Mizuno Katsutoshi 水野克俊

Researcher Number	00777774
Other IDs
Affiliation (Current)	2025: 福井大学, 学術研究院医学系部門, 助教
Affiliation (based on the past Project Information) *help	2025: 福井大学, 学術研究院医学系部門, 助教 2020 – 2023: 福井大学, 学術研究院医学系部門, 助教 2018 – 2019: 国立研究開発法人理化学研究所, 生命機能科学研究センター, 研究員 2017: 国立研究開発法人理化学研究所, 多細胞システム形成研究センター, 研究員
Review Section/Research Field	Principal Investigator Basic Section 44040:Morphology and anatomical structure-related / Basic Section 44010:Cell biology-related / Morphology/Structure
Keywords	Principal Investigator ダイニン / 左右軸 / 左右 / カルシウム / 繊毛 / 細胞質ダイニン / 神経軸索 / インポーチン / 発生・分化

繊毛・鞭毛において新規に見出されたタンパク質メチル化の機能解析Principal Investigator
- Principal Investigator
  
  水野克俊
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44040:Morphology and anatomical structure-related
- Research Institution
  University of Fukui
神経軸索性インポーチンによる細胞質ダイニン制御機構の解明Principal Investigator
- Principal Investigator
  
  水野克俊
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  University of Fukui
Functional analysis of nodal cilia derived calcium influx in left-right symmetry breakingPrincipal Investigator
- Principal Investigator
  
  Mizuno Katsutoshi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44040:Morphology and anatomical structure-related
- Research Institution
  University of Fukui
  Institute of Physical and Chemical Research
Visualization of ciliary Calcium that initiate Left-Right AsymmetryPrincipal Investigator
- Principal Investigator
  
  Mizuno Katsutoshi
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Morphology/Structure
- Research Institution
  Institute of Physical and Chemical Research

All 2023 2022 2020 2019 2018 2017

All Journal Article Presentation

[Journal Article] Immotile cilia mechanically sense the direction of fluid flow for left-right determination2023
- Author(s)
  Katoh Takanobu A.、Omori Toshihiro、Mizuno Katsutoshi、Sai Xiaorei、Minegishi Katsura、Ikawa Yayoi、Nishimura Hiromi、Itabashi Takeshi、Kajikawa Eriko、Hiver Sylvain、Iwane Atsuko H.、Ishikawa Takuji、Okada Yasushi、Nishizaka Takayuki、Hamada Hiroshi
- Journal Title
  
  Science
  
  Volume: 379 Issue: 6627 Pages: 66-71
- DOI
  10.1126/science.abq8148
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06220, KAKENHI-PROJECT-21K15096, KAKENHI-PLANNED-21H05308, KAKENHI-PROJECT-22H04926, KAKENHI-PROJECT-20H00472, KAKENHI-PROJECT-21H04999, KAKENHI-PROJECT-23K23853
[Journal Article] Immotile cilia of the mouse node sense a fluid flow?induced mechanical force for left-right symmetry breaking2022
- Author(s)
  Katoh Takanobu A.、Omori Toshihiro、Mizuno Katsutoshi、Sai Xiaorei、Minegishi Katsura、Ikawa Yayoi、Nishimura Hiromi、Itabashi Takeshi、Kajikawa Eriko、Hiver Sylvain、Iwane Atsuko H.、Ishikawa Takuji、Okada Yasushi、Nishizaka Takayuki、Hamada Hiroshi
- Journal Title
  
  Biorxiv
  
  Volume: -
- DOI
  10.1101/2022.04.11.487968
- Open Access
- Data Source
  KAKENHI-PROJECT-19K06753
[Journal Article] Planar cell polarity?dependent asymmetric organization of microtubules for polarized positioning of the basal body in node cells2022
- Author(s)
  Sai Xiaorei、Ikawa Yayoi、Nishimura Hiromi、Mizuno Katsutoshi、Kajikawa Eriko、Katoh Takanobu A.、Kimura Toshiya、Shiratori Hidetaka、Takaoka Katsuyoshi、Hamada Hiroshi、Minegishi Katsura
- Journal Title
  
