HATAYAMA Takumi 畑山巧

… Alternative Names

畑山巧ハタヤマタクミ

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Researcher Number	10094484
Other IDs
Affiliation (based on the past Project Information) *help	2014: 京都薬科大学, 薬学部, 名誉教授 2001 – 2006: 京都薬科大学, 薬学部, 教授 1998 – 1999: 京都薬科大学, 教授 1997 – 1999: 京都薬科大学, 薬学部, 教授 1995: 京都薬科大学, 薬学部, 教授 … More 1993: 京都薬科大学, 薬学部, 助教授 1991: 京都薬科大学, 医学部, 助教授 1989 – 1990: 京都薬科大学, 薬学部, 助教授 1988: 京都薬科大学, 薬学部・第一生化学教室, 助教授 1987: 大阪市立大学, 医学部, 講師 Less
Review Section/Research Field	Principal Investigator Neurology / Neurology / General medical chemistry Except Principal Investigator General anatomy (including Histology/Embryology) / Biological pharmacy
Keywords	Principal Investigator Hsp105 / SBMA / Apoptosis / アポトーシス / 分子シャペロン / HSP105 / Polygultamine disease / Molecular chaperone / Hsp70 / ポリグルタミン病 … More / ストレス蛋白質 / NSAIDs / Hsp40 / 熱ショックタンパク質 / 熱ショック蛋白質 / Hsp-inducing drug / Hsp誘導剤 / 脳神経疾患 / HSP誘導剤 / Mouse / Heat shock protein / Embryo developement / HSP105 gene / Stress protein / マウス / 胎児発生 / HSP105遺伝子 / カゼインキナーゼII / リン酸化 / ストレスタンパク質 / FM3A細胞 / cDNAクローニング / 哺乳動物細胞 / hsp105 … More Except Principal Investigator 熱耐性 / 熱ショック蛋白質 / 温熱療法 / Folic acid / Neurulation / Central nervous system / Hox genes / Embryos / Developmental abnormalities / Hyperthermia / Physical agents / 先天異常 / 熱ショック蛋白 / 遺伝子発現 / 脳発生異常 / 形態形成 / トランスフォーメーション / 脊柱 / ニューロン / 胎児脳 / 熱ショック / 葉酸 / 神経管形成 / 中枢神経系 / Hox遺伝子 / 胚子 / 発生異常 / 高温 / 物理的要因 / MRスペクトロスコピー / Heat ShocR Protein / 熱感受性 / ハイパーサーミヤ / グルコース / 膜作用物質 / Heat Shock Protein / ポリグルタミン病 / ナリンゲニン / GRP78 / 伸長ポリグルタミン病 / 小胞体分子シャペロン / ＧＲＰ７８ / 小胞体ストレス / 神経変性疾患 / 温熱耐性 / ストレス蛋白質 / がん細胞 Less

Regulation of endoplasmic reticulum chaperone GRP78 expression in expanded polyglutamine diseases
- Principal Investigator
  
  YAMAGISHI Nobuyuki
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kyoto Pharmaceutical University
Studies on molecular mechanisms of polyglutamine diseases and its treatment with molecularPrincipal Investigator
- Principal Investigator
  
  HATAYAMA Takumi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kyoto Pharmaceutical University
Studies of polyQ diseases : possible mechanisms of cell death and its prevention by molecular chaperonePrincipal Investigator
- Principal Investigator
  
  HATAYAMA Takumi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kyoto Pharmaceutical University
Effects of molecular chaperones on polyQ-mediated cell death and toxicity using cellular model of SBMAPrincipal Investigator
- Principal Investigator
  
  HATAYAMA Takumi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kyoto Pharmaceutical University
高分子量ストレス蛋白質HSP105の機能解析Principal Investigator
- Principal Investigator
  
  畑山巧
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyoto Pharmaceutical University
Developmental Brain Disorders due to Physical Agents
- Principal Investigator
  
  SHIOTA Kohei
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  KYOTO UNIVERSITY
Roles of stress protein hsp105 during mouse embryo development.Principal Investigator
- Principal Investigator
  
  HATAYAMA Takumi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Kyoto Pharmaceutical University
高分子量ストレス蛋白質の構造と機能Principal Investigator
- Principal Investigator
  
  畑山巧
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto Pharmaceutical University
高分子量ストレス蛋白質の構造と機能Principal Investigator
- Principal Investigator
  
  畑山巧
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto Pharmaceutical University
癌細胞および正常細胞における熱ショック蛋白質発現機構とその修飾因子に関する研究
- Principal Investigator
  
  永田和宏
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyoto University
癌細胞および正常細胞における熱ショック蛋白質発現機構とその修飾因子に関する研究
- Principal Investigator
  
