WATANABE RYUTA 渡辺隆太

Researcher Number	00813635
Other IDs
Affiliation (Current)	2025: 愛媛大学, 医学部附属病院, 特任講師
Affiliation (based on the past Project Information) *help	2021 – 2024: 愛媛大学, 医学部附属病院, 助教 2019 – 2021: 愛媛大学, 医学部附属病院, 医員
Review Section/Research Field	Principal Investigator Basic Section 56030:Urology-related Except Principal Investigator Basic Section 56030:Urology-related / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
Keywords	Principal Investigator 前立腺癌 / 遺伝子解析 / 神経内分泌分化 / IDCP / シングルセル解析 / 空間的遺伝子発現解析 / 神経内分泌前立腺癌 / 分解制御剤 / 蛋白質分解 / 前立腺癌関連SPOP変異 … More / エトポシド / PARP阻害剤 / topoisomerase2 / 遺伝子変異 / CUL3 / 体細胞変異 / ゲノム不安定性 / TMPRSS2-ERG融合遺伝子 / SPOP遺伝子 / TDP1/2 / TOP阻害剤 / TOP2A / DNA修復 / ETV1 / TMPRSS-ERG融合遺伝子 / SPOP … More Except Principal Investigator 前立腺癌 / スフェロイド / 導管内浸潤前立腺癌 / 導管癌 / 神経内分泌癌 / シングルセル解析 / 腎癌 / 質量分析法 / PSMA / 腎がん Less

前立腺癌スフェロイドのシングルセル解析による導管内浸潤前立腺癌の病態解明
- Principal Investigator
  
  三浦徳宣
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Ehime University
腎癌関連血管内皮細胞におけるPSMAの発現制御機構及び、その分子機能の解明
- Principal Investigator
  
  菊川忠彦
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Ehime University
International collaboration research on the identification of novel driver genes for prostate cancer by single cell analysis.
- Principal Investigator
  
  菊川忠彦
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Ehime University
シングルセル解析による腫瘍微小環境を介した前立腺神経内分泌腫瘍発生機序の解明Principal Investigator
- Principal Investigator
  
  渡辺隆太
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Ehime University
Application of the degradation system for ETV1 to prostate cancer therapyPrincipal Investigator
- Principal Investigator
  
  WATANABE RYUTA
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Ehime University

All 2024 2023 2022 2021 2020

All Journal Article Presentation Book

[Book] 『仕掛けなければ，何も生まれない』コネなし臨床医の研究留学挑戦録2023
- Author(s)
  渡辺隆太
- Total Pages
  6
- Publisher
  実験医学
- Data Source
  KAKENHI-PROJECT-22K09449
[Journal Article] 神経内分泌前立腺癌のシングルセル解析と農学分野への応用の可能性2024
- Author(s)
  渡辺隆太、雑賀隆史
- Journal Title
  
  アグリバイオ
  
  Volume: 8 (2) Pages: 173-177
- Data Source
  KAKENHI-PROJECT-22K09449
[Journal Article] Spatial Gene Expression Analysis Reveals Characteristic Gene Expression Patterns of De Novo Neuroendocrine Prostate Cancer Coexisting with Androgen Receptor Pathway Prostate Cancer2023
- Author(s)
  Watanabe Ryuta、Miura Noriyoshi、Kurata Mie、Kitazawa Riko、Kikugawa Tadahiko、Saika Takashi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 10 Pages: 8955-8955
- DOI
  10.3390/ijms24108955
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09449, KAKENHI-PROJECT-21K09373
[Journal Article] シングルセル解析による前立腺癌神経内分泌分化機序解明2023
- Author(s)
  渡辺隆太、雑賀隆史
- Journal Title
  
  細胞
  
  Volume: 55 (7) Pages: 389-391
- Data Source
  KAKENHI-PROJECT-22K09449
[Journal Article] IDCP症例における遺伝子異常の解析2023
- Author(s)
  渡辺隆太、塩出涼、鈴木大一郎、信森祥太、杉原直哉、山川真季、佐伯佳央里、河野玲奈、新井欧介、大西智也、角田俊雄、野田輝乙、西村謙一、福本哲也、三浦徳宣、倉田美恵、宮内勇貴、北澤理子、Michael C Haffner、菊川忠彦、雑賀隆史
- Journal Title
  
