Kudo Ken-ichi 工藤健一

Researcher Number	00805799
Other IDs	https://orcid.org/0000-0003-1088-9213
Affiliation (Current)	2025: 福島県立医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2020 – 2023: 福島県立医科大学, 医学部, 助教 2019: 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所放射線影響研究部, 博士研究員(任常)
Review Section/Research Field	Principal Investigator Basic Section 63020:Radiation influence-related Except Principal Investigator Basic Section 52040:Radiological sciences-related
Keywords	Principal Investigator 放射線抵抗性 / 放射線応答 / p63 / ΔNp63α / 放射線 / 幹細胞 / オルガノイド / ヒト人工多能性幹細胞 / DNA損傷応答 / 放射線誘発がん … More / 放射線発がん / 再生医療 / γH2AX / DNA損傷 / TP63 / 放射線影響 / ヒト / ラット / 乳腺 … More Except Principal Investigator CRISPR/Cas9 / 責任遺伝子 / 放射線感受性 / 電離放射線 / CRISPR-Cas9 / 染色体転座 Less

乳腺オルガノイドをモデルとした放射線応答/発がんにおけるΔNp63αの核心的役割Principal Investigator
- Principal Investigator
  
  工藤健一
- Project Period (FY)
  2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 63020:Radiation influence-related
- Research Institution
  Fukushima Medical University
標的ゲノム編集/系統的ノックダウンによる染色体転座頻度を増加させる因子の探索
- Principal Investigator
  
  津山尚宏
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Hiroshima University
  Fukushima Medical University
Application of mammary organoids in the investigation of radiation effects on humans and laboratory animalsPrincipal Investigator
- Principal Investigator
  
  Kudo Ken-ichi
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 63020:Radiation influence-related
- Research Institution
  Fukushima Medical University
  National Institutes for Quantum and Radiological Science and Technology

All 2023 2022 2021 2020 2019

All Journal Article Presentation Patent

[Journal Article] Influence of matrix effects by inorganic ions in single-cell direct mass spectrometry2023
- Author(s)
  Kato Y, Kudoh S, Sugiyama E, Sakane I, Tsuyama N, Toyo’oka T, Todoroki K, Hajime Mizuno
- Journal Title
  
  Medical Mass Spectrometry
  
  Volume: 7 Issue: 1 Pages: 43-52
- DOI
  10.24508/mms.2023.06.003
- ISSN
  2432-7441, 2432-745X
- Year and Date
  2023-06-25
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07681, KAKENHI-PROJECT-22K06551, KAKENHI-PROJECT-18K11647
[Journal Article] ΔNp63α transcriptionally represses p53 target genes involved in the radiation-induced DNA damage response2022
- Author(s)
  Kudo Ken-ichi、Tsuyama Naohiro、Nagata Kento、Imaoka Tatsuhiko、Iizuka Daisuke、Sugai-Takahashi Misaki、Muramatsu Moe、Sakai Akira
- Journal Title
  
  Radiation Oncology
  
  Volume: 17 Issue: 1 Pages: 183-183
- DOI
  10.1186/s13014-022-02139-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K20455, KAKENHI-PROJECT-22K18031
[Journal Article] Chromosomal translocation t(11;14) and p53 deletion induced by the CRISPR/Cas9 system in normal B cell-derived iPS cells2021
- Author(s)
  Yusuke Azami, Naohiro Tsuyama, Yu Abe, Misaki Sugai-Takahashi, Ken-Ichi Kudo, Akinobu Ota, Karnan Sivasundaram , Moe Muramatsu, Tomonari Shigemura, Megumi Sasatani, Yuko Hashimoto, Shigehira Saji, Kenji Kamiya, Ichiro Hanamura, Takayuki Ikezoe, Masafumi Onodera, Akira Sakai.
- Journal Title
  
