NAKAMURA Magumi 中村愛

… Alternative Names

NAKAMURA MEGUMI 中村愛

中村愛ナカムラメグミ

Less

Researcher Number	10159072
Affiliation (based on the past Project Information) *help	2012: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究助手 2001: (財)東京都老人総合研究所, 蛋白質生化学, 研究助手 2000 – 2001: (財)東京都老人総合研究所, 蛋白質生化学部門, 研究助手 1995: (財)東京都老人総合研究所, 酵素生化学部門, 助手
Review Section/Research Field	Except Principal Investigator Functional biochemistry / Laboratory medicine / General medical chemistry
Keywords	Except Principal Investigator PLASMA MEMBRANE / PLATELET / PERFRINGOLYSINO / RAFTS / LIPID DOMAIN / CHOLESTEROL / β-シクロデキストリン / コレステロール結合毒素 / Perfringolysin O / ラフト … More / 細胞膜 / 血小板 / perfringolysin O / コレステロール / カルボニル化タンパク質 / 軽度認知障害 / 臨床検査医学 / プロテオーム解析 / 髄液バイオマーカー / 認知症 / 酸化タンパク質 / 髄液マーカー / 神経変性疾患 / バイオマーカー / 病態検査医学 / カルパイン / クリスタリン / 蛋白質分解 / 白内障 Less

Proteomic investigation of oxidized proteins in cerebrospinal fluid for developing novel biomarkers of Alzheimer's disease.
- Principal Investigator
  
  TODA Tosifusa
- Project Period (FY)
  2008 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
  Tokyo Metropolitan Institute of Gerontology
Visualization and functional analysis of cholesterol-rich membrace microdomains with a new probe
- Principal Investigator
  
  IWASHITA YOSHIKO
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tokyo Metropolitan Institute of Gerontology
遺伝性白内障ラットを用いた白内障発症過程における蛋白質分解機構とその意義の解析
- Principal Investigator
  
  猪股光司
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Tokyo Metropolitan Institute of Gerontology

All 2012 2011 2010 2009 2008

All Journal Article Presentation

[Journal Article] Differential responses of white adipose tissue and brown adipose tissue to caloric restriction in rats.2012
- Author(s)
  Okita N, Hayashida Y, Kojima Y, Fukushima M, Yuguchi K, Mikami K, Yamauchi A, Watanabe K, Noguchi M, Nakamura M, Toda T, Higami Y.
- Journal Title
  
  Mech Ageing Dev.
  
  Volume: 133(5) Issue: 5 Pages: 255-266
- DOI
  10.1016/j.mad.2012.02.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590594
[Journal Article] Proteomic approaches to oxidative protein modifications implicated in the mechanism of aging2012
- Author(s)
  Toda T, Nakamura M, Morisawa H, Hirota M, Nishigaki R, Yoshimi Y.
- Journal Title
  
  Geriatr Gerontol Int
  
  Volume: 10(Suppl.1)
- NAID
  10027272777
- Data Source
  KAKENHI-PROJECT-20590594
[Journal Article] proteomic identification of differentially expressed genes in neural stem cells and neurons differentiated from embryonic stem cells of cynomolgus monkey (Macaca fascicularis) in vitro2011
- Author(s)
  Akama K, Horikoshi T, Nakayama T, Otsu M, Imaizumi N, Nakamura M, Toda T, Inuma M, Hirano H, Kondo Y, Suzuki Y, Inoue N.
- Journal Title
  
  Biochim Biophys Acta.
  
  Volume: 1814 Issue: 2 Pages: 265-276
- DOI
  10.1016/j.bbapap.2010.10.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590594
[Journal Article] Up-regulation of 42 kDa tubulin alpha-6 chain fragment in well-differentiated hepatocellular carcinoma tissues from patients infected with hepatitis C virus2011
- Author(s)
  Kuramitsu Y, Takashima M, Yokoyama Y, Iizuka N, Tamesa T, Akada JK, Wang Y, Toda T, Sakaida I, Okita K, Oka M, Nakamura K.
- Journal Title
  
  Anticancer Res.
  
  Volume: 31(10) Pages: 3331-3336
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590594
[Journal Article] Proteomic approaches to oxidative protein modifications implicated in the mechanism of aging2010
- Author(s)
  Toda T, Nakamura M, Morisawa H, Hirota M, Nishigaki R, Yoshimi Y.
- Journal Title
  
  Geriatrics and Gerontology International
  
  Volume: 10(Supp1.1)
- NAID
  10027272777
- Data Source
  KAKENHI-PROJECT-20590594
[Journal Article] Protein disulfide isomerase-P5, down-regulated in the final stage of boar epididymal sperm maturation, catalyzes disulfide formation to inhibit protein function in oxidative refolding of reduced denatured lysozyme.2010
- Author(s)
  Akama K, Horikoshi T, Sugiyama A, Nakahata S, Akitsu A, Niwa N, Intoh A, Kakui Y, Sugaya M, Takei K, Imaizumi N, Sato T, Matsumoto R, Iwahashi H, Kashiwabara SI, Baba T, Nakamura M, Toda T.
- Journal Title
  
  Biochim Biophys Acta.
  
