Nagayasu Kazuki 永安一樹

Researcher Number	00717902
Other IDs
Affiliation (Current)	2025: 大阪大学, 大学院薬学研究科, 准教授
Affiliation (based on the past Project Information) *help	2024: 大阪大学, 大学院薬学研究科, 准教授 2017 – 2024: 京都大学, 薬学研究科, 助教 2016: 京都大学, 健康長寿社会の総合医療開発ユニット, 特定助教 2016: 京都大学, 大学院薬学研究科, 助教 2015: 大阪大学, 薬学研究科, 助教 2015: 大阪大学, 薬学研究科, 特任助教 2014: 大阪大学, 薬学研究科(研究院), 特任助教
Review Section/Research Field	Principal Investigator Basic Section 47040:Pharmacology-related / Pharmacology in pharmacy / Medium-sized Section 47:Pharmaceutical sciences and related fields / Basic Section 51030:Pathophysiologic neuroscience-related / Science and Engineering Except Principal Investigator Basic Section 51020:Cognitive and brain science-related / Medium-sized Section 47:Pharmaceutical sciences and related fields / Medium-sized Section 51:Brain sciences and related fields / General pharmacology / Pharmacology in pharmacy
Keywords	Principal Investigator セロトニン / 光遺伝学 / ウイルスベクター / うつ病 / 幹細胞 / 脳脊髄液 / 神経ペプチド / ストレス / ビッグデータ / 臨床情報 … More / ケミカルバイオロジー / 深層学習 / グラフ畳込みニューラルネットワーク / 薬理学 / リアルワールドデータ / TRAP / 正中縫線核 / 背側縫線核 / うつ / 抗うつ薬 / 神経細胞 / 神経幹細胞 / iPS細胞 / 精神疾患 … More Except Principal Investigator セロトニン / 背側縫線核 / サル / 光遺伝学 / 眼球運動 / 自律神経 / ストレス / 情動 / 大脳基底核 / 黒質網様体 / 拡張扁桃体 / 電子カルテ / ビッグデータ / 有害事象 / リアルワールドデータ / 認知 / 黒質網様部 / 意思決定 / 扁桃体 / 分解条床核 / 分解条症核 / 拡張偏桃体 / 光遺伝学的操作 / 扁桃体中心核 / 負の情動 / 自律神経反応 / 霊長類 / substantia nigra / basal ganglia / primate / optogenetic stimulation / amygdala / decision making / stress / serotonin / 青斑核 / 外側腕傍核 / 腕傍核 / 内受容感覚 / 結合腕傍核 / 迷走神経 / AI創薬 / ドラッグリポジショニング / 臨床予測性 / 臨床検査値 / 創薬 / 薬理学 / レセプト / 薬物依存 / 深層学習 / 臨床ビッグデータ / オントロジ / 医療情報 / 予測 / ルールマイニング / 機械学習 / 受容体親和性 / 化学構造 / 光遺伝学的 / 報酬 / 国際情報交換（アメリカ合衆国） / 幹細胞 / miRNA / 神経薬理学 / ドパミン / 精神疾患 / 強迫性障害 / うつ病 / ウイルスベクター Less

ストレス抵抗性と抗うつ薬慢性作用に共通する神経機構の解明とその創薬展開Principal Investigator
- Principal Investigator
  
  永安一樹
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Kyoto University
脳室投射セロトニン神経の共遊離ペプチド同定とうつ病のバイオマーカー確立への挑戦Principal Investigator
- Principal Investigator
  
  永安一樹
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  Osaka University
臓器感覚入力系におけるモノアミン神経細胞の情動表現解析
- Principal Investigator
  
  安田正治
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51020:Cognitive and brain science-related
- Research Institution
  Kansai Medical University
Identification of determinants of depression pathogenesis and treatmentPrincipal Investigator
- Principal Investigator
  
  Nagayasu Kazuki
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Kyoto University
低分子から中分子に至るあらゆる化学構造のヒト作用予測モデルの開発Principal Investigator
- Principal Investigator
  
  永安一樹
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Kyoto University
Drug target finding based on the analysis of real world data
- Principal Investigator
  
  Kaneko Shuji
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  Kyoto University
The neural basis of modulation in decision-making under negative emotions: Exploring the extended amygdala-basal ganglia circuit.
- Principal Investigator
  
  NAKAMURA Kae
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 51020:Cognitive and brain science-related
- Research Institution
  Kansai Medical University
Optogenetic manipulation of primate serotonin system to understand body-emotion integration
- Principal Investigator
  
  NAKAMURA Kae
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 51:Brain sciences and related fields
- Research Institution
  Kansai Medical University
The role of serotonin projection under negative emotions.
- Principal Investigator
  
  YASUDA Masaharu
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51020:Cognitive and brain science-related
- Research Institution
  Kansai Medical University
Identification of antidepressive serotonin projection as a possible target of cell transplantation therapyPrincipal Investigator
- Principal Investigator
  
  Nagayasu Kazuki
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Kyoto University
International collaboration for the study of drug action based on real-world clinical data
- Principal Investigator
  
  Kaneko Shuji
- Project Period (FY)
  2018 – 2023
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  Kyoto University
Identification and pharmacological control of serotonergic projection involved in decision making
- Principal Investigator
  
  Kaneko Shuji
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Kyoto University
Genetic tools for circuit-based drug discoveryPrincipal Investigator
- Principal Investigator
  
  Nagayasu Kazuki
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Kyoto University
Studies on mental disorder using patient-specific iPS cellsPrincipal Investigator
- Principal Investigator
  
  Nagayasu Kazuki
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Osaka University
A research on the effects of miRNAs on serotonergic neuronal functions
- Principal Investigator
  
  Hashimoto Hitoshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General pharmacology
- Research Institution
  Osaka University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 Other

All Journal Article Presentation

[Journal Article] Amelioration of obsessive-compulsive disorder by intracellular acidification of cortical neurons with a proton pump inhibitor2024
- Author(s)
  Hatakama Hikari、Asaoka Nozomi、Nagayasu Kazuki、Shirakawa Hisashi、Kaneko Shuji
- Journal Title
  
  Translational Psychiatry
  
  Volume: 14 Issue: 1 Pages: 27-27
- DOI
  10.1038/s41398-024-02731-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15291, KAKENHI-PROJECT-21K07266, KAKENHI-PROJECT-20K07064, KAKENHI-PROJECT-20H00491
[Journal Article] Wild-Type DCTN1 Suppresses the Aggregation of DCTN1 Mutants Associated with Perry Disease2024
- Author(s)
  Fukui Yuto、Shirakawa Hisashi、Kaneko Shuji、Nagayasu Kazuki
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 47 Issue: 1 Pages: 253-258
- DOI
  10.1248/bpb.b23-00828
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2024-01-24
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07266, KAKENHI-PROJECT-20K07064, KAKENHI-PROJECT-22KJ1846
[Journal Article] Inhibitors of the Mechanistic Target of Rapamycin Can Ameliorate Bortezomib-Induced Peripheral Neuropathy2023
- Author(s)
  Suzuki Mari、Zhou Zi Jian、Nagayasu Kazuki、Shirakawa Hisashi、Nakagawa Takayuki、Kaneko Shuji
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 46 Issue: 8 Pages: 1049-1056
- DOI
  10.1248/bpb.b22-00861
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2023-08-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KK0216, KAKENHI-PROJECT-19H03377
[Journal Article] Lisinopril prevents bullous pemphigoid induced by dipeptidyl peptidase 4 inhibitors via the Mas receptor pathway2023
- Author(s)
  Nozawa Keisuke、Suzuki Takahide、Kayanuma Gen、Yamamoto Hiroki、Nagayasu Kazuki、Shirakawa Hisashi、Kaneko Shuji
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 13 Pages: 1084960-1084960
- DOI
  10.3389/fimmu.2022.1084960
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07064, KAKENHI-PROJECT-18KK0216
[Journal Article] The States of Different 5-HT Receptors Located in the Dorsal Raphe Nucleus Are Crucial for Regulating the Awakening During General Anesthesia2023
- Author(s)
  Ma HaiXiang、Gu LeYuan、Wang YuLing、Xu Qing、Zhang Yuanli、Shao WeiHui、Yu Qian、Lian XiTing、Liu Lu、Gu JiaXuan、Ji Na、Liu XiaoLing、Nagayasu Kazuki、Zhang HongHai
- Journal Title
  
  Molecular Neurobiology
  
  Volume: 60 Issue: 12 Pages: 6931-6948
- DOI
  10.1007/s12035-023-03519-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07266, KAKENHI-PROJECT-20K07064
[Journal Article] Peripheral Beta-2 Adrenergic Receptors Mediate the Sympathetic Efferent Activation from Central Nervous System to Splenocytes in a Mouse Model of Fibromyalgia2023
- Author(s)
  Yamashita Shiori、Dozono Naoki、Tobori Shota、Nagayasu Kazuki、Kaneko Shuji、Shirakawa Hisashi、Ueda Hiroshi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 4 Pages: 3465-3465
- DOI
  10.3390/ijms24043465
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07064, KAKENHI-PROJECT-23K21455, KAKENHI-PROJECT-19H03377
[Journal Article] The astrocytic TRPA1 channel mediates an intrinsic protective response to vascular cognitive impairment via LIF production2023
- Author(s)
  Kakae Masashi、Nakajima Hiroki、Tobori Shota、Kawashita Ayaka、Miyanohara Jun、Morishima Misa、Nagayasu Kazuki、Nakagawa Takayuki、Shigetomi Eiji、Koizumi Schuichi、Mori Yasuo、Kaneko Shuji、Shirakawa Hisashi
- Journal Title
  
  Science Advances
  
  Volume: 9 Issue: 29 Pages: 29-29
- DOI
  10.1126/sciadv.adh0102
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07266, KAKENHI-PROJECT-20K07064, KAKENHI-PROJECT-21K19334, KAKENHI-PROJECT-19H03377, KAKENHI-PLANNED-20H05902
[Journal Article] Acetaminophen improves tardive akathisia induced by dopamine D2 receptor antagonists2023
- Author(s)
  Nagaoka Koki、Nagayasu Kazuki、Shirakawa Hisashi、Kaneko Shuji
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 151 Issue: 1 Pages: 9-16
- DOI
  10.1016/j.jphs.2022.10.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07064
[Journal Article] Increased expression of glutathione peroxidase 3 prevents tendinopathy by suppressing oxidative stress2023
- Author(s)
  Furuta Haruka、Yamada Mari、Nagashima Takuya、Matsuda Shuichi、Nagayasu Kazuki、Shirakawa Hisashi、Kaneko Shuji
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 14 Pages: 1137952-1137952
- DOI
  10.3389/fphar.2023.1137952
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07064, KAKENHI-PROJECT-18KK0216
[Journal Article] Specific Cellular Effects of Low Bortezomib Concentrations on Purified Cultures of Schwann Cells, Satellite Glial Cells, Macrophages, and Dorsal Root Ganglion Neurons2023
- Author(s)
  Zhou Zijian、Nagayasu Kazuki、Shirakawa Hisashi、Kaneko Shuji
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 46 Issue: 1 Pages: 102-110
- DOI
  10.1248/bpb.b22-00668
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2023-01-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07064, KAKENHI-PROJECT-19H03377
[Journal Article] Dorsal raphe serotonergic neurons preferentially reactivate dorsal dentate gyrus cell ensembles associated with positive experience2023
- Author(s)
  Nagai Yuma、Kisaka Yuri、Nomura Kento、Nishitani Naoya、Andoh Chihiro、Koda Masashi、Kawai Hiroyuki、Seiriki Kaoru、Nagayasu Kazuki、Kasai Atsushi、Shirakawa Hisashi、Nakazawa Takanobu、Hashimoto Hitoshi、Kaneko Shuji
- Journal Title
  
  Cell Reports
  
  Volume: 42 Issue: 3 Pages: 112149-112149
- DOI
  10.1016/j.celrep.2023.112149
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07064, KAKENHI-PROJECT-22K18655, KAKENHI-PROJECT-19H03540, KAKENHI-PROJECT-21H02628, KAKENHI-PROJECT-19K22582, KAKENHI-PUBLICLY-21H00213, KAKENHI-PROJECT-20H00492
[Journal Article] Vitamin D supplementation is effective for olanzapine-induced dyslipidemia2023
- Author(s)
  Zhou Zijian、Nagashima Takuya、Toda Chihiro、Kobayashi Mone、Suzuki Takahide、Nagayasu Kazuki、Shirakawa Hisashi、Asai Satoshi、Kaneko Shuji
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 14 Pages: 1135516-1135516
- DOI
  10.3389/fphar.2023.1135516
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07064, KAKENHI-PROJECT-20H00491
[Journal Article] Enhancement of adenosine A2A signaling improves dopamine D2 receptor antagonist-induced dyskinesia via β-arrestin signaling2023
- Author(s)
  Nagaoka Koki、Asaoka Nozomi、Nagayasu Kazuki、Shirakawa Hisashi、Kaneko Shuji
- Journal Title
  
