Mimura Imari 三村維真理

… Alternative Names

MIMURA IMARI 三村維真理

Less

Researcher Number	00727084
Affiliation (Current)	2025: 東京大学, 医学部附属病院, 助教
Affiliation (based on the past Project Information) *help	2023 – 2025: 東京大学, 医学部附属病院, 助教 2023: 東京大学, 医学部附属病院, 特任講師 2022: 東京大学, 医学部附属病院, 特任講師(病院) 2015 – 2021: 東京大学, 医学部附属病院, 助教 2014: 東京大学, 先端科学技術研究センター, 研究員
Review Section/Research Field	Principal Investigator Basic Section 53040:Nephrology-related / Kidney internal medicine Except Principal Investigator Basic Section 53040:Nephrology-related / Kidney internal medicine
Keywords	Principal Investigator 腎線維化 / ヒストン / 線維化 / 慢性腎不全 / ヒストン修飾 / 低酸素 / 慢性腎臓病 / 尿細管間質 / non-coding RNA / 腎尿細管間質 / 非翻訳RNA / ヒストン修飾酵素阻害薬 / エピジェネティクス … More Except Principal Investigator … More HIF / 慢性腎臓病 / 低酸素 / エピゲノム / 糖尿病関連腎臓病 / CKD / ミトコンドリア / エピジェネティック / 線維化 / エピジェネティックス / 低酸素応答 / エピジェネティクス / エネルギー代謝 / 腎不全 / ＨＩＦ Less

急性腎障害から低酸素メモリーを介した慢性腎臓病発症機序の解明Principal Investigator
- Principal Investigator
  
  三村維真理
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  The University of Tokyo
HIFの活性化の腎臓における細胞特異的影響の解明
- Principal Investigator
  
  南学正臣
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  The University of Tokyo
ヒストン修飾阻害薬GSKJ4による腎尿細管間質線維化の病態解明Principal Investigator
- Principal Investigator
  
  三村維真理
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  The University of Tokyo
Elucidation of metabolic reprogramming in the kidney and development of novel therapeutic approaches utilizing HIF against kidney disease
- Principal Investigator
  
  Nangaku Masaomi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  The University of Tokyo
Functional analysis of novel microRNA inhibiting tubulointerstitial fibrosis.Principal Investigator
- Principal Investigator
  
  Mimura Imari
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokyo
Metabolic Reprogramming and Hypoxic Memory in Kidney Disease
- Principal Investigator
  
  Nangaku Masaomi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokyo
Analysis of novel transcriptional mechanisms and identification of non-coding RNAs contributing renal fibrosis.Principal Investigator
- Principal Investigator
  
  MIMURA IMARI
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokyo

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014

All Journal Article Presentation Book

[Book] Biomarkers in Diseases.: Methods, Discoveries and Applications. Biomarkers in Kidney Disease.2015
- Author(s)
  Imari Mimura, Masaomi Nangaku
- Total Pages
  21
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-26860627
[Book] 日本腎臓学会雑誌2015
- Author(s)
  三村　維真理
- Total Pages
  7
- Publisher
  日本腎臓学会
- Data Source
  KAKENHI-PROJECT-26860627
[Book] 医学のあゆみ2014
- Author(s)
  三村　維真理、田中　哲洋
- Total Pages
  6
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-26860627
[Journal Article] Epigenetic roles in clonal hematopoiesis and aging kidney-related chronic kidney disease2023
- Author(s)
  Ogura Yoshiyasu、Mimura Imari
- Journal Title
  
  Frontiers in Cell and Developmental Biology
  
  Volume: 11
- DOI
  10.3389/fcell.2023.1281850
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08604
[Journal Article] Chromatin remodeling factor, INO80, inhibits PMAIP1 in renal tubular cells via exchange of histone variant H2A.Z. for H2A2023
- Author(s)
  Miura Rika、Mimura Imari、Saigusa Hanako、Yamazaki Tomotaka、Tanemoto Fumiaki、Kurata Yu、Sato Dai、Tanaka Tetsuhiro、Nangaku Masaomi
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 13235-13235
- DOI
  10.1038/s41598-023-40540-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K15223, KAKENHI-PROJECT-20K08604, KAKENHI-PROJECT-23K07713, KAKENHI-PROJECT-23K27615
[Journal Article] Epigenetic regulation of angiogenesis and ischemic response by long noncoding RNA LEENE in diabetes2023
- Author(s)
  Mimura Imari、Nangaku Masaomi
- Journal Title
  
