Yamahashi Yukie 山橋幸恵

Researcher Number	00793481
Other IDs	https://orcid.org/0000-0003-3697-0861
Affiliation (Current)	2025: 藤田医科大学, 医科学研究センター, 助教
Affiliation (based on the past Project Information) *help	2023 – 2024: 藤田医科大学, 医科学研究センター, 助教 2020 – 2021: 藤田医科大学, 総合医科学研究所, 助教 2019: 名古屋大学, 医学系研究科, 研究員
Review Section/Research Field	Principal Investigator Basic Section 47040:Pharmacology-related Except Principal Investigator Basic Section 46030:Function of nervous system-related
Keywords	Principal Investigator シグナル伝達 / PAKキナーゼ / アセチルコリン / 低分子量G蛋白Rac1 / アルツハイマー病 / Rac1 / ムスカリン受容体M1R / 学習・記憶障害 / リン酸化プロテオミクス / D2R-MSN … More / PKC / スパイン / リン酸化 / PAK / 忌避学習・嫌悪記憶 / 認知記憶 / 海馬 / 側坐核 / シナプス / 認知機能 / 忌避学習 / ドネペジル … More Except Principal Investigator 学習 / 情動 / 全脳イメージング / リン酸化シグナル / ニューロモジュレーター Less

ニューロモデュレーターとリン酸化シグナルによる情動と学習の制御機構の解明
- Principal Investigator
  
  貝淵弘三
- Project Period (FY)
  2024 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 46030:Function of nervous system-related
- Research Institution
  Fujita Health University
Acetylcholine-dependent signal transduction in Alzheimer's disease pathologyPrincipal Investigator
- Principal Investigator
  
  山橋幸恵
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Fujita Health University
The clarification of acetylcholine-PAK signaling in aversive learning and cognitive memory formationPrincipal Investigator
- Principal Investigator
  
  Yamahashi Yukie
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Fujita Health University
  Nagoya University

All 2024 2023 2021 2020 2019 2018

All Journal Article Presentation

[Journal Article] 忌避行動学習におけるアセチルコリンの神経細胞内シグナル伝達機構2024
- Author(s)
  山橋幸恵, 貝淵弘三
- Journal Title
  
  BioClinica
  
  Volume: 39 Pages: 52-55
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K06173
[Journal Article] Neuroproteomic mapping of kinases and their substrates downstream of acetylcholine: finding and implications2023
- Author(s)
  Yamahashi Y, Tsuboi D, Funahashi Y, Kaibuchi K.
- Journal Title
  
  Expert Rev Proteomics
  
  Volume: 20 Issue: 11 Pages: 291-298
- DOI
  10.1080/14789450.2023.2265067
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06427, KAKENHI-PROJECT-23K06173
[Journal Article] The Evaluation of Rac1 Signaling as a Potential Therapeutic Target of Alzheimer’s Disease2023
- Author(s)
  Wang Huanhuan、Yamahashi Yukie、Riedl Marcel、Amano Mutsuki、Kaibuchi Kozo
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 15 Pages: 11880-11880
- DOI
  10.3390/ijms241511880
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06173
[Journal Article] KANPHOS: A Database of Kinase-Associated Neural Protein Phosphorylation in the Brain2021
- Author(s)
  Ahammad Rijwan Uddin、Nishioka Tomoki、Yoshimoto Junichiro、Kannon Takayuki、Amano Mutsuki、Funahashi Yasuhiro、Tsuboi Daisuke、Faruk Md. Omar、Yamahashi Yukie、Yamada Kiyofumi、Nagai Taku、Kaibuchi Kozo
- Journal Title
  
  Cells
  
  Volume: 11 Issue: 1 Pages: 47-47
- DOI
  10.3390/cells11010047
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16370, KAKENHI-PUBLICLY-21H00196, KAKENHI-PROJECT-21K06427, KAKENHI-PROJECT-21K06428
[Journal Article] Muscarinic signaling regulates voltage‐gated potassium channel KCNQ2 phosphorylation in the nucleus accumbens via protein kinase C for aversive learning2021
- Author(s)
  Faruk Md. Omar、Tsuboi Daisuke、Yamahashi Yukie、Funahashi Yasuhiro、Lin You‐Hsin、Ahammad Rijwan Uddin、Hossen Emran、Amano Mutsuki、Nishioka Tomoki、Tzingounis Anastasios V、Yamada Kiyofumi、Nagai Taku、Kaibuchi Kozo
- Journal Title
  
