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KUBO Tai  久保 泰

… Alternative Names

KUBO TAI  久保 泰

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Researcher Number 10178030
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-6404-8295
Affiliation (based on the past Project Information) *help 2020 – 2021: 東京大学, 大学院新領域創成科学研究科, 特任研究員
2019: 国立研究開発法人産業技術総合研究所, 生命工学領域, 招聘研究員
2018: 国立研究開発法人産業技術総合研究所, 創薬プロファイリング研究センター, 副研究センター長
2017 – 2018: 国立研究開発法人産業技術総合研究所, 生命工学領域, 副研究センター長
2016: 国立研究開発法人産業技術総合研究所, その他部局等, 研究員 … More
2015 – 2016: 国立研究開発法人産業技術総合研究所, 創薬プロファイリング研究センター, 副研究センター長
2015 – 2016: 国立研究開発法人産業技術総合研究所, 創薬分子プロファイリング研究センター, 副研究センター長
2015: 国立研究開発法人産業技術総合研究所, 創薬分子プロファイリング研究センター, 副センター長
2014: 独立行政法人産業技術総合研究所, 創薬プロファイリング研究センター, 副研究センター長
2014: 独立行政法人産業技術総合研究所, 創薬分子プロファイリング研究センター, 副研究センター長
2013: 独立行政法人産業技術総合研究所, 創薬分子プロファイリング研究センター, 副センター長
2010 – 2012: 独立行政法人産業技術総合研究所, バイオメディカル研究部門, 主任研究員
2007: 独立行政法人産業技術総合研究所, 脳神経情報研究部門, 研究グループ長
2007: National Institute of Advanced Industrial Science and Technology, Group leader
2006: 独立行政法人産業技術総合研究所, 脳神経研究部門, 研究グループリーダー
1995: (財)国際高等研究所, 研究部, 研究員
1994 – 1995: 財団法人 国際高等研究所, 研究部, 研究員
1987 – 1988: Kyoto University,Faculty of Medicine, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Basic Section 48040:Medical biochemistry-related / Neuroscience in general / Chemical biology
Except Principal Investigator
Tumor therapeutics / Nanomaterials/Nanobioscience / Science and Engineering / Chemical biology / ケミカルバイオロジー
Keywords
Principal Investigator
cDNA / 遷移状態 / 分子動態 / 進化工学 / アセチルコリン受容体 / アロステリック / Aplysia / K+ CHANNEL / 分子生物学 / 中枢神経系 … More / 内向整流性K^+チャネル / ATP依存性K^+チャネル / セロトニン感受性K^+チャネル / アメフラシ / K^+チャネル / 有機ナノチューブ / 分子進化 / 生理活性ペプチド / リフォールディング / マイクロ環境 / 試験管内進化 … More
Except Principal Investigator
パッチクランプ法 / cDNA発現 / ムスカリン性アセチルコリン受容体 / Na^+チャンネル / ニコチン性アセチルコリン受容体 / 免疫療法 / 免疫チェックポイント阻害剤 / がん免疫療法 / 試験管内進化技術 / 合成ペプチド / 小麦胚芽蛋白合成系 / 3-finger protein / PD-1 / Excitation-contraction coupling / Site-directed mutagenesis / cDNA expression / Muscarinic acetylcholine receptor / Ca^<2+> release channel / Ca^<2+> channel / Na^+ channel / Nicotinic acetylcholine receptor / ムスカリン性アセチルコリン受容体サブタイプ / E-C coupling / 電位感受機構 / K^+チャンネル / cGMP-gatedチャンネル / Ca^<2+> releaseチャンネル / グルタミン酸受容体 / 部位特異的変異 / 興奮収縮連関 / 静位特異的変異 / Ca^<2+>放出チャンネル / Ca^<2+>チャンネル / cDNA Cloning / Ionic Channel / Neurotransmitter Receptor / Muscarinic Acetylcholine Receptor / Receptor for Calcium Channel Blockers / Sodium Channel / Nicotinic Acetylcholine Receptor / single-channel recording / 変異受容体 / εサブユニット / Naチャンネル / site-directed mutagenesis / CDNA発現 / CDNAクローニング / cDNAクローニング / イオンチャンネル / 神経伝達物質受容体 / Ca^<2+>チャンネルブロッカー受容体 / bicelles / membrane proteins / lipid bilayers / photolithography / patterning / model membrane / cellular membrane / biological membrane / タンパク質チップ / 人工生体膜 / バイセル / 膜タンパク質 / 脂質二分子膜 / 光リソグラフィー / パターン化 / 人工細胞膜 / 細胞膜 / 生体膜 / 1分子 / 中性子 / バイオ計測 / X線1分子追跡法 / 蛋白質構造動態 / 新規計測手段 / 1分子動態情報 / 局部構造 / X線 / バイオテクノロジー / X線1分子追跡法 / 3次元分子内部動態情報 / X線1分子計測 / 価数変化 / 蛍光X線ホログラフィー / 結晶化 / タンパク質分子 / 標識・無標識法 / X線1分子追跡法 / 蛍光X線ホログラフィー / パドルキメラ / パッチクランプ / 進化分子工学 / 電位センサー / イオンチャネル / ICK / 大腸菌 / 電気生理 / PERISS法 / カルシウムチャネル / ペプチド / トランスクリプトーム / cDNAライブラリー / スキャフォールド / 次世代シーケンス / 毒液 / トランスクリプトーム解析 / 生理活性ペプチド / 毒腺 / タランチュラ Less
  • Research Projects