  Volume: 1804(6) Issue: 6 Pages: 1272-1284
- DOI
  10.1016/j.bbapap.2010.02.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590594, KAKENHI-PLANNED-21112005, KAKENHI-PROJECT-21248038, KAKENHI-PROJECT-22580384
[Journal Article] Proteomic approaches to oxidative protein modifications implicated in the mechanism of aging2010
- Author(s)
  Toda T, Nakamura M, Morisawa H, Hirota M, Nishigaki R, Yoshimi Y.
- Journal Title
  
  Geriatrics Gerontology International 10(Supplement 1)
- NAID
  10027272777
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590594
[Journal Article] Protein disulfide isomerase-P5, down-regulated in the final stage of boar epididymal sperm maturation, catalyzes disulfide formation to inhibit protein function in oxidative refolding of reduced denatured lysozyme2010
- Author(s)
  Akama K, Horikoshi T, Sugiyama A, Nakahata S, Akitsu A, Niwa N, Intoh A, Kakui Y, Sugaya M, Takei K, Imaizumi N, Sato T, Matsumoto R, Iwahashi H, Kashiwabara SI,Baba T, Nakamura M, Toda T.
- Journal Title
  
  Biochimica et Biophysics Acta
  
  Volume: 1804 Pages: 1272-1284
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590594
[Journal Article] Glycoproteomic analysis of abnormal N-glycosylation on the kappa chain of cryocryst alglobulin in a patient of multiple myeloma2009
- Author(s)
  Toda T, Nakamura M, Yamada M, Nishine T, Torii T, Ikenaka K, Mori M.
- Journal Title
  
  J. Electrophoresis 53
  
  Pages: 1-6
- NAID
  10025191936
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590594
[Journal Article] ラミンA-その多彩な機能と老化-2009
- Author(s)
  中村愛、森澤拓、戸田年総
- Journal Title
  
  基礎老化研究 33
  
  Pages: 3-10
- NAID
  10026103704
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590594
[Journal Article] Glycoproteomic analysis of abnormal N-glycosylation on the kappa chain of cryocryst alglobulin in a patient of multiple myeloma2009
- Author(s)
  Toda T, Nakamura M, Yamada M, Nishine T, Torii T, Ikenaka K, Mori M.
- Journal Title
  
  J. Electrophoresis
  
  Volume: 53 Pages: 1-6
- NAID
  10025191936
- URL
  http://dx.doi.org/10.2198/jelectroph.53.7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590594
[Journal Article] Proteomic analysis of protein complexes in human SH-SY5Y neuroblastoma cells by using blue-native gel electrophoresis : An increase in lamin A/C associated with heat shock protein 90 in response to 6-hydroxydopamine-induced oxidative stress2009
- Author(s)
  Nakamura M, Morisawa H, Imajoh-Ohmi S, Takamura C, Fukuda H, Toda T.
- Journal Title
  
  Exp. Gerontol.
  
  Volume: 44(6-7) Pages: 375-382
- URL
  http://dx.doi.org/10.1016/j.exger.2009.02.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590594
[Journal Article] Proteomic analysis of protein complexes in human SH-SY5Y neuroblastoma cells by using blue-native gel electrophoresis : An increase in lamin A/C associated with heat shock protein 90 in response to 6-hydroxydopamine-induced oxidative stress2009
- Author(s)
  Nakamura M, Morisawa H, Imajoh-Ohmi S, Takamura C, Fukuda H, Toda T
- Journal Title
  
  Experimental Gerontology 44
  
  Pages: 375-382
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590594
[Journal Article] Proteomic analysis of protein complexes in human SH-SY5Y neuroblastoma cells by using blue-native gel electrophoresis : An increase in lamin A/C associated with heat shock protein 90 in response to 6-hydroxydopamine-induced oxidative stress2009
- Author(s)
  Nakamura M, Morisawa H, Imajoh-Ohmi S, Takamura C, Fukuda H, Toda T
- Journal Title
  
  Experimental.Gerontology 44(6-7)
  
  Pages: 375-382
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590594
[Journal Article] Proteomic identification of differentially expressed genes in ouse neural stem cells and neurons differentiated from embryonic stem cells in vitro2008
- Author(s)
  Akama K, Tatsuno R. Otsu M, Horikoshi T, Nakamura M, Toda T, Inoue N
- Journal Title
  
