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HAYASHI YOSHIKAZU  林 慶和

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Hayashi Yoshikazu  林 慶和

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Researcher Number 00801078
Other IDs
Affiliation (Current) 2025: 福岡歯科大学, 口腔歯学部, 講師
Affiliation (based on the past Project Information) *help 2023 – 2024: 福岡歯科大学, 口腔歯学部, 講師
2020 – 2022: 福岡歯科大学, 口腔歯学部, 助教
2019: 熊本大学, 国際先端医学研究機構, 特任助教
2018: 熊本大学, 国際先端医学研究機構, 特定事業研究員
Review Section/Research Field
Principal Investigator
Basic Section 54010:Hematology and medical oncology-related / Basic Section 57010:Oral biological science-related
Except Principal Investigator
Medium-sized Section 57:Oral science and related fields / Basic Section 57060:Surgical dentistry-related
Keywords
Principal Investigator
造血応答 / 自然免疫 / 腸内細菌 / 腸管炎症 / 多能性前駆細胞 / 造血幹細胞 / ミトコンドリア / がん代謝 / ACOD1 / TCA回路 … More / グルタチオン / 抗酸化 / イタコン酸 / 常在菌 / 炎症性疾患 / 慢性炎症 / 顆粒球 / 骨髄球 / 組織修復 / 造血幹前駆細胞 / 炎症性老化 / 造血幹・前駆細胞 / Gr-1細胞 / Bacteroides / 細胞遊走 / 細胞分化 / TLRシグナル … More
Except Principal Investigator
COVID-19 / IgG4関連疾患 / 免疫複合体 / 自己抗原 / 形質細胞 / 腫瘍 / 自己免疫疾患 / 自己抗体 / 木村氏病 / B細胞 / 濾胞性T細胞 / COVID19 / IgG4 / クラススイッチ / IgG4-related disease / autoimmune disesase / double negative B cell / ダブルネガティブB細胞 / 細胞障害性CD4+ヘルパーT細胞 / DN B細胞 / CD4+CTLs Less
  • Research Projects

    (6 results)
  • Research Products

    (23 results)
  • Co-Researchers

    (9 People)
  •  疾患特異的環境下における自己抗体産生B 細胞とその抗原の同定

    • Principal Investigator
      金子 直樹
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 57:Oral science and related fields
    • Research Institution
      Kyushu University
  •  がん進展におけるACOD1およびイタコン酸の機能解析Principal Investigator

    • Principal Investigator
      林 慶和
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57010:Oral biological science-related
    • Research Institution
      Fukuoka Dental College
  •  The mechanisms of class switching in IgG4-related disease, Kimura's disease and COVID-19

    • Principal Investigator
      金子 直樹
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Kyushu University
  •  Expansion of CD4+ cytotoxic T lymphocytes and IgD-CD27- double negative B cells in COVID-19 and autoimmune diseases including IgG4-related disease

    • Principal Investigator
      金子 直樹
    • Project Period (FY)
      2021 – 2026
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
    • Review Section
      Medium-sized Section 57:Oral science and related fields
    • Research Institution
      Kyushu University
  •  Understanding the cross-organ communication on hematopoiesis regulated via gut microbiota signalingPrincipal Investigator

    • Principal Investigator
      Hayashi Yoshikazu
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      Fukuoka Dental College
  •  Understanding the impact of gut inflammation-induced stress on hematopoiesisPrincipal Investigator

    • Principal Investigator
      Hayashi Yoshikazu
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      Kumamoto University

All 2024 2023 2022 2021 2020 2019 2018

All Journal Article Presentation

  • [Journal Article] Id4 modulates salivary gland homeostasis and its expression is downregulated in IgG4-related disease via miR-486-5p2023

    • Author(s)
      1.Hayashi Y, Kimura S, Yano E, Yoshimoto S, Saeki A, Yasukochi A, Hatakeyama Y, Moriyama M, Nakamura S, Jimi E, Kawakubo-Yasukochi T.
    • Journal Title

      Biochim Biophys Acta Mol Cell Res

      Volume: 1870(2) Issue: 2 Pages: 119404-119404

    • DOI

      10.1016/j.bbamcr.2022.119404

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K09914, KAKENHI-PROJECT-22K10173, KAKENHI-PROJECT-22K19631, KAKENHI-PROJECT-22K17003, KAKENHI-PROJECT-20K17381, KAKENHI-PROJECT-22K18401, KAKENHI-PROJECT-19K22723, KAKENHI-PROJECT-23KK0164, KAKENHI-PROJECT-21K10075
  • [Journal Article] Hematopoietic stem and progenitor cells integrate microbial signals to promote post‐inflammation gut tissue repair2022

