ISHIBASHI Fumito 石橋郁人

… Alternative Names

石橋郁人イシバシフミト

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Researcher Number	10192486
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2015 – 2018: 長崎大学, 水産・環境科学総合研究科(水産), 教授 2016: 長崎大学, 水産・環境科学総合研究科 (水産), 教授 2011: 長崎大学, 水産・環境科学総合研究科, 教授 2010 – 2011: 長崎大学, 大学院・水産・環境科学総合研究科, 教授 2007 – 2010: Nagasaki University, 大学院・生産科学研究科, 教授 … More 2008: 長崎大学, 生産科学研究科, 教授 1997 – 2002: 長崎大学, 水産学部, 助教授 1994 – 1995: 長崎大学, 水産学部, 助教授 Less
Review Section/Research Field	Principal Investigator Fisheries chemistry / Fisheries chemistry / Bioproduction chemistry/Bioorganic chemistry / Aquatic life science Except Principal Investigator Drug development chemistry / Bioorganic chemistry / Living organism molecular science
Keywords	Principal Investigator 海洋天然物 / ラメラリン / ピロールアルカロイド / 生理活性 / アルカロイド / 有機化学 / 癌 / トポイソメラーゼ阻害活性 / 脂溶性TPPカチオン / 抗がん活性 … More / トポイソメラーゼ阻害 / 海産アルカロイド / ミトコンドリア標的薬 / トリフェニルホスホニウムカチオン / 抗がん活性化合物 / トポイソメラーゼ / ミトコンドリア / red tide phytoplanktons / algicidal activity / photosystem II inhibitor / enantiometric total synthesis / cyanobacterin / 光合成阻害剤 / 赤潮プランクトン / 殺藻活性 / 光合成阻害 / 全合成 / 光学活性体 / シアノバクテリン / Structure-Activity Relationship / Cytotoxicity / Alkaloid / Marine Natural Product / Lamellarin / 構造活性相関 / 細胞毒性 / 海産天然物 / 分子設計 / トポイソメラーゼI阻害 / 生理活性物質 / 天然物化学 / ディクティオデンドリン / 合成 / テロメラーゼ阻害活性 / シクロペンタベンゾフラン / 殺虫活性 / ロカグラミド / ラメラリンD … More Except Principal Investigator ラメラリン / アファチニブ / 薬剤耐性変異 / アザアメラリン / オシメルチニブ / ゲフィチニブ / L858R/T790M/C797S / L858R/T790M / アザラメラリン / オシメルチニブ耐性 / ゲフィチニブ耐性 / L858R/T790M/C797S変異 / L858R/T790M変異 / EGFR-TKI / 非小細胞肺がん / LITHIATION / INDOLE / ANTITUMOR COMPOUNDS / VEIUTAMINE / MAKALUVAMINES / PYRROLOIMINOQUINONE / MARINE NATURAL PRODUCTS / 海洋アルカロイド / ピロロイミノキノン / リチオ化 / インドール / 抗腫瘍性 / ベイユタミン / マカルバミン / ピロロイキノミノン / 海洋天然物 / トポイソメラーゼ1 / HPLC / サイクリン依存性キナーゼ / 軸不斉 / 分子機構 / サイクリン依存性キナーゼ阻害 / トポイソメラーゼI阻害 / アルツハイマー病 / 神経変成疾患 / がん / キナーゼ阻害剤 / 光学分割 / 軸不斉化合物 / ラメラリンN / 活性発現分子機構 / ドッキングシミュレーション / 構造活性相関 / 選択的阻害剤 / プロテインキナーゼ / トポイソメラーゼI / 抗がん剤 Less

Design, synthesis and biological evaluation of novel lamellarin derivatives targeting cancer cells mitochondriaPrincipal Investigator
- Principal Investigator
  
  ISHIBASHI Fumito
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Aquatic life science
- Research Institution
  Nagasaki University
Development of EGFR-Tyrosine Kinase Inhibitors Effective for Non-Small Cell Lung Cancer Resistant to Gefitinib
- Principal Investigator
  
  IWAO Masatomo
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Nagasaki University
Design and synthesis of novel anticancer compound based on the molecular mode of action of the marine pyrrole alkaloid lamellarinPrincipal Investigator
- Principal Investigator
  
  ISHIBASHI Fumito
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Fisheries chemistry
- Research Institution
  Nagasaki University
Elucidation and Control of the Molecular Mechanism of Action of the Multifunctional Antitumor Agents Lamellarins
- Principal Investigator
  
  IWAO Masatomo
- Project Period (FY)
  2008 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  Nagasaki University
Design and synthesis of telomerase inhibitors based on marine alkaloidesPrincipal Investigator
- Principal Investigator
  
  ISHIBASHI Fumito
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Fisheries chemistry
- Research Institution
  Nagasaki University
Development of a novel photosynthesis inhibitor based on cyanobacterinPrincipal Investigator
- Principal Investigator
  
  ISHIBASHI Fumito
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Fisheries chemistry
- Research Institution
  Nagasaki University
Development of a novel antitumor agent based on a marine alkaloid lamellarinPrincipal Investigator
- Principal Investigator
  