  Frontiers in Neuroscience
  
  Volume: 16 Pages: 1082375-1082375
- DOI
  10.3389/fnins.2022.1082375
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07064, KAKENHI-PROJECT-20H00491
[Journal Article] Early Detection of Adverse Drug Reaction Signals by Association Rule Mining Using Large-Scale Administrative Claims Data2023
- Author(s)
  Hiroki Yamamoto, Gen Kayanuma, Takuya Nagashima, Chihiro Toda, Kazuki Nagayasu, Shuji Kaneko
- Journal Title
  
  Drug Safety
  
  Volume: - Issue: 4 Pages: 371-389
- DOI
  10.1007/s40264-023-01278-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0216, KAKENHI-PROJECT-21K07266, KAKENHI-PROJECT-20K07064
[Journal Article] Oxytocin ameliorates impaired social behavior in a mouse model of 3q29 deletion syndrome2022
- Author(s)
  Takemoto Tomoya、Baba Masayuki、Yokoyama Kazumasa、Kitagawa Kohei、Nagayasu Kazuki、Ago Yukio、Seiriki Kaoru、Hayata-Takano Atsuko、Kasai Atsushi、Mori Daisuke、Ozaki Norio、Takuma Kazuhiro、Hashimoto Ryota、Hashimoto Hitoshi、Nakazawa Takanobu
- Journal Title
  
  Molecular Brain
  
  Volume: 15 Issue: 1 Pages: 26-26
- DOI
  10.1186/s13041-022-00915-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21464, KAKENHI-PROJECT-20H03556, KAKENHI-PROJECT-19H05467, KAKENHI-PLANNED-18H05416, KAKENHI-PUBLICLY-20H04774, KAKENHI-PUBLICLY-21H00213, KAKENHI-PROJECT-20H03611, KAKENHI-PROJECT-21H02628, KAKENHI-PROJECT-21J15163, KAKENHI-PROJECT-21K19335, KAKENHI-PROJECT-21K06594, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-20H00492
[Journal Article] Dorsal raphe nucleus to pre-B?tzinger complex serotonergic neural circuit is involved in seizure-induced respiratory arrest2022
- Author(s)
  Ma HaiXiang、Yu Qian、Shen Yue、Lian XiTing、Gu LeYuan、Wang YuLing、Xu Qing、Lu Han、Zhao HaiTing、Zeng Chang、Nagayasu Kazuki、Zhang HongHai
- Journal Title
  
  iScience
  
  Volume: 25 Issue: 10 Pages: 105228-105228
- DOI
  10.1016/j.isci.2022.105228
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07064
[Journal Article] A selective serotonin reuptake inhibitor ameliorates obsessive compulsive disorder-like perseverative behavior by attenuating 5-HT2C receptor signaling in the orbitofrontal cortex2022
- Author(s)
  Hatakama Hikari、Asaoka Nozomi、Nagayasu Kazuki、Shirakawa Hisashi、Kaneko Shuji
- Journal Title
  
  Neuropharmacology
  
  Volume: 206 Pages: 108926-108926
- DOI
  10.1016/j.neuropharm.2021.108926
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K16009, KAKENHI-PUBLICLY-20H04774, KAKENHI-PROJECT-20K07064
[Journal Article] Claustrum mediates bidirectional and reversible control of stress-induced anxiety responses.2022
- Author(s)
  Niu M, Kasai A, Tanuma M, Seiriki K, Igarashi H, Kuwaki T, Nagayasu K, Miyaji K, Ueno H, Tanabe W, Seo K, Yokoyama R, Ohkubo J, Ago Y, Hayashida M, Inoue KI, Takada M, Yamaguchi S, Nakazawa T, Kaneko S, Okuno H, Yamanaka A, Hashimoto H.
- Journal Title
  
  Sci Adv.
  
  Volume: 8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07064
[Journal Article] Claustrum mediates bidirectional and reversible control of stress-induced anxiety responses.2022
- Author(s)
  Niu, M., Kasai, A., Tanuma, M., Seiriki, K., Igarashi, H., Kuwaki, T., Nagayasu, K., Miyaji, K., Ueno, H., Tanabe, W., Seo, K., Yokoyama, R., Ohkubo, J., Ago, Y., Hayashida, M., Inoue, K., Takada, M., Yamaguchi, S., Nakazawa, T., Kaneko, S., Okuno, H., Yamanaka, A., Hashimoto, H
- Journal Title
  
  Sci Adv.
  
  Volume: 8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-20H04774
[Journal Article] Serotonin transporter: Recent progress of in silico ligand prediction methods and structural biology towards structure-guided in silico design of therapeutic agents2022
- Author(s)
  Nagayasu Kazuki
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 148 Issue: 3 Pages: 295-299
- DOI
  10.1016/j.jphs.2022.01.004
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-20H04774, KAKENHI-PROJECT-20K07064
[Journal Article] Median raphe serotonergic neurons projecting to the interpeduncular nucleus control preference and aversion2022
- Author(s)
  Kawai Hiroyuki、Bouchekioua Youcef、Nishitani Naoya、Niitani Kazuhei、Izumi Shoma、Morishita Hinako、Andoh Chihiro、Nagai Yuma、Koda Masashi、Hagiwara Masako、Toda Koji、Shirakawa Hisashi、Nagayasu Kazuki、Ohmura Yu、Kondo Makoto、Kaneda Katsuyuki、Yoshioka Mitsuhiro、Kaneko Shuji
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 7708-7708
- DOI
  10.1038/s41467-022-35346-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07064, KAKENHI-PROJECT-21K07473, KAKENHI-PROJECT-22K11498, KAKENHI-PROJECT-22K15290, KAKENHI-PROJECT-19H03540, KAKENHI-PROJECT-19K22582, KAKENHI-PROJECT-21K18548, KAKENHI-PROJECT-23K22376
[Journal Article] Orai2 channel regulates prostaglandin E2 production in TNFα/IL1α‐stimulated astrocytes2022
- Author(s)
  Nakajima Hiroki、Fujita Sayaka、Kakae Masashi、Nagayasu Kazuki、Oh‐hora Masatsugu、Shirakawa Hisashi、Kaneko Shuji
- Journal Title
  
  Glia
  
  Volume: 70 Issue: 9 Pages: 1666-1680
- DOI
  10.1002/glia.24188
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07064, KAKENHI-PROJECT-21K19334, KAKENHI-PROJECT-23K21384
[Journal Article] Intranasal oxytocin administration ameliorates social behavioral deficits in a POGZWT/Q1038R mouse model of autism spectrum disorder2021
- Author(s)
  Kitagawa Kohei、Matsumura Kensuke、Baba Masayuki、Kondo Momoka、Takemoto Tomoya、Nagayasu Kazuki、Ago Yukio、Seiriki Kaoru、Hayata-Takano Atsuko、Kasai Atsushi、Takuma Kazuhiro、Hashimoto Ryota、Hashimoto Hitoshi、Nakazawa Takanobu
- Journal Title
  
  Molecular Brain
  
  Volume: 14 Issue: 1 Pages: 56-56
- DOI
  10.1186/s13041-021-00769-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21464, KAKENHI-PROJECT-19H05467, KAKENHI-PUBLICLY-19H04909, KAKENHI-PUBLICLY-19H05218, KAKENHI-PROJECT-18H02574, KAKENHI-PROJECT-20H03611, KAKENHI-PLANNED-18H05416, KAKENHI-PROJECT-20H00492, KAKENHI-PROJECT-20H03556, KAKENHI-PROJECT-18KT0022, KAKENHI-PROJECT-19K07121, KAKENHI-PROJECT-19H03540
[Journal Article] Pronociceptive Roles of Schwann Cell?Derived Galectin-3 in Taxane-Induced Peripheral Neuropathy2021
- Author(s)
  Koyanagi Madoka、Imai Satoshi、Matsumoto Mayuna、Iguma Yoko、Kawaguchi-Sakita Nobuko、Kotake Takeshi、Iwamitsu Yuki、Ntogwa Mpumelelo、Hiraiwa Ren、Nagayasu Kazuki、Saigo Mamiko、Ogihara Takashi、Yonezawa Atsushi、Omura Tomohiro、Nakagawa Shunsaku、Nakagawa Takayuki、Matsubara Kazuo
- Journal Title
  
  Cancer Research
  
  Volume: 81 Issue: 8 Pages: 2207-2219
- DOI
  10.1158/0008-5472.can-20-2799
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K22706, KAKENHI-PROJECT-18J21240, KAKENHI-PUBLICLY-20H04774, KAKENHI-PUBLICLY-20H05506, KAKENHI-PROJECT-20K07064, KAKENHI-PROJECT-19K22582, KAKENHI-PROJECT-19H03540, KAKENHI-PROJECT-20H03390
[Journal Article] TRPM7 is an essential regulator for volume-sensitive outwardly rectifying anion channel.2021
- Author(s)
  Numata T, Sato-Numata K, Hermosura MC, Mori Y, Okada Y
- Journal Title
  
  Commun. Biol.
  
  Volume: 4 Issue: 4 Pages: 599-599
- DOI
  10.1016/j.jphs.2021.04.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03417, KAKENHI-PUBLICLY-20H04774, KAKENHI-PUBLICLY-20H05506, KAKENHI-PROJECT-19H03377, KAKENHI-PROJECT-20K07064, KAKENHI-PROJECT-19K22582, KAKENHI-PROJECT-19H03540, KAKENHI-PROJECT-20H03390
[Journal Article] 社会的敗北ストレスによるセロトニンニューロンの変化とその役割について2021
- Author(s)
  永安一樹; 金子周司
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 39 Pages: 727-730
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22582
[Journal Article] Transient Receptor Potential Melastatin 3 Is Functionally Expressed in Oligodendrocyte Precursor Cells and Is Upregulated in Ischemic Demyelinated Lesions2021
- Author(s)
  Ohashi Kana、Shibasaki Koji、Nakazawa Hayaki、Kunimasa Ryotaro、Nagayasu Kazuki、Shirakawa Hisashi、Kaneko Shuji
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 44 Issue: 2 Pages: 181-187
- DOI
  10.1248/bpb.b20-00510
- NAID
  130007979613
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2021-02-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07064, KAKENHI-PROJECT-19K22494, KAKENHI-PUBLICLY-20H04774, KAKENHI-PROJECT-18H03124, KAKENHI-PROJECT-19H03377, KAKENHI-PROJECT-19J23074, KAKENHI-PROJECT-18K19418, KAKENHI-PROJECT-19K22582, KAKENHI-PROJECT-19H03540
[Journal Article] Prediction of pharmacological activities from chemical structures with graph convolutional neural networks2021
- Author(s)
  Sakai Miyuki、Nagayasu Kazuki、Shibui Norihiro、Andoh Chihiro、Takayama Kaito、Shirakawa Hisashi、Kaneko Shuji
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 525-525
- DOI
  10.1038/s41598-020-80113-7
- NAID
  120006951708
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07064, KAKENHI-PROJECT-18KK0216, KAKENHI-PUBLICLY-20H04774, KAKENHI-PROJECT-19H03377, KAKENHI-PROJECT-18K07356, KAKENHI-PROJECT-19K22582, KAKENHI-PUBLICLY-19H05230, KAKENHI-PROJECT-19H03540
[Journal Article] Multiple alterations in glutamatergic transmission and dopamine D2 receptor splicing in induced pluripotent stem cell-derived neurons from patients with familial schizophrenia2021
- Author(s)
  Yamamoto Kana、Kuriu Toshihiko、Takuma Kazuhiro、Ono Fumihito、Matsumoto Naomichi、Hashimoto Ryota、Hashimoto Hitoshi、Nakazawa Takanobu
- Journal Title
  
  Translational Psychiatry
  
  Volume: 11 Issue: 1 Pages: 548-548
- DOI
  10.1038/s41398-021-01676-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21464, KAKENHI-PROJECT-20H03556, KAKENHI-PROJECT-19H05467, KAKENHI-PLANNED-18H05416, KAKENHI-PUBLICLY-20H04774, KAKENHI-PUBLICLY-21H00213, KAKENHI-PROJECT-18H03944, KAKENHI-PROJECT-20H03392, KAKENHI-PROJECT-20H03611, KAKENHI-PROJECT-21H02628, KAKENHI-PROJECT-21J15163, KAKENHI-PROJECT-20K07057, KAKENHI-PROJECT-20K07064, KAKENHI-PROJECT-20K07945, KAKENHI-PROJECT-21K06594, KAKENHI-PROJECT-20K21265, KAKENHI-PROJECT-21K19335, KAKENHI-PROJECT-19H01047
[Journal Article] Striatal TRPV1 activation by acetaminophen ameliorates dopamine D2 receptor antagonists-induced orofacial dyskinesia2021
- Author(s)
  Nagaoka Koki、Nagashima Takuya、Asaoka Nozomi、Yamamoto Hiroki、Toda Chihiro、Kayanuma Gen、Siswanto Soni、Funahashi Yasuhiro、Kuroda Keisuke、Kaibuchi Kozo、Mori Yasuo、Nagayasu Kazuki、Shirakawa Hisashi、Kaneko Shuji
- Journal Title
  
