Kishikawa Takahiro 岸川孝弘

Researcher Number	00724171
Other IDs
Affiliation (Current)	2025: 東京大学, 医学部附属病院, 助教
Affiliation (based on the past Project Information) *help	2025: 東京大学, 医学部附属病院, 助教 2021 – 2023: 東京大学, 医学部附属病院, 助教 2017 – 2018: 東京大学, 医学部附属病院, 登録研究員 2014 – 2016: 東京大学, 医学部附属病院, 特任臨床医
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related / Gastroenterology / Medium-sized Section 53:Organ-based internal medicine and related fields Except Principal Investigator Basic Section 53010:Gastroenterology-related
Keywords	Principal Investigator 膵癌 / マウスモデル / ノンコーディングRNA / 翻訳後修飾 / ユビキチン化酵素 / ユビキチン化 / 細胞外小胞 / 非コードRNA / 二重鎖RNA / 消化器内科 … More / トランスジェニックマウス / 反復配列ＲＮＡ / 反復配列RNA / 網羅的遺伝子解析 / DNAダメージ修復の解析 / トランスジェニックマウスの作成 / DNAダメージ修復機能の解析 / 次世代シークエンス変異解析 / 膵がん … More Except Principal Investigator 細胞外小胞 / 癌性腹水 / 膵癌 Less

膵癌悪性化に寄与する反復配列由来RNAの機能解析と制御法の開発Principal Investigator
- Principal Investigator
  
  岸川孝弘
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  The University of Tokyo
Chronological sampling and molecular analyses of the ascites from patients with pancreatic cancer
- Principal Investigator
  
  高原楠昊
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  The University of Tokyo
Molecular mechanisms of pancreatic cancer progression induced by structural alternation of nucleic acids.Principal Investigator
- Principal Investigator
  
  岸川孝弘
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  The University of Tokyo
Molecular functions of pancreatic oncogenesis induced by dysregulation of ubiquitin ligases.Principal Investigator
- Principal Investigator
  
  Kishikawa Takahiro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  The University of Tokyo
Elucidation of expression mechanism to regulate repetitive RNA which acceralates pancreatic carcinogenesisPrincipal Investigator
- Principal Investigator
  
  kishikawa takahiro
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo
Molecular function of repetitive RNA which accerelates pancreatic carcinogenesisPrincipal Investigator
- Principal Investigator
  
  Kishikawa Takahiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo

All 2024 2023 2022 2021 2019 2018 2017 2016 2015 2014

All Journal Article Presentation

[Journal Article] Increased expression of TNFRSF14 and LIGHT in biliary epithelial cells of patients with primary sclerosing cholangitis2024
- Author(s)
  Kanai S, Fujiwara H, Mizuno S, Kishikawa T, Nakatsuka T, Hamada T, Tanaka M, Arita J, Nakai Y, Isayama H, Kasuga M, Tateishi R, Tateishi K, Ushiku T, Hasegawa K, Koike K, Fujishiro M.
- Journal Title
  
  Dig Liver Dis .
  
  Volume: 56(2) Issue: 2 Pages: 305-311
- DOI
  10.1016/j.dld.2023.08.057
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K16012, KAKENHI-PROJECT-22K06976, KAKENHI-PROJECT-23K07412, KAKENHI-PROJECT-21H02893
[Journal Article] Gut Bacteria-derived Membrane Vesicles Induce Colonic Dysplasia by Inducing DNA Damage in Colon Epithelial Cells2024
- Author(s)
  Miyakawa Yu、Otsuka Motoyuki、Shibata Chikako、Seimiya Takahiro、Yamamoto Keisuke、Ishibashi Rei、Kishikawa Takahiro、Tanaka Eri、Isagawa Takayuki、Takeda Norihiko、Kamio Noriaki、Imai Kenichi、Fujishiro Mitsuhiro
- Journal Title
  