  ISHIBASHI Fumito
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Fisheries chemistry
- Research Institution
  Nagasaki University
STUDIES ON THE SYNTHESIS OF ANTITUMOR PYRROLOIMINOQUINONE MARINE ALKALOIDS
- Principal Investigator
  
  IWAO Masatomo
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  NAGASAKI UNIVERSITY
殺虫性ベンゾフラン、ロカグラミドとその関連化合物の合成研究Principal Investigator
- Principal Investigator
  
  石橋郁人
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  Nagasaki University
ベッコウタマガイの多環性アルカロイド、ラメラリン類の合成研究Principal Investigator
- Principal Investigator
  
  石橋郁人
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  Nagasaki University

All 2019 2018 2017 2016 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation Patent

[Journal Article] Synthesis and Evaluation of Topoisomerase I Inhibitors Possessing the 5,13-Dihydro-6H-benzo[6,7]indolo[3,2-c]quinolin-6-one Scaffold2019
- Author(s)
  Fukuda Tsutomu、Matsuoka Fuyuki、Matsuo Yuri、Yoshioka Naoki、Onodera Gen、Kimura Masanari、Ishibashi Fumito、Iwao Masatomo
- Journal Title
  
  HETEROCYCLES
  
  Volume: 99 Issue: 2 Pages: 1032-1032
- DOI
  10.3987/com-18-s(f)70
- NAID
  120006988387
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K14986, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19K05715, KAKENHI-PUBLICLY-18H04266, KAKENHI-PROJECT-18H01981
[Journal Article] Lamellarin-inspired potent topoisomerase I inhibitors with the unprecedented benzo[g][1]benzopyrano[4,3-b]indol-6(13H)-one scaffold2019
- Author(s)
  Fukuda Tsutomu、Nanjo Yusuke、Fujimoto Masahiro、Yoshida Kenyu、Natsui Yuko、Ishibashi Fumito、Okazaki Fumiyasu、To Hideto、Iwao Masatomo
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 27 Issue: 2 Pages: 265-277
- DOI
  10.1016/j.bmc.2018.11.037
- NAID
  120006987774
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K14986, KAKENHI-PROJECT-16H06276
[Journal Article] Design, synthesis, and evaluation of A-ring-modified lamellarin N analogues as noncovalent inhibitors of the EGFR T790M/L858R mutant2017
- Author(s)
  Tsutomu Fukuda, Teppei Umeki, Keiji Tokushima, Gao Xiang, Yuki Yoshida, Fumito Ishibashi, Yusuke Oku, Naoyuki Nishiya, Yoshimasa Uehara, Masatomo Iwao
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 25 Issue: 24 Pages: 6563-6580
- DOI
  10.1016/j.bmc.2017.10.030
- NAID
  120006987775
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K14986, KAKENHI-PROJECT-15K01802
[Journal Article] Algicidal Activity of Glycerolipids from the Brown Alga Ishige sinicola on Red Tide Microalgae2012
- Author(s)
  Shotaro Hirao, Kenji Tara, Kazuyoshi Kuwano, Junji Tanaka, Fumito Ishibashi
- Journal Title
  
  Biosci. Biotechnol. Biochem
  
  Volume: 76巻 Pages: 372-374
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580248
[Journal Article] Algicidal Activity of Glycerolipids from Brown Alga Ishige sinicola toward Red Tide Microalgae2012
- Author(s)
  Shotaro Hirao, Kenji Tara, Kazuyoshi Kuwano, Junji Tanaka, Fumito Ishibashi
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: 76 Issue: 2 Pages: 372-374
- DOI
  10.1271/bbb.110645
- NAID
  10030400197
- ISSN
  0916-8451, 1347-6947
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580248
[Journal Article] Synthesis and biological activity of lamellarin alkaloids : An overview2011
- Author(s)
  T.Fukuda, F.Ishibashi, M.Iwao
- Journal Title
  
  Heterocycles 83(3)
  
  Pages: 491-529
- NAID
  120006984843
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310135
[Journal Article] Synthesis and biological activity of lamellarin alkaloids : an overview2011
- Author(s)
  T. Fukuda, F. Ishibashi, and M. Iwao
- Journal Title
  
  Heterocycles
  
  Volume: Vol.83, No.3 Pages: 491-529
- NAID
  120006984843
- URL
  http://hdl.handle.net/10069/24666
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310135
[Journal Article] Synthesis, structure. activity relationships, and mechanism of action of anti-HIV-1 lamellarinα20-sulfate analogues2011
- Author(s)
  H. Kamiyama, Y. Kubo, H. Sato, N. Yamamoto, T. Fukuda, F. Ishibashi, and M. Iwao
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: Vol.19, No.24 Pages: 7541-7550
- NAID
  120006985218
- URL
  http://hdl.handle.net/10069/26755
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310135
[Journal Article] Synthesis, structure-activity relationships, and mechanism of action of anti HIV-1 lamellarin α 20-sulfate analogues2011
- Author(s)
  神山陽香, 岩尾正倫, 久保嘉直, 他
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 19 Issue: 24 Pages: 7541-7550
- DOI
  10.1016/j.bmc.2011.10.030
- NAID
  120006985218
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-09J07637, KAKENHI-PROJECT-20310135, KAKENHI-PROJECT-22510235, KAKENHI-PROJECT-22590416
[Journal Article] Synthesis and biological activity of lamellarin alkaloids : an overview2011
- Author(s)
  T.Fukuda, F.Ishibashi, M.Iwao
- Journal Title
  