  JCI Insight
  
  Volume: in press Issue: 10 Pages: 1-16
- DOI
  10.1172/jci.insight.145632
- NAID
  120007038817
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0216, KAKENHI-PROJECT-19H03417, KAKENHI-PROJECT-18K14816, KAKENHI-PUBLICLY-20H04774, KAKENHI-PROJECT-19H03377, KAKENHI-PROJECT-20K07064, KAKENHI-PROJECT-20K07965, KAKENHI-PROJECT-19K22582, KAKENHI-PROJECT-20H00491, KAKENHI-PROJECT-19H03540
[Journal Article] Drug Repurposing Prediction and Validation From Clinical Big Data for the Effective Treatment of Interstitial Lung Disease2021
- Author(s)
  Siswanto Soni、Yamamoto Hiroki、Furuta Haruka、Kobayashi Mone、Nagashima Takuya、Kayanuma Gen、Nagayasu Kazuki、Imai Yumiko、Kaneko Shuji
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 12 Pages: 635293-635293
- DOI
  10.3389/fphar.2021.635293
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-20H04774, KAKENHI-PROJECT-20K07064, KAKENHI-PROJECT-18KK0216, KAKENHI-PROJECT-17H06179, KAKENHI-PROJECT-20H00491
[Journal Article] Secreted PLA2-III is a possible therapeutic target to treat neuropathic pain2021
- Author(s)
  Tanaka Keigo、Dozono Naoki、Neyama Hiroyuki、Nagai Jun、Tsukahara Ryoko、Nagayasu Kazuki、Kaneko Shuji、Ueda Hiroshi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 568 Pages: 167-173
- DOI
  10.1016/j.bbrc.2021.06.058
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H01586, KAKENHI-PUBLICLY-20H04774, KAKENHI-PROJECT-20K07064
[Journal Article] 社会的敗北ストレスによるセロトニンニューロンの変化とその役割について2021
- Author(s)
  永安一樹, 金子周司
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 39(6) Pages: 727-730
- Data Source
  KAKENHI-PROJECT-19H03540
[Journal Article] Transient receptor potential vanilloid 4 agonist GSK1016790A improves neurological outcomes after intracerebral hemorrhage in mice2020
- Author(s)
  Asao Yasunori、Tobori Shota、Kakae Masashi、Nagayasu Kazuki、Shibasaki Koji、Shirakawa Hisashi、Kaneko Shuji
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 529 Issue: 3 Pages: 590-595
- DOI
  10.1016/j.bbrc.2020.06.103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07064, KAKENHI-PUBLICLY-20H04774, KAKENHI-PROJECT-18H03124, KAKENHI-PROJECT-19H03377, KAKENHI-PROJECT-18K19418
[Journal Article] The Role of Dorsal Raphe Serotonin Neurons in the Balance between Reward and Aversion2020
- Author(s)
  Nagai Yuma、Takayama Kaito、Nishitani Naoya、Andoh Chihiro、Koda Masashi、Shirakawa Hisashi、Nakagawa Takayuki、Nagayasu Kazuki、Yamanaka Akihiro、Kaneko Shuji
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Issue: 6 Pages: 2160-2160
- DOI
  10.3390/ijms21062160
- NAID
  120006826701
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17078, KAKENHI-PROJECT-18KK0223, KAKENHI-PROJECT-18K14919, KAKENHI-PROJECT-20K07064, KAKENHI-PUBLICLY-20H04774, KAKENHI-PROJECT-18K07356, KAKENHI-PUBLICLY-18H05124, KAKENHI-PUBLICLY-19H05016, KAKENHI-PROJECT-18H02523, KAKENHI-PROJECT-19K22582, KAKENHI-PUBLICLY-19H05230, KAKENHI-PROJECT-19H03540
[Journal Article] Acute restraint stress augments the rewarding memory of cocaine through activation of α1 adrenoceptors in the medial prefrontal cortex of mice.2020
- Author(s)
  Wada, S., Yanagida, J., Sasase, H., Zhang, T., Li, X., Kamii, H., Domoto, M., Deyama, S., Hinoi, E., Yamanaka, A., Nishitani, N., Nagayasu, K., Kaneko, S., Minami, M., Kaneda, K.
- Journal Title
  
  Neuropharmacology
  
  Volume: 166 Pages: 107968-107968
- DOI
  10.1016/j.neuropharm.2020.107968
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06520, KAKENHI-PROJECT-18KK0223, KAKENHI-PUBLICLY-19H05013, KAKENHI-PROJECT-18K14919, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19K07120, KAKENHI-PROJECT-20K07064, KAKENHI-PUBLICLY-20H04774, KAKENHI-PROJECT-18K07356, KAKENHI-PUBLICLY-18H05124, KAKENHI-PUBLICLY-19H05016, KAKENHI-PROJECT-18H02523, KAKENHI-PROJECT-19K22582, KAKENHI-PUBLICLY-19H05230, KAKENHI-PROJECT-19H03540
[Journal Article] Glutamatergic neurons in the medial prefrontal cortex mediate the formation and retrieval of cocaine-associated memories in mice2019
- Author(s)
  Zhang Tong、Yanagida Junko、Kamii Hironori、Wada Shintaro、Domoto Masaki、Sasase Hitoki、Deyama Satoshi、Takarada Takeshi、Hinoi Eiichi、Sakimura Kenji、Yamanaka Akihiro、Maejima Takashi、Mieda Michihiro、Sakurai Takeshi、Nishitani Naoya、Nagayasu Kazuki、Kaneko Shuji、Minami Masabumi、Kaneda Katsuyuki
- Journal Title
  
  Addiction Biology
  
  Volume: 印刷中 Issue: 1 Pages: 1-11
- DOI
  10.1111/adb.12723
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06520, KAKENHI-PROJECT-18K19421, KAKENHI-PROJECT-18KK0223, KAKENHI-PUBLICLY-17H05563, KAKENHI-PUBLICLY-18H04941, KAKENHI-PUBLICLY-18H04972, KAKENHI-PUBLICLY-18H05124, KAKENHI-PROJECT-16H05120, KAKENHI-PROJECT-18H02523, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-18K06519, KAKENHI-PLANNED-16H06401, KAKENHI-PUBLICLY-19H05013, KAKENHI-PROJECT-17H04399, KAKENHI-PROJECT-18H02595, KAKENHI-PROJECT-18K14919, KAKENHI-ORGANIZER-16H06400, KAKENHI-PUBLICLY-19H05016
[Journal Article] TRPM2 confers susceptibility to social stress but is essential for behavioral flexibility.2019
- Author(s)
  Andoh C, Nishitani N, Hashimoto E, Nagai Y, Takao K, Miyakawa T, Nakagawa T, Mori Y, Nagayasu K, Shirakawa H, Kaneko S.
- Journal Title
  
  Brain Res.
  
  Volume: 1704 Pages: 68-77
- DOI
  10.1016/j.brainres.2018.09.031
- NAID
  120006630995
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K14919, KAKENHI-PROJECT-18H05213, KAKENHI-PUBLICLY-17H06051, KAKENHI-PUBLICLY-18H04616, KAKENHI-PROJECT-16H05091, KAKENHI-PROJECT-16H05140, KAKENHI-PROJECT-16K01946
[Journal Article] The biological basis and application of lentiviral vector and adeno-associated viral vector in pharmacological research2019
- Author(s)
  Nagayasu Kazuki
- Journal Title
  
  Folia Pharmacologica Japonica
  
  Volume: 153 Issue: 5 Pages: 204-209
- DOI
  10.1254/fpj.153.204
- NAID
  130007649359
- ISSN
  0015-5691, 1347-8397
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K14919
[Journal Article] Pituitary adenylate cyclase-activating polypeptide modulates dendritic spine maturation and morphogenesis via microRNA-132 upregulation.2019
- Author(s)
  Hayata-Takano A, Kamo T, Kijima H, Seiriki K, Ogata K, Ago Y, Nakazawa T, Shintani Y, Higashino K, Nagayasu K, Shintani N, Kasai A, Waschek JA, Hashimoto H.
- Journal Title
  
  J Neurosci.
  
  Volume: 印刷中 Issue: 22 Pages: 4208-4220
- DOI
  10.1523/jneurosci.2468-18.2019
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19488, KAKENHI-PROJECT-16K08269, KAKENHI-PROJECT-15H04645, KAKENHI-PROJECT-17H03989, KAKENHI-PROJECT-18KT0022, KAKENHI-PUBLICLY-19H04909, KAKENHI-PUBLICLY-19H05218, KAKENHI-PROJECT-18H02574, KAKENHI-PROJECT-18K14919, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19K07121
[Journal Article] Autism-associated protein kinase D2 regulates embryonic cortical neuron development.2019
- Author(s)
  Matsumura K, Baba M, Nagayasu K, Yamamoto K, Kondo M, Kitagawa K, Takemoto T, Seiriki K, Kasai A, Ago Y, Hayata-Takano A, Shintani N, Kuriu T, Iguchi T, Sato M, Takuma K, Hashimoto R, Hashimoto H.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 519(3) Issue: 3 Pages: 626-632
- DOI
  10.1016/j.bbrc.2019.09.048
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KT0022, KAKENHI-PROJECT-19K22471, KAKENHI-PROJECT-19H05467, KAKENHI-PUBLICLY-19H04909, KAKENHI-PUBLICLY-19H05218, KAKENHI-PROJECT-17H04014, KAKENHI-PROJECT-18H02574, KAKENHI-PROJECT-17K19488, KAKENHI-PROJECT-18K14919, KAKENHI-PROJECT-16H06276, KAKENHI-PLANNED-18H05416, KAKENHI-PROJECT-19K07121
[Journal Article] Identification of neuron-type specific promoters in monkey genome and their functional validation in mice.2019
- Author(s)
  Nagai Y; Nishitani N; Yasuda M; Ueda Y; Fukui Y; Andoh C; Shirakawa H; Nakagawa T; Inoue K; Nagayasu K; Kasparov S; Nakamura K; Kaneko S
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 518 Issue: 4 Pages: 619-624
- DOI
  10.1016/j.bbrc.2019.08.101
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22470, KAKENHI-PROJECT-19K17078, KAKENHI-ORGANIZER-15H05871, KAKENHI-PUBLICLY-19H04984, KAKENHI-PROJECT-19H03335, KAKENHI-PROJECT-18K14919, KAKENHI-INTERNATIONAL-15K21731, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19K22582, KAKENHI-PUBLICLY-19H05230, KAKENHI-PROJECT-19H03540
[Journal Article] An Adenosine A2A Receptor Antagonist Improves Multiple Symptoms of Repeated Quinpirole-Induced Psychosis.2019
- Author(s)
  Asaoka N, Nishitani N, Kinoshita H, Nagai Y, Hatakama H, Nagayasu K, Shirakawa H, Nakagawa T, Kaneko S
- Journal Title
  
  eNeuro
  
  Volume: 6 Issue: 1 Pages: ENEURO.0366-18.2019
- DOI
  10.1523/eneuro.0366-18.2019
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K14919, KAKENHI-PUBLICLY-18H04616, KAKENHI-PROJECT-16H05091, KAKENHI-PROJECT-19K21244
[Journal Article] Psychiatric-disorder-related behavioral phenotypes and cortical hyperactivity in a mouse model of 3q29 deletion syndrome.2019
- Author(s)
  Baba M, Yokoyama K, Seiriki K, Naka Y, Matsumura K, Kondo M, Yamamoto K, Hayashida M, Kasai A, Ago Y, Nagayasu K, Hayata-Takano A, Takahashi A, Yamaguchi S, Mori D, Ozaki N, Yamamoto T, Takuma K, Hashimoto R, Hashimoto H, Nakazawa T.
- Journal Title
  
  Neuropsychopharmacology
  
  Volume: 44(12) Issue: 12 Pages: 2125-2135
- DOI
  10.1038/s41386-019-0441-5
- NAID
  130007811380
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KT0022, KAKENHI-PROJECT-18K19511, KAKENHI-PROJECT-19H05467, KAKENHI-PUBLICLY-19H04909, KAKENHI-PUBLICLY-19H05218, KAKENHI-PROJECT-18H04040, KAKENHI-PROJECT-17H02217, KAKENHI-PROJECT-18H02574, KAKENHI-PROJECT-17K19488, KAKENHI-PROJECT-18K14919, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-17H03989
[Journal Article] Depletion of microglia ameliorates white matter injury and cognitive impairment in a mouse chronic cerebral hypoperfusion model2019
- Author(s)
  Kakae Masashi、Tobori Shota、Morishima Misa、Nagayasu Kazuki、Shirakawa Hisashi、Kaneko Shuji
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 514 Issue: 4 Pages: 1040-1044
- DOI
  10.1016/j.bbrc.2019.05.055
- NAID
  120006636645
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03377, KAKENHI-PROJECT-18K14919
[Journal Article] Pathophysiological role of TRPM2 in age-related cognitive impairment in mice.2019
- Author(s)
  Kakae M, Miyanohara J, Morishima M, Nagayasu K, Mori Y, Shirakawa H, Kaneko S.
- Journal Title
  