  Biochim. Biophys. Acta. 1784
  
  Pages: 773-782
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590594
[Presentation] Proteomic identification of differentially expressed genes during differentiation of cynomolgus monkey embryonic stem cells to astrocyte progenitor cells in vitro2012
- Author(s)
  Kuniko Akama1, Tomoe Horikoshi, Takashi Nakayama, Masahiro Otsu, Noriaki Imaizumi, Megumi Nakamura, Tosifusa Toda, Michiko Inuma, Hisashi Hirano, Yasushi Kondo, Yutaka Suzuki, Nobuo Inoue
- Organizer
  HUPO 11th Annual World Congress
- Place of Presentation
  ボストン、米国
- Data Source
  KAKENHI-PROJECT-20590594
[Presentation] 酸化ストレスによるラミンのリン酸化と分子シャペロン複合体形成のプロテオーム解析2010
- Author(s)
  戸田年総、中村愛
- Organizer
  日本電気泳動学会第62回総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-20590594
[Presentation] 酸化ストレスによるラミンのリン酸化と分子シャペロン複合体形成のプロテオーム解析2010
- Author(s)
  戸田年総、中村愛
- Organizer
  第61回日本電気泳動学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-20590594
[Presentation] Neural stem sphere法によるサルの初期神経発生のプロテオーム解析2010
- Author(s)
  赤間邦子、堀越朋恵、中山孝、大津昌弘、今泉紀明、中村愛、戸田年総、近藤靖、鈴木豊、井上順雄
- Organizer
  第53回日本神経化学会大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20590594
[Presentation] ブタ精子成熟過程におけるユビキチン化タンパク質の効率的抽出濃縮法2010
- Author(s)
  今泉紀明、井沼道子、平野久、中村愛、戸田年総、肥後大輔、赤間邦子
- Organizer
  日本ヒトプロテオーム機構第8回大会・第6回日本臨床プロテオーム研究会連合大会
- Place of Presentation
  浦安
- Data Source
  KAKENHI-PROJECT-20590594
[Presentation] ラット白色および褐色脂肪組織におけるカロリー制限に体する応答性の違い2010
- Author(s)
  林田雄介、福島麻由美、小島由美子、沖田直之、中村愛、戸田年総、樋上賀一
- Organizer
  日本基礎老化学会第33回大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20590594
[Presentation] Neural Stem Sphere 法を用いたサルES細胞から神経幹細胞への分化過程における発現量変化解析2009
- Author(s)
  今泉紀明, 堀越朋恵, 中山孝, 大津昌弘, 赤間邦子, 中村愛, 戸田年総, 近藤靖, 鈴木豊, 井上順雄
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20590594
[Presentation] 二次元目にTris-Tricine緩衝液系SDS-電気泳動を用いた場合のスタッキング効果に影響を及ぼす緩衝液条件の検討:ミニゲル二次元電気泳動のための泳動条件の最適化2009
- Author(s)
  戸田年総, 中村愛, 廣田三佳子, 森澤拓
- Organizer
  第60回日本電気泳動学会総会
- Place of Presentation
  松本
- Data Source
  KAKENHI-PROJECT-20590594
[Presentation] Proteome Analysis of Carbonyl Proteins in Cerebrospinal Fluid by Cy5-Hyedrazide Labeling2009
- Author(s)
  Toda T, Nakamura M, Shibasaki FT, Yoshizawa T.
- Organizer
  HUPO 8th Annual World Congress
- Place of Presentation
  Tronto、Canada
- Data Source
  KAKENHI-PROJECT-20590594
[Presentation] Neural StemSphere法を用いたサルES細胞から神経幹細胞への分化過程における発現量変化解析2009
- Author(s)
  今泉紀明, 堀越朋恵, 中山孝, 大津昌弘,赤間邦子, 中村愛, 戸田年総, 近藤靖, 鈴木豊, 井上順雄
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20590594
[Presentation] 質量分析データビュワーの改良-プロテオーム研究情報管理のために-2009
- Author(s)
  森澤拓, 中村愛, 廣田三佳子, 戸田年総
- Organizer
  日本ヒトプロテオーム機構第7回大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590594
[Presentation] 酸化ストレス負荷におけるSH-SY5Y細胞のブルーネイティブ二次元電気泳動によるプロテオーム解析(II)2009
- Author(s)
  中村愛, 森澤拓, 戸田年総
- Organizer
  日本ヒトプロテオーム機構第7回大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590594
[Presentation] Neural Stem Sphere 法を用いたサルES細胞から神経への分化における発現比較解析2009
- Author(s)
  今泉紀明, 堀越朋恵, 中山孝, 大津昌弘, 赤間邦子, 中村愛, 戸田年総, 近藤靖, 鈴木豊, 井上順雄
- Organizer
  日本ヒトプロテオーム機構第7回大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590594
[Presentation] 質量分析データビュワーの改良--プロテオーム研究情報管理のために--2009
- Author(s)
  森澤拓, 中村愛, 廣田三佳子, 戸田年総
- Organizer
  日本ヒトプロテオーム機構第7回会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590594
[Presentation] 二時限目に Tris-Tricine 緩衝液系SDS-電気泳動を用いた場合のスタッキング効果に影響を及ぼす緩衝液条件の検討2009
- Author(s)
  戸田年総, 中村愛, 廣田三佳子, 森澤拓
- Organizer
  第60回日本電気泳動学会総会
- Place of Presentation
  松本
- Data Source
  KAKENHI-PROJECT-20590594
[Presentation] Proteome Analysis of Carbonyl Proteins in Cerebrospinal Fluid by Cy5-Hydrazide Labeling2009
- Author(s)
  Tosifusa Toda, Megumi Nakamura, Futoshi shibasaki, Toshihiro Yoshizawa
- Organizer
  HUPO 8th Annual World Congress
- Place of Presentation
  Tronto、Canada
- Data Source
  KAKENHI-PROJECT-20590594
[Presentation] シアニン系蛍光標識試薬を用いたタンパク質フリーチオールレベルの定量分析法に関する基礎的検討2008
- Author(s)
  戸田年総, 中村愛, 森澤拓, 岩本真知子
- Organizer
  第59回日本電気泳動学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590594
[Presentation] An approach to the quantitative analysis of free thiol levels in human CSF proteins by the method of 2-D gel fluoroimaging with using cyanine dyes and fluorescent gel stain2008
- Author(s)
  Tosifusa Toda, Megumi Nakamura, Hiraku Morisawa, Machiko Iwamoto, Junpei Ohkata, Hajime Sato, Hiroshi Tanaka, Kazutomi Kanemaru
- Organizer
  MPSA2008 17th Meeting of Methods in Protein Structure Analysis
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-20590594

