Shigemoto Yoko 重本蓉子

Researcher Number	00815384
Other IDs	https://orcid.org/0000-0003-2524-2498
Affiliation (Current)	2025: 国立研究開発法人国立精神・神経医療研究センター, 病院放射線診療部, 医師
Affiliation (based on the past Project Information) *help	2019 – 2023: 国立研究開発法人国立精神・神経医療研究センター, 病院放射線診療部, 医師
Review Section/Research Field	Principal Investigator Basic Section 52040:Radiological sciences-related
Keywords	Principal Investigator センチロイドスケール / PET / アミロイド / ネットワーク / メラニン / アルツハイマー病 / パーキンソン症候群 / 構造ネットワーク解析 / パーキンソン病 / 性別 / 年齢 / 健常者 / ネットワーク解析

MRIによる脳内連結解析とアミロイド蓄積の対比による認知症疾患の鑑別Principal Investigator
- Principal Investigator
  
  重本蓉子
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  National Center of Neurology and Psychiatry
Development of diagnostic assistance software for Parkinson's syndrome by brain network analysis using graph theoryPrincipal Investigator
- Principal Investigator
  
  Shigemoto Yoko
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  National Center of Neurology and Psychiatry

All 2023 2022 2021 2019

All Journal Article Presentation Book

[Book] Radiology-Nuclear Medicine Diagnostic Imaging: A Correlative Approach Diseases of the Central Nervous System (Pages: 163-193)2023
- Author(s)
  Hiroshi Matsuda, Eku Shimosegawa, Yoko Shigemoto, Noriko Sato, Hiroyuki Fujii, Fumio Suzuki, Yukio Kimura, Atsuhiko Sugiyama
- Total Pages
  912
- Publisher
  Wiley-Blackwell
- ISBN
  9781119603610
- Data Source
  KAKENHI-PROJECT-19K17157
[Journal Article] Age and Sex-Related Effects on Single-Subject Gray Matter Networks in Healthy Participants.2023
- Author(s)
  Shigemoto Y, Sato N, Maikusa N, Sone D, Ota M, Kimura Y, Chiba E, Okita K, Yamao T, Nakaya M, Maki H, Arizono E, Matsuda H.
- Journal Title
  
  J Pers Med.
  
  Volume: 13 Issue: 3 Pages: 419-419
- DOI
  10.3390/jpm13030419
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17157
[Journal Article] Correlation between the regional brain volume and glymphatic system activity in progressive supranuclear palsy.2023
- Author(s)
  Ota M, Sato N, Takahashi Y, Shigemoto Y, Kimura Y, Nakaya M, Chiba E, Matsuda H.
- Journal Title
  
  Dement Geriatr Cogn Disord.
  
  Volume: - Issue: 3 Pages: 177-183
- DOI
  10.1159/000530075
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17157, KAKENHI-PROJECT-20K08068, KAKENHI-PROJECT-21K07583
[Journal Article] Voxel-based analysis of age and gender effects on striatal [123I] FP-CIT binding in healthy Japanese adults2022
- Author(s)
  Shigemoto Yoko、Matsuda Hiroshi、Kimura Yukio、Chiba Emiko、Ohnishi Masahiro、Nakaya Moto、Maikusa Norihide、Ogawa Masayo、Mukai Yohei、Takahashi Yuji、Sako Kazuya、Toyama Hiroshi、Inui Yoshitaka、Taki Yasuyuki、Nagayama Hiroshi、Ono Kenjiro、Kono Atsushi、Sekiguchi Kenji、Hirano Shigeki、Sato Noriko
- Journal Title
  
  Annals of Nuclear Medicine
  
  Volume: 36 Issue: 5 Pages: 460-467
- DOI
  10.1007/s12149-022-01725-9
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07965, KAKENHI-PROJECT-19K17157
[Journal Article] Clinical and neuroimaging findings in patients with lissencephaly/subcortical band heterotopia spectrum: a magnetic resonance conventional and diffusion tensor study.2022
- Author(s)
  Chiba E, Kimura Y, Shimizu-Motohashi Y, Miyagawa N, Ota M, Shigemoto Y, Ohnishi M, Nakaya M, Nakagawa E, Sasaki M, Sato N.
- Journal Title
  
  Neuroradiology.
  
