SUGIHARA Kenichi 杉原健一

… Alternative Names

SUGIHARA KENICHI 杉原健一

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Researcher Number	10171167
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2009: 東京医科歯科大学, 医歯(薬)学総合研究科, 教授 2009: 東京医科歯科大学, 医歯学総合研究科, 教授 2007 – 2009: Tokyo Medical and Dental University, 大学院・医歯学総合研究科, Professor 2005 – 2006: 東京医科歯科大学, 大学院医歯学総合研究科, 教授 2000 – 2005: 東京医科歯科大学, 大学院・医歯学総合研究科, 教授 … More 2003: Tokyo Medical and Dental University, Graduate School Department of physiology, Professor, 大学院・歯学総合研究科, 教授 1997 – 1999: 東京医科歯科大学, 医学部, 教授 1988: 東京大学, 医学部(病), 医員 1988: 東京大学, 医学部, 医員 1988: MEDICAL STAFF.Faculty of Medicine,University of Tokyo, 医学部第一外科, 医員 Less
Review Section/Research Field	Principal Investigator Digestive surgery / Digestive surgery / General surgery Except Principal Investigator Digestive surgery / Digestive surgery / Biological Sciences / General surgery
Keywords	Principal Investigator 大腸癌 / lung metastasis / gastric cancer / colorectal cancer / COX-2 inhibitor / cyclooxygenase / COX-2 / COX2 / COX-2阻害剤 / NSAIDs … More / Cyclooxygenase-2 / 癌 / iver metastasis / COX2阻害剤 / 血行性転移 / k-ras / 大腸発癌 / 肺転移 / 血管鋳型 / 血管新生 / 5-lipoxygenase / cyclooxygenase 2 / angiogenesis / live matastasis / liver metastasis / familial nolyposis coli / Colorectal cancer / colorectal adenoma / COX-2 Inhibitor / NSAID / 大腸腺種 / サイクロオキシゲナーゼ / 治療 / 動物実験 / 大腸腺腫症 / 大腸腺腫 / 大腸線腫症 / 大腸線腫 / CARCINOMA / METASTASIS / LIVER / 肝類洞壁内皮細胞 / 肝転移 / 転移 / 肝 … More Except Principal Investigator 大腸癌 / DYSPLASIA / POLYPLOID / ANEUPLOID / DNA / Tissue Microarray / colorectal cancer / COX-2 / 大腸腺腫 / マイクロアレイ / マイクロRNA / SOX2 / 生活習慣 / メチル化 / 胃がん / ULCERATIVE COLITIS / ADENOMA / DNA PLOIDY PATTERN / DNA定量 / 腺腫内癌 / dysplasia / frat adenoma / Pロチノイド / DYSPLASIA腺腫 / カルチノイド / 潰瘍性大腸炎 / 腺腫 / 核DNA量 / DNA ploidy pattern / cancer-related protein / Recipient block / Array block / Donor block / immunity histology experiment / 癌関連蛋白 / レシピエントブロック / アレイブロック / ドナーブロック / 免疫組織学的実験 / gastric cancer / bipolar scissors / harmonic / cautery / Nerve preserving operation / Laparoscopic surgery / 神経温存 / 腹腔鏡下 / 神経温存手術 / 腹腔鏡下大腸切除 / 腹腔鏡下胃切除 / バイポーラシザーズ / 神経損傷 / 胃癌 / バイポーラ・メス / 超音波凝固切開装置 / 電気メス / 自律神経温存手術 / 腹腔鏡下手術 / colorectal adenoma / Cycooxygenase-2 / cyclooxygenase-2 / proliferating cell nuclear antigen / 十二指腸乳頭部癌 / 十二指腸乳頭部腺腫 / サイクロオキシゲナーゼ / 家族性大腸腺腫症 / cox-2 / non-polypoid cancer / polypoid cancer / Cox2 / Cyclooxygenase-2 / 好中球 / 転移巣形成 / PGE_2局所不活化率 / 局所免疫 / 実験的肝転移モデル / 免疫抑制 / 大腸癌組織におけるPGE_2不活化率 / 大腸癌局所免疫 / 大腸癌肝転移 / プロスタグランジンE_2(PGE_2) / EMT / 癌幹細胞 / 骨髄・末血 / 宿主側ニッチ / 転移・再発 / 消化器癌 / 化学療法 / 抗癌剤感受性 / 予後因子 / リアルタイムPCR / 遺伝子発現 / RT-PCR / パラフィン包埋標本 / 大腸小腸肛門外科学 / エストジェン受容体 / 分化 / カルシュウムチャンネル遺伝子 / トランスジェニックマウス / 緑茶 / ノックアウト / IQGAP2 / NOTCH / 血球DNA / E-カドヘリン / マウスモデル / 実験動物モデル / DNAメチル化 / エピジェネティクス / 癌特異抗原 / ゼノ移植 / 免疫不全マウス / 免疫療法 / hMLH1遺伝子 / 大腸がん / SOX2遺伝子 / 二次原発がん / PDX1遺伝子 / CDX2遺伝子 / 転写因子 / 発生リスク / 生活習慣要因 / PDX1 / 転写調節 / ホメオプロテイン / MUC6 / DNAメチルトランスフェラーゼ / カルシウムチャンネル / BMP-2 / エピジェネティック疫学 / CDX2 / Gastsin Releasing Peptide / ニューロテンシン / ボンベシン / ガストリン / 消化管ホルモン受容体 / エンドセリン受容体 / エンドセリン / 受容体 Less