  Kidney International
  
  Volume: 104 Issue: 6 Pages: 1048-1050
- DOI
  10.1016/j.kint.2023.06.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08604
[Journal Article] ABCA1 deficiency contributes to podocyte pyroptosis priming via the APE1/IRF1 axis in diabetic kidney disease2023
- Author(s)
  Ito Marie、Ducasa Gloria Michelle、Molina Judith David、Santos Javier Varona、Mallela Shamroop Kumar、Kim Jin Ju、Ge Mengyuan、Mitrofanova Alla、Sloan Alexis、Merscher Sandra、Mimura Imari、Fornoni Alessia
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 9616-9616
- DOI
  10.1038/s41598-023-35499-5
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08604
[Journal Article] Hypoxia‐inducible lncRNA MIR210HG promotes HIF1α expression by inhibiting miR‐93‐5p in renal tubular cells2023
- Author(s)
  Saigusa Hanako、Mimura Imari、Kurata Yu、Tanaka Tetsuhiro、Nangaku Masaomi
- Journal Title
  
  The FEBS Journal
  
  Volume: 290 Issue: 16 Pages: 4040-4056
- DOI
  10.1111/febs.16794
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K15223, KAKENHI-PROJECT-20K08604, KAKENHI-PROJECT-23K07713, KAKENHI-PROJECT-23K27615
[Journal Article] Dznep, a histone modification inhibitor, inhibits HIF1α binding to TIMP2 gene and suppresses TIMP2 expression under hypoxia2023
- Author(s)
  Yamazaki Tomotaka、Mimura Imari、Kurata Yu、Tanaka Tetsuhiro、Nangaku Masaomi
- Journal Title
  
  Physiological Reports
  
  Volume: 11 Issue: 17
- DOI
  10.14814/phy2.15810
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K15223, KAKENHI-PROJECT-20K08604, KAKENHI-PROJECT-23K07713, KAKENHI-PROJECT-23K27615
[Journal Article] Therapies Targeting Epigenetic Alterations in Acute Kidney Injury-to-Chronic Kidney Disease Transition2022
- Author(s)
  Fumiaki Tanemoto, Imari Mimura
- Journal Title
  
  Pharmaceuticals
  
  Volume: 15 Issue: 2 Pages: 123-123
- DOI
  10.3390/ph15020123
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08604
[Journal Article] Epigenetic memory contributing to the pathogenesis of AKI-to-CKD transition2022
- Author(s)
  Fumiaki Tanemoto, Masaomi Nangaku, Imari Mimura
- Journal Title
  
  Frontiers in Molecular Biosciences
  
  Volume: 21 Pages: 1003227-1003227
- DOI
  10.3389/fmolb.2022.1003227
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08604
[Journal Article] Effect of M2-like macrophages of the injured-kidney cortex on kidney cancer progression2022
- Author(s)
  Taisuke Ishii, Imari Mimura, Koji Nagaoka, Akihiro Naito, Takehito Sugasawa, Ryohei Kuroda, Daisuke Yamada, Yasuharu Kanki, Haruki Kume, Tetsuo Ushiku, Kazuhiro Kakimi, Tetsuhiro Tanaka, Masaomi Nangaku
- Journal Title
  
  Cell Death Discovery
  
  Volume: 5 Issue: 1 Pages: 480-480
- DOI
  10.1038/s41420-022-01255-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08604, KAKENHI-PROJECT-20H03432, KAKENHI-PROJECT-20K08626, KAKENHI-PROJECT-20K09161
[Journal Article] Treatment of Diabetic Kidney Disease: Current and Future2021
- Author(s)
  Tomotaka Yamazaki, Imari Mimura, Tetsuhiro Tanaka, Masaomi Nangaku
- Journal Title
  
  Diabetes Metab J
  
  Volume: 1 Issue: 1 Pages: 11-26
- DOI
  10.4093/dmj.2020.0217
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08604, KAKENHI-PROJECT-20K08626, KAKENHI-PROJECT-21J10424
[Journal Article] Are women more susceptible to renal dysfunction?2019
- Author(s)
  Imari Mimura
- Journal Title
  
  Kidney International
  
  Volume: 96 Issue: 6 Pages: 1275-1277
- DOI
  10.1016/j.kint.2019.08.030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19477
[Journal Article] Nutcracker Syndrome with the Superimposition of Thin Basement Membrane Syndrome2019
- Author(s)
  Hirakawa Y, et al.
- Journal Title
  
  Intern. Med.
  
