FUKAI Toshio 深井俊夫

Researcher Number	10057755
Affiliation (based on the past Project Information) *help	2011 – 2016: 横浜薬科大学, 薬学部, 教授 1987 – 1988: 東邦大学, 薬学部, 助教授
Review Section/Research Field	Principal Investigator Medical systems / Medical systems Except Principal Investigator Chemical pharmacy
Keywords	Principal Investigator 音響化学療法 / 超音波 / 活性酸素種 / 一重項酸素 / アポトーシス / 活性酸素 / カーボンナノチューブ / 音響化学的 / 水酸化カーボンナノチューブ / 機能性カーボンナノチューブ … More Except Principal Investigator … More Cinnamoylpolyketide / Kuwanon J / Chalcomoracin / Diels-Alder type adduct / Cell culture / Biosynthesis / Morus alba / α-アリルベンゾフラン / Diels-Alder型付加体 / カルコン / 2-アリルベンゾフラン / シンナモイルポリケチド / クワノンJ / カルコモラシン / Diels-Alder型付加化合物 / 生合成 / クワカルス Less

Development of Novel Antitumor Treatment by Sonodynamically Activated Hydroxyl Functionalized Carbon NanotubesPrincipal Investigator
- Principal Investigator
  
  FUKAI TOSHIO
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical systems
- Research Institution
  Yokohama College of Pharmacy
Study on selective cancer therapy using apoptosis induced by sonodynamically activated drugPrincipal Investigator
- Principal Investigator
  
  FUKAI Toshio
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical systems
- Research Institution
  Yokohama College of Pharmacy
BIOSYNTHESIS OF DIELS-ALDER TYPE ADDUCTS IN MORUS ALBA L. CELL CULTURES
- Principal Investigator
  
  NOMURA Taro
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  TOHO UNIVERSITY

All 2016 2015 2013 2012 2011 Other

All Journal Article Presentation

[Journal Article] Antitumor effect of sonodynamically activated pyrrolidine tris-acid fullerene2016
- Author(s)
  Yumiko Iwase, Koji Nishi, Junya Fujimori, Toshio Fukai, Nagahiko Yumita, Toshihiko Ikeda, Fu-shin Chen, Yasunori Momose and Shin-ichiro Umemura
- Journal Title
  
  Jpn. J. Appl. Phys.
  
  Volume: 55
- NAID
  210000146827
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26350550
[Journal Article] Antitumor effect of sonodynamically activated pyrrolidine tris-acid fullerene2015
- Author(s)
  Yumiko Iwase, Koji Nishi, Junya Fujimori, Toshio Fukai, Nagahiko Yumita, Toshihiko Ikeda, Fu-shin Chen, Yasunori Momose, Shin-ichiro Umemura
- Journal Title
  
  Japanese Journal of Applied Physics
  
  Volume: 54
- NAID
  210000146827
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26350550
[Journal Article] Apoptosis of HL-60 Cells Induced by Sonodynamic Therapy with Zinc Phthalocyanine Tetrasulfonate.2012
- Author(s)
  Yumita N, Iwase Y, Nishi K, Ikeda K, Onodera K, Fukai T, Umemura S, Momose Y.
- Journal Title
  
  Pharmacometrics
  
  Volume: 82 Pages: 75-83
- NAID
  10030927893
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500570
[Journal Article] Apoptosis of HL-60 Cells Induced by Sonodynamic Therapy with Zinc Phthalocyanine Tetrasulfonate2012
- Author(s)
  Yumita N, Iwase Y, Nishi K, Ikeda K, Onodera K, Fukai T, Umemura S, Momose Y
- Journal Title
  
  Pharmacometrics
  
  Volume: 82 Pages: 75-83
- NAID
  10030927893
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500570
[Journal Article] Involvement of Reactive Oxygen Species in Sonodynamically Induced Apoptosis Using a Novel Porphyrin Derivative2012
- Author(s)
  Nagahiko Yumita, Yumiko Iwase, Koji Nishi, Hajime Komatsu, Kazuyoshi Takeda, Kenji Onodera, Toshio Fukai, Toshihiko Ikeda, Shin-ichiro Umemura, Kazuho Okudaira, Yasunori Momose
- Journal Title
  
  Theranostics
  
  Volume: 2 Issue: 9 Pages: 880-888
- DOI
  10.7150/thno.3899
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500444, KAKENHI-PROJECT-23500569, KAKENHI-PROJECT-23500570
[Journal Article] Involvement of Reactive Oxygen Species in Sonodynamically Induced Apoptosis by 4-formyloximeetylidene-3-hydroxyl-2-vinyl-deut erio-Porphynyl (IX)-6-7-diaspartic acid (ATX-S10)2012
- Author(s)
  Yumita N, Iwase Y, Nishi K, Ikeda T, Fukai T, Onodera K, Takeda K, Umemura S, Okudaira K, Momose Y
- Journal Title
  