大規模症例における消化器癌転移メカニズムの網羅的・統合的解析
- Principal Investigator
  
  三森功士
- Project Period (FY)
  2009
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General surgery
- Research Institution
  Kyushu University
Development and clinical application of cDNA microarray using formalin fixed paraffin embedded specimen
- Principal Investigator
  
  UETAKA Hiroyuki (UETAKE Hiroyuki)
- Project Period (FY)
  2006 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Tokyo Medical and Dental University
Relationship between surrogate markers including DNA methylation and lifestyle factors in gastric carcinogenesis
- Principal Investigator
  
  YUASA Yasuhito
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
Cyclooxygenase-2 inhibitor is a possible new drug for treatment of gastrointestinal cancersPrincipal Investigator
- Principal Investigator
  
  SUGIHARA Kenichi
- Project Period (FY)
  2004 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Tokyo Medical and Dental University
γ鎖/RAG2ダブルノックアウトマウスを用いた新しい癌特異的免疫反応評価法の確立
- Principal Investigator
  
  岡部聰
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Tokyo Medical and Dental University
Establishment of evaluation method and influence of the various operative devices for the nerve in a laparoscopic autonomic nerve preserving operation
- Principal Investigator
  
  KOJIMA Kazuyuki
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Tokyo Medical and Dental University
Establishment of diagnostic system by immunohistochemistory using Tissue Microarray for human gastric cancer
- Principal Investigator
  
  YAMADA Hiroyuki, 山下俊樹
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Tokyo Medical and Dental University
宿主・環境要因に着目した消化管がんの二次原発がん発生リスクに関する研究
- Principal Investigator
  
  YUASA Yasuhito
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
Cyclooxygenase-2 in development of colorectal neoplasia and effect of cyclooxyhgenase-2 inhbitor on colorectal neoplasiaPrincipal Investigator
- Principal Investigator
  
  SUGIHARA Kenichi
- Project Period (FY)
  2000 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Tokyo Medical and Dental University
大腸癌における消化管ホルモン受容体発現の検討
- Principal Investigator
  
  YOSHINAGA Keigo
- Project Period (FY)
  1999 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Tokyo Medical and Dental University
Expression and function of cyclooxygenase-2 in human colorectal adenomas and cancers
- Principal Investigator
  
  ENOMOTO Masayuki, 豊岡正裕
- Project Period (FY)
  1999 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Tokyo Medical & Dental University
CORELATION BETWEEN HEPATIC SINUSOIDAL ENDOTHELIAL CELLS AND HUMAN COLORECTAL CARCINOMA CELLS IN LIVER METASTASISPrincipal Investigator
- Principal Investigator
  
  SUGIHARA Kenichi, 東海林豊
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Tokyo Medical and Dental University
大腸癌肝転移の基礎的臨床的研究ーアラキドン酸カスケ-ドからみた転移機講の解明とその臨床応用
- Principal Investigator
  
  森岡恭彦
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  The University of Tokyo
STUDY ON CLASSIFICATION OF GASTROINTESTINAL NEOPLASIA BY DNA PLOIDY PATTERN
- Principal Investigator
  
  MUTO TETSUICHIRO
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Digestive surgery
- Research Institution
  University of Tokyo

All 2009 2008 2007 2006 2005 2004 2003

All Journal Article Presentation Book

[Book] インフォームドコンセントのための図説シリーズ抗悪性腫瘍薬大腸癌(10)CVポート留置について2009
- Author(s)
  植竹宏之, 石川敏昭, 杉原健一
- Total Pages
  108
- Publisher
  医薬ジャーナル
- Data Source
  KAKENHI-PROJECT-18390362
[Book] インフォームドコンセントのための図説シリーズ抗悪性腫瘍薬大腸癌(11)肝動注療法2009
- Author(s)
  植竹宏之, 石川敏昭, 杉原健一
- Total Pages
  108
- Publisher
  医薬ジャーナル
- Data Source
  KAKENHI-PROJECT-18390362
[Book] インフォームドコンセントのための図説シリーズ抗悪性腫瘍薬大腸癌大腸癌の化学療法で用いられる主なレジメン(6)その他の治療法2009
- Author(s)
  植竹宏之, 石川敏昭, 杉原健一
- Total Pages
  108
- Publisher
  医薬ジャーナル
- Data Source
  KAKENHI-PROJECT-18390362
[Book] Cancer treatment navigator2008
- Author(s)
  植竹宏之, 石川敏昭, 杉原健一
- Total Pages
  287
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-18390362
[Book] 期待される選択的COX-2阻害薬選択的COX-2阻害薬のがん化学予防2007
- Author(s)
  樋口哲郎、杉原健一
- Total Pages
  5
- Publisher
  治療学
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390374
[Book] クリニカルオンコロジーガイド消化器癌化学療法 (分担執筆)2007
- Author(s)
  植竹宏之、杉原健一
- Total Pages
  278
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-18390362
[Book] COXinhibitorによる大腸癌のchemoprevention Pharma Medica2005
- Author(s)
  樋口哲郎、杉原健一
- Total Pages
  6
- Publisher
  Pharma Medica
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390374
[Book] 大腸癌の前癌病変とchemoprevention:家族性大腸腺腫症に対するCOX-2阻害薬の効果2005
- Author(s)
  樋口哲郎、杉原健一
- Total Pages
  7
- Publisher
  日本メディカルセンター
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390374
[Book] イラストレーテッド腹腔鏡下胃切除術2005
- Author(s)
  小嶋一幸, 杉原健一
- Total Pages
  108
- Publisher
  医学書院
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591387
[Book] 専門医を目指すための経験すべき鏡視下消化器手術2003
- Author(s)
  小嶋一幸, 杉原健一
- Total Pages
  180
- Publisher
  メジカルビュー社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591387
[Journal Article] 【大腸がん化学療法のNEW STRATEGY】切除不能進行・再発大腸がんに対する化学療法大腸がん化学療法におけるベバシズマブの位置付けとその効果2009
- Author(s)
  植竹宏之, 石川敏昭, 杉原健一
- Journal Title
  
