KOTANI Masaharu 小谷政晴

… Alternative Names

KOTANI Masahary 小谷政晴

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Researcher Number	10195737
Affiliation (based on the past Project Information) *help	2005: Ohu University, Pharmaceutical Sciences, Associate Professor, 薬学部, 助教授 2002 – 2004: 財団法人東京都医学研究機構, 東京都臨床医学総合研究所, 研究員 2003: 財)東京都医学研究機構, 東京都臨床医学総合研究所, 研究員 1995: 財団法人東京都臨床医学総合研究所, 腫瘍免疫研究部門, 研究員 1995: The Tokyo Metropolitan Institute of Medical Science, Department of Tumor Immunol, 臨床遺伝学研究部門, 研究員 1994: 財団法人東京都臨床医学総合研究所, 腫瘍免疫研究部門, 研究員 1989 – 1990: Tokyo Metropol.Inst.Med.Sci., Dept.Imm., Research member, 免疫研究部門, 研究員
Review Section/Research Field	Principal Investigator Neurochemistry/Neuropharmacology / Neurochemistry/Neuropharmacology Except Principal Investigator Immunology / Pediatrics
Keywords	Principal Investigator RANDAM-2 / FACS analysis / cell membrane antigens / neural stem cells / マウス / 神経細胞分化 / Mouse neurospheres / 中枢神経系 / 神経幹細胞 / FAGS analysis … More / mouse neurospheres / Gene cloning / P19 EC cells / Mouse / Monoclonal antibody / Cell surface antigen / Neuronal cell differentiation / 遺伝子クローニング / P19EC細胞 / モノクローナル抗体 / 細胞表面抗原 … More Except Principal Investigator 遺伝子導入 / ウサギ / CD4 / HIV / エイズ / Immunomodulation / Adhesion molecule / Cell adhesion / Endothelial cell / Homing / Lymphocyte recirculation / Lymphocyte / ホーミング / 接着因子 / 免疫調節 / 接着分子 / 細胞接着 / 内皮細胞 / ホ-ミング / 再循環現象 / リンパ球 / confocal laser scanning microscopy / Three-dimensional images / Volume visualization / Fabry disease / Metachromatic leukodystrophy / Lipidosis / 脳MRI / 異染性脳白質ジストロフィー / ボリュームビジュアライゼーション / レーザー走査型共焦点顕微鏡 / 副腎白質ジストロフィー / 3次元像再構築 / 3次元画像 / ボリューム・ビジュアライゼーション / Fabry病 / 異染性白質ジストロフィー / リピドーシス / 細胞免疫 Less

Cell biological study of the RANDAM-2 high positive cells and RANDAM-2 low/negative cells in mouse central nervous system.Principal Investigator
- Principal Investigator
  
  KOTANI Masaharu
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Ohu University
  Tokyo Metropolitan Organization for Medical Research
cDNA cloning of cell membrane surface antigens involved in the neuronal differentiation and identification of the antigen positive cells in mouse cerebrumPrincipal Investigator
- Principal Investigator
  
  KOTANI Masaharu
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
Three-dimensional imaging of cells and tissues for the clarification of pathogenesis of inherited metabolic diseases.
- Principal Investigator
  
  SAKURABA Hitoshi
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  The Tokyo Metropolitan Institute of Medical Science
新しい実験的HIV感染in vitroおよびin vivoモデルの作製
- Principal Investigator
  
  宮坂昌之
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
新しい実験的エイズ感染in vitroおよびin vivoモデルの作製
- Principal Investigator
  
  MIYASAKA Masayuki
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
Investigation on receptor systems mediating lymphocyte recirculation
- Principal Investigator
  
  MIYASAKA Masayuki
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Tokyo Metropolitan Institute of Medical Science

All 2005 2004

All Journal Article

[Journal Article] Establishment of immortalized Schwann cells from Sandhoff mice and corrective effect of recombinant human beta-hexosaminidase A on the accumulated GM2 ganglioside.2005
- Author(s)
  Murata, M., Kotani, M., et al.
- Journal Title
  
  Journal of Human Genetics 50
  
  Pages: 460-467
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16500252
[Journal Article] Distal myopathy with rimmed vacuoles : Impaired O-glycan formation in sarcolemmal glycoproteins.2005
- Author(s)
  Tajima, Y., Uyama, E., Go, S., Sato, C., Tao, N., Kotani, M., et al.
- Journal Title
  
