyooka S, Sakaguchi M
    • Journal Title

      Oncol Res

      Volume: - Issue: 6 Pages: 713-727

    • DOI

      10.3727/096504018x15433161908259

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06889, KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-17H03590, KAKENHI-PROJECT-16K08728, KAKENHI-PROJECT-19K07369, KAKENHI-PROJECT-19K07474, KAKENHI-PROJECT-19K16714, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-18K15320
  • [Journal Article] Neuroplastin-β mediates S100A8/A9-induced lung cancer disseminative progression.2019

    • Author(s)
      Sumardika IW, Chen Y, Tomonobu N, Kinoshita R, Ruma IMW, Sato H, Kondo E, Inoue Y, Yamauchi A, Murata H, Yamamoto KI, Tomida S, Shien K, Yamamoto H, Soh J, Futami J, Putranto EW, Hibino T, Nishibori M, Toyooka S, Sakaguchi M
    • Journal Title

      Mol Carcinog.

      Volume: - Issue: 6 Pages: 980-995

    • DOI

      10.1002/mc.22987

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-19K07369, KAKENHI-PROJECT-19K07474, KAKENHI-PROJECT-17H03590, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-18K15320
  • [Journal Article] Convenient methodology for extraction and subsequent selective propagation of mouse melanocytes in culture from adult mouse skin tissue.2019

    • Author(s)
      Tomonobu N, Kinoshita R, Sumardika IW, Chen Y, Inoue Y, Yamauchi A, Yamamoto KI, Murata H, Sakaguchi M
    • Journal Title

      Biochem Biophys Rep.

      Volume: - Pages: 100619-100619

    • DOI

      10.1016/j.bbrep.2019.100619

    • NAID

      120006948964

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-19K07369, KAKENHI-PROJECT-19K07474, KAKENHI-PROJECT-19K07676, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-18K15320
  • [Journal Article] Upregulation of Mobility in Pancreatic Cancer Cells by Secreted S100A11 Through Activation of Surrounding Fibroblasts2019

    • Author(s)
      Mitsui Yosuke、Tomonobu Nahoko、Watanabe Masami、Kinoshita Rie、Sumardika I Wayan、Youyi Chen、Murata Hitoshi et al.
    • Journal Title

      Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics

      Volume: 27 Issue: 8 Pages: 945-956

    • DOI

      10.3727/096504019x15555408784978

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07369, KAKENHI-PROJECT-19K07474, KAKENHI-PROJECT-19K07676, KAKENHI-PROJECT-19K16714, KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-18K15320
  • [Journal Article] Therapeutic potential of targeting S100A11 in malignant pleural mesothelioma2018

    • Author(s)
      Sato Hiroki、Sakaguchi Masakiyo、Yamamoto Hiromasa、Tomida Shuta、Aoe Keisuke、Shien Kazuhiko、Yoshioka Takahiro、Namba Kei、Torigoe Hidejiro、Soh Junichi、Tsukuda Kazunori、Tao Hiroyuki、Okabe Kazunori、Miyoshi Shinichiro、Pass Harvey I.、Toyooka Shinichi
    • Journal Title

      Oncogenesis

      Volume: 7 Issue: 1 Pages: 11-11

    • DOI

      10.1038/s41389-017-0017-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10784, KAKENHI-PUBLICLY-16H01574, KAKENHI-PROJECT-17H03577
  • [Journal Article] Combined inhibition of MEK and PI3K pathways overcomes acquired resistance to EGFR-TKIs in non-small cell lung cancer.2018

    • Author(s)
      Sato H, Yamamoto H, Sakaguchi M, Shien K, Tomida S, Shien T, Ikeda H, Hatono M, Torigoe H, Namba K, Yoshioka T, Kurihara E, Ogoshi Y, Takahashi Y, Soh J, Toyooka S
    • Journal Title

      Cancer Sci.

