MORIMOTO Kazuhiro 森本一洋

Researcher Number	10113135
Other IDs
Affiliation (based on the past Project Information) *help	2004 – 2010: 北海道薬科大学, 薬学部, 教授
Review Section/Research Field	Principal Investigator Medical pharmacy / Physical pharmacy Except Principal Investigator Applied veterinary science
Keywords	Principal Investigator DDS / 肺細胞 / Drug delivery system / Respiratory infection / Alveolar macrophages / Pulmonary administration / Ciprofloxacin / Liposome / ドラッグデリバリーシステム / 呼吸器系感染症 … More / リポソーム製剤 / 肺胞マクロファージ / 抗生物質 / 呼吸器感染症 / 細胞内寄生菌 / 呼吸器 / 感染症 … More Except Principal Investigator Leishmania (V.) panamensis / Leishmania (L.) tropica / Leishmania (L.) major / heat shock protein 70 / レコンビナント抗原 / Leishmania(L.)tropica / Leishmania(L.)major / パキスタン / 皮膚リーシュマニア症 / Phlebotomus / Sergentomyia / 輸入イヌリーシュマニア症 / リポソーム製剤 / 吸血源動物 / サシチョウバエ / クアシノイド / 媒介昆虫 / 伝播機構 / 疫学 / 治療 / 診断 / リーシュマニア症 / 人獣共通感染症 Less

Making of treatment system of respiratory infections disease by application of translational mechanisms in lung cellsPrincipal Investigator
- Principal Investigator
  
  MORIMOTO Kazuhiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Hokkaido Pharmaceutical University School of Pharmacy
Establishment of diagnosis systems and development of chemotherapeutic drugs for leishmaniasis
- Principal Investigator
  
  KATAKURA Ken
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied veterinary science
- Research Institution
  Hokkaido University
Drug delivery systems by pulmonary administration for treatment of respiratory infections.Principal Investigator
- Principal Investigator
  
  MORIMOTO Kazuhiro
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Hokkaido Pharmaceutical University

All 2011 2010 2009 2008 2006 Other

All Journal Article Presentation

[Journal Article] Efficient drug delivery to lung epithelial lining fluid by aerosolization of ciprofloxacin incorporated into PEGylated liposomes for treatment of respiratory infections.2011
- Author(s)
  S. Chono, H. Suzuki, K. Togami, K. Morimoto
- Journal Title
  
  J Drug Dev.Ind.Pharm 37
  
  Pages: 367-372
- Data Source
  KAKENHI-PROJECT-20590039
[Journal Article] Aerosol-based efficient delivery of telithromycin, a ketolide antimicrobial agent, to lung epithelial lining fluid and alveolar macrophages for treatment of respiratory infections.2010
- Author(s)
  K. Togami, S. Chono, T. Seki, K. Morimoto
- Journal Title
  
  J Drug Dev.Ind.Pharm 36(7)
  
  Pages: 861-866
- Data Source
  KAKENHI-PROJECT-20590039
[Journal Article] Effect of surface-mannose modification on aerosolized liposomal delivery to alveolar macrophages.2010
- Author(s)
  S. Chono, K. Kaneko, E. Yamamoto, K. Togami, K.Morimoto
- Journal Title
  
  Drug Dev.Ind.Pharm 36(1)
  
  Pages: 102-107
- Data Source
  KAKENHI-PROJECT-20590039
[Journal Article] Intracellular pharmacokinetics of telithromycin, a ketolide antibiotic, in alveolar macrophages.2010
- Author(s)
  K. Togami, S. Chono, T. Seki, K. Morimoto
- Journal Title
  
  J.Pharm.Pharmacol 62
  
  Pages: 71-75
- Data Source
  KAKENHI-PROJECT-20590039
[Journal Article] Distribution characteristics of telithromycin, a novel ketolide antimicrobial agent applied for treatment of respiratory infection, in lung epithelial lining fluid and alveolar macrophages.2009
- Author(s)
  K. Togami, S. Chono, T. Seki, K. Morimoto
- Journal Title
  
  Drug Metab.Pharmacokin 24(5)
  