  Biochemistry & Analytical Biochemistry
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500570
[Journal Article] Involvement of Reactive Oxygen Species in Sonodynamically Induced Apoptosis by Novel Porphyrin Derivative2012
- Author(s)
  Yumita N, Iwase Y, Nishi K, Komatsu H, Fukai T, Ikeda T, Umemura S, Momose Y
- Journal Title
  
  Theranostics
  
  Volume: 2 Pages: 880-888
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500570
[Journal Article] Sonodynamic Antitumor Effect of Zinc Phthalocyanine Tetrasulfate on Murine Solid Tumor colon 262011
- Author(s)
  Yumita N, Iwase Y, Onodera K, Nishi H, Takeda K, Fukai, T, Umemura S, Okudaira K, Momose Y
- Journal Title
  
  Pharmacometrics
  
  Volume: 80 Pages: 13-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500570
[Journal Article] Sonodynamically-induced antitumor effect of mono-l-aspartyl chlorin e6 (NPe6)2011
- Author(s)
  Yumita N, Iwase Y, Nishi K, Ikeda T, Komatsu H, Fukai T, Onodera K, Nishi H, Takeda K, Umemura S, Okudaira K, Momose Y
- Journal Title
  
  Anticancer Res
  
  Volume: 31 Pages: 501-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500570
[Journal Article] Sonodynamically-induced antitumor effect of mono-l-aspartyl chlorin e6 (NPe6)2011
- Author(s)
  N. Yumita, Y. Iwase, K. Nishi, T. Ikeda, H. Komatsu, T. Fukai, K. Onodera, H. Nishi, K. Takeda, S. Umemura, K. Okudaira and Y. Momose
- Journal Title
  
  Anticancer Res.
  
  Volume: 31 Pages: 501-506
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500570
[Journal Article] Involvement of Reactive Oxygen Spe-cies in Sonodynami-cally Induced Apopto-sis by 4-formyloximeetylidene-3-hydroxyl-2-vinyl-deuterio-Porphynyl (IX)-6-7-diaspartic acid (ATX-S10)2011
- Author(s)
  N.Yumita, Y.Iwase, K.Nishi, T.Ikeda, T.Fukai, K.Takeda, K.Onodera, S.Umemura, K.Okudaira, Y.Momose
- Journal Title
  
  Biochemistry & Analytical Bio-chemistry
  
  Volume: S2 Issue: 02 Pages: 2-7
- DOI
  10.4172/2161-1009.s2-001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500444, KAKENHI-PROJECT-23500569, KAKENHI-PROJECT-23500570
[Journal Article] Sonodynamic An-titumor Effect of Zinc Phthalocyanine Tetrasulfate on Murine Solid Tumor Colon 262011
- Author(s)
  N. Yumita, Y. Iwase, K. Onodera, H. Nishi, K. Takeda, T. Fukai, S. Umemura, K. Okudaira and Y. Mo-mose
- Journal Title
  
  Pharmacometrics
  
  Volume: 80 Pages: 13-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500570
[Presentation] Sonodynamically Induced Apoptosis by 5-Aminolevulinic acid2016
- Author(s)
  Nagahiko Yumita, Yumiko Iwase, Koji Nishi, Takahiro Watanabe, Junya Fujimori, Toshio Fukai, Hiroyuki Kuwahara, Shin-ichiro Umemura
- Organizer
  International Conference on Porphyrins and Phthalocyanines (国際学会)
- Place of Presentation
  中国・南京
- Year and Date
  2016-07-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26350550
[Presentation] Antitumor effect of sonodynamically activated pyrrolidine tris-acid fullerene2015
- Author(s)
  Yumiko Iwase, Koji Nishi, Junya Fujimori, Toshio Fukai, Nagahiko Yumita, Toshihiko Ikeda, Fu-shin Chen, Yasunori Momose, Shin-ichiro Umemura
- Organizer
  第36回　超音波エレクトロニクスの基礎と応用に関するシンポジウム（USE2015）
- Place of Presentation
  つくば国際会館（エポカルつくば）
- Year and Date
  2015-11-05
- Data Source
  KAKENHI-PROJECT-26350550
[Presentation] Sonodynamically Induced Antitumor Effect of Novel Porphyrin Derivative2013
- Author(s)
  Nagahiko Yumita, Yumiko Iwase, Koji Nishi, Toshihiko Ikeda, Toshio Fukai, Shin-ichiro Umemura
- Organizer
  世界薬学会議（FIP2013）（第73回）
- Place of Presentation
  ダブリン
- Data Source
  KAKENHI-PROJECT-23500570
[Presentation] Involvement of Reactive Oxygen Species in Apoptosis Induced by Sonodynamic Therapy with Chloroaluminum Phthalocyanine Tetrasulfonate2013
- Author(s)
  Nagahiko Yumita, Saeko Nakamura, Yumiko Iwase, Toshio Fukai, Toshihiko Ikeda, Shin-ichro Umemura
- Organizer
  SFRBM's 20th Annual Meeting
- Place of Presentation
  サンアントニオ
- Data Source
  KAKENHI-PROJECT-23500570
[Presentation] Sonodynamically Induced Antitumor Effect of Novel Porphyrin Derivative2013
- Author(s)
  Nagahiko Yumita, Yumiko Iwase, Koji Nishi, Toshihiko Ikeda, Toshio Fukai, Shin-ichiro Umemura
- Organizer
  第73回世界薬学大会(FIP2013)
- Place of Presentation
  ダブリン
- Data Source
  KAKENHI-PROJECT-23500570
[Presentation] ATX-S10の音響化学的活性化によるアポトーシス誘導2012
- Author(s)
  弓田長彦, 岩瀬由未子, 深井俊夫, 武田収功, 小野寺憲治, 池田敏彦, 梅村晋一郎, 奥平和穂, 百瀬弥寿徳
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-23500570
[Presentation] Involvement of Reactive Oxygen Species in Sonodynamically Induced Antitumor Effect by Water-solve Functionalized Fullereneas
- Author(s)
  Nagahiko Yumita, Yumiko Iwase, Koji Nishi, Toshio Fukai, Toshihiko Ikeda, Fu-shih Chen, Yasunori Momose, Shin-ichiro Umemura
- Organizer
  Society for Free Radical Biology and Medicine’s 21th Annual Meeting（SFRBM 2014）
- Place of Presentation
  Seattle, WA. (Sheraton Seattle)
- Year and Date
  2014-11-19 – 2014-11-23
- Data Source
  KAKENHI-PROJECT-26350550