  Cellular and Molecular Gastroenterology and Hepatology
  
  Volume: 17 Issue: 5 Pages: 745-767
- DOI
  10.1016/j.jcmgh.2024.01.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19517, KAKENHI-PROJECT-22K08110, KAKENHI-PROJECT-21K15916, KAKENHI-PROJECT-21H02893, KAKENHI-PROJECT-23K24090
[Journal Article] Satellite double-stranded RNA induces mesenchymal transition in pancreatic cancer by regulating alternative splicing2024
- Author(s)
  Iwata Takuma、Kishikawa Takahiro、Seimiya Takahiro、Notoya Genso、Suzuki Tatsunori、Shibata Chikako、Miyakawa Yu、Odawara Nariaki、Funato Kazuyoshi、Tanaka Eri、Yamagami Mari、Sekiba Kazuma、Otsuka Motoyuki、Koike Kazuhiko、Fujishiro Mitsuhiro
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 300 Issue: 3 Pages: 105742-105742
- DOI
  10.1016/j.jbc.2024.105742
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19517, KAKENHI-PROJECT-23K15033, KAKENHI-PROJECT-23K15065, KAKENHI-PROJECT-23K07392, KAKENHI-PROJECT-21K15368, KAKENHI-PROJECT-21H02893, KAKENHI-PROJECT-23K24090
[Journal Article] Cabozantinib inhibits HBV-RNA transcription by decreasing STAT3 binding to the enhancer region of cccDNA2023
- Author(s)
  Funato Kazuyoshi、Miyake Nozomi、Sekiba Kazuma、Miyakawa Yu、Seimiya Takahiro、Shibata Chikako、Kishikawa Takahiro、Otsuka Motoyuki
- Journal Title
  
  Hepatology Communications
  
  Volume: 7 Issue: 11
- DOI
  10.1097/hc9.0000000000000313
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19517, KAKENHI-PROJECT-23K15033, KAKENHI-PROJECT-21H02893
[Journal Article] Combination of serum human satellite RNA and miR-21-5p levels as a biomarker for pancreatic cancer2023
- Author(s)
  Seimiya Takahiro、Suzuki Tatsunori、Iwata Takuma、Kishikawa Takahiro、Sekiba Kazuma、Shibata Chikako、Ishigaki Kazunaga、Fujiwara Hiroaki、Oyama Hiroki、Kanai Sachiko、Sato Tatsuya、Nakai Yousuke、Ishibashi Rei、Moriyama Masaru、Nakagawa Ryo、Ijichi Hideaki、Otsuka Motoyuki、Koike Kazuhiko
- Journal Title
  
  iScience
  
  Volume: 26 Issue: 2 Pages: 106021-106021
- DOI
  10.1016/j.isci.2023.106021
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19517, KAKENHI-PROJECT-22K15390, KAKENHI-PROJECT-21H02893, KAKENHI-PROJECT-20J20625, KAKENHI-PROJECT-22K15958, KAKENHI-PROJECT-21K15368, KAKENHI-PROJECT-21K15916, KAKENHI-PROJECT-23K24090
[Journal Article] Extracellular vesicle mediated RNA editing may underlie the heterogeneity and spread of hepatocellular carcinoma in human tissue and in vitro2023
- Author(s)
  Shibata Chikako、Otsuka Motoyuki、Shimizu Takayuki、Seimiya Takahiro、Kishikawa Takahiro、Aoki Taku、Fujishiro Mitsuhiro
- Journal Title
  
  Oncology Reports
  
  Volume: 50 Issue: 5 Pages: 194-194
- DOI
  10.3892/or.2023.8631
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19517, KAKENHI-PROJECT-23K07392, KAKENHI-PROJECT-21H02893, KAKENHI-PROJECT-23K24090
[Journal Article] Smaller extracellular vesicles are released from pancreatic cancer cells by the alteration of the lipid composition under low glucose conditions2022
- Author(s)
  Shibata Chikako、Otsuka Motoyuki、Seimiya Takahiro、Ishigaki Kazunaga、Miyakawa Yu、Kishikawa Takahiro、Fujishiro Mitsuhiro
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 637 Pages: 314-321
- DOI
  10.1016/j.bbrc.2022.11.040
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19517, KAKENHI-PROJECT-22K15390, KAKENHI-PROJECT-22K15958, KAKENHI-PROJECT-21H02893, KAKENHI-PROJECT-20J20625, KAKENHI-PROJECT-23K24090
[Journal Article] HNF1B‐driven three‐dimensional chromatin structure for molecular classification in pancreatic cancers2022
- Author(s)
  Kato Hiroyuki、Tateishi Keisuke、Iwadate Dosuke、Yamamoto Keisuke、Fujiwara Hiroaki、Nakatsuka Takuma、Kudo Yotaro、Hayakawa Yoku、Ijichi Hideaki、Otsuka Motoyuki、Kishikawa Takahiro、Takahashi Ryota、Miyabayashi Koji、Nakai Yousuke、Hirata Yoshihiro、Toyoda Atsushi、Morishita Shinichi、Fujishiro Mitsuhiro
- Journal Title
  
