Fukaya Takashi 深谷雄志

Researcher Number	00786163
Other IDs	https://orcid.org/0000-0003-1478-6860
Affiliation (Current)	2025: 東京大学, 定量生命科学研究所, 教授
Affiliation (based on the past Project Information) *help	2021 – 2025: 東京大学, 定量生命科学研究所, 准教授 2018 – 2020: 東京大学, 定量生命科学研究所, 講師
Review Section/Research Field	Principal Investigator Transformative Research Areas, Section (III) / Biological Sciences / Basic Section 43010:Molecular biology-related / Medium-sized Section 43:Biology at molecular to cellular levels, and related fields / 0701:Biology at molecular to cellular levels, and related fields
Keywords	Principal Investigator エンハンサー / 転写 / ショウジョウバエ / ライブイメージング / 初期胚発生 / ゲノム構造 / 初期発生 / インシュレーター / 転写因子 / 転写バースト … More / 転写制御 / ショウジョウバエ初期胚 / 非コードRNA / eRNA / enhancer RNA / RNA / ゲノムトポロジー / TAD / 初期胚 / コアプロモーター / 天然変性領域 / プロモーター / パイオニア因子 / デグロン / プロテインノックダウン / ゲノム編集 / オプトジェネティクス Less

超解像イメージングと大規模定量技術による転写因子動作原理の解明Principal Investigator
- Principal Investigator
  
  深谷雄志
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  The University of Tokyo
初期発生運命を司る動的転写エピコードの解読Principal Investigator
- Principal Investigator
  
  深谷雄志
- Project Period (FY)
  2024 – 2028
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  The University of Tokyo
ゲノム構造と転写のクロストークを生み出す動的制御基盤の解明Principal Investigator
- Principal Investigator
  
  深谷雄志
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  The University of Tokyo
enhancer RNAを介した転写動態制御機構の解明Principal Investigator
- Principal Investigator
  
  深谷雄志
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43010:Molecular biology-related
- Research Institution
  The University of Tokyo
全能性消失時における新規エンハンサー作用機序の統合的理解Principal Investigator
- Principal Investigator
  
  深谷雄志
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
DNAループ形成動態のモダリティPrincipal Investigator
- Principal Investigator
  
  深谷雄志
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  The University of Tokyo
全能性消失時のゲノム構造変化に連動した転写制御機構の解明Principal Investigator
- Principal Investigator
  
  深谷雄志
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Developing light inducible degron system in DrosophilaPrincipal Investigator
- Principal Investigator
  
  Fukaya Takashi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  The University of Tokyo
Elucidating transcriptional dynamics control via the formation of nuclear microenvironmentsPrincipal Investigator
- Principal Investigator
  
  Fukaya Takashi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43010:Molecular biology-related
- Research Institution
  The University of Tokyo
パイオニア因子によるエンハンサー制御機構の解明Principal Investigator
- Principal Investigator
  
  深谷雄志
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0701:Biology at molecular to cellular levels, and related fields
- Research Institution
  The University of Tokyo

All 2024 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] Regulatory landscape of enhancer-mediated transcriptional activation2024
- Author(s)
  Kawasaki Koji、Fukaya Takashi
- Journal Title
  
  Trends in Cell Biology
  
  Volume: - Issue: 10 Pages: 826-837
- DOI
  10.1016/j.tcb.2024.01.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22KJ0760, KAKENHI-PUBLICLY-22H04665
[Journal Article] Enhancer dynamics: Unraveling the mechanism of transcriptional bursting2023
- Author(s)
  Fukaya Takashi
- Journal Title
  
  Science Advances
  
  Volume: 9 Issue: 31
- DOI
  10.1126/sciadv.adj3366
- Open Access
- Data Source
  KAKENHI-PUBLICLY-22H04665
[Journal Article] Dynamic interplay between non-coding enhancer transcription and gene activity in development2023
- Author(s)
  Hamamoto Kota、Umemura Yusuke、Makino Shiho、Fukaya Takashi
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 826-826
- DOI
  10.1038/s41467-023-36485-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-19H05749, KAKENHI-PUBLICLY-22H04665, KAKENHI-PUBLICLY-21H05742, KAKENHI-PROJECT-23K23808
[Journal Article] Functional coordination between transcription factor clustering and gene activity2023
- Author(s)
  Kawasaki Koji、Fukaya Takashi
- Journal Title
  
  Molecular Cell
  
  Volume: 83 Issue: 10 Pages: 1605-1622.e9
- DOI
  10.1016/j.molcel.2023.04.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22KJ0760, KAKENHI-PUBLICLY-22H04665
[Journal Article] Molecular architecture of enhancer-promoter interaction2022
- Author(s)
  Hamamoto Kota、Fukaya Takashi
- Journal Title
  