  Mebio 26
  
  Pages: 66-71
- Data Source
  KAKENHI-PROJECT-18390362
[Journal Article] 【大腸癌治療の現在化学療法と外科手術のコンビネーション】病期(ステージ)と大腸癌術後補助化学療法の適応2009
- Author(s)
  植竹宏之, 杉原健一
- Journal Title
  
  Pharma Medica 27
  
  Pages: 11-14
- Data Source
  KAKENHI-PROJECT-18390362
[Journal Article] 【大腸癌治療の現在化学療法と外科手術のコンビネーション】病期 (ステージ) と大腸癌術後補助化学療法の適応2009
- Author(s)
  植竹宏之, 杉原健一
- Journal Title
  
  Pharma Medica 27
  
  Pages: 11-14
- Data Source
  KAKENHI-PROJECT-18390362
[Journal Article] 大腸がん術後補助化学療法における欧米と日本の相違点2009
- Author(s)
  植竹宏之, 石川敏昭, 杉原健一
- Journal Title
  
  臨床腫瘍プラクティス 5
  
  Pages: 305-307
- NAID
  40016795387
- Data Source
  KAKENHI-PROJECT-18390362
[Journal Article] DNA methylation status is inversely correlated with green tea intake and physical activity in gastric cancer patients.2009
- Author(s)
  Yuasa Y, Nagasaki H, Akiyama Y, Hashimoto Y, Takizawa T, Kojima K, Kawano T, Sugihara K, Imai K, Nakachi K
- Journal Title
  
  Int. J. Cancer 124
  
  Pages: 2677-2682
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015013
[Journal Article] Over-and under-expressed microRNAs in human colorectal cancer2009
- Author(s)
  Motoyama K, Inoue H, Takatsuno Y, Tanaka F, Mimori K, Uetake H, Sugihara K, Mori M.
- Journal Title
  
  Int J Oncol 34
  
  Pages: 1069-1075
- Data Source
  KAKENHI-PROJECT-18390362
[Journal Article] 【大腸がん化学療法のNEW STRATEGY】切除不能進行・再発大腸がんに対する化学療法大腸がん化学療法におけるベバシズマブの位置付けとその効果2009
- Author(s)
  植竹宏之, 石川敏昭, 杉原健一
- Journal Title
  
  Mebio
  
  Pages: 66-71
- Data Source
  KAKENHI-PROJECT-18390362
[Journal Article] Efficacy of laser capture microdissection plus RT-PCR technique in analyzing gene expression levels in human gastric cancer and colon cancer2008
- Author(s)
  Makino H, Uetake H, Danenberg K, Danenberg PV, Sugihara K
- Journal Title
  
  BMC Cancer 8
  
  Pages: 210-210
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390362
[Journal Article] Lactate dehydrogenase-5 (LDH-5) expression in human gastric cancer : Association with hypoxia-inducible factor (HIF-1 alpha) pathway, angiogenic factors production and poor prognosis2008
- Author(s)
  Kolev Y, Uetake H, Takagi Y, Sugihara K.
- Journal Title
  
  Ann Surg Oncol 15
  
  Pages: 2336-2344
- Data Source
  KAKENHI-PROJECT-18390362
[Journal Article] Efficacy of laser capture microdissection plus RT-PCR technique in analyzing gene expression levels in human gastric cancer and colon cancer2008
- Author(s)
  Makino H, Uetake H, Danenberg K, Danenberg PV, Sugihara K.
- Journal Title
  
  BMC Cancer 8
  
  Pages: 210-210
- Data Source
  KAKENHI-PROJECT-18390362
[Journal Article] Messenger RNA expression of vascular endothelial growth factor and its receptors in primary colorectal cancer and corresponding liver metastasis.2008
- Author(s)
  Kobayashi H, Sugihara K, Uetake H, Higuchi T, Yasuno M, Enomoto M, Kuramochi H, Lenz HJ, Danenberg KD, Danenberg PV.
- Journal Title
  
  Ann Surg Oncol 15
  
  Pages: 1232-1238
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390362
[Journal Article] Messenger RNA expression of vascular endothelial growth factor and its receptors in primary colorectal cancer and corresponding liver metastasis2008
- Author(s)
  Kobayashi H, Sugihara K, Uetake H, Higuchi T, Yasuno M, Enomoto M, Kuramochi H, Lenz HJ, Danenberg KD, Danenberg PV.
- Journal Title
  
  Ann Surg Oncol 15
  
  Pages: 1232-1238
- Data Source
  KAKENHI-PROJECT-18390362
[Journal Article] Clinical Significance of High Mobility Group A2 in Human Gastric Cancer and Its Relationship to let-7 MicroRNA Family2008
- Author(s)
  Motoyama K, Inoue H, Nakamura Y, Uetake H, Sugihara K, Mori M.
- Journal Title
  