    (10 results)
  • Research Products

    (43 results)
  • Co-Researchers

    (20 People)
  •  Allosteric modulators that recognize the transition-states of receptor channelsPrincipal Investigator

    • Principal Investigator
      Kubo Tai
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 48040:Medical biochemistry-related
    • Research Institution
      The University of Tokyo
      National Institute of Advanced Industrial Science and Technology
  •  Discovery research of medium molecule drugs for cancer immunotherapy using in vitro molecular evolution technology

    • Principal Investigator
      HEIKE Yuji
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Tumor therapeutics
    • Research Institution
      St. Luke's International University
  •  3D Active Site Science in Biology

    • Principal Investigator
      Sasaki Yuji
    • Project Period (FY)
      2014 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Science and Engineering
    • Research Institution
      The University of Tokyo
  •  Utilization of microenvironment of nanotubes in in-vitro evolutionPrincipal Investigator

    • Principal Investigator
      Kubo Tai
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Chemical biology
    • Research Institution
      National Institute of Advanced Industrial Science and Technology
  •  Peptide drug discovery to identify the calcium channel subfamily by molecular evolutional technique

    • Principal Investigator
      Kimura Tadashi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Chemical biology
    • Research Institution
      National Institute of Advanced Industrial Science and Technology
  •  Search and analysis of bioactive peptides from a spider venom gland

    • Principal Investigator
      KIMURA Tadashi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      ケミカルバイオロジー
    • Research Institution
      National Institute of Advanced Industrial Science and Technology
  •  Development of integrated model biological membranes on solid substrates

    • Principal Investigator
      MORIGAKI Kenichi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Nanomaterials/Nanobioscience
    • Research Institution
      National Institute of Advanced Industrial Science and Technology
  •  STRUCTURE AND FUNCTION ANALYSIS OF ATP-DEPENDENT K+CHANNEL AND SEROTONIN-SENSITIVE K+CHANNELPrincipal Investigator

    • Principal Investigator
      KUBO Tai
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Neuroscience in general
    • Research Institution
      INTERNATIONAL INSTITUTE FOR ADVANCED STUDIES
  •  Studies on the structure and function of neurotransmitter receptors and ionic channels

    • Principal Investigator
      NUMA Shosaku
    • Project Period (FY)
      1988 – 1991
    • Research Category
      Grant-in-Aid for Specially Promoted Research
    • Research Institution
      Kyoto University
  •  Studies on the Structure,Function and Gene Expression of Acetylcholine Receptors

    • Principal Investigator
      NUMA SHOSAKU
    • Project Period (FY)
      1983 – 1987
    • Research Category
      Grant-in-Aid for Specially Promoted Research
    • Research Institution
      Kyoto University