  Pages: 411-417
- NAID
  130004463090
- Data Source
  KAKENHI-PROJECT-20590039
[Journal Article] Aerosolized liposomes with dipalmitoyl phosphatidylcholine enhance pulmonary insulin delivery.2009
- Author(s)
  S. Chono, R. Fukuchi, T. Seki, K. Morimoto
- Journal Title
  
  J.Control.Rel 137
  
  Pages: 104-109
- Data Source
  KAKENHI-PROJECT-20590039
[Journal Article] Efficient drug delivery to alveolar macrophages and lung epithelial lining fluid following pulmonary administration of liposomal ciprofloxacin in rats with infectious pneumonia and estimation of its antibacterial effects.2008
- Author(s)
  S. Chono, T. Tanino, T. Seki, K. Morimoto
- Journal Title
  
  Drug Dev.lnd.Pharm 34
  
  Pages: 1090-1096
- Data Source
  KAKENHI-PROJECT-20590039
[Journal Article] Efficient drug targeting to rat alveolar macrophages by pulmonary administration of ciprofloxacin incorporated into mannosylated liposomes for treatment of respiratory intracellular parasitic infections.2008
- Author(s)
  S. Chono, T. Tanino, T. Seki, K. Morimoto
- Journal Title
  
  J.Control.Rel 127
  
  Pages: 50-58
- Data Source
  KAKENHI-PROJECT-20590039
[Journal Article] Distribution Characteristics of Orally Administered Olamufloxacin, a Newly Synthesized Fluoroquinolone Antibacterial, in Lung Epithelial Lining Fluid and Alveolar Macrophage in Rats2006
- Author(s)
  Jin Sun, Yoshiharu Deguchi, Yoshihiko Tauchi, Zhonggui He, Gang Cheng, Kazuhiro Morimoto
- Journal Title
  
  Eur.J.Pharm.Biopharm. (印刷中)
- Data Source
  KAKENHI-PROJECT-16590117
[Journal Article] Distribution characteristics of orally administered olamufloxacin, a newly synthesized fluoroquinolone antibacterial, in lung epithelial lining fluid and alveolar macrophage in rats.
- Author(s)
  J.Sun, Y.Deguchi, Y.Tauchi, Z.He, G.Cheng, K.Morimoto
- Journal Title
  
  Eur.J.Pharm.Biopharm. (印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590117
[Journal Article] Distribution characteristics of orally administered olamufloxacin, a newly synthesized fluoroquinolone antibacterial, in lung epithelial lining fluid and alveolar macrophage in rats.
- Author(s)
  J.Sun, Y.Deguchi, Y.Tauchi, Z.He, G.Cheng, K.Morimoto
- Journal Title
  
  Eur.J.Pharm.Biopharm. (印刷中)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590117
[Journal Article] Influence of particle size on drug delivery to alveolar macrophages by pulmonary administration of ciprofloxacin incorporated into liposomes in rat.
- Author(s)
  S.Chono, T.Tanino, T.Seki, K.Morimoto
- Journal Title
  
  J.Drug Target. (印刷中)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590117
[Journal Article] Influence of particle size on drug delivery to alveolar macrophages by pulmonary administration of ciprofloxacin incorporated into liposomes in rat.
- Author(s)
  S.Chono, T.Tanino, T.Seki, K.Morimoto
- Journal Title
  