  Volume: 58 Issue: 3 Pages: 411-414
- DOI
  10.2169/internalmedicine.1433-18
- NAID
  130007585605
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2019-02-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08717, KAKENHI-PROJECT-16K19477
[Journal Article] The Lasker Prize award 2018: histones "tail" the story.2018
- Author(s)
  Mimura I, Nangaku M.
- Journal Title
  
  Kidney International
  
  Volume: 94 Issue: 6 Pages: 1032-1034
- DOI
  10.1016/j.kint.2018.10.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19477
[Journal Article] Intravital phosphorescence lifetime imaging of the renal cortex accurately measures renal hypoxia.2018
- Author(s)
  Hirakawa Y, Mizukami K, Yoshihara T, Takahashi I, Khulan P, Honda T, Mimura I, Tanaka T, Tobita S, Nangaku M.
- Journal Title
  
  Kidney Int.
  
  Volume: 印刷中 Issue: 6 Pages: 1483-1489
- DOI
  10.1016/j.kint.2018.01.015
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09688, KAKENHI-PROJECT-17K16070, KAKENHI-PROJECT-16K19477, KAKENHI-PLANNED-26111003, KAKENHI-PLANNED-26111012, KAKENHI-PROJECT-17H02078, KAKENHI-PROJECT-18H02824, KAKENHI-PROJECT-18H03509
[Journal Article] Genome-wide analysis revealed that DZNep reduces tubulointerstitial fibrosis via down-regulation of pro-fibrotic genes.2018
- Author(s)
  Mimura I, Hirakawa Y, Kanki Y, Nakaki R, Suzuki Y, Tanaka T, Aburatani H, Nangaku M.
- Journal Title
  
  Sci Rep.
  
  Volume: 28 Issue: 1 Pages: 3779-3779
- DOI
  10.1038/s41598-018-22180-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09688, KAKENHI-PROJECT-16K15438, KAKENHI-PROJECT-16K19477, KAKENHI-PROJECT-15H04835, KAKENHI-PROJECT-17H03614, KAKENHI-PROJECT-15KK0251, KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-18H02824, KAKENHI-PROJECT-16H06279
[Journal Article] Kidney aging: an irresistible slope.2018
- Author(s)
  Mimura I
- Journal Title
  
  Kidney International
  
  Volume: 95 Issue: 3 Pages: 492-494
- DOI
  10.1016/j.kint.2018.11.036
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19477
[Journal Article] Novel lnc RNA regulated by HIF-1 inhibits apoptotic cell death in the renal tubular epithelial cells under hypoxia.2017
- Author(s)
  Mimura I, Hirakawa Y, Kanki Y, Kushida N, Nakaki R, Suzuki Y, Tanaka T, Aburatani H, Nangaku M.
- Journal Title
  
  Physiol Rep.
  
  Volume: 5 Issue: 8 Pages: e13203-e13203
- DOI
  10.14814/phy2.13203
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09688, KAKENHI-PROJECT-16K15438, KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-15H04835, KAKENHI-PROJECT-17H03614, KAKENHI-PROJECT-15KK0251
[Journal Article] Epigenetic Changes in the Acute Kidney Injury-to-Chronic Kidney Disease Transition.2017
- Author(s)
  Nangaku M, Hirakawa Y, Mimura I, Inagi R, Tanaka T.
- Journal Title
  
  Nephron.
  
