Kon Tomoya 今智矢

… Alternative Names

今智矢コントモヤ

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Researcher Number	00809709
Other IDs	https://orcid.org/0000-0001-6072-3954
Affiliation (Current)	2025: 弘前大学, 医学部附属病院, 助教
Affiliation (based on the past Project Information) *help	2025: 弘前大学, 医学研究科, 客員研究員 2024: 弘前大学, 医学研究科, 助教 2018 – 2021: 弘前大学, 医学研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 52020:Neurology-related Except Principal Investigator Basic Section 46020:Anatomy and histopathology of nervous system-related
Keywords	Principal Investigator αシヌクレイン / レビー小体 / 電子伝達系 / ピルビン酸脱水素酵素 / ミトコンドリア / シヌクレイン / パーキンソン病 Except Principal Investigator 多系統萎縮症 / パーキンソン病 / レビー小体病 … More / モデル動物 / シヌクレイノパチー / オートファジー / シヌクレイン Less

多系統萎縮症におけるαシヌクレイン異常化トリガー分子の解明Principal Investigator
- Principal Investigator
  
  今智矢
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Hirosaki University
パーキンソン病のエネルギー産生経路上流の異常メカニズム解明と新規治療戦略の開発Principal Investigator
- Principal Investigator
  
  今智矢
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Hirosaki University
Activation of autophagy: Implication in the therapeutic approach for alpha-synucleinopathies
- Principal Investigator
  
  Wakabayashi Koichi
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 46020:Anatomy and histopathology of nervous system-related
- Research Institution
  Hirosaki University

All 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] Accumulation of Nonfibrillar TDP-43 in the Rough Endoplasmic Reticulum Is the Early-Stage Pathology in Amyotrophic Lateral Sclerosis.2022
- Author(s)
  Tomoya Kon , Fumiaki Mori , Kunikazu Tanji , Yasuo Miki , Haruo Nishijima , Takashi Nakamura , Iku Kinoshita , Chieko Suzuki , Hidekachi Kurotaki , Masahiko Tomiyama , Koichi Wakabayashi
- Journal Title
  
  Journal of neuropathology and experimental neurology
  
  Volume: 81 Issue: 4 Pages: 271-281
- DOI
  10.1093/jnen/nlac015
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K16592, KAKENHI-PROJECT-18H02533, KAKENHI-PROJECT-20K06887
[Journal Article] Cabergoline, a long-acting dopamine agonist, attenuates L-dopa-induced dyskinesia without L-dopa sparing in a rat model of Parkinson’s disease2022
- Author(s)
  Nishijima Haruo、Mori Fumiaki、Kimura Tamaki、Miki Yasuo、Kinoshita Iku、Nakamura Takashi、Kon Tomoya、Suzuki Chieko、Wakabayashi Koichi、Tomiyama Masahiko
- Journal Title
  
  Neuroscience Research
  
  Volume: - Pages: 93-97
- DOI
  10.1016/j.neures.2022.02.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02533, KAKENHI-PROJECT-20K16570
[Journal Article] Role of VAPB and vesicular profiles in α‐synuclein aggregates in multiple system atrophy2021
- Author(s)
  Mori Fumiaki、Miki Yasuo、Tanji Kunikazu、Kon Tomoya、Tomiyama Masahiko、Kakita Akiyoshi、Wakabayashi Koichi
- Journal Title
  
  Brain Pathology
  
  Volume: 31 Issue: 6
- DOI
  10.1111/bpa.13001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02533, KAKENHI-PROJECT-20K06887
[Journal Article] Effects of Aging on Levo-Dihydroxyphenylalanine- Induced Dyskinesia in a Rat Model of Parkinson’s Disease2021
- Author(s)
  Nishijima Haruo、Kimura Tamaki、Mori Fumiaki、Wakabayashi Koichi、Kinoshita Iku、Nakamura Takashi、Kon Tomoya、Suzuki Chieko、Tomiyama Masahiko
- Journal Title
  
  Frontiers in Aging Neuroscience
  
  Volume: 13 Pages: 650350-650350
- DOI
  10.3389/fnagi.2021.650350
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02533
[Journal Article] Cerebral ring hemorrhages and a massive hematoma in a patient with infective endocarditis2020
- Author(s)
  Kon Tomoya、Nagawa Daiki、Nakata Masamichi、Abe Naoki、Haga Toshihiro、Kijima Hiroshi、Tomiyama Masahiko、Wakabayashi Koichi
- Journal Title
  
  Neuropathology
  
  Volume: 40 Issue: 5 Pages: 526-527
- DOI
  10.1111/neup.12701
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17449, KAKENHI-PROJECT-18H02533
[Journal Article] An autopsy case of primary lateral sclerosis with Alzheimer's disease.2020
- Author(s)
  Nakamura T, Kon T, Kawarabayashi T, Wakabayashi K, Ikeda Y, Shoji M.
- Journal Title
  
  J Neurol Sci.
  