  Neuroscience
  
  Volume: 408 Pages: 204-213
- DOI
  10.1016/j.neuroscience.2019.04.012
- NAID
  120006630990
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19486, KAKENHI-PROJECT-19H03377, KAKENHI-PROJECT-18K14919
[Journal Article] CRISPR/Cas9-mediated in vivo gene editing reveals that neuronal 5-HT1A receptors in the dorsal raphe nucleus contribute to body temperature regulation in mice2019
- Author(s)
  Nishitani Naoya、Ohmura Yu、Nagayasu Kazuki、Shibui Norihiro、Kaneko Shuji、Ohashi Akiko、Yoshida Takayuki、Yamanaka Akihiro、Yoshioka Mitsuhiro
- Journal Title
  
  Brain Research
  
  Volume: 1719 Pages: 243-252
- DOI
  10.1016/j.brainres.2019.06.009
- NAID
  120006885155
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07545, KAKENHI-PROJECT-19K10079, KAKENHI-PROJECT-19K17078, KAKENHI-PROJECT-18KK0223, KAKENHI-PUBLICLY-19H04976, KAKENHI-PROJECT-16K10182, KAKENHI-PROJECT-18K14919, KAKENHI-PUBLICLY-18H05124, KAKENHI-PUBLICLY-19H05016, KAKENHI-PROJECT-18H02523
[Journal Article] TRPV4 is functionally expressed in oligodendrocyte precursor cells and increases their proliferation2018
- Author(s)
  Ohashi Kana、Deyashiki Ayane、Miyake Takahito、Nagayasu Kazuki、Shibasaki Koji、Shirakawa Hisashi、Kaneko Shuji
- Journal Title
  
  Pflugers Archiv - European Journal of Physiology
  
  Volume: 470 Issue: 5 Pages: 705-716
- DOI
  10.1007/s00424-018-2130-3
- NAID
  120007006244
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19486, KAKENHI-PROJECT-15H03000, KAKENHI-PROJECT-16H05091, KAKENHI-PROJECT-18K19418, KAKENHI-PLANNED-15H05934, KAKENHI-PUBLICLY-18H04616, KAKENHI-WRAPUP-18H05199, KAKENHI-PROJECT-18H03124
[Journal Article] Manipulation of dorsal raphe serotonergic neurons modulates active coping to inescapable stress and anxiety-related behaviors in mice and rats.2018
- Author(s)
  Nishitani N, Nagayasu K, Asaoka N, Yamashiro M, Andoh C, Nagai Y, Kinoshita H, Kawai H, Shibui N, Liu B, Hewinson J, Shirakawa H, Nakagawa T, Hashimoto H, Kasparov S, Kaneko S.
- Journal Title
  
  Neuropsychopharmacology
  
  Volume: 44 Issue: 4 Pages: 721-732
- DOI
  10.1038/s41386-018-0254-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19488, KAKENHI-PROJECT-18K14919, KAKENHI-PUBLICLY-18H04616, KAKENHI-PROJECT-16H05091, KAKENHI-PROJECT-17H03989
[Journal Article] TRPM2 Exacerbates Central Nervous System Inflammation in Experimental Autoimmune Encephalomyelitis by Increasing Production of CXCL2 Chemokines.2018
- Author(s)
  Tsutsui M, Hirase R, Miyamura S, Nagayasu K, Nakagawa T, Mori Y, Shirakawa H, Kaneko S.
- Journal Title
  
  J Neurosci.
  
  Volume: 38 Issue: 39 Pages: 8484-8495
- DOI
  10.1523/jneurosci.2203-17.2018
- NAID
  120006630992
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K14919, KAKENHI-PUBLICLY-18H04616, KAKENHI-PROJECT-16H05091, KAKENHI-PROJECT-17K19486, KAKENHI-PLANNED-26111004
[Journal Article] The impact of mouse strain-specific spatial and temporal immune responses on the progression of neuropathic pain.2018
- Author(s)
  Isami K, Imai S, Sukeishi A, Nagayasu K, Shirakawa H, Nakagawa T, Kaneko S.
- Journal Title
  
  Brain Behav Immun.
  
  Volume: 74 Pages: 121-132
- DOI
  10.1016/j.bbi.2018.08.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K14919, KAKENHI-PUBLICLY-18H04616, KAKENHI-PROJECT-16H05091, KAKENHI-PROJECT-17K19722, KAKENHI-PUBLICLY-18H04696, KAKENHI-PROJECT-17H04008
[Journal Article] Neurotropin inhibits neuronal activity through potentiation of sustained Kv currents in primary cultured DRG neurons.2018
- Author(s)
  Hiroyuki Kawai, Nozomi Asaoka, Takahito Miyake, Kazuki Nagayasu, Takayuki Nakagawa, Hisashi Shirakawa, Shuji Kaneko
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: 137 Issue: 3 Pages: 313-316
- DOI
  10.1016/j.jphs.2018.05.005
- NAID
  120006630994
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-18H04616, KAKENHI-PROJECT-16H05091, KAKENHI-PROJECT-17K19722, KAKENHI-PUBLICLY-18H04696, KAKENHI-PROJECT-17H04008
[Journal Article] TRPA1 sensitization during diabetic vascular impairment contributes to cold hypersensitivity in a mouse model of painful diabetic peripheral neuropathy.2018
- Author(s)
  Haruka Hiyama, Yuichi Yano, Kanako So, Satoshi Imai, Kazuki Nagayasu, Hisashi Shirakawa, Takayuki Nakagawa, Shuji Kaneko
- Journal Title
  
  Mol Pain.
  
  Volume: 14 Pages: 1744806918789-1744806918789
- DOI
  10.1177/1744806918789812
- NAID
  120006534583
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-18H04616, KAKENHI-PROJECT-16H05091, KAKENHI-PROJECT-17K19722, KAKENHI-PUBLICLY-18H04696, KAKENHI-PROJECT-17H04008
[Journal Article] TRPM2 Channel Aggravates CNS Inflammation and Cognitive Impairment via Activation of Microglia in Chronic Cerebral Hypoperfusion2018
- Author(s)
  Miyanohara Jun、Kakae Masashi、Nagayasu Kazuki、Nakagawa Takayuki、Mori Yasuo、Arai Ken、Shirakawa Hisashi、Kaneko Shuji
- Journal Title
  
  The Journal of Neuroscience
  
  Volume: 38 Issue: 14 Pages: 3520-3533
- DOI
  10.1523/jneurosci.2451-17.2018
- NAID
  120006630983
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19486, KAKENHI-PROJECT-16H05091, KAKENHI-PROJECT-17J11466, KAKENHI-PROJECT-16K15125, KAKENHI-PUBLICLY-18H04616, KAKENHI-PLANNED-26111004
[Journal Article] Ketamine-Induced Prefrontal Serotonin Release Is Mediated by Cholinergic Neurons in the Pedunculopontine Tegmental Nucleus2018
- Author(s)
  Kinoshita Haruko、Nishitani Naoya、Nagai Yuma、Andoh Chihiro、Asaoka Nozomi、Kawai Hiroyuki、Shibui Norihiro、Nagayasu Kazuki、Shirakawa Hisashi、Nakagawa Takayuki、Kaneko Shuji
- Journal Title
  
  Int J Neuropsychopharmacol.
  
  Volume: 21 Issue: 3 Pages: 305-310
- DOI
  10.1093/ijnp/pyy007
- NAID
  120006469165
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05091, KAKENHI-PROJECT-15J05932, KAKENHI-PROJECT-16K15125
[Journal Article] Chronic antidepressant potentiates spontaneous activity of dorsal raphe serotonergic neurons by decreasing GABAB receptor-mediated inhibition of L-type calcium channels2017
- Author(s)
  Asaoka Nozomi、Nishitani Naoya、Kinoshita Haruko、Kawai Hiroyuki、Shibui Norihiro、Nagayasu Kazuki、Shirakawa Hisashi、Nakagawa Takayuki、Kaneko Shuji
- Journal Title
  
  Sci Rep
  
  Volume: 7 Issue: 1 Pages: 13609-13609
- DOI
  10.1038/s41598-017-13599-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05091, KAKENHI-PROJECT-15J05932, KAKENHI-PROJECT-16J07365, KAKENHI-PROJECT-16K15125
[Journal Article] セロトニン神経機能の光/化学遺伝学的解析の現状2017
- Author(s)
  永安　一樹
- Journal Title
  
  精神科
  
  Volume: 30 Pages: 105-110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15125
[Journal Article] High-speed and scalable whole-brain imaging in rodents and primates2017
- Author(s)
  Seiriki K, Kasai A, Hashimoto T, Schulze W, Niu M, Yamaguchi S, Nakazawa T, Inoue K, Uezono S, Takada M, Naka Y, Igarashi H, Tanuma M, Waschek JA, Ago Y, Tanaka KF, Hayata-Takano A, Nagayasu K, Shintani N, Hashimoto R, Kunii Y, Hino M, Matsumoto J, Yabe H, Nagai T, Fujita K, Matsuda T, Takuma K, Baba A, Hashimoto H
- Journal Title
  
  Neuron
  
  Volume: 94 Issue: 6 Pages: 1085-1100
- DOI
  10.1016/j.neuron.2017.05.017
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08269, KAKENHI-PROJECT-16KT0193, KAKENHI-PROJECT-17K19454, KAKENHI-PROJECT-17K19488, KAKENHI-INTERNATIONAL-15K21731, KAKENHI-PROJECT-26293020, KAKENHI-ORGANIZER-15H05871, KAKENHI-PUBLICLY-16H01611, KAKENHI-PUBLICLY-16H01621, KAKENHI-PUBLICLY-17H05565, KAKENHI-PUBLICLY-17H05567, KAKENHI-PUBLICLY-17H06030, KAKENHI-PUBLICLY-17H06062, KAKENHI-PLANNED-25117005, KAKENHI-PROJECT-16H02454, KAKENHI-PROJECT-15H03123, KAKENHI-PROJECT-16H05375, KAKENHI-PROJECT-16K15125, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-16H06297, KAKENHI-PROJECT-15H04645, KAKENHI-PROJECT-17H03989, KAKENHI-PROJECT-17H05054
[Journal Article] Elucidation of the Role of Dorsal Raphe Serotonergic Neurons in Mood Regulation Using Pharmacological and Viral Vector-based Approaches2017
- Author(s)
  Nagayasu K.
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 137 Issue: 3 Pages: 341-346
- DOI
  10.1248/yakushi.16-00240
- NAID
  130005396835
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2017-03-01
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15125
[Journal Article] Sphingosine-1-phosphate induces Ca2+ signaling and CXCL1 release via TRPC6 channel in astrocytes.2017
- Author(s)
  Shirakawa H, Katsumoto R, Iida S, Miyake T, Higuchi T, Nagashima T, Nagayasu K, Nakagawa T, Kaneko S
- Journal Title
  
  Glia
  
  Volume: 65 Issue: 6 Pages: 1005-1016
- DOI
  10.1002/glia.23141
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-16H01386, KAKENHI-PROJECT-16H05091, KAKENHI-PROJECT-26293019, KAKENHI-PROJECT-16K15125
[Journal Article] Distinct Mechanism of Cysteine Oxidation-Dependent Activation and Cold Sensitization of Human Transient Receptor Potential Ankyrin 1 Channel by High and Low Oxaliplatin2017
- Author(s)
  Miyake Takahito、Nakamura Saki、Meng Zhao、Hamano Satoshi、Inoue Keisuke、Numata Tomohiro、Takahashi Nobuaki、Nagayasu Kazuki、Shirakawa Hisashi、Mori Yasuo、Nakagawa Takayuki、Kaneko Shuji
- Journal Title
  
  Frontiers in Physiology
  
  Volume: 8 Pages: 878-878
- DOI
  10.3389/fphys.2017.00878
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19722, KAKENHI-PUBLICLY-16H01386, KAKENHI-PLANNED-26111004, KAKENHI-PROJECT-16H05091, KAKENHI-PROJECT-15K08197, KAKENHI-PROJECT-16K15125, KAKENHI-PROJECT-17H04008
[Journal Article] Colchicine alleviates acute postoperative pain but delays wound repair in mice: Roles of neutrophils and macrophages2017
- Author(s)
  Sukeishi Asami、Isami Koichi、Hiyama Haruka、Imai Satoshi、Nagayasu Kazuki、Shirakawa Hisashi、Nakagawa Takayuki、Kaneko Shuji
- Journal Title
  
  Molecular Pain
  
  Volume: 13 Pages: 1-12
- DOI
  10.1177/1744806917743680
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19722, KAKENHI-PUBLICLY-16H01386, KAKENHI-PROJECT-16H05091, KAKENHI-PROJECT-16K15125, KAKENHI-PROJECT-17H04008
[Journal Article] Pathophysiological Role of Transient Receptor Potential Ankyrin 1 in a Mouse Long-Lasting Cystitis Model Induced by an Intravesical Injection of Hydrogen Peroxide2017
- Author(s)
  Oyama Shohei、Dogishi Koji、Kodera Mizuki、Kakae Masashi、Nagayasu Kazuki、Shirakawa Hisashi、Nakagawa Takayuki、Kaneko Shuji
- Journal Title
  
  Frontiers in Physiology
  
  Volume: 8 Pages: 877-877
- DOI
  10.3389/fphys.2017.00877
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19722, KAKENHI-PUBLICLY-16H01386, KAKENHI-PROJECT-16H05091, KAKENHI-PROJECT-16K15125, KAKENHI-PROJECT-17H04008
[Journal Article] Differential gene expression profiles in neurons generated from lymphoblastoid B-cell line-derived iPS cells from monozygotic twin cases with treatment-resistant schizophrenia and discordant responses to clozapine.2017
- Author(s)
  Nakazawa T, Kikuchi M, Ishikawa M, Yamamori H, Nagayasu K, Matsumoto T, Fujimoto M, Yasuda Y, Fujiwara M, Okada S, Matsumura K, Kasai A, Hayata-Takano A, Shintani N, Numata S, Takuma K, Akamatsu W, Okano H, Nakaya A, Hashimoto H, Hashimoto R.
- Journal Title
  
  Schizophr Res.
  