      Volume: 109 Issue: 10 Pages: 3183-3196

    • DOI

      10.1111/cas.13763

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H03577
  • [Journal Article] Therapeutic strategies for afatinib-resistant lung cancer harboring HER2 alterations2018

    • Author(s)
      Torigoe Hidejiro、Shien Kazuhiko、Takeda Tatsuaki、Yoshioka Takahiro、Namba Kei、Sato Hiroki、suzawa Ken、Yamamoto Hiromasa、Soh Junichi、Sakaguchi Masakiyo、Tomida Shuta、Tsukuda Kazunori、Miyoshi Shinichiro、Toyooka Shinichi
    • Journal Title

      Cancer Sci.

      Volume: - Issue: 5 Pages: 1493-1502

    • DOI

      10.1111/cas.13571

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-17K16608
  • [Journal Article] exSSSRs (extracellular S100 soil sensor receptors)-Fc fusion proteins work as prominent decoys to S100A8/A9-induced lung tropic cancer metastasis.2018

    • Author(s)
      Kinoshita R, Sato H, Yamauchi A, Takahashi Y, Inoue Y, Sumardika IW, Chen Y, Tomonobu N, Araki K, Shien K, Tomida S, Torigoe H, Namba K, Kurihara E, Ogoshi Y, Murata H, Yamamoto KI, Futami J, Putranto EW, Ruma IMW, Yamamoto H, Soh J, Hibino T, Nishibori M, Kondo E, Toyooka S, Sakaguchi M
    • Journal Title

      Int J Cancer.

      Volume: - Issue: 12 Pages: 3138-3145

    • DOI

      10.1002/ijc.31945

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-17H03590, KAKENHI-PROJECT-16K08728, KAKENHI-PROJECT-16K19037, KAKENHI-PROJECT-19K07474, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-18K15320
  • [Journal Article] Embigin Promotes Prostate Cancer Progression by S100A4-Dependent and-Independent Mechanisms.2018

    • Author(s)
      Ruma IMW, Kinoshita R, Tomonobu N, Inoue Y, Kondo E, Yamauchi A, Sato H, Sumardika IW, Chen Y, Yamamoto KI, Murata H, Toyooka S, Nishibori M, Sakaguchi M
    • Journal Title

      Cancers (Basel)

      Volume: 10 Issue: 7 Pages: 239-239

    • DOI

      10.3390/cancers10070239

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-16K08728, KAKENHI-PROJECT-16K19037, KAKENHI-PROJECT-18K15320
  • [Journal Article] c-Jun N-terminal kinase (JNK)-mediated phosphorylation of SARM1 regulates NAD(+) cleavage activity to inhibit mitochondrial respiration.2018

    • Author(s)
      Murata H, Khine CC, Nishikawa A, Yamamoto KI, Kinoshita R, Sakaguchi M.
    • Journal Title

      J Biol Chem.

      Volume: 293 Issue: 49 Pages: 18933-18943

    • DOI

      10.1074/jbc.ra118.004578

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-16K19037, KAKENHI-PROJECT-18K15320
  • [Journal Article] Newly developed anti-S100A8/A9 monoclonal antibody efficiently prevents lung tropic cancer metastasis.2018

    • Author(s)
      Kinoshita R, Sato H, Yamauchi A, Takahashi Y, Inoue Y, Sumardika IW, Chen Y, Tomonobu N, Araki K, Shien K, Tomida S, Torigoe H, Namba K, Kurihara E, Ogoshi Y, Murata H, Yamamoto KI, Futami J, Putranto EW, Ruma IMW, Yamamoto H, Soh J, Hibino T, Nishibori M, Kondo E, Toyooka S, Sakaguchi M.
    • Journal Title

      Int J Cancer.

