Kawai Takayuki 河合隆之

Researcher Number	00813867
Affiliation (Current)	2025: 京都大学, 医学研究科, 客員研究員 2025: 公益財団法人田附興風会, 医学研究所腫瘍研究部, 研究員
Affiliation (based on the past Project Information) *help	2021 – 2023: 公益財団法人田附興風会, 医学研究所腫瘍研究部, 研究員 2018 – 2021: 京都大学, 医学研究科, 客員研究員 2017: 京都大学, 医学研究科, 医員
Review Section/Research Field	Principal Investigator Basic Section 55020:Digestive surgery-related Except Principal Investigator Basic Section 55020:Digestive surgery-related / Pediatric surgery / Digestive surgery
Keywords	Principal Investigator 癌幹細胞 / 肝細胞癌 / 肝癌 / 大腸癌肝転移 / 高悪性度肝癌 / 肝臓外科学 Except Principal Investigator 人工臓器 / 人工肝臓 / 再生医療 / 臓器作製 … More / 癌幹細胞 / 胆管癌 / K19陽性肝細胞癌 / ゲノム不均一性 / 肝細胞癌 / ゲノムシークエンス / ゲノム / 肝癌 / ゲノム解析 / 細胆管細胞癌 / 混合型肝癌 / 胆管上皮細胞 / 細胞外基質 / 脱細胞化 / 脱細胞化肝臓 / iPS細胞 / 再生医学 / ヒトiPS細胞 / 肝臓移植 / 組織工学 / 肝移植 / 多能性幹細胞 / 幹細胞生物学 / 胆道外科学 / 上皮間葉転換 / 転移能 Less

肝細胞癌における癌幹細胞を標的とした新規治療戦略構築に関する研究Principal Investigator
- Principal Investigator
  
  河合隆之
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  The Tazuke Kofukai
Genomic heterogeneity in hepatocellular carcinoma from a cancer stem cell perspective.
- Principal Investigator
  
  Ishii Takamichi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kyoto University
Improvement of survival rate and ECM analysis using bio-engineered liver derived 3D scaffold
- Principal Investigator
  
  Fukumitsu Ken
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kyoto University
Identification of the metastatic mechanism of keratin 19 positive cancer stem cells and novel therapeutic targets in hepatocellular carcinomaPrincipal Investigator
- Principal Investigator
  
  Kawai Takayuki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kyoto University
Isolation of cancer stem cells of cholangiocarcinoma and identification of new therapeutic targets of cholangiocarcinoma
- Principal Investigator
  
  Ishii Takamichi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto University
Development of the transplantable artificial liver using iPS cells and decellularized liver
- Principal Investigator
  
  Yasuchika Kentaro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatric surgery
- Research Institution
  Kyoto University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] Integrated analyses of the genetic and clinicopathological features of cholangiolocarcinoma: cholangiolocarcinoma may be characterized by mismatch‐repair deficiency2024
- Author(s)
  Makino Kenta、Ishii Takamichi、Takeda Haruhiko、Saito Yoichi、Fujiwara Yukio、Fujimoto Masakazu、Ito Takashi、Wakama Satoshi、Kumagai Ken、Munekage Fumiaki、Horie Hiroshi、Tomofuji Katsuhiro、Oshima Yu、Uebayashi Elena Yukie、Kawai Takayuki、Ogiso Satoshi、Fukumitsu Ken、Takai Atsushi、Seno Hiroshi、Hatano Etsuro
- Journal Title
  
  The Journal of Pathology
  
  Volume: 263 Issue: 1 Pages: 32-46
- DOI
  10.1002/path.6257
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K16461, KAKENHI-PROJECT-22K08689
[Journal Article] Combined hepatocellular-cholangiocarcinoma compared to hepatocellular carcinoma and intrahepatic cholangiocarcinoma: Different survival, similar recurrence2024
- Author(s)
  Amory B, Goumard C, Laurent A, Langella S, Cherqui D, Salame E, Barbier L, Soubrane O, Farges O, Hobeika C, Kawai T, Regimbeau JM, Faitot F, Pessaux P, Truant S, Resende V, Calderaro J, Augustin J, Caruso S, Sommacale D, Hofmeyr S, Ferrero A, Fuks D, Vibert E, Torzilli G, Scatton O, Brustia R
- Journal Title
  