  泌尿器外科
  
  Volume: 36(8) Pages: 939-941
- Data Source
  KAKENHI-PROJECT-22K09449
[Journal Article] 神経内分泌前立腺癌の理解を目指したシングルセル解析の応用2023
- Author(s)
  渡辺隆太、雑賀隆史
- Journal Title
  
  38 (14)
  
  Volume: 38 (14) Pages: 1238-1241
- Data Source
  KAKENHI-PROJECT-22K09449
[Journal Article] 愛媛大学における神経内分泌前立腺癌の治療経験と病理学的考察（総説）2022
- Author(s)
  渡辺隆太
- Journal Title
  
  泌尿器外科
  
  Volume: 35 (8) Pages: 894-896
- Data Source
  KAKENHI-PROJECT-22K09449
[Journal Article] SPOP is essential for DNA-protein crosslink repair in prostate cancer cells: SPOP-dependent removal of topoisomerase 2A from the topoisomerase 2A-DNA cleavage complex.2020
- Author(s)
  Watanabe R, Maekawa M, Hieda M, Taguchi T, Miura N, Kikugawa T, Saika T, Higashiyama S.
- Journal Title
  
  Mol Biol Cell
  
  Volume: 31 Issue: 6 Pages: 478-490
- DOI
  10.1091/mbc.e19-08-0456
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06226, KAKENHI-PROJECT-19K18613, KAKENHI-PROJECT-18K09137
[Presentation] A genetic landscape of de novo neuroendocrine prostate cancer and possible novel therapeutic strategies unveiled by spatial gene expression analysis2024
- Author(s)
  Ryuta Watanabe, Noriyoshi Miura, Tadahiko Kikugawa, Takashi Saika
- Organizer
  2024 AUA Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22KK0135
[Presentation] Exploring the Genomic Landscape of de novo Neuroendocrine Prostate Cancer: Insights for Innovative Therapies from Spatial Gene Expression Analysis2024
- Author(s)
  Ryuta Watanabe, Noriyoshi Miura, Tadahiko Kikugawa, Takashi Saika
- Organizer
  the 39th Annual EAU Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22KK0135
[Presentation] 空間的遺伝子発現解析を用いた de novo神経内分泌前立腺癌における遺伝子発現パターンの探索2024
- Author(s)
  渡辺隆太
- Organizer
  泌尿器科分子細胞研究会
- Data Source
  KAKENHI-PROJECT-22K09449
[Presentation] Exploring the Genomic Landscape of de novo Neuroendocrine Prostate Cancer: Insights for Innovative Therapies from Spatial Gene Expression Analysis2024
- Author(s)
  Ryuta Watanabe, Noriyoshi Miura, Tadahiko Kikugawa, Takashi Saika
- Organizer
  AACR Annual Meeting 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22KK0135
[Presentation] Prostate-specific membrane antigen expression in endothelial cells of renal tumor-associated neovasculature and risk of recurrence for renal cell carcinoma2024
- Author(s)
  Tadahiko Kikugawa, Keito Kagimoto, Ryuta Watanabe, Noriyoshi Miura, Takashi Saika
- Organizer
  第111回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-22K09529
[Presentation] 愛媛大学における前立腺癌研究の黎明と展望2024
- Author(s)
  渡辺隆太
- Organizer
  2024年がん関連3学会Rising star ネットワーキング
- Invited
- Data Source
  KAKENHI-PROJECT-22K09449
[Presentation] Prostate-specific membrane antigen expression in endothelial cells of renal tumor-associated neovasculature and risk of recurrence for renal cell carcinoma2024
- Author(s)
  Tadahiko Kikugawa, Keito Kagimoto, Ryuta Watanabe, Noriyoshi Miura, Takashi Saika
- Organizer
  2024 ASCO GENITOURINARY CANCERS SYMPOSIUM
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09529
[Presentation] Detection of intraductal carcinoma of the prostate (IDCP) cases focusing on high-grade prostaticintraepithelial neoplasia (PIN) findings regarding invasive carcinoma of the prostate2023
- Author(s)
  渡辺隆太
- Organizer
  EAU（欧州泌尿器科学会）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09449
[Presentation] Detection of intraductal carcinoma of the prostate (IDCP) cases focusing on high-grade prostatic intraepithelial neoplasia (PIN) findings regarding invasive carcinoma of the prostate.2023
- Author(s)
  渡辺隆太
- Organizer
  EAU23（欧州泌尿器科学会）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09449
[Presentation] Detection of intraductal carcinoma of the prostate (IDCP) cases focusing on high-grade prostaticintraepithelial neoplasia (PIN) findings regarding invasive carcinoma of the prostate2023
