kawashima keigo 河島圭吾

… Alternative Names

河島圭吾カワシマケイゴ

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Researcher Number	00852104
Other IDs
Affiliation (Current)	2025: 名古屋市立大学, 医薬学総合研究院(医学), 研究員 2025: 国立健康危機管理研究機構, ウイルス第二部, 主任研究員 2025: 国立健康危機管理研究機構, 国立感染症研究所ワクチン開発研究センター, 主任研究員
Affiliation (based on the past Project Information) *help	2025: 国立健康危機管理研究機構, ウイルス第二部, 主任研究官 2024: 名古屋市立大学, 医薬学総合研究院(医学), 研究員 2020 – 2021: 名古屋市立大学, 医薬学総合研究院(医学), 助教
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related
Keywords	Principal Investigator B型肝炎ウイルス / 共刺激シグナル / CD8+T細胞 / HBV特異的T細胞 / T細胞 / HBV / B型肝炎

Elucidating the mechanisms of sustained HBV suppression through co-stimulatory signaling activationPrincipal Investigator
- Principal Investigator
  
  河島圭吾
- Project Period (FY)
  2025 – 2026
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Japan Institute for Health Security
Selective stimulation of intrahepatically primed HBV-specific T cells for curing hepatitis BPrincipal Investigator
- Principal Investigator
  
  河島圭吾
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Nagoya City University

All 2021 2020

All Journal Article Presentation

[Journal Article] Restoration of type I interferon signaling in intrahepatically primed CD8+ T cells promotes functional differentiation2021
- Author(s)
  Kawashima Keigo、Isogawa Masanori、Onishi Masaya、Baudi Ian、Saito Satoru、Nakajima Atsushi、Fujita Takashi、Tanaka Yasuhito
- Journal Title
  
  JCI Insight
  
  Volume: 6 Issue: 3
- DOI
  10.1172/jci.insight.145761
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08313, KAKENHI-PROJECT-20K17028
[Journal Article] Interferon signaling suppresses the unfolded protein response and induces cell death in hepatocytes accumulating hepatitis B surface antigen2021
- Author(s)
  Baudi Ian、Isogawa Masanori、Moalli Federica、Onishi Masaya、Kawashima Keigo、Ishida Yuji、Tateno Chise、Sato Yusuke、Harashima Hideyoshi、Ito Hiroyasu、Ishikawa Tetsuya、Wakita Takaji、Iannacone Matteo、Tanaka Yasuhito
- Journal Title
  
  PLOS Pathogens
  
  Volume: 17 Issue: 5 Pages: e1009228-e1009228
- DOI
  10.1371/journal.ppat.1009228
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17028, KAKENHI-PROJECT-20K08313
[Journal Article] HBV-Specific CD8+ T-Cell Tolerance in the Liver2021
- Author(s)
  Baudi Ian、Kawashima Keigo、Isogawa Masanori
- Journal Title
  
  Frontiers in immunology
  
  Volume: 12 Pages: 721975-721975
- DOI
  10.3389/fimmu.2021.721975
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17028, KAKENHI-PROJECT-20K08313
[Journal Article] Inhibitory Effect of a Human MicroRNA, miR-6133-5p, on the Fibrotic Activity of Hepatic Stellate Cells in Culture2020
- Author(s)
  Hamada-Tsutsumi Susumu、Onishi Masaya、Matsuura Kentaro、Isogawa Masanori、Kawashima Keigo、Sato Yusuke、Tanaka Yasuhito
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Issue: 19 Pages: 7251-7251
- DOI
  10.3390/ijms21197251
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09435, KAKENHI-PROJECT-20K08313, KAKENHI-PROJECT-20K08314, KAKENHI-PROJECT-20K17028, KAKENHI-PROJECT-19H03640
[Journal Article] B型肝炎診療の現在　B型肝炎に対する新規薬剤の開発状況2020
- Author(s)
  河島圭吾、田中靖人
- Journal Title
  
  消化器・肝臓内科
  
  Volume: 8 Pages: 197-204
- Data Source
  KAKENHI-PROJECT-20K17028
[Presentation] Functional cure を目指した OX40 刺激による HBV 特異的 CD8+T 細胞の賦活化2021
- Author(s)
  五十川正記, 河島圭吾, 田中靖人
- Organizer
  第57回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-20K17028
[Presentation] Suppression of intrahepatic hepatitis B surface antigen (HBsAg) prevents interferon mediated liver injury2020
- Author(s)
  Baudi Ian、Isogawa Masanori、Kawashima Keigo、Tanaka Yasuhito
- Organizer
  The Liver Meeting Digital Experience, American Association for the Study of Liver Diseases (AASLD 2020)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17028
[Presentation] CD8+T細胞のOX40シグナル刺激による持続的なHBs抗原抑制2020
- Author(s)
  五十川正記、河島圭吾、田中靖人
- Organizer
  第28回日本消化器関連学会週間（JDDW2020）
- Data Source
  KAKENHI-PROJECT-20K17028

1. MATSUURA Kentarou

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 五十川正記

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

kawashima keigo 河島 圭吾

河島 圭吾 カワシマ ケイゴ

Research Projects

Research Products

Co-Researchers

Elucidating the mechanisms of sustained HBV suppression through co-stimulatory signaling activationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Selective stimulation of intrahepatically primed HBV-specific T cells for curing hepatitis BPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Restoration of type I interferon signaling in intrahepatically primed CD8+ T cells promotes functional differentiation2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Interferon signaling suppresses the unfolded protein response and induces cell death in hepatocytes accumulating hepatitis B surface antigen2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] HBV-Specific CD8+ T-Cell Tolerance in the Liver2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inhibitory Effect of a Human MicroRNA, miR-6133-5p, on the Fibrotic Activity of Hepatic Stellate Cells in Culture2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] B型肝炎診療の現在 B型肝炎に対する新規薬剤の開発状況2020

Author(s)

Journal Title

Data Source

[Presentation] Functional cure を目指した OX40 刺激による HBV 特異的 CD8+T 細胞の賦活化2021

Author(s)

Organizer

Data Source

[Presentation] Suppression of intrahepatic hepatitis B surface antigen (HBsAg) prevents interferon mediated liver injury2020

Author(s)

Organizer

Data Source

[Presentation] CD8+T細胞のOX40シグナル刺激による持続的なHBs抗原抑制2020

Author(s)

Organizer

Data Source

kawashima keigo 河島圭吾

河島圭吾カワシマケイゴ

[Journal Article] B型肝炎診療の現在　B型肝炎に対する新規薬剤の開発状況2020