Mitsuhashi Atsushi 三橋惇志

… Alternative Names

MITSUHASHI Atsushi 三橋惇志

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Researcher Number	00833732
Other IDs
Affiliation (Current)	2025: 徳島大学, 大学院医歯薬学研究部(医学域), 特任講師
Affiliation (based on the past Project Information) *help	2023 – 2024: 徳島大学, 大学院医歯薬学研究部(医学域), 特任講師 2019 – 2023: 徳島大学, 大学院医歯薬学研究部(医学域), 特任助教
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related Except Principal Investigator Basic Section 53030:Respiratory medicine-related / Basic Section 50010:Tumor biology-related / Basic Section 50020:Tumor diagnostics and therapeutics-related
Keywords	Principal Investigator 免疫チェックポイント阻害薬 / 肺がん / 血管新生 / がん / fibrocyte / ケモカイン / CXCL10/11 / 腫瘍血管新生 / 癌 / 免疫チェックポイント分子 / 線維細胞 / 血管新生阻害薬 … More Except Principal Investigator … More 線維細胞 / 樹状細胞 / がん免疫療法 / 1細胞解析 / 破骨細胞様マクロファージ / CD200 / 抗原提示細胞 / hot tumor誘導 / ヘパラナーゼ / 細胞外マトリクス / 腫瘍内投与 / 免疫チェックポイント阻害薬 / 間質性肺炎 / 非小細胞肺癌 / PD-L1抗体 / 血管新生阻害薬 / CXCLケモカイン / 薬剤耐性 / ケモカイン / 免疫チェックポイント / 血管新生 / 骨髄由来抑制細胞 / 肺がん Less

ヘパラナーゼ制御によるhot tumor誘導と新規がん複合免疫療法の創出
- Principal Investigator
  
  尾崎領彦
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  The University of Tokushima
腫瘍内線維細胞における時計遺伝子の機能解析と新規複合がん免疫療法開発への応用Principal Investigator
- Principal Investigator
  
  三橋惇志
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  The University of Tokushima
腫瘍内免疫療法を用いた新規複合がん免疫療法の効果規定因子を同定する試み
- Principal Investigator
  
  荻野広和
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  The University of Tokushima
肺がん・中皮腫における新たな抗原提示細胞の同定から革新的複合がん免疫療法への展開
- Principal Investigator
  
  西岡安彦
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  The University of Tokushima
Anti-angiogenic effects of PD-L1 blockade as a potential predictive biomarkerPrincipal Investigator
- Principal Investigator
  
  MITSUHASHI Atsushi
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  The University of Tokushima
Development of biomarkers related to drug resistance of angiogenesis inhibitors
- Principal Investigator
  
  Nokihara Hiroshi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  National Center for Global Health and Medicine
  The University of Tokushima
The role of fibrocyte in combination treatment of immune checkpoint inhibitor with antiangiogenic agentsPrincipal Investigator
- Principal Investigator
  
  MITSUHASHI Atsushi
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  The University of Tokushima
Development of novel combination immunotherapy against lung cancer and mesothelioma: establishment of immunological basis for clinic
- Principal Investigator
  
  NISHIOKA Yasuhiko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  The University of Tokushima

All 2024 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] Potential of fluoropyrimidine to be an immunologically optimal partner of immune checkpoint inhibitors through inducing immunogenic cell death for thoracic malignancies2023
- Author(s)
  Kozai Hiroyuki、Ogino Hirokazu、Mitsuhashi Atsushi、Nguyen Na Thi、Tsukazaki Yuki、Yabuki Yohei、Ozaki Ryohiko、Yoneda Hiroto、Sato Seidai、Hanibuchi Masaki、Shinohara Tsutomu、Nokihara Hiroshi、Nishioka Yasuhiko
- Journal Title
  
  Thoracic Cancer
  
  Volume: 15 Issue: 5 Pages: 369-378
- DOI
  10.1111/1759-7714.15200
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24340
[Journal Article] A multicenter, open-label, phase II trial of pemetrexed plus bevacizumab in elderly patients with previously untreated advanced or recurrent nonsquamous non-small cell lung cancer2023
- Author(s)
  Yabuki Y, Hanibuchi M, Takeuchi E, Haku T, Kanematsu T, Nishimura N, Toyoda Y, Mitsuhashi A, Otsuka K, Sato S, Goto H, Yoneda H, Ogino H, Nokihara H, Tsutomu S, Nishioka Y
- Journal Title
  