  Journal of Neurochemistry
  
  Volume: 160 Issue: 3 Pages: 325-341
- DOI
  10.1111/jnc.15555
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16370, KAKENHI-PUBLICLY-21H00196, KAKENHI-PROJECT-21K06427, KAKENHI-PROJECT-21K06428, KAKENHI-PROJECT-20K07082
[Journal Article] Accumbal D2R-medium spiny neurons regulate aversive behaviors through PKA-Rap1 pathway.2020
- Author(s)
  Lin, Y-H., Yamahashi, Y., Kuroda, K., Faruk M. O., Zhang, X., Yamada, K., Yamanaka, A., Nagai, T., Kaibuchi, K.
- Journal Title
  
  Neurocham. Int.
  
  Volume: 143 Pages: 104935-104935
- DOI
  10.1016/j.neuint.2020.104935
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07082, KAKENHI-PROJECT-20K07965, KAKENHI-PROJECT-18K14816, KAKENHI-PROJECT-19K16370, KAKENHI-PROJECT-18KK0223, KAKENHI-PUBLICLY-19H05016, KAKENHI-PUBLICLY-19H05209, KAKENHI-PUBLICLY-20H05061, KAKENHI-PROJECT-17H01380, KAKENHI-PROJECT-18H02523, KAKENHI-PROJECT-19K23774
[Journal Article] Comprehensive analysis of kinase-oriented phospho-signalling pathways2018
- Author(s)
  Amano Mutsuki、Nishioka Tomoki、Tsuboi Daisuke、Kuroda Keisuke、Funahashi Yasuhiro、Yamahashi Yukie、Kaibuchi Kozo
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 165 Issue: 4 Pages: 301-307
- DOI
  10.1093/jb/mvy115
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K14816, KAKENHI-PUBLICLY-17H05561, KAKENHI-PROJECT-17H01380, KAKENHI-PROJECT-15K06772, KAKENHI-PROJECT-16K18393, KAKENHI-PROJECT-19K16370, KAKENHI-PROJECT-17K07383
[Presentation] Acetylcholine-dependent Signal Transduction Leading to Aversive Learning2023
- Author(s)
  山橋　幸恵
- Organizer
  Fujita International Symposium on Brain Science 2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06173
[Presentation] Phosphoproteomic of acetylcholine-PKC signaling in the brain: a platform for developing Alzheimer’s disease therapeutic strategies2023
- Author(s)
  Yukie Yamahashi
- Organizer
  FASEB
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06173
[Presentation] 忌避行動学習におけるアセチルコリンの細胞内シグナル伝達機構2023
- Author(s)
  山橋　幸恵
- Organizer
  第64回日本神経病理学会総会学術研究会/第66回日本神経化学会大会合同大会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06173
[Presentation] 忌避学習に至るアセチルコリンシグナル伝達の解明2021
- Author(s)
  山橋　幸恵
- Organizer
  2021年度若手支援技術講習会
- Data Source
  KAKENHI-PROJECT-19K16370
[Presentation] Acetylcholine signaling in D2R-MSN neurons and its stimulation of aversive learning2021
- Author(s)
  Yamahashi Y., Lin Y.H., Iwanaga S., Kawashima T., Tokumoto Y., Faruk O., Zhang X., Nagai T., Tsuboi D., Kaibuchi K.
- Organizer
  第64回日本神経化学会大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16370
[Presentation] 忌避学習に至るアセチルコリンシグナル伝達の解明2021
- Author(s)
  山橋幸恵、張　心健、永井　拓、坪井　大輔、貝淵弘三
- Organizer
  第53回藤田学園医学会
- Data Source
  KAKENHI-PROJECT-19K16370
[Presentation] Acetylcholine signaling in D2R-MSN neurons and its stimulation of aversive learning2020
- Author(s)
  Yukie Yamahashi, You-Shin Lin, Sho Iwanaga, Tomohiro Kawashima, Yuya Tokumoto, Omar Faruk, Xijian Zhang, Taku Nagai, Daisuke Tsuboi, Kozo Kaibuchi
- Organizer
  総合医科学研究所・研究成果発表会
- Data Source
  KAKENHI-PROJECT-19K16370
[Presentation] 忌避行動・学習に至る側坐核内のアセチルコリンの作用機序2019
- Author(s)
  山橋幸恵、岩永渉、徳元友哉、林祐新、張心健、永井拓、坪井大輔、貝淵弘三
- Organizer
  第３４回　日本大脳基底核研究会
- Data Source
  KAKENHI-PROJECT-19K16370
[Presentation] 嫌悪刺激によるドーパミン放出の抑制が側坐核D2R-中型有棘神経細胞内のPKA-Rap1経路を活性化する2019
- Author(s)
  林祐新、永井拓、山橋幸恵、黒田啓介、貝淵弘三
- Organizer
  Neuro2019 第42回日本神経科学大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16370
[Presentation] 側坐核D2R-中型有棘神経細胞内におけるアデノシン-A2AR-PKA-Rap1経路が忌避行動を制御する2019
- Author(s)
  林祐新、永井拓、山橋幸恵、黒田啓介、貝淵弘三
- Organizer
  第９回　名古屋大学医学系研究科・生理研究所合同シンポジウム
- Data Source
  KAKENHI-PROJECT-19K16370
[Presentation] 忌避行動・学習に至る側坐核内のアセチルコリンの作用機序2019
- Author(s)
  山橋幸恵、岩永渉、徳元友哉、林祐新、張心健、永井拓、坪井大輔、貝淵弘三
- Organizer
  Neuro2019 第42回日本神経科学大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16370