  Surgery
  
  Volume: 175 Issue: 2 Pages: 413-423
- DOI
  10.1016/j.surg.2023.09.040
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K16461
[Journal Article] Management of Patients Receiving Antiplatelet Therapy During Gastroenterological Surgery2023
- Author(s)
  Fujikawa T, Hasegawa S, Takahashi R, Naito S, Kaihara S, Uryuhara K, Hirata K, Tamura T, Terajima H, Kawai T, Okabe H, Machimoto T, Tanaka H, Honma S, Furumoto K, Honda G, Uemura S, Nishitai R, Hida K, Aoyama R, Wada S, Hirose T, Obama K
- Journal Title
  
  Annals of Surgery
  
  Volume: - Issue: 1 Pages: 82-90
- DOI
  10.1097/sla.0000000000006136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K16461
[Journal Article] Impact of anatomical liver resection on patient survival in KRAS-wild-type colorectal liver metastasis: A multicenter retrospective study2022
- Author(s)
  Kawai Takayuki、Ishii Takamichi、Uchida Yoichiro、Sato Asahi、Naito Shigetoshi、Kitaguchi Kazuhiko、Komatsubara Takashi、Nakamura Ikuo、Ogiso Satoshi、Fukumitsu Ken、Seo Satoru、Fujikawa Takahisa、Yasuchika Kentaro、Hirose Tetsuro、Zaima Masazumi、Taura Kojiro、Hatano Etsuro、Terajima Hiroaki
- Journal Title
  
  Surgery
  
  Volume: 172 Issue: 4 Pages: 1133-1140
- DOI
  10.1016/j.surg.2022.05.014
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08689, KAKENHI-PROJECT-21K16461
[Journal Article] Clinical impact of lymphocyte/C-reactive protein ratio on postoperative outcomes in patients with rectal cancer who underwent curative resection2022
- Author(s)
  Yamamoto Takehito、Fukuda Meiki、Okuchi Yoshihisa、Oshimo Yoshiki、Nishikawa Yuta、Hisano Koji、Kawai Takayuki、Iguchi Kohta、Okuda Yukihiro、Kamimura Ryo、Tanaka Eiji、Terajima Hiroaki
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 17136-17136
- DOI
  10.1038/s41598-022-21650-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K16461, KAKENHI-PROJECT-21K16487
[Journal Article] Laparoscopic versus open liver resection for intrahepatic cholangiocarcinoma: Report of an international multicenter cohort study with propensity score matching2022
- Author(s)
  Brustia R, Laurent A, Goumard C, Langella S, Cherqui D, Kawai T, Soubrane O, Cauchy F, Farges O, Menahem B, Hobeika C, Rhaiem R, Sommacale D, Okumura S, Hofmeyr S, Ferrero A, Pruvot F, Regimbeau JM, Fuks D, Vibert E, Scatton O
- Journal Title
  
  Surgery
  
  Volume: 171 Issue: 5 Pages: 1290-1302
- DOI
  10.1016/j.surg.2021.08.015
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K16461
[Journal Article] Laparoscopic liver resection versus percutaneous radiofrequency ablation for small hepatocellular carcinoma2021
- Author(s)
  Ogiso Satoshi、Seo Satoru、Eso Yuji、Yoh Tomoaki、Kawai Takayuki、Okumura Shinya、Ishii Takamichi、Fukumitsu Ken、Taura Kojiro、Seno Hiroshi、Uemoto Shinji
- Journal Title
  
  HPB
  
  Volume: 23 Issue: 4 Pages: 533-537
- DOI
  10.1016/j.hpb.2020.08.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08701
[Journal Article] Preoperative risk score for prediction of long-term outcomes after hepatectomy for intrahepatic cholangiocarcinoma: Report of a collaborative, international-based, external validation study2020
- Author(s)
  Brustia R, Langella S, Kawai T, Fonseca GM, Schielke A, Colli F, Resende V, Fleres F, Roulin D, Leyman P, Giacomoni A, Granger B, Fartoux L, De Carlis L, Demartines N, Sommacale D, Sanches MD, Patrono D, Detry O, Herman P, Okumura S, Ferrero A, Scatton O, Uemoto S, Perdigao F, et al.
- Journal Title
  
  European Journal of Surgical Oncology
  
  Volume: 46 Issue: 4 Pages: 560-571
- DOI
  10.1016/j.ejso.2019.10.041
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16305
[Journal Article] Laparoscopic right hepatectomy using the caudal approach is superior to open right hepatectomy with anterior approach and liver hanging maneuver: a comparison of short-term outcomes2020
- Author(s)
  Yoh Tomoaki、Cauchy Fransois、Kawai Takayuki、Schneck Anne-Sophie、Le Roy Bertrand、Goumard Claire、Sepulveda Ailton、Dokmak Safi、Farges Olivier、Scatton Olivier、Soubrane Olivier
- Journal Title
  