  Development
  
  Volume: - Issue: 9 Pages: 200315-200315
- DOI
  10.1242/dev.200315
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06753, KAKENHI-PROJECT-20K06673, KAKENHI-PROJECT-22K06220, KAKENHI-PROJECT-22K07360, KAKENHI-PROJECT-21K15096, KAKENHI-PROJECT-20H00472
[Journal Article] CFAP45 deficiency causes situs abnormalities and asthenospermia by disrupting an axonemal adenine nucleotide homeostasis module2020
- Author(s)
  Gerard W. Dougherty, Katsutoshi Mizuno, 他25名, Ide T, Twan WK, 他9名, Aviram M, Kaiser T, Memari Y, Dzeja PP, Dworniczak B, Ueffing M, Roepman R, Bartscherer K, Katsanis N, Davis EE, Amirav I, Hamada H, Omran H.
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 5520-5520
- DOI
  10.1038/s41467-020-19113-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06753, KAKENHI-PROJECT-20K06673, KAKENHI-PUBLICLY-20H05369, KAKENHI-PROJECT-19K23756
[Journal Article] Role of Ca2+ transients at the node of the mouse embryo in breaking of left-right symmetry2020
- Author(s)
  Mizuno Katsutoshi、Shiozawa Kei、Katoh Takanobu A.、Minegishi Katsura、Ide Takahiro、Ikawa Yayoi、Nishimura Hiromi、Takaoka Katsuyoshi、Itabashi Takeshi、Iwane Atsuko H.、Nakai Junichi、Shiratori Hidetaka、Hamada Hiroshi
- Journal Title
  
  Science Advances
  
  Volume: 6 Issue: 30
- DOI
  10.1126/sciadv.aba1195
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06753, KAKENHI-PROJECT-20K06673, KAKENHI-PROJECT-19K23761, KAKENHI-PROJECT-20H00472, KAKENHI-PUBLICLY-20H05369, KAKENHI-PROJECT-19K23756
[Journal Article] Nodal paralogues underlie distinct mechanisms for visceral left-right asymmetry in reptiles and mammals2020
- Author(s)
  Kajikawa Eriko、Horo Uzuki、Ide Takahiro、Mizuno Katsutoshi、Minegishi Katsura、Hara Yuichiro、Ikawa Yayoi、Nishimura Hiromi、Uchikawa Masanori、Kiyonari Hiroshi、Kuraku Shigehiro、Hamada Hiroshi
- Journal Title
  
  Nature Ecology & Evolution
  
  Volume: 4 Issue: 2 Pages: 261-269
- DOI
  10.1038/s41559-019-1072-2
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06753, KAKENHI-PROJECT-18K14725, KAKENHI-PROJECT-17H01435, KAKENHI-PROJECT-16K07370, KAKENHI-PROJECT-17K07426
[Journal Article] Ciliogenesis‐coupled accumulation of IFT‐B proteins in a novel cytoplasmic compartment2019
- Author(s)
  Lamri Lynda、Twan Wang Kyaw、Katoh Takanobu A.、Botilde Yanick、Takaoka Katsuyoshi、Ikawa Yayoi、Nishimura Hiromi、Fukumoto Akemi、Minegishi Katsura、Mizuno Katsutoshi、Hamada Hiroshi
- Journal Title
  
  Genes to Cells
  
  Volume: 24 Issue: 11 Pages: 731-745
- DOI
  10.1111/gtc.12722
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06753, KAKENHI-PROJECT-18K14725, KAKENHI-PROJECT-19K23761, KAKENHI-PROJECT-17H01435, KAKENHI-PROJECT-19K23756
[Journal Article] 体の左右非対称性決定におけるノード繊毛とカルシウムの機能2018
- Author(s)
  水野克俊
- Journal Title
  
  実験医学 2018年4月号: 一次繊毛の世界
  
  Volume: 36 Pages: 950-954
- Data Source
  KAKENHI-PROJECT-17K15153
[Journal Article] Crystal structure of a Ca2+-dependent regulator of flagellar motility reveals the open-closed structural transition2018
- Author(s)
  Tomoki Shojima, Feng Hou, Yusuke Takahashi, Yoshitaka Matsumura, Masahiko Okai, Akira Nakamura, Katsutoshi Mizuno, Kazuo Inaba, Masaki Kojima, Takuya Miyakawa & Masaru Tanokura
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 2014-2014
- DOI
  10.1038/s41598-018-19898-7
- NAID
  120007134496
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15153, KAKENHI-PROJECT-15H05621
[Journal Article] Calaxin establishes basal body orientation and coordinates movement of monocilia in sea urchin embryos2017
- Author(s)
  Mizuno Katsutoshi、Shiba Kogiku、Yaguchi Junko、Shibata Daisuke、Yaguchi Shunsuke、Pruliere Gerard、Chenevert Janet、Inaba Kazuo
- Journal Title
  
  Sci Rep.
  