  Thorac Cancer
  
  Volume: 14(32) Issue: 32 Pages: 3232-3239
- DOI
  10.1111/1759-7714.15115
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23H00453, KAKENHI-PROJECT-23K24340
[Journal Article] Identification of fibrocyte cluster in tumors reveals the role in antitumor immunity by PD-L1 blockade2023
- Author(s)
  Mitsuhashi Atsushi、Koyama Kazuya、Ogino Hirokazu、Afroj Tania、Nguyen Na Thi、Yoneda Hiroto、Otsuka Kenji、Sugimoto Masamichi、Kondoh Osamu、Nokihara Hiroshi、Hanibuchi Masaki、Takizawa Hiromitsu、Shinohara Tsutomu、Nishioka Yasuhiko
- Journal Title
  
  Cell Reports
  
  Volume: 42 Issue: 3 Pages: 112162-112162
- DOI
  10.1016/j.celrep.2023.112162
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08542, KAKENHI-PROJECT-23K24340, KAKENHI-PROJECT-22K16302
[Journal Article] 1細胞解析による腫瘍内fibrocyteの同定2023
- Author(s)
  三橋惇志、西岡安彦
- Journal Title
  
  細胞
  
  Volume: 55 Pages: 55-59
- Data Source
  KAKENHI-PROJECT-23K24340
[Journal Article] Antipodoplanin antibody enhances the antitumor effects of CTLA‐4 blockade against malignant mesothelioma by natural killer cells2023
- Author(s)
  Yoneda Hiroto、Mitsuhashi Atsushi、Yoshida Aito、Ogino Hirokazu、Itakura Satoshi、Nguyen Na Thi、Nokihara Hiroshi、Sato Seidai、Shinohara Tsutomu、Hanibuchi Masaki、Abe Shinji、Kaneko Mika K.、Kato Yukinari、Nishioka Yasuhiko
- Journal Title
  
  Cancer Science
  
  Volume: 115 Issue: 2 Pages: 357-368
- DOI
  10.1111/cas.16046
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24340
[Journal Article] Analysis of the chemotactic factors for tumor?infiltrating fibrocytes and their prognostic significances in lung cancer2022
- Author(s)
  Tobiume Makoto, Mitsuhashi Atsushi, Saijo Atsuro, Ogino Hirokazu, Afroj Tania, Ogawa Hirohisa, Goto Hisatsugu, Sato Seidai, Abe Akane, Haji Keiko, Ozaki Ryohiko, Takizawa Hiromitsu, Nishioka Yasuhiko
- Journal Title
  
  Oncology Letters
  
  Volume: 24 Issue: 5 Pages: 417-417
- DOI
  10.3892/ol.2022.13537
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K24340
[Journal Article] Efficacy and safety of second‐line chemotherapy for patients with advanced non‐small cell lung cancer complicated by interstitial lung disease2022
- Author(s)
  Otsuka Kenji、Nokihara Hiroshi、Mitsuhashi Atsushi、Ozaki Ryohiko、Yabuki Yohei、Yoneda Hiroto、Ogino Hirokazu、Nishioka Yasuhiko
- Journal Title
  
  Thoracic Cancer
  
  Volume: 13 Issue: 21 Pages: 2978-2984
- DOI
  10.1111/1759-7714.14645
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08542
[Journal Article] S‐1 eliminates <scp>MDSCs</scp> and enhances the efficacy of <scp>PD</scp> ‐1 blockade via regulation of tumor‐derived Bv8 and <scp>S100A8</scp> in thoracic tumor2022
- Author(s)
  Nguyen Na T.、Mitsuhashi Atsushi、Ogino Hirokazu、Kozai Hiroyuki、Yoneda Hiroto、Afroj Tania、Sato Seidai、Nokihara Hiroshi、Shinohara Tsutomu、Nishioka Yasuhiko
- Journal Title
  
  Cancer Science
  
  Volume: 114 Issue: 2 Pages: 384-398
- DOI
  10.1111/cas.15620
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08542, KAKENHI-PROJECT-23K24340
[Journal Article] Correlation between immune-related adverse events and therapeutic effects of nivolumab in patients with malignant pleural mesothelioma2021
- Author(s)
  Yoneda Hiroto, Nokihara Hiroshi, Mitsuhashi Atsushi, Ozaki Ryohiko, Yabuki Yohei, Ogino Hirokazu, Otsuka Kenji, Nishioka Yasuhiko
- Journal Title
  