  American Journal of Pathology 166
  
  Pages: 1121-1130
- Data Source
  KAKENHI-PROJECT-16500252
[Journal Article] An asymptomatic heterozygous female with Fabry disease : Implication for enzyme replacement therapy.2005
- Author(s)
  Inagaki, S., Migita, M., Hayakawa, M., Fujita, A., Yoshida, J., Ishizaki, M., Kotani, M., et al.
- Journal Title
  
  Journal of Nippon Medical School 72
  
  Pages: 687-690
- NAID
  130004146823
- Data Source
  KAKENHI-PROJECT-16500252
[Journal Article] Distal myopathy with rimmed vacuoles : Impaiered-Ο-glycan formation in sarcoemmal glycoprooteins.2005
- Author(s)
  Tajima, Y., Uyama, E., Go, S., Sato, C., Tao, N., Kotani, M.et al.
- Journal Title
  
  American Journal of Pathology 166
  
  Pages: 1121-1130
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16500252
[Journal Article] Distal myopathy with rimmed vacuoles : Impaired O-glycan formation in sarcolemmal glycoproteins.2005
- Author(s)
  Tajima, Y, Uyama, E., Go, S., Sato, C., Tao, N., Kotani, M., et al.
- Journal Title
  
  American Journal of Pathology 166(4)
  
  Pages: 1121-1130
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16500252
[Journal Article] An asymptomatic heterozygous female with Fabry disease : Implication for enzyme replacement therapy.2005
- Author(s)
  Inagaki, S., Migita, M., Hayakawa, M., fujita, A., Yoshida, J., Ishizaki, M., Kotani, M.et al.
- Journal Title
  
  Journal of Nippon Medical School 72
  
  Pages: 687-690
- NAID
  130004146823
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16500252
[Journal Article] An asymptomatic heterozygous female with Fabry disease : Implication for enzyme replacement therapy.2005
- Author(s)
  Inagaki, S., Migita, M., Hayakawa, M., Fujita, A., Yoshida, J., Ishizaki, M., Kotani, M., et al.
- Journal Title
  
  Journal of Nippon Medical School 72(6)
  
  Pages: 687-690
- NAID
  130004146823
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16500252
[Journal Article] Cytochemical and biochemical detection of intracellularly accumulate sialyl glycoconjugates in sialidosis and galactosialidosis fibroblasts with Macckia amurensis.2004
- Author(s)
  Motegi, A., Fujimoto, J., Kotani, N.et al.
- Journal Title
  
  Clinica Chimica Acta 344
  
  Pages: 131-135
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16500252
[Journal Article] ALK receptor tyrosine kinase promotes cell growth and neurite outgrowth as revealed by an agonist anti-ALK monoclonal antibody.2004
- Author(s)
  Motegi, A., Fujimoto, J., Kotani, M., et al.
- Journal Title
  
  Journal cell Science 117
  
  Pages: 3319-3329
- Data Source
  KAKENHI-PROJECT-16500252
[Journal Article] Cytochemical and biochemical detection of intracellularly accumulate sialyl glycoconjugates in sialidosis and galactosialidosis fibroblasts with Macckia amurensis.2004
- Author(s)
  Kotani, M., Yamada, H., Sakuraba, H.
- Journal Title
  
  Clinica Chimica Acta 344
  
  Pages: 131-135
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16500252
[Journal Article] Reversibility versus persistence of GPIIb/IIIa blocker-induced conformational change of GP_<IIb>/III_a (αIIbβ3, CD41/CD61).2004
- Author(s)
  Schwarz, M., Katagiri, Y, Kotani, M., et al.
- Journal Title
  
  Journal of Pharmacology and Experimental Therapeutics 308(3)
  
  Pages: 1002-1011
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16500252
[Journal Article] ALK receptor tyrosine kinase promotes cell growth and neurite outgrowth.2004
- Author(s)
  Motegi, A., Fujimoto, J., Kotani, N.et al.
- Journal Title
  
  Journal of Cell Science 117
  
  Pages: 3319-3329
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16500252
[Journal Article] Clinical and biochemical studies on a Japanese Salla disease case associated with a renal disorder.2004
- Author(s)
  Ishiwari, K., Kotani, M., et al.
- Journal Title
  