  J.Drug Target. (印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590117
[Presentation] 肺薬物送達システムのキャリアーとしてのPEG修飾リボソームの有用性2011
- Author(s)
  山本えり、丁野純男、森本一洋
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-20590039
[Presentation] Distribution mechanisms of macrolide antibiotics in lung epithelial lining fluid and alveolar macrophages for the therapy of respiratory infections2010
- Author(s)
  K.Morimoto, K.Togami, S. Chono
- Organizer
  2010 AAPS Annual Meeting and Exposition
- Place of Presentation
  New Orleans. LA. USA.
- Data Source
  KAKENHI-PROJECT-20590039
[Presentation] 呼吸器感染症の最適化を目的としたマクロライド及びケトライド系抗生物質の肺組織内動態解析2010
- Author(s)
  森本一洋、戸上紘平、丁野純男
- Organizer
  第7回マクロライド研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590039
[Presentation] 呼吸器感染症治療薬であるマクロライド及びケトライド系抗菌薬の肺粘液層及び肺胞マクロファージ分布2010
- Author(s)
  戸上紘平、丁野純男、森本一洋
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-20590039
[Presentation] Distribution mechanisms of macrolide antibiotics in lung epithelial lining fluid and alveolar macrophages for the therapy of respiratory infections2010
- Author(s)
  K.Morimoto
- Organizer
  3^<rd> Indo-Japanese international joint symposium on overcoming interactive diseases prevalent in Asian countries
- Place of Presentation
  Tokyo
- Year and Date
  2010-12-13
- Data Source
  KAKENHI-PROJECT-20590039
[Presentation] 呼吸器感染症治療の適正化を目的としたマクロライド系抗菌薬の肺組織中濃度からみたAUC/MICの評価2010
- Author(s)
  宮崎誠、戸上紘平、丁野純男、森本一洋, 掛見正郎
- Organizer
  第25回薬物動態学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590039
[Presentation] Distribution mechanisms of macrolide antibiotics in lung epithelial lining fluid and alveolar macrophages for the therapy of respiratory infections2010
- Author(s)
  K.Morimoto, K.Togami, S. Chono
- Organizer
  3^<rd> Indo-Japanese international joint symposium on overcoming interactive diseases prevalent in Asian countries
- Place of Presentation
  Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-20590039
[Presentation] Distribution mechanisms of macrolide antibiotics in lung epithelial lining fluid and alveolar macrophages for the therapy of respiratory infections2010
- Author(s)
  K.Morimoto
- Organizer
  2010 AAPS Annual Meeting and Exposition
- Place of Presentation
  New Orleans, LA, USA
- Year and Date
  2010-11-17
- Data Source
  KAKENHI-PROJECT-20590039
[Presentation] 各種マクロライド系抗菌薬の肺組織移行特性に関する検討2009
- Author(s)
  戸上紘平、丁野純男、森本一洋
- Organizer
  日本薬剤学会第24年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-20590039
[Presentation] 肺細胞のトランスレーショナル機構を利用した難治性肺感染症治療システムの構築2009
- Author(s)
  森本一洋
- Organizer
  第48回日本薬学会東北支部特別講演
- Place of Presentation
  仙台
- Year and Date
  2009-10-18
- Data Source
  KAKENHI-PROJECT-20590039
[Presentation] 肺細胞のトランスレーショナル機構を利用した難治性肺感染症治療システムの構築2009
- Author(s)
  森本一洋
- Organizer
  第48回日本薬学会東北支部特別講演
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-20590039
[Presentation] 薬物肺投与システムのキャリアーとしての表面修飾リボソームの有用性2009
- Author(s)
  森本一洋、金子圭太、戸上紘平、丁野純男
- Organizer
  第25回日本DDS学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590039
[Presentation] 薬物肺投与システムのキャリアーとしての表面修飾リポソームの有用性2009
- Author(s)
  森本一洋
- Organizer
  第25回日本DDS学会
- Place of Presentation
  東京
- Year and Date
  2009-07-03
- Data Source
  KAKENHI-PROJECT-20590039
[Presentation] Distribution mechanisms of macrolide antibiotics in lung epithelial lining fluid and alveolar macrophages for the therapy of respiratory infections2009
- Author(s)
  K.Morimoto, K.Togami, S. Chono
- Organizer
  2009 AAPS Annual Meeting and Exposition
- Place of Presentation
  Los Angeles, USA
- Data Source
  KAKENHI-PROJECT-20590039
[Presentation] ニューキノロン系抗菌薬の肺胞マクロファージ移行特性の検討2009
- Author(s)
  鈴木宏和、戸上紘平、丁野純男、森本一洋
- Organizer
  日本薬剤学会第24年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-20590039
[Presentation] 呼吸器感染症治療の最適化を目的としたマクロライド及びケトライド系抗生物質の肺組織内動態解析2009
- Author(s)
  戸上紘平、丁野純男、森本一洋
- Organizer
  第16回マクロライド新作用研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590039
[Presentation] フルオロキノロン系抗菌薬の肺表面及び肺胞マクロファージにおける動態特性2009
- Author(s)
  鈴木宏和、戸上紘平、丁野純男、森本一洋
- Organizer
  第24回日本薬物動態学会年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20590039
[Presentation] Pharmacokinetical analysis of telithromycin in lung for safe therapy of respiratory infections2008
- Author(s)
  Kazuhiro Morimoto
- Organizer
  World congress of pharmacy and pharmaceutical sciences 2008 68^<th>) International congress of FIP
- Place of Presentation
  Basel, Switzerland
- Year and Date
  2008-09-01
- Data Source
  KAKENHI-PROJECT-20590039

