Doi Mitsunobu 土井光暢

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DOI Mitsunobu 土井光暢

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Researcher Number	10183500
Other IDs
Affiliation (based on the past Project Information) *help	2010: 大阪薬科大学, 大阪薬科大学, 教授 2007 – 2010: 大阪薬科大学, 薬学部, 教授 2008 – 2009: Osaka University of Pharmaceutical Sciences, 教授 1994 – 1997: 大阪薬科大学, 薬学部, 助教授 1993: 大阪薬科大学, 薬学部, 講師
Review Section/Research Field	Principal Investigator Physical pharmacy / 医薬分子機能学 / Chemical pharmacy Except Principal Investigator Drug development chemistry
Keywords	Principal Investigator NUCLEIC ACID / HETEROMOLECULE / INTERACTION / STRUCTURE / PEPTIDE / PNA / グラミシジンS / HETEROMDLECULE / コラーゲン / コアセルベーション … More / ゲル化 / 結晶化 / CD / βアミノ酸 / 構造活性相関 / 鏡像体(エナンチオマー) / キラリティー / ペプチド / 両親媒体 / ラセミ結晶 / エナンチオマー / 両親媒性 / X線構造解析 … More Except Principal Investigator ペプチド / ドラッグデリバリーシステム / 有機化学 / 薬学 / 細胞膜透過性 / ヘリックス構造 / 膜透過性ペプチド / 二次構造解析 / 非天然型アミノ酸 / ヘリックス / 環状アミノ酸 / リード化合物 / 3次元立体構造 / 免疫制御分子 / 配座固定ライブラリー / ジ置換アミノ酸 Less

Development of cell penetrating peptide utilizing the charactaristic of disubstituted amino acid
- Principal Investigator
  
  Kato Takuma
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Drug development chemistry
- Research Institution
  Osaka University of Pharmaceutical Sciences
Development of dosage form using elastin fragments by incorporation of β-amino acidsPrincipal Investigator
- Principal Investigator
  
  DOI Mitsunobu
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Osaka University of Pharmaceutical Sciences
環状ジ置換アミノ酸配座固定ペプチドライブラリーによる免疫制御分子の探索
- Principal Investigator
  
  Tanaka Masakazu
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Drug development chemistry
- Research Institution
  Nagasaki University
  Kyushu University
Interaction between heteromolecules-Structural study and application of PNA-Principal Investigator
- Principal Investigator
  
  DOI Mitsunobu
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  医薬分子機能学
- Research Institution
  Osaka University of Pharmaceutical Sciences (OUPS)
グラミシジンSの会合状態と細胞膜への作用機構Principal Investigator
- Principal Investigator
  
  土井光暢
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Physical pharmacy
- Research Institution
  Osaka University of Pharmaceutical Sciences
グラミシジンSの会合状態と細胞膜への作用機構-構造解析のためのアプローチ-Principal Investigator
- Principal Investigator
  
  土井光暢
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Physical pharmacy
- Research Institution
  Osaka University of Pharmaceutical Sciences

All 2019 2018 2017 Other

All Journal Article Presentation

[Journal Article] Crystal structure of N-{N-[N-(tert-butoxycarbonyl)-L-α-aspartyl]-L-α-aspartyl}-L-α-aspartic acid 14,24,34-trimethyl ester 31-2-oxo-2-phenylethyl ester {Boc-[Asp(OMe)]3-OPac}2019
- Author(s)
  Kato Takuma、Kishimoto Saki、Asano Akiko、Doi Mitsunobu
- Journal Title
  
  Acta Crystallographica Section E Crystallographic Communications
  
  Volume: 75 Issue: 5 Pages: 585-588
- DOI
  10.1107/s2056989019004596
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H07269
[Journal Article] Left-handed helix of three-membered ring amino acid homopeptide interrupted by an N-H...ethereal O type hydrogen bond2018
- Author(s)
  Y. Koba, A. Ueda, M. Oba, M. Doi, T. Kato, Y. Demizu, M. Tanaka*
- Journal Title
  
  Org. Lett.
  
  Volume: 20 Issue: 24 Pages: 7830-7834
- DOI
  10.1021/acs.orglett.8b03331
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08385, KAKENHI-PROJECT-18K14870, KAKENHI-PROJECT-17H03998, KAKENHI-PROJECT-17H07269, KAKENHI-PROJECT-16K18847
[Journal Article] Crystal structure of 3-(4,4-difluoro-5,7-dimethyl-4-bora-3a,4a-diaza-s-indacen-3-yl)propanoic acid2017
- Author(s)
  Kato Takuma、Doi Mitsunobu
- Journal Title
  