  Journal Human Genetics 49
  
  Pages: 656-663
- Data Source
  KAKENHI-PROJECT-16500252
[Journal Article] Cytochemical and biochemical detection of intracellularly accumulated sialyl glycoconjugates in Sialidosis and galactosialidosis fibroblasts with Maackia amurensis.2004
- Author(s)
  Kotani, M., Yamada, H., Sakuraba, H.
- Journal Title
  
  Clinical and Chimical Acta 344
  
  Pages: 131-135
- Data Source
  KAKENHI-PROJECT-16500252
[Journal Article] Structure and immunocytochemical studies on α-N-acetylgalactosaminidase deficiency (shindler/Kanzaki desease).2004
- Author(s)
  Sakuraba, H., Matsuzawa, F., Aikawa, S., Doi, Y., Kotani, M., et al.
- Journal Title
  
  Journal Human Genetics 49
  
  Pages: 1-8
- Data Source
  KAKENHI-PROJECT-16500252
[Journal Article] Distal myopathy with rimmed vacuoles : Impaired O-glycan formation in saroolemmal glycoproteins.2004
- Author(s)
  Tajima, Y., Uyama, E., Go, S., Sato, C., Tao, N., Kotani, M., et al.
- Journal Title
  
  American Journal of Pathology (in press)
- Data Source
  KAKENHI-PROJECT-16500252
[Journal Article] ALK receptor tyrosine kinase promotes cell growth and neurite outgrowth.2004
- Author(s)
  Motegi, A., Fujimoto, J., Kotani, M, Sakuraba, H., Yamamoto, T.
- Journal Title
  
  Journal of Cell Science 117
  
  Pages: 3319-3329
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16500252
[Journal Article] Reversibility versus persistence of GPIIb/IIIa blocker-induced conformational change of GP_IIb/III_a (aIIbβ3,CD41/CD61)2004
- Author(s)
  Schwarz, M., Katagiri, Y., Kotani, M.et al.
- Journal Title
  
  Journal of Pharmacology and Experimental Therapeutics 308
  
  Pages: 1002-1011
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16500252

1. MIYASAKA Masayuki (50064613)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. TAMATANI Takuya (70207231)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. KITAMURA Fujiko (90124453)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. 通堂満 (40197645)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 遠山典子 (30217468)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. SAKURABA Hitoshi (60114493)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. FUJISHIRO Issei (00181347)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. ITOH Kohji (00184656)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. KUBO Hideo (50178034)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. YAMAGUCHI Kazuhito (40034988)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 佐藤功栄 (40124458)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KOTANI Masaharu 小谷 政晴

KOTANI Masahary 小谷 政晴

Research Projects

Research Products

Co-Researchers

Cell biological study of the RANDAM-2 high positive cells and RANDAM-2 low/negative cells in mouse central nervous system.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

cDNA cloning of cell membrane surface antigens involved in the neuronal differentiation and identification of the antigen positive cells in mouse cerebrumPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Three-dimensional imaging of cells and tissues for the clarification of pathogenesis of inherited metabolic diseases.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

新しい実験的HIV感染in vitroおよびin vivoモデルの作製

Principal Investigator

Project Period (FY)

Research Category

Research Institution

新しい実験的エイズ感染in vitroおよびin vivoモデルの作製

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Investigation on receptor systems mediating lymphocyte recirculation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Establishment of immortalized Schwann cells from Sandhoff mice and corrective effect of recombinant human beta-hexosaminidase A on the accumulated GM2 ganglioside.2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Distal myopathy with rimmed vacuoles : Impaired O-glycan formation in sarcolemmal glycoproteins.2005

Author(s)

Journal Title

Data Source

[Journal Article] An asymptomatic heterozygous female with Fabry disease : Implication for enzyme replacement therapy.2005

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Distal myopathy with rimmed vacuoles : Impaiered-Ο-glycan formation in sarcoemmal glycoprooteins.2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Distal myopathy with rimmed vacuoles : Impaired O-glycan formation in sarcolemmal glycoproteins.2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] An asymptomatic heterozygous female with Fabry disease : Implication for enzyme replacement therapy.2005

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] An asymptomatic heterozygous female with Fabry disease : Implication for enzyme replacement therapy.2005

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] Cytochemical and biochemical detection of intracellularly accumulate sialyl glycoconjugates in sialidosis and galactosialidosis fibroblasts with Macckia amurensis.2004

Author(s)

Journal Title

Description

Data Source

KOTANI Masaharu 小谷政晴

KOTANI Masahary 小谷政晴