  Cancer Science
  
  Volume: 114 Issue: 4 Pages: 1672-1685
- DOI
  10.1111/cas.15690
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19517, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-21H02893, KAKENHI-PROJECT-21K15966, KAKENHI-PROJECT-23K07350, KAKENHI-PROJECT-21K07886, KAKENHI-PROJECT-21K07907, KAKENHI-PROJECT-23K24314
[Journal Article] Lipolysis by pancreatic cancer‐derived extracellular vesicles in cancer‐associated cachexia via specific integrins2022
- Author(s)
  Shibata Chikako、Otsuka Motoyuki、Seimiya Takahiro、Kishikawa Takahiro、Ishigaki Kazunaga、Fujishiro Mitsuhiro
- Journal Title
  
  Clinical and Translational Medicine
  
  Volume: 12 Issue: 11 Pages: 1089-1089
- DOI
  10.1002/ctm2.1089
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19517, KAKENHI-PROJECT-22K15390, KAKENHI-PROJECT-22K15958, KAKENHI-PROJECT-21H02893, KAKENHI-PROJECT-20J20625, KAKENHI-PROJECT-23K24090
[Journal Article] WWP1 inactivation enhances efficacy of PI3K inhibitors while suppressing their toxicities in breast cancer models2021
- Author(s)
  Kishikawa Takahiro、Higuchi Hiroshi、Wang Limei、Panch Nivedita、Maymi Valerie、Best Sachem、Lee Samuel、Notoya Genso、Toker Alex、Matesic Lydia E.、Wulf Gerburg M.、Wei Wenyi、Otsuka Motoyuki、Koike Kazuhiko、Clohessy John G.、Lee Yu-Ru、Pandolfi Pier Paolo
- Journal Title
  
  Journal of Clinical Investigation
  
  Volume: 131 Issue: 24
- DOI
  10.1172/jci140436
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02893
[Journal Article] Mutant KRAS drives metabolic reprogramming and autophagic flux in premalignant pancreatic cells.2021
- Author(s)
  Suzuki T, Kishikawa T, Sato T, Takeda N, Sugiura Y, Seimiya T, Sekiba K, Ohno M, Iwata T, Ishibashi R, Otsuka M, Koike K.
- Journal Title
  
  Cancer Gene Ther.
  
  Volume: - Issue: 5 Pages: 505-518
- DOI
  10.1038/s41417-021-00326-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03430, KAKENHI-PROJECT-21K15368, KAKENHI-PROJECT-21K15916, KAKENHI-PROJECT-21H02893
[Journal Article] Pevonedistat, a Neuronal Precursor Cell-Expressed Developmentally Down-Regulated Protein 8-Activating Enzyme Inhibitor, Is a Potent Inhibitor of Hepatitis B Virus2019
- Author(s)
  Sekiba Kazuma、Otsuka Motoyuki、Ohno Motoko、Yamagami Mari、Kishikawa Takahiro、Seimiya Takahiro、Suzuki Tatsunori、Tanaka Eri、Ishibashi Rei、Funato Kazuyoshi、Koike Kazuhiko
- Journal Title
  
  Hepatology
  
  Volume: in press Issue: 5 Pages: 1903-1915
- DOI
  10.1002/hep.30491
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-18H05024, KAKENHI-PROJECT-16H05149, KAKENHI-PROJECT-17K15923, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-19H03430
[Journal Article] Inhibition of HBV Transcription From cccDNA With Nitazoxanide by Targeting the HBx?DDB1 Interaction2019
- Author(s)
  Sekiba Kazuma、Otsuka Motoyuki、Ohno Motoko、Yamagami Mari、Kishikawa Takahiro、Suzuki Tatsunori、Ishibashi Rei、Seimiya Takahiro、Tanaka Eri、Koike Kazuhiko
- Journal Title
  