      Volume: 印刷中 Issue: 2 Pages: 569-575

    • DOI

      10.1002/ijc.31982

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03590, KAKENHI-PROJECT-16K08728, KAKENHI-PROJECT-16K19037, KAKENHI-PROJECT-19K07474, KAKENHI-PROJECT-19K07676, KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-18K15320
  • [Journal Article] Tumor-suppressive effect of LRIG1, a negative regulator of ErbB, in non-small cell lung cancer harboring mutant EGFR2018

    • Author(s)
      Torigoe H, Yamamoto H, Sakaguchi M, Youyi C, Numba K, Sato H, Shien K, Soh J, Suzawa K, Tomida S, Tsukuda K, Miyoshi S, Toyooka S
    • Journal Title

      Carcinogenesis

      Volume: - Issue: 5 Pages: 719-727

    • DOI

      10.1093/carcin/bgy044

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-18K08783
  • [Journal Article] Signal Diversity of Receptor for Advanced Glycation End Products2017

    • Author(s)
      Sakaguchi M, Kinoshita R, Putranto EW, Ruma IMW, Sumardika IW, Youyi C, Tomonobu N, Yamamoto KI, Murata H.
    • Journal Title

      Acta Medica Okayama

      Volume: 71 Issue: 6 Pages: 459-465

    • DOI

      10.18926/AMO/55582

    • NAID

      120006370709

    • URL

      https://ousar.lib.okayama-u.ac.jp/55582

    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K19037, KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-16K18440
  • [Journal Article] b-1,3-galactosyl-O-glycosyl-glycoprotein b-1,6-N-acetylglucosaminyltransferase 3 Increases MCAM Stability, Which Enhances S100A8/A9-Mediated Cancer Motility.2017

    • Author(s)
      Sumardika I Wayan、Youyi Chen、Kondo Eisaku、Inoue Yusuke、Ruma I Made Winarsa、Murata Hitoshi、Kinoshita Rie、Yamamoto Ken-Ichi、Tomida Shuta、Shien Kazuhiko、Satoh Hiroki、Yamauchi Akira、Futami Junichiro、Putranto Endy Widya、Hibino Toshihiko、Toyooka Shinichi、Nishibori Masahiro、Sakaguchi Masakiyo
    • Journal Title

      Oncology Reserch

      Volume: in press Issue: 3 Pages: 431-444

    • DOI

      10.3727/096504017x15031557924123

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K19037, KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-17H03590, KAKENHI-PROJECT-16K15245, KAKENHI-PROJECT-16K18440, KAKENHI-PROJECT-16K08728, KAKENHI-PROJECT-15K10201, KAKENHI-PROJECT-18K15320
  • [Journal Article] Distant Bystander Effect of REIC/DKK3 Gene Therapy Through Immune System Stimulation in Thoracic Malignancies2017

    • Author(s)
      Suzawa K, Shien K, Peng H, Sakaguchi M, Watanabe M, Hashida S, Maki Y, Yamamoto H, Tomida S, Soh J, Asano H, Tsukuda K, Nasu Y, Kumon H, Miyoshi S, Toyooka S.
    • Journal Title

      Anticancer Res

      Volume: 14 Pages: 301-307

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H03577
  • [Journal Article] Expression of tumor suppressor REIC/Dkk-3 by a newly improved adenovirus vector with insertion of an hTERT promoter at the 3’-side of the transgene.2017

    • Author(s)
      Putranto EW, Kinoshita R, Watanabe M, Sadahira T, Murata H, Yamamoto KI, Futami J, Kataoka K, Inoue Y, Ruma IM, Sumardika IW, Youyi C, Kubo M, Sakaguchi Y, Saito K, Nasu Y, Kumon H, Huh NH, and Sakaguchi M.
    • Journal Title

      Oncol. Lett.

      Volume: 14 Issue: 1 Pages: 1041-1048

    • DOI

      10.3892/ol.2017.6201

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08728, KAKENHI-PROJECT-16K08785, KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-15K01303, KAKENHI-PROJECT-16K18440
  • [Journal Article] Robust cancer-specific gene expression by a novel cassette with hTERT and CMV promoter elements.2017

    • Author(s)
      Sakaguchi M, Sadahira T, Ueki H, Kinoshita R, Murata H, Yamamoto KI, Futami J, Nasu Y, Ochiai K, Kumon H, Huh NH, Watanabe M.
    • Journal Title

      Oncology Reports

      Volume: 38 Issue: 2 Pages: 1108-1114

    • DOI

      10.3892/or.2017.5710

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K11004, KAKENHI-PROJECT-16K19037, KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-16K18440
  • [Journal Article] Periostin contributes to epidermal hyperplasia in psoriasis common to atopic dermatitis2015

    • Author(s)
      Arima K, Ohta S, Takagi A, Shiraishi H, Masuoka M, Ontsuka K, Suto H, Suzuki S, Yamamoto K-i, Ogawa M, Simmons O, Yamaguchi Y, Toda S, Aihara M, Conway SJ, Ikeda S, Izuhara K.
    • Journal Title

      Allergol. Int.

