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YONEDA RYOMA  米田 竜馬

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YONEDA Ryoma  米田 竜馬

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Researcher Number 00734881
Other IDs
Affiliation (Current) 2025: 埼玉医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help 2021 – 2024: 埼玉医科大学, 医学部, 講師
2017 – 2020: 埼玉医科大学, 医学部, 助教
Review Section/Research Field
Principal Investigator
Basic Section 48040:Medical biochemistry-related / Transformative Research Areas, Section (II) / Basic Section 50020:Tumor diagnostics and therapeutics-related / Cell biology
Except Principal Investigator
Transformative Research Areas, Section (II)
Keywords
Principal Investigator
m6A修飾 / lncRNA / LLPS / cyclin D1 / m6A / TLS/FUS / RNA methylation / FUS/TLS / 高次クロマチン構造 / 脂質ラフト … More / 液-液相分離 / メゾスケール構造体 / SX-STED / 相分離 / FUS / 核酸医薬 / ALS / TLS / pncRNA / CCND1 / pncRNA-D / RNAメチル化 … More
Except Principal Investigator
領域間連携 / 若手育成 / 軟X線 / STED Less
  • Research Projects

    (5 results)
  • Research Products

    (18 results)
  • Co-Researchers

    (5 People)
  •  生物と無生物をつなぐSTED技術開発の包括的な研究総括

    • Principal Investigator
      黒澤 俊介
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Transformative Research Areas (B)
    • Review Section
      Transformative Research Areas, Section (II)
    • Research Institution
      Tohoku University
  •  分子化合物から細胞内構造体に至るメゾリンク-メゾスケール構造体の形成機構解析-Principal Investigator

    • Principal Investigator
      米田 竜馬
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Transformative Research Areas (B)
    • Review Section
      Transformative Research Areas, Section (II)
    • Research Institution
      Saitama Medical University
  •  ALS病因タンパク質FUSのm6A修飾認識タンパク質としての機能解析Principal Investigator

    • Principal Investigator
      米田 竜馬
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 48040:Medical biochemistry-related
    • Research Institution
      Saitama Medical University
  •  Development of seed sequences for oligonucleotide therapeutics targeting neurodegenerative disordersPrincipal Investigator

    • Principal Investigator
      YONEDA Ryoma
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Saitama Medical University
  •  Regulation of cyclin D1 gene expression by lncRNA transcribed from its promoter regionPrincipal Investigator

    • Principal Investigator
      YONEDA Ryoma
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Cell biology
    • Research Institution
      Saitama Medical University

All 2024 2023 2022 2021 2020 2019 2018 2017

All Journal Article Presentation

  • [Journal Article] Identification of Essential Components of RNA Binding Domain of TLS/FUS2024

    • Author(s)
      Ueda Naomi、Yoneda Ryoma、Kurokawa Riki
    • Journal Title

      Biomedical Sciences

      Volume: 10 Issue: 2 Pages: 30-43

    • DOI

      10.11648/j.bs.20241002.13

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K06392, KAKENHI-PROJECT-20K16452
  • [Journal Article] Identification of Long Noncoding RNA Recognized by RNA-Binding Protein TLS/FUS: Purification of RNAs by Affinity Chromatography of GST-TLS2022

    • Author(s)
      Naomi Ueda, Ryoma Yoneda, Riki Kurokawa
    • Journal Title

      Biomedical Sciences

      Volume: 8(4) Pages: 144-156

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K16452
  • [Journal Article] Non-coding RNA suppresses FUS aggregation caused by mechanistic shear stress on pipetting in a sequence-dependent manner2021

    • Author(s)
      Hamad Nesreen、Yoneda Ryoma、So Masatomo、Kurokawa Riki、Nagata Takashi、Katahira Masato
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1 Pages: 9523-9523

    • DOI

      10.1038/s41598-021-89075-w

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K18065, KAKENHI-PROJECT-20H03192, KAKENHI-PROJECT-18K06939, KAKENHI-PROJECT-20K06524, KAKENHI-PROJECT-20K16452
  • [Journal Article] m 6 A Modified Short RNA Fragments Inhibit Cytoplasmic TLS/FUS Aggregation Induced by Hyperosmotic Stress2021

    • Author(s)
      Ryoma Yoneda, Naomi Ueda, Riki Kurokawa
    • Journal Title

      International Journal of Molecular Sciences

      Volume: Vol.22 Issue: 20 Pages: 11014-11014

    • DOI

      10.3390/ijms222011014

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06939, KAKENHI-PROJECT-20K16452
  • [Journal Article] RNA sequence and length contribute to RNA-induced conformational change of TLS/FUS2020

    • Author(s)
      Hamad Nesreen、Mashima Tsukasa、Yamaoki Yudai、Kondo Keiko、Yoneda Ryoma、Oyoshi Takanori、Kurokawa Riki、Nagata Takashi、Katahira Masato
    • Journal Title