- Author(s)
  渡辺隆太
- Organizer
  ASCO-GU（アメリカ臨床腫瘍学会-泌尿器がんシンポジウム）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09449
[Presentation] Prostate-Specific Membrane Antigen Expression in Endothelial Cells of Renal Tumor-Associated Neovasculature and Risk of Recurrence for Renal Cell Carcinoma2023
- Author(s)
  Tadahiko Kikugawa, Keito Kagimoto, Ryuta Watanabe, Noriyoshi Miura, Takashi Saika
- Organizer
  The 43rd Congress of the Societe Internationale d`Urologie
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09529
[Presentation] Detection of intraductal carcinoma of the prostate (IDCP) cases focusing on high-grade prostatic intraepithelial neoplasia (PIN) findings regarding invasive carcinoma of the prostate.2023
- Author(s)
  渡辺隆太
- Organizer
  AACR23 (米国癌学会学会)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09449
[Presentation] Detection of intraductal carcinoma of the prostate (IDCP) cases focusing on high-grade prostatic intraepithelial neoplasia (PIN) findings regarding invasive carcinoma of the prostate.2023
- Author(s)
  渡辺隆太
- Organizer
  ASCO-GU23（米国臨床腫瘍学会泌尿器癌シンポジウム）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09449
[Presentation] Detection of intraductal carcinoma of the prostate (IDCP) cases focusing on high-grade prostaticintraepithelial neoplasia (PIN) findings regarding invasive carcinoma of the prostate2023
- Author(s)
  渡辺隆太
- Organizer
  AACR（米国腫瘍学会）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09449
[Presentation] IDCPを深堀する2023
- Author(s)
  渡辺隆太
- Organizer
  前立腺シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-22K09449
[Presentation] PSMA-positive membranes secreted from prostate cancer cells have potency to transform vascular endothelial cells into an angiogenic state2022
- Author(s)
  Ryuta Watanabe
- Organizer
  AARC 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K18613
[Presentation] IDCP症例における遺伝子異常の解析2022
- Author(s)
  渡辺隆太
- Organizer
  前立腺シンポジウム
- Data Source
  KAKENHI-PROJECT-22K09449
[Presentation] 治療誘因型神経内分泌前立腺癌における ERG発現の検討2022
- Author(s)
  渡辺隆太
- Organizer
  西日本泌尿器科学会
- Data Source
  KAKENHI-PROJECT-22K09449
[Presentation] Effect of PSMA-positive membranes secreted from prostate cancer cells on vascular endothelial cells2022
- Author(s)
  Ryuta Watanabe
- Organizer
  ASCO-GU2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K18613
[Presentation] 浸潤癌を背景とするHigh Grade PIN所見に着目したIDCP症例の検索2022
- Author(s)
  渡辺隆太
- Organizer
  日本泌尿器腫瘍学会
- Data Source
  KAKENHI-PROJECT-22K09449
[Presentation] The novel role of SPOP in regulating topoisomerase 2A in prostate cancer cells as a potential therapeutic marker for DNA repair targeted therapy2021
- Author(s)
  渡辺隆太
- Organizer
  西日本泌尿器科学会
- Data Source
  KAKENHI-PROJECT-19K18613
[Presentation] 愛媛大学における神経内分泌前立腺癌の治療経験と病理学的考察2021
- Author(s)
  渡辺隆太
- Organizer
  前立腺シンポジウム
- Data Source
  KAKENHI-PROJECT-19K18613
[Presentation] 前立腺癌細胞のtopoisomerase2A制御におけるSPOPの新規機能解明とDNA修復標的治療の治療マーカーとしての可能性2021
- Author(s)
  渡辺隆太
- Organizer
  泌尿器分子細胞研究会
- Data Source
  KAKENHI-PROJECT-19K18613
[Presentation] LNCaP cellsから放出されるPSMA陽性vesicleが血管内皮細胞の血管新生能を亢進する2021
- Author(s)
  渡辺隆太
- Organizer
  泌尿器腫瘍学会
- Data Source
  KAKENHI-PROJECT-19K18613
[Presentation] 前立腺癌細胞のtopoisomerase2A制御における SPOPの新規機能解明と DNA修復標的治療の治療マーカーとしての可能性2020
- Author(s)
  渡辺　隆太
- Organizer
  第108回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-19K18613
[Presentation] The novel role of SPOP in regulating topoisomerase 2A in prostate cancer cells as a potential therapeutic marker for DNA repair targeted therapy2020
- Author(s)
  Ryuta Watanabe
- Organizer
  2020 AUA annual meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K18613
[Presentation] 前立腺癌細胞のtopoisomerase2A制御における SPOPの新規機能解明と DNA修復標的治療の治療マーカーとしての可能性2020
- Author(s)
  渡辺　隆太
- Organizer
  第29回泌尿器科分子細胞研究会
- Data Source
  KAKENHI-PROJECT-19K18613