      Volume: 64 Issue: 1 Pages: 41-48

    • DOI

      10.1016/j.alit.2014.06.001

    • NAID

      130004873124

    • ISSN
      1323-8930, 1440-1592
    • URL

      https://localhost/en/publications/ebff2209-6de7-4df0-ae52-61f40a94ecbd

    • Language
      English
    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24591468, KAKENHI-PROJECT-15K09553, KAKENHI-PROJECT-15K15372, KAKENHI-PROJECT-25293224
  • [Journal Article] Periostin controls keratinocyte proliferation and differentiation by interacting with the paracrine IL-1a/IL-6 loop.2014

    • Author(s)
      Taniguchi K, Arima K, Masuoka M, Ohta S, Shiraishi H, Ontsuka K, Suzuki S, Inamitsu M, Yamamoto K-i, Simmons O, Toda S, Conway SJ, Hamasaki Y, Izuhara K.
    • Journal Title

      J Invest Dermatol

      Volume: 134 Issue: 5 Pages: 1295-1304

    • DOI

      10.1038/jid.2013.500

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24591468, KAKENHI-PROJECT-24591553, KAKENHI-PROJECT-25293224
  • [Journal Article] Periostin in Allergic Inflammation2014

    • Author(s)
      Kenji Izuhara, Kazuhiko Arima, Shoichiro Ohta, Shoichi Suzuki, Masako Inamitsu, and Ken-ichi Yamamoto
    • Journal Title

      Allergol. Int.

      Volume: 63 Issue: 2 Pages: 143-151

    • DOI

      10.2332/allergolint.13-RAI-0663

    • NAID

      130004477217

    • ISSN
      1323-8930, 1440-1592
    • URL

      https://localhost/en/publications/0be4eabd-6b04-4ac1-acf3-c7228d162284

    • Language
      English
    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24591466, KAKENHI-PROJECT-24591468, KAKENHI-PROJECT-25293224
  • [Patent] 遺伝子発現用カセット及びその産生物2018

    • Inventor(s)
      阪口政清,西堀正洋,公文裕巳,村田等,山本健一,木下理恵
    • Industrial Property Rights Holder
      阪口政清,西堀正洋,公文裕巳,村田等,山本健一,木下理恵
    • Industrial Property Rights Type
      特許
    • Filing Date
      2018
    • Overseas
    • Data Source
      KAKENHI-PROJECT-17H03577
  • [Presentation] ヒトメラノーマ細胞の増殖と血管新生における冬虫夏草の抗腫瘍作用評価2023

    • Author(s)
      長﨑直也, 堀井聡, I Wayan Sumardika, I Made Winarsa Ruma, 友信奈保子, 木下理恵, 山本健一, 村田等, 阪口政清
    • Organizer
      日本組織培養学会第95回大会
    • Data Source
      KAKENHI-PROJECT-23K27439
  • [Presentation] Novel cancer suppressing role of REIC/DKK3 protein through a downregulation of cell surface PD-L! in breast cells2023

    • Author(s)
      Y. Gohara, N. Tomonobu, R. Kinoshita, K. Yamamoto, H. Murata, M. Sakaguch
    • Organizer
      AACR2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K27439
  • [Presentation] S100A8/A9 とその新制御分子のバランスで成立するがん転移の機序解明2023

    • Author(s)
      友信奈保子, 木下理恵, 合原勇馬, Ni Luh Gede Yoni Komalasari, Fan Jiang, 村田等, 山本健一, 山内明, 近藤英作, 豊岡伸一, 西堀正洋, 阪口政清
    • Organizer
      日本組織培養学会第95回大会
    • Data Source
      KAKENHI-PROJECT-23K27439
  • [Presentation] β3 インテグリン遺伝子導入ヒト表皮角化細胞を用いた難治性潰瘍に対する新 規再生医療の開発2023