  Heterocycles
  
  Volume: 83 Pages: 491-529
- NAID
  120006984843
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310135
[Journal Article] Synthesis, structure-activity relationships, and mechanism of action of anti-HIV-1 lamellarin a 20-sulfate analogues2011
- Author(s)
  Haruka Kamiyama, Yoshinao Kubo, Hironori Sato, Naoki Yamamoto, Tsutomu Fukuda, Fumito Ishibashi, Masatomo Iwao
- Journal Title
  
  Bioorg. Med. Chem
  
  Volume: 19巻 Pages: 7541-7550
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580248
[Journal Article] Synthesis and Biological Activity of Lamellarin Alkaloids : An Overview2011
- Author(s)
  Tsutomu Fukuda, Fumito Ishibashi, Masatomo Iwao
- Journal Title
  
  Heterocycles
  
  Volume: 83巻 Pages: 491-529
- NAID
  120006984843
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580248
[Journal Article] A Formal Total Synthesis of the Telomerase Inhibitor Dictyodendrin B2010
- Author(s)
  Shotaro Hirao, Yuki Yoshinaga, Masatomo Iwao, Fumito Ishibashi
- Journal Title
  
  Tetrahedron Lett
  
  Volume: 51巻 Pages: 533-536
- NAID
  120006984589
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580248
[Journal Article] A formal total synthesis of the telomerase inhibitor dictyodendrin B2010
- Author(s)
  S. Hirao, Y. Yoshinaga, M. Iwao, and F. Ishibashi
- Journal Title
  
  Tetrahedron Letters
  
  Volume: Vol.51, No.3 Pages: 533-536
- NAID
  120006984589
- URL
  http://hdl.handle.net/10069/23109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310135
[Journal Article] A formal total synthesis of the telomerase inhibitor dictyodendrin B2010
- Author(s)
  S.Hirao, Y.Yoshinaga, M.Iwao, F.Ishibashi
- Journal Title
  
  Tetrahedron Letters 51
  
  Pages: 533-536
- NAID
  120006984589
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310135
[Journal Article] A formal total synthesis of the telomerase inhibitor dictyodendrin B2010
- Author(s)
  S.Hirao, Y.Yoshinaga, M.Iwao, F.Ishibashi
- Journal Title
  
  Tetrahedron Letters 51(3)
  
  Pages: 533-536
- NAID
  120006984589
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310135
[Journal Article] A Formal Total Synthesis of the Telomerase Inhibitor Dictyodendrin B2010
- Author(s)
  Shotaro Hirao, Yuki Yoshinaga, Masatomo Iwao, Fumito Ishibashi
- Journal Title
  
  Tetrahedron Letters 51
  
  Pages: 533-536
- NAID
  120006984589
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580248
[Journal Article] Synthetic approach to telomerase inhibitor dictyodendrin B : synthesis of the pyrrolo[ 2, 3-c] carbazole core2009
- Author(s)
  S. Hirao, Y. Sugiyama, M. Iwao, and F. Ishibashi
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: Vol.73, No.8 Pages: 1764-1772
- NAID
  10027544373
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310135
[Journal Article] Synthetic Approach to Telomerase Inhibitor Dictyodendrin B : Synthesis of the Pyrrolo[ 2, 3-c] carbazole Core2009
- Author(s)
  Shotaro Hirao, Yumiko Sugiyama, Masatomo Iwao, Fumito Ishibashi
- Journal Title
  
  Biosci. Biotechnol. Biochem
  
  Volume: 73巻 Pages: 1764-1772
- NAID
  10027544373
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580248
[Journal Article] Synthetic Approach to Telomerase Inhibitor Dictyodendrin B : Synthesis of the Pyrrolo[2,3-c]carbazole Core2009
- Author(s)
  Shotaro Hirao, Yumiko Sugiyama, Masatomo Iwao, Fumito Ishibashi
- Journal Title
  
  Bioscience, Biotechnology and Biochemistry 73
  
  Pages: 1764-1772
- NAID
  10027544373
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580248
[Journal Article] Design and Synthesis of Lamellarin D Analogues Targeting Topoisomerase I2009
- Author(s)
  Takeshi Ohta, Tsutomu Fukuda, Fumito Ishibashi, Masatomo Iwao
- Journal Title
  
  J. Org. Chem
  
  Volume: 74巻 Pages: 8143-8153
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580248
[Journal Article] Design and synthesis of lamellarin D analogues targeting topoisomerase I2009
- Author(s)
  T. Ohta, T. Fukuda, F. Ishibashi, and M. Iwao
- Journal Title
  