  永田和宏
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyoto University
癌細胞および正常細胞における熱ショック蛋白質発現機構とその修飾因子に関する研究
- Principal Investigator
  
  永田和宏
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyoto University
温熱耐性の発現機構の解明とその修飾に関する研究
- Principal Investigator
  
  田中敬正
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kansai Medical University
温熱耐性の発現機構の解明とその修飾に関する研究
- Principal Investigator
  
  田中敬正
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kansai Medical University

All 2012

All Journal Article Presentation

[Journal Article] Decreased expression of endoplasmic reticulum chaperone GRP78 in liver of diabetic mice2012
- Author(s)
  Nobuyuki Yamagishi, Takashi Ueda, Akinori Mori, Youhei Saito, Takumi Hatayama
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 417 Issue: 1 Pages: 364-370
- DOI
  10.1016/j.bbrc.2011.11.118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590094
[Journal Article] Naringenin Inhibits the Aggregation of Expanded Polyglutamine Tract-Containing Protein through the Induction of Endoplasmic Reticulum Chaperone GRP782012
- Author(s)
  Nobuyuki Yamagishi, Yoko Yamamoto, Chika Noda, Takumi Hatayama
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 35 Issue: 10 Pages: 1836-1840
- DOI
  10.1248/bpb.b12-00451
- NAID
  130001872378
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590094
[Journal Article] Endoplasmic reticulum chaperone GRP78 suppresses the aggregation of proteins containing expanded polyglutamine tract2012
- Author(s)
  Nobuyuki Yamagishi, Shoichi Magara, Satoko Tamura, Youhei Saito, Takumi Hatayama
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 417 Issue: 3 Pages: 527-533
- DOI
  10.1016/j.bbrc.2012.05.078
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590094
[Presentation] ナリンゲニンによる小胞体分子シャペロンGRP78の発現誘導2012
- Author(s)
  ○ 山岸伸行、野田知加、山本洋子、斉藤洋平、畑山　巧
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590094
[Presentation] 漢方薬成分からの小胞体分子シャペロンGRP78誘導物質の検索2012
- Author(s)
  山本洋子、野田知加、山岸伸行、斉藤洋平、中山祐治、畑山　巧
- Organizer
  第62回日本薬学会近畿支部総会・大会
- Place of Presentation
  兵庫県西宮市
- Data Source
  KAKENHI-PROJECT-23590094

1. YAMAGISHI Nobuyuki (60298685)

# of Collaborated Projects: 6 results

# of Collaborated Products: 4 results
2. OHTSUKA Kenzo (40150213)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. 永田和宏 (50127114)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. 渡辺正己 (20111768)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. 平岡真寛 (70173218)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. 矢原一郎 (60109957)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. YASUDA Kunihiko (50278446)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. ISHIHARA Keiichi (80340446)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 若槻徹 (20121577)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 田中敬正 (40131445)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. 鈴木紀夫 (10010050)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. 坂本澄彦 (20014029)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. 安徳重敏 (40034623)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. SHIOTA Kohei (80109529)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. NARUSE Ichiro (20113326)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. SAITO Youhei (90411032)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 小山洋道 (00170407)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 李忠連 (80319532)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 滝川俊也 (90263095)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. MIURA Takashi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

HATAYAMA Takumi 畑山 巧

畑山 巧 ハタヤマ タクミ

Research Projects

Research Products

Co-Researchers

Regulation of endoplasmic reticulum chaperone GRP78 expression in expanded polyglutamine diseases

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on molecular mechanisms of polyglutamine diseases and its treatment with molecularPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies of polyQ diseases : possible mechanisms of cell death and its prevention by molecular chaperonePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effects of molecular chaperones on polyQ-mediated cell death and toxicity using cellular model of SBMAPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

高分子量ストレス蛋白質HSP105の機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Developmental Brain Disorders due to Physical Agents

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Roles of stress protein hsp105 during mouse embryo development.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

高分子量ストレス蛋白質の構造と機能Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

高分子量ストレス蛋白質の構造と機能Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

癌細胞および正常細胞における熱ショック蛋白質発現機構とその修飾因子に関する研究

Principal Investigator

Project Period (FY)

Research Category

Research Institution

癌細胞および正常細胞における熱ショック蛋白質発現機構とその修飾因子に関する研究

Principal Investigator

Project Period (FY)

Research Category

Research Institution

癌細胞および正常細胞における熱ショック蛋白質発現機構とその修飾因子に関する研究

Principal Investigator

Project Period (FY)

Research Category

Research Institution

温熱耐性の発現機構の解明とその修飾に関する研究

Principal Investigator

Project Period (FY)

Research Category

Research Institution

温熱耐性の発現機構の解明とその修飾に関する研究

Principal Investigator

Project Period (FY)

Research Category

HATAYAMA Takumi 畑山巧

畑山巧ハタヤマタクミ