  Volume: 137 Issue: 4 Pages: 256-259
- DOI
  10.1159/000476078
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09688, KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-15H04835, KAKENHI-PROJECT-15K09247, KAKENHI-PROJECT-15KT0088, KAKENHI-PROJECT-16K15465
[Journal Article] New insights into molecular mechanisms of epigenetic regulation in kidney disease.2016
- Author(s)
  Mimura I, Tanaka T, Nangaku M.
- Journal Title
  
  Clin Exp Pharmacol Physiol
  
  Volume: 43 Issue: 12 Pages: 1159-1167
- DOI
  10.1111/1440-1681.12663
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-15H04835, KAKENHI-PROJECT-26461215, KAKENHI-PROJECT-15K09247
[Journal Article] Epigenetic memory in kidney diseases.2016
- Author(s)
  Mimura I.
- Journal Title
  
  Kidney International.
  
  Volume: 89 Issue: 2 Pages: 274-277
- DOI
  10.1016/j.kint.2015.12.026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26860627
[Journal Article] Hypoxia-Inducible Factor-1α Activates the Transforming Growth Factor-β/SMAD3 Pathway in Kidney Tubular Epithelial Cells.2016
- Author(s)
  Kushida N, Nomura S, Mimura I, Fujita T, Yamamoto S, Nangaku M, Aburatani H.
- Journal Title
  
  Am J Nephrol
  
  Volume: 44 Pages: 276-285
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04835
[Journal Article] Role of Uremic Toxins in Erythropoiesis-Stimulating Agent Resistance in Chronic Kidney Disease and Dialysis Patients.2015
- Author(s)
  Nangaku M, Mimura I, Yamaguchi J, Higashijima Y, Wada T, Tanaka T.
- Journal Title
  
  Journal of Renal Nutrition
  
  Volume: 25 Issue: 2 Pages: 160-163
- DOI
  10.1053/j.jrn.2014.10.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J08634, KAKENHI-PROJECT-14J03553, KAKENHI-PROJECT-24591189, KAKENHI-PROJECT-26461215, KAKENHI-PROJECT-26860627, KAKENHI-PROJECT-15K09247
[Journal Article] Quantitating intracellular oxygen tension in vivo by phosphorescence lifetime measurement2015
- Author(s)
  Hirakawa Y, Yoshihara T, Kamiya M, Mimura I, Fujikura D, Masuda T, Kikuchi R, Takahashi I, Urano Y, Tobita S, Nangaku M.
- Journal Title
  
  Sci Rep
  
  Volume: 5 Issue: 1 Pages: 17838-17838
- DOI
  10.1038/srep17838
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09247, KAKENHI-PLANNED-15H05951, KAKENHI-PLANNED-26111003, KAKENHI-PLANNED-26111012, KAKENHI-PROJECT-15H04835, KAKENHI-PROJECT-26670425, KAKENHI-PROJECT-26860627, KAKENHI-PROJECT-26702011
[Journal Article] Evolution of epigenetics in kidney diseases.2015
- Author(s)
  Mimura I.
- Journal Title
  
  Nihon Jinzo Gakkai Shi.
  
  Volume: 57 Pages: 241-247
- NAID
  40020351548
- Data Source
  KAKENHI-PROJECT-26860627
[Journal Article] Epigenetic Changes Induced by Hypoxia-Inducible Factor: a Long Way Still To Go as a Target for Therapy?2015
- Author(s)
  Nangaku M, Inagi R, Mimura I, Tanaka T.
- Journal Title
  
  Journal of American Society of Nephrology.
  
  Volume: 26 Pages: 1478-1480
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26860627
[Journal Article] How the Target Hemoglobin of Renal Anemia Should Be2015
- Author(s)
  Mimura I, Tanaka T, Nangaku M
- Journal Title
  
  Nephron
  
  Volume: 131 Issue: 3 Pages: 202-9
- DOI
  10.1159/000440849
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09247, KAKENHI-PROJECT-26461215, KAKENHI-PROJECT-26860627
[Journal Article] Endothelin-converting enzyme is a plausible target gene for hypoxia-inducible factor.2014
- Author(s)
  Khamaisi M, Toukan H, Axelrod JH, Rosenberger C, Skarzinski G, Shina A, Meidan R, Koesters R, Rosen S, Walkinshaw G, Mimura I, Nangaku M, Heyman SN.
- Journal Title
  
