SU Mei-Tzu 蘇美慈

Researcher Number	00812116
Other IDs
Affiliation (based on the past Project Information) *help	2019 – 2022: 東北大学, 加齢医学研究所, 助教
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related
Keywords	Principal Investigator LILRB4 / immune check point / immunotherapy / immune checkpoint / miRNA / tumor metastasis / Immunosuppression / metastasis / immunosuppression / gp49B / MDSC / fibronectin / exosome

Research Projects
(2 results)
Research Products
(11 results)

A novel mechanism of fibronectin/LILRB4 immune checkpoint in the regulation of the tumor microenvironmentPrincipal Investigator
- Principal Investigator
  
  蘇美慈
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Tohoku University
The role of LILRB4 on MDSC-mediated immunosuppression in tumor environmentPrincipal Investigator
- Principal Investigator
  
  SU Mei-Tzu
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Tohoku University

All 2022 2021 2020 2019

All Journal Article Presentation Patent

[Journal Article] LILRB4 promotes tumor metastasis by regulating MDSCs and inhibiting miR-1 family miRNAs2022
- Author(s)
  Su Mei-Tzu、Kumata Sakiko、Endo Shota、Okada Yoshinori、Takai Toshiyuki
- Journal Title
  
  OncoImmunology
  
  Volume: 11 Issue: 1
- DOI
  10.1080/2162402x.2022.2060907
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16705
[Journal Article] Co-localization of Fibronectin Receptors LILRB4/gp49B and Integrin on Dendritic Cell Surface2022
- Author(s)
  Takahashi Naoyuki, Itoi Sho, Su Mei-Tzu, Endo Shota, Takai Toshiyuki
- Journal Title
  
  Tohoku J Expect Med.
  
  Volume: -
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16705
[Journal Article] Blockade of checkpoint ILT3/LILRB4/gp49B binding to fibronectin ameliorates autoimmune disease in BXSB/<i>Yaa</i> mice2021
- Author(s)
  Su Mei-Tzu、Inui Masanori、Wong Yi Li、Takahashi Maika、Sugahara-Tobinai Akiko、Ono Karin、Miyamoto Shotaro、Murakami Keiichi、Itoh-Nakadai Ari、Kezuka Dai、Itoi So、Endo Shota、Hirayasu Kouyuki、Arase Hisashi、Takai Toshiyuki
- Journal Title
  
  International Immunology
  
  Volume: 33 Issue: 8 Pages: 447-458
- DOI
  10.1093/intimm/dxab028
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16705, KAKENHI-PROJECT-17K08874, KAKENHI-PROJECT-18H05279
[Patent] がん患者の予後を予測するためのバイオマーカー、がん患者の予後を予測するための方法、及び、がん患者の予後を予測するためのキット2021
- Inventor(s)
  高井俊行、熊田早希子、岡田克典、SU MEI TZU 他
- Industrial Property Rights Holder
  東北大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-119757
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-19K16705
[Patent] 免疫チェックポイントB4-B4リガンド（フィブロネクチン）阻害剤2020
- Inventor(s)
  高井俊行，乾　匡範，蘇　美慈，遠藤章太
- Industrial Property Rights Holder
  高井俊行，乾　匡範，蘇　美慈，遠藤章太
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-19K16705
[Patent] Do not publish for confidentiality2019
- Inventor(s)
  高井俊行、乾匡範、蘇美慈、遠藤章太
- Industrial Property Rights Holder
  高井俊行、乾匡範、蘇美慈、遠藤章太
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-19K16705
[Presentation] The immune inhibitory receptor LILRB4/gp49B reduces anti-tumor exosomal miRNA levels in plasma through promoting MDSC-mediated immunosuppression2021
- Author(s)
  Sakiko Kumata, Mei-Tzu Su, Shota Endo, Toshiyuki Takai
- Organizer
  第50回日本免疫学会学術集会 (Web)
- Data Source
  KAKENHI-PROJECT-19K16705
[Presentation] Blockade of checkpoint ILT3/LILRB4/gp49B binding to fibronectin ameliorates autoimmune disease in BXSB/Yaa mice2021
- Author(s)
  Mei-Tzu Su, Masanori Inui, Shota Endo, Toshiyuki Takai
- Organizer
  Virtual IMMUNOLOGY 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16705
[Presentation] Blockade of checkpoint ILT3/LILRB4/gp49B binding to fibronectin ameliorates autoimmune disease in BXSB/Yaa mice2021
- Author(s)
  Mei-Tzu Su, Masanori Inui, Shota Endo, Kouyuki Hirayasu, Hisashi Arase, Toshiyuki Takai
- Organizer
  第50回日本免疫学会学術集会 (Web)
- Data Source
  KAKENHI-PROJECT-19K16705
[Presentation] Gp49B-fibronectin interaction negatively regulates osteoclastogenesis2021
- Author(s)
  Dai Kezuka, Karin Ono, Mei-Tzu Su, Toshiyuki Takai
- Organizer
  第50回日本免疫学会学術集会 (Web)
- Data Source
  KAKENHI-PROJECT-19K16705
[Presentation] The immune inhibitory molecule LILRB4 regulates MDSC polarization to promote immunosuppression during tumor progression2021
- Author(s)
  Mei-Tzu SU
- Organizer
  9th Symposium of the Smart-Aging Research Center, Tohoku University
- Invited
- Data Source
  KAKENHI-PROJECT-19K16705

SU Mei-Tzu 蘇 美慈

Research Projects

Research Products

A novel mechanism of fibronectin/LILRB4 immune checkpoint in the regulation of the tumor microenvironmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of LILRB4 on MDSC-mediated immunosuppression in tumor environmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] LILRB4 promotes tumor metastasis by regulating MDSCs and inhibiting miR-1 family miRNAs2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Co-localization of Fibronectin Receptors LILRB4/gp49B and Integrin on Dendritic Cell Surface2022

Author(s)

Journal Title

Data Source

[Journal Article] Blockade of checkpoint ILT3/LILRB4/gp49B binding to fibronectin ameliorates autoimmune disease in BXSB/<i>Yaa</i> mice2021

Author(s)

Journal Title

DOI

Data Source

[Patent] がん患者の予後を予測するためのバイオマーカー、がん患者の予後を予測するための方法、及び、がん患者の予後を予測するためのキット2021

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Industrial Property Number

Filing Date

Data Source

[Patent] 免疫チェックポイントB4-B4リガンド（フィブロネクチン）阻害剤2020

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Data Source

[Patent] Do not publish for confidentiality2019

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Data Source

[Presentation] The immune inhibitory receptor LILRB4/gp49B reduces anti-tumor exosomal miRNA levels in plasma through promoting MDSC-mediated immunosuppression2021

Author(s)

Organizer

Data Source

[Presentation] Blockade of checkpoint ILT3/LILRB4/gp49B binding to fibronectin ameliorates autoimmune disease in BXSB/Yaa mice2021

Author(s)

Organizer

Data Source

[Presentation] Blockade of checkpoint ILT3/LILRB4/gp49B binding to fibronectin ameliorates autoimmune disease in BXSB/Yaa mice2021

Author(s)

Organizer

Data Source

[Presentation] Gp49B-fibronectin interaction negatively regulates osteoclastogenesis2021

Author(s)

Organizer

Data Source

[Presentation] The immune inhibitory molecule LILRB4 regulates MDSC polarization to promote immunosuppression during tumor progression2021

Author(s)

Organizer

Data Source

SU Mei-Tzu 蘇美慈