  Volume: 181 Pages: 75-82
- DOI
  10.1016/j.schres.2016.10.012
- NAID
  120007037467
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01286, KAKENHI-PUBLICLY-15H01288, KAKENHI-PROJECT-15H04645, KAKENHI-PROJECT-16H05375, KAKENHI-PROJECT-15K14963, KAKENHI-PROJECT-26670122, KAKENHI-PROJECT-15K19725, KAKENHI-PROJECT-16K07222, KAKENHI-PROJECT-16K08269, KAKENHI-PROJECT-16K15125, KAKENHI-PROJECT-26293020, KAKENHI-PROJECT-15K09865
[Journal Article] Pharmacological approach for elucidating the role of dorsal raphe serotonin neurons in mood/emotion regulation2017
- Author(s)
  Nagayasu K, Kaneko S.
- Journal Title
  
  Folia Pharmacologica Japonica
  
  Volume: 149 Issue: 1 Pages: 44-47
- DOI
  10.1254/fpj.149.44
- NAID
  130005188226
- ISSN
  0015-5691, 1347-8397
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15125
[Journal Article] A new designer drug 5F-ADB activates midbrain dopaminergic neurons but not serotonergic neurons.2016
- Author(s)
  Asaoka N, Kawai H, Nishitani N, Kinoshita H, Shibui N, Nagayasu K, Shirakawa H, Kaneko S.
- Journal Title
  
  J Toxicol Sci.
  
  Volume: 41 Pages: 813-816
- NAID
  130005281915
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16H05091
[Journal Article] De novo POGZ mutations in sporadic autism disrupt the DNA-binding activity of POGZ2016
- Author(s)
  Matsumura K, Nakazawa T, Nagayasu K, Gotoda-Nishimura N, Kasai A, Hayata-Takano A, Shintani N, Yamamori H, Yasuda Y, Hashimoto R, Hashimoto H.
- Journal Title
  
  J. Mol. Psychiatry
  
  Volume: 4 Issue: 1 Pages: 1-1
- DOI
  10.1186/s40303-016-0016-x
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01288, KAKENHI-PROJECT-16H05375, KAKENHI-PROJECT-26293020, KAKENHI-PROJECT-26670122, KAKENHI-PROJECT-16K08269, KAKENHI-PROJECT-16K15125
[Journal Article] Prostaglandin D2 signaling mediated by the CRTH2 receptor is involved in MK-801-induced cognitive dysfunction.2016
- Author(s)
  Onaka Y, Shintani N, Nakazawa T, Kanoh T, Ago Y, Matsuda T, Hashimoto R, Ohi K, Hirai H, Nagata KY, Nakamura M, Kasai A, Hayata-Takano A, Nagayasu K, Takuma K, Ogawa A, Baba A, Hashimoto H.
- Journal Title
  
  Behav Brain Res.
  
  Volume: 314 Pages: 477-486
- DOI
  10.1016/j.bbr.2016.07.050
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01286, KAKENHI-PUBLICLY-15H01288, KAKENHI-PROJECT-15H04645, KAKENHI-PROJECT-16H05375, KAKENHI-PROJECT-15K14963, KAKENHI-PROJECT-26670122, KAKENHI-PROJECT-15K18874, KAKENHI-PROJECT-15K08831, KAKENHI-PROJECT-16K08269, KAKENHI-PROJECT-16K15125
[Journal Article] A new designer drug 5F-ADB activates midbrain dopaminergic neurons but not serotonergic neurons.2016
- Author(s)
  Asaoka N, Kawai H, Nishitani N, Kinoshita H, Shibui N, Nagayasu K, Shirakawa H, Kaneko S.
- Journal Title
  
  J Toxicol Sci.
  
  Volume: 41 Pages: 813-816
- NAID
  130005281915
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15125
[Journal Article] Olanzapine augments the effect of selective serotonin reuptake inhibitors by suppressing GABAergic inhibition via antagonism of 5-HT₆ receptors in the dorsal raphe nucleus.2015
- Author(s)
  Asaoka N*, Nagayasu K*, Nishitani N, Yamashiro M, Shirakawa H, Nakagawa T, Kaneko S.
- Journal Title
  
  Neuropharmacology.
  
  Volume: 95 Pages: 261-268
- DOI
  10.1016/j.neuropharm.2015.03.032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26860055, KAKENHI-PROJECT-26293019, KAKENHI-PROJECT-15J05932
[Journal Article] A mouse model of human primitive neuroectodermal tumors resulting from microenvironmentally-driven malignant transformation of orthotopically transplanted radial glial cells.2015
- Author(s)
  Malchenko S, Sredni ST, Hashimoto H, Kasai A, Nagayasu K, Xie J, Margaryan NV, Seiriki K, Lulla RR, Seftor RE, Pachman LM, Meltzer HY, Hendrix MJ, Soares MB
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 3 Pages: e0121707-e0121707
- DOI
  10.1371/journal.pone.0121707
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26670122, KAKENHI-PROJECT-26860055
[Journal Article] PACAP Enhances Axon Outgrowth in Cultured Hippocampal Neurons to a Comparable Extent as BDNF.2015
- Author(s)
  Ogata K, Shintani N, Hayata-takano A, Kamo T, Higashi S, Seiriki K, Momosaki H, Vaudy D, Vaudy H, Galas L, Kasai A, Nagayasu K, Nakazawa T, Hashimoto R, Ago Y, Matsuda T, Baba A, Hashimoto H.
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 3 Pages: e0120526-e0120526
- DOI
  10.1371/journal.pone.0120526
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-14J01466, KAKENHI-PROJECT-25460100, KAKENHI-PROJECT-25640033, KAKENHI-PROJECT-26293020, KAKENHI-PROJECT-26670122, KAKENHI-PROJECT-26860055
[Journal Article] Simultaneous neuron- and astrocyte-specific fluorescent marking.2015
- Author(s)
  Schulze W, Hayata-Takano A, Kamo T, Nakazawa T, Nagayasu K, Kasai A, Seiriki K, Shintani N, Ago Y, Farfan C, Hashimoto R, Baba A, Hashimoto H.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 459 Issue: 1 Pages: 81-86
- DOI
  10.1016/j.bbrc.2015.02.073
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-14J01466, KAKENHI-PROJECT-25293250, KAKENHI-PROJECT-25460100, KAKENHI-PROJECT-25640033, KAKENHI-PROJECT-26293020, KAKENHI-PROJECT-26670122, KAKENHI-PROJECT-26670541, KAKENHI-PROJECT-26860055
[Journal Article] p13 overexpression in pancreatic b-cells ameliorates type 2 diabetes in high-fat-fed mice2015
- Author(s)
  Higashi, S. et al.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 461 Issue: 4 Pages: 612-617
- DOI
  10.1016/j.bbrc.2015.04.074
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25670038, KAKENHI-PROJECT-26670030, KAKENHI-ORGANIZER-15H05897, KAKENHI-PROJECT-25460100, KAKENHI-PROJECT-26670541, KAKENHI-PROJECT-26860055, KAKENHI-PROJECT-25293250
[Journal Article] Identification of the role of BMP and TGF-β signaling in the trajectory of serotonergic differentiation in a rapid assay in mouse embryonic stem cells in vitro.2015
- Author(s)
  Yamasaki A, Kasai A, Toi A, Kurita M, Kimoto S, Hayata-Takano A, Nakazawa T, Nagayasu K, Shintani N, Hashimoto R, Ito A, Meltzer HY, Ago Y, Waschek JA, Onaka Y, matsuda T, Baba A, Hashimoto H.
- Journal Title
  
  Journal of Neurochemistry,
  
  Volume: 132(4) Issue: 4 Pages: 418-428
- DOI
  10.1111/jnc.12999
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25293250, KAKENHI-PROJECT-25460100, KAKENHI-PROJECT-25640033, KAKENHI-PROJECT-25670037, KAKENHI-PROJECT-26293020, KAKENHI-PROJECT-26670122, KAKENHI-PROJECT-26670541, KAKENHI-PROJECT-26860055
[Journal Article] CRTH2, a prostaglandin D2 receptor, mediates depression-related behavior in mice2015
- Author(s)
  Yusuke Onaka, Norihito Shintani, Takanobu Nakazawa, Ryota Haba, Yukio Ago, Hyper Wang, Takuya Kanoh, Atsuko Hayata-Takano, Hiroyuki Hirai, Kin-ya Nagata, Masataka Nakamura, Ryota Hashimoto, Toshio Matsuda, James A. Waschek, Atsushi Kasai, Kazuki Nagayasu, Akemichi Baba, Hitoshi Hashimoto
- Journal Title
  
  Behavioural Brain Research
  
  Volume: 284 Pages: 131-137
- DOI
  10.1016/j.bbr.2015.02.013
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-13J06144, KAKENHI-PROJECT-25293250, KAKENHI-PROJECT-25460100, KAKENHI-PROJECT-25640033, KAKENHI-PROJECT-26293020, KAKENHI-PROJECT-26670122, KAKENHI-PROJECT-26670541, KAKENHI-PROJECT-26860055, KAKENHI-PUBLICLY-15H01288, KAKENHI-PROJECT-221S0003
[Journal Article] Inhibition of histone deacetylases enhances the function of serotoninergic neurons in organotypic raphe slice cultures.2015
- Author(s)
  Asaoka N, Nagayasu K, Nishitani N, Yamashiro M, Shirakawa H, Nakagawa T, Kaneko S.
- Journal Title
  
  Neurosci Lett.
  