    • Author(s)
      久保美代子 、山本健一、木下理恵、米澤朋子、大橋俊孝、阪口政清
    • Organizer
      第55回日本結合組織学会学術大会
    • Data Source
      KAKENHI-PROJECT-23K27439
  • [Presentation] 糞便微生物移植治療から見出した腸内の放線菌の 生理活性評価2023

    • Author(s)
      阪口義彦, 武晃, 後藤和義, 原正也, 友信奈保子, 山本健一, 菊池雄太, 坂本光央, 加藤はる, 大宮直木, 阪口政清, 永浜政博
    • Organizer
      日本組織培養学会第95回大会
    • Data Source
      KAKENHI-PROJECT-23K27439
  • [Presentation] β3インテグリン遺伝子導入ヒト表皮角化細胞を用いた難治性潰瘍に対する新規再生医療の開発2023

    • Author(s)
      久保美代子、山本健一、木下理恵、米澤朋子、大橋俊孝、阪口政清
    • Organizer
      第55回日本結合組織学会学術大会
    • Data Source
      KAKENHI-PROJECT-20K09847
  • [Presentation] STAT1/3 シグナル経路によるNAD+代謝酵素制御を介した神経軸索変性と細胞死の抑制2023

    • Author(s)
      安井優, 村田等, 大磯和真, 越智俊樹, 友信奈保子, 山本健一, 木下理恵, 阪口政清
    • Organizer
      日本組織培養学会第95回大会
    • Data Source
      KAKENHI-PROJECT-23K27439
  • [Presentation] 正常ならびにβ3インテグリン遺伝子導入ヒト表皮角化細胞のgelatin上での細胞増殖に違いについて2023

    • Author(s)
      久保美代子、山本健一、木下理恵、阪口政清
    • Organizer
      第22回日本再生医療学会総会
    • Data Source
      KAKENHI-PROJECT-20K09847
  • [Presentation] 膵がん進展におけるS100A8/A9 の機能解析と抗体による治療への応用2023

    • Author(s)
      宮本航大, 木下理恵, 小林和子, 友信奈保子, 山本健一, 村田等, 許南浩, 豊岡伸一, 阪口政清
    • Organizer
      日本組織培養学会第95回大会
    • Data Source
      KAKENHI-PROJECT-23K27439
  • [Presentation] ヒトiPS 細胞由来神経細胞と動物モデルを用いた 軸索変性誘導分子SARM1 の阻害剤開発2023

    • Author(s)
      村田等, 安藤隆幸, 安井優, 越智俊樹, 友信奈保子, 山本健一, 木下理恵, 阪口政清
    • Organizer
      日本組織培養学会第95回大会
    • Data Source
      KAKENHI-PROJECT-23K27439
  • [Presentation] TLR4 accelerates bladder cancer progression upon interaction with S100A8/A92023

    • Author(s)
      Fan Jiang,Acosta Gonzalez Herik Rodrigo, Nahoko Tomonobu, Rie Kinoshita, Yuma Gohara, Ni Luh Gede Yoni Komalasari, Ken-ichi Yamamoto, Hitoshi Murata, Akira Yamauchi, Shinichi Toyooka, Masami Watanabe, Yasutomo Nasu, Masakiyo Sakaguchi
    • Organizer
      日本組織培養学会第95回大会
    • Data Source
      KAKENHI-PROJECT-23K27439
  • [Presentation] REIC タンパク質によるPD-L1 制御を介した抗腫瘍機序の解明2023

    • Author(s)
      合原勇馬, 友信奈保子, 木下理恵, 村田等, 山本健一, 難波正義, 許南浩, 公文裕己, 阪口政清
    • Organizer
      日本組織培養学会第95回大会
    • Data Source
      KAKENHI-PROJECT-23K27439
  • [Presentation] 亜鉛結合により活性化されるZEB1 転写因子の 乳がん進展における意義の解明2023

