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Lee Yongchan  李 勇燦

ORCIDConnect your ORCID iD *help
Researcher Number 00894932
Other IDs
Affiliation (Current) 2025: 横浜市立大学, 生命医科学研究科, 助教
2025: 横浜市立大学, 理学部, 助教
Affiliation (based on the past Project Information) *help 2021 – 2024: 横浜市立大学, 生命医科学研究科, 助教
Review Section/Research Field
Principal Investigator
Basic Section 43020:Structural biochemistry-related
Except Principal Investigator
Transformative Research Areas, Section (II) / Basic Section 43030:Functional biochemistry-related
Keywords
Principal Investigator
構造解析 / 阻害剤 / Cryo-EM / 輸送体 / 尿酸 / 生体膜 / ナノディスク / クライオ電子顕微鏡 / アミノ酸輸送体
Except Principal Investigator
構造生物学 … More / クライオ電子顕微鏡 / 輸送体 / 膜タンパク質 / mass spectrometry / amino acid / exchanger / homeostasis / HATs / structure / kidney / transporter / amino acids / cystinuria Less
  • Research Projects

    (4 results)
  • Research Products

    (9 results)
  • Co-Researchers

    (2 People)
  •  Elucidating structural basis of substrate recognition by urate transportersPrincipal Investigator

    • Principal Investigator
      李 勇燦
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 43020:Structural biochemistry-related
    • Research Institution
      Yokohama City University
  •  クライオ電子顕微鏡による膜輸送タンパク質の動的構造解析と機能制御

    • Principal Investigator
      西澤 知宏
    • Project Period (FY)
      2024 – 2028
    • Research Category
      Grant-in-Aid for Transformative Research Areas (A)
    • Review Section
      Transformative Research Areas, Section (II)
    • Research Institution
      Yokohama City University
  •  Molecular mechanism of amino acid harmonization: a paradigm of heterodimeric amino acid transporters

    • Principal Investigator
      Wiriyasermkul Pattama
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 43030:Functional biochemistry-related
    • Research Institution
      Iwate University
      Jikei University School of Medicine
  •  Structural and functional elucidation of L-type amino acid transporter under lipid environmentPrincipal Investigator

    • Principal Investigator
      Lee Yongchan
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 43020:Structural biochemistry-related
    • Research Institution
      Yokohama City University

All 2023 2022 2021

All Journal Article Presentation

  • [Journal Article] Structural basis of anticancer drug recognition and amino acid transport by LAT12023

    • Author(s)
      Lee Yongchan、Jin Chunhuan、Ohgaki Ryuichi、Xu Minhui、Ogasawara Satoshi、Warshamanage Rangana、Yamashita Keitaro、Murshudov Garib、Nureki Osamu、Murata Takeshi、Kanai Yoshikatsu
    • Journal Title

      bioRxiv

      Volume: -

    • DOI

      10.1101/2023.12.03.567112

    • Open Access
    • Data Source
      KAKENHI-PROJECT-21K15031
  • [Journal Article] Ca2+-mediated higher-order assembly of b0,+AT-rBAT is a key step for system b0,+ biogenesis and cystinuria2021

    • Author(s)
      Lee Yongchan、Wiriyasermkul Pattama、Moriyama Satomi、Mills Deryck J.、Kuehlbrandt Werner、Nagamori Shushi
    • Journal Title

      bioRxiv

      Volume: -

    • DOI

      10.1101/2021.05.06.443019

    • Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K15031
  • [Presentation] クライオ電子顕微鏡によるアミノ酸輸送体の構造薬学的研究2023

    • Author(s)
      李勇燦
    • Organizer
      日本顕微鏡学会 第66回シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K15031
  • [Presentation] 哺乳類が持つヘテロ複合体型アミノ酸輸送体の構造解析2023

    • Author(s)
      李勇燦
    • Organizer
      第23回日本蛋白質科学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K15031
  • [Presentation] Structural studies of SLC amino acid transporters relevant to health and diseases2023

    • Author(s)
      Yongchan Lee
    • Organizer
      International Conference on Biological Physics (ICBP2023)
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K15031
  • [Presentation] Structural Studies of Membrane Transporters Relevant to Health and Diseases2022

    • Author(s)
      Yongchan Lee
    • Organizer
      2022 China-Japan-Korea Youth Forum
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K15031
  • [Presentation] Cryo-EM Structure of L-type Amino Acid Transporter 2 (LAT2)2022

    • Author(s)
      Saki Takahashi, Yongchan Lee, Satoshi Ogasawara, Takeshi Murata, Yoshikatsu Kanai, Tomohiro Nishizawa
    • Organizer
      第45回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-21K15031
  • [Presentation] 脂質二重膜に埋め込まれた膜タンパク質のCryo-EM構造解析2021

    • Author(s)
      李 勇燦
    • Organizer
      第44回 日本分子生物学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K15031
  • [Presentation] Structural mechanisms of heteromeric amino acid transporters revealed by cryo-EM and insights into cystinuria2021

    • Author(s)
      Yongchan Lee
    • Organizer
      第94回 日本生化学会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K15031
  • 1.  Wiriyasermkul Pattama (80825836)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  西澤 知宏 (80599077)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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