  BMC Pulmonary Medicine
  
  Volume: 21 Issue: 1
- DOI
  10.1186/s12890-021-01746-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03668
[Journal Article] Blockade of PD-1/PD-L1 Pathway Enhances the Antigen-Presenting Capacity of Fibrocytes2021
- Author(s)
  Afroj Tania、Mitsuhashi Atsushi、Ogino Hirokazu、Saijo Atsuro、Otsuka Kenji、Yoneda Hiroto、Tobiume Makoto、Nguyen Na Thi、Goto Hisatsugu、Koyama Kazuya、Sugimoto Masamichi、Kondoh Osamu、Nokihara Hiroshi、Nishioka Yasuhiko
- Journal Title
  
  The Journal of Immunology
  
  Volume: 206 Issue: 6 Pages: 1204-1214
- DOI
  10.4049/jimmunol.2000909
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03668
[Journal Article] Programmed death (PD)‐1/PD‐ligand 1 blockade mediates antiangiogenic effects by tumor‐derived CXCL10/11 as a potential predictive biomarker2021
- Author(s)
  Mitsuhashi Atsushi、Kondoh Kensuke、Horikawa Kazuki、Koyama Kazuya、Nguyen Na Thi、Afroj Tania、Yoneda Hiroto、Otsuka Kenji、Ogino Hirokazu、Nokihara Hiroshi、Shinohara Tsutomu、Nishioka Yasuhiko
- Journal Title
  
  Cancer Science
  
  Volume: 112 Issue: 12 Pages: 4853-4866
- DOI
  10.1111/cas.15161
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-18H05415, KAKENHI-PROJECT-19H03668, KAKENHI-PROJECT-20K08542, KAKENHI-PROJECT-21K15488
[Journal Article] 血管新生阻害剤に対する耐性獲得メカニズム2020
- Author(s)
  三橋惇志、西岡安彦
- Journal Title
  
  実験医学
  
  Volume: 38（増） Pages: 157-162
- Data Source
  KAKENHI-PROJECT-19H03668
[Journal Article] Anti-PD-1 antibody combined with chemotherapy suppresses the growth of mesothelioma by reducing myeloid-derived suppressor cells2020
- Author(s)
  Otsuka Kenji、Mitsuhashi Atsushi、Goto Hisatsugu、Hanibuchi Masaki、Koyama Kazuya、Ogawa Hirohisa、Ogino Hirokazu、Saijo Atsuro、Kozai Hiroyuki、Yoneda Hiroto、Tobiume Makoto、Kishuku Masatoshi、Ishizawa Keisuke、Nishioka Yasuhiko
- Journal Title
  
  Lung Cancer
  
  Volume: 146 Pages: 86-96
- DOI
  10.1016/j.lungcan.2020.05.023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03668
[Journal Article] 免疫チェックポイント阻害薬の効果を増強する併用療法2019
- Author(s)
  三橋　惇志、軒原　浩
- Journal Title
  