    • Author(s)
      山本健一, 平林大輔, 丸山顕嘉, 友信奈保子, 木下理恵, Ni Luh Gade Yoni Komalasari, 村田等, 合原勇馬, 江帆, 山内明, 栗林太, 豊岡伸一, 井上裕介, 阪口政清
    • Organizer
      日本組織培養学会第95回大会
    • Data Source
      KAKENHI-PROJECT-23K27439
  • [Presentation] β3インテグリン遺伝子導入ヒト表皮角化細胞を用いた難治性潰瘍に対する新規再生医療の開発2023

    • Author(s)
      久保美代子、山本健一、木下理恵、米澤朋子、大橋俊孝、阪口政清
    • Organizer
      第55回日本結合組織学会学術大会
    • Data Source
      KAKENHI-PROJECT-23K09079
  • [Presentation] 核内 PD-L1 は MCRIP1 を抑制することでトリプルネガティブ乳がん細胞の浸潤能を促進する2023

    • Author(s)
      合原 勇馬、友信 奈保子、木下 理恵、山本 建一、村田 等、阪口 政清
    • Organizer
      第82回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-23K27439
  • [Presentation] STAT1/3シグナル経路によるNAD+代謝酵素制御を介した軸索変性と神経細胞死の抑制2023

    • Author(s)
      村田; 等、安井 優、越智 俊樹、友信 奈保子、山本 健一、木下理恵、阪口政清
    • Organizer
      第46回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-23K27439
  • [Presentation] Lysyl oxidase-like 4 exerts an atypical role in breast cancer progression that targets the cell-surface annexin A22023

    • Author(s)
      Yoni Komalasari, Nahoko Tomonobu, Rie Kinoshita, Yuma Gohara, Kenichi Yamamoto, Hitoshi Murata, Akira Yamauchi, Futoshi Kuribayashi, Yusuke Inoue, Shinichi Toyooka , Masakiyo Sakaguchi
    • Organizer
      第82回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-23K27439
  • [Presentation] 細胞表面アネキシンA2/S100A11 結合に着目した 乳がん進行の機序解明2023

    • Author(s)
      髙橋徹多, 友信奈保子,Ni LuhGede Yoni Komalasari, 合原勇馬, 山本健一, 木下理恵, 村田等, 阪口政清
    • Organizer
      日本組織培養学会第95回大会
    • Data Source
      KAKENHI-PROJECT-23K27439
  • [Presentation] REIC/Dkk-3の受容体への結合はトリプルネガティブ乳がんのPD-L1の発現を抑制する2022

    • Author(s)
      吉澤 智香子,合原 勇馬,友信 奈保子,木下 理恵,二見 淳一郎,村田 等山本 健一,阪口 政清
    • Organizer
      第45回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-20H03516
  • [Presentation] Lysyl oxidase-like 4 is prominent in breast cancer progression through its en]ymatic activities2022

    • Author(s)
      Ni Luh Gede Yoni Komalasari, Nahoko Tomonobu, Fan Jiang, Acosta Gonzalez Herik Rodrigo, Yuma Gohara, Ken-ichi Yamamoto, Rie Kinoshita, Hitoshi Murata, Yusuke Inoue, Masakiyo Sakaguchi
    • Organizer
      日本組織培養学会第94回大会
    • Data Source
      KAKENHI-PROJECT-20H03516
  • [Presentation] HRG によるメラノーマの S100A8/A9 を介した脳指向性転移抑制効果の検討2022

    • Author(s)
      友信 奈保子、Yoni Komalasari、合原 勇馬、木下 理恵、山本 健一、山内 明、近藤 英作、豊岡 伸一、阪口 政清
    • Organizer
      第81回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-20H03516
  • [Presentation] 軸索変性誘導分子 SARM1の阻害剤開発2022

    • Author(s)
      村田 等、安藤 隆幸、大磯 和真、友信 奈保子、山本 健一、木下 理恵、阪口 政清
    • Organizer
      NEURO2022
    • Data Source
      KAKENHI-PROJECT-20H03516
  • [Presentation] REIC タンパク質による免疫チェックポイント制御機構の解明2022

