KAWASE Ichiro 川瀬一郎

… Alternative Names

Researcher Number	10161324
External Links
Affiliation (based on the past Project Information) *help	2008 – 2009: Osaka University, 医学系研究科, 教授 2004: 大阪大学, 大学院・医学系研究科, 教授 2003 – 2004: 大阪大学, 医学系研究科, 教授 1992 – 1993: 大阪大学, 医学部, 講師 1992: 大阪大学, 医学部・第3内科, 講師 … More
Review Section/Research Field	Principal Investigator Respiratory organ internal medicine / Respiratory organ internal medicine Except Principal Investigator Respiratory organ internal medicine / Biological Sciences / Respiratory organ internal medicine
Keywords	Principal Investigator CD9 / テトラスパニン / 肺癌 / アデノウイルスベクター / インターロイキン6 / 間質性肺炎 / 血管新生 / リンパ管新生 / CD151 / インテグリン … More Except Principal Investigator ILー6 / 生体内抗腫瘍効果 / 遺伝子クローニング / ヒトT細胞ハイブリドーマ / キラ-T細胞 / 低免疫原性腫瘍 / ヒト・キラ-T生体内分化 / ヒト癌細胞 / SOCS / PIAS / STAT / キラーT細胞分化因子(KHF) / 生体内キラーT分化 / ILー6遺伝子導入癌細胞 / 腫瘍特異的キラーT / ILー6 cDNAーtransfectant / transfectant腫瘍 / scidーhuマウス / 肺小細胞癌培養株 / Lーmyc癌遺伝子 / 薬剤・放射線耐性 / HLAーclassI抗原 / インタ-フェロン / モノクロ-ナル抗体 / ILー6 cDNA transfectant / SCIDーhuマウス / IL-6遺伝子導入ヒト癌細胞 / SCID-huマウス / アデノウイルスベクター / ヒトキラーT生体内分化 / 生体内遺伝子導入 / IL-6 transgenic SCID / IL-6 transgenic マウス / サイトカイン遺伝子 / IL-6遺伝子 / ヒト・キラーT生体内分化 / IL-6transgenic SCID / 抗腫瘍効果 / キラーT細胞 / 喫煙 / 慢性閉塞性呼吸器疾患 / CYP2A6 / ニコチン依存 / 特発性肺線維症 / テトラスパニン / インテグリン、CD9 / CD151 / 肺線維症 / CD9 / 上皮細胞 / 間質性肺炎 / ヒト / キラーT細胞分化因子 / リンホカイン / T細胞の分化 / LAK活性 / 抗腫瘍免疫 / 生体内効果 / 肺小細胞癌 / 神経細胞接着分子 / モノクローナル抗体 / Small cell lung cancer / Neural cell adhesion molecule / N-CAM / Monoclonal antibody / STAT遺伝子 / SOCS遺伝子 / PIAS遺伝子 / 肺癌 / 細胞増殖 / 薬剤感受性 / 癌抑制 / 増殖抑制 / Jac-STAT / 増殖 / シグナル経路 / JAK / lung cancer / cell growth / chemosensitivity / suppressor of cancer Less

Functional analysis of tetraspanins(CD9, CD151) in lung fibrosis
- Principal Investigator
  
  TAKEDA Yoshito
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Osaka University
Role or tetraspanins in angiogenesis and lymphangiogenesisPrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Ryo, 川瀬一郎
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Osaka University
喫煙による慢性閉塞性呼吸器疾患発症に関する分子疫学的研究
- Principal Investigator
  
  東純一
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Expression of tetraspanins in human lung cancer cells : frequent downregulation of CD9 and its contribution to cell motility in small cell lung cancerPrincipal Investigator
- Principal Investigator
  
  KAWASE Ichiro
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Osaka University
Investigation on the role of SOCS family in the development of lung cancer. and its application to cancer therapy
- Principal Investigator
  
  OSAKI Tadashi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Osaka University
IL-6遺伝子導入と欠損によるヒト・生体(SCIDマウス)内抗腫瘍免疫調節機構
- Principal Investigator
  
  岡田全司
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
  Osaka University
アデノウイルスベクターを用いたIL-6遺伝子導入による間質性肺炎モデル動物の作製Principal Investigator
- Principal Investigator
  
