Nagaya Satomi 長屋聡美

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NAGAYA Satomi 長屋聡美

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Researcher Number	00882309
Other IDs
Affiliation (Current)	2025: 金沢大学, 保健学系, 助教
Affiliation (based on the past Project Information) *help	2020 – 2024: 金沢大学, 保健学系, 助教
Review Section/Research Field	Principal Investigator Basic Section 52010:General internal medicine-related / 0902:General internal medicine and related fields
Keywords	Principal Investigator 異常トロンビン / 血栓症 / トロンボモジュリン抵抗性 / アンチトロンビン抵抗性 / 血栓傾向 / 異常プロトロンビン / 血栓形成メカニズム / PAR-1 / トロンボモジュリン / トロンボモジュリン結合障害 / プロトロンビン / 血栓形成

Analysis of the mechanism of thrombogenesis mediated by thrombomodulin or PAR-1 of abnormal thrombinPrincipal Investigator
- Principal Investigator
  
  長屋聡美
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Kanazawa University
Molecular biological analysis of the mechanism of thrombus formation by impaired thrombomodulin binding of abnormal prothrombinPrincipal Investigator
- Principal Investigator
  
  NAGAYA Satomi
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Kanazawa University
Elucidation of the pathogenesis of thrombosis caused by abnormal prothrombin with thrombomodulin resistancePrincipal Investigator
- Principal Investigator
  
  NAGAYA Satomi
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0902:General internal medicine and related fields
- Research Institution
  Kanazawa University

All 2024 2023 2022 2021 2020

All Journal Article Presentation Book

[Book] モデル動物の作製と利用－循環器疾患2021 上巻：DICモデル2021
- Author(s)
  長屋聡美、森下英理子
- Total Pages
  7
- Publisher
  株式会社エル・アイ・シー
- ISBN
  9784900487581
- Data Source
  KAKENHI-PROJECT-20K22869
[Journal Article] Identification of two de novo variants causing inherited antithrombin deficiency by quantitative analysis of variant alleles2024
- Author(s)
  Togashi Tomoki、Nagaya Satomi、Meguro-Horike Makiko、Matsumoto Haruto、Imai Yuta、Yamaguchi Koichi、Fujii Yoshinari、Moriya Haruka、Kikuchi Yuika、Yasuda Ibuki、Horike Shin-ichi、Morishita Eriko
- Journal Title
  
  Thrombosis Research
  
  Volume: 233 Pages: 37-40
- DOI
  10.1016/j.thromres.2023.11.016
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06896, KAKENHI-PROJECT-22K07391, KAKENHI-PROJECT-22K15663
[Journal Article] Protein S deficiency caused by cryptic splicing due to the novel intron variant c.346+5G>C in PROS12023
- Author(s)
  Nagaya Satomi、Togashi Tomoki、Akiyama Masaharu、Imai Yuta、Matsumoto Haruto、Moriya Haruka、Meguro-Horike Makiko、Yasuda Ibuki、Kikuchi Yuika、Kuwajima Yamato、Horike Shin-ichi、Watanabe Atsushi、Morishita Eriko
- Journal Title
  
  Thrombosis Research
  
  Volume: 229 Pages: 26-30
- DOI
  10.1016/j.thromres.2023.06.020
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06896, KAKENHI-PROJECT-22K07391, KAKENHI-PROJECT-22K15663
[Journal Article] Functional analysis of two abnormal antithrombin proteins with different intracellular kinetics2023
- Author(s)
  Imai Yuta、Nagaya Satomi、Araiso Yuhei、Meguro-Horike Makiko、Togashi Tomoki、Horike Shin-ichi、Kawasaki Hiroshi、Morishita Eriko
- Journal Title
  
  Thrombosis Research
  
  Volume: 230 Pages: 18-26
- DOI
  10.1016/j.thromres.2023.08.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06896, KAKENHI-PROJECT-22K07391, KAKENHI-PROJECT-21K19306, KAKENHI-PROJECT-22K15663, KAKENHI-PROJECT-20H03338
[Journal Article] A case of venous thromboembolism caused by protein C deficiency due to a novel gene mutation2022
- Author(s)
  Noiri Jun-ichi、Matsuzoe Hiroki、Nagaya Satomi、Nishio Ryo、Matsumoto Daisuke、Takaishi Hiroshi、Morishita Eriko
- Journal Title
  