    • Author(s)
      合原 勇馬、友信 奈保子、木下 理恵、山本 健一、阪口 政清
    • Organizer
      第81回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-20H03516
  • [Presentation] REIC protein suppresses tumor progression through PD-L1 regulation in cancer cells2022

    • Author(s)
      Yuma Gohara, Nahoko Tomonobu, Rie Kinoshita, Hitoshi Murata, Ken-ichi Yamamoto, Masayoshi Namba, Nam-ho Huh, Hiromi Kumon, Masakiyo Sakaguchi
    • Organizer
      日本組織培養学会第94回大会
    • Data Source
      KAKENHI-PROJECT-20H03516
  • [Presentation] S100A8/A9-NPTNb シグナルによる肺がん転移メカニズムの解析2022

    • Author(s)
      山本 健一;友信 奈保子;木下 理恵;二見 淳一郎;山内 明;豊岡 伸一;近藤 栄作;阪口 政清
    • Organizer
      第81回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-20H03516
  • [Presentation] S100A8/A9を標的とした炎症性疾患に対する治療法の開発2021

    • Author(s)
      木下 理恵 , 荒木 恒太, 佐藤 博紀 , 友信 奈保子 , 村田 等 , 山本 健一 , 許 南浩 , 豊岡 伸一 ,阪 口 政清
    • Organizer
      日本組織培養学会第93回大会
    • Data Source
      KAKENHI-PROJECT-20H03516
  • [Presentation] 培養肝細胞を用いたプラスチックラップによる細胞傷害性の解析2021

    • Author(s)
      山本 健一 , Xian Wen Tan , 有元 佐賀恵 , 押木 俊之 , 難波 正義 , 阪口 政清
    • Organizer
      日本組織培養学会第93回大会
    • Data Source
      KAKENHI-PROJECT-20H03516
  • [Presentation] キシリトールの細胞内グルタチオン調節によるがん選択的細胞死誘導機序の解明2021

    • Author(s)
      友信 奈保子,木下 理恵,山本 健一,村田 等,阪口 政清
    • Organizer
      日本組織培養学会第93回大会
    • Data Source
      KAKENHI-PROJECT-20H03516
  • [Presentation] 疾患特異的iPS細胞と動物モデルを用いたパーキンソン病における軸索変性誘導分子 SARM1のリン酸化制御解析2021

    • Author(s)
      村田 等, 越智 俊樹, 友信 奈保子, 山本 健一, 木下 理恵, 阪口 政清
    • Organizer
      日本組織培養学会第93回大会
    • Data Source
      KAKENHI-PROJECT-20H03516
  • [Presentation] 6.分泌性S100A11は膵臓癌の細胞運動性を高める腫瘍周囲の線維芽細胞を活性化する2020

    • Author(s)
      合原勇馬, 光井洋介, 友信奈保子, 木下理恵, 山本健一, 山内明, 山村真弘, 近藤英作, 豊岡伸一, 那須保友, 村田等, 阪口政清
    • Organizer
      第43回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-20H03516
  • [Presentation] 5.ロテノン誘発パーキンソニズムの病態形成におけるSARM1リン酸化制御の意義2020

    • Author(s)
      村田等, 越智俊樹, 山本健一, 木下理恵, 阪口政清
    • Organizer
      第43回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-20H03516
  • [Presentation] 膵臓がんにおける腫瘍周囲微小環境機構の解析2019

    • Author(s)
      Ken-ichi Yamamoto
    • Organizer
      先端モデル動物支援プラットフォーム 若手支援技術講習会
    • Data Source
      KAKENHI-PROJECT-19K16714
  • [Presentation] 膵がん進展に導く膵がん細胞-間質線維芽細胞クロストークを介在する分泌性S100A11ー受容体RAGE連携の役割2018