  The Journal of Organic Chemistry
  
  Volume: Vol.74, No.21 Pages: 8143-8153
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310135
[Journal Article] Design and Synthesis of Lamellarin D Analogues Targeting Topoisomerase I2009
- Author(s)
  Takeshi Ohta, Tsutomu Fukuda, Fumito Ishibashi, Masatomo Iwao
- Journal Title
  
  Journal of Organic Chemistry 74
  
  Pages: 8143-8153
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580248
[Journal Article] Design and synthesis of lamellarin D analogues targeting topoisomerase I2009
- Author(s)
  T.Ohta, T.Fukuda, F.Ishibashi, M.Iwao
- Journal Title
  
  Journal of Organic Chemistry 74(21)
  
  Pages: 8143-8153
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310135
[Journal Article] Synthetic approach to telomerase inhibitor dictyodendrin B : synthesis of the pyrrolo[2,3-c]carbazole core2009
- Author(s)
  S.Hirao, Y.Sugiyama, M.Iwao, F.Ishibashi
- Journal Title
  
  Bioscience Biotechnology, and Biochemistry 73
  
  Pages: 1764-1772
- NAID
  10027544373
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310135
[Journal Article] Synthetic approach toward the telomerase inhibitor dictyodendrin B : Synthesis of the pvrrolo[2, 3-c]-carbazole core2009
- Author(s)
  S. Hirao, Y. Sugiyama, M. Iwao, F. Ishibashi
- Journal Title
  
  Bioscience Biotechnology and Biochemistry 73(印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580238
[Journal Article] Design and synthesis of lamellarin D analogues targeting topoisomerase I2009
- Author(s)
  T.Ohta, T.Fukuda, F.Ishibashi, M.Iwao
- Journal Title
  
  The Journal of Organic Chemistry 74
  
  Pages: 8143-8153
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310135
[Journal Article] Synthetic approach toward the telomerase inhibitor dictyodendrin B : Synthesis of the pyrrolo[2,3-c]-carbazole core2009
- Author(s)
  S. Hirao, Y. Sugiyama, M. Iwao, and F. Ishibashi
- Journal Title
  
  Biosci. Biotechnol. Biochem. accepted
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580238
[Journal Article] Algicidal activity of polyunsaturated fatty acids derived from Ulva fasciata and U.pertusa (Ulvaceae, Chlorophyta) on phytoplankton2008
- Author(s)
  M. A. Alamsjah, S. Hirao, F. Ishibashi, T. Oda, and Y. Fujita
- Journal Title
  
  J. Appl. Phycol. 20
  
  Pages: 713-720
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580238
[Journal Article] Anticancer alkaloid lamellarins inhibit protein kinases2008
- Author(s)
  D. Baunbaek, N. Trinkler, Y. Ferandin, O. Lozach, P. Ploypradith, S. Ruchirawat, F. Ishibashi, M. Iwao, and L. Meijer
- Journal Title
  
  Mar. Drugs 6
  
  Pages: 514-527
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580238
[Journal Article] Anticancer alkaloid lamellarins inhibit protein kinases2008
- Author(s)
  D. Baunbak, N. Trinkler, Y. Ferandin, O. Lozach, P. Ploypradith, S. Rucirawat, F. Ishibashi, M. Iwao, and L. Meijer
- Journal Title
  
  Marine Drugs
  
  Volume: Vol.6, No.4 Pages: 514-527
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310135
[Journal Article] Anticancer Alkaloid Lamellarins Inhibit Protein Kinases2008
- Author(s)
  D. Baunbffik, N. Trinkler, Y. Ferandin, O. Lozach, P. Ploypradith, S. Rucirawat, F. Ishibashi, M. Iwao, L. Meiier
- Journal Title
  
  Marine Drugs 6
  
  Pages: 514-527
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310135
[Journal Article] Algicidal activity of polyunsaturated fatty acids derived from Ulva fasciata and U. pertusa(Ulvaceae, Chlorophyta)on phytoplankton2008
- Author(s)
  M. A. Alamsjah, S. Hirao, F. Ishibashi, T. Oda, Y. Fujita
- Journal Title
  
  Journal of Applied Phycology 20
  
  Pages: 713-720
- NAID
  120006983963
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310135
[Journal Article] Algicidal activity of polyunsaturated fatty acids derived from Ulva fasciata and U.pertusa (Ulvaceae, Chlorophyta) on phytoplankton2008
- Author(s)
  Mochammad Amin Alamsjah, Shotaro Hirao, Fumito Ishibashi, Tatsuya Oda, and Yuji Fujita
- Journal Title
  
  Journal of Applied Phycology (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580238
[Journal Article] Anticancer alkaloid lamellarins inhibit protein kinases2008
- Author(s)
  D.Baunbaeck, N.Trinkler, Y.Ferandin, O.Lozach, P.Ploypradith, S.Ruchirawat, F.Ishibashi, M.Iwao, L.Meijer
- Journal Title
  
  Marine Drugs 6(4)
  