  Cellular and Molecular Gastroenterology and Hepatology
  
  Volume: 7 Issue: 2 Pages: 297-312
- DOI
  10.1016/j.jcmgh.2018.10.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09405, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05024, KAKENHI-PROJECT-16H05149, KAKENHI-PROJECT-16KT0109, KAKENHI-PROJECT-16K09344, KAKENHI-PROJECT-17K15923, KAKENHI-PROJECT-19H03430
[Journal Article] Satellite RNA Increases DNA Damage and Accelerates Tumor Formation in Mouse Models of Pancreatic Cancer2018
- Author(s)
  Kishikawa Takahiro、Otsuka Motoyuki、Suzuki Tatsunori、Seimiya Takahiro、Sekiba Kazuma、Ishibashi Rei、Tanaka Eri、Ohno Motoko、Yamagami Mari、Koike Kazuhiko
- Journal Title
  
  Molecular Cancer Research
  
  Volume: 16 Issue: 8 Pages: 1255-1262
- DOI
  10.1158/1541-7786.mcr-18-0139
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-16KT0109, KAKENHI-PROJECT-16K09344, KAKENHI-PROJECT-17K15923
[Journal Article] ISGF3 with reduced phosphorylation is associated with constitutive expression of interferon-induced genes in aging cells2018
- Author(s)
  Yamagami Mari、Otsuka Motoyuki、Kishikawa Takahiro、Sekiba Kazuma、Seimiya Takahiro、Tanaka Eri、Suzuki Tatsunori、Ishibashi Rei、Ohno Motoko、Koike Kazuhiko
- Journal Title
  
  npj Aging and Mechanisms of Disease
  
  Volume: 4 Issue: 1 Pages: 11-11
- DOI
  10.1038/s41514-018-0030-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09405, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-16H05149, KAKENHI-PROJECT-16KT0109, KAKENHI-PROJECT-17K15923
[Journal Article] DHX9 regulates production of hepatitis B virus-derived circular RNA and viral protein levels2018
- Author(s)
  Sekiba Kazuma、Otsuka Motoyuki、Ohno Motoko、Kishikawa Takahiro、Yamagami Mari、Suzuki Tatsunori、Ishibashi Rei、Seimiya Takahiro、Tanaka Eri、Koike Kazuhiko
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 30 Pages: 20953-20964
- DOI
  10.18632/oncotarget.25104
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-16KT0109, KAKENHI-PROJECT-17K15923
[Journal Article] Repression of miRNA function mediates inflammation-associated colon tumorigenesis.2017
- Author(s)
  Yoshikawa T., J. F. Wu, M. Otsuka, T. Kishikawa, N. Suzuki, A. Takata, M. Ohno, R. Ishibashi, M. Yamagami, R. Nakagawa, N. Kato, M. Miyazawa, J. Han, and K. Koike
- Journal Title
  
  Gastroenterology
  
  Volume: 152 Issue: 3 Pages: 631-643
- DOI
  10.1053/j.gastro.2016.10.043
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01268, KAKENHI-PROJECT-16H05199, KAKENHI-PROJECT-26860492, KAKENHI-PROJECT-16K19329, KAKENHI-PROJECT-16KT0109, KAKENHI-PROJECT-16K09344, KAKENHI-PROJECT-16H05149, KAKENHI-PROJECT-15K09038
[Journal Article] RASAL1 is a potent regulator of hepatic stellate cell activity and liver fibrosis2017
- Author(s)
  Takata Akemi、Otsuka Motoyuki、Kishikawa Takahiro、Yamagami Mari、Ishibashi Rei、Sekiba Kazuma、Suzuki Tatsunori、Ohno Motoko、Yamashita Yui、Abe Takaya、Masuzaki Ryota、Ikenoue Tsuneo、Koike Kazuhiko
- Journal Title
  
  Oncotarget
  
  Volume: 8 Issue: 39 Pages: 64840-64852
- DOI
  10.18632/oncotarget.17609
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16KT0109, KAKENHI-PROJECT-16K09344, KAKENHI-PROJECT-17K15923, KAKENHI-PROJECT-15H04807, KAKENHI-PROJECT-16H05149
[Journal Article] Transcriptional activation of the MICA gene with an engineered CRISPR-Cas9 system2017
- Author(s)
  Sekiba K, Yamagami M, Otsuka M, Suzuki T, Kishikawa T, Ishibashi R, Ohno M, Sato M, Koike K
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: - Issue: 2 Pages: 521-525
- DOI
  10.1016/j.bbrc.2017.03.076
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04807, KAKENHI-PROJECT-26460984, KAKENHI-PROJECT-16KT0109, KAKENHI-PROJECT-17K09405, KAKENHI-PROJECT-17K15923, KAKENHI-PROJECT-16H05149
[Journal Article] Quantitation of circulating satellite RNAs in pancreatic cancer patients.2016
- Author(s)
  Kishikawa T, Otsuka M, Yoshikawa T, Ohno M, Yamamoto K, Yamamoto N, Kotani A, and Koike K
- Journal Title
  
