Mochida Kyoko 持田京子

Researcher Number	00834417
Other IDs
Affiliation (Current)	2025: 地方独立行政法人大阪府立病院機構大阪母子医療センター(研究所), 病因病態部門, 流動研究員
Affiliation (based on the past Project Information) *help	2019 – 2023: 地方独立行政法人大阪府立病院機構大阪母子医療センター(研究所), 病因病態部門, 流動研究員
Review Section/Research Field	Principal Investigator Basic Section 52050:Embryonic medicine and pediatrics-related Except Principal Investigator Basic Section 44020:Developmental biology-related
Keywords	Principal Investigator 二分脊椎 / 表皮分化 / 核-細胞質輸送 / 哺乳動物 / 先天異常 / 遺伝子改変マウス / 口蓋裂疾患 / 遺伝子欠損マウス / マウス / 表皮癒合 … More / 神経管閉鎖不全 / 疾患モデルマウス / 口唇口蓋裂 / 上皮癒合 … More Except Principal Investigator 脱落膜 / 原子間力顕微鏡 / ECM / 細胞外基質 / マウス Less

Identification of partner molecules that bind directly to GRHL3 factors during epidermal differentiation.Principal Investigator
- Principal Investigator
  
  持田京子
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Osama Woman's and Children's Hospital
ほ乳動物胚の成長に必要な子宮内環境の解明
- Principal Investigator
  
  上田陽子
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44020:Developmental biology-related
- Research Institution
  Osama Woman's and Children's Hospital
Elucidation of the common etiology of spina bifida and cleft palate caused by epithelial fusion defects.Principal Investigator
- Principal Investigator
  
  Mochida Kyoko
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Osama Woman's and Children's Hospital

All 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] BET proteins are essential for the specification and maintenance of the epiblast lineage in mouse preimplantation embryos.2022
- Author(s)
  Tsume-Kajioka M, Kimura-Yoshida C, Mochida K, Ueda Y, Matsuo I
- Journal Title
  
  BMC Biology
  
  Volume: 20 Issue: 1 Pages: 01251-0
- DOI
  10.1186/s12915-022-01251-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10202, KAKENHI-PROJECT-18K15738, KAKENHI-PROJECT-19K06685, KAKENHI-PROJECT-19K08291, KAKENHI-PROJECT-21K06194, KAKENHI-PROJECT-21K19467, KAKENHI-PROJECT-19H03238, KAKENHI-PUBLICLY-21H05794
[Journal Article] USP39 is essential for mammalian epithelial morphogenesis through upregulation of planar cell polarity components2022
- Author(s)
  Kimura-Yoshida C, Mochida K, Kanno SI, Matsuo I.
- Journal Title
  
  Communications Biology
  
  Volume: 378 Issue: 1 Pages: 1-18
- DOI
  10.1038/s42003-022-03254-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06685, KAKENHI-PROJECT-19K08291, KAKENHI-PROJECT-21K19467, KAKENHI-PUBLICLY-21H05794, KAKENHI-PROJECT-19H03238
[Journal Article] Intrauterine pressures adjusted by Reichert’s membrane are crucial for early mouse morphogenesis.2020
- Author(s)
  Yoko Ueda, Chiharu Kimura-Yoshida, Kyoko Mochida, Mami Tsume, Yoshitaka Kameo, Taiji Adachi, Olivier Lefebvre, Ryuji Hiramatsu and Isao Matsuo
- Journal Title
  