    • Author(s)
      光井 洋介、山本健一、Sumardika I Wayan、木下理恵、村田 等、二見淳一郎、高松仁、山本靖彦、西堀正洋、豊岡伸一、渡部昌実、那須保友、阪口政清
    • Organizer
      第22回日本がん免疫学会総会
    • Data Source
      KAKENHI-PROJECT-17H03577
  • [Presentation] 分泌性S100A11-受容体RAGEシグナルに着眼した膵がん間質増大のメカニズムの解明2018

    • Author(s)
      山本健一、高松仁志、光井洋介、木下理恵、村田 等、二見淳一郎、山本靖彦、西堀正洋、豊岡伸一、阪口政清
    • Organizer
      第22回日本がん免疫学会総会
    • Data Source
      KAKENHI-PROJECT-17H03577
  • [Presentation] Tumor-suppressive effect of LRIG1 in non-small cell lung cancer harboring mutant EGFR2018

    • Author(s)
      鳥越英次郎、山本寛斎、阪口政清、難波圭、佐藤博紀、枝園和彦、諏澤憲、宗淳一、冨田秀太、佃和憲、三好新一郎、豊岡伸一
    • Organizer
      第77回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17H03577
  • [Presentation] JNKによるリン酸化はSARM1のNAD分解活性を制御し、ミトコンドリア呼吸阻害を誘導する2018

    • Author(s)
      村田 等、山本健一、木下理恵、阪口政清
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-17H03577
  • [Presentation] 分泌性S100A11-受容体RAGEシグナルを介した膵臓がん周辺微小環境における間質線維芽細胞の増殖誘導の解明2018

    • Author(s)
      山本 健一、高松 仁志、友信 奈保子、光井 洋介、二見 淳一郎、木下 理恵、村田 等、阪口 政清
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-17H03577
  • [Presentation] 転移先臓器を感知する受容体2017

    • Author(s)
      阪口政清、木下 理恵、村田 等、山本 健一、日比野 利彦、許 南浩
    • Organizer
      第90回日本組織培養学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H03577
  • [Presentation] S100A8/A9を標的とした新しいがん制御法の開発2017

    • Author(s)
      木下理恵 村田等 山本健一 許南浩 日比野利彦 阪口政清
    • Organizer
      第90回日本組織培養学会
    • Data Source
      KAKENHI-PROJECT-17H03577
  • 1.  木下 理恵 (40518297)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 45 results
  • 2.  Sakaguchi Masakiyo (70379840)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 56 results
  • 3.  豊岡 伸一 (30397880)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 26 results
  • 4.  村田 等 (90579096)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 43 results
  • 5.  久保 美代子 (00098609)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 6.  近藤 英作 (30252951)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 7.  西堀 正洋 (50135943)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 8.  Izuhara Kenji (00270463)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 9.  ARIMA Kazuhiko (60336112)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 10.  SUZUKI Shoichi (40253695)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 11.  OHTA Shoichiro (20346886)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 12.  OGAWA Masahiro (90599317)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  NUNOMURA Satoshi (70424728)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  INAMITSU Masako (10711814)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 15.  NANRI Yasuhiro (00382218)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  増岡 美穂 (70588699)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  冨田 秀太 (10372111)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 11 results
  • 18.  枝園 和彦 (30708079)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 10 results
  • 19.  牧野 英一 (90314674)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  山内 明 (80372431)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 21.  友信 奈保子 (80967638)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 19 results
  • 22.  米澤 朋子 (30304299)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  大橋 俊孝 (50194262)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 24.  OKAZAKI Mikio
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 25.  SOH Junichi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 26.  SAKAGUCHI Yoshihiko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 27.  UCHIYAMA Jumpei
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 28.  SUGIMOTO Seiichiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 29.  山本 寛斉
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 30.  諏澤 憲
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 31.  村上 孝
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 32.  橘 逸勢
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 33.  松川 昭博
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 34.  白井 朋子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 35.  林 俊治
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 36.  後藤 和義
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 37.  山本 靖彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 38.  井上 裕介
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 39.  山根 正修
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 40.  坂上 倫久
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 41.  定平 卓也
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 42.  植木 英雄
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 43.  渡邉 豊彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 44.  那須 保友
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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