  Kidney International
  
  Volume: 87 Issue: 4 Pages: 761-770
- DOI
  10.1038/ki.2014.362
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J08634, KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-26860627
[Journal Article] Direct Evidence for Pitavastatin Induced Chromatin Structure Change in the KLF4 Gene in Endothelial Cells.2014
- Author(s)
  Maejima T, Inoue T, Kanki Y, Kohro T, Li G, Ohta Y, Kimura H, Kobayashi M, Taguchi A, Tsutsumi S, Iwanari H, Yamamoto S, Aruga H, Dong S, Stevens JF, Poh HM, Yamamoto K, Kawamura T, Mimura I,
- Journal Title
  
  PLoS One.
  
  Volume: 9 Issue: 5 Pages: e96005-e96005
- DOI
  10.1371/journal.pone.0096005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-12J08634, KAKENHI-PROJECT-22229009, KAKENHI-PROJECT-24500360, KAKENHI-PLANNED-25116005, KAKENHI-PUBLICLY-25118505, KAKENHI-PUBLICLY-25125707, KAKENHI-PROJECT-25670035, KAKENHI-PROJECT-25670619, KAKENHI-PROJECT-26250041, KAKENHI-PROJECT-26290035, KAKENHI-PROJECT-26430121, KAKENHI-PROJECT-26560395, KAKENHI-PROJECT-26640069, KAKENHI-PROJECT-26670397, KAKENHI-PROJECT-26710013, KAKENHI-PROJECT-26860627, KAKENHI-PUBLICLY-26116708
[Journal Article] Epigenetics in kidney diseases.2014
- Author(s)
  Mimura I, Nangaku M
- Journal Title
  
  Rinsho Byori
  
  Volume: 62 Pages: 180-189
- NAID
  40020017459
- Data Source
  KAKENHI-PROJECT-26860627
[Journal Article] Cross-enhancement of ANGPTL4 transcription by HIF1 alpha and PPAR beta/delta is the result of the conformational proximity of two response elements.2014
- Author(s)
  Inoue T, Kohro T, Tanaka T, Kanki Y, Li G, Poh HM, Mimura I, Kobayashi M, Taguchi A, Maejima T, Suehiro JI, Sugiyama A, Kaneki K, Aruga H, Dong S, Stevens JF, Yamamoto S, Tsutsumi S, Fujita T, Ruan X, Aburatani H, Nangaku M, Ruan Y, Kodama T, Wada Y.
- Journal Title
  
  Genome Biology
  
  Volume: 15 Issue: 4
- DOI
  10.1186/gb-2014-15-4-r63
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-12J08634, KAKENHI-PROJECT-24390213, KAKENHI-PUBLICLY-25118505, KAKENHI-PUBLICLY-25118709, KAKENHI-PUBLICLY-25125707, KAKENHI-PROJECT-25670035, KAKENHI-PROJECT-25670619, KAKENHI-PROJECT-26250041, KAKENHI-PROJECT-26430121, KAKENHI-PROJECT-26670397, KAKENHI-PROJECT-26710013, KAKENHI-PROJECT-26860627
[Journal Article] Hypoxia and fibrosis in chronic kidney disease: crossing at pericytes.2014
- Author(s)
  Kawakami T, Mimura I, Shoji K, Tanaka T, Nangaku M
- Journal Title
  