  分子呼吸器病
  
  Volume: 23 Pages: 49-53
- Data Source
  KAKENHI-PROJECT-19H03668
[Presentation] Fluoropyrimidine has a potential to be an immunologically optimal partner ofimmunotherapy for thoracic malignancies2024
- Author(s)
  Hirokazu Ogino、Nguyen Thi Na、Hiroyuki Kozai、Atsushi Mitsuhashi、Yuki Tsukazaki、Yohei Yabuki、Ryohiko Ozaki、Hiroshi Nokihara、Masaki Hanibuchi、Yasuhiko Nishioka
- Organizer
  第21回日本臨床腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-23K24340
[Presentation] 腫瘍内 fibrocyte の同定と制御による新規がん治療開発への橋渡し研究2023
- Author(s)
  三橋惇志、小山壱也、アフローズタニア、西條敦郎、飛梅亮、荻野広和、杉本正道、根東攝、軒原浩、西岡安彦
- Organizer
  第82回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24340
[Presentation] The novel prognostic system for the efficacy of immune checkpoint inhibitors in non-small cell lung cancer2023
- Author(s)
  Hirokazu Ogino、Kensuke Kondo、Atsushi Mitsuhashi、Yuki Tsukazaki、Ryohiko Ozaki、Yohei Yabuki、Hiroto Yoneda、Hiroshi Nokihara、Yasuhiko Nishioka
- Organizer
  第20回日本臨床腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-23K24340
[Presentation] 胸部腫瘍におけるfibrocyteの同定と新規治療標的としての展開2023
- Author(s)
  三橋惇志、荻野広和、米田浩人、軒原浩、西岡安彦
- Organizer
  第64回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-23K24340
[Presentation] 腫瘍内 fibrocyte 遊走・分化制御がもたらす腫瘍免疫微小環境への影響2023
- Author(s)
  三橋惇志、小山壱也、荻野広和、杉本正道、根東攝、軒原浩、西岡安彦
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K24340
[Presentation] 胸部悪性腫瘍において免疫チェックポイント阻害薬と併用すべき至適殺細胞性抗がん剤の同定を目指した免疫学的解析2023
- Author(s)
  荻野広和、Nguyen Na Thi、香西博之、三橋惇志、塚﨑佑貴、矢葺洋平、尾崎領彦、米田浩人、埴淵昌毅、西岡安彦
- Organizer
  第27回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-23K24340
[Presentation] 腫瘍内fibrocyteの同定と機能制御による新規複合がん免疫療法の開発2023
- Author(s)
  三橋惇志、荻野広和、Nguyen Na Thi、矢葺洋平、米田浩人、杉本正道、根東攝、軒原浩、西岡安彦
- Organizer
  第32回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-23K24340
[Presentation] 肺癌における腫瘍浸潤線維細胞の走化因子とその疾患予後に及ぼす影響についての解析2023
- Author(s)
  塚崎佑貴、三橋惇志、尾崎領彦、矢葺洋平、米田浩人、荻野広和、西岡安彦
- Organizer
  第27回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-23K24340
[Presentation] 悪性胸膜中皮腫に対する抗ポドプラニン抗体および抗CTLA-4抗体による複合がん免疫療法の検討2023
- Author(s)
  米田浩人、三橋惇志、荻野広和、軒原浩、阿部真治、金子美華、加藤幸成、西岡安彦
- Organizer
  第32回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-23K24340
[Presentation] The identification and analysis of fibrocyte regulating the tumor immune microenvironment2023
- Author(s)
  Atsushi Mitsuhashi、Kazuya Koyama、Tania Afroj、Atsuro Saijo、Makoto Tobiume、Hirokazu Ogino、Masamichi Sugimoto、Osamu Kondoh、Hiroshi Nokihara、Yasuhiko Nishioka
- Organizer
  he 9th Joint Meeting 2023 (Tokushima Univ., Gifu Univ., SNU, and IBS-KAIST)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24340
[Presentation] HIF1A 阻害による腫瘍細胞由来 CXCL10/11 制御を介した抗 PDL1 抗体への耐性克服2023
- Author(s)
  矢葺洋平、三橋惇志、荻野広和、Na T. Nguyen、米田浩人、尾崎領彦、塚崎佑貴、埴淵昌毅、軒原浩、西岡安彦
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K24340
[Presentation] 非小細胞肺癌症例における腫瘍浸潤線維細胞の走化因子と疾患予後との関連性についての解析2023
- Author(s)
  塚崎佑貴、飛梅亮、三橋惇志、尾崎領彦、矢葺洋平、米田浩人、荻野広和、埴淵昌毅、小川博久、滝沢宏光、西岡安彦
- Organizer
  第64回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-23K24340
[Presentation] IFN-g 反応性ケモカイン産生制御機序の解明と新規複合がん免疫療法への応用2023
- Author(s)
  矢葺洋平、三橋惇志、Nguyen Na Thi、荻野広和、米田浩人、尾崎領彦、西岡安彦
- Organizer
  第27回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-23K24340
[Presentation] Fibrocyte の分化制御による複合がん免疫療法への展開2023
- Author(s)
  三橋惇志、荻野広和、Nguyen Na Thi、米田浩人、矢葺洋平、杉本正道、根東攝、軒原浩、西岡安彦
- Organizer
  第27回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-23K24340
[Presentation] フッ化ピリミジンは胸部腫瘍の免疫原性細胞死を誘導し免疫チェックポイント阻害薬の至適併用薬となり得る2023
- Author(s)
  荻野広和、香西博之、三橋惇志、塚崎佑貴、矢葺洋平、尾崎領彦、米田浩人、埴淵昌毅、軒原浩、西岡安彦
