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KOTANI Masaharu  小谷 政晴

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KOTANI Masahary  小谷 政晴

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Researcher Number 10195737
Affiliation (based on the past Project Information) *help 2005: Ohu University, Pharmaceutical Sciences, Associate Professor, 薬学部, 助教授
2002 – 2004: 財団法人東京都医学研究機構, 東京都臨床医学総合研究所, 研究員
2003: 財)東京都医学研究機構, 東京都臨床医学総合研究所, 研究員
1995: 財団法人東京都臨床医学総合研究所, 腫瘍免疫研究部門, 研究員
1995: The Tokyo Metropolitan Institute of Medical Science, Department of Tumor Immunol, 臨床遺伝学研究部門, 研究員
1994: 財団法人 東京都臨床医学総合研究所, 腫瘍免疫研究部門, 研究員
1989 – 1990: Tokyo Metropol.Inst.Med.Sci., Dept.Imm., Research member, 免疫研究部門, 研究員
Review Section/Research Field
Principal Investigator
Neurochemistry/Neuropharmacology / Neurochemistry/Neuropharmacology
Except Principal Investigator
Immunology / Pediatrics
Keywords
Principal Investigator
RANDAM-2 / FACS analysis / cell membrane antigens / neural stem cells / マウス / 神経細胞分化 / Mouse neurospheres / 中枢神経系 / 神経幹細胞 / FAGS analysis … More / mouse neurospheres / Gene cloning / P19 EC cells / Mouse / Monoclonal antibody / Cell surface antigen / Neuronal cell differentiation / 遺伝子クローニング / P19EC細胞 / モノクローナル抗体 / 細胞表面抗原 … More
Except Principal Investigator
遺伝子導入 / ウサギ / CD4 / HIV / エイズ / Immunomodulation / Adhesion molecule / Cell adhesion / Endothelial cell / Homing / Lymphocyte recirculation / Lymphocyte / ホーミング / 接着因子 / 免疫調節 / 接着分子 / 細胞接着 / 内皮細胞 / ホ-ミング / 再循環現象 / リンパ球 / confocal laser scanning microscopy / Three-dimensional images / Volume visualization / Fabry disease / Metachromatic leukodystrophy / Lipidosis / 脳MRI / 異染性脳白質ジストロフィー / ボリュームビジュアライゼーション / レーザー走査型共焦点顕微鏡 / 副腎白質ジストロフィー / 3次元像再構築 / 3次元画像 / ボリューム・ビジュアライゼーション / Fabry病 / 異染性白質ジストロフィー / リピドーシス / 細胞免疫 Less
  • Research Projects

    (6 results)
  • Research Products

    (18 results)
  • Co-Researchers

    (11 People)
  •  Cell biological study of the RANDAM-2 high positive cells and RANDAM-2 low/negative cells in mouse central nervous system.Principal Investigator

    • Principal Investigator
      KOTANI Masaharu
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Ohu University
      Tokyo Metropolitan Organization for Medical Research
  •  cDNA cloning of cell membrane surface antigens involved in the neuronal differentiation and identification of the antigen positive cells in mouse cerebrumPrincipal Investigator

    • Principal Investigator
      KOTANI Masaharu
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  Three-dimensional imaging of cells and tissues for the clarification of pathogenesis of inherited metabolic diseases.

    • Principal Investigator
      SAKURABA Hitoshi
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      The Tokyo Metropolitan Institute of Medical Science
  •  新しい実験的HIV感染in vitroおよびin vivoモデルの作製

    • Principal Investigator
      宮坂 昌之
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  新しい実験的エイズ感染in vitroおよびin vivoモデルの作製

    • Principal Investigator
      MIYASAKA Masayuki
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  Investigation on receptor systems mediating lymphocyte recirculation

    • Principal Investigator
      MIYASAKA Masayuki
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Immunology
    • Research Institution
      Tokyo Metropolitan Institute of Medical Science

All 2005 2004

All Journal Article

  • [Journal Article] Establishment of immortalized Schwann cells from Sandhoff mice and corrective effect of recombinant human beta-hexosaminidase A on the accumulated GM2 ganglioside.2005

    • Author(s)
      Murata, M., Kotani, M., et al.
    • Journal Title

      Journal of Human Genetics 50

      Pages: 460-467

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16500252
  • [Journal Article] Distal myopathy with rimmed vacuoles : Impaired O-glycan formation in sarcolemmal glycoproteins.2005

    • Author(s)
      Tajima, Y., Uyama, E., Go, S., Sato, C., Tao, N., Kotani, M., et al.
    • Journal Title

      American Journal of Pathology 166

      Pages: 1121-1130

    • Data Source
      KAKENHI-PROJECT-16500252
  • [Journal Article] An asymptomatic heterozygous female with Fabry disease : Implication for enzyme replacement therapy.2005

    • Author(s)
      Inagaki, S., Migita, M., Hayakawa, M., Fujita, A., Yoshida, J., Ishizaki, M., Kotani, M., et al.
    • Journal Title

      Journal of Nippon Medical School 72

      Pages: 687-690

    • NAID

      130004146823

    • Data Source
      KAKENHI-PROJECT-16500252
  • [Journal Article] Distal myopathy with rimmed vacuoles : Impaiered-Ο-glycan formation in sarcoemmal glycoprooteins.2005

    • Author(s)
      Tajima, Y., Uyama, E., Go, S., Sato, C., Tao, N., Kotani, M.et al.
    • Journal Title

      American Journal of Pathology 166

      Pages: 1121-1130

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16500252
  • [Journal Article] Distal myopathy with rimmed vacuoles : Impaired O-glycan formation in sarcolemmal glycoproteins.2005