  川瀬一郎
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Osaka University
肺小細胞癌の悪性化のメカニズムの解明とその対策(Lーmyc癌遺伝子の異常と悪性化)
- Principal Investigator
  
  TANIO Yoshiro
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Osaka University
ILー6遺伝子導入と欠損によるヒト・生体(SCIDマウス)内抗腫瘍免疫調節機構の解析
- Principal Investigator
  
  岡田全司
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
Expression and function of neural cell adhesion molecule (N-CAM) in small cell lung cancerPrincipal Investigator
- Principal Investigator
  
  KAWASE Ichiro, 桝野富彌
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Osaka University
ILー6及びILー6遺伝子導入癌細胞による生体内抗腫瘍免疫調節機構の解析
- Principal Investigator
  
  岡田全司
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Osaka University
ILー6による抗腫瘍活性の解析及びILー6と異なるKHFの遺伝子クローニング
- Principal Investigator
  
  岡田全司
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Osaka University
Models of immunotherapy using monoclonal antibodies against human small cell lung cancer.Principal Investigator
- Principal Investigator
  
  KAWASE Ichiro
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Osaka University
T細胞分化因子による抗腫瘍免疫調節機構及び遺伝子の解析
- Principal Investigator
  
  岡田全司
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Osaka University

All 2012 2011 2010 2009

All Journal Article

[Journal Article] Early[ 18F] fluorodeoxyglucose positron emission tomography at two days of gefitinib treatment predicts clinical outcome in patients with adenocarcinoma of the lung2012
- Author(s)
  Takahashi R, Hirata H, Tachibana I, Shimosegawa E, Inoue A, Nagatomo I, Takeda Y, Kida H, Goya S, Kijima T, Yoshida M, Kumagai T, Kumanogoh A, Okumura M, Hatazawa J, Kawase I.
- Journal Title
  
  Clin Cancer Res
  
  Volume: 18(1) Pages: 220-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590992
[Journal Article] 4-Hydroxy-2-nonenal induces chronic obstructive pulmonary disease-like histopathologic changes in mice2012
- Author(s)
  Takimoto T, Yoshida M, Hirata H, Kashiwa Y, Takeda Y, Goya S, Kijima T, Kumagai T, Tachibana I, Kawase I.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 420(1) Pages: 84-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590992
[Journal Article] Two cases of leptomeningeal metastases from lung adenocarcinoma which progressed during gefitinib therapy but responded to erlotinib2012
- Author(s)
  Tetsumoto S, Osa A, Kijima T, Minami T, Hirata H, Takahashi R, Kuhara H, Nagatomo I, Takeda Y, Kida H, Goya S, Tachibana I, Kawase I.
- Journal Title
  
  Int J Clin Oncol
  
  Volume: 17(2) Pages: 155-9
- NAID
  10030626570
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590992
[Journal Article] Safe and successful treatment with erlotinib after gefitinib-induced hepatotoxicity : difference in metabolism as a possible mechanism2011
- Author(s)
  Takashi Kijima, Tomohito Shimizu, Shinpei Nonen, Mitsugi Furukawa, Yasushi Otani, Toshiyuki Minami, Ryo Takahashi, Haruhiko Hirata, Izumi Nagatomo, Yoshito Takeda, Hiroshi Kida, Sho Goya, Yasushi Fujio, Junichi Azuma, Isao Tachibana, Ichiro Kawase
- Journal Title
  
  J Clin Oncol
  
  Volume: 29(19)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590992
[Journal Article] Involvement of Endothelial Apoptosis Underlying COPD-Like Phenotype in Adiponectin-Null Mice : Implications for Therapy2011
- Author(s)
  Nakanishi K, Takeda Y(equally first author), Tetsumoto S, Iwasaki T, Tsujino K, Kuhara H, Jin Y, Nagatomo I, Kida H, Goya S, Kijima T, Maeda N, Funahashi T, Shimomura I, Tachibana I, Kawase I.
- Journal Title
  