  Clin Cancer Res 14
  
  Pages: 2334-2340
- Data Source
  KAKENHI-PROJECT-18390362
[Journal Article] Clinical Significance of High Mobility Group A2 in Human Gastric Cancer and Its Relationship to let-7 MicroRNA Family.2008
- Author(s)
  Motoyama K, Inoue H, Nakamura Y, Uetake H, Sugihara K, Mori M.
- Journal Title
  
  Clin Cancer Res 14
  
  Pages: 2334-2340
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390362
[Journal Article] The effect of Meloxicam, a selective COX-2 inhibitor, on the microvascularture of small metastatic liver tumors in rats2007
- Author(s)
  Iwasse N, Higuchi T, Gond a T, Kobayashi H, Uetake H, Enomoto M, Sugihara K
- Journal Title
  
  Jpn J CIini Oncol 9
  
  Pages: 673-678
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16390374
[Journal Article] コンセンサス術後補助療法大腸癌2007
- Author(s)
  石川敏昭, 植竹宏之, 杉原健一
- Journal Title
  
  コンセンサス癌治療 6(2)
  
  Pages: 72-75
- Data Source
  KAKENHI-PROJECT-18390362
[Journal Article] Prognostic significance of VEGF expression in correlation with COX-2, microvessel density, and clinicopathological characte ristics in human gastric carcinoma2007
- Author(s)
  Kolev Y, Uetake H, Iida S, Ishikawa T, Kawano T, Sugihara K
- Journal Title
  
  Ann Surg Oncol 14(10)
  
  Pages: 2738-47
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16390374
[Journal Article] 大腸癌化学療法の進歩と限界2007
- Author(s)
  植竹宏之、石川敏昭、杉原健一
- Journal Title
  
  日医会雑誌 136
  
  Pages: 535-538
- Data Source
  KAKENHI-PROJECT-18390362
[Journal Article] The effect of a selective COX-2 inhibitor, Meloxicam, on the microvascularture of small metastatic liver tumors in rats2007
- Author(s)
  Iwase N, Gonda T, Kobayashi H, Uetake H, Enomoto M, Higuchi T, Sugihara K
- Journal Title
  
  Jpn J Clin Oncol (In press)
- Data Source
  KAKENHI-PROJECT-16390374
[Journal Article] 神経障害とその対策2007
- Author(s)
  植竹宏之、石川敏昭、杉原健一
- Journal Title
  
  消化器外科 30
  
  Pages: 1213-1218
- Data Source
  KAKENHI-PROJECT-18390362
[Journal Article] The effect of meloxicam, a selective COX-2 inhibitor, on the microvasculature of small metastatic liver tumors in rats2007
- Author(s)
  Iwase N, Higuchi T, Gonda T, Kobayashi H, Uetake H, Enomoto M, Sugihara K
- Journal Title
  
  Jpn J Clin Oncol. 37(9)
  
  Pages: 673-8
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16390374
[Journal Article] Correlations between cyclooxygenase-2 expression and angiogenic factors in primary tumors and liver metastases in colorectal cancer2007
- Author(s)
  Nakamoto RH, Uetake H, Iida S, Kolev YK, Soumaoro LT, Takagi Y, Yasuno M, Sugihara K
- Journal Title
  
  Jpn J Clin Oncol. 37(9)
  
  Pages: 679-85
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16390374
[Journal Article] 下部消化管疾患における最近の話題大腸癌の化学療法の進歩と限界2007
- Author(s)
  植竹宏之, 石川敏昭, 杉原健一
- Journal Title
  
  日本医師会雑誌 136(3)
  
  Pages: 535-538
- Data Source
  KAKENHI-PROJECT-18390362
[Journal Article] 大腸癌治療に関する最新のデータ2007
- Author(s)
  植竹宏之、榎本雅之、樋口哲郎、安野正道、飯田聡、小林宏寿、石川敏昭、石黒めぐみ、杉原健一
- Journal Title
  
  臨床外科
  
  Pages: 349-353
- Data Source
  KAKENHI-PROJECT-18390362
[Journal Article] The effect of meloxicam, a selective COX-2 inhibitor, on the microvasculature of small metastatic liver tumors in rats2007
- Author(s)
  Iwase N, Higuchi T, Gonda T, Kobayashi H, Uetake H, Enomoto M, Sugihara K.
- Journal Title
  
  Jpn J Clin Oncol 37(9)
  
  Pages: 673-8
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390374
[Journal Article] Prognostic significance of VEGF expression in correlation with COX-2, microvessel density, and clinicopathological characteristics in human gastric carcinoma2007
- Author(s)
  Kolev Y, Uetake H, Iida S, Ishikawa T, Kawano T, Sugihara K.
- Journal Title
  
  Ann Surg Oncol 14(10)
  
  Pages: 2738-47
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390374
[Journal Article] 「癌に対する血管新生阻害薬の臨床効果について教えてください」2007
- Author(s)
  植竹宏之、石川敏昭、杉原健一
- Journal Title
  
  Surgery Frontier
  
  Pages: 113-115
- Data Source
  KAKENHI-PROJECT-18390362
[Journal Article] 侵襲をめぐるQ&A血管新生癌に対する血管新生阻害薬の臨床効果について教えて下さい (Q&A)2007
- Author(s)
  植竹宏之, 石川敏昭, 杉原健一
- Journal Title
  