  Cell Reports
  
  Volume: 31 Issue: 7 Pages: 107637-107637
- DOI
  10.1016/j.celrep.2020.107637
- NAID
  120006951713
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04771, KAKENHI-PROJECT-17K10202, KAKENHI-PROJECT-19K06397, KAKENHI-ORGANIZER-15H05856, KAKENHI-PUBLICLY-19H04798, KAKENHI-PROJECT-19H03238, KAKENHI-INTERNATIONAL-15K21726, KAKENHI-PROJECT-19K06685, KAKENHI-PROJECT-19K08291, KAKENHI-PROJECT-18K15738
[Presentation] 神経管閉鎖に働く特異な表皮細胞を誘導する新規因子の探索2023
- Author(s)
  木村‐吉田　千春, 持田　京子，菅野新一郎, 松尾　勲
- Organizer
  第126回日本小児科学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08291
[Presentation] USP39 is essential for mammalian epithelial morphogenesis through upregulation of planar cell polarity components.2023
- Author(s)
  Chiharu Kmura-Yoshida, Kyoko Mochida, Shin-Ichiro Kanno, Isao Matsuo
- Organizer
  The 56th annual meeting of the Japanese Society of Developmental Biologists
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08291
[Presentation] 哺乳動物の上皮形成過程において、脱ユビキチン化酵素USP39因子は平面内極性(PCP経路）構成因子を活性化することで機能する2022
- Author(s)
  木村-吉田千春、持田京子、菅野新一郎、松尾勲
- Organizer
  第45回日本分子生物学会年会　（幕張メッセ）
- Data Source
  KAKENHI-PROJECT-19K08291
[Presentation] Mechanical role of Reichert's membrane for early mouse morphogenesis in utero.2021
- Author(s)
  Yoko Ueda, Chiharu Kimura-Yoshida, Kyoko Mochida, Mami Tsume, Ryuji Hiramatsu, and Isao Matsuo
- Organizer
  第54回発生生物学会ポスター発表
- Data Source
  KAKENHI-PROJECT-21K06194
[Presentation] Principles in the symmetry breaking in animal and plant development Embryo shape change from sphere to egg-cylinder mediated by intrauterine pressures is crucial for mouse primary axis formation.2020
- Author(s)
  Yoko Ueda, Chiharu Kimura-Yoshida, Kyoko Mochida, Mami Tsume, Yoshitaka Kameo, Taiji Adachi, Lefebvre Olivier, Ryuji Hiramatsu, Isao Matsuo
- Organizer
  第43回日本分子生物学会年会 MBSJ2020
- Data Source
  KAKENHI-PROJECT-19K08291
[Presentation] BRD4はJAK/STAT標的遺伝子の転写活性化を介してマウス着床前胚におけるエピブラストの特異化に必要である2020
- Author(s)
  爪麻美、木村（吉田）千春、上田陽子、持田京子、松尾勲
- Organizer
  第43回日本分子生物学会年会 MBSJ2020
- Data Source
  KAKENHI-PROJECT-19K08291
[Presentation] GRHL3タンパクの細胞質における局在が上皮細胞の分化過程から形態形成過程へと進行させる2019
- Author(s)
  Kimura-Yoshida C., Mochida K., Nakaya M., Mizutani T., Matsuo I.
- Organizer
  第52回日本発生生物学会大会　（大阪）
- Data Source
  KAKENHI-PROJECT-19K08291

1. 吉田千春 (60360666)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
2. 上田陽子 (50755808)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. 松尾勲

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Mochida Kyoko 持田 京子

Research Projects

Research Products

Co-Researchers

Identification of partner molecules that bind directly to GRHL3 factors during epidermal differentiation.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ほ乳動物胚の成長に必要な子宮内環境の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the common etiology of spina bifida and cleft palate caused by epithelial fusion defects.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] BET proteins are essential for the specification and maintenance of the epiblast lineage in mouse preimplantation embryos.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] USP39 is essential for mammalian epithelial morphogenesis through upregulation of planar cell polarity components2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Intrauterine pressures adjusted by Reichert’s membrane are crucial for early mouse morphogenesis.2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Presentation] 神経管閉鎖に働く特異な表皮細胞を誘導する新規因子の探索2023

Author(s)

Organizer

Data Source

[Presentation] USP39 is essential for mammalian epithelial morphogenesis through upregulation of planar cell polarity components.2023

Author(s)

Organizer

Data Source

[Presentation] 哺乳動物の上皮形成過程において、脱ユビキチン化酵素USP39因子は平面内極性(PCP経路）構成因子を活性化することで機能する2022

Author(s)

Organizer

Data Source

[Presentation] Mechanical role of Reichert's membrane for early mouse morphogenesis in utero.2021

Author(s)

Organizer

Data Source

[Presentation] Principles in the symmetry breaking in animal and plant development Embryo shape change from sphere to egg-cylinder mediated by intrauterine pressures is crucial for mouse primary axis formation.2020

Author(s)

Organizer

Data Source

[Presentation] BRD4はJAK/STAT標的遺伝子の転写活性化を介してマウス着床前胚におけるエピブラストの特異化に必要である2020

Author(s)

Organizer

Data Source

[Presentation] GRHL3タンパクの細胞質における局在が上皮細胞の分化過程から形態形成過程へと進行させる2019

Author(s)

Organizer

Data Source

Mochida Kyoko 持田京子