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Tamemoto Yuta  爲本 雄太

ORCIDConnect your ORCID iD *help
Researcher Number 00982159
Other IDs
Affiliation (Current) 2026: 千葉大学, 大学院薬学研究院, 助教
Affiliation (based on the past Project Information) *help 2023 – 2025: 千葉大学, 大学院薬学研究院, 助教
Review Section/Research Field
Principal Investigator
Basic Section 47060:Clinical pharmacy-related / 0801:Pharmaceutical sciences and related fields
Keywords
Principal Investigator
ドラッグデリバリーシステム / 腹腔内投与 / 腹膜播種 / プロテインコロナ / 脂質ナノ粒子 / 生理学的薬物速度論 / タンパク結合 / 2次元電気泳動 / LC-MS/MS / 低分子化合物
  • Research Projects

    (2 results)
  • Research Products

    (16 results)
  •  脂質ナノ粒子の腹水プロテインコロナの網羅的解析と腹膜播種への送達最適化Principal Investigator

    • Principal Investigator
      爲本 雄太
    • Project Period (FY)
      2025 – 2026
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 47060:Clinical pharmacy-related
    • Research Institution
      Chiba University
  •  Establishment of a peritoneal dissemination treatment strategy based on the prediction of the pharmacokinetic mechanism of small molecule anticancer agents after intraperitoneal administrationPrincipal Investigator

    • Principal Investigator
      Tamemoto Yuta
    • Project Period (FY)
      2023 – 2024
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Review Section
      0801:Pharmaceutical sciences and related fields
    • Research Institution
      Chiba University

All 2025 2024 2023

All Journal Article Presentation

  • [Journal Article] Buffer compositions strongly impact the in vitro assessment of CYP fraction metabolized using human liver microsomes or expressed isoenzymes2025

    • Author(s)
      Tamemoto Yuta、Shibata Yukihiro、Hashimoto Natsumi、Yoshitomo Aoi、Hozuki Shizuka、Takahashi Keita、Kumemura Hana、Hatakeyama Hiroto、Sato Hiromi、Hisaka Akihiro
    • Journal Title

      Drug Metabolism and Pharmacokinetics

      Volume: in press Pages: 101480-101480

    • DOI

      10.1016/j.dmpk.2025.101480

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K19422
  • [Presentation] マウス大腸癌腹膜播種モデルを用いた腹腔内投与後の低分子化合物の体内動態解析2025

    • Author(s)
      石田 深紗紀, 爲本 雄太, 畠山 浩人
    • Organizer
      日本薬学会第145年会
    • Data Source
      KAKENHI-PROJECT-23K19422
  • [Presentation] ヒト/マウスがん細胞における脂質ナノ粒子の細胞内動態の系統的評価2025

    • Author(s)
      大野浩暉, 爲本雄太, 張崇傑, 千野友太郎, 田中莉奈, 劉怡, 千田克幸, 佐藤悠介, 畠山浩人
    • Organizer
      日本薬学会第145年会
    • Data Source
      KAKENHI-PROJECT-23K19422
  • [Presentation] Elucidation of the mechanism of glycosylation-mediated antibody production for rapid adjuvant-free vaccine development.2025

    • Author(s)
      Ruiheng Tang, Riho Kume, Kazuto Yasuda, Yuta Tamemoto, Hiroto Hatakeyama
    • Organizer
      The 11th global network forum on infection and Immunity: Synergistic Innovation of Microbiology, Mucosal Immunology and Vaccinology.
    • Data Source
      KAKENHI-PROJECT-23K19422
  • [Presentation] 腹腔内投与後の脂質ナノ粒子の腹膜播種への送達と分布メカニズムに関する検討2025

    • Author(s)
      張崇傑, 松本唯, 千野友太郎, 爲本雄太, 畠山浩人
    • Organizer
      日本薬学会第145年会
    • Data Source
      KAKENHI-PROJECT-23K19422
  • [Presentation] 抗PD-L1抗体ががん関連骨髄系細胞によるアナフィラキシーの発症を増悪するメカニズムの解明2025