  Surgical Endoscopy
  
  Volume: 34 Issue: 2 Pages: 636-645
- DOI
  10.1007/s00464-019-06810-1
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16305
[Journal Article] Pure laparoscopic versus open hemihepatectomy: a critical assessment and realistic expectations - a propensity score-based analysis of right and left hemihepatectomies from nine European tertiary referral centers2020
- Author(s)
  Cipriani F, Alzoubi M, Fuks D, Ratti F, Kawai T, Berardi G, Barkhatov L, Lainas P, Van der Poel M, Faoury M, Besselink MG, D'Hondt M, Dagher I, Edwin B, Troisi RI, Scatton O, Gayet B, Aldrighetti L, Abu Hilal M.
- Journal Title
  
  Journal of Hepato-Biliary-Pancreatic Sciences
  
  Volume: 27(1) Issue: 1 Pages: 3-15
- DOI
  10.1002/jhbp.662
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16305
[Journal Article] Impact of cirrhosis in patients undergoing laparoscopic liver resection in a nationwide multicentre survey2020
- Author(s)
  Hobeika C, Fuks D, Cauchy F, Goumard C, Soubrane O, Gayet B, Salam E, Cherqui D, Vibert E, Scatton O, Nomi T, Oudafal N, Kawai T, Komatsu S, Okumura S, et al.
- Journal Title
  
  British Journal of Surgery
  
  Volume: 107 Issue: 3 Pages: 268-277
- DOI
  10.1002/bjs.11406
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16305
[Journal Article] Novel hybrid three-dimensional artificial liver using human induced pluripotent stem cells and a rat decellularized liver scaffold2019
- Author(s)
  Takahito Minami, Takamichi Ishii, Kentaro Yasuchika, Ken Fukumitsu, Satoshi Ogiso, Yuya Miyauchi, Hidenobu Kojima, Takayuki Kawai, Ryoya Yamaoka, Yu Oshima, Hiroshi Kawamoto, Maki Kotaka, Katsutaro Yasuda, Kenji Osafune, Shinji Uemoto
- Journal Title
  
  Regenerative therapy
  
  Volume: 10 Pages: 127-133
- DOI
  10.1016/j.reth.2019.03.002
- NAID
  120006719314
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08701, KAKENHI-PROJECT-16H05489, KAKENHI-PROJECT-18K16305
[Journal Article] Establishment of practical recellularized liver graft for blood perfusion using primary rat hepatocytes and liver sinusoidal endothelial cells2018
- Author(s)
  Kojima H.、Yasuchika K.、Fukumitsu K.、Ishii T.、Ogiso S.、Miyauchi Y.、Yamaoka R.、Kawai T.、Katayama H.、Yoshitoshi-Uebayashi E. Y.、Kita S.、Yasuda K.、Sasaki N.、Komori J.、Uemoto S.
- Journal Title
  
  American Journal of Transplantation
  
  Volume: 印刷中 Issue: 6 Pages: 1351-13559
- DOI
  10.1111/ajt.14666
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10592, KAKENHI-PROJECT-16H06903, KAKENHI-PROJECT-18K08701, KAKENHI-PROJECT-18K16305, KAKENHI-PROJECT-16H05489
[Journal Article] CD90 expression in human intrahepatic cholangiocarcinoma is associated with lymph node metastasis and poor prognosis.2018
- Author(s)
  Yamaoka R, Ishii T, Kawai T, Yasuchika K, Miyauchi Y, Kojima H, Katayama H, Ogiso S, Fukumitsu K, Uemoto S
- Journal Title
  
  J Surg Oncol.
  
  Volume: 4 Issue: 4 Pages: 664-674
- DOI
  10.1002/jso.25192
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08701, KAKENHI-PROJECT-18K16305, KAKENHI-PROJECT-16H05489, KAKENHI-PROJECT-16K10592
[Journal Article] A novel three-dimensional culture system maintaining the physiological extracellular matrix of fibrotic model livers accelerates progression of hepatocellular carcinoma cells2017
- Author(s)
  Miyauchi Yuya、Yasuchika Kentaro、Fukumitsu Ken、Ishii Takamichi、Ogiso Satoshi、Minami Takahito、Kojima Hidenobu、Yamaoka Ryoya、Katayama Hokahiro、Kawai Takayuki、Yoshitoshi-Uebayashi Elena Yukie、Kita Sadahiko、Yasuda Katsutaro、Sasaki Naoya、Uemoto Shinji
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1
- DOI
  10.1038/s41598-017-09391-y
- NAID
  120006364100
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10592, KAKENHI-PROJECT-16H05489, KAKENHI-PROJECT-16H06903
[Journal Article] Generation of non-viral, transgene-free hepatocyte like cells with piggyBac transposon.2017
- Author(s)
  Katayama H, et.al.
- Journal Title
  
  Sci Rep.
  