      Scientific Reports

      Volume: 10 Issue: 1 Pages: 2629-2629

    • DOI

      10.1038/s41598-020-59496-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K18065, KAKENHI-PUBLICLY-18H04550, KAKENHI-PROJECT-16K07269, KAKENHI-PROJECT-17K05930, KAKENHI-PROJECT-18K14636, KAKENHI-PROJECT-19K16054, KAKENHI-PUBLICLY-17H05878, KAKENHI-PROJECT-17K14515, KAKENHI-PROJECT-17K07307, KAKENHI-PROJECT-18K19397
  • [Journal Article] Potential Inhibitor Against Phase Separation, 1, 6-hexanediol Specifically Binds to Beta Actin in Nuclear Extract of Human Cell Line2020

    • Author(s)
      Naomi Ueda, Yuki Hirose, Ryoma Yoneda, Toshikazu Bando, Riki Kurokawa
    • Journal Title

      Biomedical Sciences

      Volume: 6 Pages: 88-97

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K16452
  • [Journal Article] Long noncoding RNA pncRNA-D?reduces cyclin D1 gene expression and arrests cell cycle through RNA m6A modification2020

    • Author(s)
      Yoneda Ryoma、Ueda Naomi、Uranishi Kousuke、Hirasaki Masataka、Kurokawa Riki
    • Journal Title

      Journal of Biological Chemistry

      Volume: 295 Issue: 17 Pages: 5626-5639

    • DOI

      10.1074/jbc.ra119.011556

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06939, KAKENHI-PROJECT-17K15604, KAKENHI-PROJECT-17K18065
  • [Journal Article] Arginine methylation of translocated in liposarcoma (TLS) inhibits its binding to long noncoding RNA, abrogating TLS-mediated repression of CBP/p300 activity2018

    • Author(s)
      Cui Wei、Yoneda Ryoma、Ueda Naomi、Kurokawa Riki
    • Journal Title

      Journal of Biological Chemistry

      Volume: 293 Issue: 28 Pages: 10937-10948

    • DOI

      10.1074/jbc.ra117.000598

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K06939, KAKENHI-PROJECT-17K18065
  • [Presentation] m6A修飾認識タンパク質としてのTLS/FUS2023

    • Author(s)
      米田竜馬、上田奈緒美、黒川理樹
    • Organizer
      第46回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-23K06392
  • [Presentation] m6A修飾認識タンパク質としてのTLS/FUS2023

    • Author(s)
      米田竜馬、上田奈緒美、黒川理樹
    • Organizer
      第46回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-20K16452
  • [Presentation] TLS/FUSのm6A修飾readerとしての可能性2022

    • Author(s)
      米田竜馬、上田奈緒美、黒川理樹
    • Organizer
      第45回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-20K16452
  • [Presentation] The effect of m6A RNA on LLPS of TLS/FUS2021

    • Author(s)
      米田竜馬、上田奈緒美、黒川理樹
    • Organizer
      第44回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-20K16452
  • [Presentation] CCND1遺伝子発現におけるlncRNAのm6A修飾の役割2021

    • Author(s)
      米田竜馬、上田奈緒美、浦西洸介、平崎正孝、黒川理樹
    • Organizer
      第43回日本分子生物学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K18065
  • [Presentation] CCND1遺伝子発現におけるlncRNAのm6A修飾の役割2021

    • Author(s)
      米田竜馬、上田奈緒美、浦西洸介、平崎正孝、黒川理樹
    • Organizer
      第43回日本分子生物学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K16452
  • [Presentation] RNA結合タンパク質TLS/FUSの液-液相分離、繊維化に薬剤が与える効果2019

    • Author(s)
      米田 竜馬、上田 奈緒美、金木 清美、板東 俊和、黒川 理樹
    • Organizer
      第42回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-17K18065
  • [Presentation] CCND1プロモーター領域より転写されるlncRNAによる細胞周期への影響2018

    • Author(s)
      米田竜馬、上田奈緒美、黒川理樹
    • Organizer
      日本分子生物学会
    • Data Source
      KAKENHI-PROJECT-17K18065
  • [Presentation] TLS and long noncoding RNA transcribed from the promoter of cyclin D1 repress its mRNA expression2017

    • Author(s)
      Ryoma YONEDA, Wei Cui, Naomi Ueda, Riki Kurokawa
    • Organizer
      第43回内藤コンファレンス
    • Data Source
      KAKENHI-PROJECT-17K18065
  • [Presentation] The effect of m6A modification on lncRNA transcribed from Cyclin D1 promoter2017

    • Author(s)
      Ryoma YONEDA, Wei CUI, Naomi UEDA, and Riki KUROKAWA
    • Organizer
      2017年度生命科学系学会合同年次大会(ConBio2017)
    • Data Source
      KAKENHI-PROJECT-17K18065
  • 1.  黒澤 俊介 (80613637)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  田上 周路 (80420503)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  山本 晃司 (50767150)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  若山 俊隆 (90438862)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  黒川 理樹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results

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