All 2021 2020 2019 2018 2017 2016 2015 2014 2012 Other

All Journal Article Presentation Patent

  • [Journal Article] Living-Cell Diffracted X-ray Tracking Analysis Confirmed Internal Salt Bridge Is Critical for Ligand-Induced Twisting Motion of Serotonin Receptors2021

    • Author(s)
      Mio Kazuhiro、Fujimura Shoko、Ishihara Masaki、Kuramochi Masahiro、Sekiguchi Hiroshi、Kubo Tai、Sasaki Yuji C.
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 22 Issue: 10 Pages: 5285-5285

    • DOI

      10.3390/ijms22105285

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06945, KAKENHI-PUBLICLY-20H04660, KAKENHI-PUBLICLY-20H04696, KAKENHI-PROJECT-21K14466
  • [Journal Article] X-ray-based living-cell motion analysis of individual serotonin receptors2020

    • Author(s)
      Mio Kazuhiro、Ishihara Masaki、Fujimura Shoko、Sasaki Daisuke、Nozawa Shunsuke、Ichiyanagi Kohei、Fukaya Ryo、Adachi Shin-ichi、Kuramochi Masahiro、Sekiguchi Hiroshi、Kubo Tai、Sasaki Yuji C.
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 529 Issue: 2 Pages: 306-313

    • DOI

      10.1016/j.bbrc.2020.05.200

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06945, KAKENHI-ORGANIZER-17H06433, KAKENHI-PLANNED-17H06438, KAKENHI-PUBLICLY-20H04696, KAKENHI-PROJECT-17H06141, KAKENHI-PROJECT-19K15787, KAKENHI-PUBLICLY-20H04660
  • [Journal Article] Agonist and Antagonist-Diverted Twisting Motions of a Single TRPV1 Channel2020

    • Author(s)
      Fujimura Shoko、Mio Kazuhiro、Kuramochi Masahiro、Sekiguchi Hiroshi、Ikezaki Keigo、Mio Muneyo、Hengphasatporn Kowit、Shigeta Yasuteru、Kubo Tai、Sasaki Yuji C.
    • Journal Title

      The Journal of Physical Chemistry B

      Volume: 124 Issue: 51 Pages: 11617-11624

    • DOI

      10.1021/acs.jpcb.0c08250

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06945, KAKENHI-PUBLICLY-20H04696, KAKENHI-PUBLICLY-20H05497, KAKENHI-PROJECT-19K15787, KAKENHI-PUBLICLY-20H04660
  • [Journal Article] cDNA Display of Disulfide-containing Peptide Library and in vitro Evolution2020

    • Author(s)
      Kubo, T., & Naimuddin, M.
    • Journal Title

      Methods in Molecular Biology

      Volume: 2070 Pages: 57-67

    • DOI

      10.1007/978-1-4939-9853-1_4

    • ISBN
      9781493998524, 9781493998531
    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06945
  • [Journal Article] Toward understanding of internal motion measurement with quantum probe and cryo-EM2019

    • Author(s)
      Mio, K.,Fujimura, A.,Kuramochi, M.,Ishihara, M.,Honda, M.,Kubo, T.,Sekiguchi, H.,Sasaki, Y.C.
    • Journal Title

      Japanese Journal of Pesticide Science

      Volume: 44 Issue: 2 Pages: 210-215

    • DOI

      10.1584/jpestics.W19-40

    • NAID

      130007843643

    • ISSN
      2187-0365, 2187-8692
    • Year and Date
      2019-08-20
    • Language
      Japanese
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06945
  • [Journal Article] cDNA Display of Disulfide-containing Peptide Library and in vitro Evolution2019

    • Author(s)
      Kubo, T., & Naimuddin, M
    • Journal Title

      Methods in Molecular Biology

      Volume: 印刷中

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06945
  • [Journal Article] Diffracted X-ray blinking tracks single protein motions2018

    • Author(s)
      Sekiguchi, H., Kuramochi, M., Ikesaki, K., Okamura, Y., Yoshimura, K., Matsubara, K., Chang, J. W., Ohta, N., Kubo, T., Mio, K., Suzuki, Y., Chavas, L. M., & Sasaki, Y.
    • Journal Title