- Organizer
  第64回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-23K24340
[Presentation] シングルセル解析を用いた肺線維症マウスモデルにおけるfibrocyteの検討2022
- Author(s)
  小山壱也, 三橋惇志, 今倉健, 村上行人, 香川耕造, 佐藤正大, 河野弘, 小川博久, 西岡安彦
- Organizer
  第62回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-23K24340
[Presentation] PD-1/PD-L1 blockade mediates antiangiogenic effects by tumorderived CXCL10/11 as a potential predictive biomarker2022
- Author(s)
  Atsushi Mitsuhashi, Hirokazu Ogino, Hiroshi Nokihara, Yasuhika Nishioka
- Organizer
  第81回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24340
[Presentation] PD-1/PD-L1 blockade mediates antiangiogenic effects by tumorderived CXCL10/11 as a potential predictive biomarker.2022
- Author(s)
  Atsushi Mitsuhashi, Hirokazu Ogino, Hiroshi Nokihara, Yasuhika Nishioka.
- Organizer
  第81回日本癌学会学術総会(Cancer Science Young Scientists Award Lectures)
- Invited
- Data Source
  KAKENHI-PROJECT-21K15488
[Presentation] Eliminates MDSCs and enhances the efficacy of immune checkpoint inhibitor in thoracic tumors2022
- Author(s)
  Na Thi Nguyen, Atsushi Mitsuhashi, Hirokazu Ogino, Hiroyuki Kozai, Hiroto Yoneda, Hiroshi Nokihara, Yasuhiko Nishioka
- Organizer
  第63回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-23K24340
[Presentation] 免疫チェックポイント阻害薬および血管新生阻害薬併用療法における腫瘍内fibrocyteの機能解析2022
- Author(s)
  三橋惇志, 荻野広和, Nguyen Thi Na, 米田浩人, 大塚憲司, 杉本正道, 根東攝, 軒原浩, 西岡安彦
- Organizer
  第26回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-23K24340
[Presentation] 悪性胸膜中皮腫に対する抗ポドプラニン抗体および抗CTLA-4抗体による複合がん免疫療法の検討2022
- Author(s)
  米田浩人, 三橋惇志, 荻野広和, 尾崎領彦, 矢葺洋平, 軒原浩, 阿部真治, 加藤幸成, 西岡安彦
- Organizer
  第26回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-23K24340
[Presentation] The examination of the second-line chemotherapy in SCLC patients with interstitial lung disease2022
- Author(s)
  Ryohiko Ozaki, Hiroshi Nokihara, Youhei Yabuki, Atsushi Mitsuhashi, Hiroto Yoneda, Kenji Otsuka, Hirokazu Ogino, Yasuhiko Nishioka
- Organizer
  ERS International Congress 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08542
[Presentation] Single Cell RNA-seq Analysis of Fibrocytes in Silica Induced Mouse Pulmonary Fibrosis Model2022
- Author(s)
  Kazuya Koyama, Hiroshi Kawano, Atsushi Mitsuhashi, Kojin Murakami, Takeshi Imakura, Yuya Yamashita, Keiko Haji, Kozo Kagawa, Seidai Sato, Hirohisa Ogawa, Yasuhilko Nishioka
- Organizer
  ATS 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24340
[Presentation] Second-line chemotherapy for extensive-disease small cell lung cancer with interstitial lung disease2022
- Author(s)
  Ryohiko Ozaki, Hiroshi Nokihara, Yohei Yabuki, Atsushi Mitsuhashi, Hiroto Yoneda, Kenji Otsuka, Hirokazu Ogino, Yasuhiko Nishioka
- Organizer
  第19回日本臨床腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03668
[Presentation] Fibrocyte drives antitumor immunity via T cell-costimulation in combination immunotherapy2022
- Author(s)
  Atsushi Mitsuhashi, Hirokazu Ogino, Masamichi Sugimoto, Hiroshi Nokihara, Yasuhiko Nishioka
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K24340
[Presentation] Evaluation of fibrocytes in silica-induced and bleomycin-induced pulmonary fibrosis model in mice by single cell RNA-seq analysis2022
- Author(s)
  Kazuya Koyama, Seidai Sato, Hiroshi Kawano, Atsushi Mitsuhashi, Kojin Murakami, Yuya Yamashita, Keiko Haji, Kozo Kagawa, Hirohisa Ogawa, Yasuhiko Nishioka
- Organizer
  APSR 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24340
[Presentation] PD-1/PD-L1 blockade mediates antiangiogenic effects by tumorderived CXCL10/11 as a potential predictive biomarker2022