  Volume: 64 Issue: 4 Pages: 825-836
- DOI
  10.1007/s00234-021-02836-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K17157
[Journal Article] Harmonized Z-Scores Calculated from a Large-Scale Normal MRI Database to Evaluate Brain Atrophy in Neurodegenerative Disorders2022
- Author(s)
  Maikusa Norihide、Shigemoto Yoko、Chiba Emiko、Kimura Yukio、Matsuda Hiroshi、Sato Noriko
- Journal Title
  
  Journal of Personalized Medicine
  
  Volume: 12 Issue: 10 Pages: 1555-1555
- DOI
  10.3390/jpm12101555
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K12762, KAKENHI-PROJECT-19K17157
[Journal Article] Relationships Between the Deposition of Amyloid-β and Tau Protein and Glymphatic System Activity in Alzheimer's Disease: Diffusion Tensor Image Study.2022
- Author(s)
  Ota M, Sato N, Nakaya M, Shigemoto Y, Kimura Y, Chiba E, Yokoi Y, Tsukamoto T, Matsuda H.
- Journal Title
  
  J Alzheimers Dis.
  
  Volume: 90(1) Issue: 1 Pages: 295-303
- DOI
  10.3233/jad-220534
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08068, KAKENHI-PROJECT-21K07583, KAKENHI-PROJECT-19K17157
[Journal Article] MR Imaging Detection of CNS Lesions in Tuberous Sclerosis Complex: The Usefulness of T1WI with Chemical Shift Selective Images.2022
- Author(s)
  Fujii H, Sato N, Kimura Y, Mizutani M, Kusama M, Sumitomo N, Chiba E, Shigemoto Y, Takao M, Takayama Y, Iwasaki M, Nakagawa E, Mori H.
- Journal Title
  
  AJNR Am J Neuroradiol.
  
  Volume: 43 Issue: 8 Pages: 1202-1209
- DOI
  10.3174/ajnr.a7573
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K17157
[Journal Article] Upper cerebellar glucose hypermetabolism in patients with temporal lobe epilepsy and interictal psychosis2022
- Author(s)
  Sone Daichi、Sato Noriko、Shigemoto Yoko、Kimura Yukio、Matsuda Hiroshi
- Journal Title
  
  Epilepsia Open
  
  Volume: 7 Issue: 4 Pages: 657-664
- DOI
  10.1002/epi4.12645
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15720, KAKENHI-PROJECT-19K17157
[Journal Article] Frontal lobe-dominant cerebral blood flow reduction and atrophy can be progressive in Duchenne muscular dystrophy.2022
- Author(s)
  Mori-Yoshimura M. Aizawa K, Shigemoto Y, Ishihara N, Minami N, Nishino I, Yoshida S, Sato N, Takahashi Y.
- Journal Title
  
  Neuromuscul Disord.
  
  Volume: 32 Issue: 6 Pages: 477-485
- DOI
  10.1016/j.nmd.2022.02.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K17157
[Journal Article] Clinical impact of amyloid PET using 18F-florbetapir in patients with cognitive impairment and suspected Alzheimer's disease: a multicenter study.2022
- Author(s)
  Matsuda H, Okita K, Motoi Y, Mizuno T, Ikeda M, Sanjo N, Murakami K, Kambe T, Takayama T, Yamada K, Suehiro T, Matsunaga K, Yokota T, Tateishi U, Shigemoto Y, Kimura Y, Chiba E, Kawashima T, Tomo Y, Tachimori H, Kimura Y, Sato N
- Journal Title
  
  Ann Nucl Med
  
  Volume: 36 Issue: 12 Pages: 1039-1049
- DOI
  10.1007/s12149-022-01792-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07583, KAKENHI-PROJECT-17K10414, KAKENHI-PROJECT-19K17157
[Journal Article] Potential Treat-to-Target Approach for Methamphetamine Use Disorder: A Pilot Study of Adenosine 2A Receptor Antagonist With Positron Emission Tomography.2022
- Author(s)
  Okita K, Matsumoto T, Funada D, Murakami M, Kato K, Shigemoto Y, Sato N, Matsuda H.
- Journal Title
  
  Front Pharmacol.
  
