Yamaguchi Yasuchika 山口泰史

… Alternative Names

山口泰史ヤマグチヤスチカ

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Researcher Number	10183980
Other IDs
Affiliation (Current)	2025: 長崎国際大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2017 – 2020: 長崎国際大学, 薬学部, 教授 2012 – 2015: 長崎国際大学, 薬学部, 教授
Review Section/Research Field	Principal Investigator Drug development chemistry / Living organism molecular science
Keywords	Principal Investigator ペプチドライブラリー / ホスホヒスチジン / 有機合成化学 / 情報伝達系 / ケミカルバイオロジー / N-リン酸化 / 抗菌活性

Chemical approach towards identifying a putative receptor of N-phosphorylated proteinsPrincipal Investigator
- Principal Investigator
  
  Yamaguchi Yasuchika
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Nagasaki International University
Drug discovery research: Searching for a new antibiotics based on stable phospho-histidine mimicsPrincipal Investigator
- Principal Investigator
  
  Yamaguchi Yasuchika
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Living organism molecular science
- Research Institution
  Nagasaki International University

All 2019 2018 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation Book

[Book] 薬系有機化学2018
- Author(s)
  安藤　章、山口　泰史　他
- Total Pages
  454
- Publisher
  南江堂
- ISBN
  9784524403349
- Data Source
  KAKENHI-PROJECT-17K08382
[Book] 新編　医薬化学2018
- Author(s)
  日比野、石倉、北川、須本、波多江、山口　泰史　他
- Total Pages
  368
- Publisher
  廣川書店
- ISBN
  9784567461566
- Data Source
  KAKENHI-PROJECT-17K08382
[Book] 大学生のための有機反応問題集第2版2018
- Author(s)
  山口　泰史
- Total Pages
  120
- Publisher
  三共出版
- ISBN
  9784782707777
- Data Source
  KAKENHI-PROJECT-17K08382
[Book] 新有機医薬品合成化学2012
- Author(s)
  青柳榮、川﨑知己、小林　進、田口武夫、長坂達夫、東山公男、堀江利治、松本隆司、宮岡宏明、山口泰史
- Total Pages
  355
- Publisher
  廣川書店
- Data Source
  KAKENHI-PROJECT-24510311
[Journal Article] Establishment of a quantitative and qualitative analysis and isolation method for tetracyclic iridoids from Morinda lucida Bentham leaves.2019
- Author(s)
  Ohta T, Tilkanont T, Ayertey F, Nakagawa M, Tung NH, Bolah P, Blagogee H, Appiah AA, Ocloo A, Ohashi M, Tanoue K, Yamaguchi Y, Ohta N, Yamaoka S, Iwanaga S, Uto T, Shoyama S.
- Journal Title
  
  Journal of Pharmaceutical and Biomedical Analysis
  
  Volume: 164 Pages: 475-480
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08382
[Journal Article] Selective and reversible modification of kinase cysteines with chlorofluoroacetamides2019
- Author(s)
  Shindo N, Fuchida H,Sato Mi, Watari K, Shibata T, Kuwata K, Miura C, Okamoto K, Hatsuyama Y, Tokunaga K, Sakamoto S, Morimoto S, Abe Y, Shiroishi M, Caaveiro J. M. M., Ueda T, Tamura T, Matsunaga N, Nakao T, Koyanagi S, Ohdo S, Yamaguchi Y, Hamachi I, Ono M, Ojida A
- Journal Title
  
  Nature Chemical Biology
  
  Volume: 15 Issue: 3 Pages: 250-258
- DOI
  10.1038/s41589-018-0204-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08382, KAKENHI-PLANNED-17H06349, KAKENHI-PROJECT-17K15483
[Journal Article] n-vitro Anti-trypanosomal Activities and Mechanisms of Action of Novel Tetracyclic Iridoids from Morinda lucida Benth2016
- Author(s)
  K Kwofie, N Tung, M Suzuki-Ohashi, M Amoa-Bosompem, R Adegle, M Sakyiamah, F Ayertey, K Owusu, I Tuffour, P Atchoglo, K Frempong, W Anyan, T Uto, O Morinaga, T Yamashita, F Aboagye, A Appiah, R Appiah-Opong, A Nyarko, Y Yamaguchi, D Edoh, K Koram, S Yamaoka, D Boakye, N Ohta, Y Shoyama, I Ayi
- Journal Title
  
  Antimicrobial Agents and Chemotherapy
  
  Volume: 60 Issue: 6 Pages: 3283-3290
- DOI
  10.1128/aac.01916-15
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24510311
[Journal Article] A high-affinity fluorescent Zn2+ sensor improved by the suppression of pyridine-pyridone tautomerism and its application in living cells2015
- Author(s)
  Masayori Hagimori, Takashi Temma, Naoko Mizuyama, Takuhiro Uto, Yasuchika Yamaguchi, Yoshinori Tominaga, Takahiro Mukai, and Hideo Saji
- Journal Title
  