  Volume: 412 Pages: 116792-116792
- DOI
  10.1016/j.jns.2020.116792
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07385, KAKENHI-PROJECT-19K07989, KAKENHI-PROJECT-18H02533
[Journal Article] GABA storage and release in the medial globus pallidus in L-DOPA-induced dyskinesia priming2020
- Author(s)
  Nishijima H, Mori F, Arai A, Zhu G, Wakabayashi K, Okada M, Ueno S, Ichinohe N, Suzuki C, Kon T, Tomiyama M
- Journal Title
  
  Neurobiol Dis
  
  Volume: 143 Pages: 104979-104979
- DOI
  10.1016/j.nbd.2020.104979
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H00892, KAKENHI-PROJECT-17H04319, KAKENHI-PROJECT-18H02533, KAKENHI-PROJECT-18K08846
[Journal Article] Phosphorylated NUB1 distinguishes α-synuclein in Lewy bodies from that in glial cytoplasmic inclusions of multiple system atrophy2019
- Author(s)
  Tanji K, Miki Y, Mori F, Kon T, Kakita A, Takahashi H, Wakabayashi K
- Journal Title
  
  Brain Pathology
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02533
[Journal Article] An autopsy case of early-stage amyotrophic lateral sclerosis with TDP-43-immunoreactive neuronal, but not glial, inclusions2019
- Author(s)
  Kon T, Mori F, Oyama Y, Tanji K, Kimura T, Takahashi S, Wakabayashi K
- Journal Title
  
  Neuropathology
  
  Volume: - Issue: 3 Pages: 224-230
- DOI
  10.1111/neup.12554
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02533, KAKENHI-PROJECT-17K07088
[Journal Article] Neuropathology of Lewy body disease: Clinicopathological crosstalk between typical and atypical cases2019
- Author(s)
  Kon Tomoya、Tomiyama Masahiko、Wakabayashi Koichi
- Journal Title
  
  Neuropathology
  
  Volume: 40 Issue: 1 Pages: 30-39
- DOI
  10.1111/neup.12597
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02533
[Journal Article] Atypical globular glial tauopathy with a combination of types I and II pathology2019
- Author(s)
  Kon Tomoya、Mori Fumiaki、Arai Akira、Miki Yasuo、Tanji Kunikazu、Kurotaki Hidekachi、Tomiyama Masahiko、Wakabayashi Koichi
- Journal Title
  
  Neuropathology
  
  Volume: 39 Issue: 2 Pages: 127-134
- DOI
  10.1111/neup.12536
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07088, KAKENHI-PROJECT-18H02533
[Journal Article] Immunoreactivity of myelin‐associated oligodendrocytic basic protein in Lewy bodies2019
- Author(s)
  Kon Tomoya、Tanji Kunikazu、Mori Fumiaki、Kimura Akari、Kakita Akiyoshi、Wakabayashi Koichi
- Journal Title
  
  Neuropathology
  
  Volume: 39 Issue: 4 Pages: 279-285
- DOI
  10.1111/neup.12564
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02533, KAKENHI-PROJECT-17K07088, KAKENHI-PROJECT-17K07089
[Journal Article] Autophagy Is a Common Degradation Pathway for Bunina Bodies and TDP-43 Inclusions in Amyotrophic Lateral Sclerosis2019
- Author(s)
  Mori Fumiaki、Miki Yasuo、Kon Tomoya、Tanji Kunikazu、Wakabayashi Koichi
- Journal Title
  
  Journal of Neuropathology & Experimental Neurology
  
  Volume: 78 Issue: 10 Pages: 910-921
- DOI
  10.1093/jnen/nlz072
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02533, KAKENHI-PROJECT-17K07088
[Journal Article] Phosphorylated TDP-43 aggregates in skeletal and cardiac muscle are a marker of myogenic degeneration in amyotrophic lateral sclerosis and various conditions.2019
- Author(s)
  Mori F, Tada M, Kon T, Miki Y, Tanji K, Kurotaki H, Tomiyama M, Ishihara T, Onodera O, Kakita A, Wakabayashi K.
- Journal Title
  