  Journal of Cardiology Cases
  
  Volume: 26 Issue: 5 Pages: 360-363
- DOI
  10.1016/j.jccase.2022.07.012
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07391, KAKENHI-PROJECT-22K15663
[Journal Article] Effect on Plasma Protein S Activity in Patients Receiving the Factor Xa Inhibitors2022
- Author(s)
  Nagaya S, Terakami T, Hayashi K,Furusho H, Fujino N, Kato T, Asakura H, Morishita E
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 29 Issue: 7 Pages: 1059-1068
- DOI
  10.5551/jat.62951
- NAID
  130008069021
- ISSN
  1340-3478, 1880-3873
- Year and Date
  2022-07-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K22869, KAKENHI-PROJECT-20H03927, KAKENHI-PROJECT-22K07391, KAKENHI-PROJECT-22K09136
[Journal Article] Identification and functional analysis of three novel genetic variants resulting in premature termination codons in three unrelated patients with hereditary antithrombin deficiency2022
- Author(s)
  Imai Yuta、Nagaya Satomi、Araiso Yuhei、Meguro-Horike Makiko、Togashi Tomoki、Ohmori Kensho、Makita Yuka、Sato Eiichi、Yujiri Toshiaki、Nagamori Yuta、Horike Shin-ichi、Watanabe Atsushi、Morishita Eriko
- Journal Title
  
  International Journal of Hematology
  
  Volume: 117 Issue: 4 Pages: 523-529
- DOI
  10.1007/s12185-022-03509-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07391, KAKENHI-PROJECT-22K15663
[Journal Article] First report of inherited protein S deficiency caused by paternal <I>PROS1</I> mosaicism2021
- Author(s)
  Nagaya Satomi、Maruyama Keiko、Watanabe Atsushi、Meguro-Horike Makiko、Imai Yuta、Hiroshima Yuki、Horike Shin-Ichi、Kokame Koichi、Morishita Eriko
- Journal Title
  
  Haematologica
  
  Volume: 107 Issue: 1 Pages: 330-333
- DOI
  10.3324/haematol.2021.278527
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07365, KAKENHI-PROJECT-20K22869, KAKENHI-PROJECT-20K07307, KAKENHI-PROJECT-20K16568
[Journal Article] Protein C Gene Mutation in an Older Adult Patient with Clostridium perfringens Septicemia-Related Visceral Vein Thrombosis2021
- Author(s)
  Kanosue K, Nagaya S, Morishita E, Yamanishi M, Imashuku S
- Journal Title
  
  TH open
  
  Volume: 5 Issue: 02 Pages: 171-173
- DOI
  10.1055/s-0041-1728664
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K22869
[Journal Article] Evaluation of Optimal Sample Processing Conditions for Accurate Measurement of Protein S Activity2021
- Author(s)
  Nagaya S, Araiso Y, Yamaguchi K, Omote Y, Matsui A, Asakura H, Morishita E
- Journal Title
  
  Annals of Clinical & Laboratory Science
  
  Volume: 51 Pages: 206-212
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K22869
[Journal Article] Evaluation of Optimal Sample Processing Conditions for Accurate Measurement of Protein S Activity.2021
- Author(s)
  Nagaya S, Araiso Y, Yamaguchi K, Omote Y, Matsui A, Asakura H, Morishita E
- Journal Title
  
  Ann Clin Lab Sci
  
  Volume: 51 Pages: 3-9
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K22869
[Journal Article] A Case of Treatment With Dabigatran for Cerebral Venous Thrombosis Caused by Hereditary Protein C Deficiency2021
- Author(s)
  Fukushima T, Shimomura Y, Nagaya S, Morishita E, Kawakami O
- Journal Title
  
