HAYASHI YOSHIKAZU 林慶和

… Alternative Names

Hayashi Yoshikazu 林慶和

Less

Researcher Number	00801078
Other IDs
Affiliation (Current)	2025: 福岡歯科大学, 口腔歯学部, 講師
Affiliation (based on the past Project Information) *help	2023 – 2025: 福岡歯科大学, 口腔歯学部, 講師 2020 – 2022: 福岡歯科大学, 口腔歯学部, 助教 2019: 熊本大学, 国際先端医学研究機構, 特任助教 2018: 熊本大学, 国際先端医学研究機構, 特定事業研究員
Review Section/Research Field	Principal Investigator Basic Section 54010:Hematology and medical oncology-related / Basic Section 57010:Oral biological science-related Except Principal Investigator Medium-sized Section 57:Oral science and related fields / Basic Section 57010:Oral biological science-related / Basic Section 57060:Surgical dentistry-related
Keywords	Principal Investigator 造血応答 / 自然免疫 / 腸内細菌 / 腸管炎症 / 多能性前駆細胞 / 造血幹細胞 / ミトコンドリア / がん代謝 / ACOD1 / TCA回路 … More / グルタチオン / 抗酸化 / イタコン酸 / 常在菌 / 炎症性疾患 / 慢性炎症 / 顆粒球 / 骨髄球 / 組織修復 / 造血幹前駆細胞 / 炎症性老化 / 造血幹・前駆細胞 / Gr-1細胞 / Bacteroides / 細胞遊走 / 細胞分化 / TLRシグナル … More Except Principal Investigator COVID-19 / IgG4関連疾患 / エネルギー代謝 / 肥満 / 栄養 / DOHaD / 免疫複合体 / 自己抗原 / 形質細胞 / 腫瘍 / 自己免疫疾患 / 自己抗体 / 木村氏病 / B細胞 / 濾胞性T細胞 / COVID19 / IgG4 / クラススイッチ / IgG4-related disease / autoimmune disesase / double negative B cell / ダブルネガティブB細胞 / 細胞障害性CD4+ヘルパーT細胞 / DN B細胞 / CD4+CTLs Less

胎内栄養環境が規定する成熟後の肥満・異所性脂肪蓄積の素因形成メカニズム
- Principal Investigator
  
  安河内友世 (川久保友世)
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Kyushu University
疾患特異的環境下における自己抗体産生B 細胞とその抗原の同定
- Principal Investigator
  
  金子直樹
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Kyushu University
がん進展におけるACOD1およびイタコン酸の機能解析Principal Investigator
- Principal Investigator
  
  林慶和
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Fukuoka Dental College
The mechanisms of class switching in IgG4-related disease, Kimura's disease and COVID-19
- Principal Investigator
  
  金子直樹
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Kyushu University
Expansion of CD4+ cytotoxic T lymphocytes and IgD-CD27- double negative B cells in COVID-19 and autoimmune diseases including IgG4-related disease
- Principal Investigator
  
  金子直樹
- Project Period (FY)
  2021 – 2026
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Kyushu University
Understanding the cross-organ communication on hematopoiesis regulated via gut microbiota signalingPrincipal Investigator
- Principal Investigator
  
  Hayashi Yoshikazu
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Fukuoka Dental College
Understanding the impact of gut inflammation-induced stress on hematopoiesisPrincipal Investigator
- Principal Investigator
  
  Hayashi Yoshikazu
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kumamoto University

All 2024 2023 2022 2021 2020 2019 2018

All Journal Article Presentation

[Journal Article] Id4 modulates salivary gland homeostasis and its expression is downregulated in IgG4-related disease via miR-486-5p2023
- Author(s)
  1.Hayashi Y, Kimura S, Yano E, Yoshimoto S, Saeki A, Yasukochi A, Hatakeyama Y, Moriyama M, Nakamura S, Jimi E, Kawakubo-Yasukochi T.
- Journal Title
  
  Biochim Biophys Acta Mol Cell Res
  
  Volume: 1870(2) Issue: 2 Pages: 119404-119404
- DOI
  10.1016/j.bbamcr.2022.119404
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09914, KAKENHI-PROJECT-22K10173, KAKENHI-PROJECT-22K19631, KAKENHI-PROJECT-22K17003, KAKENHI-PROJECT-20K17381, KAKENHI-PROJECT-22K18401, KAKENHI-PROJECT-19K22723, KAKENHI-PROJECT-23KK0164, KAKENHI-PROJECT-21K10075
[Journal Article] Hematopoietic stem and progenitor cells integrate microbial signals to promote post‐inflammation gut tissue repair2022
- Author(s)
  Sezaki Maiko、Hayashi Yoshikazu、Nakato Gaku、Wang Yuxin、Nakata Sayuri、Biswas Subinoy、Morishima Tatsuya、Fakruddin Md、Moon Jieun、Ahn Soyeon、Kim Pilhan、Miyamoto Yuji、Baba Hideo、Fukuda Shinji、Takizawa Hitoshi
- Journal Title
  