  Acta Neuropatholgica Communications
  
  Volume: 7 Issue: 1 Pages: 165-165
- DOI
  10.1186/s40478-019-0824-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07972, KAKENHI-PROJECT-18H02533, KAKENHI-PROJECT-17K07088, KAKENHI-PROJECT-17K09751
[Presentation] Vesicular structures are associated with aggregation of α-synuclein in multiple system atrophy2021
- Author(s)
  Mori F, Miki Y, Tanji K, Kon T, Tomiyama M, Kakita A, Wakabayashi K
- Organizer
  第62回日本神経病理学会総会
- Data Source
  KAKENHI-PROJECT-18H02533
[Presentation] L-dopa 誘発ジスキネジアモデルラットにおける淡蒼球内節の病理学的変化の検討2021
- Author(s)
  中村崇志, 西嶌春生, 森文秋, 木下郁, 今智矢, 鈴木千恵子, 冨山誠彦
- Organizer
  第15回パーキンソン病・運動障害疾患コングレス
- Data Source
  KAKENHI-PROJECT-20K16592
[Presentation] ハロペリドール慢性投与ラットにおける薬剤性パーキンソニズムと遅発性ジスキネジア2021
- Author(s)
  西嶌春生, 木下郁, 中村崇志, 今智矢, 鈴木千恵子, 冨山誠彦
- Organizer
  第15回パーキンソン病・運動障害疾患コングレス
- Data Source
  KAKENHI-PROJECT-20K16592
[Presentation] Immunoreactivity of myelin-associated oligodendrocytic basic protein in Lewy bodies2020
- Author(s)
  Kon T, Tanji K, Mori F, Kakita A, Tomiyama M, Wakabayashi K
- Organizer
  第61回日本神経病理学会総会
- Data Source
  KAKENHI-PROJECT-18H02533
[Presentation] Phosphorylated TDP-43 aggregates in skeletal and cardiac muscle of amyotrophic lateral sclerosis and various conditions2020
- Author(s)
  森文秋、他田真理、今智矢、三木康生、丹治邦和、黒滝日出一、冨山雅彦、石原智彦、小野寺理、柿田明美、若林孝一
- Organizer
  第61回日本神経病理学会総会
- Data Source
  KAKENHI-PROJECT-18H02533
[Presentation] Synphilin-1結合タンパク質（NUB1）のリン酸化とレビー小体への局在2019
- Author(s)
  丹治邦和、三木康生、森文秋、今智矢、柿田明美、高橋均、若林孝一
- Organizer
  第60回日本神経病理学会
- Data Source
  KAKENHI-PROJECT-18H02533

1. Wakabayashi Koichi (50240768)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
2. 丹治邦和 (10271800)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
3. 三木康生 (30709142)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
4. 森文秋 (60200383)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
5. 羽賀敏博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 東海林幹夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 一戸紀孝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 柿田明美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 他田真理

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kon Tomoya 今 智矢

今 智矢 コン トモヤ

Research Projects

Research Products

Co-Researchers

多系統萎縮症におけるαシヌクレイン異常化トリガー分子の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

パーキンソン病のエネルギー産生経路上流の異常メカニズム解明と新規治療戦略の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Activation of autophagy: Implication in the therapeutic approach for alpha-synucleinopathies

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Accumulation of Nonfibrillar TDP-43 in the Rough Endoplasmic Reticulum Is the Early-Stage Pathology in Amyotrophic Lateral Sclerosis.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cabergoline, a long-acting dopamine agonist, attenuates L-dopa-induced dyskinesia without L-dopa sparing in a rat model of Parkinson’s disease2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Role of VAPB and vesicular profiles in α‐synuclein aggregates in multiple system atrophy2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of Aging on Levo-Dihydroxyphenylalanine- Induced Dyskinesia in a Rat Model of Parkinson’s Disease2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cerebral ring hemorrhages and a massive hematoma in a patient with infective endocarditis2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] An autopsy case of primary lateral sclerosis with Alzheimer's disease.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] GABA storage and release in the medial globus pallidus in L-DOPA-induced dyskinesia priming2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Phosphorylated NUB1 distinguishes α-synuclein in Lewy bodies from that in glial cytoplasmic inclusions of multiple system atrophy2019

Author(s)

Journal Title

Data Source

[Journal Article] An autopsy case of early-stage amyotrophic lateral sclerosis with TDP-43-immunoreactive neuronal, but not glial, inclusions2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Neuropathology of Lewy body disease: Clinicopathological crosstalk between typical and atypical cases2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Atypical globular glial tauopathy with a combination of types I and II pathology2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Immunoreactivity of myelin‐associated oligodendrocytic basic protein in Lewy bodies2019

Author(s)

Journal Title

Kon Tomoya 今智矢

今智矢コントモヤ

[Presentation] L-dopa 誘発ジスキネジアモデルラットにおける淡蒼球内節の病理学的変化の検討2021