  Acta Crystallographica Section E Crystallographic Communications
  
  Volume: 73 Issue: 12 Pages: 1974-1976
- DOI
  10.1107/s2056989017016942
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H07269
[Journal Article] (2010) Crystal Structure of t-Butyloxy- carbonyl-L-prolyl-L-hydroxyprolyl-glicine methyl ester (Boc-Pro-Hyp-Gly-OMe). Anal. Sci.
- Author(s)
  Asano A., Imori K., Sakaguchi N., Doi M.
- Journal Title
  
  X-Ray Structure Analysis Online 26
  
  Pages: 53-54
- Data Source
  KAKENHI-PROJECT-20590023
[Presentation] ヘリカルペプチドフォルダマーをキラル源とする不斉触媒反応の開発2019
- Author(s)
  梅野智大, 上田篤志, 加藤巧馬, 土井光暢, 田中正一
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-17H07269
[Presentation] Design and Synthesis of Cyclic Disubstituted Amino Acids for Development of Cell Penetrating Peptide2018
- Author(s)
  Takuma Kato, Akiko Asano, Makoto Oba, Masakazu Tanaka, Mitsunobu Doi
- Organizer
  10th International Peptide Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H07269
[Presentation] 膜透過性ペプチドへの応用のための環状ジ置換アミノ酸の合成2018
- Author(s)
  加藤巧馬、大庭　誠、田中正一、土井光暢
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17H07269
[Presentation] Helical peptide-catalyzed asymmetric Michael addition reactions of malonates to cyclic enones2018
- Author(s)
  Tomohiro Umeno, Atsushi Ueda, Takuma Kato, Mitsunobu Doi, Masakazu Tanaka
- Organizer
  10th International Peptide Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H07269
[Presentation] Synthesis of a Chiral Three-Membered Ring α,α-Disubstituted α-Amino Acid Having Two Methyl Groups and Conformational Analysis of its Peptides2018
- Author(s)
  Hikaru Ikeda, Atsushi Ueda, Makoto Oba, Takuma Kato, Mitsunobu Doi, Masakazu Tanaka
- Organizer
  10th International Peptide Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H07269

1. Tanaka Masakazu (00227175)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
2. ASANO Akiko (40291801)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. YAMAMOTO Daisuke (50240106)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. TOMOO Koji (70257898)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. IN Yasuko (50257896)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. ISHIDA Toshimasa (00111021)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. Kato Takuma (20805296)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
8. Oba Makoto (20396716)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
9. 伊東祐二 (60223195)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 樽井麻里子 (60257897)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 出水庸介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Doi Mitsunobu 土井 光暢

DOI Mitsunobu 土井 光暢

Research Projects

Research Products

Co-Researchers

Development of cell penetrating peptide utilizing the charactaristic of disubstituted amino acid

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of dosage form using elastin fragments by incorporation of β-amino acidsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

環状ジ置換アミノ酸配座固定ペプチドライブラリーによる免疫制御分子の探索

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Interaction between heteromolecules-Structural study and application of PNA-Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

グラミシジンSの会合状態と細胞膜への作用機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

グラミシジンSの会合状態と細胞膜への作用機構-構造解析のためのアプローチ-Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Crystal structure of N-{N-[N-(tert-butoxycarbonyl)-L-α-aspartyl]-L-α-aspartyl}-L-α-aspartic acid 14,24,34-trimethyl ester 31-2-oxo-2-phenylethyl ester {Boc-[Asp(OMe)]3-OPac}2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Left-handed helix of three-membered ring amino acid homopeptide interrupted by an N-H...ethereal O type hydrogen bond2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Crystal structure of 3-(4,4-difluoro-5,7-dimethyl-4-bora-3a,4a-diaza-s-indacen-3-yl)propanoic acid2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] (2010) Crystal Structure of t-Butyloxy- carbonyl-L-prolyl-L-hydroxyprolyl-glicine methyl ester (Boc-Pro-Hyp-Gly-OMe). Anal. Sci.

Author(s)

Journal Title

Data Source

[Presentation] ヘリカルペプチドフォルダマーをキラル源とする不斉触媒反応の開発2019

Author(s)

Organizer

Data Source

[Presentation] Design and Synthesis of Cyclic Disubstituted Amino Acids for Development of Cell Penetrating Peptide2018

Author(s)

Organizer

Data Source

[Presentation] 膜透過性ペプチドへの応用のための環状ジ置換アミノ酸の合成2018

Author(s)

Organizer

Data Source

[Presentation] Helical peptide-catalyzed asymmetric Michael addition reactions of malonates to cyclic enones2018

Author(s)

Organizer

Data Source

[Presentation] Synthesis of a Chiral Three-Membered Ring α,α-Disubstituted α-Amino Acid Having Two Methyl Groups and Conformational Analysis of its Peptides2018

Author(s)

Organizer

Data Source

Doi Mitsunobu 土井光暢

DOI Mitsunobu 土井光暢