  The EMBO Journal
  
  Volume: 41 Issue: 22
- DOI
  10.15252/embj.2022110712
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08397, KAKENHI-PROJECT-20K17381
[Journal Article] iPSC-Derived Platelets Depleted of HLA Class I Are Inert to Anti-HLA Class I and Natural Killer Cell Immunity.2020
- Author(s)
  Suzuki D, Flahou C, Yoshikawa N, Stirblyte I, Hayashi Y, Sawaguchi A, Akasaka M, Nakamura S, Higashi N, Xu H, Matsumoto T, Fujio K, Manz MG, Hotta A, Takizawa H, Eto K, Sugimoto N.
- Journal Title
  
  Stem Cell Reports.
  
  Volume: 14 Issue: 1 Pages: 49-59
- DOI
  10.1016/j.stemcr.2019.11.011
- NAID
  120006777032
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22675, KAKENHI-PROJECT-18H04164, KAKENHI-PROJECT-18K16091
[Journal Article] Immuno-Modulation of Hematopoietic Stem and Progenitor Cells in Inflammation2020
- Author(s)
  Sezaki Maiko、Hayashi Yoshikazu、Wang Yuxin、Johansson Alban、Umemoto Terumasa、Takizawa Hitoshi
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 11 Pages: 585367-585367
- DOI
  10.3389/fimmu.2020.585367
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17381, KAKENHI-PROJECT-18J20690
[Journal Article] Innate immune signal-mediated regulation and alterations in hematopoiesis2020
- Author(s)
  林慶和、滝澤仁
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 61 Issue: 6 Pages: 651-656
- DOI
  10.11406/rinketsu.61.651
- NAID
  130007869131
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K17381
[Journal Article] Development of the Hematopoietic System: Role of Inflammatory Factors2019
- Author(s)
  Hayashi Y#, Sezaki M#, Takizawa H*
- Journal Title
  