  JCI Insight
  
  Volume: 1
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26860492
[Journal Article] Satellite RNAs promote pancreatic oncogenic process via the dysfunction of YBX1.2016
- Author(s)
  Kishikawa T, Otsuka M, Yoshikawa T, Ohno M, Ijichi H, and Koike K
- Journal Title
  
  Nature Communications
  
  Volume: 7 Issue: 1 Pages: 13006-13006
- DOI
  10.1038/ncomms13006
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26860492, KAKENHI-PROJECT-16KT0109
[Journal Article] Mutual antagonism between hepatitis B viral mRNA and host microRNA let-7.2016
- Author(s)
  Takata A, Otsuka M, Ohno M, Kishikawa T, Yoshikawa T, Koike K.
- Journal Title
  
  Sci Rep.
  
  Volume: 6 Issue: 1 Pages: 23237-23237
- DOI
  10.1038/srep23237
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293076, KAKENHI-PROJECT-15H04807, KAKENHI-PROJECT-26860492
[Journal Article] Diagnostic and therapeutic application of noncoding RNAs for hepatocellular carcinoma.2015
- Author(s)
  Shibata C, Otsuka M, Kishikawa T, Ohno M, Yoshikawa T, Takata A, Koike K.
- Journal Title
  
  World J Hepatol.
  
  Volume: 27 Issue: 1 Pages: 1-6
- DOI
  10.4254/wjh.v7.i1.1
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25293076, KAKENHI-PROJECT-25460979, KAKENHI-PROJECT-26860492
[Journal Article] Circulating RNAs as new biomarkers for detecting pancreatic cancer2015
- Author(s)
  Kishikawa, T. Otsuka, M. Ohno, M. Yoshikawa, T. Takata, A. Koike, K.
- Journal Title
  
  World J Gastroenterol
  
  Volume: 21(28) Issue: 28 Pages: 8527-8540
- DOI
  10.3748/wjg.v21.i28.8527
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860492
[Journal Article] Decreased miR122 in hepatocellular carcinoma leads to chemoresistance with increased arginine2015
- Author(s)
  Kishikawa, T. Otsuka, M. Tan, P. S. Ohno, M. Sun, X. Yoshikawa, T. Shibata, C. Takata, A. Kojima, K. Takehana, K. Ohishi, M. Ota, S. Noyama, T. Kondo, Y. Sato, M. Soga, T. Hoshida, Y. Koike, K.
- Journal Title
  
  Oncotarget
  
  Volume: 6 Pages: 8339-52
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860492
[Journal Article] Development of a　screening method to identify regulators of MICA shedding.2015
- Author(s)
  Kishikawa T, Otsuka M, Ohno M, Yoshikawa T, Sato M, Koike K.
- Journal Title
  
  Biochem Biophys Res　Commun.
  
  Volume: 465 Issue: 4 Pages: 764-768
- DOI
  10.1016/j.bbrc.2015.08.081
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460984, KAKENHI-PROJECT-26860492, KAKENHI-PROJECT-25293076
[Journal Article] ROCK inhibition enhances microRNA function by promoting deadenylation of targeted mRNAs via increasing PAIP2 expression2015
- Author(s)
  Yoshikawa, T. Wu, J. Otsuka, M. Kishikawa, T. Ohno, M. Shibata, C. Takata, A. Han, F. Kang, Y. J. Chen, C. A. Shyu, A. B. Han, J. Koike, K
- Journal Title
  
  Nucleic Acids Res
  
  Volume: 43(15) Issue: 15 Pages: 7577-89
- DOI
  10.1093/nar/gkv728
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860492, KAKENHI-PROJECT-15H04807, KAKENHI-PROJECT-25860520, KAKENHI-PROJECT-25293076
[Journal Article] Specific delivery of microRNA93 into HBV-replicating hepatocytes downregulates protein expression of liver cancer susceptible gene MICA2014
- Author(s)
  Ohno M, Otsuka M, Kishikawa T, Shibata C, Yoshikawa T, Takata A, Muroyama R, Kowatari N, Sato M, Kato N, Kuroda S, Koike K
- Journal Title
  