  Surgery Frontier. 14(4)
  
  Pages: 463-465
- Data Source
  KAKENHI-PROJECT-18390362
[Journal Article] Correlations between cyclooxygenase-2 expression and angiogenic factors in primary tumors and liver metastases in colorectal cancer2007
- Author(s)
  Nakamoto RH, Uetake H, Iida S, Kolev YK, Soumaoro LT, Takagi Y, Yasuno M, Sugihara K.
- Journal Title
  
  Jpn J Clin Oncol 37(9)
  
  Pages: 679-85
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390374
[Journal Article] Prognostic significance of VEGF expression in correlation with COX-2, microvessel density, and clnicopathological characteristics in human gastric carcinoma2007
- Author(s)
  Koler Y, Uetake H, lida S, Ishikawa T, Kawano T, Sugihara K.
- Journal Title
  
  Ann Surg Oncol 10
  
  Pages: 2738-2747
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16390374
[Journal Article] 外科医から見た化学療法時の緊急対応2007
- Author(s)
  植竹宏之、石川敏昭、杉原健一
- Journal Title
  
  医学の歩み
  
  Pages: 1209-1212
- Data Source
  KAKENHI-PROJECT-18390362
[Journal Article] 大腸癌の発生から転移までのメカニズム2007
- Author(s)
  石川敏昭, 植竹宏之, 杉原健一
- Journal Title
  
  薬局 58(5)
  
  Pages: 1855-1860
- Data Source
  KAKENHI-PROJECT-18390362
[Journal Article] Expression of 5-Lipoxygenase in human colorectal cancer2006
- Author(s)
  Soumaoro LT, Iida S, Uetake H, Ishiguro M, Takagi Y, Higuchi T, Yasuno M, Enomoto M, Sugihara K.
- Journal Title
  
  World J Gastroenterol 12(39)
  
  Pages: 6355-6360
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390374
[Journal Article] Coexpression of VEGF-C and Cox-2 in human colorectal cancer and its association with lymph node metastasis2006
- Author(s)
  Soumaoro LT, Uetake H, Takaagi Y, Iida S, Higuchi T, Yasuno M, Enomoto M, Sugihara K
- Journal Title
  
  Diseases of the colon & Rectum 49
  
  Pages: 1-7
- Data Source
  KAKENHI-PROJECT-16390374
[Journal Article] Coexpression of VEGF-C and Cox-2 in Human Colorectal Cancer and its Association With Lymph Node Metastasis2006
- Author(s)
  Soumaoro LT, Uetake H, Takagi Y, Iida S, Higuchi T, Yasuno M, Enomoto M, Sugihara K.
- Journal Title
  
  Dis Colon Rectum 49(3)
  
  Pages: 392-398
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390374
[Journal Article] Coexpression of VEGF-C and Cox-2 in Human Colorectal Cancer and its Association With Lymph Node Metastasis2006
- Author(s)
  Soumaoro LT, Uetake H, Takagi Y, Iida S, Higuchi T, Yasuno M, Enomoto M, Sugihara K
- Journal Title
  
  Dis Colon Rectum 49(3)
  
  Pages: 392-398
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16390374
[Journal Article] Expression of 5-Lipoxygenase in human colorectal cancer2006
- Author(s)
  Soumaoro LT, Iida S, Uetake H, Ishiguro M, Takagi Y, Higuchi T, Yasuno M, Enomoto M, Sugihara K
- Journal Title
  
  World J Gastroenterol 12(39)
  
  Pages: 6355-6360
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16390374
[Journal Article] JTE-522 a selective COX-2 inhibitor, inhibits growth of pulmonary metastases of colorectal cancer in rats2005
- Author(s)
  Kobayashi H, Uetake H, Higuchi T, Enomoto M, Sugihara K
- Journal Title
  
  BMC Cancer 5
  
  Pages: 1471-2407
- Data Source
  KAKENHI-PROJECT-16390374
[Journal Article] Laparoscopy-assisted resection of gastric remnant cancer.2005
- Author(s)
  Yamada H, Kojim K, Yamashita T, Kawano T, Sugihara K, Nihei Z
- Journal Title
  
  Surg Laparosc Endosc Percutan Tech 15(4)
  
  Pages: 226-229
- Data Source
  KAKENHI-PROJECT-15591387
[Journal Article] Laparoscopy-assisted resection of gastric remnant cancer.2005
- Author(s)
  Yamada H, Kojima K, Yamashita T, Kawano T, Sugihara K, Nihei Z
- Journal Title
  
  Surg Laparosc Endosc Percutan Tech 15(4)
  
  Pages: 226-9
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591387
[Journal Article] JTE-522, a selective COX-2 inhibitor, inhibits growth of pulmonary metastases of colorectal cancer in rats2005
- Author(s)
  Kobayasi H, Uetake H, Higuchi T, Enomoto M, Sugihara K
- Journal Title
  
  BMC Cancer 5
  
  Pages: 26-26
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16390374
[Journal Article] Relationship between CDX2 gene methylation and dietary factors in gastric cancer patients.2005
- Author(s)
  Yuasa Y, Nagasaki H, Akiyama Y, Sakai H, Nakajima T, Ohkura Y, Takizawa T, Koike M, Tani M, Iwai T, Sugihara K, Imai K, Nakachi K
- Journal Title
  