  Volume: 593 Pages: 72-77
- DOI
  10.1016/j.neulet.2015.03.028
- NAID
  120005657906
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26860055
[Journal Article] Whole-exome sequencing and neurite outgrowth analysis in autism spectrum disorder.2015
- Author(s)
  Hashimoto R, Nakazawa T, Tsurusaki Y, Yasuda Y, Nagayasu K, Matsumura K, Kawashima H, Yamamori H, Fujimoto M, Ohi K, Umeda-Yano S, Fukunaga M, Fujino H, Kasai A, Hayata-Takano A, Shintani N, Takeda M, Matsumoto N, Hashimoto H.
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 61 Issue: 3 Pages: 199-206
- DOI
  10.1038/jhg.2015.141
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09865, KAKENHI-PROJECT-15K14963, KAKENHI-PROJECT-26670122, KAKENHI-PROJECT-15K19660, KAKENHI-PROJECT-15K19725, KAKENHI-PUBLICLY-15H01286, KAKENHI-PUBLICLY-15H01288, KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-15H04645, KAKENHI-PROJECT-25460100, KAKENHI-PROJECT-26670541, KAKENHI-PROJECT-26860055, KAKENHI-PROJECT-25293250, KAKENHI-PROJECT-26293020, KAKENHI-PROJECT-16H05379, KAKENHI-PROJECT-16K08269
[Journal Article] Role of the 5-HT4 receptor in chronic fluoxetine treatment-induced neurogenic activity and granule cell dematuration in the dentate gyrus2015
- Author(s)
  Yuki Imoto, Toshihiko Kira, Mamiko Sukeno, Naoya Nishitani, Kazuki Nagayasu, Takayuki Nakagawa, Shuji Kaneko, Katsunori Kobayashi, Eri Segi-Nishida
- Journal Title
  
  Molecular Brain
  
  Volume: 8 Issue: 1 Pages: 29-29
- DOI
  10.1186/s13041-015-0120-3
- NAID
  120005758229
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01296, KAKENHI-PROJECT-15J05932, KAKENHI-PROJECT-25460096, KAKENHI-PROJECT-26860055
[Journal Article] Atomoxetine reverses locomotor hyperactivity, impaired novel object recognition, and prepulse inhibition impairment in mice lacking pituitary adenylate cyclase-activating polypeptide (PACAP).2015
- Author(s)
  hibasaki Y, Hayata-Takano A, Hazama K, Nakazawa T, Shintani N, Kasai A, Nagayasu K, Hashimoto R, Tanida M, Katayama T, Matsuzaki S, Yamada K, Taniike M, Onaka Y, Ago Y, Waschek JA, Köves K, Reglődi D, Tamas A, Matsuda T, Baba A, Hashimoto H.
- Journal Title
  
  Neuroscience
  
  Volume: 297 Pages: 95-104
- DOI
  10.1016/j.neuroscience.2015.03.062
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659497, KAKENHI-PROJECT-26293020, KAKENHI-PROJECT-26670122, KAKENHI-PROJECT-26860055, KAKENHI-PROJECT-15K12721, KAKENHI-PUBLICLY-15H01288, KAKENHI-PROJECT-25460100, KAKENHI-PROJECT-26670541, KAKENHI-PROJECT-26870672, KAKENHI-PROJECT-25293250
[Journal Article] Control of intermale aggression by the medial prefrontal cortex activation in the mouse2014
- Author(s)
  Takahashi A, Nagayasu K, Nishitani N, Kaneko S, Koide T
- Journal Title
  
  PLoS ONE
  
  Volume: 9(4) Issue: 4 Pages: 94657-94657
- DOI
  10.1371/journal.pone.0094657
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23650243, KAKENHI-PROJECT-23683021, KAKENHI-PUBLICLY-25116527, KAKENHI-PROJECT-26860055
[Journal Article] Raphe AMPA receptors and nicotinic acetylcholine receptors mediate ketamine-induced serotonin release in the rat prefrontal cortex.2014
- Author(s)
  Nishitani N. et al.
- Journal Title
  
  The International Journal of Neuropsychopharmacology
  
  Volume: in press Issue: 08 Pages: 1321-1326
- DOI
  10.1017/s1461145714000649
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24111527, KAKENHI-PUBLICLY-26120714, KAKENHI-PROJECT-26860055
[Journal Article] Behavioral characterization of mice overexpressing human dysbindin-12014
- Author(s)
  Shintani N, Onaka Y, Hashimoto R, Takamura H, Nagata T, Umeda-Yano S, Mouri A, Mamiya T, Haba R, Matsuzaki S, Katayama T, Yamamori H, Nakazawa T, Nagayasu K, Ago Y, Yagasaki Y, Nabeshima T, Takeda M, Hashimoto H
- Journal Title
  