  Oncotarget
  
  Volume: 30 Pages: 5581-90
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26860492
[Journal Article] The role of microRNAs in hepatocarcinogenesis: current knowledge and future prospects.2014
- Author(s)
  Otsuka M, Kishikawa T, Yoshikawa T, Ohno M, Takata A, Shibata C, Koike K.
- Journal Title
  
  J Gastroenterol.
  
  Volume: 49 Issue: 2 Pages: 173-84
- DOI
  10.1007/s00535-013-0909-8
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25293076, KAKENHI-PROJECT-25860520, KAKENHI-PROJECT-26460984, KAKENHI-PROJECT-26860492
[Presentation] 1.Double-stranded RNA derived from tandem repeat sequences induces mesenchymal transition in pancreatic cancer cells by regulating alternative splicing.2023
- Author(s)
  Takahiro Kishikawa, Takuma Iwata, Takahiro Seimiya, Genso Notoya, Tatsunori Suzuki, Chikako Shibata, Kazuhiko Koike, Motoyuki Otsuka, and Mitsuhiro Fujishiro
- Organizer
  AACR Special Conference in Cancer Research: Pancreatic Cancer
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02893
[Presentation] 1.Double-stranded RNA derived from tandem repeat sequences induces mesenchymal transition in pancreatic cancer cells by regulating alternative splicing.2023
- Author(s)
  Takahiro Kishikawa, Takuma Iwata, Takahiro Seimiya, Genso Notoya, Tatsunori Suzuki, Chikako Shibata, Kazuhiko Koike, Motoyuki Otsuka, and Mitsuhiro Fujishiro
- Organizer
  AACR Special Conference in Cancer Research: Pancreatic Cancer
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19517
[Presentation] 3.Establishment of highly sensitive method of repetitive RNAs in the serum as an early detecting marker of pancreatic cancer2017
- Author(s)
  Takahiro Kishikawa
- Organizer
  Fourth Annual US Japan Workshop on Cancer Biomarkers in Collaboration with NCI Early Detection Research Network
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15923
[Presentation] High sensitive detecting procedure of circulating repetitive RNA as a novel early marker of pancreatic cancer.2017
- Author(s)
  Kishikawa T. Otsuka M. Ohono M. Yamagami M. Ishibashi R. Sekiba K. Suzuki T. Koike K
- Organizer
  AACR annual meeting 2017
- Place of Presentation
  Washinton DC(USA)
- Year and Date
  2017-04-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860492
[Presentation] 1.膵がんの早期発見を可能にする血清中の反復配列RNAの高感度検出法の開発2017
- Author(s)
  岸川孝弘大塚基之吉川剛史大野元子山上まり石橋嶺関場一磨鈴木辰典小池和彦
- Organizer
  第54回日本臨床分子医学会学術集会
- Data Source
  KAKENHI-PROJECT-17K15923
[Presentation] 膵がんの早期発見を可能にする血清中の反復配列RNAの高感度検出法の開発2017
- Author(s)
  岸川孝弘　大塚基之　大野元子　山上まり　石橋嶺　關場一磨　鈴木辰典　小池和彦
- Organizer
  第54回日本臨床分子医学会学術総会
- Place of Presentation
  東京国際フォーラム(東京)
- Year and Date
  2017-04-14
- Data Source
  KAKENHI-PROJECT-26860492
[Presentation] 2.High sensitive detecting procedure of circulating repetitive RNA as a novel early marker of pancreatic cancer2017
- Author(s)
  Takahiro Kishikawa, Motoyuki Otsuka, Takeshi Yoshikawa, Motoko Ohno, Mari Yamagami, Rei Ishibashi, Kazuma Sekiba, Tatsunori Suzuki, and Kazuhiko Koike
- Organizer
  AACR annual meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15923
[Presentation] 反復配列RNAの異常発現が膵発癌を促進する分子生物学的機構の解明2016
- Author(s)
  岸川孝弘　大塚基之　吉川剛史　大野元子　伊地知秀明　小池和彦
- Organizer
  G-plus
- Place of Presentation
  ホテルイースト東京21Aホール(東京)
- Year and Date
  2016-12-17
- Data Source
  KAKENHI-PROJECT-26860492
[Presentation] Deregulated transcription of mouse satellite sequences accelerates oncogenic processes via functional inhibition of YBX1 protein2016
- Author(s)
  Kishikawa, T. Otsuka, M. Ohno, M. Yoshikawa, T. Koike, K.
- Organizer
  AACR annual meeting 2016
- Place of Presentation
  New Orleans
- Year and Date
  2016-04-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860492
[Presentation] Deregulated transcription of mouse satellite sequences accelerates oncogenic processes via functional inhibition of YBX1 protein2016
- Author(s)
  Kishikawa T. Otsuka M. Yoshikawa T. Ohono M. Koike K
- Organizer
  AACR annual meeting 2016
- Place of Presentation
  New Orleans(USA)
- Year and Date
  2016-04-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860492
[Presentation] 酸化ストレスを介した膵発癌プロセスを加速させるノンコーディングサテライトRNAの異常発現2015
- Author(s)
  岸川孝弘　大塚基之　小池和彦
- Organizer
  第101回　日本消化器病学会総会
- Place of Presentation
  仙台
- Year and Date
  2015-04-22
- Data Source
  KAKENHI-PROJECT-26860492
[Presentation] Alternation in microRNA expression profile in the process of pancreatic carcinogenesis2015
- Author(s)
  Kishikawa, T. Otsuka, M. Ohno, M. Yoshikawa, T. Koike, K.
- Organizer
  AACR annual meeting 2015
- Place of Presentation
  Phiradelphia
- Year and Date
  2015-04-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860492
[Presentation] Detection of human satellite RNA in the serum of high-risk patients of pancreatic cancer2014
- Author(s)
  Takahiro Kishikawa, Motoyuki Otsuka, Takeshi Yoshikawa, Motoko Ohno, Kazuhiko Koike
- Organizer
  AACR annual meeting 2014
- Place of Presentation
  San Diego
- Year and Date
  2014-04-06
- Data Source
  KAKENHI-PROJECT-26860492