  Volume: 15 Issue: 1 Pages: 44498-44498
- DOI
  10.1038/srep44498
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06903, KAKENHI-PROJECT-16K10592, KAKENHI-PROJECT-16H05489
[Journal Article] Identification of keratin 19-positive cancer stem cells associating human hepatocellular carcinoma using CYFRA?21-12017
- Author(s)
  Kawai Takayuki、Yasuchika Kentaro、Ishii Takamichi、Katayama Hokahiro、Yoshitoshi Elena Yukie、Ogiso Satoshi、Minami Takahito、Miyauchi Yuya、Kojima Hidenobu、Yamaoka Ryoya、Kita Sadahiko、Yasuda Katsutaro、Sasaki Naoya、Fukumitsu Ken、Hatano Etsuro、Uemoto Shinji
- Journal Title
  
  Cancer Medicine
  
  Volume: 6 Issue: 11 Pages: 2531-2540
- DOI
  10.1002/cam4.1211
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10592, KAKENHI-PROJECT-16H06903
[Journal Article] SOX9 is a novel cancer stem cell marker surrogated by osteopontin in human hepatocellular carcinoma.2016
- Author(s)
  Kawai T, et.al.
- Journal Title
  
  Sci Rep.
  
  Volume: 26 Issue: 1 Pages: 30489-30489
- DOI
  10.1038/srep30489
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06903, KAKENHI-PROJECT-16K10592
[Presentation] Our strategies to achieve both continuously producing board-certificated HBP surgeons and reducing postoperative pancreatic fistula incidence in pancreatic surgery2023
- Author(s)
  河合隆之、仲野健三、井口公太、田浦康二朗、寺嶋宏明
- Organizer
  第35回日本肝胆膵外科学会学術集会
- Data Source
  KAKENHI-PROJECT-21K16461
[Presentation] The efficacy of newly-introduced pancreatic dissection method using DS clip in distal pancreatectomy2023
- Author(s)
  河合隆之、久野晃路、山本健人、仲野健三、奥知慶久、井口公太、田中英治、福田明輝、田浦康二朗、寺嶋宏明
- Organizer
  第78回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-21K16461
[Presentation] 当院における成人先天性胆道拡張症に対する腹腔鏡下手術導入と短期成績2023
- Author(s)
  河合隆之、中能玲央、大下恵樹、久野晃路、山本健人、仲野健三、奥知慶久、井口公太、田中英治、福田明輝、田浦康二朗、寺嶋宏明
- Organizer
  第36回日本内視鏡外科学会総会
- Data Source
  KAKENHI-PROJECT-21K16461
[Presentation] A retrospective analysis of our pancreatic transection method in laparoscopic distal pancreatectomy2022
- Author(s)
  河合隆之,奥田雄紀浩,久野晃路,山本健人,奥知慶久,井口公太,上村良,田中英治,福田明輝,寺嶋宏明
- Organizer
  第77回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-21K16461
[Presentation] 腹腔鏡下肝切除の知見を応用した、開腹肝切除における肝静脈周囲手術手技2022
- Author(s)
  河合隆之、久野晃路、井口公太、奥知慶久、奥田雄紀浩、上村良、田中英治、福田明輝、寺嶋宏明
- Organizer
  第30回日本消化器関連学会週間（JDDW2022）
- Data Source
  KAKENHI-PROJECT-21K16461
[Presentation] Impact of anatomical liver resection on patent survival in KRAS-wild type colorectal liver metastasis: A multicenter retrospective study2022
- Author(s)
  河合隆之,石井隆道,内田洋一朗,佐藤朝日,内藤滋俊,北口和彦,小松原隆司,井口公太,奥田雄紀浩,上村良,中村育夫,小木曾聡,福光剣,瀬尾智,藤川貴久,安近健太郎,廣瀬哲朗,財間正純,田浦康二朗,波多野悦朗, 寺嶋宏明
- Organizer
  第34回日本肝胆膵外科学会学術集会
- Data Source
  KAKENHI-PROJECT-21K16461
[Presentation] Survival and perioperative outcomes following pancreatic surgery in super-elderly pancreatic ductal adenocarcinoma patients2021
- Author(s)
  Takayuki Kawai, Kohta Iguchi, Yukihiro Okuda, Ryo Kamimura, Hiroaki Terajima
- Organizer
  15th IHPBA World Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K16461
[Presentation] Involvement of liver cirrhosis in keratin 19-positive cancer stem cells associating human hepatocellular carcinoma2020
- Author(s)
  Takayuki Kawai, Takamichi Ishii, Yuya Miyauchi, Satoshi Ogiso, Ken Fukumitsu, Shinji Uemoto
- Organizer
  The 14th World Congress of the International Hepato-Pancreato-Biliary Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16305