  Pages: 514-527
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20310135
[Journal Article] Anticancer alkaloid lamellarins inhibit protein kinases2008
- Author(s)
  D. Baunbaek, N. Trinkler, Y. Ferandin, O. Lozach, P. Ploypradith, S. Ruchirawat, F. Ishibashi, M. Iwao, L. Meijer
- Journal Title
  
  Marine Drugs 6
  
  Pages: 514-527
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19580238
[Patent] 第四世代EGFRチロシンキナーゼ阻害剤2017
- Inventor(s)
  岩尾正倫、福田勉、石橋郁人　ほか5名
- Industrial Property Rights Holder
  国立大学法人　長崎大学　ほか２法人
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-064866
- Filing Date
  2017-03-29
- Data Source
  KAKENHI-PROJECT-26293028
[Patent] 抗癌活性化合物2012
- Inventor(s)
  岩尾正倫, 石橋郁人, 福田勉, 長谷川寛雄
- Industrial Property Rights Holder
  国立大学法人長崎大学
- Filing Date
  2012-01-17
- Overseas
- Data Source
  KAKENHI-PROJECT-21580248
[Patent] 抗癌活性化合物2012
- Inventor(s)
  岩尾正倫、石橋郁人、福田勉、長谷川寛雄
- Industrial Property Rights Holder
  国立大学法人長崎大学
- Filing Date
  2012-01-17
- Overseas
- Data Source
  KAKENHI-PROJECT-21580248
[Patent] 抗癌活性物質2012
- Inventor(s)
  岩尾正倫、石橋郁人、福田勉、長谷川寛夫
- Industrial Property Rights Holder
  国立大学法人長崎大学
- Industrial Property Number
  2011-007011
- Filing Date
  2012-01-17
- Overseas
- Data Source
  KAKENHI-PROJECT-20310135
[Patent] ベンゾ[g][1]ベンゾピラノ[4,3-b]インドールー6(13H)-オン骨格を持つ抗癌活性化合物2011
- Inventor(s)
  岩尾正倫、石橋郁人、福田勉
- Industrial Property Rights Holder
  国立大学法人長崎大学
- Industrial Property Number
  2011-007011
- Filing Date
  2011-01-17
- Data Source
  KAKENHI-PROJECT-21580248
[Patent] ベンゾ[g][1]ベンゾピラノ[4,3-b]インドール-6(13H)-オン骨格を持つ抗癌活性化合物2011
- Inventor(s)
  岩尾正倫, 石橋郁人, 福田勉
- Industrial Property Rights Holder
  国立大学法人長崎大学
- Industrial Property Number
  2011-007011
- Filing Date
  2011-01-17
- Data Source
  KAKENHI-PROJECT-20310135
[Patent] ベンゾ[g]ベンゾピラノ[4,3-b]インドール-6-(13H)-オン骨格を持つ抗癌活性化合物2011
- Inventor(s)
  岩尾正倫、石橋郁人、福田勉
- Industrial Property Rights Holder
  国立大学法人長崎大学
- Industrial Property Number
  2011-007011
- Filing Date
  2011-01-17
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] デニグリンCの合成研究2018
- Author(s)
  宮本紘季，石橋郁人
- Organizer
  日本農芸化学会西日本支部大会
- Data Source
  KAKENHI-PROJECT-16K14986
[Presentation] 脂溶性カチオン部位結合型ラメラリンの合成2018
- Author(s)
  石橋郁人，安田圭佑，鈴木辰弥
- Organizer
  日本農芸化学会西日本支部大会
- Data Source
  KAKENHI-PROJECT-16K14986
[Presentation] Isolation of algicidal compounds from the red alga Tricleocarpa cylindrica against the red-tide phytoplankton Chattonella antiqua2017
- Author(s)
  Shijiao Zha, Kazuyoshi Kuwano, and Fumito Ishibashi
- Organizer
  The International Symposium Fisheries Science for Future Generations
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K14986
[Presentation] アザラメラリン N 誘導体の効率的合成2016
- Author(s)
  中原茜, 吉田昇太, 安在瑞穂, 福田勉, 石橋郁人, 岩尾正倫
- Organizer
  第53回化学関連支部合同九州大会
- Place of Presentation
  北九州国際会議場 (福岡県北九州市)
- Data Source
  KAKENHI-PROJECT-26293028
[Presentation] Laurent Meijer,光学活性16-メチルラメラリンNの絶対配置の決定とプロテインキナーゼ阻害活性評価2012
- Author(s)
  吉田賢佑, 糸山諒介, 福田勉, 石橋郁人, 岩尾正倫
- Organizer
  日本化学会第92春季年会
- Place of Presentation
  慶応義塾大学(神奈川)
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] 光学活性16-メチルラメラリンNの絶対配置の決定とプロテインキナーゼ阻害活性評価2012
- Author(s)
  吉田賢佑、糸山諒介、福田勉、石橋郁人、岩尾正倫、Laurent Meijer
- Organizer
  日本化学会第92春季年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21580248
[Presentation] 光学活性16-メチルラメラリンNの絶対配置の決定とプロテインキナーゼ阻害活性評価2012
- Author(s)
  吉田賢佑, 糸山諒介, 福田勉, 石橋郁人, 岩尾正倫, Laurent Meijer
- Organizer
  日本化学会第92春季年会
- Place of Presentation
  慶応義塾大学(神奈川県)
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] Total Synthesis of the Marine Pyrrolocarbazole Alkaloid Dictyodendrin B2011
- Author(s)
  S.Hirao, Y.Yoshinaga, M.Iwao, F.Ishibashi
- Organizer
  23^<rd> International Congress of Heterocyclic Chemistry
- Place of Presentation
  英国、グラスゴー