    • Author(s)
      Sezaki Maiko、Hayashi Yoshikazu、Nakato Gaku、Wang Yuxin、Nakata Sayuri、Biswas Subinoy、Morishima Tatsuya、Fakruddin Md、Moon Jieun、Ahn Soyeon、Kim Pilhan、Miyamoto Yuji、Baba Hideo、Fukuda Shinji、Takizawa Hitoshi
    • Journal Title

      The EMBO Journal

      Volume: 41 Issue: 22

    • DOI

      10.15252/embj.2022110712

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K08397, KAKENHI-PROJECT-20K17381
  • [Journal Article] iPSC-Derived Platelets Depleted of HLA Class I Are Inert to Anti-HLA Class I and Natural Killer Cell Immunity.2020

    • Author(s)
      Suzuki D, Flahou C, Yoshikawa N, Stirblyte I, Hayashi Y, Sawaguchi A, Akasaka M, Nakamura S, Higashi N, Xu H, Matsumoto T, Fujio K, Manz MG, Hotta A, Takizawa H, Eto K, Sugimoto N.
    • Journal Title

      Stem Cell Reports.

      Volume: 14 Issue: 1 Pages: 49-59

    • DOI

      10.1016/j.stemcr.2019.11.011

    • NAID

      120006777032

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K22675, KAKENHI-PROJECT-18H04164, KAKENHI-PROJECT-18K16091
  • [Journal Article] Immuno-Modulation of Hematopoietic Stem and Progenitor Cells in Inflammation2020

    • Author(s)
      Sezaki Maiko、Hayashi Yoshikazu、Wang Yuxin、Johansson Alban、Umemoto Terumasa、Takizawa Hitoshi
    • Journal Title

      Frontiers in Immunology

      Volume: 11 Pages: 585367-585367

    • DOI

      10.3389/fimmu.2020.585367

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K17381, KAKENHI-PROJECT-18J20690
  • [Journal Article] Innate immune signal-mediated regulation and alterations in hematopoiesis2020

    • Author(s)
      林 慶和、滝澤 仁
    • Journal Title

      Rinsho Ketsueki

      Volume: 61 Issue: 6 Pages: 651-656

    • DOI

      10.11406/rinketsu.61.651

    • NAID

      130007869131

    • ISSN
      0485-1439, 1882-0824
    • Language
      Japanese
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K17381
  • [Journal Article] Development of the Hematopoietic System: Role of Inflammatory Factors2019

    • Author(s)
      Hayashi Y#, Sezaki M#, Takizawa H*
    • Journal Title

      Wiley Interdiscip Rev Dev Biol

      Volume: 27 Issue: 4

    • DOI

      10.1002/wdev.341

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-17H05651, KAKENHI-PROJECT-18H02843, KAKENHI-PROJECT-18J20690, KAKENHI-PROJECT-18K16091
  • [Journal Article] Inflammation and early hematopoiesis2018

    • Author(s)
      滝澤 仁、林 慶和
    • Journal Title

      Rinsho Ketsueki

      Volume: 59 Issue: 10 Pages: 1955-1961

    • DOI

      10.11406/rinketsu.59.1955

    • NAID

      130007496839

    • ISSN
      0485-1439, 1882-0824
    • Language
      Japanese
    • Data Source
      KAKENHI-PROJECT-18K16091
  • [Presentation] イタコン酸によるがん細胞抗酸化システムの破綻2024

    • Author(s)
      林 慶和、佐伯 彩華、吉本 尚平3、畠山 雄次、平田 雅人、自見 英治郎、安河内(川久保) 友世
    • Organizer
      第129回日本解剖学会全国学術集会
    • Data Source
      KAKENHI-PROJECT-23K09133
  • [Presentation] The function of membrane-permeable itaconate in cancer cell growth2024

    • Author(s)
      Ayaka Saeki, Yoshikazu Hayashi, Shohei Yoshimoto, Yuji Hatakeyama, Masato Hirata, Eijiro Jimi, Tomoyo Kawakubo-Yasukochi
    • Organizer
      Kyudai Oral Bioscience & OBT Research Center・DDR Research Center 7th Joint International Symposium 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K09133
  • [Presentation] イタコン酸によるグルタチオン代謝異常に起因したがん細胞増殖抑制機構2023