[Presentation] Caudal approach in laparoscopic liver resection for tumors in the Segment 12020
- Author(s)
  Takayuki Kawai, Kohta Iguchi, Ryo Kamimura, Hiroaki Terajima
- Organizer
  The 14th World Congress of the International Hepato-Pancreato-Biliary Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16305
[Presentation] KRAS野生型大腸癌同時性肝転移に対する系統的肝切除の腫瘍学的有用性2020
- Author(s)
  河合隆之，石井隆道，内田洋一朗，岡本共弘，井口公太，上村良，小木曾聡，福光剣，上本伸二，寺嶋宏明
- Organizer
  第75回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-18K16305
[Presentation] Laparoscopic two-stage hepatectomy for bilobar colorectal liver metastases; a multiinstitutional study2019
- Author(s)
  S.Okumura, C.Goumard, D.Fuks, T.Kawai, J.Danion, O.Soubrane, B.Gayet, O.Scatton
- Organizer
  The 2nd World Congress of the International Laparoscopic Liver Society (ILLS), Tokyo
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16305
[Presentation] Impact of liver cirrhosis in keratin 19-positive cancer stem cells associating human hepatocellular carcinoma2019
- Author(s)
  Takayuki Kawai, Takamichi Ishii, Yuya Miyauchi, Yu Oshima, Hiroshi Kawamoto, Takahito Minami, Hidenobu Kojima, Satoshi Ogiso, Ken Fukumitsu, Kentaro Yasuchika, Shinji Uemoto
- Organizer
  第31回日本肝胆膵外科学会学術集会、香川
- Data Source
  KAKENHI-PROJECT-18K16305
[Presentation] 大腸癌肝転移に対する腹腔鏡下肝切除の腫瘍学的有用性－術後化学療法導入までの期間に関する検討－2019
- Author(s)
  河合隆之、奥村晋也、Claire Goumard、Florence Jeune、Eric Savier、Jean-Christophe Vaillant、上本伸二、Olivier Scatton
- Organizer
  第119回日本外科学会定期学術集会、東京
- Data Source
  KAKENHI-PROJECT-18K16305
[Presentation] 両葉多発大腸癌肝転移に対する二期的肝切除－腹腔鏡下アプローチの有用性に関する検討－2019
- Author(s)
  河合隆之、奥村晋也、Claire Goumard、David Fuks、Brice Gayet、Olivier Scatton
- Organizer
  第74回日本消化器外科学会総会、東京
- Data Source
  KAKENHI-PROJECT-18K16305
[Presentation] Pure laparoscopic versus open hemihepatectomy: a critical assessment and realistic expectations. A propensity score based analysis of right and left hemihepatectomies from 9 European tertiary referral centers2019
- Author(s)
  F.Cipriani, M.Alzoubi, D.Fuks, F.Ratti, T.Kawai, G.Berardi, L.Barkhatov, P.Lainas, M.Van Der Poel, M.Faoury, M.Besselink, M.D'hondt, I.Dagher, B.Edwin, R.I.Troisi, O.Scatton, B.Gayet, L.Aldrighetti, M.Abu Hilal
- Organizer
  The 2nd World Congress of the International Laparoscopic Liver Society, Tokyo (ILLS)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16305
[Presentation] A novel culture system preserving natural scaffolds of fibrotic livers accelerates progression of hepatocellular carcinoma cells2018
- Author(s)
  Yuya Miyauchi, Kentaro Yasuchika Yu Oshima, Hiroshi Kawamoto, Takahito Minami, Hidenobu Kojima, Ryoya Yamaoka, Takayuki Kawai, Satoshi Ogiso, Ken Fukumitsu, Takamichi Ishii, Shinji Uemoto
- Organizer
  The Asian Pacific Association for the Study of the Liver Single topic Conference on HCC
- Invited
- Data Source
  KAKENHI-PROJECT-16H05489
[Presentation] Vascularization of recellularized liver graft2018
- Author(s)
  Hidenobu Kojima, Takamichi Ishii, Ken Fukumitsu, Yu Oshima, Hiroshi Kawamoto, Takahito Minami, Yuya Miyauchi, Ryoya Yamaoka, Takayuki Kawai, Shinji Uemoto
- Organizer
  8th International Forum of Liver Surgery
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08701
[Presentation] 肝細胞癌におけるkeratin 19陽性癌幹細胞を追跡するバイオマーカーとしての18F-FDGPETおよびkeratin 19 fragment(CYFRA 21-1)の役割2018
- Author(s)
  河合隆之, 石井隆道, 安近健太郎, 小木曾聡, 片山外大, 喜多貞彦, 南貴人, 宮内雄也, 小島秀信, 山岡竜也, 福光剣, 波多野悦朗, 上本伸二
- Organizer
  第118回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-16K10592