  Volume: 7 Issue: 1 Pages: 10751-10751
- DOI
  10.1038/s41598-017-10822-z
- NAID
  120007134832
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07337, KAKENHI-PROJECT-17K15153, KAKENHI-PROJECT-17H01440
[Journal Article] Protein arginine methyltransferases interact with intraflagellar transport particles and change location during flagellar growth and resorption2017
- Author(s)
  Katsutoshi Mizuno, Roger D. Sloboda
- Journal Title
  
  Molecular Biology of the Cell
  
  Volume: 28(9) Issue: 9 Pages: 1208-1222
- DOI
  10.1091/mbc.e16-11-0774
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15153
[Presentation] A novel neuronal function of mouse KPNA1/importin alpha 5 in axonal transport2023
- Author(s)
  Katsutoshi Mizuno, Masaki Sugahara, Ryota Kato, Hirotaka Nomiya, Takafumi Itoh, Satoshi Fujita, Masami Yamada
- Organizer
  第75回日本細胞生物学会年会
- Data Source
  KAKENHI-PROJECT-22K06220
[Presentation] 神経軸索輸送における核移行因子KPNA1の新規機能2023
- Author(s)
  水野克俊, 菅原将樹, 加藤諒大, 野宮廣貴, 伊藤貴文, 藤田聡, 山田雅己
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K06220
[Presentation] 神経細胞における軸索性インポーチンの新規機能解析2023
- Author(s)
  水野克俊, 菅原将樹, 加藤諒大, 野宮廣貴, 伊藤貴文, 藤田聡, 山田雅己
- Organizer
  第19回福井大学ライフサイエンスイノベーションセンター研究交流会
- Invited
- Data Source
  KAKENHI-PROJECT-22K06220
[Presentation] 膠芽腫細胞の遊走に対するImportin α1の役割に関する研究2022
- Author(s)
  山内貴寛、野宮廣貴、水野克俊、菊田健一郎、山田雅己
- Organizer
  第22回日本分子脳神経外科学会
- Data Source
  KAKENHI-PROJECT-22K06220
[Presentation] 軸索輸送におけるKPNA1複合体関連因子の同定と機能解析2022
- Author(s)
  菅原将樹、水野克俊、加藤諒大、野宮廣貴、宮本洋一、岡正啓、疋田貴俊、伊藤貴文、藤田聡、山田雅己
- Organizer
  第74回日本細胞生物学会大会
- Data Source
  KAKENHI-PROJECT-22K06220
[Presentation] 神経細胞遊走活性を指標としたKPNA1/Importin α1の新規機能の解明2022
- Author(s)
  加藤諒大、水野克俊、菅原将樹、野宮廣貴、宮本洋一、岡正啓、疋田貴俊、伊藤貴文、藤田聡、山田雅己
- Organizer
  第74回日本細胞生物学会大会
- Data Source
  KAKENHI-PROJECT-22K06220
[Presentation] マウスノード不動繊毛は変形の向きを感知して左右軸を決定する: 非対称性を生み出すメカニカルな機構2022
- Author(s)
  加藤孝信、大森俊宏、水野克俊、石川拓司、濱田博司
- Organizer
  第74回日本細胞生物学会大会
- Data Source
  KAKENHI-PROJECT-22K06220
[Presentation] 左右軸決定における、マウスノード不動繊毛への機械刺激依存的なCerl2 mRNA分解の活性化2022
- Author(s)
  加藤孝信 , 大森俊宏 , 水野克俊, 石川拓司, 濱田博司
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-19K06753
[Presentation] KPNAN1/インポーチンα1のマウス神経軸索輸送・神経遊走における新規機能2022
- Author(s)
  水野克俊、菅原将樹、加藤諒大、野宮廣貴、宮本洋一、岡正啓、疋田貴俊、伊藤貴文、藤田聡、山田雅己
- Organizer
  第74回日本細胞生物学会大会
- Data Source
  KAKENHI-PROJECT-22K06220
[Presentation] 左右軸決定における、マウスノード不動繊毛への機械刺激依存的な Cerl2 mRNA 分解の活性化2022
- Author(s)
  加藤孝信 , 大森俊宏 , 水野克俊, 石川拓司, 濱田博司
- Organizer
  日本生物物理学会
- Data Source
  KAKENHI-PROJECT-19K06753
[Presentation] Importin alpha 1/KPNA1は神経細胞遊走を制御する2022
- Author(s)
  加藤諒大、水野克俊、菅原将樹、野宮廣貴、藤田聡、山田雅己
- Organizer
  日本生化学会北陸支部会第40回大会
- Data Source
  KAKENHI-PROJECT-22K06220
[Presentation] マウスノード不動繊毛は変形の向きを感知して左右軸を決定する: 非対称性を生み出すメカニカルな機構2022
- Author(s)
  加藤孝信、大森俊宏、水野克俊、石橋岳志、岩根敦子、石川拓司、岡田康志、西坂崇之、濱田博司
- Organizer
  第60回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-22K06220
[Presentation] 繊毛への機械刺激依存的な、マウスノードクラウン細胞におけるmRNA分解2020
- Author(s)
  Takanobu A Katoh, Katsutoshi Mizuno, Hiroshi Hamada1
- Organizer
  日本生物物理学会第58回年会
- Data Source
  KAKENHI-PROJECT-19K06753
[Presentation] Functional analysis of intraciliary Calcium signal in mouse Left-Right symmetry breaking.2019
- Author(s)
  Katsutoshi Mizuno, Takanobu A. Kato, Kei Shiozawa, Hiroshi Hamada.
- Organizer
  Cold Spring Harbor Asia Cilia & Centrosome.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06753
[Presentation] Functional analysis of intraciliary Calcium signal in mouse Left-Right symmetry breaking,2019
- Author(s)
  Katsutoshi Mizuno, Kei Shiozawa, Hiroshi Hamada.
- Organizer
  52nd Annual Meeting of the Japanese Society of Developmental Biologists
- Data Source
  KAKENHI-PROJECT-19K06753
[Presentation] 左右決定に関わるマウス胚ノード繊毛カルシウムシグナルの解析2018
- Author(s)
  水野克俊、塩澤啓、濱田博司
- Organizer
  第41回日本分子生物学会年会ワークショップ　繊毛が生み出すマルチスケールパターンを俯瞰する　ー　分子から組織・集団までのパターン形成
- Invited
- Data Source
  KAKENHI-PROJECT-17K15153
[Presentation] Visualization of ciliary Calcium influx that initiate mouse Left-Right asymmetry2018
- Author(s)
  Katsutoshi Mizuno, Kei Shiozawa, Hiroshi Hamada
- Organizer
  Joint Annual Meeting of JSDB 51st and JSCB 70th
- Data Source
  KAKENHI-PROJECT-17K15153
[Presentation] マウス胚ノード繊毛における、左右差を作り出すCa2+シグナルの可視化2017
- Author(s)
  水野克俊、塩澤啓、濱田博司
- Organizer
  第8回繊毛研究会
- Data Source
  KAKENHI-PROJECT-17K15153
[Presentation] Visualization of ciliary Calcium influx that initiate mouse Left-Right asymmetry2017
- Author(s)
  Katsutoshi Mizuno, Kei Shiozawa, Hiroshi Hamada
- Organizer
  The 50th annual meeting of JSDB
- Data Source
  KAKENHI-PROJECT-17K15153
[Presentation] Manipulation and Detection of Ca2+ Concentration Change of Single Immotile Cilium in Mammalian Node2017
- Author(s)
  加藤孝信、水野克俊、濱田博司、西坂崇之
- Organizer
  第 55 回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-17K15153
[Presentation] Visualization of ciliary Calcium influx that initiate mouse Left-Right asymmetry2017
- Author(s)
  水野克俊、塩澤啓、濱田博司
- Organizer
  兵庫県立こども病院-CDB 第 2 回ジョイントシンポジウム
- Data Source
  KAKENHI-PROJECT-17K15153

