Hara Akira 原晃

… Alternative Names

原晃ハラアキラ

HARA Akira 原晃

HARA A 原晃

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Researcher Number	10156474
Other IDs
External Links
Affiliation (Current)	2025: 筑波大学, 医学医療系, 教授
Affiliation (based on the past Project Information) *help	2012 – 2016: 筑波大学, 医学医療系, 教授 1997 – 2001: 筑波大学, 臨床医学系, 助教授 1989 – 1993: 筑波大学, 臨床医学系, 助教授
Review Section/Research Field	Principal Investigator Otorhinolaryngology Except Principal Investigator Otorhinolaryngology / Otorhinolaryngology
Keywords	Principal Investigator NO / Free radicals / フリーラジカル / Acoustic trauma / Iron chelator / Steroid hormone / Transient ischemia / Hydrnxyl radicals / Cochlear dysfunction / マンニトール … More / 虚血 / 鉄 / NOS阻害薬 / ヒドロモシルラジカル / フリーラジカルスカベンジャー / アスフィキシア / 音響外傷 / 鉄キレート剤 / ステロイドホルモン / 一過性虚血 / ヒドロキシルラジカル / 内耳性難聴 / Lipid hydroperoxides / Metallic elements / Cochlea / 過酸化脂質 / 金属イオン / 内耳蝸牛 … More Except Principal Investigator nNOS / iNOS / NO / カルモデュリン / 蝸牛神経複合活動電位 / 鉄イオン / 蝸牛 / OH / Free Radicals / Ischemia-reperfusion Injury / Transient Ischemia / Cochlea / マンニットール / Mn-SOD / A1アデノシン受容体作動薬 / PARS抑制剤 / NMDA受容体拮抗剤 / NOS阻害剤 / ステロイドホルモン / Phospholipase A2 / PARS / 蝸牛神経活動電位 / 蝸牛一過性アノキシア / 蝸牛一過性虚血 / OH^・ / フリーラジカル / 虚血再灌流傷害 / 一過性虚血 / Trace elements / Perilympha / Cervical sympathetic nerve / Olivo-cochlear bundle / Acoustic overstimulation / Endolymphatic hydrops / Transient anoxia / フロセミド / 蝸午電位 / 内耳液 / 低体温 / 強大音 / 蝸牛電位 / 内耳循環障害 / 内耳性難聴 / 耳音響放射 / マグネシウムイオン / 内リンパ電位 / スーパーオキシド / 頚部交感神経 / 微量元素 / 外リンパ液 / 頚部支感神経 / 蝸牛遠心性線維 / 強大音負荷 / 内リンパ水腫 / 一過性アノキシア / 耳毒性 / 有毛細胞 / シスプラチン / 内耳 Less

Effects of ceramide and sphingolipids on cochlear injury
- Principal Investigator
  
  Tabuchi Keiji
- Project Period (FY)
  2012 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  University of Tsukuba
Cochlear Dysfunction and Free Radicals : hydroxyl radicals, metallic elements, steroid hormones and SODPrincipal Investigator
- Principal Investigator
  
  HARA Akira
- Project Period (FY)
  1998 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  University of Tsukuba
The role of free radicals in cochlear circulatory disorders.
- Principal Investigator
  
  KUSAKARI Jun
- Project Period (FY)
  1997 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  Otorhinolaryngology
- Research Institution
  University of Tsukuba, Institute of Clinical Medicine
Quantitative analysis of free radicals in cochleaPrincipal Investigator
- Principal Investigator
  
  HARA Akira
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  University of Tsukuba
The basic studies on the diagnosis and treatment of inner ear deafness.
- Principal Investigator
  
  KUSAKARI Jun
- Project Period (FY)
  1989 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  University of Tsukuba

All 2017 2016 2015 2014 2012

All Journal Article Presentation

[Journal Article] The role of peroxiredoxin I in cisplatin-induced ototoxicity2017
- Author(s)
  Le Q, Tabuchi K, Warabi E, Hara A
- Journal Title
  
  Auris Nasus Larynx
  
  Volume: 44 Pages: 205-212
- Data Source
  KAKENHI-PROJECT-24592541
[Journal Article] Hair Cell Loss Induced by Sphingosine and a Sphingosine Kinase Inhibitor in the Rat Cochlea.2016
- Author(s)
  Tani K, Tabuchi K, Hara A
- Journal Title
  
  Neurotoxicology Research
  
  Volume: 29 Issue: 1 Pages: 35-46
- DOI
  10.1007/s12640-015-9563-7
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24592541
[Journal Article] Ceramide/sphingomyelin cycle involvement in gentamicin-induced cochlear hair cell death.2015
- Author(s)
  Chi L, Tabuchi K, Nakamagoe M, Nakayama M, Hara A
- Journal Title
  