[Presentation] 肝細胞癌におけるkeratin 19陽性癌幹細胞を追跡するバイオマーカーとしての18F-FDGPETおよび血清keratin 19 fragment (CYFRA 21-1)の役割2018
- Author(s)
  河合隆之, 石井隆道, 安近健太郎, 小木曾聡, 南貴人, 宮内雄也, 小島秀信, 山岡竜也, 福光剣, 波多野悦朗, 上本伸二
- Organizer
  第118回日本外科学会定期学術集会、東京
- Data Source
  KAKENHI-PROJECT-18K16305
[Presentation] Tracking keratin 19-positive cancer stem cells using CYFRA 21-1 in hepatocellular carcinoma2018
- Author(s)
  Takayuki Kawai, Takamichi Ishii, Kentaro Yasuchika, Satoshi Ogiso, Takahito Minami, Yuya Miyauchi, Hidenobu Kojima, Ken Fukumitsu, Shinji Uemoto
- Organizer
  The 13th World Congress of the International Hepato-Pancreato-Biliary Association (IHPBA) 2018, Geneva, Switzerland
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16305
[Presentation] 再細胞化肝臓における内皮化の効果2018
- Author(s)
  小島秀信、石井隆道、福光　剣、大島　侑、川本浩史、南　貴人、宮内雄也、山岡竜也、河合隆之、上本伸二
- Organizer
  第54回肝臓学会総会
- Data Source
  KAKENHI-PROJECT-18K08701
[Presentation] ヒトiPS由来肝細胞様細胞とラット脱細胞化肝臓骨格を用いた臓器作製2018
- Author(s)
  南貴人，宮内雄也，小島秀信，大島侑，川本浩史，山岡竜也，河合隆之，上林エレーナ幸江，安田勝太郎，福光剣，石井隆道，岡島英明，
- Organizer
  第20回日本異種移植研究会
- Data Source
  KAKENHI-PROJECT-18K08701
[Presentation] ヒトiPS由来肝細胞様細胞とラット脱細胞化肝臓骨格を用いた臓器作製2018
- Author(s)
  南貴人，宮内雄也，小島秀信，大島侑，川本浩史，山岡竜也，河合隆之，上林エレーナ幸江，安田勝太郎，福光剣，石井隆道，岡島英明，海道利実，上本伸二
- Organizer
  第20回日本異種移植研究会
- Data Source
  KAKENHI-PROJECT-16H05489
[Presentation] Endothelialized liver scaffold-the impact of endothelial cells on recellularized liver-2018
- Author(s)
  Hidenobu Kojima, Takamichi Ishii, Ken Fukumitsu, Yu Oshima, Hiroshi Kawamoto, Takahito Minami, Yuya Miyauchi, Ryoya Yamaoka, Takayuki Kawai, Shinji Uemoto
- Organizer
  第30回日本肝胆膵外科学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05489
[Presentation] Identification of keratin 19-positive cancer stem cells associating human hepatocellular carcinoma using 18FFDGPET and CYFRA 21-12018
- Author(s)
  Takayuki Kawai, Takamichi Ishii, Kentaro Yasuchika, Satoru Seo, Satoshi Ogiso, Takahito Minami, Yuya Miyauchi, Ryoya Yamaoka, Hidenobu Kojima, Ken Fukumitsu, and Shinji Uemoto
- Organizer
  The International Liver Congress (EASL) 2018, Paris, France
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16305
[Presentation] Impact of endothelial cells on the engineered liver recellularized with primary rat hepatocytes2018
- Author(s)
  Hidenobu Kojima, Takamichi Ishii, Ken Fukumitsu, Yu Oshima, Hiroshi Kawamoto, Takahito Minami, Yuya Miyauchi, Ryoya Yamaoka, Takayuki Kawai, Shinji Uemoto
- Organizer
  13th IHPBA World Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08701
[Presentation] 再細胞化肝臓における内皮化の効果2018
- Author(s)
  小島秀信、石井隆道、福光　剣、大島　侑、川本浩史、南　貴人、宮内雄也、山岡竜也、河合隆之、上本伸二
- Organizer
  第54回肝臓学会総会
- Data Source
  KAKENHI-PROJECT-16H05489
[Presentation] Vascularization of recellularized liver graft2018
- Author(s)
  Hidenobu Kojima, Takamichi Ishii, Ken Fukumitsu, Yu Oshima, Hiroshi Kawamoto, Takahito Minami, Yuya Miyauchi, Ryoya Yamaoka, Takayuki Kawai, Shinji Uemoto
- Organizer
  8th International Forum of Liver Surgery
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05489
[Presentation] Endothelialized liver scaffold-the impact of endothelial cells on recellularized liver-2018
- Author(s)
  Hidenobu Kojima, Takamichi Ishii, Ken Fukumitsu, Yu Oshima, Hiroshi Kawamoto, Takahito Minami, Yuya Miyauchi, Ryoya Yamaoka, Takayuki Kawai, Shinji Uemoto
- Organizer
  第30回日本肝胆膵外科学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08701