  Kidney International Suppl
  
  Volume: 4 Pages: 107-112
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26860627
[Presentation] HIF-PH阻害剤の課題と展望2023
- Author(s)
  三村　維真理
- Organizer
  日本透析学会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08604
[Presentation] 腎線維化に寄与するエピジェネティックメモリーの分子機序解明2023
- Author(s)
  三村　維真理
- Organizer
  日本腎臓学会西部学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08604
[Presentation] INO80, a chromatin remodeling factor, inhibits PMAIP1 by exchanging H2A.Z.and H2A in renal tubular cells.2023
- Author(s)
  三村　維真理
- Organizer
  日本分子生物学会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08604
[Presentation] HIF-PHI 概論2023
- Author(s)
  三村　維真理
- Organizer
  日本透析学会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08604
[Presentation] 長鎖非コードRNA、MIR210HGはAKIにおいてmiR-93-5pに競合的に結合しHIF1αを安定化させる2023
- Author(s)
  三村　維真理
- Organizer
  日本腎臓学会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08604
[Presentation] 微小変化型ネフローゼ症候群の初回寛解導入時にヘパリン起因性血小板減少症(HIT)を合併した一例2022
- Author(s)
  北山　智草, 友田　寛人, 松浦　亮, 三村　維真理, 南學　正臣.
- Organizer
  日本腎臓学会東部学術集会
- Data Source
  KAKENHI-PROJECT-20K08604
[Presentation] AKI-to-CKDへの進展を抑制するヒストン修飾阻害薬の役割2022
- Author(s)
  三村　維真理
- Organizer
  第65回日本腎臓学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08604
[Presentation] DKDに寄与するエピジェネティックメモリー2022
- Author(s)
  三村　維真理
- Organizer
  日本腎臓学会西部学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08604
[Presentation] H3K27脱メチル化酵素阻害薬GSKJ4の腎繊維化に与える影響2021
- Author(s)
  佐藤大、三村維真理、田中哲洋、南学正臣
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K08604
[Presentation] H3K27脱メチル化酵素阻害薬であるGSKJ4の腎繊維化に与える影響2021
- Author(s)
  佐藤大、三村維真理、山崎智貴、伊藤理加、南学正臣
- Organizer
  第62回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-20K08604
[Presentation] 腎とエピゲノム創薬と核酸医薬の将来2020
- Author(s)
  三村　維真理
- Organizer
  日本腎臓学会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08604
[Presentation] クロマチンリモデリング因子INO80は腎尿細管細胞のアポトーシスを抑制する2019
- Author(s)
  三村維真理, 三浦理加，佐藤大, 田中哲洋, 南学正臣
- Organizer
  第42回日本分子生物学会総会
- Data Source
  KAKENHI-PROJECT-16K19477
[Presentation] Dznep, a histone modifier, reduces tubulointerstitial fibrosis via decrease of TIMP2.2019
- Author(s)
  Imari Mimura, Yosuke Hirakawa, Yasuharu Kanki, Tetsuhiro Tanaka, Hiroyuki Aburatani, Masaomi Nangaku
- Organizer
  ヨーロッパ腎臓学会（ERA-EDTA）2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19477
[Presentation] クロマチンリモデリング因子INO80は腎尿細管細胞のアポトーシスを抑制する2019
- Author(s)
  三浦　理加, 三村　維真理, 佐藤　大,　田中　哲洋, 南学　正臣
- Organizer
  第62回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-16K19477
[Presentation] 低酸素下で腎尿細管細胞のアポトーシスを抑制するクロマチンリモデリング因子INO80の分子メカニズムの解明2019
- Author(s)
  三村　維真理, 三浦　理加,佐藤　大,　田中　哲洋, 南学　正臣
- Organizer
  低酸素研究会
- Data Source
  KAKENHI-PROJECT-16K19477
[Presentation] INO80 inhibits tubulointerstitial apoptosis under hypoxia.2019
- Author(s)
  Rika Miura, Imari Mimura, Dai Sato, Tetsuhiro Tanaka, Masaomi Nangaku
- Organizer
  アメリカ腎臓学会（American Society of Nephrology)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19477
[Presentation] 低酸素下におけるエピジェネティックな遺伝子発現制御とその機能解明2018
- Author(s)
  三村　維真理
- Organizer
  日本生化学大会
- Invited
- Data Source
  KAKENHI-PROJECT-16K19477
[Presentation] Dznep reduces tubulointerstitial fibrosis via decrease of TIMP2.2018
- Author(s)
  Mimura I, Hirakawa Y, Kanki Y, Suzuki Y, Aburatani H, Tetsuhiro Tanaka, Nangaku M.
- Organizer
  International Society of Nephrology Frontiers 2018.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19477
[Presentation] Identification of novel epigenetic factors in chronic kidney diseases.2018
- Author(s)
  三村　維真理
- Organizer
  Hypoxia Research Meeting 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19477
[Presentation] ヒストン修飾阻害薬Dznepによる腎尿細管間質線維化抑制のメカニズムの解明2018
- Author(s)
  三村　維真理、平川　陽亮、神吉　康晴、田中　哲洋、鈴木　穣、油谷　浩幸、南学　正臣
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-16K19477
[Presentation] 腎臓領域におけるエピジェネティクスの進展2016
- Author(s)
  三村　維真理
- Organizer
  第17回神田川腎セミナー
- Place of Presentation
  経団連会館（東京都千代田区）
- Year and Date
  2016-01-29
- Invited
- Data Source
  KAKENHI-PROJECT-26860627
[Presentation] りん光寿命測定を用いた腎臓尿細管細胞内分圧の測定2015
- Author(s)
