HONDA Ryo 本田諒

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Honda Ryo 本田諒

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Researcher Number	00820143
Other IDs	https://orcid.org/0000-0003-3698-5975
Affiliation (Current)	2025: 岐阜大学, 大学院連合創薬医療情報研究科, 准教授
Affiliation (based on the past Project Information) *help	2025: 岐阜大学, 大学院連合創薬医療情報研究科, 准教授 2021 – 2023: 岐阜大学, 大学院連合創薬医療情報研究科, 准教授 2019 – 2020: 岐阜大学, 大学院連合創薬医療情報研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 54010:Hematology and medical oncology-related / Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related / Basic Section 50020:Tumor diagnostics and therapeutics-related Except Principal Investigator Basic Section 47060:Clinical pharmacy-related / Basic Section 42020:Veterinary medical science-related
Keywords	Principal Investigator RAS阻害剤 / 分子標的薬 / 抗がん剤 / RAS / がん / 人工タンパク質 / 細胞膜透過性ペプチド / KRAS / 細胞膜透過性タンパク質 Except Principal Investigator 神経変性疾患 … More / 診断 / 脳神経疾患 / RT-Quic法 / 早期診断法 / タウタンパク質 / 進行性核上性麻痺 / RT-Quic / 抗体治療 / 分子シャペロン / 低分子化合物 / ALS / ミスフォールド Less

RAS選択的イムノトキシンの開発と悪性腫瘍治療薬等への応用：二重の分子標的薬の創製Principal Investigator
- Principal Investigator
  
  本田諒
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Gifu University
4リピートタウオパチーの予防・診断を指向したRT-QUIC法の開発と創薬研究
- Principal Investigator
  
  位田雅俊
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Gifu Pharmaceutical University
Development of a cell membrane permeable protein that inhibits oncogene RAS proteinsPrincipal Investigator
- Principal Investigator
  
  Honda Ryo
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  Gifu University
犬の変性性脊髄症を起こす変異SOD1蛋白質の立体構造解析と治療基盤の構築
- Principal Investigator
  
  神志那弘明
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Gifu University
Development of a new anticancer drug using a protein that has high affinity and specifically binds to mutant RasPrincipal Investigator
- Principal Investigator
  
  Honda Ryo
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Gifu University

All 2024 2023 2021 2020

All Journal Article Presentation Patent

[Journal Article] Specific inhibition of oncogenic RAS using cell-permeable RAS-binding domains2021
- Author(s)
  Nomura, T.K., Heishima, K., Sugito, N., Sugawara, R., Ueda, H., Akao, Y. and Honda, R.
- Journal Title
  
  Cell Chemical Biology
  
  Volume: - Issue: 11 Pages: 1581-1589.e6
- DOI
  10.1016/j.chembiol.2021.04.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07043, KAKENHI-PROJECT-19K16828
[Patent] 融合タンパク質2024
- Inventor(s)
  本田諒
- Industrial Property Rights Holder
  東海国立大学機構
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2024-049305
- Filing Date
  2024
- Data Source
  KAKENHI-PROJECT-22K15246
[Patent] 人工タンパク質、Ｒａｓ阻害剤及び抗がん剤2021
- Inventor(s)
  本田諒、赤尾幸博
- Industrial Property Rights Holder
  国立大学法人東海国立大学機構
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Overseas
- Data Source
  KAKENHI-PROJECT-19K16828
[Patent] 人工タンパク質、Ｒａｓ阻害剤及び抗がん剤2020
- Inventor(s)
  本田諒、赤尾幸博
- Industrial Property Rights Holder
  国立大学法人東海国立大学機構
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-137653
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-19K16828
[Presentation] オンラインシンポジウム：未踏のKRAS遺伝子に挑む2023
- Author(s)
  本田諒
- Organizer
  人工キメラタンパク質による KRAS 分子標的薬の開発の試み
- Data Source
  KAKENHI-PROJECT-22K15246
[Presentation] 2022年度【先端モデル動物支援プラットフォーム】成果発表会2023
- Author(s)
  本田諒
- Organizer
  細胞膜透過性タンパク質によるKRAS阻害剤の開発
- Data Source
  KAKENHI-PROJECT-22K15246
[Presentation] Structure-Based-Drug-Design of Small Molecule Inhibitors for Canine Superoxide Dismutase 1 Aggregation.2020
- Author(s)
  S.Kimura, Y.O.Kamatari, R.Honda, Z.Kato, S.Maeda, H.Kamishina.
- Organizer
  Sapporo Summer Symposium for One Health
- Data Source
  KAKENHI-PROJECT-20K06410
[Presentation] Molecular mechanism of protein aggregation of mutant SOD1 in canine ALS-like disease.2020
- Author(s)
  S.Kimura, R.Honda, Y.O.Kamatari, Z.Kato, H.Hara, S.Maeda, H.Kamishina.
- Organizer
  61th Annual Meeting of the Japanese Society of Neurology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06410
[Presentation] Molecular insights into protein aggregation of mutant Superoxide dismutase 1 in Degenerative Myelopathy.2020
- Author(s)
  S.Kimura, R.Honda, Y.O.Kamatari, Z.Kato, H.Hara, S.Maeda, H.Kamishina.
- Organizer
  American College of Veterinary Internal Medicine Forum
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06410

1. 神志那弘明 (50506847)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
2. 小畠結 (00805442)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 原英彰 (20381717)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. 鎌足雄司 (70342772)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. 加藤善一郎 (90303502)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. 位田雅俊 (70512424)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 下畑享良 (60361911)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 赤尾幸博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 上田浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HONDA Ryo 本田 諒

Honda Ryo 本田 諒

Research Projects

Research Products

Co-Researchers

RAS選択的イムノトキシンの開発と悪性腫瘍治療薬等への応用：二重の分子標的薬の創製Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

4リピートタウオパチーの予防・診断を指向したRT-QUIC法の開発と創薬研究

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a cell membrane permeable protein that inhibits oncogene RAS proteinsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

犬の変性性脊髄症を起こす変異SOD1蛋白質の立体構造解析と治療基盤の構築

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a new anticancer drug using a protein that has high affinity and specifically binds to mutant RasPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Specific inhibition of oncogenic RAS using cell-permeable RAS-binding domains2021

Author(s)

Journal Title

DOI

Data Source

[Patent] 融合タンパク質2024

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Industrial Property Number

Filing Date

Data Source

[Patent] 人工タンパク質、Ｒａｓ阻害剤及び抗がん剤2021

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Data Source

[Patent] 人工タンパク質、Ｒａｓ阻害剤及び抗がん剤2020

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Industrial Property Number

Filing Date

Data Source

[Presentation] オンラインシンポジウム：未踏のKRAS遺伝子に挑む2023

Author(s)

Organizer

Data Source

[Presentation] 2022年度【先端モデル動物支援プラットフォーム】成果発表会2023

Author(s)

Organizer

Data Source

[Presentation] Structure-Based-Drug-Design of Small Molecule Inhibitors for Canine Superoxide Dismutase 1 Aggregation.2020

Author(s)

Organizer

Data Source

[Presentation] Molecular mechanism of protein aggregation of mutant SOD1 in canine ALS-like disease.2020

Author(s)

Organizer

Data Source

[Presentation] Molecular insights into protein aggregation of mutant Superoxide dismutase 1 in Degenerative Myelopathy.2020

Author(s)

Organizer

Data Source

HONDA Ryo 本田諒

Honda Ryo 本田諒