      Scientific Reports

      Volume: 8 Issue: 1 Pages: 1709-1709

    • DOI

      10.1038/s41598-018-35468-3

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06945, KAKENHI-PUBLICLY-17H05539, KAKENHI-PLANNED-26105005, KAKENHI-INTERNATIONAL-15K21719
  • [Journal Article] Modulated dynamics of PAM-α7 nAChR from X-ray single molecular observations2017

    • Author(s)
      Tomoyuki Baba, Tai Kubo, Sumiko Ohashi, Keigo Ikezaki, Kazuhiro Mio, Hiroshi Sekiguchi, Yuji, C. Sasaki
    • Journal Title

      BIOPHYSICAL JOURNAL

      Volume: 112-3 Pages: 327-327

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26350978
  • [Journal Article] A high performance platform based on cDNA display for efficient synthesis of protein fusions and accelerated directed evolution2016

    • Author(s)
      Naimuddin, M., & Kubo, T.
    • Journal Title

      ACS Combinatorial Sci.

      Volume: 18 Issue: 2 Pages: 117-129

    • DOI

      10.1021/acscombsci.5b00139

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26350978, KAKENHI-INTERNATIONAL-15K21719
  • [Journal Article] Random Peptide Library for Ligand and Drug Discovery2016

    • Author(s)
      Tai Kubo
    • Journal Title

      Toxins and Drug Discovery

      Volume: - Pages: 1-24

    • DOI

      10.1007/978-94-007-6726-3_2-1

    • ISBN
      9789400767263
    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26350978
  • [Journal Article] Pr-SNTX, a short-chain three-finger toxin from Papuan pigmy mulga snake, is an antagonist of muscle-type nicotinic acetylcholine receptor (alpha2 beta delta epsilon)2016

    • Author(s)
      Yamauchi, Y., Kimoto, H., Yang, X., Filkin, S., Utkin, Y., Kubo, T., & Inagaki, H.
    • Journal Title

      Biosci. Biotech. and Biochem

      Volume: 80 Issue: 1 Pages: 158-161

    • DOI

      10.1080/09168451.2015.1065169

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26350978
  • [Journal Article] Peptidome and transcriptome analysis of the toxin-like peptides in the venom glands of Tarantula Grammostora rosea2015

    • Author(s)
      Kimura, T., & Kubo, T.
    • Journal Title

      Spider Venoms

      Volume: - Pages: 251-270

    • DOI

      10.1007/978-94-007-6646-4_13-1

    • ISBN
      9789400766464
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26350978, KAKENHI-ORGANIZER-26105001, KAKENHI-INTERNATIONAL-15K21719
  • [Journal Article] Real time ligand-induced motion mappings of AChBP and nAChR using X-ray single molecule tracking2014

    • Author(s)
      Sekiguchi, H., Suzuki, Y., Nishino, Y., Kobayashi, S., Shimoyama, Y., Cai, W., Nagata, K., Okada, M., Ichiyanagi, K., Ohta, N., Yagi, N., Miyazawa*, A., Kubo, T.*, & Sasaki, Y.*
    • Journal Title

      Scientific Reports,

      Volume: - Issue: 1

    • DOI

      10.1038/srep06384

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26350978
  • [Journal Article] Versatile C-terminal specific biotinylation of proteins using both a puromycin-linker and a cell-free translation system for studying high-throughput protein-molecule interactions2014

    • Author(s)
      Nemoto N, Fukushima T, Kumachi S, Suzuki M, Nishigaki K, Kubo T.
    • Journal Title

      Anal Chem.