  平川陽亮、吉原利忠、神谷真子、三村維真理、田中真司、田中哲洋、浦野泰照、飛田成史、南学正臣
- Organizer
  第３８回日本分子生物学会年会・第８８回日本生化学会大会合同大会
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2015-12-04
- Data Source
  KAKENHI-PROJECT-15H04835
[Presentation] Detection and quantification of intracellular hypoxia of kidney by phosphorescence lifetime measurement using BTPDM1.2015
- Author(s)
  平川陽亮、三村維真理、吉原利忠、神谷真子、浦野泰照、飛田成史、南学正臣
- Organizer
  第3回低酸素研究会
- Place of Presentation
  早稲田大学先端生命医科学センター（東京都新宿区）
- Year and Date
  2015-07-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860627
[Presentation] りん光寿命測定を用いた生体内での尿細管細胞内低酸素の検出2015
- Author(s)
  平川陽亮、三村維真理、吉原利忠、神谷真子、浦野泰照、飛田成史、南学正臣
- Organizer
  第6回分子腎臓フォーラム
- Place of Presentation
  グランフロント大阪（大阪府大阪市）
- Year and Date
  2015-09-05
- Data Source
  KAKENHI-PROJECT-26860627
[Presentation] Quantitating intracellular oxygen tension in kidney by phosphorescence lifetime measurement.2015
- Author(s)
  Yosuke, Hirakawa, Imari, Mimura, Toshitada, Yoshihara, Mako, Kamiya, Yasuteru, Urano, Seiji, Tobita, Masaomi, Nangaku
- Organizer
  American Society of Nephrology
- Place of Presentation
  SanDiego（アメリカ合衆国）
- Year and Date
  2015-11-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860627
[Presentation] りん光寿命測定を用いた腎の低酸素の検出と定量化2015
- Author(s)
  平川陽亮、三村維真理、吉原利忠、神谷真子、浦野泰照、飛田成史、南学正臣
- Organizer
  第58回日本腎臓学会
- Place of Presentation
  名古屋国際会議場(愛知県名古屋市）
- Year and Date
  2015-06-05
- Data Source
  KAKENHI-PROJECT-26860627
[Presentation] Quantitating Intracellular Oxygen Tension in Kidney by Phosphorescence Lifetime Measurement.2015
- Author(s)
  Yosuke Hirakawa, Imari Mimura, Toshitada Yoshihara, Mako Kamiya, Yasuteru Urano, Seiji Tobita, Masaomi Nangaku.
- Organizer
  The 49th Annual Meeting of the American Society of Nephrology
- Place of Presentation
  San Diego, USA
- Year and Date
  2015-11-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04835
[Presentation] Estimation of intracellular oxygen concentration in diabetic kidney by phosphorescence lifetime measurement.2015
- Author(s)
  Hirakawa Y, Mimura I, Yoshihara T, Kamiya M, Tanaka S, Tanaka T, Inagi R, Urano Y, Tobita S, Nangaku M.
- Organizer
  Keystone Symposia: Diabetes: New insights into molecular mechanisms and therapeutic strategies.
- Place of Presentation
  ウエスティン都ホテル京都（京都府京都市）
- Year and Date
  2015-10-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04835
[Presentation] 低酸素とTGF-βは、下流にあるIGFBP3を介して、尿細管上皮細胞にapoptosisを誘導する2015
- Author(s)
  串田夏樹、野村征太郎、藤田隆教、三村維真理、南学正臣、油谷浩幸
- Organizer
  第38回日本分子生物学会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26860627
[Presentation] Identification of novel microRNAs inhibiting tubulointerstitial fibrosis.2015
- Author(s)
  三村　維真理
- Organizer
  Kidney Summit
- Place of Presentation
  第一ホテル東京（東京都港区）
- Year and Date
  2015-12-20
- Data Source
  KAKENHI-PROJECT-26860627
[Presentation] Estimation of intracellular oxygen concentration in diabetic kidney by phosphorescence lifetime measurement2015
- Author(s)
  Yosuke, Hirakawa, Imari, Mimura, Toshitada, Yoshihara, Mako, Kamiya, Yasuteru, Urano, Seiji, Tobita, Masaomi, Nangaku
- Organizer
  Keystone Symposia 2015
- Place of Presentation
  ウェスティン都ホテル京都（京都府京都市）
- Year and Date
  2015-10-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860627
[Presentation] 低酸素とTGF-βは、下流にある IGFBP3 を介して、尿細管上皮細胞に apoptosis を誘導する．2015
- Author(s)
  串田夏樹、野村征太郎、藤田隆教、三村維真理、南学正臣、油谷浩幸．
- Organizer
  第３８回日本分子生物学会年会・第８８回日本生化学会大会合同大会
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15H04835
[Presentation] りん光寿命測定を用いた腎臓尿細管細胞内酸素分圧の測定2015
- Author(s)
  平川陽亮、三村維真理、吉原利忠、神谷真子、浦野泰照、飛田成史、南学正臣
- Organizer
  第38回日本分子生物学会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-04
- Data Source
  KAKENHI-PROJECT-26860627
[Presentation] 慢性腎臓病の進展とエピゲノム~低酸素刺激によるクロマチン立体構造変化2014
- Author(s)
  三村　維真理
- Organizer
  第37回日本分子生物学会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-11-25
- Invited
- Data Source
  KAKENHI-PROJECT-26860627
[Presentation] エピジェネティクスからみた慢性腎臓病―病態の解明と新規治療法に向けて2014
- Author(s)
  三村　維真理
- Organizer
  第57回日本腎臓学会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-07-05
- Invited
- Data Source
  KAKENHI-PROJECT-26860627