  Sensors and Actuators B: Chemical
  
  Volume: 213 Pages: 45-52
- DOI
  10.1016/j.snb.2015.02.063
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24510311
[Journal Article] Determination of the absolute configuration of the novel anti-trypanosomal iridoid molucidin isolated from Morinda lucida by X-ray analysis,2015
- Author(s)
  Satoru Karasawa, Kenji Yoza, Nguyen Huu Tung, Takuhiro Uto, Shoji Yamaoka, Nobuo Ohta, Yukihiro Shoyama, 外27名、
- Journal Title
  
  Tetrahedron Lett.
  
  Volume: 56 Issue: 52 Pages: 7158-7160
- DOI
  10.1016/j.tetlet.2015.11.031
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26620070, KAKENHI-PROJECT-24510311, KAKENHI-PROJECT-25288038
[Journal Article] New anti-trypanosomal active tetracyclic irridoid isolated from Morinda lucida Benth2015
- Author(s)
  M Suzuki; NH Tung; KD Kwofie; R Adegle; M Amoa-Bosompem; M Sakyiamah; F Ayertey; KB-A Owusu; I Tuffour; P Atchoglo; KK Frempong; WK Anyan; T Uto; O Morinaga; T Yamashita; F Aboagye; AA Appiah; R Appiah-Opong; AK Nyarko; . Yamaoka; Y Yamaguchi; D Edoh; K Koram; N Ohta; DA Boakye; I Ayi; Y Shoyama
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 25 Issue: 15 Pages: 0-0
- DOI
  10.1016/j.bmcl.2015.05.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24510311
[Journal Article] 亜鉛イオン応答性ピリジン－ピリドン型蛍光プローブを用いた細胞内亜鉛分布解析への挑戦（その1）/ Challenges to detect an intracellular localization of zinc ion by Zn2+ responsive fluorescent probe, a pyridine-pyridone derivative2015
- Author(s)
  藤田英明、楢崎彩香、大久保麻佳、藤井佑樹、藤原俊幸、萩森政頼、山口泰史 / Hideaki FUJITA, Ayaka NARAZAKI, Asaka OHKUBO, Yuki FUJII, Toshiyuki FUJIWARA, Masayori HAGIMORI, Yasuchika YAMAGUCHI
- Journal Title
  
  長崎国際大学論叢 / Nagasaki International University review
  
  Volume: 15 Pages: 186-192
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24510311
[Journal Article] 体験から考える創薬化学2： Es war einmal./Once upon a time.2014
- Author(s)
  山口　泰史
- Journal Title
  
  MEDCHEM NEWS
  
  Volume: 24(4) Pages: 8-11
- NAID
  130007674620
- Data Source
  KAKENHI-PROJECT-24510311
[Journal Article] Anti-trypanosomal Activity of Diarylheptanoids Isolated from the Bark of Alnus japonica Steud.2014
- Author(s)
  Nguyen Huu Tung, Mitsuko Suzuki, Takuhiro Uto, Osamu Morinaga, Kofi D. Kwofie, Naa Ammah, Kwadwo A. Koram, Frederic Aboagye, Dominic Edoh, Taizo Yamashita, Yasuchika Yamaguchi, Takao Setsu, Shoji Yamaoka, Nobuo Ohta and Yukihiro Shoyama
- Journal Title
  
  The American Journal of Chinese Medicine
  
  Volume: 42 Pages: 0-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24510311
[Journal Article] Anti-Trypanosomal Activity of Diarylheptanoids Isolated from the Bark of Alnus japonica2014
- Author(s)
  Nguyen Huu Tung, Mitsuko Suzuki, Takuhiro Uto, Osamu Morinaga, Kofi D. Kwofie, Naa Ammah, Kwadwo A. Koram, Frederic Aboagye, Dominic Edoh, Taizo Yamashita, Yasuchika Yamaguchi, Takao Setsu, Shoji Yamaoka, Nobuo Ohta, Yukihiro Shoyama
- Journal Title
  
  The American Journal of Chinese Medicine
  
  Volume: 42 Pages: 1245-1260
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24510311
[Journal Article] 体験から考える創薬化学：Es war einmal. / Once upon a time.2013
- Author(s)
  山口泰史
- Journal Title
  
  MEDCHEM NEWS
  
  Volume: 23 Pages: 6-10
- NAID
  130007869038
- Data Source
  KAKENHI-PROJECT-24510311
[Journal Article] Fluorescence ON/OFF switching Zn2+ sensor based on pyridine-pyridone scaffold2013
- Author(s)
  Masayori Hagimori, Takuhiro Uto, Naoko Mizuyama, Takashi Temma, Yasuchika Yamaguchi, Yoshinori Tominaga, Hideo Saji
- Journal Title
  