1. NONAKA Nariaki (50281853)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. CHONO Sumio (90347790)

# of Collaborated Projects: 2 results

# of Collaborated Products: 22 results
3. KATAKURA Ken (10130155)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. MATSUMOTO Jun (70296169)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. SEKI Toshinobu (60196946)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

MORIMOTO Kazuhiro 森本 一洋

Research Projects

Research Products

Co-Researchers

Making of treatment system of respiratory infections disease by application of translational mechanisms in lung cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of diagnosis systems and development of chemotherapeutic drugs for leishmaniasis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Drug delivery systems by pulmonary administration for treatment of respiratory infections.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Efficient drug delivery to lung epithelial lining fluid by aerosolization of ciprofloxacin incorporated into PEGylated liposomes for treatment of respiratory infections.2011

Author(s)

Journal Title

Data Source

[Journal Article] Aerosol-based efficient delivery of telithromycin, a ketolide antimicrobial agent, to lung epithelial lining fluid and alveolar macrophages for treatment of respiratory infections.2010

Author(s)

Journal Title

Data Source

[Journal Article] Effect of surface-mannose modification on aerosolized liposomal delivery to alveolar macrophages.2010

Author(s)

Journal Title

Data Source

[Journal Article] Intracellular pharmacokinetics of telithromycin, a ketolide antibiotic, in alveolar macrophages.2010

Author(s)

Journal Title

Data Source

[Journal Article] Distribution characteristics of telithromycin, a novel ketolide antimicrobial agent applied for treatment of respiratory infection, in lung epithelial lining fluid and alveolar macrophages.2009

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Aerosolized liposomes with dipalmitoyl phosphatidylcholine enhance pulmonary insulin delivery.2009

Author(s)

Journal Title

Data Source

[Journal Article] Efficient drug delivery to alveolar macrophages and lung epithelial lining fluid following pulmonary administration of liposomal ciprofloxacin in rats with infectious pneumonia and estimation of its antibacterial effects.2008

Author(s)

Journal Title

Data Source

[Journal Article] Efficient drug targeting to rat alveolar macrophages by pulmonary administration of ciprofloxacin incorporated into mannosylated liposomes for treatment of respiratory intracellular parasitic infections.2008

Author(s)

Journal Title

Data Source

[Journal Article] Distribution Characteristics of Orally Administered Olamufloxacin, a Newly Synthesized Fluoroquinolone Antibacterial, in Lung Epithelial Lining Fluid and Alveolar Macrophage in Rats2006

Author(s)

Journal Title

Data Source

[Journal Article] Distribution characteristics of orally administered olamufloxacin, a newly synthesized fluoroquinolone antibacterial, in lung epithelial lining fluid and alveolar macrophage in rats.

Author(s)

Journal Title

Description

Data Source

[Journal Article] Distribution characteristics of orally administered olamufloxacin, a newly synthesized fluoroquinolone antibacterial, in lung epithelial lining fluid and alveolar macrophage in rats.

Author(s)

Journal Title

Description

Data Source

[Journal Article] Influence of particle size on drug delivery to alveolar macrophages by pulmonary administration of ciprofloxacin incorporated into liposomes in rat.

Author(s)

Journal Title

Description

Data Source

[Journal Article] Influence of particle size on drug delivery to alveolar macrophages by pulmonary administration of ciprofloxacin incorporated into liposomes in rat.

Author(s)

Journal Title

Description

Data Source

[Presentation] 肺薬物 送達システムのキャリアーとしてのPEG修 飾リボソームの有用性2011

MORIMOTO Kazuhiro 森本一洋

[Presentation] 肺薬物送達システムのキャリアーとしてのPEG修飾リボソームの有用性2011