  Molecular Brain
  
  Volume: 7(1) Issue: 1 Pages: 74-74
- DOI
  10.1186/s13041-014-0074-x
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-24590304, KAKENHI-PROJECT-25293250, KAKENHI-PROJECT-25461730, KAKENHI-PROJECT-25640033, KAKENHI-PROJECT-26670122, KAKENHI-PROJECT-26670541, KAKENHI-PROJECT-26860055
[Presentation] セロトニン神経による情動制御およびストレス適応とその神経機序2023
- Author(s)
  永安　一樹
- Organizer
  第64回日本神経病理学会総会学術研究会 /第66回日本神経化学会大会合同大会
- Invited
- Data Source
  KAKENHI-PROJECT-21K07266
[Presentation] 縫線核セロトニン神経による抗うつ効果・情動制御の神経機構2023
- Author(s)
  永安　一樹
- Organizer
  第53回神経精神薬理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07064
[Presentation] 光遺伝学と幹細胞技術を用いたうつ・Perry病の神経・分子機序解明2023
- Author(s)
  永安　一樹
- Organizer
  第53回神経精神薬理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-21K07266
[Presentation] セロトニン神経による情動制御およびストレス適応とその神経機序2023
- Author(s)
  永安　一樹
- Organizer
  第64回日本神経病理学会総会学術研究会 /第66回日本神経化学会大会合同大会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07064
[Presentation] 光遺伝学と幹細胞技術を用いたうつ・Perry病の神経・分子機序解明2023
- Author(s)
  永安　一樹
- Organizer
  第53回神経精神薬理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07064
[Presentation] 縫線核セロトニン神経による抗うつ効果・情動制御の神経機構2023
- Author(s)
  永安　一樹
- Organizer
  第53回神経精神薬理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-21K07266
[Presentation] The role of serotonin in emotion and decision making2019
- Author(s)
  Kazuki Nagayasu, Shuji Kaneko
- Organizer
  The 92nd Annual Meeting of the JPS
- Invited
- Data Source
  KAKENHI-PROJECT-18K14919
[Presentation] 抗うつ作用に関わる神経回路/分子機構の解析2019
- Author(s)
  永安　一樹、金子　周司
- Organizer
  生体機能と創薬シンポジウム2019
- Data Source
  KAKENHI-PROJECT-18K14919
[Presentation] Prediction of pharmacological activities from chemical structures with graph convolutional neural network2019
- Author(s)
  Miyuki Sakai, Kazuki Nagayasu, Shuji Kaneko
- Organizer
  CBI学会
- Data Source
  KAKENHI-PROJECT-18K14919
[Presentation] 情動行動におけるセロトニン神経の役割2019
- Author(s)
  永安　一樹、西谷　直也、金子　周司
- Organizer
  日本神経精神薬理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18K14919
[Presentation] Neurotropin inhibits neuronal activity through potentiation of sustained Kv currents in primary cultured DRG neurons2018
- Author(s)
  Hiroyuki Kawai, Nozomi Asaoka, Takahito Miyake, Kazuki Nagayasu, Takayuki Nakagawa, Hisashi Shirakawa, Shuji Kaneko
- Organizer
  18th World Congress of basic and clinical pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14919
[Presentation] マウス多発性硬化症モデルにおけるTRPC3/6 の役割2018
- Author(s)
  宮村咲映、永安一樹、白川久志、金子周司
- Organizer
  第68回日本薬学会近畿支部総会大会
- Data Source
  KAKENHI-PROJECT-18K14919
[Presentation] A1 型活性化アストロサイトにおけるサイトカイン産生メカニズムの解析2018
- Author(s)
  藤田沙也香、永安一樹、白川久志、金子周司
- Organizer
  第68回日本薬学会近畿支部総会大会
- Data Source
  KAKENHI-PROJECT-18K14919
[Presentation] ミクログリアにおけるTRPV4 刺激によるIL-10 産生メカニズムの解析2018
- Author(s)
  桒田沙織、富澤恵里、三宅祟仁、永安一樹、白川久志、金子周司
- Organizer
  第68回日本薬学会近畿支部総会大会
- Data Source
  KAKENHI-PROJECT-18K14919
[Presentation] セロトニン神経伝達の亢進が悲観的な意思決定に及ぼす影響2018
- Author(s)
  安藤千紘、西谷直也、澁井紀宏、永安一樹、白川久志、金子周司
- Organizer
  第68回日本薬学会近畿支部総会大会
- Data Source
  KAKENHI-PROJECT-18K14919
[Presentation] オリゴデンドロサイト前駆細胞におけるTRPV4開口は増殖を促進する2018
- Author(s)
  大橋佳奈、出屋敷綾音、三宅崇仁、永安一樹、柴崎貢志、白川久志、金子周司
- Organizer
  第133回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-18K14919
[Presentation] ゲノム編集技術を用いた脳神経核特異的セロトニン受容体欠損マウス作製の試み2017
- Author(s)
  澁井紀宏1、西谷直也1、永井佑茉1、安藤千紘1、浅岡希美1、河合洋幸1、木ノ下晴子1、白川久志1、中川貴之2、大村優3、永安一樹1、金子周司1
- Organizer
  第67回日本薬学会近畿支部総会・大会
- Data Source
  KAKENHI-PROJECT-16H05091
[Presentation] 新規強迫性障害モデル評価系の作成：妥当性評価から治療ターゲット探索まで2017
- Author(s)
  浅岡希美1、西谷直也1、永安一樹1、白川久志1、中川貴之2、金子周司1
- Organizer
  第132回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-16K15125
[Presentation] ミクログリアにおいてTRPV4の開口はLPS誘発IL10産生を促進する2017
- Author(s)
  富澤恵里、三宅崇仁、永安一樹、白川久志、金子周司
- Organizer
  第132回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-16H05091
[Presentation] Chronic antidepressant treatment increases pacemaker activity of dorsal raphe serotonergic neurons2017
- Author(s)
  Nozomi Asaoka, Naoya Nishitani, Hiroyuki Kawai, Haruko Kinoshita, Norihiro Shibui, Kazuki Nagayasu, Hisashi Shirakawa, Takayuki Nakagawa, Shuji Kaneko
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎県
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-16H05091
[Presentation] Development of the viral vector capable of optogenetic control of serotonergic neurons in rat2017
- Author(s)
  Naoya Nishitani, Nozomi Asaoka, Haruko Kinoshita, Hiroyuki Kawai, Norihiro Shibui, Kazuki Nagayasu, Hisashi Shirakawa, Takayuki Nakagawa, Shuji Kaneko
- Organizer
  第９０回薬理学会年会
- Place of Presentation
  長崎県
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PROJECT-16K15125
[Presentation] TRPM2を介したケモカインCXCL2産生が多発性硬化症の増悪に関与する2017
- Author(s)
  平瀬僚、筒井真人、永安一樹、白川久志、金子周司
- Organizer
  第131回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-16K15125
[Presentation] Pathophysiological role of TRPM2 in a mouse model of vascular dementia2017
- Author(s)
  Jun Miyanohara, Masashi Kakae, Kazuki Nagayasu, Hisashi Shirakawa, Shuji Kaneko
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎県
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-16H05091
[Presentation] Chronic treatment with a selective serotonin reuptake inhibitor increases spontaneous activity of dorsal raphe nucleus serotonergic neurons through activating L-type voltage dependent Ca2+ channels2017
- Author(s)
  Nozomi Asaoka1, Naoya Nishitani1, Haruko Kinoshita1, Hiroyuki Kawai1, Norihiro Shibui1, Kazuki Nagayasu1, Hisashi Shirakawa1, Takayuki Nakagawa2, Shuji Kaneko1
- Organizer
  Neuroscience2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15125
[Presentation] Development of the viral vector capable of optogenetic control of serotonergic neurons in rat2017
- Author(s)
  Naoya Nishitani, Nozomi Asaoka, Haruko Kinoshita, Hiroyuki Kawai, Norihiro Shibui, Kazuki Nagayasu, Hisashi Shirakawa, Takayuki Nakagawa, Shuji Kaneko
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎県
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PROJECT-16H05091
[Presentation] ゲノム編集技術を用いた脳神経核特異的セロトニン受容体欠損マウス作製の試み2017
- Author(s)
  澁井紀宏1、西谷直也1、永井佑茉1、安藤千紘1、浅岡希美1、河合洋幸1、木ノ下晴子1、白川久志1、中川貴之2、大村優3、永安一樹1、金子周司1
- Organizer
  第67回日本薬学会近畿支部総会・大会
- Data Source
  KAKENHI-PROJECT-16K15125
[Presentation] ケタミンの前頭前野セロトニン遊離作用におけるアセチルコリン神経核の関与2017
- Author(s)
  木ノ下晴子1、西谷直也1、浅岡希美1、河合洋幸1、澁井紀宏1、永井佑茉1、安藤千紘1、永安一樹1、白川久志1、中川貴之2、金子周司1
- Organizer
  第132回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-16H05091
[Presentation] 新規強迫性障害モデル評価系の作成：妥当性評価から治療ターゲット探索まで2017
- Author(s)
  浅岡希美1、西谷直也1、永安一樹1、白川久志1、中川貴之2、金子周司1
- Organizer
  第132回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-16H05091
[Presentation] ミクログリアにおいてTRPV4の開口はLPS誘発IL10産生を促進する2017
- Author(s)
  富澤恵里、三宅崇仁、永安一樹、白川久志、金子周司
- Organizer
  第132回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-16K15125
[Presentation] TRPM2を介したケモカインCXCL2産生が多発性硬化症の増悪に関与する2017
- Author(s)
  平瀬僚、筒井真人、永安一樹、白川久志、金子周司
- Organizer
  第131回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-16H05091
[Presentation] Chronic treatment with a selective serotonin reuptake inhibitor increases spontaneous activity of dorsal raphe nucleus serotonergic neurons through activating L-type voltage dependent Ca2+ channels2017
- Author(s)
  Nozomi Asaoka1, Naoya Nishitani1, Haruko Kinoshita1, Hiroyuki Kawai1, Norihiro Shibui1, Kazuki Nagayasu1, Hisashi Shirakawa1, Takayuki Nakagawa2, Shuji Kaneko1
- Organizer
  Neuroscience2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05091
[Presentation] ケタミンの前頭前野セロトニン遊離作用におけるアセチルコリン神経核の関与2017
- Author(s)
  木ノ下晴子1、西谷直也1、浅岡希美1、河合洋幸1、澁井紀宏1、永井佑茉1、安藤千紘1、永安一樹1、白川久志1、中川貴之2、金子周司1
- Organizer
  第132回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-16K15125
[Presentation] Chronic antidepressant treatment increases pacemaker activity of dorsal raphe serotonergic neurons2017
- Author(s)
  Nozomi Asaoka, Naoya Nishitani, Hiroyuki Kawai, Haruko Kinoshita, Norihiro Shibui, Kazuki Nagayasu, Hisashi Shirakawa, Takayuki Nakagawa, Shuji Kaneko
- Organizer
  第９０回薬理学会年会
- Place of Presentation
  長崎県
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-16K15125
[Presentation] マウス慢性脳低灌流モデルにおけるTRPA1欠損の影響2017
- Author(s)
  抱将史、宮之原遵、永安一樹、白川久志、金子周司
- Organizer
  第67回日本薬学会近畿支部総会・大会
- Data Source
  KAKENHI-PROJECT-16H05091
[Presentation] 神経障害性疼痛および術後痛の病態形成に好中球の早期浸潤が与える影響2016
- Author(s)
  助石有沙美, 勇昂一, 今井哲司, 永安一樹, 白川久志, 中川貴之, 金子周司
- Organizer
  第129回日本薬理学会近畿部会
- Place of Presentation
  広島県
- Year and Date
  2016-06-24
- Data Source
  KAKENHI-PROJECT-16H05091
[Presentation] ケタミンの前頭前野セロトニン遊離作用におけるコリン作動性神経の関与2016
- Author(s)
  ○木ノ下晴子、西谷直也、永安一樹、浅岡希美、河合洋幸、澁井紀宏、白川久志、中川貴之、金子周司
- Organizer
  第66回日本薬学会近畿支部総会・大会
- Place of Presentation
  大阪府
- Year and Date
  2016-10-15
- Data Source
  KAKENHI-PROJECT-16K15125
[Presentation] 背側縫線核セロトニン神経による情動調節機構―ウイルスベクターを用いて―2016
- Author(s)
  永安　一樹、金子　周司
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  神奈川県
- Year and Date
  2016-03-11
- Data Source
  KAKENHI-PROJECT-26860055
[Presentation] Studies on the molecular mechanism of clozapine action with iPSC technology2016
- Author(s)
  M. Fujiwara, M. Kikuchi, K. Nagayasu, T. nakazawa, H. Yamamori, A. Kasai, A. Hayata-Takano, N. Shintani, M. Fujimoto, Y. Yasuda, M. Ishikawa, W. Akamatsu, H. Okano, A. Nakaya, H. Hashimoto, R. Hashimoto
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  神奈川県
- Year and Date
  2016-03-11
- Data Source
  KAKENHI-PROJECT-26860055
[Presentation] マウス多発性硬化症モデルにおけるTRPM2 の病態生理学的役割2016
- Author(s)
  平瀬僚、筒井真人、永安一樹、白川久志、中川貴之、金子周司
- Organizer
  第66回日本薬学会近畿支部総会・大会
- Place of Presentation
  大阪府
- Year and Date
  2016-10-15
- Data Source
  KAKENHI-PROJECT-16K15125
[Presentation] 危険ドラッグ5F-ADB のドパミン・セロトニン神経活動に対する作用2016
- Author(s)
  浅岡希美, 河合洋幸, 西谷直也, 木ノ下晴子, 澁井紀宏, 永安一樹, 白川久志, 金子周司
- Organizer
  第130回日本薬理学会近畿部会
- Place of Presentation
  京都府
- Year and Date
  2016-11-19
- Data Source
  KAKENHI-PROJECT-16K15125
[Presentation] マウスミクログリアの貪食におけるTRPV チャネルの機能解析2016
- Author(s)
  富澤恵里、三宅崇仁、永安一樹、白川久志、中川貴之、金子周司
- Organizer
  第66回日本薬学会近畿支部総会・大会
- Place of Presentation
  大阪府
- Year and Date
  2016-10-15
- Data Source
  KAKENHI-PROJECT-16K15125
[Presentation] オリゴデンドロサイト前駆細胞の増殖および分化におけるTRPV4 の生理的役割2016
- Author(s)
  出屋敷綾音, 三宅崇仁, 永安一樹, 白川久志, 中川貴之, 金子周司
- Organizer
  第130回日本薬理学会近畿部会
- Place of Presentation
  京都府
- Year and Date
  2016-11-19
- Data Source
  KAKENHI-PROJECT-16K15125
[Presentation] アデノ・アデノ随伴・レンチウイルスベクターの作製と応用2016
- Author(s)
  永安　一樹
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  神奈川県
- Year and Date
  2016-03-10
- Data Source
  KAKENHI-PROJECT-26860055
[Presentation] 神経細胞の成熟におけるPACAPとBDNFの役割2016
- Author(s)
  早田敦子、加茂俊彦、勢力薫、尾形勝弥、中澤敬信、吾郷由希夫、永安一樹、笠井淳司、新谷紀人、橋本均
- Organizer
  第38回日本生物学的精神医学会・第59回日本神経化学会大会合同年会
- Place of Presentation
  福岡
- Year and Date
  2016-09-08
- Data Source
  KAKENHI-PROJECT-26670122
[Presentation] 危険ドラッグ5F-ADB のドパミン・セロトニン神経活動に対する作用2016
- Author(s)
  浅岡希美, 河合洋幸, 西谷直也, 木ノ下晴子, 澁井紀宏, 永安一樹, 白川久志, 金子周司
- Organizer
  第130回日本薬理学会近畿部会
- Place of Presentation
  京都府
- Year and Date
  2016-11-19
- Data Source
  KAKENHI-PROJECT-16H05091
[Presentation] 過酸化水素誘発膀胱炎モデルにおけるTRPA1の病態生理学的役割2016
- Author(s)
  尾山翔平, 土岸広治, 小寺みずき, 永安一樹, 白川久志, 中川貴之, 金子周司
- Organizer
  第130回日本薬理学会近畿部会
- Place of Presentation
  京都府
- Year and Date
  2016-11-19
- Data Source
  KAKENHI-PROJECT-16K15125
[Presentation] 細胞種特異的レンチウイルスベクターを用いたセロトニン神経機能の光遺伝学的解析2016
- Author(s)
  永安一樹
- Organizer
  第66回日本薬学会近畿支部総会・大会
- Place of Presentation
  大阪府
- Year and Date
  2016-10-15
- Invited
- Data Source
  KAKENHI-PROJECT-16K15125
[Presentation] 培養後根神経節ニューロンにおけるノイロトロピンの作用解析2016
- Author(s)
  河合洋幸、浅岡希美、三宅崇仁、永安一樹、白川久志、今井哲司、中川貴之、金子周司
- Organizer
  第66回日本薬学会近畿支部総会・大会
- Place of Presentation
  大阪府
- Year and Date
  2016-10-15
- Data Source
  KAKENHI-PROJECT-16K15125
[Presentation] 神経障害性疼痛および術後痛の病態形成に好中球の早期浸潤が与える影響2016
- Author(s)
  助石有沙美, 勇昂一, 今井哲司, 永安一樹, 白川久志, 中川貴之, 金子周司
- Organizer
  第129回日本薬理学会近畿部会
- Place of Presentation
  広島県
- Year and Date
  2016-06-24
- Data Source
  KAKENHI-PROJECT-16K15125
[Presentation] 過酸化水素誘発膀胱炎モデルにおけるTRPA1の病態生理学的役割2016
- Author(s)
  尾山翔平, 土岸広治, 小寺みずき, 永安一樹, 白川久志, 中川貴之, 金子周司
- Organizer
  第130回日本薬理学会近畿部会
- Place of Presentation
  京都府
- Year and Date
  2016-11-19
- Data Source
  KAKENHI-PROJECT-16H05091
[Presentation] 糖尿病性神経障害モデルにおける感覚異常の病態解析とTRPA1の関与2016
- Author(s)
  緋山遥、宗可奈子、矢野佑一、永安一樹、白川久志、中川貴之、金子周司
- Organizer
  第66回日本薬学会近畿支部総会・大会
- Place of Presentation
  大阪府
- Year and Date
  2016-10-15
- Data Source
  KAKENHI-PROJECT-16K15125
[Presentation] オリゴデンドロサイト前駆細胞の増殖および分化におけるTRPV4 の生理的役割2016
- Author(s)
  出屋敷綾音, 三宅崇仁, 永安一樹, 白川久志, 中川貴之, 金子周司
- Organizer
  第130回日本薬理学会近畿部会
- Place of Presentation
  京都府
- Year and Date
  2016-11-19
- Data Source
  KAKENHI-PROJECT-16H05091
[Presentation] 自閉症の疾患特異的候補遺伝子の機能的スクリーニング2015
- Author(s)
  松村憲佑, 橋本亮太, 中澤敬信, 鶴崎美徳, 安田由華, 永安一樹, 川島和, 山森英長, 藤本美智子, 大井一高, 梅田知美, 福永雅喜, 藤野陽生, 笠井淳司, 早田敦子, 新谷紀人, 武田雅俊, 松本直通, 橋本均
- Organizer
  第38回日本神経科学会大会
- Place of Presentation
  神戸国際会議場（兵庫・神戸市）
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-26670122
[Presentation] がん治療後の脳機能障害の解明に有用な動物モデルの作製2015
- Author(s)
  尾中勇祐, 木野村元彦, 新谷紀人, 平井博之, 永田欽也, 中村正孝, 長谷部茂, 永安一樹, 吾郷由希夫, 笠井淳司, 早田敦子, 中澤敬信, 田熊一敞, 松田敏夫, 馬場明道, 橋本均
- Organizer
  第127回日本薬理学会近畿部会
- Place of Presentation
  長良川国際会議場（岐阜・岐阜市）
- Year and Date
  2015-06-26
- Data Source
  KAKENHI-PROJECT-26670122
[Presentation] セロトニン神経機能に関わる遺伝子発現に対するmiRNAの作用2015
- Author(s)
  大住康晃, 永安一樹, 笠井淳司, 木本早紀, 尾中勇祐, 早田敦子, 中澤敬信, 新谷紀人, 橋本　均
- Organizer
  第128回日本薬理学会近畿部会
- Place of Presentation
  大阪府
- Year and Date
  2015-11-20
- Data Source
  KAKENHI-PROJECT-26860055
[Presentation] Practical optimization of in situ hybridization procedure for the detection of microRNAs and mRNA expression in brain tissues2015
- Author(s)
  Kasai A, Kakihara S, Okada R, Hazama K, Nakazawa T, Nagayasu K, Hayata-Takano A, Shintani N, Hashimoto H.
- Organizer
  45th Society for Neuroscience Annual meeting (Neuroscience2015)
- Place of Presentation
  シカゴ（アメリカ）
- Year and Date
  2015-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670122
[Presentation] がん治療後の脳機能障害の解明に有用な動物モデルの作製2015
- Author(s)
  尾中勇祐、木野村元彦、新谷紀人、平井博之、永田欽也、中村正孝、長谷部茂、永安一樹、吾郷由希夫、笠井淳司、早田敦子、中澤敬信、田熊一敞、松田敏夫、馬場明道、橋本均
- Organizer
  第127回日本薬理学会近畿部会
- Place of Presentation
  岐阜県
- Year and Date
  2015-06-26
- Data Source
  KAKENHI-PROJECT-26860055
[Presentation] miRNAを介したPACAPによる樹状突起スパイン形成機構2015
- Author(s)
  加茂俊彦、早田敦子、勢力薫、尾形勝弥、中澤敬信, 永安一樹, 笠井淳司, 新谷紀人, 橋本均
- Organizer
  第45回日本神経精神薬理学会・第37回日本生物学的精神医学会合同年会
- Place of Presentation
  東京都
- Year and Date
  2015-09-24
- Data Source
  KAKENHI-PROJECT-26860055
[Presentation] Practical optimization of.in situ hybridization procedure for the detection of microRNAs and mRNA expression in brain tissues2015
- Author(s)
  Kasai A, Kakihara S, Okada R, Hazama K, Nakazawa T, Nagayasu K, Hayata-Takano A, Shintani N, Hashimoto H
- Organizer
  Neuroscience 2015
- Place of Presentation
  シカゴ
- Year and Date
  2015-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860055
[Presentation] A screening method for functional analysis of autism-associated genes2015
- Author(s)
  Matsumura K., Hashimoto R., Nakazawa T., Tsurusaki Y., Yasuda Y., Nagayasu K., Kawashima H., Yamamori H., Fujimoto M, Ohi K., Satomi U., Fukunaga M., Fujino H., Kasai A., Hayata A., Shintani N., Takeda M., Matsumoto N., Hashimoto H.
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  兵庫県
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-26860055
[Presentation] LPS誘発炎症モデルにおいて発現変化する脳内miRNAの同定2014
- Author(s)
  柿原　素楽、笠井　淳司、岡田　遼、尾中　勇祐、中澤　敬信、永安　一樹、早田　敦子、新谷　紀人、橋本　均
- Organizer
  第126回　日本薬理学会　近畿部会
- Place of Presentation
  和歌山
- Year and Date
  2014-10-24
- Data Source
  KAKENHI-PROJECT-26670122
[Presentation] オランザピンの縫線核セロトニン神経に対する作用とSSRI作用増強機構2014
- Author(s)
  浅岡希美、永安一樹、西谷直也、山城茉弓、白川久志、中川貴之、金子周司
- Organizer
  第125回日本薬理学会近畿部会
- Place of Presentation
  岡山
- Year and Date
  2014-06-20
- Data Source
  KAKENHI-PROJECT-26860055
[Presentation] Lentiviral vector system for potent gene expression in serotonergic neurons of rats and mice
- Author(s)
  K. NAGAYASU, N. NISHITANI, N. ASAOKA, M. YAMASHIRO, H. SHIRAKAWA, T. NAKAGAWA, S. KASPAROV, S. KANEKO
- Organizer
  Neuroscience 2014
- Place of Presentation
  Washington, DC, USA
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-26860055
[Presentation] コルチコステロン誘発性うつ病モデルを用いたプロスタノイド受容体DP2を介する情動制御機構の解析
- Author(s)
  尾中　勇祐、新谷　紀人、木野村　元彦、平井　博之、長田　欽也、中村　正孝、早田　敦子、笠井　淳司、永安　一樹、中澤　敬信、馬場　明道、橋本　均
- Organizer
  生体機能と創薬シンポジウム2014
- Place of Presentation
  大阪
- Year and Date
  2014-08-28 – 2014-08-29
- Data Source
  KAKENHI-PROJECT-26670122
[Presentation] 精神・神経疾患モデル動物の病態解析のための三次元全脳形態計測法の構築
- Author(s)
  勢力薫、笠井淳司、丹生光咲、早田敦子、永安一樹、中澤敬信、新谷紀人、橋本岳、橋本均
- Organizer
  第36回日本生物学的精神医学会第57回日本神経化学会大会合同年会
- Place of Presentation
  奈良
- Year and Date
  2014-09-29 – 2014-10-01
- Data Source
  KAKENHI-PROJECT-26860055
[Presentation] 光遺伝学的手法を用いた背側縫線核セロトニン神経特異的制御による行動学的変化
- Author(s)
  西谷直也、永安一樹、浅岡希美、山城茉弓、白川久志、中川貴之、金子周司
- Organizer
  2014年度包括脳ネットワーク冬のシンポジウム
- Place of Presentation
  東京
- Year and Date
  2014-12-12 – 2014-12-13
- Data Source
  KAKENHI-PROJECT-26860055
[Presentation] 自閉症の疾患特異的候補遺伝子の機能的スクリーニング系の確立
- Author(s)
  松村憲佑、永安一樹、中澤敬信、安田由華、山森英長、梅田知美、大井一高、橋本亮太、武田雅俊、橋本均
- Organizer
  第24回日本臨床精神神経薬理学会第44回日本神経精神薬理学会合同年会
- Place of Presentation
  名古屋
- Year and Date
  2014-11-20 – 2014-11-22
- Data Source
  KAKENHI-PROJECT-26860055
[Presentation] 自閉症の疾患特異的候補遺伝子の機能的スクリーニング系の確立
- Author(s)
  松村　憲佑、永安　一樹、中澤　敬信、安田　由華、山森　英長、梅田　知美、大井　一高、橋本　亮太、武田　雅俊、橋本　均
- Organizer
  第24回日本臨床精神神経薬理学会第44回日本神経精神薬理学会合同年会
- Place of Presentation
  名古屋
- Year and Date
  2014-11-20 – 2014-11-22
- Data Source
  KAKENHI-PROJECT-26670122
[Presentation] 精神・神経疾患モデル動物の病態解析のための三次元全脳形態計測法の構築
- Author(s)
  勢力　薫、笠井　淳司、丹生　光咲、早田　敦子、永安　一樹、中澤　敬信、新谷　紀人、橋本　岳、橋本　均
- Organizer
  第36回日本生物学的精神医学会第57回日本神経化学会大会合同年会
- Place of Presentation
  奈良
- Year and Date
  2014-09-29 – 2014-10-01
- Data Source
  KAKENHI-PROJECT-26670122
[Presentation] 神経ペプチドPACAPによる精神機能調節：創薬への展望
- Author(s)
  橋本　均、新谷　紀人、早田　敦子、笠井　淳司、永安　一樹、中澤　敬信
- Organizer
  第36回日本生物学的精神医学会第57回日本神経化学会大会合同年会
- Place of Presentation
  奈良
- Year and Date
  2014-09-29 – 2014-10-01
- Data Source
  KAKENHI-PROJECT-26670122
[Presentation] 自閉スペクトラム症関連候補遺伝子のハイスループット機能評価系による解析
- Author(s)
  永安一樹、松村憲佑、中澤敬信、安田由華、山森英長、梅田知美、大井一高、橋本亮太、武田雅俊、橋本均
- Organizer
  2014年度包括脳ネットワーク冬のシンポジウム
- Place of Presentation
  東京
- Year and Date
  2014-12-12 – 2014-12-13
- Data Source
  KAKENHI-PROJECT-26860055
[Presentation] iPS細胞関連技術を用いた統合失調症研究
- Author(s)
  中澤敬信、橋本亮太、永安一樹、安田由華、山森英長、梅田知美、藤本美智子、大井一高、石川充、赤松和土、岡野栄之、武田雅俊、橋本均
- Organizer
  第24回日本臨床精神神経薬理学会第44回日本神経精神薬理学会合同年会
- Place of Presentation
  名古屋
- Year and Date
  2014-11-20 – 2014-11-22
- Data Source
  KAKENHI-PROJECT-26860055
[Presentation] ヒストン脱アセチル化酵素阻害薬の持続処置が縫線核セロトニン神経に与える影響
- Author(s)
  浅岡希美、永安一樹、西谷直也、山城茉弓、白川久志、中川貴之、金子周司
- Organizer
  第24回日本臨床精神神経薬理学会第44回日本神経精神薬理学会合同年会
- Place of Presentation
  名古屋
- Year and Date
  2014-11-20 – 2014-11-22
- Data Source
  KAKENHI-PROJECT-26860055
[Presentation] 自閉スペクトラム症関連候補遺伝子のハイスループット機能評価系による解析
- Author(s)
  永安　一樹、松村　憲佑、中澤　敬信、安田　由華、山森　英長、梅田　知美、大井　一高、橋本　亮太、武田　雅俊、橋本　均
- Organizer
  2014年度包括脳ネットワーク冬のシンポジウム
- Place of Presentation
  東京
- Year and Date
  2014-12-12 – 2014-12-13
- Data Source
  KAKENHI-PROJECT-26670122
[Presentation] コルチコステロン誘発性うつ病モデルを用いたプロスタノイド受容体DP2を介する情動制御機構の解析
- Author(s)
  尾中勇祐、新谷紀人、木野村元彦、平井博之、長田欽也、中村正孝、早田敦子、笠井淳司、永安一樹、中澤敬信、馬場明道、橋本均
- Organizer
  生体機能と創薬シンポジウム2014
- Place of Presentation
  大阪
- Year and Date
  2014-08-28 – 2014-08-29
- Data Source
  KAKENHI-PROJECT-26860055
[Presentation] 脳内miRNA発現の高感度検出に向けたin situ hybridization法の最適化：炎症により発現変化する脳内miRNAの同定
- Author(s)
  柿原　素楽、笠井　淳司、岡田　遼、狭間　啓佑、中澤　敬信、永安　一樹、早田　敦子、新谷　紀人、橋本　均
- Organizer
  生体機能と創薬シンポジウム2014
- Place of Presentation
  大阪
- Year and Date
  2014-08-28 – 2014-08-29
- Data Source
  KAKENHI-PROJECT-26670122
[Presentation] ケタミンは縫線核AMPA受容体およびニコチン性アセチルコリン受容体を介して前頭前皮質5-HT遊離を引き起こす
- Author(s)
  西谷直也、永安一樹、浅岡希美、山城茉弓、白川久志、中川貴之、金子周司
- Organizer
  第24回日本臨床精神神経薬理学会第44回日本神経精神薬理学会合同年会
- Place of Presentation
  名古屋
- Year and Date
  2014-11-20 – 2014-11-22
- Data Source
  KAKENHI-PROJECT-26860055
[Presentation] iPS細胞関連技術を用いた統合失調症研究
- Author(s)
  中澤　敬信、橋本　亮太、永安　一樹、安田　由華、山森　英長、梅田　知美、藤本　美智子、大井　一高、石川　充、赤松　和土、岡野　栄之、武田　雅俊、橋本　均
- Organizer
  第24回日本臨床精神神経薬理学会第44回日本神経精神薬理学会合同年会
- Place of Presentation
  名古屋
- Year and Date
  2014-11-20 – 2014-11-22
- Invited
- Data Source
  KAKENHI-PROJECT-26670122
[Presentation] 脳内miRNA発現の高感度検出に向けたin situ hybridization法の最適化：炎症により発現変化する脳内miRNAの同定
- Author(s)
  柿原素楽, 笠井淳司, 岡田遼, 狭間啓佑, 中澤敬信, 永安一樹, 早田敦子, 新谷紀人, 橋本均
- Organizer
  生体機能と創薬シンポジウム2014
- Place of Presentation
  大阪
- Year and Date
  2014-08-28 – 2014-08-29
- Data Source
  KAKENHI-PROJECT-26860055
[Presentation] 神経ペプチドPACAPによる精神機能調節：創薬への展望
- Author(s)
  橋本均、新谷紀人、早田敦子、笠井淳司、永安一樹、中澤敬信
- Organizer
  第36回日本生物学的精神医学会第57回日本神経化学会大会合同年会
- Place of Presentation
  奈良
- Year and Date
  2014-09-29 – 2014-10-01
- Data Source
  KAKENHI-PROJECT-26860055