    • Author(s)
      Tajima, Y, Uyama, E., Go, S., Sato, C., Tao, N., Kotani, M., et al.
    • Journal Title

      American Journal of Pathology 166(4)

      Pages: 1121-1130

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16500252
  • [Journal Article] An asymptomatic heterozygous female with Fabry disease : Implication for enzyme replacement therapy.2005

    • Author(s)
      Inagaki, S., Migita, M., Hayakawa, M., fujita, A., Yoshida, J., Ishizaki, M., Kotani, M.et al.
    • Journal Title

      Journal of Nippon Medical School 72

      Pages: 687-690

    • NAID

      130004146823

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16500252
  • [Journal Article] An asymptomatic heterozygous female with Fabry disease : Implication for enzyme replacement therapy.2005

    • Author(s)
      Inagaki, S., Migita, M., Hayakawa, M., Fujita, A., Yoshida, J., Ishizaki, M., Kotani, M., et al.
    • Journal Title

      Journal of Nippon Medical School 72(6)

      Pages: 687-690

    • NAID

      130004146823

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16500252
  • [Journal Article] Cytochemical and biochemical detection of intracellularly accumulate sialyl glycoconjugates in sialidosis and galactosialidosis fibroblasts with Macckia amurensis.2004

    • Author(s)
      Motegi, A., Fujimoto, J., Kotani, N.et al.
    • Journal Title

      Clinica Chimica Acta 344

      Pages: 131-135

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16500252
  • [Journal Article] ALK receptor tyrosine kinase promotes cell growth and neurite outgrowth as revealed by an agonist anti-ALK monoclonal antibody.2004

    • Author(s)
      Motegi, A., Fujimoto, J., Kotani, M., et al.
    • Journal Title

      Journal cell Science 117

      Pages: 3319-3329

    • Data Source
      KAKENHI-PROJECT-16500252
  • [Journal Article] Cytochemical and biochemical detection of intracellularly accumulate sialyl glycoconjugates in sialidosis and galactosialidosis fibroblasts with Macckia amurensis.2004

    • Author(s)
      Kotani, M., Yamada, H., Sakuraba, H.
    • Journal Title

      Clinica Chimica Acta 344

      Pages: 131-135

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16500252
  • [Journal Article] Reversibility versus persistence of GPIIb/IIIa blocker-induced conformational change of GP_<IIb>/III_a (αIIbβ3, CD41/CD61).2004

    • Author(s)
      Schwarz, M., Katagiri, Y, Kotani, M., et al.
    • Journal Title

      Journal of Pharmacology and Experimental Therapeutics 308(3)

      Pages: 1002-1011

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16500252
  • [Journal Article] ALK receptor tyrosine kinase promotes cell growth and neurite outgrowth.2004

    • Author(s)
      Motegi, A., Fujimoto, J., Kotani, N.et al.
    • Journal Title

      Journal of Cell Science 117

      Pages: 3319-3329

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16500252
  • [Journal Article] Clinical and biochemical studies on a Japanese Salla disease case associated with a renal disorder.2004

    • Author(s)
      Ishiwari, K., Kotani, M., et al.
    • Journal Title

      Journal Human Genetics 49

      Pages: 656-663

    • Data Source
      KAKENHI-PROJECT-16500252
  • [Journal Article] Cytochemical and biochemical detection of intracellularly accumulated sialyl glycoconjugates in Sialidosis and galactosialidosis fibroblasts with Maackia amurensis.2004

    • Author(s)
      Kotani, M., Yamada, H., Sakuraba, H.
    • Journal Title

      Clinical and Chimical Acta 344

      Pages: 131-135

    • Data Source
      KAKENHI-PROJECT-16500252
  • [Journal Article] Structure and immunocytochemical studies on α-N-acetylgalactosaminidase deficiency (shindler/Kanzaki desease).2004

    • Author(s)
      Sakuraba, H., Matsuzawa, F., Aikawa, S., Doi, Y., Kotani, M., et al.
    • Journal Title

      Journal Human Genetics 49

      Pages: 1-8

    • Data Source
      KAKENHI-PROJECT-16500252
  • [Journal Article] Distal myopathy with rimmed vacuoles : Impaired O-glycan formation in saroolemmal glycoproteins.2004

    • Author(s)
      Tajima, Y., Uyama, E., Go, S., Sato, C., Tao, N., Kotani, M., et al.
    • Journal Title

      American Journal of Pathology (in press)

    • Data Source
      KAKENHI-PROJECT-16500252
  • [Journal Article] ALK receptor tyrosine kinase promotes cell growth and neurite outgrowth.2004

    • Author(s)
      Motegi, A., Fujimoto, J., Kotani, M, Sakuraba, H., Yamamoto, T.
    • Journal Title

      Journal of Cell Science 117

      Pages: 3319-3329

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16500252
  • [Journal Article] Reversibility versus persistence of GPIIb/IIIa blocker-induced conformational change of GP_IIb/III_a (aIIbβ3,CD41/CD61)2004

    • Author(s)
      Schwarz, M., Katagiri, Y., Kotani, M.et al.
    • Journal Title

      Journal of Pharmacology and Experimental Therapeutics 308

      Pages: 1002-1011

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16500252
  • 1.  MIYASAKA Masayuki (50064613)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 2.  TAMATANI Takuya (70207231)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  KITAMURA Fujiko (90124453)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  通堂 満 (40197645)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  遠山 典子 (30217468)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  SAKURABA Hitoshi (60114493)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  FUJISHIRO Issei (00181347)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  ITOH Kohji (00184656)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  KUBO Hideo (50178034)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  YAMAGUCHI Kazuhito (40034988)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  佐藤 功栄 (40124458)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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