1. Nangaku Masaomi (90311620)

# of Collaborated Projects: 4 results

# of Collaborated Products: 18 results
2. 稲城玲子 (50232509)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
3. 田中哲洋 (90508079)

# of Collaborated Projects: 3 results

# of Collaborated Products: 10 results
4. 西裕志 (90784174)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 川上貴久 (10722093)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 加藤秀樹 (90625237)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 正路久美 (00439423)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 和田健彦 (90447409)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 平川陽亮 (10780736)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 倉田遊

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

Mimura Imari 三村 維真理

MIMURA IMARI 三村 維真理

Research Projects

Research Products

Co-Researchers

急性腎障害から低酸素メモリーを介した慢性腎臓病発症機序の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

HIFの活性化の腎臓における細胞特異的影響の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ヒストン修飾阻害薬GSKJ4による腎尿細管間質線維化の病態解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of metabolic reprogramming in the kidney and development of novel therapeutic approaches utilizing HIF against kidney disease

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional analysis of novel microRNA inhibiting tubulointerstitial fibrosis.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Metabolic Reprogramming and Hypoxic Memory in Kidney Disease

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of novel transcriptional mechanisms and identification of non-coding RNAs contributing renal fibrosis.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Biomarkers in Diseases.: Methods, Discoveries and Applications. Biomarkers in Kidney Disease.2015

Author(s)

Total Pages

Publisher

Data Source

[Book] 日本腎臓学会雑誌2015

Author(s)

Total Pages

Publisher

Data Source

[Book] 医学のあゆみ2014

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Epigenetic roles in clonal hematopoiesis and aging kidney-related chronic kidney disease2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Chromatin remodeling factor, INO80, inhibits PMAIP1 in renal tubular cells via exchange of histone variant H2A.Z. for H2A2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Epigenetic regulation of angiogenesis and ischemic response by long noncoding RNA LEENE in diabetes2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ABCA1 deficiency contributes to podocyte pyroptosis priming via the APE1/IRF1 axis in diabetic kidney disease2023

Author(s)

Journal Title

Mimura Imari 三村維真理

MIMURA IMARI 三村維真理