Pyko Ilya Pyko Ilya

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PYKO Ilya ピコイリア

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Researcher Number	00731853
Affiliation (based on the past Project Information) *help	2016 – 2019: 金沢大学, がん進展制御研究所, 博士研究員 2015: 金沢大学, がん進展制御研究所, 研究員 2014: 金沢大学, がん進展制御研究所, 博士研究員
Review Section/Research Field	Principal Investigator Neurosurgery / Basic Section 56010:Neurosurgery-related
Keywords	Principal Investigator temozolomide / glioblastoma / GSK3β / GSK 3β / mesenchymal stem cells / cancer stem-like cells / GBM stem-like cells

Investigation of putative roles for GSK3b in glioblastoma stemness phenotype and the underlying biological mechanismsPrincipal Investigator
- Principal Investigator
  
  Pyko Ilya
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Kanazawa University
Investigation of the therapeutic interaction of mesenchymal stem cells with glioblastoma stem-like cells and its biological mechanismPrincipal Investigator
- Principal Investigator
  
  Pyko Ilya
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurosurgery
- Research Institution
  Kanazawa University
Development of combined cellular and molecular target-directed therapies for glioblastomaPrincipal Investigator
- Principal Investigator
  
  Pyko Ilya
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Neurosurgery
- Research Institution
  Kanazawa University

All 2019 2018 2017 2016 2015 Other

All Journal Article Presentation

[Journal Article] Clinical features of pituitary adenomas with apoplexy in emergency situations2019
- Author(s)
  Pyko Ilya, Hayashi Ya, Sasagawa Y, Kita D, Fukui I, Oishi M, Nakada M.
- Journal Title
  
  Neurosurgery Emergency
  
  Volume: 24 Pages: 28-31
- NAID
  130007623407
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K16553
[Journal Article] Implication of GPR40 Signaling in the Subventricular Zone Neurogenesis after Ischemia via Cross-Talk between Neural Progenitors and Microglia.2018
- Author(s)
  Dazortsava MY, Pyko IV, Boneva NB, Tonchev AB, Zhu H, Sawamoto K, Minabe Y, Yamashima T.
- Journal Title
  
  J Alzheimers Dis Parkinsonism
  
  Volume: 8 Issue: 06 Pages: 454-454
- DOI
  10.4172/2161-0460.1000454
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16553, KAKENHI-PROJECT-16K01814
[Journal Article] Glycogen synthase kinase 3β is a pivotal mediator in cancer invasion and resistance to therapy.2016
- Author(s)
  Domoto T, et al, Minamoto T.
- Journal Title
  
  Cancer Sci
  
  Volume: 107 Issue: 10 Pages: 1363-72
- DOI
  10.1111/cas.13028
- NAID
  120005895690
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04928, KAKENHI-PROJECT-26293322, KAKENHI-PROJECT-15K15493, KAKENHI-PROJECT-16K19996
[Journal Article] Glycogen synthase kinase 3β sustains invasion of glioblastoma via the focal adhesion kinase, Rac1 and c-Jun N-terminal kinase-mediated pathway.2015
- Author(s)
  Chikano Y, Domoto T, Furuta T, Sabit H, Kitano-Tamura A, Ilya V. Pyko, Takino T, Sai Y, Hayashi Y, Sato H, Miyamoto K, Nakada M, MinamotoT.
- Journal Title
  
