ROKUTAN Hirofumi 六反啓文

Researcher Number	00782559
Affiliation (Current)	2025: 地方独立行政法人東京都健康長寿医療センター, 東京都健康長寿医療センター病院, 医長
Affiliation (based on the past Project Information) *help	2023: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究員 2019 – 2022: 東京大学, 医学部附属病院, 助教 2018: 国立研究開発法人国立がん研究センター, 研究所, 特任研究員
Review Section/Research Field	Principal Investigator Basic Section 49020:Human pathology-related / Basic Section 50010:Tumor biology-related
Keywords	Principal Investigator DNAシークエンス / 分化状態 / 悪性度 / 腺窩上皮 / 固有腺 / 胃型 / コピー数解析 / 進行胃癌 / 胃粘液癌 / 早期胃型腫瘍 … More / MUC5AC / 腺窩上皮分化 / マイクロサテライト不安定性 / 治療標的分子 / ゲノム解析 / MLH1 / RNAシークエンス / por1 / 低分化腺癌 / 胃癌 / 分子サブタイプ / FISH / リンパ節転移 / 遺伝子増幅 / p53 / SWI/SNF / 充実性増殖 / 悪性化機構 / シークエンス解析 / がんゲノム / dysplasia / ドライバー変異 / 初期変異 / 体細胞変異 / ARID2 / APC / 悪性化 / 胃腺腫 / 胃腫瘍 Less

固有腺・胃型上皮分化を示す胃腫瘍群の悪性度指標および遺伝子変異の包括的研究Principal Investigator
- Principal Investigator
  
  六反啓文
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
  The University of Tokyo
Genomic and pathological analysis towards classification of solid-type poorly differentiated gastric carcinomaPrincipal Investigator
- Principal Investigator
  
  ROKUTAN Hirofumi
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  The University of Tokyo
Genetic events relevant to cancerous progression from gastric adenoma or neoplasia with low-grade atypiaPrincipal Investigator
- Principal Investigator
  
  ROKUTAN Hirofumi
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  The University of Tokyo
  National Cancer Center Japan

All 2024 2023 2020 2019 2018

All Journal Article Presentation

[Journal Article] Multiancestry genomic and transcriptomic analysis of gastric cancer2023
- Author(s)
  Totoki Y, Saito-Adachi M, Shiraishi Y, Komura D, Nakamura H, Suzuki A, Tatsuno K, Rokutan H, Hama N, Yamamoto S, Ono H, Arai Y, Hosoda F, Katoh H, et al.
- Journal Title
  
  Nature Genetics
  
  Volume: 55 Issue: 4 Pages: 581-594
- DOI
  10.1038/s41588-023-01333-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06937, KAKENHI-PROJECT-22H04990, KAKENHI-PROJECT-19H01031, KAKENHI-PROJECT-20K07378, KAKENHI-PROJECT-21K06882, KAKENHI-PROJECT-20KK0174, KAKENHI-PLANNED-19H05744, KAKENHI-ORGANIZER-22H05021, KAKENHI-PROJECT-23K21431
[Journal Article] 胃：低分化腺癌，充実型および非充実型2020
- Author(s)
  六反啓文 , 牛久哲男
- Journal Title
  
  胃と腸
  
  Volume: 55 Pages: 408-411
- Data Source
  KAKENHI-PROJECT-20K16191
[Journal Article] Initial and crucial genetic events in intestinal-type gastric intramucosal neoplasia2019
- Author(s)
  Rokutan Hirofumi、Abe Hiroyuki、Nakamura Hiromi、Ushiku Tetsuo、Arakawa Erika、Hosoda Fumie、Yachida Shinichi、Tsuji Yosuke、Fujishiro Mitsuhiro、Koike Kazuhiko、Totoki Yasushi、Fukayama Masashi、Shibata Tatsuhiro
- Journal Title
  
  The Journal of Pathology
  
  Volume: 247 Issue: 4 Pages: 494-504
- DOI
  10.1002/path.5208
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06983, KAKENHI-PROJECT-26253021, KAKENHI-PROJECT-18K15229
[Presentation] 低異型度の腺窩上皮型腫瘍から胃粘液癌への進展に関する病理学的検討2024
- Author(s)
  六反啓文，新井冨生，石渡俊行，牛久哲男．
- Organizer
  第96回日本胃癌学会総会
- Data Source
  KAKENHI-PROJECT-22K06937
[Presentation] 早期胃型腫瘍から粘液癌への進展についての病理学的検討2023
- Author(s)
  六反啓文，新井冨生，石渡俊行，牛久哲男．
- Organizer
  第34回日本消化器癌発生学会総会
- Data Source
  KAKENHI-PROJECT-22K06937
[Presentation] Initial mutations in well-differentiated intramucosal neoplasias of the stomach （分化型の胃粘膜内腫瘍における初期体細胞変異）2019
- Author(s)
  六反啓文，阿部浩幸，中村浩実，牛久哲男，細田文恵，谷内田真一，辻陽介，藤城光弘，小池和彦，十時泰，深山正久，柴田龍弘
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K15229
[Presentation] Deep sequencing uncovered initial and fate-determining mutations in well-differentiated neoplasias of the stomach2019
- Author(s)
  Hirofumi Rokutan, Tetsuo Ushiku, Hiroyuki Abe, Hiromi Nakamura, Fumie Hosoda, Masashi Fukayama, Tatsuhiro Shibata
- Organizer
  38th Sapporo International Cancer Symposium
- Data Source
  KAKENHI-PROJECT-18K15229
[Presentation] 早期胃がんのゲノム解析2018
- Author(s)
  六反啓文，阿部浩幸，中村浩実，牛久哲男，荒川えりか，細田文恵，谷内田真一，辻陽介，藤城光弘，小池和彦，十時泰，深山正久，柴田龍弘
- Organizer
  第29回日本消化器癌発生学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18K15229

1. USHIKU Tetsuo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ROKUTAN Hirofumi 六反 啓文

Research Projects

Research Products

Co-Researchers

固有腺・胃型上皮分化を示す胃腫瘍群の悪性度指標および遺伝子変異の包括的研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Genomic and pathological analysis towards classification of solid-type poorly differentiated gastric carcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Genetic events relevant to cancerous progression from gastric adenoma or neoplasia with low-grade atypiaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Multiancestry genomic and transcriptomic analysis of gastric cancer2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 胃：低分化腺癌，充実型および非充実型2020

Author(s)

Journal Title

Data Source

[Journal Article] Initial and crucial genetic events in intestinal-type gastric intramucosal neoplasia2019

Author(s)

Journal Title

DOI

Data Source

[Presentation] 低異型度の腺窩上皮型腫瘍から胃粘液癌への進展に関する病理学的検討2024

Author(s)

Organizer

Data Source

[Presentation] 早期胃型腫瘍から粘液癌への進展についての病理学的検討2023

Author(s)

Organizer

Data Source

[Presentation] Initial mutations in well-differentiated intramucosal neoplasias of the stomach （分化型の胃粘膜内腫瘍における初期体細胞変異）2019

Author(s)

Organizer

Data Source

[Presentation] Deep sequencing uncovered initial and fate-determining mutations in well-differentiated neoplasias of the stomach2019

Author(s)

Organizer

Data Source

[Presentation] 早期胃がんのゲノム解析2018

Author(s)

Organizer

Data Source

ROKUTAN Hirofumi 六反啓文