  Sci Rep
  
  Volume: 11 Issue: 1 Pages: 5216-5216
- DOI
  10.1038/s41598-021-84628-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08738, KAKENHI-PROJECT-20K20310, KAKENHI-PROJECT-20K21846, KAKENHI-PROJECT-19K17275, KAKENHI-PROJECT-17H00785, KAKENHI-PROJECT-18H02844, KAKENHI-PROJECT-18K08342, KAKENHI-PROJECT-18K11647, KAKENHI-PROJECT-21K07681, KAKENHI-PROJECT-21K08426, KAKENHI-PROJECT-19K09292
[Journal Article] Flow Cytometry Definition of Rat Mammary Epithelial Cell Populations and Their Distinct Radiation Responses2020
- Author(s)
  Kudo Ken-Ichi、Takabatake Masaru、Nagata Kento、Nishimura Yukiko、Daino Kazuhiro、Iizuka Daisuke、Nishimura Mayumi、Suzuki Keiji、Kakinuma Shizuko、Imaoka Tatsuhiko
- Journal Title
  
  Radiation Research
  
  Volume: 194 Issue: 1 Pages: 22-22
- DOI
  10.1667/rr15566.1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K20455
[Journal Article] 乳腺オルガノイドでヒトと実験動物の放射線影響研究をつなぐ2019
- Author(s)
  工藤健一、今岡達彦
- Journal Title
  
