SAKURAI Yasuteru 櫻井康晃

Researcher Number	00818338
Other IDs
Affiliation (Current)	2025: 長崎大学, 熱帯医学研究所, 助教
Affiliation (based on the past Project Information) *help	2020 – 2023: 長崎大学, 熱帯医学研究所, 助教 2018 – 2020: 長崎大学, 感染症共同研究拠点, 助教
Review Section/Research Field	Principal Investigator Basic Section 49060:Virology-related / 0803:Pathology, infection/immunology, and related fields Except Principal Investigator Medium-sized Section 49:Pathology, infection/immunology, and related fields
Keywords	Principal Investigator 侵入阻害剤 / シュードウイルス / 細胞侵入過程 / クリミア・コンゴ出血熱ウイルス / 治療標的 / 病原性 / 表面糖タンパク質 / ダニ / 抗血清 / 宿主細胞侵入 … More / 複数のウイルス株 / シュードタイプウイルス / CCHFV / 膜融合 / 病原性発現機序 / 特異的阻害剤 / 化合物ライブラリー / ハザラウイルス / 阻害剤 / スクリーニング … More Except Principal Investigator コウモリ / ガボン / Virome / 新興感染症 / アフリカ / ウイルス / 人獣共通感染症 / SARS-CoV2 / 蛍光LAMP法 / 迅速診断法 / 海外研究拠点 / SARS-CoV-2 / COVID-19 / 新型コロナウイルス Less

中部アフリカに生息する野生動物のVirome解析による新興ウイルスの生態解明
- Principal Investigator
  
  安田二朗
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 49:Pathology, infection/immunology, and related fields
- Research Institution
  Nagasaki University
Analysis of molecular mechanisms of CCHFV cell entry and the pathogenicityPrincipal Investigator
- Principal Investigator
  
  Sakurai Yasuteru
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  Nagasaki University
Urgent research on COVID-19 utilizing infectious disease research stations in Asia
- Principal Investigator
  
  MORITA Kouichi
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Special Purposes
- Research Institution
  Nagasaki University
Analysis of host cell entry of Crimean-Congo hemorrhagic fever virus and identification of the therapeutic targetsPrincipal Investigator
- Principal Investigator
  
  SAKURAI Yasuteru
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0803:Pathology, infection/immunology, and related fields
- Research Institution
  Nagasaki University

All 2023 2022 2021 2020 2019

All Journal Article Presentation Patent

[Journal Article] Ebola Virus GP Activates Endothelial Cells via Host Cytoskeletal Signaling Factors2022
- Author(s)
  Moni Benedicte Mpia、Sakurai Yasuteru、Yasuda Jiro
- Journal Title
  
  Viruses
  
  Volume: 14 Issue: 1 Pages: 142-142
- DOI
  10.3390/v14010142
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07516
[Journal Article] Identification of novel chemical compounds targeting filovirus VP40-mediated particle production2022
- Author(s)
  Urata Shuzo、Omotuyi Olaposi Idowu、Izumisawa Ayako、Ishikawa Takeshi、Mizuta Satoshi、Sakurai Yasuteru、Mizutani Tatsuaki、Ueda Hiroshi、Tanaka Yoshimasa、Yasuda Jiro
- Journal Title
  
  Antiviral Research
  
  Volume: 199 Pages: 105267-105267
- DOI
  10.1016/j.antiviral.2022.105267
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07516, KAKENHI-PROJECT-21K07043, KAKENHI-PROJECT-21K07704, KAKENHI-PROJECT-21K12129, KAKENHI-PROJECT-20H04285
[Journal Article] Topoisomerase II as a Novel Antiviral Target against Panarenaviral Diseases2022
- Author(s)
  Afowowe Tosin Oladipo、Sakurai Yasuteru、Urata Shuzo、Zadeh Vahid Rajabali、Yasuda Jiro
- Journal Title
  
  Viruses
  
  Volume: 15 Issue: 1 Pages: 105-105
- DOI
  10.3390/v15010105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07516
[Journal Article] A screen of FDA-approved drugs with minigenome identified tigecycline as an antiviral targeting nucleoprotein of Crimean-Congo hemorrhagic fever virus.2022
- Author(s)
  Hirano M, Sakurai Y, Urata S, Kurosaki Y, Yasuda J, Yoshii K
- Journal Title
  
  Antiviral research
  
  Volume: - Pages: 105276-105276
- DOI
  10.1016/j.antiviral.2022.105276
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22353, KAKENHI-PROJECT-20H03136, KAKENHI-PROJECT-21K19191, KAKENHI-PROJECT-21KK0123, KAKENHI-PROJECT-20K07516, KAKENHI-PROJECT-22K15012, KAKENHI-PROJECT-21K20761
[Journal Article] 5-amino levulinic acid inhibits SARS-CoV-2 infection in vitro2021
- Author(s)
  Sakurai Yasuteru、Ngwe Tun Mya Myat、Kurosaki Yohei、Sakura Takaya、Inaoka Daniel Ken、Fujine Kiyotaka、Kita Kiyoshi、Morita Kouichi、Yasuda Jiro
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 545 Pages: 203-207
- DOI
  10.1016/j.bbrc.2021.01.091
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07516, KAKENHI-PROJECT-19K24679
[Journal Article] iPSC screening for drug repurposing identifies anti‐RNA virus agents modulating host cell susceptibility2021
- Author(s)
  Imamura Keiko、Sakurai Yasuteru、Enami Takako、Shibukawa Ran、Nishi Yohei、Ohta Akira、Shu Tsugumine、Kawaguchi Jitsutaro、Okada Sayaka、Hoenen Thomas、Yasuda Jiro、Inoue Haruhisa
- Journal Title
  
