yako hideji 八子英司

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YAKO Hideji 八子英司

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Researcher Number	00768880
Other IDs
Affiliation (Current)	2025: 東京薬科大学, 生命科学部, 助教
Affiliation (based on the past Project Information) *help	2020 – 2021: 公益財団法人東京都医学総合研究所, 疾患制御研究分野, 研究員
Review Section/Research Field	Principal Investigator Basic Section 48020:Physiology-related
Keywords	Principal Investigator ATP / 糖代謝 / クエン酸回路 / PARP / ピルビン酸 / 細胞死 / 高グルコース / 解糖系 / TCAサイクル / 外因性ピルビン酸

Analysis of molecular mechanism of pyruvate-starved induced cell death under high-glucose conditionsPrincipal Investigator
- Principal Investigator
  
  YAKO Hideji
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Tokyo Metropolitan Institute of Medical Science

All 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] Exendin-4 Promotes Schwann Cell Survival/Migration and Myelination In Vitro2021
- Author(s)
  Takaku Shizuka、Tsukamoto Masami、Niimi Naoko、Yako Hideji、Sango Kazunori
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 6 Pages: 2971-2971
- DOI
  10.3390/ijms22062971
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07773, KAKENHI-PROJECT-20K16127, KAKENHI-PROJECT-20K07027
[Journal Article] Aldose Reductase and the Polyol Pathway in Schwann Cells: Old and New Problems2021
- Author(s)
  Niimi Naoko、Yako Hideji、Takaku Shizuka、Chung Sookja K.、Sango Kazunori
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 3 Pages: 1031-1031
- DOI
  10.3390/ijms22031031
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07773, KAKENHI-PROJECT-20K16127, KAKENHI-PROJECT-20K07027
[Journal Article] Role of pyruvate in maintaining cell viability and energy production under high-glucose conditions2021
- Author(s)
  Yako Hideji、Niimi Naoko、Kato Ayako、Takaku Shizuka、Tatsumi Yasuaki、Nishito Yasumasa、Kato Koichi、Sango Kazunori
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 18910-18910
- DOI
  10.1038/s41598-021-98082-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K16127, KAKENHI-PROJECT-20K07027, KAKENHI-PROJECT-20K07773, KAKENHI-PROJECT-21K06718
[Journal Article] Glycolaldehyde induces sensory neuron death through activation of the c-Jun N-terminal kinase and p-38 MAP kinase pathways.2019
- Author(s)
  Akamine T, Takaku S, Suzuki M, Niimi N, Yako H, Matoba K, Kawanami D, Utsunomiya K, Nishimura R, Sango K
- Journal Title
  
  Histochemistry and cell biology
  
  Volume: 153 Issue: 2 Pages: 111-119
- DOI
  10.1007/s00418-019-01830-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07987, KAKENHI-PROJECT-19K08714, KAKENHI-PROJECT-18K15985, KAKENHI-PROJECT-20K07773, KAKENHI-PROJECT-20K16127
[Presentation] Exogenous pyruvate maintains glycolysis-TCA cycle flux through PARP-dependent and independent cascades under high-glucose condition2022
- Author(s)
  Hideji Yako, Kazunori Sango
- Organizer
  第99回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-20K16127
[Presentation] 高グルコース・外因性ピルビン酸欠乏環境下での解糖系変動に対するHIF1αと2-オキソグルタル酸の検証2021
- Author(s)
  八子英司,加藤文子,新見直子,高久静香,加藤宏一,三五一憲
- Organizer
  第64回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-20K16127
[Presentation] 高グルコース・外因性ピルビン酸環境下で誘導されるシュワン細胞死と解糖系-TCA回路フラックス減少におけるPARPの関与2021
- Author(s)
  八子英司,加藤文子,新見直子,高久静香,加藤宏一,三五一憲
- Organizer
  第36回日本糖尿病合併症学会
- Data Source
  KAKENHI-PROJECT-20K16127
[Presentation] 高グルコース・外因性ピルビン酸欠乏環境下における、ベンフォチアミンのシュワン細胞死抑制メカニズムの検証2020
- Author(s)
  八子英司,加藤文子,新見直子,高久静香,加藤宏一,三五一憲
- Organizer
  第63回日本糖尿病学会
- Data Source
  KAKENHI-PROJECT-20K16127
[Presentation] 高グルコース・外因性ピルビン酸欠乏環境下で誘導されるシュワン細胞死には、PARPを介したGAPDH活性低下が関与する2020
- Author(s)
  八子英司,加藤文子,新見直子,高久静香,加藤宏一,三五一憲
- Organizer
  第63回日本糖尿病学会
- Data Source
  KAKENHI-PROJECT-20K16127

1. SUZUKI Mari

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 三五一憲

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

yako hideji 八子 英司

YAKO Hideji 八子 英司

Research Projects

Research Products

Co-Researchers

Analysis of molecular mechanism of pyruvate-starved induced cell death under high-glucose conditionsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Exendin-4 Promotes Schwann Cell Survival/Migration and Myelination In Vitro2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Aldose Reductase and the Polyol Pathway in Schwann Cells: Old and New Problems2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Role of pyruvate in maintaining cell viability and energy production under high-glucose conditions2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Glycolaldehyde induces sensory neuron death through activation of the c-Jun N-terminal kinase and p-38 MAP kinase pathways.2019

Author(s)

Journal Title

DOI

Data Source

[Presentation] Exogenous pyruvate maintains glycolysis-TCA cycle flux through PARP-dependent and independent cascades under high-glucose condition2022

Author(s)

Organizer

Data Source

[Presentation] 高グルコース・外因性ピルビン酸欠乏環境下での解糖系変動に対するHIF1αと2-オキソグルタル酸の検証2021

Author(s)

Organizer

Data Source

[Presentation] 高グルコース・外因性ピルビン酸環境下で誘導されるシュワン細胞死と解糖系-TCA回路フラックス減少におけるPARPの関与2021

Author(s)

Organizer

Data Source

[Presentation] 高グルコース・外因性ピルビン酸欠乏環境下における、ベンフォチアミンのシュワン細胞死抑制メカニズムの検証2020

Author(s)

Organizer

Data Source

[Presentation] 高グルコース・外因性ピルビン酸欠乏環境下で誘導されるシュワン細胞死には、PARPを介したGAPDH活性低下が関与する2020

Author(s)

Organizer

Data Source

yako hideji 八子英司

YAKO Hideji 八子英司