  Carcinogenesis 26
  
  Pages: 193-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17015013
[Journal Article] JTE-522, a selective COX-2 inhibitor, inhibits growth of pulmonary metastases of colorectal cancer in rats2005
- Author(s)
  Kobayashi H, Uetake H, Higuchi T, Enomoto M, Sugihara K.
- Journal Title
  
  BMC Cancer 5
  
  Pages: 26-26
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390374
[Journal Article] JTE-522 a selective COX-2 inhibitor, interferes with the growth of lung metastases from colorectal cancer in rats due to inhibition of neovascularization : a vascular cast model study2004
- Author(s)
  Kobayashi H, Gonda T, Uetake H, Higuchi T, Enomoto M, Sugihara K.
- Journal Title
  
  Int J Cancer 112
  
  Pages: 920-926
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390374
[Journal Article] 腹腔鏡下胃切除術の適応と限界2004
- Author(s)
  森田信司, 山下俊樹, 加藤敬二, 山田博之, 小嶋一幸, 河野辰幸, 杉原健一
- Journal Title
  
  癌と化学療法 31巻10号
  
  Pages: 1475-1480
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591387
[Journal Article] JTE-522 a selective COX-2 inhibitor, interferes with growth of lung metastases form colorectal cancer in rats due to inhibition of neovascularization : A vascular cast model study2004
- Author(s)
  Kobayasi H, Uetake H, Sugihara K
- Journal Title
  
  Int J Cancer 112
  
  Pages: 920-926
- Data Source
  KAKENHI-PROJECT-16390374
[Journal Article] Cyclooxygenase-2 overexpression is related to polypoid growth and k-ras gene mutation in T1 colorectal carcinoma2004
- Author(s)
  Okawa T, Yoshinaga K, Uetake H, Sato T, Higuchi T, Nemoto T, Sugihara K.
- Journal Title
  
  Dis Colon Rectum 47(11)
  
  Pages: 1915-1921
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390374
[Journal Article] Cyclooxgenase-2 expression : a significant indicator for patients with colorectal cancer2004
- Author(s)
  Soumaoro LT, Uetake H, Higuchi T, Sugihara K
- Journal Title
  
  Clin Cancer Res 10
  
  Pages: 8465-8471
- Data Source
  KAKENHI-PROJECT-16390374
[Journal Article] Cyclooxygenase-2 expression: a significant prognostic indicator for patients with colorectal cancer2004
- Author(s)
  Soumaoro Labile Togba, Uetake H, Higuchi T, Takagi Y, Enomoto M, Sugihara K
- Journal Title
  
  Clin Cancer Res 10(24)
  
  Pages: 8465-71
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16390374
[Journal Article] Cyclooxygenase-2 expression : a significant prognostic indicator for patients with colorectal cancer2004
- Author(s)
  Soumaoro Labile Togba, Uetake H, Higuchi T, Takagi Y, Enomoto M, Sugihara K.
- Journal Title
  
  Clin Cancer Res 10(24)
  
  Pages: 8465-71
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390374
[Journal Article] JTE-522 a selective COX-2 inhibitor, interferes with the growth of lung metastases from colorectal cancer in rats due to inhibition of neovascularization: a vascular cast model study2004
- Author(s)
  Kobayashi H, Gonda T, Uetake H, Higuchi T, Enomoto M, Sugihara K
- Journal Title
  
  Int J Cancer 112
  
  Pages: 920-926
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16390374
[Journal Article] 家族性大腸腺腫症患者の直腸病変に対するCOX-2選択的阻害剤rofecoxibによる二重盲検比較試験2004
- Author(s)
  樋口哲郎、杉原健一
- Journal Title
  
  消化器外科 38(6)
  
  Pages: 556-562
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16390374
[Journal Article] Cyclooxygenase-2 overexpression is related to polypoid growth and k-ras gene mutation in T1 colorectal carcinoma2004
- Author(s)
  Okawa T, Yoshinaga K, Uetake H, Sato T, Higuchi T, Nemoto T, Sugihara K
- Journal Title
  
  Dis Colon Rectum 47(11)
  