  Molecular Cancer Therapeutics
  
  Volume: 14 Issue: 2 Pages: 564-574
- DOI
  10.1158/1535-7163.mct-14-0479
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460382, KAKENHI-PROJECT-25670572, KAKENHI-PROJECT-25860233, KAKENHI-PROJECT-26293322, KAKENHI-PROJECT-26670638, KAKENHI-PROJECT-26893096, KAKENHI-PROJECT-15K15493, KAKENHI-PROJECT-15H04928
[Presentation] Therapeutic interaction of mesenchymal stem cells with glioblastoma cells by glycogen synthase kinase (GSK)3β inhibition2019
- Author(s)
  Ilya Pyko, Takahiro Domoto, Mitsutoshi Nakada, Toshinari Minamoto
- Organizer
  The 78th Annual Meeting of the Japanese Cancer Association
- Data Source
  KAKENHI-PROJECT-18K16553
[Presentation] Pancreatic cancer depends on aberrant glycogen synthase kinase (GSK)-3b for acquiring resistance to gemcitabine (GEM)2019
- Author(s)
  Masahiro Uehara, Takahiro Domoto, Satoshi Takenaka, Diliraba Bolidong, Pyko Ilya V., Takeo Shimasaki, Tomoharu Miyashita,Tetsuo Ohta, Toshinari Minamoto
- Organizer
  The 78th Annual Meeting of the Japanese Cancer Association
- Data Source
  KAKENHI-PROJECT-18K16553
[Presentation] Glycogen synthase kinase 3β induces protooncogenic autophagy in colon cancer.2018
- Author(s)
  Domoto T, Pyko IV, Uehara M, Bolidong D, Minamoto T.
- Organizer
  The 77th Annual Meeting of the Japanese Cancer Association
- Data Source
  KAKENHI-PROJECT-18K16553
[Presentation] Sensitizing patient-derived glioblastoma stem-like cells to temozolomide by glycogen synthase kinase 3β inhibition.2017
- Author(s)
  Pyko IV, Domoto T, Nakada M, Minamoto T.
- Organizer
  The 76th Annual Meeting of the Japan Cancer Association
- Data Source
  KAKENHI-PROJECT-16K19996
[Presentation] Putative role of glycogen synthase kinase (GSK)-3β in acquired resistance to gemcitabine (GEM) in pancreatic cancer.2017
- Author(s)
  Uehara M, Domoto T, Takenaka S, Pyko IV, Shimasaki T, Miyashita T, Ohta T, Minamoto T.
- Organizer
  The 76th Annual Meeting of the Japan Cancer Association
- Data Source
  KAKENHI-PROJECT-16K19996
[Presentation] Aberrant glycogen synthase kinase (GSK)3β participates in proliferation of esophageal squamous cell carcinoma (ESCC).2017
- Author(s)
  Bolidong D, Domoto T, Okumura T, Endo Y, Uehara M, Pyko IV, Miyashita T, Minamoto T.
- Organizer
  The 76th Annual Meeting of the Japan Cancer Association
- Data Source
  KAKENHI-PROJECT-16K19996
[Presentation] Putative role of glycogen synthase kinase (GSK)-3β in acquired resistance to gemcitabine (GEM) in pancreatic cancer.2017
- Author(s)
  Uehara M, Domoto T, Takenaka S, Pyko IV, Shimasaki T, Miyashita T, Ohta T, Minamoto T.
- Organizer
  The 9th International Conference on the International Society of Gastroenterological Carcinogenesis
- Data Source
  KAKENHI-PROJECT-16K19996
[Presentation] Aberrant glycogen synthase kinase (GSK)3β participates in tumor-promoting autophagy in colorectal cancerproliferation of .2017
- Author(s)
  Domoto T, Pyko IV, Uehara M, Bolidong D, Minamoto T.
- Organizer
  The 9th International Conference on the International Society of Gastroenterological Carcinogenesis
- Data Source
  KAKENHI-PROJECT-16K19996
[Presentation] Clinical features of pituitary adenomas with apoplexy on emergency situations2017
- Author(s)
  Pyko Ilya, 林康彦, 笹川泰生, 喜多大輔, 福井一生, 大石正博, 中田光俊
- Organizer
  The 22nd Annual Meeting of the Japan Society of Neurosurgical Emergency
- Place of Presentation
  香川県高松市サンポート2-1高松シンボルタワー
- Year and Date
  2017-02-03
- Data Source
  KAKENHI-PROJECT-16K19996
[Presentation] Sensitizing patient-derived glioblastoma stem-like cells to temozolomide by glycogen synthase kinase 3β inhibition2016
- Author(s)
  Ilya V. Pyko, Takahiro Domoto, Mitsutoshi Nakada, Toshinari Minamoto
- Organizer
  The 75th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  PACIFICO Yokohama
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K19996
[Presentation] Glycogen synthase kinase (GSK)-3β participates in colon cancer cell survival via sustaining tumor-promoting autophagy2016
- Author(s)
  Takahiro Domoto, Masahiro Uehara, Ilya V Pyko, Toshinari Minamoto
- Organizer
  The 75th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  PACIFICO Yokohama
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K19996
[Presentation] Putative role of glycogen synthase kinase (GSK)-3 β in acquired resistance to chemotherapy in pancreatic cancer2016
- Author(s)
  Masahiro Uehara, Takahiro Domoto, Satoshi Takenaka, Osamu Takeuchi, Ilya V Pyko, Takeo Shimasaki, Tomoharu Miyashita, Tetsuo Ohta, Toshinari Minamoto
- Organizer
  The 75th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  PACIFICO Yokohama
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K19996
[Presentation] 大腸がん糖代謝特性におけるGSK3βの役割2015
- Author(s)
  堂本貴寛, 紙健次郎, 廣瀬まゆみ, Ilya V. Pyko, 土原一哉, 曽我朋義, 江角浩安, 源利成
- Organizer
  第3回がんと代謝研究会
- Place of Presentation
  金沢市・県立音楽堂
- Year and Date
  2015-07-16
- Data Source
  KAKENHI-PROJECT-26893096
[Presentation] Glycogen synthase kinase 3β inhibition sensitizes human glioblastoma cells to temozolomide by affecting O6-methylguanine DNA methyltransferase promoter methylation via c-Myc signaling
- Author(s)
  Ilya V. Pyko, Mitsutoshi Nakada, Hemragul Sabit, Lei Teng, Natsuki Furuyama, Yutaka Hayashi, Kazuyuki Kawakami, Toshinari Minamoto, Аliaksandr S. Fedulau and Jun-ichiro Hamada
- Organizer
  Japan Cancer Association (JCA) Symposium
- Place of Presentation
  Kanazawa, Ishikawa, Japan
- Year and Date
  2015-01-21 – 2015-01-22
- Data Source
  KAKENHI-PROJECT-26893096