[Presentation] Impact of endothelial cells on the engineered liver recellularized with primary rat hepatocytes2018
- Author(s)
  Hidenobu Kojima, Takamichi Ishii, Ken Fukumitsu, Yu Oshima, Hiroshi Kawamoto, Takahito Minami, Yuya Miyauchi, Ryoya Yamaoka, Takayuki Kawai, Shinji Uemoto
- Organizer
  13th IHPBA World Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05489
[Presentation] ヒトiPS由来肝細胞様細胞とラット脱細胞化肝臓骨格を用いた臓器作製2018
- Author(s)
  南　貴人、宮内　雄也、小島　秀信、大島　侑、川本　浩史、山岡　竜也、河合　隆之、上林エレーナ幸江、安田　勝太郎、福光　剣、石井　隆道、上本　伸二
- Organizer
  第20回日本異種移植研究会
- Data Source
  KAKENHI-PROJECT-16H05489
[Presentation] 肝移植を施行した肝細胞癌症例における癌幹細胞マーカーkeratin 19およびSOX9発現の意義2018
- Author(s)
  河合隆之、石井隆道、安近健太郎、川本浩史、大島侑、南貴人、宮内雄也、小島秀信、小木曾聡、福光剣、岡島英明、海道利美、上本伸二
- Organizer
  第54回日本移植学会総会、東京
- Data Source
  KAKENHI-PROJECT-18K16305
[Presentation] 細胞外基質による微小環境は肝細胞癌の不均一性に寄与する2018
- Author(s)
  宮内雄也　石井隆道　河合隆之　川本浩　大島侑　南貴人　小島秀信　山岡竜也　小木曾聡　福光:剣　岡島英明　海道利実　上本伸二
- Organizer
  肝癌研究会
- Data Source
  KAKENHI-PROJECT-16H05489
[Presentation] Development of precision medicine for keratin 19-positive hepatocellular carcinoma2018
- Author(s)
  Takayuki Kawai, Takamichi Ishii, Kentaro Yasuchika, Satoru Seo, Satoshi Ogiso, Yuya Miyauchi, Ryoya Yamaoka, Hidenobu Kojima, Ken Fukumitsu, Hideaki Okajima, Toshimi Kaido, and Shinji Uemoto
- Organizer
  The Asian Pacific Association for the Study of the Liver (APASL) Single Topic Conference on HCC 2018, Yokohama, Japan
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16305
[Presentation] A novel three-dimensional culture system, decellularized-tissue obtained from cirrhotic livers, enhances an epithelial-mesenchymal transition phenotype in HCC cells2017
- Author(s)
  Yuya Miyauchi, Kentaro Yasuchika, Ken Fukumitsu, Satoshi Ogiso, Hidenobu Kojima, Ryoya Yamaoka, Takayuki Kawai, Hokahiro Katayama, Elena Y Yoshitoshi, Sadahiko Kita, Katsutaro Yasuda, Naoya Sasaki, Takamichi Ishii, Junji Komori, Shinji Uemoto
- Organizer
  American college of Surgeons clinical congress
- Invited
- Data Source
  KAKENHI-PROJECT-16H05489
[Presentation] Biliary tree as a window for repopulation of the decellularized liver scaffold.2016
- Author(s)
  Satoshi Ogiso, Kentaro Yasuchika, Ken Fukumitsu, Takamichi Ishii, Hidenobu Kojima, Yuya Miyauchi, Ryoya Yamaoka, Hokahiro Katayama, Takayuki Kawai, Elena Yukie Yoshitoshi, Sadahiko Kita, Katsutaro Yasuda, Shinji Uemoto
- Organizer
  26th International congress of the transplantation society
- Place of Presentation
  Hong Kong
- Year and Date
  2016-08-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05489
[Presentation] Optimizing recellularization of decellularized whole-liver graft: from which route and with which cell?2016
- Author(s)
  Satoshi Ogiso, Kentaro Yasuchika, Ken Fukumitsu, Takamichi Ishii, Hidenobu Kojima, Yuya Miyauchi, Ryoya Yamaoka, Hokahiro Katayama, Takayuki Kawai, Sadahiko Kita, Shinji Uemoto
- Organizer
  The American College of Surgeons 102nd Clinical Congress
- Place of Presentation
  Washington DC, USA
- Year and Date
  2016-10-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05489
[Presentation] 肝細胞癌において血清OsteopontinはSOX9陽性癌幹細胞を追跡する新規バイオマーカーである2016
- Author(s)
  河合隆之
- Organizer
  第28回日本肝胆膵外科学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-16K10592
[Presentation] 肝胆膵外科治療におけるバイオマーカーの意義と展望 SOX9は肝細胞癌の新規癌幹細胞マーカーであり、血清Osteopontinにより追跡可能である2016
- Author(s)
  河合隆之
- Organizer
  第116回日本外科学会定期学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-16K10592