  Volume: 13 Pages: 820447-820447
- DOI
  10.3389/fphar.2022.820447
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17157, KAKENHI-PROJECT-20K16634
[Journal Article] Free water derived by multi-shell diffusion MRI reflects tau/neuroinflammatory pathology in Alzheimer's disease2022
- Author(s)
  Nakaya M, Sato N, Matsuda H, Maikusa N, Shigemoto Y, Sone D, Yamao T, Ogawa M, Kimura Y, Chiba E, Ohnishi M, Kato K, Okita K, Tsukamoto T, Yokoi Y, Sakata M, Abe O.
- Journal Title
  
  Alzheimers Dement (N Y)
  
  Volume: 10;8(1) Issue: 1
- DOI
  10.1002/trc2.12356
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08068, KAKENHI-PROJECT-19K17157
[Journal Article] Gray matter structural networks related to 18 F-THK5351 retention in cognitively normal older adults and Alzheimer's disease patients2021
- Author(s)
  Yoko Shigemoto, Daichi Sone, Kyoji Okita, Norihide Maikusa, Tensho Yamao, Yukio Kimura, Fumio Suzuki, Hiroyuki Fujii, Koichi Kato, Noriko Sato, Hiroshi Matsuda
- Journal Title
  
  eNeurologicalSci
  
  Volume: 22 Pages: 100309-100309
- DOI
  10.1016/j.ensci.2021.100309
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17157, KAKENHI-PROJECT-18K07779, KAKENHI-PROJECT-20K08068, KAKENHI-PROJECT-21K07583
[Journal Article] Voxel-based correlation of 18F-THK5351 accumulation with gray matter structural networks in cognitively normal older adults2021
- Author(s)
  Yoko Shigemoto, Daichi Sone, Norihide Maikusa, Yukio Kimura, Fumio Suzuki, Hiroyuki Fujii, Noriko Sato, Hiroshi Matsuda
- Journal Title
  
  eNeurologicalSci
  
  Volume: 23 Pages: 100343-100343
- DOI
  10.1016/j.ensci.2021.100343
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17157, KAKENHI-PROJECT-21K07583
[Journal Article] Single-subject gray matter networks in temporal lobe epilepsy patients with hippocampal sclerosis2021
- Author(s)
  Shigemoto Yoko,Maikusa Norihide, Matsuda Hiroshi et al.
- Journal Title
  