  Sensors and Actuators B: Chemical
  
  Volume: 181 Pages: 823-828
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24510311
[Journal Article] 体験から考える創薬化学：Es war einmal./Once upon a time.2013
- Author(s)
  山口泰史
- Journal Title
  
  MEDCHEM NEWS
  
  Volume: 23 Pages: 6-10
- NAID
  130007869038
- Data Source
  KAKENHI-PROJECT-24510311
[Presentation] Morinda lucida含有テトラサイクリックイリドイドの定量分析法の開発2018
- Author(s)
  太田智絵，Tanatorn Tilkanont，Nguyen Huu Tung, Frederick Ayertey，田上兼輔，Alfred A. Appiah，Augustine Ocloo，大橋光子，宇都拓洋，山口泰史，岩永史郎，太田伸生，正山征洋
- Organizer
  日本薬学会第138年会（金沢）
- Data Source
  KAKENHI-PROJECT-17K08382
[Presentation] いかにして、活性ある化合物（functionally active compounds）を見つけだすか？：先人に学ぶ2017
- Author(s)
  山口　泰史
- Organizer
  日産化学株式会社　創薬セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-17K08382
[Presentation] 分子内アシル化反応によるペプチド合成法の開発2016
- Author(s)
  田中啓太郎、田上兼輔、今村和也、小田稜子、橋本峻志、松尾綾香、山口泰史
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜市
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-24510311
[Presentation] 失敗と困難から学ぶ創薬研究：Once upon a time in Switzerland and America.2015
- Author(s)
  山口泰史
- Organizer
  日産化学　創薬セミナー
- Place of Presentation
  日産化学　物質科学研究所、千葉県船橋市
- Year and Date
  2015-06-18
- Invited
- Data Source
  KAKENHI-PROJECT-24510311
[Presentation] High affinity fluorescent probe for Zn2+ based on bipyridine scaffold2014
- Author(s)
  Masayori Hagimoria, Naoko Mizuyamab, Yasuchika Yamaguchic, Hideo Sajid, Takahiro Mukai
- Organizer
  World Molecular Imaging Congress, 2014
- Place of Presentation
  South Korea, Seoul
- Data Source
  KAKENHI-PROJECT-24510311
[Presentation] プロジェクトから考える創薬研究：Es war einmal in Basel, La Jolla und Connecticut2014
- Author(s)
  山口　泰史
- Organizer
  第72回講演会有機化学研究会（白鷺セミナー）
- Place of Presentation
  大阪府大阪市、大阪府立大学
- Year and Date
  2014-12-05
- Invited
- Data Source
  KAKENHI-PROJECT-24510311
[Presentation] 分子内アシル転位を利用したペプチド合成2014
- Author(s)
  田中　啓太郎、田中　誠一、山口　泰史
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本県熊本市
- Data Source
  KAKENHI-PROJECT-24510311
[Presentation] 降圧薬プロジェクトから考える創薬研究2013
- Author(s)
  山口泰史
- Organizer
  SYMPOSIUM2013 公開記念シンポジウム　創薬研究の潮流
- Place of Presentation
  福岡
- Invited
- Data Source
  KAKENHI-PROJECT-24510311
[Presentation] Activation of acyl group with sodium iodide2013
- Author(s)
  Keitaro Tanaka, Masayori Hagimori, Yasuchika Yamaguchi
- Organizer
  The 23rd French-Japanese Symposium on Medicinal and Fine Chemistry (Nagasaki)
- Place of Presentation
  Nagasaki
- Data Source
  KAKENHI-PROJECT-24510311
[Presentation] NaIを用いたアシル化剤活性化の検討2013
- Author(s)
  田中啓太郎、田中誠一、萩森政頼、山口泰史
- Organizer
  第30回日本薬学会九州支部大会
- Place of Presentation
  長崎県佐世保市
- Data Source
  KAKENHI-PROJECT-24510311
[Presentation] 生体内亜鉛イオンのイメージングを目的とした低分子量蛍光プローブの開発2013
- Author(s)
  萩森政頼、水山奈央子、向高弘、山口泰史、富永義則、佐治英郎
- Organizer
  第24回日本微量元素学会学術集会
- Place of Presentation
  大阪府吹田市
- Data Source
  KAKENHI-PROJECT-24510311
[Presentation] NaIによるアシル化剤活性化2013
- Author(s)
  田中啓太郎、萩森政頼、山口泰史
- Organizer
  日本薬学会第133回年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24510311
[Presentation] 亜鉛輸送体ZIP14の細胞内輸送および機能発現制御に関する基礎的解析2013
- Author(s)
  大久保　麻佳、楢崎彩香、萩森政頼、山口泰史、藤井佑樹、藤原俊幸、徳永研三、藤田英明
- Organizer
  第30回日本薬学会九州支部大会
- Place of Presentation
  長崎県佐世保市
- Data Source
  KAKENHI-PROJECT-24510311
[Presentation] 体験から考える創薬化学：Es war einmal in Basel, La Jolla und Connecticut2013
- Author(s)
  山口　泰史
- Organizer
  アステラス製薬・創薬セミナー
- Place of Presentation
  茨城県つくば市
- Invited
- Data Source
  KAKENHI-PROJECT-24510311
[Presentation] Zn2+ Selective Fluorescent Probe Based on the Bipyridine Scaffold for Biological Applications2012
- Author(s)
  Masayori HAGIMORI, Naoko MIZUYAMA, Takahiro MUKAI, Yasuchika YAMAGUCHI, Yoshinori TOMINAGA, and Hideo SAJI
- Organizer
  第22回金属の関与する生体関連反応シンポジウム（SRM2012）
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-24510311
[Presentation] ルイス酸フリーのFriedel-Craftsアシル化反応の開発2012
- Author(s)
  濱崎翔平、萩森政頼、田中啓太郎、山口泰史
- Organizer
  第49回化学関連支部合同九州大会
- Place of Presentation
  小倉
- Data Source
  KAKENHI-PROJECT-24510311
[Presentation] 亜鉛イオンに対して高親和性を有する低分子量蛍光プローブの開発2012
- Author(s)
  萩森政頼、水山奈央子、天滿敬、向高弘、山口泰史、富永義則、佐治英朗
- Organizer
  第10回次世代を担う若手のためのフィジカル・ファーマフォーラム
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24510311
[Presentation] NaIによるアシル化剤活性化機構を利用した反応開発
- Author(s)
  田中啓太郎、田中誠一、山口泰史
- Organizer
  日本薬学会第134年会
- Place of Presentation
  兵庫県神戸市
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-24510311
[Presentation] アミノアルコールを含むジペプチドの合成
- Author(s)
  田中啓太郎、田中誠一、梶原宏恵、加茂章弘、東叶奈、山口泰史
- Organizer
  第31会日本薬学会九州支部大会
- Place of Presentation
  福岡県福岡市、第一薬科大学
- Year and Date
  2014-12-06 – 2014-12-07
- Data Source
  KAKENHI-PROJECT-24510311

