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Shimura Yuji  志村 勇司

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… Alternative Names

志村 勇司  シムラ ユウジ

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Researcher Number 00714685
Other IDs
Affiliation (Current) 2025: 京都府立医科大学, 医学(系)研究科(研究院), 准教授
Affiliation (based on the past Project Information) *help 2022 – 2023: 京都府立医科大学, 医学(系)研究科(研究院), 准教授
2018 – 2020: 京都府立医科大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field
Principal Investigator
Basic Section 54010:Hematology and medical oncology-related
Keywords
Principal Investigator
腫瘍免疫 / 免疫療法 / MDSC / 多発性骨髄腫 / miRNA / micro RNA / exosome / microRNA / 成熟B細胞性腫瘍 / 分子標的剤 … More / 骨髄由来免疫抑制細胞 / 免疫調節薬 / サイトカイン / 免疫調整薬 / 抗腫瘍免疫 / MIF / CCL5 / 骨髄由来抑制細胞 Less
  • Research Projects

    (2 results)
  • Research Products

    (6 results)
  • Co-Researchers

    (2 People)
  •  miRNA inhibitor cocktail for suppressing MDSC function in hematologic malignancyPrincipal Investigator

    • Principal Investigator
      志村 勇司
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Molecular mechanisms underlying the induction of myeloid-derived suppressor cells in multiple myelomaPrincipal Investigator

    • Principal Investigator
      Shimura Yuji
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      Kyoto Prefectural University of Medicine

All 2023 2022 2020 2019

All Journal Article Presentation

  • [Journal Article] Tumour‐derived exosomes promote the induction of monocytic myeloid‐derived suppressor cells from peripheral blood mononuclear cells by delivering <scp>miR</scp>‐106a‐5p and <scp>miR</scp>‐146a‐5p in multiple myeloma2023

    • Author(s)
      Mizuhara Kentaro、Shimura Yuji、Tsukamoto Taku、Kanai Akinori、Kuwahara‐Ota Saeko、Yamaguchi Junko、Muramatsu Ayako、Okamoto Haruya、Taminishi‐Katsuragawa Yoko、Kawaji‐Kanayama Yuka、Isa Reiko、Mizutani Shinsuke、Inaba Toshiya、Kuroda Junya
    • Journal Title

      British Journal of Haematology

      Volume: 203 Issue: 3 Pages: 426-438

    • DOI

      10.1111/bjh.19049

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K15330, KAKENHI-PROJECT-22K08513, KAKENHI-PROJECT-21K16246
  • [Journal Article] Lenalidomide and pomalidomide potently interfere with induction of myeloid-derived suppressor cells in multiple myeloma2020

    • Author(s)
      Kuwahara-Ota S, Shimura Y, Steinebach C, Isa R, Yamaguchi J, Nishiyama D, Fujibayashi Y, Takimoto-Shimomura T, Mizuno Y, Matsumura-Kimoto Y, Tsukamoto T, Chinen Y, Kobayashi T, Horiike S, Taniwaki M, Gutschow M, Kuroda J
    • Journal Title

      Br J Haematol

      Volume: 191 Issue: 5 Pages: 784-795

    • DOI

      10.1111/bjh.16881

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08872, KAKENHI-PROJECT-18K16125, KAKENHI-PROJECT-19K17867
  • [Presentation] miR-106a and miR-146a delivered by tumor-derived exosome promote MDSC induction in multiple myeloma2022

    • Author(s)
      水原健太郎, 志村勇司 他
    • Organizer
      日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-22K08513
  • [Presentation] Mir-106a-5p and Mir-146a-5p Delivered By Tumor-Derived Exosomes Promote the Induction of Myeloid-Derived Suppressor Cells from Normal Peripheral Blood Mononuclear Cells in Multiple Myeloma2022

    • Author(s)
      Mizuhara Kentaro, Yuji Shimura et al.
    • Organizer
      Annual meeting of American Society of Hematology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K08513
  • [Presentation] Myeloma-induced myeloid-derived suppressor cells are targeted by immunomodulatory drugs that regulate the CCL5/CCR5 axis and MIF and IRF8 expression2019

    • Author(s)
      太田沙絵子、志村勇司 他
    • Organizer
      The annual congress of EHA (European Hematology Association)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K16125
  • [Presentation] 多発性骨髄腫における骨髄由来免疫抑制細胞に対するIMiDsの抑制効果2019

    • Author(s)
      太田沙絵子、志村勇司 他
    • Organizer
      第81回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K16125
  • 1.  KURODA Junya
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 2.  水谷 信介
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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