1. YUMITA Nagahiko (40191481)

# of Collaborated Projects: 2 results

# of Collaborated Products: 19 results
2. IWASE Yumiko (00521882)

# of Collaborated Projects: 2 results

# of Collaborated Products: 19 results
3. NOMURA Taro (90057505)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. TSUBURA Hiromi (80180040)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. HANO Yoshio (00156382)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 梅村晋一郎 (20402787)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results

FUKAI Toshio 深井 俊夫

Research Projects

Research Products

Co-Researchers

Development of Novel Antitumor Treatment by Sonodynamically Activated Hydroxyl Functionalized Carbon NanotubesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on selective cancer therapy using apoptosis induced by sonodynamically activated drugPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

BIOSYNTHESIS OF DIELS-ALDER TYPE ADDUCTS IN MORUS ALBA L. CELL CULTURES

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Antitumor effect of sonodynamically activated pyrrolidine tris-acid fullerene2016

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Antitumor effect of sonodynamically activated pyrrolidine tris-acid fullerene2015

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Apoptosis of HL-60 Cells Induced by Sonodynamic Therapy with Zinc Phthalocyanine Tetrasulfonate.2012

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Apoptosis of HL-60 Cells Induced by Sonodynamic Therapy with Zinc Phthalocyanine Tetrasulfonate2012

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Involvement of Reactive Oxygen Species in Sonodynamically Induced Apoptosis Using a Novel Porphyrin Derivative2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Involvement of Reactive Oxygen Species in Sonodynamically Induced Apoptosis by 4-formyloximeetylidene-3-hydroxyl-2-vinyl-deut erio-Porphynyl (IX)-6-7-diaspartic acid (ATX-S10)2012

Author(s)

Journal Title

Data Source

[Journal Article] Involvement of Reactive Oxygen Species in Sonodynamically Induced Apoptosis by Novel Porphyrin Derivative2012

Author(s)

Journal Title

Data Source

[Journal Article] Sonodynamic Antitumor Effect of Zinc Phthalocyanine Tetrasulfate on Murine Solid Tumor colon 262011

Author(s)

Journal Title

Data Source

[Journal Article] Sonodynamically-induced antitumor effect of mono-l-aspartyl chlorin e6 (NPe6)2011

Author(s)

Journal Title

Data Source

[Journal Article] Sonodynamically-induced antitumor effect of mono-l-aspartyl chlorin e6 (NPe6)2011

Author(s)

Journal Title

Data Source

[Journal Article] Involvement of Reactive Oxygen Spe-cies in Sonodynami-cally Induced Apopto-sis by 4-formyloximeetylidene-3-hydroxyl-2-vinyl-deuterio-Porphynyl (IX)-6-7-diaspartic acid (ATX-S10)2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Sonodynamic An-titumor Effect of Zinc Phthalocyanine Tetrasulfate on Murine Solid Tumor Colon 262011

Author(s)

Journal Title

Data Source

[Presentation] Sonodynamically Induced Apoptosis by 5-Aminolevulinic acid2016

Author(s)

Organizer

Place of Presentation

FUKAI Toshio 深井俊夫