- Author(s)
  Atsushi Mitsuhashi, Hirokazu Ogino, Hiroshi Nokihara, Yasuhika Nishioka
- Organizer
  第81回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08542
[Presentation] 免疫チェックポイント阻害薬および血管新生阻害薬併用療法におけるfibrocyteの役割2021
- Author(s)
  三橋惇志, 荻野広和, 西條敦郎，大塚憲司, 杉本正道，軒原浩, 西岡安彦
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03668
[Presentation] S-1 reduces myeloid-derived suppressor cells in murine mesothelioma model and enhances the anti-tumor activity of anti-PD-1 antibody.2021
- Author(s)
  Thi Na Nguyen, Atsushi Mitsuhashi, Hirokazu Ogino, Hiroyuki Kozai, Hiroto Yoneda, Tania Afroj, Kenji Otsuka, Hiroshi Nokihara, Yasuhiko Nishioka
- Organizer
  APSR 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03668
[Presentation] Antigen-presenting capacity of fibrocytes and its regulation by anti-PD-1/PD-L1 antibodies2021
- Author(s)
  Hirokazu Ogino, Tania Afroj, Atsushi Mitsuhashi, Atsuro Saijo, Kenji Otsuka, Hiroto Yoneda, Na Thi Nguyen, Kazuya Koyama, Masamichi Sugimoto, Osamu Kondoh, Hiroshi Nokihara, Yasuhiko Nishioka
- Organizer
  APSR 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03668
[Presentation] 抗PD-1/PD-L1抗体による腫瘍血管新生抑制メカニズムの解析と治療効果予測バイオマーカーとしての応用2021
- Author(s)
  三橋惇志, Tania Afroj, Nguyen Thi Na, 荻野広和, 米田浩人, 大塚憲司, 軒原浩, 西岡安彦
- Organizer
  第25回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03668
[Presentation] 肺がん肝転移におけるspheroid形成がん幹細胞様分画の役割2021
- Author(s)
  三橋惇志, 荻野広和, 米田浩人, 大塚憲司, 軒原浩, 西岡安彦
- Organizer
  第30回日本がん転移学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03668
[Presentation] 抗PD-1/PD-L1抗体による腫瘍血管新生抑制メカニズムの解析と治療効果予測バイオマーカーとしての応用2021
- Author(s)
  三橋惇志, Tania Afroj, Nguyen Thi Na, 荻野広和, 米田浩人, 大塚憲司, 軒原浩, 西岡安彦.
- Organizer
  第25回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-21K15488
[Presentation] Association of immune-related adverse events with therapeutic response to Nivolumab in patients with malignant pleural mesothelioma2021
- Author(s)
  Hiroto Yoneda, Hiroshi Nokihara, Atsushi Mitsuhashi, Ryohiko Ozaki, Yohei Yabuki, Hirokazu Ogino, Kenji Otsuka, Yasuhiko Nishioka
- Organizer
  APSR 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03668
[Presentation] 抗PD-1/PD-L1抗体による血管新生制御メカニズムの解析と治療効果予測バイオマーカーとしての応用2021
- Author(s)
  三橋惇志, 荻野広和, 米田浩人, 大塚憲司, 軒原浩, 西岡安彦
- Organizer
  第62回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03668
[Presentation] 抗PD-1/PD-L1抗体による血管新生制御メカニズムの解析と治療効果予測バイオマーカーとしての応用.2021
- Author(s)
  三橋惇志, 荻野広和, 米田浩人, 大塚憲司, 軒原浩, 西岡安彦.
- Organizer
  第62回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-21K15488
[Presentation] TS-1による腫瘍関連骨髄由来抑制細胞の制御を介した免疫チェックポイント阻害剤との併用効果の検討2021
- Author(s)
  Nguyen Thi Na, 三橋惇志, 香西博之, 米田浩人, Tania Afroj, 大塚憲司, 軒原浩, 西岡安彦
- Organizer
  第25回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03668
[Presentation] 進展型小細胞肺癌における予後規定因子2021
- Author(s)
  大塚憲司, 三橋惇志, 尾崎領彦, 矢葺洋平, 米田浩人, 荻野広和, 軒原浩, 竹内栄治, 杉浦八十生, 知花賢治, 田村厚久, 安宅信二, 西岡安彦
- Organizer
  第59回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03668
[Presentation] 悪性胸膜中皮腫患者におけるニボルマブの免疫関連有害事象と治療効果の相関性2021
- Author(s)
  米田浩人, 軒原浩, 三橋惇志, 尾崎領彦, 矢葺洋平, 荻野広和, 大塚憲司, 西岡安彦
- Organizer
  第59回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03668
[Presentation] 進展型小細胞肺癌の予後規定因子の検討2020
- Author(s)
  大塚憲司、三橋惇志、米田浩人、軒原浩、竹内栄治、知花賢治、安宅信二、田村厚久、西岡安彦
- Organizer
  第61回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03668
[Presentation] 免疫チェックポイント阻害薬および血管新生阻害薬併用療法における腫瘍内 fibrocyte-like cell の機能解析2020
- Author(s)
  三橋惇志、Tania Afroj、荻野広和、Nguyen Thi Na、米田浩人、香西博之、大塚憲司、杉本正道、根東攝、軒原浩、西岡安彦
- Organizer