  Cureus
  
  Volume: 13
- DOI
  10.7759/cureus.15473
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K22869
[Presentation] 出血傾向を呈する異常プロトロンビンSegoviaの機能解析2023
- Author(s)
  桑島大和, 長屋聡美, 今井湧太, 松本陽斗, 森屋羽瑠雅, 菊池結香, 安田芽生, 竹川清太郎, 築田怜奈, 西野優那, 油井陸斗, 神窪勇一, 森下英理子
- Organizer
  第47回北陸臨床病理集談会
- Data Source
  KAKENHI-PROJECT-22K15663
[Presentation] 遺伝性プロテインC欠乏症患者に同定された新規バリアントc.302G>T , p.Cys101Pheの症例報告2023
- Author(s)
  油井陸斗, 安田芽生, 長屋聡美, 今井湧太, 松本陽斗, 菊池結香, 森屋羽瑠雅, 桑島大和, 竹川清太郎, 築田怜奈, 西野優那, 目黒牧子, 堀家慎一, 森下英理子
- Organizer
  第47回北陸臨床病理集談会
- Data Source
  KAKENHI-PROJECT-22K15663
[Presentation] 遺伝性アンチトロンビン欠乏症2症例に同定された新規遺伝子バリアント2023
- Author(s)
  松本陽斗, 長屋聡美, 目黒牧子, 今井湧太, 竹川清太郎, 築田怜奈, 西野優那, 冨樫朋貴, 大森健聖, 牧田友香, 森屋羽瑠雅, 奥野隆祐, 堀家慎一, 森下英理子
- Organizer
  第45回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-22K15663
[Presentation] Prothrombin Himiのアンチトロンビン抵抗性および活性化プロテインC経路障害の解明2023
- Author(s)
  竹川清太郎,長屋聡美, 桑島大和, 今井湧太, 松本陽斗, 森屋羽瑠雅, 菊池結香, 安田芽生, 築田怜奈, 西野優那, 油井陸斗, 高村禅, 森下英理子
- Organizer
  第47回北陸臨床病理集談会
- Data Source
  KAKENHI-PROJECT-22K15663
[Presentation] コンピューター解析によって解明された血栓形成傾向に重要なプロテインC構造特性2023
- Author(s)
  安田芽生, Lopes Tiago J.S., Ferreira Marcos V., Alencar Brenno M., Rios Ricardo A., Rios Tatiane N., 長屋聡美, 森下英理子
- Organizer
  第85回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-22K15663
[Presentation] 先天性アンチトロンビン欠乏症患者に同定された新規バリアントp. Tyr395Asnの分子病態解析2023
- Author(s)
  築田怜奈, 長屋聡美, 松本陽斗, 今井湧太, 菊池結香, 安田芽生, 森屋羽瑠雅, 桑島大和, 竹川清太郎, 西野優那, 油井陸斗, 目黒牧子, 堀家慎一, 荒磯裕平, 森下英理子
- Organizer
  第47回北陸臨床病理集談会
- Data Source
  KAKENHI-PROJECT-22K15663
[Presentation] 出血傾向を呈する異常プロトロンビンSegoviaの機能解析2023
- Author(s)
  桑島大和, 長屋聡美, 大森健聖, 今井湧太, 冨樫朋貴, 牧田友香, 松本陽斗, 森屋羽瑠雅, 安田芽生, 菊池結香, 神窪勇一, 森下英理子
- Organizer
  第45回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-22K15663
[Presentation] プロテインC遺伝子における新規バリアントp.Leu173Proおよびp.Val241Leuの細胞内動態の解析2023
- Author(s)
  安田芽生, 長屋聡美, 大森健聖, 冨樫朋貴, 今井湧太, 森屋羽瑠雅, 菊池結香, 牧田友香, 松本陽斗, 目黒牧子, 三浦晃子, 堀家慎一, 森下英理子
- Organizer
  第45回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-22K15663
[Presentation] 新規に同定されたI型遺伝性アンチトロンビン欠乏症p.Cys32Trpの細胞内動態解析2023
- Author(s)
  菊池結香, 牧田友香, 長屋聡美, 今井湧太, 冨樫朋貴, 大森健聖, 安田芽生, 松本陽斗, 森屋羽瑠雅, 目黒牧子, 堀家慎一, 森下英理子
- Organizer
  第45回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-22K15663
[Presentation] 新規バリアントp.Cys64*を有する遺伝性プロテインC欠乏症の一例2023
- Author(s)
  安田芽生, 油井陸斗, 長屋聡美, 今井湧太, 松本陽斗, 菊池結香, 森屋羽瑠雅, 桑島大和, 竹川清太郎, 築田怜奈, 西野優那, 目黒牧子, 堀家慎一, 森下英理子
- Organizer
  第47回北陸臨床病理集談会
- Data Source
  KAKENHI-PROJECT-22K15663
[Presentation] 細菌感染症に伴うDICにおけるPS切断による抗凝固能低下の可能性2023
- Author(s)
  長屋聡美, 山口孝一, 松井杏沙佳, 津田友秀, 森下英理子
- Organizer
  第24回日本検査血液学会学術集会
- Data Source
  KAKENHI-PROJECT-22K15663
[Presentation] The potential of PS cleavage to regulate anticoagulant function in septic DIC2022
- Author(s)
  Satomi Nagaya, Koichi Yamaguchi, Asaka Matsui, Tomohide Tsuda, Eriko Morishita
- Organizer
  The 17th Cngress of Asian Society for Clinical Pathology and Laboratory Medicine
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K15663
[Presentation] Molecular characterization of a novel splicing mutation of the PROS1 gene causing inherited protein S deficiency2022
- Author(s)
  Tomoki Togashi, Satomi Nagaya, Makiko Meguro-Horike, Yuta Imai, Yuka Makita, Kensho Omori, Shin-Ichi Horike, Eriko Morishita
- Organizer
  The 17th Cngress of Asian Society for Clinical Pathology and Laboratory Medicine
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K15663
[Presentation] 新規スプライシング異常に起因した遺伝性プロテインS欠乏症患者の病態解析2022
- Author(s)
  長屋聡美, 冨樫朋貴, 今井湧太, 大森健聖, 牧田友香, 秋山政晴, 目黒牧子, 堀家慎一, 渡邉淳, 森下英理子
- Organizer
  第44回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-22K15663
[Presentation] Effects of sample processing on antithrombin and protein C activity2022
- Author(s)
  Satomi Nagaya, Koichi Yamaguchi, Eriko Morishita
- Organizer
  International Society for Laboratory Hematology 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K15663
[Presentation] The effect of the factor Xa inhibitors on plasma protein S activity2022
- Author(s)
  Takako Terakami, Satomi Nagaya, Yusuke Nakade, Hiroyasu Oe, Megumi Oshima, Mika Mori, Yoshio Saka, Toshihumi Gabata, Eriko Morishita
- Organizer
  The 17th Cngress of Asian Society for Clinical Pathology and Laboratory Medicine
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K15663
[Presentation] COVID-19関連凝固異常2021
- Author(s)
  長屋聡美、木村英晴、堀内久徳、浦野哲盟、森下英理子
- Organizer
  第16回日本血栓止血学会学術集会標準化委員会シンポジウム
- Data Source
  KAKENHI-PROJECT-20K22869
[Presentation] 父性モザイク遺伝性プロテインS欠乏症の1家系2021
- Author(s)
  長屋聡美、丸山慶子、渡邉淳、目黒牧子、廣島由紀、堀家慎一、小亀浩市、朝倉英策、森下英理子
- Organizer
  第39回日本血液学会北陸地方会
- Data Source
  KAKENHI-PROJECT-20K22869
[Presentation] プロテインS活性測定に影響する要因の検討2020
- Author(s)
  長屋聡美, 山口孝一, 冨樫朋貴, 荒磯裕平, 森広太朗, 花村美帆, 今井裕太, 關谷暁子, 朝倉英策, 森下英理子
- Organizer
  第21回日本検査血液学会学術集会
- Data Source
  KAKENHI-PROJECT-20K22869
[Presentation] 先天性プロテインS欠乏症およびプロテインS活性測定に影響する要因の検討2020
- Author(s)
  長屋聡美, 森下英理子
- Organizer
  第42回日本血栓止血学会学術集会臨床検査シンポジウム
- Data Source
  KAKENHI-PROJECT-20K22869