      Volume: 86 Issue: 17 Pages: 8535-8540

    • DOI

      10.1021/ac501601g

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-25104503, KAKENHI-PROJECT-26350978
  • [Journal Article] Directed evolution of three-finger toxin to produce serine protease inhibitors2014

    • Author(s)
      Cai, W., Naimuddin, M., Inagaki, H., Kameyama, K., Ishida, N., & Kubo, T.*
    • Journal Title

      J. Receptors and Signal Transduction

      Volume: 34 Pages: 154-161

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26350978
  • [Journal Article] Molecular Cloning and Sequence Analysis of the cDNAs Encoding Toxin-Like Peptides from the Venom Glands of Tarantula Grammostola rosea2012

    • Author(s)
      Tadashi Kimura, Seigo Ono and Tai Kubo
    • Journal Title

      International journal of peptides

      Volume: Vol. 2012 Pages: 731293-731293

    • DOI

      10.1155/2012/731293

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22603016
  • [Patent] 生理活性を持つ中分子の薬物動態を改善する方法、薬物動態の改善を利用した中分子ライブラリの製造法2019

    • Inventor(s)
      竹内恒、夏目徹、久保泰
    • Industrial Property Rights Holder
      産業技術総合研究所
    • Industrial Property Rights Type
      特許
    • Filing Date
      2019
    • Overseas
    • Data Source
      KAKENHI-PROJECT-18K06945
  • [Patent] 核酸リンカー2018

    • Inventor(s)
      久保泰、M.ナイムディン
    • Industrial Property Rights Holder
      産業技術総合研究所
    • Industrial Property Rights Type
      特許
    • Filing Date
      2018
    • Acquisition Date
      2019
    • Data Source
      KAKENHI-PROJECT-18K06945
  • [Presentation] ANTAGONIST-INDUCED CLOCKWISE ROTATION IN THE TRPV12019

    • Author(s)
      Shoko Fujimura, Kazuhiro Mio, Masahiro Kuramochi, Hiroshi Sekiguchi, Muneyo Mio, Tai Kubo, Yuji C. Sasaki
    • Organizer
      63rd annual meeting Biophysical Society (BPS19)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06945
  • [Presentation] TRPV1 チャネルの 1 分子内回転動態の決定 Rotational Motions of Single TRPV1 Channel upon Gating2019

    • Author(s)
      三尾 和弘、藤村 章子、倉持 昌弘、関口 博史、三尾 宗代、久保 泰、佐々木 裕次
    • Organizer
      第19回日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-18K06945
  • [Presentation] X線1分子追跡法によるTRPV1チャネルの3次元運動2018

    • Author(s)
      藤村 章子、三尾 和弘、倉持 昌弘、関口博史、池﨑 圭吾、三尾 宗代、久保 泰、佐々木 裕次
    • Organizer
      第27回 日本バイオイメージング学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K06945
  • [Presentation] 3D motion of TRPV1 cation channel depicted by diffracted X-ray tracking method2018

    • Author(s)
      藤村 章子、三尾 和弘、倉 持 昌弘、関口博史、池﨑 圭吾、三尾 宗代、久保 泰、佐々木 裕次
    • Organizer
      日本生物物理 学会第56回年会
    • Data Source
      KAKENHI-PROJECT-18K06945
  • [Presentation] Rotational Brownian Motion of TRPV1 Channel observed by Synchrotron Diffracted X-ray Tracking and Labora tory X-ray blinking analysi2018

    • Author(s)
      三尾 和弘、倉持 昌弘、松原賢、池﨑 圭吾、関口 博史、三尾 宗代、久保 泰、佐々木 裕次
    • Organizer
      62th Annual Meeting Biophysical Society
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06945
  • [Presentation] Screening and characterization of allosteric modulators for nAChR α7 from structurally constrained pept ide librarie2018

    • Author(s)
      久保 泰、伊藤 弘幸、大橋 澄子、齋藤 光義
    • Organizer
      10th International Peptide Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06945
  • [Presentation] Modulated dynamics of PAM-α7 nAChR from X-ray single molecular observations2017

    • Author(s)
      Tomoyuki Baba, Tai Kubo, Sumiko Ohashi, Keigo Ikezaki, Kazuhiro Mio, Hiroshi Sekiguchi, Yuji C. Sasaki
    • Organizer
      Biophysical Society 61st Annual Meeting
    • Place of Presentation
      New Orleans Ernest N. Morial Convention Center(米国ルイジアナ州ニューオリンズ)
    • Year and Date
      2017-02-14
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26350978
  • [Presentation] Development of peptide neurotoxin-based allosteric modulators of nicotinic acetylcholine receptor alpha 7: evaluation by diffracted x-ray tracking method2016