1. 源利成

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 堂本貴寛

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 佐藤博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Pyko Ilya Pyko Ilya

PYKO Ilya ピコ イリア

Research Projects

Research Products

Co-Researchers

Investigation of putative roles for GSK3b in glioblastoma stemness phenotype and the underlying biological mechanismsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation of the therapeutic interaction of mesenchymal stem cells with glioblastoma stem-like cells and its biological mechanismPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of combined cellular and molecular target-directed therapies for glioblastomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Clinical features of pituitary adenomas with apoplexy in emergency situations2019

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Implication of GPR40 Signaling in the Subventricular Zone Neurogenesis after Ischemia via Cross-Talk between Neural Progenitors and Microglia.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Glycogen synthase kinase 3β is a pivotal mediator in cancer invasion and resistance to therapy.2016

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Glycogen synthase kinase 3β sustains invasion of glioblastoma via the focal adhesion kinase, Rac1 and c-Jun N-terminal kinase-mediated pathway.2015

Author(s)

Journal Title

DOI

Data Source

[Presentation] Therapeutic interaction of mesenchymal stem cells with glioblastoma cells by glycogen synthase kinase (GSK)3β inhibition2019

Author(s)

Organizer

Data Source

[Presentation] Pancreatic cancer depends on aberrant glycogen synthase kinase (GSK)-3b for acquiring resistance to gemcitabine (GEM)2019

Author(s)

Organizer

Data Source

[Presentation] Glycogen synthase kinase 3β induces protooncogenic autophagy in colon cancer.2018

Author(s)

Organizer

Data Source

[Presentation] Sensitizing patient-derived glioblastoma stem-like cells to temozolomide by glycogen synthase kinase 3β inhibition.2017

Author(s)

Organizer

Data Source

[Presentation] Putative role of glycogen synthase kinase (GSK)-3β in acquired resistance to gemcitabine (GEM) in pancreatic cancer.2017

Author(s)

Organizer

Data Source

[Presentation] Aberrant glycogen synthase kinase (GSK)3β participates in proliferation of esophageal squamous cell carcinoma (ESCC).2017

Author(s)

Organizer

Data Source

[Presentation] Putative role of glycogen synthase kinase (GSK)-3β in acquired resistance to gemcitabine (GEM) in pancreatic cancer.2017

Author(s)

Organizer

Data Source

[Presentation] Aberrant glycogen synthase kinase (GSK)3β participates in tumor-promoting autophagy in colorectal cancerproliferation of .2017

Author(s)

Organizer

Data Source

[Presentation] Clinical features of pituitary adenomas with apoplexy on emergency situations2017

Author(s)

Organizer

Place of Presentation

PYKO Ilya ピコイリア