1. HORIKE Shinichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
2. 森下英理子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
3. 荒磯裕平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nagaya Satomi 長屋 聡美

NAGAYA Satomi 長屋 聡美

Research Projects

Research Products

Co-Researchers

Analysis of the mechanism of thrombogenesis mediated by thrombomodulin or PAR-1 of abnormal thrombinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular biological analysis of the mechanism of thrombus formation by impaired thrombomodulin binding of abnormal prothrombinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the pathogenesis of thrombosis caused by abnormal prothrombin with thrombomodulin resistancePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] モデル動物の作製と利用－循環器疾患2021 上巻：DICモデル2021

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Journal Article] Identification of two de novo variants causing inherited antithrombin deficiency by quantitative analysis of variant alleles2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Protein S deficiency caused by cryptic splicing due to the novel intron variant c.346+5G&gt;C in PROS12023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Functional analysis of two abnormal antithrombin proteins with different intracellular kinetics2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A case of venous thromboembolism caused by protein C deficiency due to a novel gene mutation2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effect on Plasma Protein S Activity in Patients Receiving the Factor Xa Inhibitors2022

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] Identification and functional analysis of three novel genetic variants resulting in premature termination codons in three unrelated patients with hereditary antithrombin deficiency2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] First report of inherited protein S deficiency caused by paternal &lt;I&gt;PROS1&lt;/I&gt; mosaicism2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Protein C Gene Mutation in an Older Adult Patient with Clostridium perfringens Septicemia-Related Visceral Vein Thrombosis2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Evaluation of Optimal Sample Processing Conditions for Accurate Measurement of Protein S Activity2021

Author(s)

Journal Title

Data Source

[Journal Article] Evaluation of Optimal Sample Processing Conditions for Accurate Measurement of Protein S Activity.2021

Author(s)

Journal Title

Nagaya Satomi 長屋聡美

NAGAYA Satomi 長屋聡美

[Journal Article] Protein S deficiency caused by cryptic splicing due to the novel intron variant c.346+5G>C in PROS12023

[Journal Article] First report of inherited protein S deficiency caused by paternal <I>PROS1</I> mosaicism2021