  Wiley Interdiscip Rev Dev Biol
  
  Volume: 27 Issue: 4
- DOI
  10.1002/wdev.341
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-17H05651, KAKENHI-PROJECT-18H02843, KAKENHI-PROJECT-18J20690, KAKENHI-PROJECT-18K16091
[Journal Article] Inflammation and early hematopoiesis2018
- Author(s)
  滝澤仁、林慶和
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 59 Issue: 10 Pages: 1955-1961
- DOI
  10.11406/rinketsu.59.1955
- NAID
  130007496839
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-18K16091
[Presentation] イタコン酸によるがん細胞抗酸化システムの破綻2024
- Author(s)
  林慶和、佐伯彩華、吉本尚平3、畠山雄次、平田雅人、自見英治郎、安河内（川久保）友世
- Organizer
  第129回日本解剖学会全国学術集会
- Data Source
  KAKENHI-PROJECT-23K09133
[Presentation] The function of membrane-permeable itaconate in cancer cell growth2024
- Author(s)
  Ayaka Saeki, Yoshikazu Hayashi, Shohei Yoshimoto, Yuji Hatakeyama, Masato Hirata, Eijiro Jimi, Tomoyo Kawakubo-Yasukochi
- Organizer
  Kyudai Oral Bioscience & OBT Research Center・DDR Research Center 7th Joint International Symposium 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K09133
[Presentation] イタコン酸によるグルタチオン代謝異常に起因したがん細胞増殖抑制機構2023
- Author(s)
  林慶和
- Organizer
  OMシンポジウム2023
- Invited
- Data Source
  KAKENHI-PROJECT-23K09133
[Presentation] がん細胞増殖におけるイタコン酸の役割2023
- Author(s)
  佐伯彩華、林慶和、吉本尚平、畠山雄次、平田雅人、自見英治郎、安河内（川久保）友世
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K09133
[Presentation] イタコン酸によるがん細胞抗酸化システムの制御2023
- Author(s)
  佐伯彩華、林慶和、吉本尚平、畠山雄次、平田雅人、自見英治郎、安河内（川久保）友世
- Organizer
  第65回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-23K09133
[Presentation] Hematopoietic stem and progenitor cells integrate microbial signals to enhance gut tissue repair2021
- Author(s)
  Maiko Sezaki, Yoshikazu Hayashi, Gaku Nakato, Subinoy Biswas, Tatsuya Morishima, Jieun Moon, Soyeon Ahn, Pilhan Kim, Yuji Miyamoto, Hideo Baba, Shinji Fukuda and Hitoshi Takizawa
- Organizer
  18th Stem Cell Research Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17381
[Presentation] 慢性炎症は造血幹細胞の骨髄再構築能を低下させる2020
- Author(s)
  林　慶和
- Organizer
  第62回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-20K17381
[Presentation] タイトル：成人造血形成における造血幹細胞移行と骨髄リモデリングの時空間的供応2019
- Author(s)
  Sezaki M, Sham KYC, Hayashi Y, Haeno H, Yokomizo T, Nombela-Arrieta C, Laurenti E, Takizawa H
- Organizer
  第８１回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K16091
[Presentation] Microbial signal regulates crosstalk between bone marrow and other organs in early hematopoiesis2019
- Author(s)
  Hayashi Y
- Organizer
  The 3rd KU - KAIST Joint Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16091
[Presentation] Early hematopoiesis translates microbial signals to intestinal tissue repair2019
- Author(s)
  Hayashi Y, Takizawa H, Sezaki M, Sheoran S, Morishima T, Nakato G, Biswas S, Fukuda S.
- Organizer
  24th Congress of the European Hematology Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16091
[Presentation] 自然免疫シグナルは腸管炎症下における造血応答を制御する2019
- Author(s)
  Hayashi Y, Sezaki M, Nakato G, Sheoran S, Morishima T, Fukuda S, Takizawa H.
- Organizer
  第８１回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K16091
[Presentation] Acute gut inflammation orchestrates early hematopoiesis via innate immune signaling2019
- Author(s)
  Hayashi Y, Sheoran S, Morishima T, Nakato G, Fukuda S, Takizawa H.
- Organizer
  17th Stem Cell Research Symposium
- Data Source
  KAKENHI-PROJECT-18K16091
[Presentation] Gut microbiota orchestrates early hematopoiesis upon gut inflammation2019
- Author(s)
  Hayashi Y, Fukuda S, Takizawa H
- Organizer
  The 48th Japanese Society for Immunology 2019/
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16091
[Presentation] Microbial signal instructs early hematopoiesis upon intestinal tissue damage2019
- Author(s)
  Hayashi Y, Sezaki M, Sheoran S, Morishima T, Nakato G, Fukuda S, Takizawa H.
- Organizer
  48th Annual Scientific Meeting of International Society of Experimental Hematology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16091
[Presentation] Acute gut inflammation shifts early hematopoiesis toward myelopoiesis2018
- Author(s)
  Hayashi Y, Hitoshi T
- Organizer
  16th Stem Cell Research Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16091
[Presentation] 腸管炎症は造血幹前駆細胞に対して分化バイアスを引き起こす2018
- Author(s)
  林慶和、瀬崎麻衣子、滝澤仁
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K16091

1. 金子直樹 (80805284)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. 川野真太郎 (00398067)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. 服部多市 (10897185)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 金子一成 (00214453)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 佐藤康晴 (00579831)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 安河内友世 (70507813)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KAWAKUBO Tomoyo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 江藤浩之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 森嶋達也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 滝澤仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HAYASHI YOSHIKAZU 林 慶和

Hayashi Yoshikazu 林 慶和

Research Projects

Research Products

Co-Researchers

胎内栄養環境が規定する成熟後の肥満・異所性脂肪蓄積の素因形成メカニズム

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

疾患特異的環境下における自己抗体産生B 細胞とその抗原の同定

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

がん進展におけるACOD1およびイタコン酸の機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The mechanisms of class switching in IgG4-related disease, Kimura's disease and COVID-19

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Expansion of CD4+ cytotoxic T lymphocytes and IgD-CD27- double negative B cells in COVID-19 and autoimmune diseases including IgG4-related disease

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Understanding the cross-organ communication on hematopoiesis regulated via gut microbiota signalingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Understanding the impact of gut inflammation-induced stress on hematopoiesisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Id4 modulates salivary gland homeostasis and its expression is downregulated in IgG4-related disease via miR-486-5p2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hematopoietic stem and progenitor cells integrate microbial signals to promote post‐inflammation gut tissue repair2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] iPSC-Derived Platelets Depleted of HLA Class I Are Inert to Anti-HLA Class I and Natural Killer Cell Immunity.2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Immuno-Modulation of Hematopoietic Stem and Progenitor Cells in Inflammation2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Innate immune signal-mediated regulation and alterations in hematopoiesis2020

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Development of the Hematopoietic System: Role of Inflammatory Factors2019

Author(s)

Journal Title

DOI

HAYASHI YOSHIKAZU 林慶和

Hayashi Yoshikazu 林慶和