  Arch Toxicol
  
  Volume: 89 Issue: 3 Pages: 415-421
- DOI
  10.1007/s00204-014-1259-x
- NAID
  120007130316
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24592541
[Journal Article] The influence of sphingosine-1-phosphate receptor antagonists on gentamicin-induced hair cell loss of the rat cochlea.2014
- Author(s)
  Nakayama M, Tabuchi K,Hoshino T, Nakamagoe M, Nishimura B, Hara A
- Journal Title
  
  Neuroscience Letters
  
  Volume: 561 Pages: 91-95
- DOI
  10.1016/j.neulet.2013.12.063
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592541
[Journal Article] The effects of A1 and A2A adenosine receptor agonists on kainic acid excitotoxicity in the guinea pig cochlea.2012
- Author(s)
  Tabuchi K, Sakai S, Nakayama M, Nishimura B, Hayashi K, Hirose Y, Hara A
- Journal Title
  
  Neurosci Lett
  
  Volume: 518 Issue: 1 Pages: 60-63
- DOI
  10.1016/j.neulet.2012.04.057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592541
[Presentation] Hair Cell Loss Induced by Sphingosine and a Sphingosine Kinase Inhibitor in the Rat Cochlea.2016
- Author(s)
  Tani K, Tabuchi K, Hara A
- Organizer
  2015 ARO Midwinter meeting
- Place of Presentation
  Baltimore, USA
- Year and Date
  2016-02-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24592541
[Presentation] Ceramide/sphingomyelin cycle involvement in gentamicin-induced cochlear hair cell death.2015
- Author(s)
  Chi L, Tabuchi K, Hara A
- Organizer
  ARO midwinter meeting
- Place of Presentation
  Marriott Hotel Baltimore (Baltimore, USA)
- Year and Date
  2015-02-21
- Data Source
  KAKENHI-PROJECT-24592541
[Presentation] ゲンタマイシン耳毒性における蝸牛外有毛細胞アポトーシスに対するスフィンゴシン1リン酸受容体アンタゴニストの影響2012
- Author(s)
  中山雅博、田渕経司、西村文吾、中馬越真理子、原　晃
- Organizer
  第112回日本耳鼻咽喉科学会
- Place of Presentation
  朱鷺メッセ
- Data Source
  KAKENHI-PROJECT-24592541
[Presentation] ゲンタマイシン耳毒性におけるスフィンゴ脂質代謝産物の影響2012
- Author(s)
  西村文吾、田渕経司、中山雅博、中馬越真理子、Chi LNU、原　晃
- Organizer
  第23回日本耳科学会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Data Source
  KAKENHI-PROJECT-24592541

1. TAKAHASHI K (70197135)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. TAKEYAMA M (60179679)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. KUSAKARI Jun (00004705)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. SENARITA Masamitsu (60282357)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. Tabuchi Keiji (80361335)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
6. NISHIKAWA N (60237675)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. ASE Y (00013920)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. WADA Tetsuro (10282360)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. ITO Zenya (20241812)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Hara Akira 原 晃

原 晃 ハラ アキラ

HARA Akira 原 晃

HARA A 原 晃

Research Projects

Research Products

Co-Researchers

Effects of ceramide and sphingolipids on cochlear injury

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Cochlear Dysfunction and Free Radicals : hydroxyl radicals, metallic elements, steroid hormones and SODPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of free radicals in cochlear circulatory disorders.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Quantitative analysis of free radicals in cochleaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The basic studies on the diagnosis and treatment of inner ear deafness.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] The role of peroxiredoxin I in cisplatin-induced ototoxicity2017

Author(s)

Journal Title

Data Source

[Journal Article] Hair Cell Loss Induced by Sphingosine and a Sphingosine Kinase Inhibitor in the Rat Cochlea.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ceramide/sphingomyelin cycle involvement in gentamicin-induced cochlear hair cell death.2015

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] The influence of sphingosine-1-phosphate receptor antagonists on gentamicin-induced hair cell loss of the rat cochlea.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The effects of A1 and A2A adenosine receptor agonists on kainic acid excitotoxicity in the guinea pig cochlea.2012

Author(s)

Journal Title

DOI

Data Source

[Presentation] Hair Cell Loss Induced by Sphingosine and a Sphingosine Kinase Inhibitor in the Rat Cochlea.2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Ceramide/sphingomyelin cycle involvement in gentamicin-induced cochlear hair cell death.2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] ゲンタマイシン耳毒性における蝸牛外有毛細胞アポトーシスに対するスフィンゴシン1リン酸受容体アンタゴニストの影響2012

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] ゲンタマイシン耳毒性におけるスフィンゴ脂質代謝産物の影響2012

Hara Akira 原晃

原晃ハラアキラ

HARA Akira 原晃

HARA A 原晃