    • Author(s)
      唐 鋭恒, 久米 里歩, 安田 一翔, 爲本 雄太, 東 恭平, 畠山 浩人
    • Organizer
      日本薬学会第145年会
    • Data Source
      KAKENHI-PROJECT-23K19422
  • [Presentation] Evaluation of distribution mechanisms of lipid nanoparticles to peritoneal dissemination via i.p. administration.2024

    • Author(s)
      Chongjie Zhang, Yui Matsumoto, Yutaro Chino, Yuta Tamemoto, Hidetaka Akita, Hiroto Hatakeyama
    • Organizer
      第40回日本DDS学会学術集会
    • Data Source
      KAKENHI-PROJECT-23K19422
  • [Presentation] 免疫チェックポイント阻害剤のFc受容体親和性が腹膜播種モデルの腹腔内動態に与える影響の解析.2024

    • Author(s)
      畠山浩人, 釣谷美遥, 唐鋭恒, 津田涼太, 山本麻由, 爲本雄太
    • Organizer
      日本薬剤学会第39年会
    • Data Source
      KAKENHI-PROJECT-23K19422
  • [Presentation] 脂質ナノ粒子の腹腔内投与後の腹膜播種への移行と機能評価2024

    • Author(s)
      畠山浩人, 張崇傑, 松本唯, 田中莉奈, 劉怡, 千野友太郎, 大野浩暉, 爲本雄太
    • Organizer
      第45回生体膜と薬物の相互作用シンポジウム
    • Data Source
      KAKENHI-PROJECT-23K19422
  • [Presentation] ヒト代謝酵素CYP3Aを介する多様な相互作用を1つの基質結合部位で説明するモデル解析2024

    • Author(s)
      爲本 雄太, 橋本 なつみ, 久米村 花菜, 高橋 慶多, 佐藤 洋美, 樋坂 章博
    • Organizer
      第18回次世代を担う若手のための医療薬科学シンポジウム
    • Data Source
      KAKENHI-PROJECT-23K19422
  • [Presentation] Clinical science for drug post-marketing of small molecule drugs and antibody therapeutics based on medical big data analysis.2023

    • Author(s)
      Yuta Tamemoto.
    • Organizer
      Asia Symposium on Pharmaceutical Sciences for the Next Generation: Clinical Research in the 144th Annual Meeting of the PSJ
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K19422
  • [Presentation] A new approach to evaluate in vivo inhibition ratio of CYP3A based on data from adverse event reporting system without using pharmacokinetic information.2023

    • Author(s)
      Hana Kumemura, Yuta Tamemoto, Shizuka Hozuki, Hiromi Sato, Akihiro Hisaka.
    • Organizer
      2023 ICCP450/JSSX
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K19422
  • [Presentation] Significance of choice of substrate drugs and buffer conditions which affect the assessment of in vitro inhibition of metabolism by CYP3A.2023

    • Author(s)
      Natsumi Hashimoto, Yuta Tamemoto, Keita Takahashi, Hana Kumemura, Hiromi Sato, Akihiro Hisaka.
    • Organizer
      2023 ICCP450/JSSX
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K19422
  • [Presentation] 抗PD-L1抗体のクローンの違いがアナフィラキシーに及ぼす影響の解析.2023

    • Author(s)
      唐鋭恒, 久米里歩, 荒井貴宏, 宮島倫, 真中瞳, 小久保朋美, 爲本雄太, 東恭平, 畠山浩人.
    • Organizer
      日本薬学会第144年会
    • Data Source
      KAKENHI-PROJECT-23K19422
  • [Presentation] 非定型的なCYP3Aの代謝反応を1つの基質結合部位で網羅的に説明する新しいモデル:ビッグサイトモデル.2023

    • Author(s)
      爲本雄太, 橋本なつみ, 久米村花菜, 高橋慶多, 佐藤洋美, 樋坂章博.
    • Organizer
      日本薬学会第144年会
    • Data Source
      KAKENHI-PROJECT-23K19422
  • [Presentation] Investigation of delivery of immune checkpoint inhibitors after i.p. administration to peritoneal metastasis via direct penetration: Effect on differences in type of cancers.2023

    • Author(s)
      Ryota Tsuda, Mayu Yamamoto, Yui Matsumoto, Chongjie Zhang, Yuta Tamemoto, Hiroto Hatakeyama.
    • Organizer
      2023 ICCP450/JSSX
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K19422

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