1. Kaneko Shuji (60177516)

# of Collaborated Projects: 4 results

# of Collaborated Products: 43 results
2. YASUDA Masaharu (90744110)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. 白川久志 (50402798)

# of Collaborated Projects: 3 results

# of Collaborated Products: 22 results
4. NAKAMURA Kae (40454607)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 山中航 (40551479)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. Hashimoto Hitoshi (30240849)

# of Collaborated Projects: 1 results

# of Collaborated Products: 17 results
7. 宗可奈子 (50816684)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 浅井聰 (80231108)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 浅岡希美 (90826091)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. 川合謙介 (70260924)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 石井宏憲 (30636676)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 上田康雅 (60332954)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 栗川知己 (20741333)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 三代憲司 (60776079)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 鶴岡典子 (70757632)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. Nakagawa Takayuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 16 results
17. NAKAZAWA Takanobu

# of Collaborated Projects: 0 results

# of Collaborated Products: 8 results
18. INOUE Ken-ichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. NAKAGAWA Shunsaku

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
20. MORI Yasuo

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
21. IMAI Satoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. YASUDA Yuka

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. YAMAMORI Hidenaga

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. TSUKAHARA Tamotsu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. OHMURA Yu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 金田勝幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
27. 小出剛

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 高橋阿貴

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 荻原孝史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 高野敦子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 橋本亮太

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
32. 西谷直也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 藤本美智子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 藤野陽生

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 小林克典

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. 谷池雅子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
37. 片山統裕

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. 山森哲雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. 松崎政紀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. 阿部修

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
41. 森寿

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
42. 青木茂樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
43. 饗場篤

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
44. 植田弘師

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nagayasu Kazuki 永安 一樹

Research Projects

Research Products

Co-Researchers

ストレス抵抗性と抗うつ薬慢性作用に共通する神経機構の解明とその創薬展開Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

脳室投射セロトニン神経の共遊離ペプチド同定とうつ病のバイオマーカー確立への挑戦Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of determinants of depression pathogenesis and treatmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

低分子から中分子に至るあらゆる化学構造のヒト作用予測モデルの開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of antidepressive serotonin projection as a possible target of cell transplantation therapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Genetic tools for circuit-based drug discoveryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on mental disorder using patient-specific iPS cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Nagayasu Kazuki 永安一樹