  Medical Science Digest 45号
  
  Volume: 10 Pages: 30-31
- Data Source
  KAKENHI-PROJECT-19K20455
[Patent] がん治療のための放射線増感剤2022
- Inventor(s)
  工藤健一
- Industrial Property Rights Holder
  福島県立医科大学
- Industrial Property Rights Type
  特許
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-19K20455
[Patent] がん治療のための放射線増感剤2022
- Inventor(s)
  工藤健一
- Industrial Property Rights Holder
  福島県立医科大学
- Industrial Property Rights Type
  特許
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-22K18031
[Presentation] ΔNp63α transcriptionally represses p53-target genes in radiation-induced DNA damage response2022
- Author(s)
  Ken-ichi Kudo, Naohiro Tsuyama, Kento Nagata, Tatsuhiko Imaoka, Miwa Fukami, Misaki Sugai-Takahashi, Yusuke Azami, Moe Muramatsu, Akira Sakai
- Organizer
  The 6th International Symposium of the Network-type Joint Usage/Research Center for Radiation Disaster Medical Science
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K20455
[Presentation] ΔNp63α TRANSCRIPTIONALLY REPRESSES P53-TARGET GENES IN RADIATION-INDUCED DNA DAMAGE RESPONSE.2022
- Author(s)
  Ken-ichi Kudo, Naohiro Tsuyama, Kento Nagata, Tatsuhiko Imaoka, Miwa Fukami, Misaki Sugai-Takahashi, Yusuke Azami, Moe Muramatsu, Akira Sakai
- Organizer
  2022 ISSCR Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K20455
[Presentation] ΔNp63α TRANSCRIPTIONALLY REPRESSES P53-TARGET GENES IN RADIATION-INDUCED DNA DAMAGE RESPONSE.2022
- Author(s)
  Ken-ichi Kudo, Naohiro Tsuyama, Kento Nagata, Tatsuhiko Imaoka, Miwa Fukami, Misaki Sugai-Takahashi, Yusuke Azami, Moe Muramatsu, Akira Sakai
- Organizer
  2022 ISSCR Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K18031
[Presentation] ヒト乳腺オルガノイドを用いた放射線応答におけるΔNp63αの影響解析2022
- Author(s)
  工藤健一, 津山尚宏, 今岡達彦, 飯塚大輔, 永田健斗, 坂井晃
- Organizer
  日本放射線影響学会第65回大会
- Invited
- Data Source
  KAKENHI-PROJECT-22K18031
[Presentation] ヒト乳腺オルガノイドを用いた放射線応答におけるΔNp63αの影響解析2022
- Author(s)
  工藤健一, 津山尚宏, 今岡達彦, 飯塚大輔, 永田健斗, 坂井晃
- Organizer
  日本放射線影響学会第65回大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K20455
[Presentation] Analysis of differential gene expression in t(11;14) carrying iPS cells induced by genome editing2022
- Author(s)
  Naohiro Tsuyama, Kenichi Kudo, Misaki Sugai Takahashi, Yusuke Azami, Kenji Kamiya, Akira Sakai.
- Organizer
  第65回日本放射線影響学会
- Data Source
  KAKENHI-PROJECT-21K07681
[Presentation] Study for exploring myeloma-initiating cell using normal B cell-derived iPS cells.2021
- Author(s)
  Yusuke Azami, Naohiro Tsuyama, Yu Abe, Misaki Sugai-Takahashi, Ken-ichi Kudo, Miwa Fukami, Akinobu Ota, Karnan Sivasundaram, Moe Muramatsu, Tomonari Shigemura, Megumi Sasatani, Yuko Hashimoto, Shigehira Saji, Kenji Kamiya, Ichiro Hanamura, Takayuki Ikezoe, Masafumi Onodera, Akira Sakai
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07681
[Presentation] Optimization of chromosome specimen preparation for biodosimetry using chromosome aberration frequency.2021
- Author(s)
  Naohiro Tsuyama, Yu Abe, Misaki Sugai-Takahashi, Kenichi Kudo, Yusuke Azami, Miwa Fukami, Tomisato Miura, Kenji Kamiya, Akira Sakai
- Organizer
  第64回日本放射線影響学会
- Data Source
  KAKENHI-PROJECT-21K07681
[Presentation] 放射線誘発DNA傷害応答へのp53ファミリーΔNp63αの影響2021
- Author(s)
  Ken-ichi Kudo, Naohiro Tsuyama, Kento Nagata, Tatsuhiko Imaoka, Miwa Fukami, Misaki Sugai-Takahashi, Yusuke Azami, Moe Muramatsu, Akira Sakai
- Organizer
  第64回日本放射線影響学会
- Data Source
  KAKENHI-PROJECT-19K20455
[Presentation] Distinct difference of radiation response between luminal and basal cells in rat mammary glands2020
- Author(s)
  Ken-ichi Kudo, Masaru Takabatake, Kento Nagata, Yukiko Nishimura, Kazuhiro Daino, Daisuke Iizuka, Mayumi Nishimura, Keiji Suzuki, Shizuko Kakinuma, Tatsuhiko Imaoka
- Organizer
  The 63nd Japanese Radiation Research Society
- Data Source
  KAKENHI-PROJECT-19K20455
[Presentation] DISTINCT DIFFERENCE OF RADIATION RESPONSE BETWEEN LUMINAL AND BASAL CELLS IN RAT MAMMARY GLANDS2020
- Author(s)
  Ken-ichi Kudo, Masaru Takabatake, Kento Nagata, Yukiko Nishimura, Kazuhiro Daino, Mayumi Nishimura, Daisuke Iizuka, Keiji Suzuki, Shizuko Kakinuma, Tatsuhiko Imaoka
- Organizer
  2020 ISSCR Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K20455
[Presentation] Distinct difference of radiation response between luminal and basal cells in rat mammary glands2020
- Author(s)
  Ken-ichi Kudo, Masaru Takabatake, Kento Nagata, Yukiko Nishimura, Kazuhiro Daino, Daisuke Iizuka, Mayumi Nishimura, Keiji Suzuki, Shizuko Kakinuma, Tatsuhiko Imaoka
- Organizer
  International Society for Stem Cell Research 2020 VIRTUAL
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K20455
[Presentation] Distinct difference of radiation response between luminal and basal cells in rat mammary glands2020
- Author(s)
  Ken-ichi Kudo, Masaru Takabatake, Kento Nagata, Yukiko Nishimura, Kazuhiro Daino, Daisuke Iizuka, Mayumi Nishimura, Keiji Suzuki, Shizuko Kakinuma, Tatsuhiko Imaoka
- Organizer
  The 19th Congress of the Japanese Society for Regeneration Medicine
- Data Source
  KAKENHI-PROJECT-19K20455
[Presentation] 放射線誘発ラット乳腺発がんモデルにおける正常上皮細胞集団間のバランス2020
- Author(s)
  今岡達彦, 工藤健一, 鈴木啓司, 西村まゆみ, 臺野和広, 柿沼志津子
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K20455
[Presentation] Distinct difference of radiation response between luminal and basal cells in rat mammary glands2020
- Author(s)
  Ken-ichi Kudo, Masaru Takabatake, Kento Nagata, Yukiko Nishimura, Kazuhiro Daino, Mayumi Nishimura, Daisuke Iizuka, Keiji Suzuki, Shizuko Kakinuma, Tatsuhiko Imaoka
- Organizer
  第19回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-19K20455
[Presentation] Distinct difference of radiation response between luminal and basal cells in rat mammary glands2020
- Author(s)
  Ken-ichi Kudo, Masaru Takabatake, Kento Nagata, Yukiko Nishimura, Kazuhiro Daino, Mayumi Nishimura, Daisuke Iizuka, Keiji Suzuki, Shizuko Kakinuma, Tatsuhiko Imaoka
- Organizer
  The 63rd JRRS Annual Meeting
- Data Source
  KAKENHI-PROJECT-19K20455
[Presentation] Radiation response of mammary stem and progenitor cells of Sprague-Dawley rats as a potential target of radiation-induced carcinogenesis2019
- Author(s)
  Ken-ichi Kudo, Masaru Takabatake, Yukiko Nishimura, Kazuhiro Daino, Ayaka Hosoki, Mayumi Nishimura, Shizuko Kakinuma, Tatsuhiko Imaoka
- Organizer
  The 17th Stem Cell Research Symposium Information
- Data Source
  KAKENHI-PROJECT-19K20455
[Presentation] Radiation response of mammary stem and progenitor cells in the radiation carcinogenesis model of female Sprague-Dawley rats2019
- Author(s)
  Ken-ichi Kudo, Masaru Takabatake, Yukiko Nishimura, Kazuhiro Daino, Daisuke Iizuka, Mayumi Nishimura, Keiji Suzuki, Shizuko Kakinuma, Tatsuhiko Imaoka
- Organizer
  The 62nd Japanese Radiation Research Society
- Data Source
  KAKENHI-PROJECT-19K20455
[Presentation] Radiation response of mammary stem and progenitor cells in the radiation carcinogenesis model of female Sprague-Dawley rats2019
- Author(s)
  Ken-ichi Kudo, Masaru Takabatake, Yukiko Nishimura, Kazuhiro Daino, Daisuke Iizuka, Mayumi Nishimura, Keiji Suzuki, Shizuko Kakinuma, Tatsuhiko Imaoka
- Organizer
  The 16th International Congress of Radiation Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K20455