1. TANAKA Keitaro (60446127)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
2. HAGIMORI Masayori (40446125)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
3. KINO Toru

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 唐沢悟

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yamaguchi Yasuchika 山口 泰史

山口 泰史 ヤマグチ ヤスチカ

Research Projects

Research Products

Co-Researchers

Chemical approach towards identifying a putative receptor of N-phosphorylated proteinsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Drug discovery research: Searching for a new antibiotics based on stable phospho-histidine mimicsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 薬系 有機化学2018

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Book] 新編 医薬化学2018

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Book] 大学生のための有機反応問題集 第2版2018

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Book] 新有機医薬品合成化学2012

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Establishment of a quantitative and qualitative analysis and isolation method for tetracyclic iridoids from Morinda lucida Bentham leaves.2019

Author(s)

Journal Title

Data Source

[Journal Article] Selective and reversible modification of kinase cysteines with chlorofluoroacetamides2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] n-vitro Anti-trypanosomal Activities and Mechanisms of Action of Novel Tetracyclic Iridoids from Morinda lucida Benth2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A high-affinity fluorescent Zn2+ sensor improved by the suppression of pyridine-pyridone tautomerism and its application in living cells2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Determination of the absolute configuration of the novel anti-trypanosomal iridoid molucidin isolated from Morinda lucida by X-ray analysis,2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] New anti-trypanosomal active tetracyclic irridoid isolated from Morinda lucida Benth2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 亜鉛イオン応答性ピリジン－ピリドン型蛍光プローブを用いた細胞内亜鉛分布解析への挑戦 （その1）/ Challenges to detect an intracellular localization of zinc ion by Zn2+ responsive fluorescent probe, a pyridine-pyridone derivative2015

Author(s)

Journal Title

Data Source

[Journal Article] 体験から考える創薬化学2： Es war einmal./Once upon a time.2014

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Anti-trypanosomal Activity of Diarylheptanoids Isolated from the Bark of Alnus japonica Steud.2014

Author(s)

Yamaguchi Yasuchika 山口泰史

山口泰史ヤマグチヤスチカ

[Book] 薬系有機化学2018

[Book] 新編　医薬化学2018

[Book] 大学生のための有機反応問題集第2版2018

[Journal Article] 亜鉛イオン応答性ピリジン－ピリドン型蛍光プローブを用いた細胞内亜鉛分布解析への挑戦（その1）/ Challenges to detect an intracellular localization of zinc ion by Zn2+ responsive fluorescent probe, a pyridine-pyridone derivative2015