1. TODA Tosifusa (80133635)

# of Collaborated Projects: 1 results

# of Collaborated Products: 33 results
2. SHIBASAKI Futoshi (90300954)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. IWASHITA YOSHIKO (50111498)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 猪股光司 (30142649)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

NAKAMURA Magumi 中村 愛

NAKAMURA MEGUMI 中村 愛

中村 愛 ナカムラ メグミ

Research Projects

Research Products

Co-Researchers

Proteomic investigation of oxidized proteins in cerebrospinal fluid for developing novel biomarkers of Alzheimer's disease.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Visualization and functional analysis of cholesterol-rich membrace microdomains with a new probe

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

遺伝性白内障ラットを用いた白内障発症過程における蛋白質分解機構とその意義の解析

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Differential responses of white adipose tissue and brown adipose tissue to caloric restriction in rats.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Proteomic approaches to oxidative protein modifications implicated in the mechanism of aging2012

Author(s)

Journal Title

NAID

Data Source

[Journal Article] proteomic identification of differentially expressed genes in neural stem cells and neurons differentiated from embryonic stem cells of cynomolgus monkey (Macaca fascicularis) in vitro2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Up-regulation of 42 kDa tubulin alpha-6 chain fragment in well-differentiated hepatocellular carcinoma tissues from patients infected with hepatitis C virus2011

Author(s)

Journal Title

Data Source

[Journal Article] Proteomic approaches to oxidative protein modifications implicated in the mechanism of aging2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Protein disulfide isomerase-P5, down-regulated in the final stage of boar epididymal sperm maturation, catalyzes disulfide formation to inhibit protein function in oxidative refolding of reduced denatured lysozyme.2010

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Proteomic approaches to oxidative protein modifications implicated in the mechanism of aging2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Protein disulfide isomerase-P5, down-regulated in the final stage of boar epididymal sperm maturation, catalyzes disulfide formation to inhibit protein function in oxidative refolding of reduced denatured lysozyme2010

Author(s)

Journal Title

Data Source

[Journal Article] Glycoproteomic analysis of abnormal N-glycosylation on the kappa chain of cryocryst alglobulin in a patient of multiple myeloma2009

Author(s)

Journal Title

NAID

Data Source

[Journal Article] ラミンA-その多彩な機能と老化-2009

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Glycoproteomic analysis of abnormal N-glycosylation on the kappa chain of cryocryst alglobulin in a patient of multiple myeloma2009

Author(s)

Journal Title

NAID

URL

Data Source

[Journal Article] Proteomic analysis of protein complexes in human SH-SY5Y neuroblastoma cells by using blue-native gel electrophoresis : An increase in lamin A/C associated with heat shock protein 90 in response to 6-hydroxydopamine-induced oxidative stress2009

Author(s)

NAKAMURA Magumi 中村愛

NAKAMURA MEGUMI 中村愛

中村愛ナカムラメグミ