  第24回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03668
[Presentation] The role of fibrocyte-like cells in combination treatment of immune checkpoint inhibitor with antiangiogenic agents.2020
- Author(s)
  Atsushi Mitsuhashi
- Organizer
  ERS International Congress 2020 Virtual
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16746
[Presentation] 肺癌において細胞障害性抗癌剤が免疫原性細胞死に与える影響についての検討2020
- Author(s)
  香西博之、三橋惇志、Nguyen Thi Na、Tania Afroj、米田浩人、大塚憲司、軒原浩、西岡安彦
- Organizer
  第24回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03668
[Presentation] 非小細胞肺癌における免疫チェックポイント阻害剤の予後予測因子の検討2020
- Author(s)
  近藤健介、軒原浩、三橋惇志、米田浩人、香西博之、大塚憲司、西岡安彦
- Organizer
  第24回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03668
[Presentation] 腫瘍免疫における線維細胞の免疫調節機能の検討2020
- Author(s)
  Tania Afroj、荻野広和、三橋惇志、米田浩人、香西博之、大塚憲司、軒原浩、安倍正博、西岡安彦
- Organizer
  第24回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03668
[Presentation] 免疫チェックポイント阻害薬および血管新生阻害薬併用療法における腫瘍内 fibrocyte-like cell の機能解析2020
- Author(s)
  三橋　惇志
- Organizer
  第24回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19K16746
[Presentation] マウス中皮腫細胞株皮下移植モデルにおける細胞障害性抗癌剤の腫瘍関連骨髄由来抑制細胞への影響2020
- Author(s)
  Nguyen Thi Na、三橋惇志、Tania Afroj、米田浩人、香西博之、大塚憲司、軒原浩、西岡安彦
- Organizer
  第24回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03668
[Presentation] 細胞障害性抗がん剤による腫瘍免疫原性細胞死誘導能の検討2020
- Author(s)
  香西博之、三橋惇志、米田浩人、大塚憲司、軒原浩、西岡安彦
- Organizer
  第58回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03668
[Presentation] ペメトレキセド投与後の皮疹に対する低用量デキサメタゾン予防効果の検討2020
- Author(s)
  三橋惇志、櫻田巧、合田光寬、座間味義人、米田浩人、大塚憲司、軒原浩、石澤啓介、西岡安彦
- Organizer
  第61回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03668
[Presentation] 免疫チェックポイント阻害薬および血管新生阻害薬併用療法における腫瘍内 fibrocyte-like cell の機能解析2020
- Author(s)
  三橋　惇志
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K16746
[Presentation] The role of fibrocyte-like cells in combination treatment of immune checkpoint inhibitor with antiangiogenic agents2020
- Author(s)
  Atsushi Mitsuhashi、Tania Afroj、Atsuro Saijo、Kenji Otsuka、Hiroto Yoneda、Kazuya Koyama、Masamichi Sugimoto、Osamu Kondoh、Hiroshi Nokihara、Yasuhiko Nishioka
- Organizer
  ERS International Congress 2020 Virtual
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03668
[Presentation] Analyses of immuno-modulatory function of fibrocytes in tumor immunity2019
- Author(s)
  Tania Afroj, Hirokazu Ogino, Makoto Tobiume, Hiroto Yoneda, Masatoshi Kisyuku, Atsuro Saijo, Atsushi Mitsuhashi, Kazuya Koyama, Hisatsugu Goto, Yasuhiko Nishioka
- Organizer
  第59回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-19H03668
[Presentation] 免疫チェックポイント阻害薬および血管新生阻害薬併用療法における腫瘍内fibrocyte-like cellの機能解析2019
- Author(s)
  三橋　惇志、後東　久嗣、荻野　広和、大塚　憲司、杉本　正道、根東　攝、西岡　安彦
- Organizer
  第23回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03668
[Presentation] 免疫チェックポイント阻害薬および血管新生阻害薬による複合がん免疫療法における腫瘍内fibrocytelike cellの機能解析2019
- Author(s)
  三橋　惇志、荻野　広和、木宿　昌俊、大塚　憲司、軒原　浩、西岡　安彦
- Organizer
  第32回日本バイオセラピィ学会学術集会総会
- Data Source
  KAKENHI-PROJECT-19H03668
[Presentation] 免疫チェックポイント阻害薬および血管新生阻害薬による複合がん免疫療法における腫瘍内fibrocyte-like cellの機能解析2019
- Author(s)
  三橋惇志、荻野広和、大塚憲司、木宿昌俊、西岡安彦
- Organizer
  第32回日本バイオセラピィ学会学術集会総会
- Data Source
  KAKENHI-PROJECT-19K16746
[Presentation] 血管新生阻害薬耐性とその克服2019
- Author(s)
  西岡　安彦、荻野　広和、三橋　惇志
- Organizer
  第23回日本がん分子標的治療学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03668
[Presentation] 免疫チェックポイント阻害薬および血管新生阻害薬併用療法における腫瘍内fibrocyt2019
- Author(s)
  三橋惇志、後東久嗣、荻野広和、大塚憲司、杉本正道、根東攝、西岡安彦
- Organizer
  第23回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19K16746