    • Author(s)
      Tai Kubo, Tomoyuki Baba, Sumiko Ohashi, Keigo Ikezaki, Hiroshi Sekiguchi, Yuji C. Sasaki
    • Organizer
      XII Congress of the Pan-America Section of the IST
    • Place of Presentation
      Deauville Hotel(米国フロリダ州マイアミ)
    • Year and Date
      2016-09-18
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26350978
  • [Presentation] リンカー設計およびタンパク質翻訳過程の至適化による試験管内進化技術(cDNAディスプレイ法)の改良と抗VEGF-3本指ペプチドの創製2016

    • Author(s)
      久保泰、Naimuddin Mohammed、多田耕平、大橋澄子、平家勇司、五島直樹
    • Organizer
      第39回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-12-02
    • Invited
    • Data Source
      KAKENHI-PROJECT-26350978
  • [Presentation] X線1分子追跡(DXT)法によるα7ニコチン性アセチルコリン受容体のリアルタイム1分子動態計測2016

    • Author(s)
      馬場知之、大橋澄子、関口博史、池崎圭吾、三尾和弘、佐々木裕次、久保泰
    • Organizer
      第39回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-12-02
    • Data Source
      KAKENHI-PROJECT-26350978
  • [Presentation] X-ray imaging of single protein's motion with ultra-high speed and accuracy2016

    • Author(s)
      Tomoyuki Baba, Keigo Ikezaki, Hiroshi Sekiguchi, Tai Kubo, Yuji C. Sasaki
    • Organizer
      The 31st International Congress on High-speed Imaging and Photonics
    • Place of Presentation
      ホテル阪急エキスポパーク(大阪府吹田市)
    • Year and Date
      2016-11-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26350978
  • [Presentation] 2種類の抗サバイビンバインダー(Three-FingerとVHH抗体)のサバイビン阻害活性2016

    • Author(s)
      安斎宏紀、鈴木武尊、四本勇也、木村慎之介、鈴木美穂、久保泰、根本直人
    • Organizer
      第39回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-11-30
    • Data Source
      KAKENHI-PROJECT-26350978
  • [Presentation] イオンチャネルの遷移状態識別プローブ創製に向けて2016

    • Author(s)
      久保泰
    • Organizer
      大阪大学蛋白質研究所セミナー
    • Place of Presentation
      大阪大学蛋白質研究所(大阪府豊中市)
    • Year and Date
      2016-05-12
    • Invited
    • Data Source
      KAKENHI-PROJECT-26350978
  • [Presentation] Realtime single molecular motion analysis of nicotinic acetylcholine receptor alpha 7 by diffracted X-ray tracking method2016

    • Author(s)
      Kubo, T., Baba, T., Ikezaki, K., Sekiguchi, H., Nishino, Y., Miyazawa, A., Sasaki, Y.C.
    • Organizer
      60th Annual Meeting of Biophysical Society
    • Place of Presentation
      ロサンゼルス(米国)
    • Year and Date
      2016-02-29
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26350978
  • [Presentation] X線回折点追跡法と試験管内分子進化技術の融合によるチャネル分子の遷移過程識別プローブの創製2016

    • Author(s)
      久保泰
    • Organizer
      第68回埼玉大学脳科学セミナー
    • Place of Presentation
      埼玉大学(埼玉県さいたま市)
    • Year and Date
      2016-07-26
    • Invited
    • Data Source
      KAKENHI-PROJECT-26350978
  • [Presentation] 3D Motion Maps of TRPV1 cation channel depicted by Diffracted X-Ray Tracking Method2016

    • Author(s)
      Kazuhiro Mio, Keigo, Ikezaki, Hiroshi Sekiguchi, Yufuku Matsushita, Tai Kubo, Yuji C. Sasaki
    • Organizer
      第54回生物物理学会
    • Place of Presentation
      つくば国際会議場(茨城県つくば市)
    • Year and Date
      2016-11-27
    • Data Source
      KAKENHI-PROJECT-26350978
  • [Presentation] In vitro evolution from pluripotent peptide libraries with natural neurotoxin scaffolds to target receptors, proteases and trophic factors2015