1. 貝淵弘三 (00169377)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 船橋靖広 (00749913)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 坪井大輔 (80584672)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 黒田啓介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 永井拓

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yamahashi Yukie 山橋 幸恵

Research Projects

Research Products

Co-Researchers

ニューロモデュレーターとリン酸化シグナルによる情動と学習の制御機構の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Acetylcholine-dependent signal transduction in Alzheimer's disease pathologyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The clarification of acetylcholine-PAK signaling in aversive learning and cognitive memory formationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] 忌避行動学習におけるアセチルコリンの神経細胞内シグナル伝達機構2024

Author(s)

Journal Title

Data Source

[Journal Article] Neuroproteomic mapping of kinases and their substrates downstream of acetylcholine: finding and implications2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Evaluation of Rac1 Signaling as a Potential Therapeutic Target of Alzheimer’s Disease2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] KANPHOS: A Database of Kinase-Associated Neural Protein Phosphorylation in the Brain2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Muscarinic signaling regulates voltage‐gated potassium channel KCNQ2 phosphorylation in the nucleus accumbens via protein kinase C for aversive learning2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Accumbal D2R-medium spiny neurons regulate aversive behaviors through PKA-Rap1 pathway.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Comprehensive analysis of kinase-oriented phospho-signalling pathways2018

Author(s)

Journal Title

DOI

Data Source

[Presentation] Acetylcholine-dependent Signal Transduction Leading to Aversive Learning2023

Author(s)

Organizer

Data Source

[Presentation] Phosphoproteomic of acetylcholine-PKC signaling in the brain: a platform for developing Alzheimer’s disease therapeutic strategies2023

Author(s)

Organizer

Data Source

[Presentation] 忌避行動学習におけるアセチルコリンの細胞内シグナル伝達機構2023

Author(s)

Organizer

Data Source

[Presentation] 忌避学習に至るアセチルコリンシグナル伝達の解明2021

Author(s)

Organizer

Data Source

[Presentation] Acetylcholine signaling in D2R-MSN neurons and its stimulation of aversive learning2021

Author(s)

Organizer

Data Source

[Presentation] 忌避学習に至るアセチルコリンシグナル伝達の解明2021

Author(s)

Organizer

Data Source

Yamahashi Yukie 山橋幸恵