- Year and Date
  2011-08-02
- Data Source
  KAKENHI-PROJECT-21580248
[Presentation] Total Synthesis of the Marine Pyrrolocarbazole Alkaloid Dictyodendrin B2011
- Author(s)
  S. Hirao, Y. Yoshinaga, M. Iwao, F. Ishibashi
- Organizer
  23rd International Congress of Heterocyclic Chemistry
- Place of Presentation
  Glasgow
- Data Source
  KAKENHI-PROJECT-21580248
[Presentation] 海洋産多環性ピロールアルカロイド類の合成と生理活性2011
- Author(s)
  石橋郁人
- Organizer
  日本農芸化学会支部総会・奨励賞受賞講演・特別講演会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-21580248
[Presentation] ラメラリンN誘導体の軸性キラリティーとプロテインキナーゼ阻害活性2011
- Author(s)
  糸山諒介, 吉田賢佑, 福田勉, 石橋郁人, 岩尾正倫, Laurent Meijer
- Organizer
  第41回複素環化学討論会
- Place of Presentation
  熊本市民会館(熊本)
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] ラメラリンN誘導体の軸性キラリティーとプロテインキナーゼ阻害活性2011
- Author(s)
  糸山諒介, 吉田賢佑, 福田勉, 石橋郁人, 岩尾正倫, Laurent Meijer
- Organizer
  第41回複素環化学討論会
- Place of Presentation
  熊本市民会館(熊本県)
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] Design, Synthesis, and Evaluation of Benzo[ g][ 1] benzopyrano[ 4, 3-b] indol-6(13H)-one(BBPI) Ring System as a New Design, Scaffold of Antitumor Agents2011
- Author(s)
  Yusuke Nanjo, Masahiro Fujimoto, Tsutomu Fukuda, Fumito Ishibashi, and Masatomo Iwao
- Organizer
  8th AFMC International Medicinal Chemistry Symposium Frontier of Medicinal Science
- Place of Presentation
  Japan
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] Design, Synthesis, and Evaluation of Benzo[g][1]benzopyrano[4,3-b]indol-6(13H)-one (BBPI) Ring System as a New Scaffold of Antitumor Agents2011
- Author(s)
  Y.Nanjo, M.Fujimoto, T.Fukuda, F.Ishibashi, M.Iwao
- Organizer
  8th AFMC International Medicinal Chemistry Symposium Frontier of Medicinal Science (AIMECS11)
- Place of Presentation
  京王プラザホテル(東京都)
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] 海洋天然物ラメラリンをモデルとした新規トポイソメラーゼI阻害活性物質の創製2011
- Author(s)
  福永光希、柱野彩、石橋郁人、岩尾正倫
- Organizer
  日本農芸化学会西日本支部・中国四国支部合同大会
- Place of Presentation
  宮崎
- Data Source
  KAKENHI-PROJECT-21580248
[Presentation] 抗がん性海洋天然物ラメラリンD類縁体の合成と構造活性相関2010
- Author(s)
  南條佑介, 太田剛, 福田勉, 石橋郁人, 岩尾正倫
- Organizer
  第29回メディシナルケミストリーシンポジウム 2P-30
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] テロメラーゼ阻害活性物質ディクティオデンドリンBの合成2010
- Author(s)
  平尾翔太郎、吉永祐樹、岩尾正倫、石橋郁人
- Organizer
  日本農芸化学会2010年度大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21580248
[Presentation] 抗がん性海洋天然物ラメラリンD類縁体の合成と構造活性相関2010
- Author(s)
  南條佑介, 太田剛, 福田勉, 石橋郁人, 岩尾正倫
- Organizer
  第29回メディシナルケミストリーシンポジウム
- Place of Presentation
  京都テルサ(京都)
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] 硫酸エステル型ピロールアルカロイドの合成研究2010
- Author(s)
  森瀬崇大、石橋郁人
- Organizer
  日本農芸化学会西日本支部大会
- Place of Presentation
  熊本
- Year and Date
  2010-09-18
- Data Source
  KAKENHI-PROJECT-21580248
[Presentation] 硫酸エステル型ピロールアルカロイドの合成研究2010
- Author(s)
  森瀬崇大、石橋郁人
- Organizer
  日本農芸化学会西日本支部大会(第284回)
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-21580248
[Presentation] 抗がん性海洋天然物ラメラリンD類縁体の合成と構造活性相関2010
- Author(s)
  南條佑介, 太田剛, 福田勉, 石橋郁人, 岩尾正倫
- Organizer
  第29回メディシナルケミストリーシンポジウム
- Place of Presentation
  京都テルサ(京都府)
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] テロメラーゼ阻害活性物質ディクティオデンドリンAの合成研究2010
- Author(s)
  吉永祐樹、石橋郁人
- Organizer
  日本農芸化学会西日本支部大会
- Place of Presentation
  熊本
- Year and Date
  2010-09-18
- Data Source
  KAKENHI-PROJECT-21580248
[Presentation] Design and Synthesis of Novel Lamellarin D Analogues Targeting Topoisomerase I2010
- Author(s)
  Takeshi Ohta, Tsutomu Fukuda, Fumito Ishibashi, Masatomo Iwao
- Organizer
  Nagasaki Symposium on Nano-Dynamics 2010(NSND-2010)
- Place of Presentation
  長崎大学(長崎県長崎市)
- Year and Date
  2010-01-21
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] テロメラーゼ阻害活性物質ディクティオデンドリンBの合成2010
- Author(s)
  平尾翔太郎、岩尾正倫、石橋郁人