    • Author(s)
      林 慶和
    • Organizer
      OMシンポジウム2023
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K09133
  • [Presentation] がん細胞増殖におけるイタコン酸の役割2023

    • Author(s)
      佐伯 彩華、林 慶和、吉本 尚平、畠山 雄次、平田 雅人、自見 英治郎、安河内(川久保) 友世
    • Organizer
      第96回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-23K09133
  • [Presentation] イタコン酸によるがん細胞抗酸化システムの制御2023

    • Author(s)
      佐伯 彩華、林 慶和、吉本 尚平、畠山 雄次、平田 雅人、自見 英治郎、安河内(川久保) 友世
    • Organizer
      第65回歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-23K09133
  • [Presentation] Hematopoietic stem and progenitor cells integrate microbial signals to enhance gut tissue repair2021

    • Author(s)
      Maiko Sezaki, Yoshikazu Hayashi, Gaku Nakato, Subinoy Biswas, Tatsuya Morishima, Jieun Moon, Soyeon Ahn, Pilhan Kim, Yuji Miyamoto, Hideo Baba, Shinji Fukuda and Hitoshi Takizawa
    • Organizer
      18th Stem Cell Research Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K17381
  • [Presentation] 慢性炎症は造血幹細胞の骨髄再構築能を低下させる2020

    • Author(s)
      林 慶和
    • Organizer
      第62回歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-20K17381
  • [Presentation] タイトル:成人造血形成における造血幹細胞移行と骨髄リモデリングの時空間的供応2019

    • Author(s)
      Sezaki M, Sham KYC, Hayashi Y, Haeno H, Yokomizo T, Nombela-Arrieta C, Laurenti E, Takizawa H
    • Organizer
      第81回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K16091
  • [Presentation] Microbial signal regulates crosstalk between bone marrow and other organs in early hematopoiesis2019

    • Author(s)
      Hayashi Y
    • Organizer
      The 3rd KU - KAIST Joint Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K16091
  • [Presentation] Early hematopoiesis translates microbial signals to intestinal tissue repair2019

    • Author(s)
      Hayashi Y, Takizawa H, Sezaki M, Sheoran S, Morishima T, Nakato G, Biswas S, Fukuda S.
    • Organizer
      24th Congress of the European Hematology Association
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K16091
  • [Presentation] 自然免疫シグナルは腸管炎症下における造血応答を制御する2019

    • Author(s)
      Hayashi Y, Sezaki M, Nakato G, Sheoran S, Morishima T, Fukuda S, Takizawa H.
    • Organizer
      第81回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K16091
  • [Presentation] Acute gut inflammation orchestrates early hematopoiesis via innate immune signaling2019

    • Author(s)
      Hayashi Y, Sheoran S, Morishima T, Nakato G, Fukuda S, Takizawa H.
    • Organizer
      17th Stem Cell Research Symposium
    • Data Source
      KAKENHI-PROJECT-18K16091
  • [Presentation] Gut microbiota orchestrates early hematopoiesis upon gut inflammation2019

    • Author(s)
      Hayashi Y, Fukuda S, Takizawa H
    • Organizer
      The 48th Japanese Society for Immunology 2019/
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K16091
  • [Presentation] Microbial signal instructs early hematopoiesis upon intestinal tissue damage2019

    • Author(s)
      Hayashi Y, Sezaki M, Sheoran S, Morishima T, Nakato G, Fukuda S, Takizawa H.
    • Organizer
      48th Annual Scientific Meeting of International Society of Experimental Hematology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K16091
  • [Presentation] Acute gut inflammation shifts early hematopoiesis toward myelopoiesis2018

    • Author(s)
      Hayashi Y, Hitoshi T
    • Organizer
      16th Stem Cell Research Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K16091
  • [Presentation] 腸管炎症は造血幹前駆細胞に対して分化バイアスを引き起こす2018

    • Author(s)
      林慶和、瀬崎麻衣子、滝澤仁
    • Organizer
      第80回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K16091
  • 1.  金子 直樹 (80805284)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 2.  川野 真太郎 (00398067)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  服部 多市 (10897185)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  金子 一成 (00214453)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  佐藤 康晴 (00579831)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  KAWAKUBO Tomoyo
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 7.  江藤 浩之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 8.  森嶋 達也
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  滝澤 仁
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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