1. Ishii Takamichi (70456789)

# of Collaborated Projects: 4 results

# of Collaborated Products: 24 results
2. 上本伸二 (40252449)

# of Collaborated Projects: 4 results

# of Collaborated Products: 22 results
3. Fukumitsu Ken (70700516)

# of Collaborated Projects: 3 results

# of Collaborated Products: 20 results
4. Yasuchika Kentaro (00378895)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
5. 小木曾聡 (10804734)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
6. 波多野悦朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kawai Takayuki 河合 隆之

Research Projects

Research Products

Co-Researchers

肝細胞癌における癌幹細胞を標的とした新規治療戦略構築に関する研究Principal Investigator

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Genomic heterogeneity in hepatocellular carcinoma from a cancer stem cell perspective.

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Improvement of survival rate and ECM analysis using bio-engineered liver derived 3D scaffold

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Identification of the metastatic mechanism of keratin 19 positive cancer stem cells and novel therapeutic targets in hepatocellular carcinomaPrincipal Investigator

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Review Section

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Isolation of cancer stem cells of cholangiocarcinoma and identification of new therapeutic targets of cholangiocarcinoma

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Development of the transplantable artificial liver using iPS cells and decellularized liver

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[Journal Article] Integrated analyses of the genetic and clinicopathological features of cholangiolocarcinoma: cholangiolocarcinoma may be characterized by mismatch‐repair deficiency2024

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[Journal Article] Combined hepatocellular-cholangiocarcinoma compared to hepatocellular carcinoma and intrahepatic cholangiocarcinoma: Different survival, similar recurrence2024

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[Journal Article] Management of Patients Receiving Antiplatelet Therapy During Gastroenterological Surgery2023

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[Journal Article] Impact of anatomical liver resection on patient survival in KRAS-wild-type colorectal liver metastasis: A multicenter retrospective study2022

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[Journal Article] Clinical impact of lymphocyte/C-reactive protein ratio on postoperative outcomes in patients with rectal cancer who underwent curative resection2022

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[Journal Article] Laparoscopic versus open liver resection for intrahepatic cholangiocarcinoma: Report of an international multicenter cohort study with propensity score matching2022

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[Journal Article] Laparoscopic liver resection versus percutaneous radiofrequency ablation for small hepatocellular carcinoma2021

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[Journal Article] Preoperative risk score for prediction of long-term outcomes after hepatectomy for intrahepatic cholangiocarcinoma: Report of a collaborative, international-based, external validation study2020

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Kawai Takayuki 河合隆之