    • Author(s)
      Kubo, T., Naimuddin, M., Ono, S.
    • Organizer
      29th Annual Symposium of the Protein Society
    • Place of Presentation
      バルセロナ(スペイン)
    • Year and Date
      2015-07-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26350978
  • [Presentation] 加速進化型ペプチドのスキャフォールドを利用した分子認識2015

    • Author(s)
      久保泰
    • Organizer
      人工認識分子研究会
    • Place of Presentation
      大阪(大阪)
    • Year and Date
      2015-06-23
    • Invited
    • Data Source
      KAKENHI-PROJECT-26350978
  • [Presentation] Pluripotent random peptide library inspired by natural neurotoxins in the accelerated gene evolution2015

    • Author(s)
      Kubo, T., Naimuddin, M., Ono, S.
    • Organizer
      10th European Biophysics Congress
    • Place of Presentation
      ドレスデン (ドイツ)
    • Year and Date
      2015-07-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26350978
  • [Presentation] Utilization of neurotoxin-inspired peptide libraries in in-vitro evolution, and its proved pluripotency to target GPCRs, proteases and trophic factors2015

    • Author(s)
      Kubo, T., Naimuddin, M., Ono, S., Hirokawa, T.
    • Organizer
      18th World Congress of the International Society on Toxinology
    • Place of Presentation
      オックスフォード(英国)
    • Year and Date
      2015-09-25
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26350978
  • [Presentation] 加速進化型ペプチドの分子骨格を利用した多能性ペプチドライブラリの利用技術2015

    • Author(s)
      久保泰
    • Organizer
      第20回分子複合医薬研究会
    • Place of Presentation
      池田
    • Year and Date
      2015-02-26
    • Invited
    • Data Source
      KAKENHI-PROJECT-26350978
  • [Presentation] パプアピグミーマルガスネークの生理活性ペプチドおよびタンパク質に関する研究2015

    • Author(s)
      山内瑶子、木本 光、鳥羽通久、久保 泰、稲垣 英利
    • Organizer
      第62回トキシンシンポジウム
    • Place of Presentation
      志摩(三重)
    • Year and Date
      2015-07-10
    • Data Source
      KAKENHI-PROJECT-26350978
  • [Presentation] 加速進化型ペプチドのscaffoldに基づく多能性ペプチドライブラリの構築と標的特異的分子の創製2014

    • Author(s)
      久保泰
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2014-11-26
    • Data Source
      KAKENHI-PROJECT-26350978
  • [Presentation] Utilization of three-finger peptide library and evolution in vitro toward protease inhibitors.2014

    • Author(s)
      Cai, W., Kubo, T.
    • Organizer
      10th IST Asia Pacific Congress on Animal, Plant and Microbial Toxins
    • Place of Presentation
      Changsha, China
    • Year and Date
      2014-06-16
    • Data Source
      KAKENHI-PROJECT-26350978
  • [Presentation] 高速1分子内ダイナミクス計測で捉えるアセチルコリン受容体・機能運動

    • Author(s)
      関口博史、徳江真紀、西野有里、一柳光平、久保泰、宮澤淳夫、八木直人、佐々木裕次
    • Organizer
      第14回日本蛋白質科学会
    • Place of Presentation
      横浜
    • Year and Date
      2014-06-25 – 2014-06-27
    • Data Source
      KAKENHI-PROJECT-26350978
  • 1.  KIMURA Tadashi (60344214)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 2.  NUMA SHOSAKU (50025516)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  NODA MASAHARU (60172798)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  Kameyama Kimihiko (50224697)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  Sasaki Yuji (30344401)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  MORIGAKI Kenichi (10358179)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  SHIBAHARA SHIGEKI (00154253)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  MISHINA MASAYOSHI (80144351)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  FUJITA Yoshihiko (80192730)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  FUKUDA Kazuhiko (90199224)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  TAKESHIMA Hiroshi (70212024)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  TANABE Tsutomu (70183069)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  IMOTO Keiji (00176512)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  HEIKE Yuji (90260322)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  関口 博史 (00401563)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  柴山 修哉 (20196439)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  宮澤 淳夫 (60247252)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  一柳 光平 (70435618)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  五島 直樹 (70215482)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  根本 直人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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