1. 津山尚宏 (10335747)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
2. 阿部悠 (00722472)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
3. 坂井晃 (70284221)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results

Kudo Ken-ichi 工藤 健一

Research Projects

Research Products

Co-Researchers

乳腺オルガノイドをモデルとした放射線応答/発がんにおけるΔNp63αの核心的役割Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

標的ゲノム編集/系統的ノックダウンによる染色体転座頻度を増加させる因子の探索

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Application of mammary organoids in the investigation of radiation effects on humans and laboratory animalsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Influence of matrix effects by inorganic ions in single-cell direct mass spectrometry2023

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] ΔNp63α transcriptionally represses p53 target genes involved in the radiation-induced DNA damage response2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Chromosomal translocation t(11;14) and p53 deletion induced by the CRISPR/Cas9 system in normal B cell-derived iPS cells2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Flow Cytometry Definition of Rat Mammary Epithelial Cell Populations and Their Distinct Radiation Responses2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 乳腺オルガノイドでヒトと実験動物の放射線影響研究をつなぐ2019

Author(s)

Journal Title

Data Source

[Patent] がん治療のための放射線増感剤2022

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Data Source

[Patent] がん治療のための放射線増感剤2022

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Data Source

[Presentation] ΔNp63α transcriptionally represses p53-target genes in radiation-induced DNA damage response2022

Author(s)

Organizer

Data Source

[Presentation] ΔNp63α TRANSCRIPTIONALLY REPRESSES P53-TARGET GENES IN RADIATION-INDUCED DNA DAMAGE RESPONSE.2022

Author(s)

Organizer

Data Source

[Presentation] ΔNp63α TRANSCRIPTIONALLY REPRESSES P53-TARGET GENES IN RADIATION-INDUCED DNA DAMAGE RESPONSE.2022

Author(s)

Organizer

Data Source

[Presentation] ヒト乳腺オルガノイドを用いた放射線応答におけるΔNp63αの影響解析2022

Author(s)

Organizer

Data Source

[Presentation] ヒト乳腺オルガノイドを用いた放射線応答におけるΔNp63αの影響解析2022

Author(s)

Organizer

Kudo Ken-ichi 工藤健一