1. 高原楠昊 (10750622)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 大塚基之

# of Collaborated Projects: 0 results

# of Collaborated Products: 9 results
3. 宮澤正顕

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 藤原弘明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 佐藤雅哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 小池和彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kishikawa Takahiro 岸川 孝弘

Research Projects

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Co-Researchers

膵癌悪性化に寄与する反復配列由来RNAの機能解析と制御法の開発Principal Investigator

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Chronological sampling and molecular analyses of the ascites from patients with pancreatic cancer

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Molecular mechanisms of pancreatic cancer progression induced by structural alternation of nucleic acids.Principal Investigator

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Molecular functions of pancreatic oncogenesis induced by dysregulation of ubiquitin ligases.Principal Investigator

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Elucidation of expression mechanism to regulate repetitive RNA which acceralates pancreatic carcinogenesisPrincipal Investigator

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Molecular function of repetitive RNA which accerelates pancreatic carcinogenesisPrincipal Investigator

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[Journal Article] Increased expression of TNFRSF14 and LIGHT in biliary epithelial cells of patients with primary sclerosing cholangitis2024

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[Journal Article] Gut Bacteria-derived Membrane Vesicles Induce Colonic Dysplasia by Inducing DNA Damage in Colon Epithelial Cells2024

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[Journal Article] Satellite double-stranded RNA induces mesenchymal transition in pancreatic cancer by regulating alternative splicing2024

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[Journal Article] Cabozantinib inhibits HBV-RNA transcription by decreasing STAT3 binding to the enhancer region of cccDNA2023

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[Journal Article] Combination of serum human satellite RNA and miR-21-5p levels as a biomarker for pancreatic cancer2023

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[Journal Article] Extracellular vesicle mediated RNA editing may underlie the heterogeneity and spread of hepatocellular carcinoma in human tissue and in vitro2023

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[Journal Article] Smaller extracellular vesicles are released from pancreatic cancer cells by the alteration of the lipid composition under low glucose conditions2022

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[Journal Article] HNF1B‐driven three‐dimensional chromatin structure for molecular classification in pancreatic cancers2022

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Kishikawa Takahiro 岸川孝弘