  Current Opinion in Cell Biology
  
  Volume: 74 Pages: 62-70
- DOI
  10.1016/j.ceb.2022.01.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22378
[Journal Article] Mod(mdg4) variants repress telomeric retrotransposon HeT-A by blocking subtelomeric enhancers2022
- Author(s)
  Chikara Takeuchi, Moe Yokoshi, Shu Kondo, Aoi Shibuya, Kuniaki Saito, Takashi Fukaya, Haruhiko Siomi, Yuka W Iwasaki
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 50 Issue: 20 Pages: 11580-11599
- DOI
  10.1093/nar/gkac1034
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-20H03246, KAKENHI-PROJECT-22KJ2696, KAKENHI-PROJECT-19H03154, KAKENHI-ORGANIZER-19H05749, KAKENHI-PLANNED-19H05753, KAKENHI-PUBLICLY-21H00259, KAKENHI-PUBLICLY-20H05357, KAKENHI-PROJECT-23K23811, KAKENHI-PUBLICLY-22H04665, KAKENHI-PUBLICLY-21H05742, KAKENHI-PROJECT-23K23808
[Journal Article] Dynamic regulation of anterior-posterior patterning genes in living Drosophila embryos2021
- Author(s)
  Fukaya Takashi
- Journal Title
  
  Current Biology
  
  Volume: 未定 Issue: 10 Pages: 2227-2236.e6
- DOI
  10.1016/j.cub.2021.02.050
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22378, KAKENHI-PUBLICLY-20H05357, KAKENHI-PROJECT-19H03154
[Journal Article] Dynamic modulation of enhancer responsiveness by core promoter elements in living <i>Drosophila</i> embryos2021
- Author(s)
  Yokoshi Moe、Kawasaki Koji、Camb?n Manuel、Fukaya Takashi
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 50 Issue: 1 Pages: 92-107
- DOI
  10.1093/nar/gkab1177
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22378, KAKENHI-PROJECT-21K20627, KAKENHI-ORGANIZER-19H05749, KAKENHI-PROJECT-20K15710, KAKENHI-PROJECT-19H03154, KAKENHI-PUBLICLY-20H05357
[Journal Article] Visualizing the Role of Boundary Elements in Enhancer-Promoter Communication2020
- Author(s)
  Moe Yokoshi, Kazuma Segawa, Takashi Fukaya
- Journal Title
  