1. SHIBA Kogiku

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. INABA KAZUO

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Mizuno Katsutoshi 水野 克俊

Research Projects

Research Products

Co-Researchers

繊毛・鞭毛において新規に見出されたタンパク質メチル化の機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

神経軸索性インポーチンによる細胞質ダイニン制御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional analysis of nodal cilia derived calcium influx in left-right symmetry breakingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Visualization of ciliary Calcium that initiate Left-Right AsymmetryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Immotile cilia mechanically sense the direction of fluid flow for left-right determination2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Immotile cilia of the mouse node sense a fluid flow?induced mechanical force for left-right symmetry breaking2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Planar cell polarity?dependent asymmetric organization of microtubules for polarized positioning of the basal body in node cells2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] CFAP45 deficiency causes situs abnormalities and asthenospermia by disrupting an axonemal adenine nucleotide homeostasis module2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Role of Ca2+ transients at the node of the mouse embryo in breaking of left-right symmetry2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nodal paralogues underlie distinct mechanisms for visceral left-right asymmetry in reptiles and mammals2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ciliogenesis‐coupled accumulation of IFT‐B proteins in a novel cytoplasmic compartment2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 体の左右非対称性決定におけるノード繊毛とカルシウムの機能2018

Author(s)

Journal Title

Data Source

[Journal Article] Crystal structure of a Ca2+-dependent regulator of flagellar motility reveals the open-closed structural transition2018

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Calaxin establishes basal body orientation and coordinates movement of monocilia in sea urchin embryos2017

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Protein arginine methyltransferases interact with intraflagellar transport particles and change location during flagellar growth and resorption2017

Mizuno Katsutoshi 水野克俊

[Presentation] マウスノード不動繊毛は変形の向きを感知して左右軸を決定する: 非対称性を生み出すメカニカルな機構2022