  Pages: 1915-1921
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16390374
[Presentation] Quantitative analysis of genes using FFPE sample was dependent to dilution of a formalin solution and soaking duration : A report of the SACURA Study Group2009
- Author(s)
  Hiroyuki Uetake, Toshiaki Ishikawa, Hideki Ueno, Kenichi Sugihara, Naohiro Tomita
- Organizer
  The 101st annual meeting of AACR
- Place of Presentation
  Denver, Colorado, USA
- Year and Date
  2009-04-21
- Data Source
  KAKENHI-PROJECT-18390362
[Presentation] 大腸癌肝転移に対するBevacizumab併用化学療法後肝切除の有用性2009
- Author(s)
  植竹宏之, 石川敏昭, 光法雄介, 有井滋樹, 杉原健一
- Organizer
  第17回日本消化器関連学会週間
- Place of Presentation
  京都
- Year and Date
  2009-10-16
- Data Source
  KAKENHI-PROJECT-18390362
[Presentation] 大腸癌肝転移に対する Bevacizumab 併用化学療法後肝切除の有用性2009
- Author(s)
  植竹宏之, 石川敏昭, 光法雄介, 有井滋樹, 杉原健一
- Organizer
  第17回日本消化器関連学会週間
- Place of Presentation
  京都
- Year and Date
  2009-10-16
- Data Source
  KAKENHI-PROJECT-18390362
[Presentation] 大腸癌肝転移に対するBevacizumab併用化学療法後肝切除の有用性2009
- Author(s)
  植竹宏之, 石川敏昭, 光法雄介, 有井滋樹, 杉原健一
- Organizer
  第42回制癌剤適応研究会
- Place of Presentation
  東京
- Year and Date
  2009-02-20
- Data Source
  KAKENHI-PROJECT-18390362
[Presentation] Promoter hypermethylation of BNIP3 was correlated to poor prognosis in colorectal cancer patients2008
- Author(s)
  Hiroyuki Uetake, Satoru Iida, Toshiaki Ishikawa, Sayaka Shimizu, Megumi Ishiguro, Kenichi Sugihara
- Organizer
  AACR Annual Meeting
- Place of Presentation
  San Diego, CA
- Year and Date
  2008-04-16
- Data Source
  KAKENHI-PROJECT-18390362
[Presentation] Promoter hypermethylation of BNIP3 was correlated to poor prognosis in human colorectal cancer.2008
- Author(s)
  Hiroyuki Uetake, Satoru Iida, Toshiaki Ishikawa, Sayaka Shimizu, Megumi Ishiguro, Kenichi Sugihara.
- Organizer
  ASCO Annual Meeting
- Place of Presentation
  McCormick Place, Chicago, Illinois
- Year and Date
  2008-05-30
- Data Source
  KAKENHI-PROJECT-18390362
[Presentation] Danenberg^1Molecular Signatures of Gastric Cancers Derived from Microarray Analysis of Paraffin-Embedded Specimens Predict the Degree of Response to CPT11/S-1 Chemotherapy2008
- Author(s)
  Shinji Morita, Mikito Inokuchi, Hiroyuki Uetake, Andreas C. Hoffmann, Janine Cooc, Akiko Omori, Kenichi Sugihara, Kathleen D. Danenberg, Peter V.
- Organizer
  The annual meeting of ASCO
- Place of Presentation
  Chicago, IL, USA
- Year and Date
  2008-06-01
- Data Source
  KAKENHI-PROJECT-18390362
[Presentation] Microarray analysis using paraffin embedded samples of gastric cancer.2007
- Author(s)
  Uetake H, Inokuchi M, Yamashita T, Danenberg K, Danenberg P, Sugihara K.
- Organizer
  ASCO 2007 Annual Meeting (Poster)
- Place of Presentation
  Chicago
- Year and Date
  2007-06-01
- Data Source
  KAKENHI-PROJECT-18390362
[Presentation] 大腸癌原発巣と肝転移巣における血管新生関連遺伝子の発現Laser capture microdissection および real-time RT-PCRによる検討2007
- Author(s)
  小林宏寿、植竹宏之、樋口哲郎、飯田聡、安野正道、榎本雅之、Kathleen Danenberg、Peter Danenberg、杉原健一
- Organizer
  サージカルフォーラム第107回日本外科学会定期学術集会
- Place of Presentation
  大阪
- Year and Date
  2007-04-11
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390374
[Presentation] 消化器癌における抗癌剤感受性因子と遺伝子および遺伝子発現解析法の工夫2007
- Author(s)
  植竹宏之、飯田聡、石川敏昭、Peter Danenberg, Kathleen Danenberg、井ノ口幹人、杉原健一
- Organizer
  第107回日本外科学会定期学術集会(ワークショップ)
- Place of Presentation
  大阪
- Year and Date
  2007-04-13
- Data Source
  KAKENHI-PROJECT-18390362
[Presentation] Positive correlation of angiogenetic factors between primary tumor and liver metastasis in human colorectal cancer.2007
- Author(s)
  Uetake H, Nakamoto RH, Kolev YV, Soumaoro LT, Yasuno M, Iida S, Sugihara K
- Organizer
  AACR Annual Meeting 2007(Poster)
- Place of Presentation
  Los Angeles
- Year and Date
  2007-04-16
- Data Source
  KAKENHI-PROJECT-18390362
[Presentation] 大腸癌原発巣と肝転移巣における各種血管新生因子の発現量の相関2007
- Author(s)
  植竹宏之、Nakamoto Regina、安野正道、杉原健一
- Organizer
  第62回日本消化器外科学会定期学術総会(口演)
- Place of Presentation
  東京
- Year and Date
  2007-07-18
- Data Source
  KAKENHI-PROJECT-18390362
[Presentation] 胃癌におけるCOX-2、VEGF発現について2005
- Author(s)
  コレヴヤニスラヴベルチェヴ、スマオロラビレトーバ、中本レジナ弘美、飯田聡、高木洋子、植竹宏之、杉原健一
- Organizer
  第64回日本癌学会学術総会
- Place of Presentation
  札幌
- Year and Date
  2005-09-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390374
[Presentation] 大腸癌におけるCOX-2、VEGF発現について2005
- Author(s)
  中本レジナ弘美、スマオロラビレトーバ、コレヴヤニスラヴベルチェヴ、安野正道、植竹宏之、飯田聡、杉原健一
- Organizer
  第64回日本癌学会学術総会
- Place of Presentation
  札幌
- Year and Date
  2005-09-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390374
[Presentation] Expression of 5-Lox in the adenoma-carcinoma sequence during colorectal cancer progression2004
- Author(s)
  Soumaoro LT, Nakamoto HR, Uetake H, Takagi Y, Sugihara K
- Organizer
  50th Annual Congress of the Japanese Section of the Intl. College of Surgeon.
- Place of Presentation
  Kurume
- Year and Date
  2004-06-19
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390374
[Presentation] The effect of JTE-522, a selective COX-2 inhibitor, on microvasculature of pulmonary metastasis from colorectal cancer in rats : A vascular cast model study2004
- Author(s)
  Kobayashi H, Uetake H, Higuchi T, Enomoto M, Sugihara K.
- Organizer
  95th Annual Meeting of American Association for Cancer Research
- Place of Presentation
  USA, Orlando.
- Year and Date
  2004-03-30
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390374
[Presentation] The effect of JTE-522, a selective COX-2 inhibitor, on micr ovasculature of pulmonary metastasis from colorectal cancer in rats: A vascular cast model study2004
- Author(s)
  Kobayashi H, Uetake H, Higuchi T, Enomoto M, Sugihara K
- Organizer
  95th Annual Meeting of American Associ ation for Cancer Research
- Place of Presentation
  Orlando, USA
- Year and Date
  2004-03-30
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390374
[Presentation] Co-expression of VEGF-C and Cox-2 in human colorectal carcinoma : correlation with lymph node metastasis and prognosis2004
- Author(s)
  Nakamoto HR, Soumaoro LT, Uetake H, Takagi Y, Sugihara K.
- Organizer
  50th Annual Congress of the Japanese Section of the Intl. College of Surgeon
- Place of Presentation
  Kurume
- Year and Date
  2004-06-19
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390374
[Presentation] Co-expression of VEGF-C and Cox-2 in human colorectal carcinoma: correlatlon with lymph node metastasis and prognosis2004
- Author(s)
  Souinaoro LT, Uetake H, Takagi Y, Sugihara K
- Organizer
  第42回日本癌治療学会
- Place of Presentation
  京都
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390374
[Presentation] Expression of 5-Lox in the adenoma-carcinoma sequence during colorectal cancer progression2004
- Author(s)
  Soumaoro LT, Nakamoto HR, Uetake H, Takagi Y, Sugihara K.
- Organizer
  50th Annual Congress of the Japanese Section of the Intl. College of Surgeon
- Place of Presentation
  Kurume
- Year and Date
  2004-06-19
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390374
[Presentation] Co-expression of VEGF-C and Cox-2 in human colorectal carcinoma: correlation with lymph node metastasis and prognosis2004
- Author(s)
  Nakamoto HR, Soumaoro LT, Uetake H, Takagi Y, Sugihara K
- Organizer
  50th Annual Congress of the Japanese Section of the Intl College of Surgeon.
- Place of Presentation
  Kurume
- Year and Date
  2004-06-19
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390374
[Presentation] Significance of 5-Lox expression in human colorectal neoplasms2004
- Author(s)
  Soumaoro LT, Uetake H, Takagi Y, Sugihara K
- Organizer
  19th World Congress of Intl. Society for Digestive Surgery
- Place of Presentation
  Yokohama
- Year and Date
  2004-11-08
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390374
[Presentation] 大腸癌原発巣と転移巣におけるCyclooxygenase-1および2発現の差異2004
- Author(s)
  植竹宏之、スマオロラビレトーバ、杉原健一
- Organizer
  第63回日本癌学会総会
- Place of Presentation
  福岡
- Year and Date
  2004-09-30
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390374