  Molecular Cell
  
  Volume: VOLUME 78, ISSUE 2 Issue: 2 Pages: 224-235
- DOI
  10.1016/j.molcel.2020.02.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22378, KAKENHI-PROJECT-19H03154
[Presentation] ハブの形成を介した転写バースト制御2024
- Author(s)
  深谷雄志
- Organizer
  ABiSシンポジウム「イメージングデータ解析が拓く生命科学の新時代」
- Invited
- Data Source
  KAKENHI-PUBLICLY-22H04665
[Presentation] Dynamics of transcription hubs in living Drosophila embryos2023
- Author(s)
  深谷雄志
- Organizer
  The 3rd NINS-Princeton Joint Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-21H05742
[Presentation] Visualization of transcription hubs in living Drosophila embryos2023
- Author(s)
  深谷雄志
- Organizer
  The 2nd International Symposium on REPLICATION of Non-Genome
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-22H04665
[Presentation] Dynamics of transcription hubs in living Drosophila embryos2023
- Author(s)
  深谷雄志
- Organizer
  The 3rd NINS-Princeton Joint Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-22H04665
[Presentation] Dynamics of transcription hubs in living Drosophila embryos2023
- Author(s)
  深谷雄志
- Organizer
  The 3rd NINS-Princeton Joint Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K23808
[Presentation] 相分離した生体分子が織りなす巧みな遺伝子発現制御2023
- Author(s)
  深谷雄志
- Organizer
  CSJ化学フェスタ
- Invited
- Data Source
  KAKENHI-PUBLICLY-22H04665
[Presentation] Enhancer dynamics in living embryos2023
- Author(s)
  深谷雄志
- Organizer
  Annual Meeting of the Molecular Biology Society of Japan
- Invited
- Data Source
  KAKENHI-PUBLICLY-22H04665
[Presentation] Enhancer dynamics in living embryos2023
- Author(s)
  深谷雄志
- Organizer
  UTokyo-KI LINK Kick Off Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-22H04665
[Presentation] Dynamics of transcription hubs in living Drosophila embryos2023
- Author(s)
  Takashi Fukaya
- Organizer
  The 3rd NINS-Princeton Joint Symposium EMERGING LIFE SCIENCES
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-21H05742
[Presentation] Enhancer dynamics in living embryos2023
- Author(s)
  深谷雄志
- Organizer
  RIKEN Symposium "Architecture and Function of Biological Assemblies"
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-22H04665
[Presentation] Visualization of transcription hubs in living Drosophila embryos2023
- Author(s)
  深谷雄志
- Organizer
  CSHL meeting Mechanisms of Eukaryotic Transcription
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-22H04665
[Presentation] Visualization of transcription hubs in living Drosophila embryos2023
- Author(s)
  深谷雄志
- Organizer
  International conference on biological physics
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-22H04665
[Presentation] Transcription dynamics in living Drosophila embryos2021
- Author(s)
  Takashi Fukaya
- Organizer
  The 1st ASHBi SignAC workshop
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H05357
[Presentation] Transcription dynamics in living Drosophila embryos2021
- Author(s)
  Takashi Fukaya
- Organizer
  The 1st ASHBi SignAC workshop
- Invited
- Data Source
  KAKENHI-PROJECT-19K22378
[Presentation] Transcription dynamics in living Drosophila embryos2021
- Author(s)
  Takashi Fukaya
- Organizer
  JSDB/APDBN Symposium RNA, Stem Cells, Technology in Development
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03154
[Presentation] Transcription dynamics in living Drosophila embryos2021
- Author(s)
  Takashi Fukaya
- Organizer
  The 1st ASHBi SignAC workshop
- Invited
- Data Source
  KAKENHI-PROJECT-19H03154
[Presentation] Transcription dynamics in living Drosophila embryos2021
- Author(s)
  Takashi Fukaya
- Organizer
  JSDB/APDBN Symposium RNA, Stem Cells, Technology in Development
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-20H05357
[Presentation] Transcription dynamics in living Drosophila embryos2021
- Author(s)
  Takashi Fukaya
- Organizer
  JSDB/APDBN Symposium RNA, Stem Cells, Technology in Development
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22378
[Presentation] Regulation of transcriptional bursting by core promoter elements2020
- Author(s)
  Takashi Fukaya
- Organizer
  EMBL Conference Transcription and Chromatin
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03154
[Presentation] Regulation of transcriptional bursting in living Drosophila embryos2020
- Author(s)
  Takashi Fukaya
- Organizer
  日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03154
[Presentation] Regulation of transcriptional bursting in living Drosophila embryos2020
- Author(s)
  Takashi Fukaya
- Organizer
  日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03154
[Presentation] Regulation of transcriptional bursting in living Drosophila embryos2020
- Author(s)
  Takashi Fukaya
- Organizer
  日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22378
[Presentation] Regulation of transcriptional bursting by core promoter elements2020
- Author(s)
  Takashi Fukaya
- Organizer
  EMBL Conference Transcription and Chromatin
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-20H05357
[Presentation] Regulation of transcriptional bursting in living Drosophila embryos2020
- Author(s)
  Takashi Fukaya
- Organizer
  日本生化学会大会
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H05357
[Presentation] Regulation of transcriptional bursting in living Drosophila embryos2020
- Author(s)
  Takashi Fukaya
- Organizer
  日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H05357
[Presentation] Regulation of transcriptional bursting in living Drosophila embryos2020
- Author(s)
  Takashi Fukaya
- Organizer
  日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22378
[Presentation] topological regulation of enhancer-promoter communication2019
- Author(s)
  Takashi Fukaya
- Organizer
  日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03154
[Presentation] topological regulation of transcriptional bursting2019
- Author(s)
  Takashi Fukaya
- Organizer
  日本遺伝学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03154
[Presentation] topological regulation of transcriptional bursting2019
- Author(s)
  Takashi Fukaya
- Organizer
  第４回定量生命科学研究所シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-19H03154
[Presentation] topological regulation of transcriptional bursting2019
- Author(s)
  Takashi Fukaya
- Organizer
  日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03154
[Presentation] Topological regulation of transcriptional bursting2019
- Author(s)
  深谷雄志
- Organizer
  第４回定量生命科学研究所シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-18H06040
[Presentation] topological regulation of transcriptional bursting2019
- Author(s)
  Takashi Fukaya
- Organizer
  NIBB-Princeton Joint Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03154

1. 篠原隆司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Fukaya Takashi 深谷 雄志

Research Projects

Research Products

Co-Researchers

超解像イメージングと大規模定量技術による転写因子動作原理の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

初期発生運命を司る動的転写エピコードの解読Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ゲノム構造と転写のクロストークを生み出す動的制御基盤の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

enhancer RNAを介した転写動態制御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

全能性消失時における新規エンハンサー作用機序の統合的理解Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

DNAループ形成動態のモダリティPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

全能性消失時のゲノム構造変化に連動した転写制御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Developing light inducible degron system in DrosophilaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidating transcriptional dynamics control via the formation of nuclear microenvironmentsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

パイオニア因子によるエンハンサー制御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Regulatory landscape of enhancer-mediated transcriptional activation2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Enhancer dynamics: Unraveling the mechanism of transcriptional bursting2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dynamic interplay between non-coding enhancer transcription and gene activity in development2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Functional coordination between transcription factor clustering and gene activity2023

Fukaya Takashi 深谷雄志