1. 菊川忠彦 (70444734)

# of Collaborated Projects: 4 results

# of Collaborated Products: 8 results
2. 雑賀隆史 (10314676)

# of Collaborated Projects: 4 results

# of Collaborated Products: 11 results
3. 三浦徳宣 (80554427)

# of Collaborated Projects: 4 results

# of Collaborated Products: 8 results
4. 東山繁樹 (60202272)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
5. 飯尾浩之 (80972231)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 角田俊雄 (70988435)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 沢田雄一郎 (80793554)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. HIEDA Miki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

WATANABE RYUTA 渡辺 隆太

Research Projects

Research Products

Co-Researchers

前立腺癌スフェロイドのシングルセル解析による導管内浸潤前立腺癌の病態解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

腎癌関連血管内皮細胞におけるPSMAの発現制御機構及び、その分子機能の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

International collaboration research on the identification of novel driver genes for prostate cancer by single cell analysis.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

シングルセル解析による腫瘍微小環境を介した前立腺神経内分泌腫瘍発生機序の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Application of the degradation system for ETV1 to prostate cancer therapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] 『仕掛けなければ，何も生まれない』 コネなし臨床医の研究留学挑戦録2023

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] 神経内分泌前立腺癌のシングルセル解析と農学分野への応用の可能性2024

Author(s)

Journal Title

Data Source

[Journal Article] Spatial Gene Expression Analysis Reveals Characteristic Gene Expression Patterns of De Novo Neuroendocrine Prostate Cancer Coexisting with Androgen Receptor Pathway Prostate Cancer2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] シングルセル解析による前立腺癌神経内分泌分化機序解明2023

Author(s)

Journal Title

Data Source

[Journal Article] IDCP症例における遺伝子異常の解析2023

Author(s)

Journal Title

Data Source

[Journal Article] 神経内分泌前立腺癌の理解を目指したシングルセル解析の応用2023

Author(s)

Journal Title

Data Source

[Journal Article] 愛媛大学における神経内分泌前立腺癌の治療経験と病理学的考察 （総説）2022

Author(s)

Journal Title

Data Source

[Journal Article] SPOP is essential for DNA-protein crosslink repair in prostate cancer cells: SPOP-dependent removal of topoisomerase 2A from the topoisomerase 2A-DNA cleavage complex.2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] A genetic landscape of de novo neuroendocrine prostate cancer and possible novel therapeutic strategies unveiled by spatial gene expression analysis2024

Author(s)

Organizer

Data Source

[Presentation] Exploring the Genomic Landscape of de novo Neuroendocrine Prostate Cancer: Insights for Innovative Therapies from Spatial Gene Expression Analysis2024

Author(s)

Organizer

Data Source

[Presentation] 空間的遺伝子発現解析を用いた de novo神経内分泌前立腺癌における遺伝子発現パターンの探索2024

Author(s)

Organizer

WATANABE RYUTA 渡辺隆太

[Book] 『仕掛けなければ，何も生まれない』コネなし臨床医の研究留学挑戦録2023

[Journal Article] 愛媛大学における神経内分泌前立腺癌の治療経験と病理学的考察（総説）2022