1. UETAKA Hiroyuki (60311651)

# of Collaborated Projects: 5 results

# of Collaborated Products: 75 results
2. ENOMOTO Masayuki (60301165)

# of Collaborated Projects: 5 results

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SUGIHARA Kenichi 杉原 健一

SUGIHARA KENICHI 杉原 健一

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Cyclooxygenase-2 inhibitor is a possible new drug for treatment of gastrointestinal cancersPrincipal Investigator

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Cyclooxygenase-2 in development of colorectal neoplasia and effect of cyclooxyhgenase-2 inhbitor on colorectal neoplasiaPrincipal Investigator

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CORELATION BETWEEN HEPATIC SINUSOIDAL ENDOTHELIAL CELLS AND HUMAN COLORECTAL CARCINOMA CELLS IN LIVER METASTASISPrincipal Investigator

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[Book] インフォームドコンセントのための図説シリーズ 抗悪性腫瘍薬 大腸癌(10)CVポート留置について2009

Author(s)

SUGIHARA Kenichi 杉原健一

SUGIHARA KENICHI 杉原健一

[Book] インフォームドコンセントのための図説シリーズ抗悪性腫瘍薬大腸癌(10)CVポート留置について2009

[Book] インフォームドコンセントのための図説シリーズ抗悪性腫瘍薬大腸癌(11)肝動注療法2009

[Book] インフォームドコンセントのための図説シリーズ抗悪性腫瘍薬大腸癌大腸癌の化学療法で用いられる主なレジメン(6)その他の治療法2009

[Book] 期待される選択的COX-2阻害薬選択的COX-2阻害薬のがん化学予防2007

[Book] クリニカルオンコロジーガイド消化器癌化学療法 (分担執筆)2007

[Journal Article] 【大腸がん化学療法のNEW STRATEGY】切除不能進行・再発大腸がんに対する化学療法大腸がん化学療法におけるベバシズマブの位置付けとその効果2009

[Journal Article] 【大腸癌治療の現在化学療法と外科手術のコンビネーション】病期(ステージ)と大腸癌術後補助化学療法の適応2009