  Am J Respir Crit Care Med
  
  Volume: 183(9) Pages: 1164-75
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590992
[Journal Article] Favorable response to crizotinib in three patients with echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase fusion-type oncogene-positive non-small cell lung cancer2011
- Author(s)
  Kijima T, Takeuchi K, Tetsumoto S, Shimada K, Takahashi R, Hirata H, Nagatomo I, Hoshino S, Takeda Y, Kida H, Goya S, Tachibana I, Kawase I.
- Journal Title
  
  Cancer Sci
  
  Volume: 102(8) Pages: 1602-4
- NAID
  10030242650
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590992
[Journal Article] Cell surface tetraspanin CD9 mediates chemoresistance in small cell lung cancer2010
- Author(s)
  Kohmo S, Kijima T, Otani Y, Mori M, Minami T, Takahashi R, Nagatomo I, Takeda Y, Kida H, Goya S, Yoshida M, Kumagai T, Tachibana I, Yokota S, Kawase I.
- Journal Title
  
  Cancer Res
  
  Volume: 70(20) Pages: 8025-35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590992
[Journal Article] COPDモデルとしてのテトラスパニンCD9/CD81ダブルノックアウトマウスの解析2009
- Author(s)
  武田吉人, 立花功, 川瀬一郎
- Journal Title
  
  International Review of Asthma & COPD 11
  
  Pages: 31-36
- Data Source
  KAKENHI-PROJECT-20590922
[Journal Article] Tetraspanin CD9 negatively regulates lipopolysaccharide-induced macrophage activation and lung inflammation2009
- Author(s)
  Mayumi Suzuki, Isao Tachibana, Yoshito Takeda, Ping He, Seigo Minami, Takeo Iwasaki, Sho Goya, Takashi Kijima, Toru Kumagai, Mitsuhiro Yoshida, Tadashi Osaki, and Ichiro Kawase
- Journal Title
  
  J Immunol
  
  Volume: 182(10) Pages: 6485-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590992
[Journal Article] COPDモデルとしてのテトラスパニンCD9/CD81ダブルノックアウトマウスの解析2009
- Author(s)
  武田吉人, 立花功, 川瀬一郎
- Journal Title
  
  International Review of Asthma & COPD 11
  
  Pages: 31-36
- Data Source
  KAKENHI-PROJECT-21590992

1. 桝野富彌 (20135677)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
2. 岡田全司 (40160684)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. 小倉剛 (00028490)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
4. TACHIBANA Isao (60324761)

# of Collaborated Projects: 3 results

# of Collaborated Products: 10 results
5. TANIO Yoshiro (50197521)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. TAKAHASHI Ryo (10546865)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. TAKEDA Yoshito (40452388)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
8. OSAKI Tadashi (50324778)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. NAKA Tetsuji (30303936)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. INOUE Tamotsu (00203240)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 秋吉毅 (70038660)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 審良静男 (50192919)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 安部真佐子 (30222665)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 林清二 (70218577)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 東純一 (30144463)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 吉田光弘 (90359844)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 藤尾慈 (20359839)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 原秀樹 (10208655)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. SAITO Shinichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KAWASE Ichiro 川瀬 一郎

川瀬 一郎

Research Projects

Research Products

Co-Researchers

Principal Investigator

Project Period (FY)

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Research Institution

Role or tetraspanins in angiogenesis and lymphangiogenesisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Expression of tetraspanins in human lung cancer cells : frequent downregulation of CD9 and its contribution to cell motility in small cell lung cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

Principal Investigator

Project Period (FY)

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Research Institution

アデノウイルスベクターを用いたIL-6遺伝子導入による間質性肺炎モデル動物の作製Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Expression and function of neural cell adhesion molecule (N-CAM) in small cell lung cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Models of immunotherapy using monoclonal antibodies against human small cell lung cancer.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Institution

[Journal Article] Early[ 18F] fluorodeoxyglucose positron emission tomography at two days of gefitinib treatment predicts clinical outcome in patients with adenocarcinoma of the lung2012

Author(s)

Journal Title

Data Source

[Journal Article] 4-Hydroxy-2-nonenal induces chronic obstructive pulmonary disease-like histopathologic changes in mice2012

Author(s)

KAWASE Ichiro 川瀬一郎

川瀬一郎