  Epilepsy Research
  
  Volume: 177 Pages: 106766-106766
- DOI
  10.1016/j.eplepsyres.2021.106766
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K12025, KAKENHI-PROJECT-19K17157
[Presentation] 筋萎縮性側索硬化症における中心前回の血流定量化（第2報）2023
- Author(s)
  山川徹，齊藤勇二，重本蓉子，佐藤典子，髙橋祐二
- Organizer
  第64回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-19K17157
[Presentation] Alzheimer’s diseaseに対するFree water imagingとタウ/神経炎症PETとの相関関係2023
- Author(s)
  仲谷元, 佐藤典子, 松田博史, 舞草伯秀, 重本蓉子, 曽根大地, 山尾天翔, 木村有喜男, 千葉英美子, 阿部修
- Organizer
  第52回日本神経放射線学会
- Data Source
  KAKENHI-PROJECT-19K17157
[Presentation] MRI縦断画像解析法を用いたアルツハイマー病・軽度認知障害の脳萎縮評価2022
- Author(s)
  舞草伯秀, 木村有喜男, 重本蓉子, 千葉英美子, 松田博史, 佐藤典子
- Organizer
  第41回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19K17157
[Presentation] 筋萎縮性側索硬化症における中心前回の血流定量化2022
- Author(s)
  山川徹，齊藤勇二，重本蓉子，佐藤典子，髙橋祐二
- Organizer
  第63回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-19K17157
[Presentation] Alzheimer’s diseaseに対するFree water imagingとタウ/神経炎症PETとの相関関係2022
- Author(s)
  仲谷元, 佐藤典子, 松田博史, 舞草伯秀, 重本蓉子, 曽根大地, 山尾天翔, 木村有喜男, 千葉英美子, 阿部修
- Organizer
  第41回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19K17157
[Presentation] Voxel-based correlation of 18F-THK5351 accumulation with gray matter structural networks in cognitively normal older adults.2021
- Author(s)
  Shigemoto Y, Sone D, Maikusa N, Kimura Y, Suzuki F, Fujii H, Sato N, Matsuda H.
- Organizer
  AAIC 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17157
[Presentation] 大規模健常データベースを用いたHarmonized Z-scoreによるAD代理マーカーの検討.2021
- Author(s)
  舞草伯秀, 重本蓉子, 木村有喜男, 千葉英美子, 松田博史, 佐藤典子.
- Organizer
  第61回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-19K17157
[Presentation] NODDI, 構造ネットワーク, 脳年齢.2021
- Author(s)
  松田博史, 曽根大地, 重本蓉子, 佐藤典子.
- Organizer
  第40 回日本認知症学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K17157
[Presentation] 健常成人における123I-イオフルパン-SPECTのボクセル解析：年齢および性別が与える影響.2021
- Author(s)
  重本蓉子, 佐藤典子, 木村有喜男, 千葉英美子, 大西正紘, 仲谷元, 舞草伯秀, 向井洋平, 高橋祐二, 松田博史.
- Organizer
  第61回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-19K17157
[Presentation] タウ蛋白蓄積とコネクティビティの関連2019
- Author(s)
  重本蓉子
- Organizer
  第38回日本認知症学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K17157

1. MAIKUSA Norihide

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
2. SATO Noriko

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
3. 小野賢二郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 曽根大地

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 松田博史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shigemoto Yoko 重本 蓉子

Research Projects

Research Products

Co-Researchers

MRIによる脳内連結解析とアミロイド蓄積の対比による認知症疾患の鑑別Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of diagnostic assistance software for Parkinson's syndrome by brain network analysis using graph theoryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] Radiology-Nuclear Medicine Diagnostic Imaging: A Correlative Approach Diseases of the Central Nervous System (Pages: 163-193)2023

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Journal Article] Age and Sex-Related Effects on Single-Subject Gray Matter Networks in Healthy Participants.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Correlation between the regional brain volume and glymphatic system activity in progressive supranuclear palsy.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Voxel-based analysis of age and gender effects on striatal [123I] FP-CIT binding in healthy Japanese adults2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Clinical and neuroimaging findings in patients with lissencephaly/subcortical band heterotopia spectrum: a magnetic resonance conventional and diffusion tensor study.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Harmonized Z-Scores Calculated from a Large-Scale Normal MRI Database to Evaluate Brain Atrophy in Neurodegenerative Disorders2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Relationships Between the Deposition of Amyloid-β and Tau Protein and Glymphatic System Activity in Alzheimer's Disease: Diffusion Tensor Image Study.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] MR Imaging Detection of CNS Lesions in Tuberous Sclerosis Complex: The Usefulness of T1WI with Chemical Shift Selective Images.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Upper cerebellar glucose hypermetabolism in patients with temporal lobe epilepsy and interictal psychosis2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Frontal lobe-dominant cerebral blood flow reduction and atrophy can be progressive in Duchenne muscular dystrophy.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Clinical impact of amyloid PET using 18F-florbetapir in patients with cognitive impairment and suspected Alzheimer's disease: a multicenter study.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Potential Treat-to-Target Approach for Methamphetamine Use Disorder: A Pilot Study of Adenosine 2A Receptor Antagonist With Positron Emission Tomography.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Free water derived by multi-shell diffusion MRI reflects tau/neuroinflammatory pathology in Alzheimer's disease2022

Author(s)

Journal Title

Shigemoto Yoko 重本蓉子

[Presentation] 健常成人における123I-イオフルパン-SPECTのボクセル解析：年齢および性別が与える影響.2021