- Organizer
  日本農芸化学会2010年度大会
- Place of Presentation
  東京大学駒場キャンパス(東京都)
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-21580248
[Presentation] テロメラーゼ阻害活性物質ディクティオデンドリンAの合成研究2010
- Author(s)
  吉永祐樹、平尾翔太郎、石橋郁人
- Organizer
  日本農芸化学会西日本支部大会(第284回)
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-21580248
[Presentation] 海洋産抗腫瘍性アルカロイド・ラメラリンの合成と分子作用機構2009
- Author(s)
  石橋郁人、福田勉、岩尾正倫
- Organizer
  日本農芸化学会2009年度大会
- Place of Presentation
  福岡
- Year and Date
  2009-03-28
- Data Source
  KAKENHI-PROJECT-19580238
[Presentation] テロメラーゼ阻害活性物質ディクティオデンドリンの合成研究 : 基本骨格化合物の合成2009
- Author(s)
  平尾翔太郎、岩尾正倫、石橋郁人
- Organizer
  第39回複素環化学討論会
- Place of Presentation
  さわやかちば県民プラザ(柏市)
- Year and Date
  2009-10-14
- Data Source
  KAKENHI-PROJECT-21580248
[Presentation] テロメラーゼ阻害活性物質ディクティオデンドリンの合成研究:基本骨格化合物の合成2009
- Author(s)
  平尾翔太郎、岩尾正倫、石橋郁人
- Organizer
  第39回複素環化学討論会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-21580248
[Presentation] 抗HIV活性を持つ海洋天然物ラメラリンα 20-サルフェートの合成と生理活性2008
- Author(s)
  石橋郁人
- Organizer
  Biojapan 2008
- Place of Presentation
  横浜
- Year and Date
  2008-10-15
- Data Source
  KAKENHI-PROJECT-19580238
[Presentation] 海洋天然物ラメラリンDをモデルとする新規トポイソメラーゼI阻害剤の設計と合成2008
- Author(s)
  太田剛, 福田勉, 石橋郁人, 岩尾正倫
- Organizer
  第18回万有福岡シンポジウム
- Place of Presentation
  九州大学(福岡市)
- Year and Date
  2008-05-10
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] 褐藻イロロIshige sinicolaの赤潮プランクトンに対する毒性物質2008
- Author(s)
  船橋亮, 多良賢二, 桑野和可, 石橋郁人
- Organizer
  日本農芸化学会2008年度西日本支部大会
- Place of Presentation
  長崎
- Year and Date
  2008-09-20
- Data Source
  KAKENHI-PROJECT-19580238
[Presentation] ディクティオデンドリンの合成研究2008
- Author(s)
  平尾翔太郎、小林祥平、吉永祐樹、石橋郁人、岩尾正倫
- Organizer
  日本農芸化学会2008年度西日本支部大会
- Place of Presentation
  長崎
- Year and Date
  2008-09-20
- Data Source
  KAKENHI-PROJECT-19580238
[Presentation] 抗HIV活性を持つ海洋天然物ラメラリンα20-サルフェートの合成と生理活性2008
- Author(s)
  石橋郁人
- Organizer
  BioJapan 2008
- Place of Presentation
  横浜
- Year and Date
  2008-10-15
- Data Source
  KAKENHI-PROJECT-19580238
[Presentation] 多環性海洋天然物ラメラリンDを先導物質とする新規トポイソメラーゼI阻害剤の設計と合成2008
- Author(s)
  太田剛, 福田勉, 石橋郁人, 岩尾正倫
- Organizer
  第50回天然有機化合物討論会 P-44
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] 多環性海洋天然物ラメラリンDを先導物質とする新規トポイソメラーゼI阻害剤の設計と合成2008
- Author(s)
  太田剛、福田勉、石橋郁人、岩尾正倫
- Organizer
  第50回天然有機化合物討論会
- Place of Presentation
  福岡
- Year and Date
  2008-10-01
- Data Source
  KAKENHI-PROJECT-19580238
[Presentation] 海洋天然物ラメラリンDをモデルとする新規トポイソメラーゼI阻害剤の設計と合成,2008
- Author(s)
  太田剛, 福田勉, 石橋郁人, 岩尾正倫
- Organizer
  第18回万有福岡シンポジウム
- Place of Presentation
  九州大学(福岡)
- Year and Date
  2008-05-10
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] 多環性海洋天然物ラメラリンDを先導物質とする新規トポイソメラーゼI阻害剤の設計と合成2008
- Author(s)
  太田剛, 福田勉, 石橋郁人, 岩尾正倫
- Organizer
  第50回天然有機化合物討論会
- Place of Presentation
  福岡国際会議場(福岡)
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] 多環性海洋天然物ラメラリンDを先導物質とする新規トポイソメラーゼI阻害剤の設計と合成2008
- Author(s)
  太田剛, 福田勉, 石橋郁人, 岩尾正倫
- Organizer
  第50回天然有機化合物討論会講演要旨集
- Place of Presentation
  福岡国際会議場(福岡市)
- Year and Date
  2008-10-01
- Data Source
  KAKENHI-PROJECT-20310135
[Presentation] ディクティオデンドリンの合成研究2008
- Author(s)
  平尾翔太郎、石橋郁人、岩尾正倫
- Organizer
  日本農芸化学会2008年度大会
- Place of Presentation
  名古屋
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-19580238
[Presentation] 海洋天然物ラメラリンDを基盤とする新規抗腫瘍活性物質の設計および合成2007
- Author(s)
  太田剛, 福田勉, 石橋郁人, 岩尾正倫
- Organizer
  第37回複素環化学討論会
- Place of Presentation
  長野
- Year and Date
  2007-10-18
- Data Source
  KAKENHI-PROJECT-19580238
[Presentation] 高活性トポイソメラーゼI阻害剤BBPIの水溶性誘導体の設計・合成・評価
- Author(s)
  佐々木翔, 夏井裕子, 仲山隆太, 藤秀人, 福田勉, 石橋郁人, 岩尾正倫
- Organizer
  第32回メディシナルケミストリーシンポジウム
- Place of Presentation
  札幌市民ホール (北海道札幌市)
- Year and Date
  2014-11-26 – 2014-11-28
- Data Source
  KAKENHI-PROJECT-26293028