1. 荻野広和 (20745294)

# of Collaborated Projects: 4 results

# of Collaborated Products: 23 results
2. NISHIOKA Yasuhiko (70274199)

# of Collaborated Projects: 2 results

# of Collaborated Products: 55 results
3. Nokihara Hiroshi (00505919)

# of Collaborated Projects: 2 results

# of Collaborated Products: 29 results
4. 佐藤正大 (80530899)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
5. 大塚憲司 (70776856)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 木宿昌俊 (90597501)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 尾崎領彦 (70991561)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 小山壱也 (90724089)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
9. HORIKAWA Kazuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 西村直樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Mitsuhashi Atsushi 三橋 惇志

MITSUHASHI Atsushi 三橋 惇志

Research Projects

Research Products

Co-Researchers

ヘパラナーゼ制御によるhot tumor誘導と新規がん複合免疫療法の創出

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腫瘍内線維細胞における時計遺伝子の機能解析と新規複合がん免疫療法開発への応用Principal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

腫瘍内免疫療法を用いた新規複合がん免疫療法の効果規定因子を同定する試み

Principal Investigator

Project Period (FY)

Research Category

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Research Institution

肺がん・中皮腫における新たな抗原提示細胞の同定から革新的複合がん免疫療法への展開

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Anti-angiogenic effects of PD-L1 blockade as a potential predictive biomarkerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of biomarkers related to drug resistance of angiogenesis inhibitors

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of fibrocyte in combination treatment of immune checkpoint inhibitor with antiangiogenic agentsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of novel combination immunotherapy against lung cancer and mesothelioma: establishment of immunological basis for clinic

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

[Journal Article] Potential of fluoropyrimidine to be an immunologically optimal partner of immune checkpoint inhibitors through inducing immunogenic cell death for thoracic malignancies2023

Author(s)

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Data Source

[Journal Article] A multicenter, open-label, phase II trial of pemetrexed plus bevacizumab in elderly patients with previously untreated advanced or recurrent nonsquamous non-small cell lung cancer2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of fibrocyte cluster in tumors reveals the role in antitumor immunity by PD-L1 blockade2023

Author(s)

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DOI

Data Source

[Journal Article] 1細胞解析による腫瘍内fibrocyteの同定2023

Author(s)

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Data Source

[Journal Article] Antipodoplanin antibody enhances the antitumor effects of CTLA‐4 blockade against malignant mesothelioma by natural killer cells2023

Author(s)

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DOI

Data Source

[Journal Article] Analysis of the chemotactic factors for tumor?infiltrating fibrocytes and their prognostic significances in lung cancer2022

Author(s)

Journal Title

Mitsuhashi Atsushi 三橋惇志

MITSUHASHI Atsushi 三橋惇志