  FEBS Open Bio
  
  Volume: in press Issue: 5 Pages: 1452-1464
- DOI
  10.1002/2211-5463.13153
- NAID
  120007026449
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K24679, KAKENHI-PROJECT-20K07516
[Patent] 抗ウイルス剤2022
- Inventor(s)
  阿部高明、安田二朗、櫻井康晃
- Industrial Property Rights Holder
  阿部高明、安田二朗、櫻井康晃
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2022-094545
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-20K07516
[Patent] 新型コロナウイルス感染症（ＣＯＶＩＤ－１９）を治療及び／又は予防する方法、医薬2020
- Inventor(s)
  北潔、森田公一、安田二朗、櫻井康晃、他４名
- Industrial Property Rights Holder
  北潔、森田公一、安田二朗、櫻井康晃、他４名
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-20K07516
[Presentation] ミトコンドリア関連薬剤MA-5とその誘導体はSARS-CoV-2やその他RNAウイルスの感染を抑制する2023
- Author(s)
  櫻井康晃
- Organizer
  第70回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07516
[Presentation] クリミア・コンゴ出血熱ウイルスの細胞侵入過程評価系の開発と新規侵入阻害剤の同定2022
- Author(s)
  櫻井　康晃
- Organizer
  第63回日本熱帯医学会大会
- Data Source
  KAKENHI-PROJECT-20K07516
[Presentation] ペプチド模倣技術を用いたエボラ出血熱治療薬候補の開発2022
- Author(s)
  櫻井　康晃
- Organizer
  第69回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07516
[Presentation] Development of an efficient entry assay for Crimean-Congo hemorrhagic fever virus to identify novel entry inhibitors2021
- Author(s)
  Yasuteru Sakurai
- Organizer
  第68回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07516
[Presentation] クリミア・コンゴ出血熱ウイルスの細胞侵入過程評価系の開発と侵入阻害剤の同定2020
- Author(s)
  櫻井康晃
- Organizer
  9th Negative Strand Virus-Japan
- Data Source
  KAKENHI-PROJECT-19K21260
[Presentation] カルシウム活性化塩素チャネルTMEM16Aはエボラウイルス感染を制御する2019
- Author(s)
  櫻井康晃
- Organizer
  第67回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-19K21260
[Presentation] エボラウイルス研究とBSL4施設2019
- Author(s)
  櫻井康晃
- Organizer
  東北大学セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-19K21260
[Presentation] 米国 Texas Biomed におけるエボラウイルス研究と長崎大学 BSL4 施設の設置準備状況2019
- Author(s)
  櫻井康晃
- Organizer
  第19回日本バイオセーフティ学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K21260

1. 安田二朗 (10282518)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
2. MORITA Kouichi (40182240)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 長谷部太 (20253693)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 井上真吾 (00346925)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 川口寧 (60292984)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 松浦善治 (50157252)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 押谷仁 (80419994)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 森康子 (50343257)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 齋藤玲子 (30345524)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 木下貴明 (00803181)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 吉川禄助 (20816821)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 阿部遥 (90554353)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. YOSHII Kentaro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SAKURAI Yasuteru 櫻井 康晃

Research Projects

Research Products

Co-Researchers

中部アフリカに生息する野生動物のVirome解析による新興ウイルスの生態解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of molecular mechanisms of CCHFV cell entry and the pathogenicityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Urgent research on COVID-19 utilizing infectious disease research stations in Asia

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Analysis of host cell entry of Crimean-Congo hemorrhagic fever virus and identification of the therapeutic targetsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Ebola Virus GP Activates Endothelial Cells via Host Cytoskeletal Signaling Factors2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of novel chemical compounds targeting filovirus VP40-mediated particle production2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Topoisomerase II as a Novel Antiviral Target against Panarenaviral Diseases2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A screen of FDA-approved drugs with minigenome identified tigecycline as an antiviral targeting nucleoprotein of Crimean-Congo hemorrhagic fever virus.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 5-amino levulinic acid inhibits SARS-CoV-2 infection in vitro2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] iPSC screening for drug repurposing identifies anti‐RNA virus agents modulating host cell susceptibility2021

Author(s)

Journal Title

DOI

NAID

Data Source

[Patent] 抗ウイルス剤2022

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Industrial Property Number

Filing Date

Data Source

[Patent] 新型コロナウイルス感染症（ＣＯＶＩＤ－１９）を治療及び／又は予防する方法、医薬2020

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Data Source

[Presentation] ミトコンドリア関連薬剤MA-5とその誘導体はSARS-CoV-2やその他RNAウイルスの感染を抑制する2023

Author(s)

Organizer

Data Source

[Presentation] クリミア・コンゴ出血熱ウイルスの細胞侵入過程評価系の開発と新規侵入阻害剤の同定2022

Author(s)

Organizer

Data Source

[Presentation] ペプチド模倣技術を用いたエボラ出血熱治療薬候補の開発2022

SAKURAI Yasuteru 櫻井康晃