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Morimoto Kenji  森本 健司

ORCIDConnect your ORCID iD *help
Researcher Number 00768806
Other IDs
Affiliation (based on the past Project Information) *help 2022 – 2023: 京都府立医科大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field
Principal Investigator
0901:Oncology and related fields
Keywords
Principal Investigator
KRASG12C変異 / 非小細胞肺癌 / KRAS-G12C変異 / YAP / AXL / KRAS-G12C / 肺癌 / 治療抵抗性
  • Research Projects

    (1 results)
  • Research Products

    (4 results)
  • Co-Researchers

    (3 People)
  •  Investigation of kinase signaling related to early drug tolerance to molecular-targeted drugs and development of therapies to overcome the tolerancePrincipal Investigator

    • Principal Investigator
      Morimoto Kenji
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Review Section
      0901:Oncology and related fields
    • Research Institution
      Kyoto Prefectural University of Medicine

All 2024 2023

All Journal Article Presentation

  • [Journal Article] AXL signal mediates adaptive resistance to KRAS G12C inhibitors in KRAS G12C-mutant tumor cells.2024

    • Author(s)
      Morimoto K, Yamada T, Hirai S, Katayama Y, Fukui S, Sawada R, Tachibana Y, Matsui Y, Nakamura R, Ishida M, Kawachi H, Kunimasa K, Sasaki T, Nishida M, Furuya N, Watanabe S, Shiotsu S, Nishioka N, Horinaka M, Sakai T, Uehara H, Yano S, Son BK, Tokuda S, Takayama K.
    • Journal Title

      Cancer Lett

      Volume: 587 Pages: 216692-216692

    • DOI

      10.1016/j.canlet.2024.216692

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K07607, KAKENHI-PROJECT-21K15513, KAKENHI-PROJECT-22K20833, KAKENHI-PROJECT-23K27609
  • [Presentation] AXL activation promotes adaptive resistance to KRAS-G12C inhibitors in KRAS-G12C-mutated non-small cell lung cancer2024

    • Author(s)
      Kenji Morimoto; Tadaaki Yamada; Soichi Hirai; Yuki Katayama; Kei Kunimasa; Takaaki Sasaki; Makoto Nishida; Satoshi Watanabe; Shinsuke Shiotsu; Hisanori Uehara; Koichi Takayama
    • Organizer
      AACR2024
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K20833
  • [Presentation] AXLシグナル活性化によるKRAS-G12C阻害薬の初期治療抵抗性機構の解明と治療法開発2023

    • Author(s)
      森本健司, 山田忠明, 平井聡一, 片山勇輝, 國政啓, 佐々木高明, 西田真, 渡部聡, 塩津伸介, 西岡直哉, 矢野聖二, 上原久典, 徳田深作, 髙山浩一
    • Organizer
      第64回日本肺癌学会学術集会
    • Data Source
      KAKENHI-PROJECT-22K20833
  • [Presentation] Adaptive resistance to KRAS-G12C inhibitors through AXL activation in KRAS-G12C mutant tumor cells2023

    • Author(s)
      Kenji Morimoto, Tadaaki Yamada, Soichi Hirai, Yuki Kayama, Seiji Yano, Mano Horinaka, Toshiyuki Sakai, Shinsaku Tokuda, Koichi Takayama
    • Organizer
      第82回日本癌学会学術集会
    • Data Source
      KAKENHI-PROJECT-22K20833
  • 1.  YAMADA Tadaaki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 2.  徳田 深作
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 3.  高山 浩一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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