1. IWAO Masatomo (00100892)

# of Collaborated Projects: 3 results

# of Collaborated Products: 32 results
2. OSATOMI Kiyoshi (40253702)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. FUKUDA Tsutomu (80295097)

# of Collaborated Projects: 2 results

# of Collaborated Products: 24 results
4. ODA Tatsuya (60145307)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KUWANO Kazuyoshi (60301363)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. UNNO Hideaki (10452872)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. UEHARA Yoshimasa (50160213)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. NISHIYA Naoyuki (10286867)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 平坂勝也 (70432747)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. YASUDA Keisuke

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. SUZUKI Tatsuya

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 神山陽香

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 吉居陽香

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

ISHIBASHI Fumito 石橋 郁人

石橋 郁人 イシバシ フミト

Research Projects

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Co-Researchers

Design, synthesis and biological evaluation of novel lamellarin derivatives targeting cancer cells mitochondriaPrincipal Investigator

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Development of EGFR-Tyrosine Kinase Inhibitors Effective for Non-Small Cell Lung Cancer Resistant to Gefitinib

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Design and synthesis of novel anticancer compound based on the molecular mode of action of the marine pyrrole alkaloid lamellarinPrincipal Investigator

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Elucidation and Control of the Molecular Mechanism of Action of the Multifunctional Antitumor Agents Lamellarins

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Design and synthesis of telomerase inhibitors based on marine alkaloidesPrincipal Investigator

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Development of a novel photosynthesis inhibitor based on cyanobacterinPrincipal Investigator

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Development of a novel antitumor agent based on a marine alkaloid lamellarinPrincipal Investigator

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STUDIES ON THE SYNTHESIS OF ANTITUMOR PYRROLOIMINOQUINONE MARINE ALKALOIDS

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殺虫性ベンゾフラン、ロカグラミドとその関連化合物の合成研究Principal Investigator

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ベッコウタマガイの多環性アルカロイド、ラメラリン類の合成研究Principal Investigator

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[Journal Article] Synthesis and Evaluation of Topoisomerase I Inhibitors Possessing the 5,13-Dihydro-6H-benzo[6,7]indolo[3,2-c]quinolin-6-one Scaffold2019

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[Journal Article] Lamellarin-inspired potent topoisomerase I inhibitors with the unprecedented benzo[g][1]benzopyrano[4,3-b]indol-6(13H)-one scaffold2019

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NAID

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[Journal Article] Design, synthesis, and evaluation of A-ring-modified lamellarin N analogues as noncovalent inhibitors of the EGFR T790M/L858R mutant2017

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ISHIBASHI Fumito 石橋郁人

石橋郁人イシバシフミト