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Toda Masaaki  戸田 雅昭

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TODA Masaaki  戸田 雅昭

戸田 雅昭  トダ マサアキ

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Researcher Number 10202201
Affiliation (Current) 2025: 三重大学, 医学系研究科, 准教授
Affiliation (based on the past Project Information) *help 2016 – 2024: 三重大学, 医学系研究科, 講師
2015: 三重大学, 医学(系)研究科(研究院), 講師
2011 – 2013: 三重大学, 医学(系)研究科(研究院), 講師
1996: 東京都老人総合研究所, 免疫病理部門, 研究員
1993 – 1994: 理化学研究所, 真核生物研究室, 奨励研究生
Review Section/Research Field
Principal Investigator
遺伝
Except Principal Investigator
Basic Section 53030:Respiratory medicine-related / Respiratory organ internal medicine / Basic Section 53010:Gastroenterology-related / 膠原病・アレルギー・感染症内科学 / Experimental pathology
Keywords
Principal Investigator
RT-PCR / 自己免疫病 / ヘルパーT細胞 / T細胞抗原レセプター / 自己免疫
Except Principal Investigator
細菌叢 / コリシン / corisin / トランスジェニックマウス / 急性肺障害 … More / アポトーシス / 肺内細菌叢 / 細胞死 / 成長因子 / TGFbeta1 / MUC5B / サイトカイン / ブレオマイシン / ムチン / 肺線維症 / マウスモデル / 遺伝子変異 / 免疫制御 / T細胞 / 自己免疫病 / 急性肺炎 / SARS-CoV-2 / 凝固制御機構 / 凝固系 / COVID-19 / 肝線維化 / 抗corisin抗体 / 呼吸不全 / 肺気腫 / ELISA法 / COPD / 肺疾患 / ムチン過剰発現 / 細胞死誘導因子 / TGFΒ1 / MUC5Bタンパク / 抗コリシン抗体 / 細胞死因子 / 急性増悪 / 予後 / 抗線維化剤 / 肺傷害 / 遺伝子改変マウス / rs35705950単塩基多型 / コラーゲン / ケモカイン / PCR成長因子 / トランジェニックマウス / 肺癌マウスモデル / 耐性 / 上皮細胞成長因子受容体 / 耐性克服 / TKI耐性 / NF-κB / Akt経路 / 癌 / 腺癌 / バイオマーカー / 免疫チェックポイント分子 / EGFR遺伝子 / 肺癌 / 治療耐性 / 核酸薬品 / 転写因子 / 分子標的治療 / 非小細胞肺癌 / チロシンキナーゼ阻害剤 / 細胞膜貫通受容体 / TGF-β1 / 喘息 / TGF-β1 / 上皮間葉移行 / airway remodeling / eosinophils / Bronchial asthma / 上皮間葉間移行 / 気道リモデリング / 好酸球 / 気管支喘息 / T細胞性制御 / 免疫的自己寛容 Less
  • Research Projects

    (11 results)
  • Research Products

    (56 results)
  • Co-Researchers

    (18 People)
  •  細菌叢由来ペプチドのNASH肝線維化における意義解明と臨床応用への展開

    • Principal Investigator
      安間 太郎
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Mie University
  •  Development of a new treatment for COVID-19-related acute lung injury targeting the microbiota-derived peptide corisin

    • Principal Investigator
      Gabazza Esteban
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53030:Respiratory medicine-related
    • Research Institution
      Mie University
  •  The role of the lung microbiota-derived proapoptotic peptide (corisin) in COPD

    • Principal Investigator
      GABAZZA CORINA
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53030:Respiratory medicine-related
    • Research Institution
      Mie University
  •  Investigating the role of mucin in pulmonary fibrosis-associated microbiota dysbiosis using MUC5B overexpressing mice

    • Principal Investigator
      Gabazza Esteban
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53030:Respiratory medicine-related
    • Research Institution
      Mie University
  •  Development of novel therapeutic approaches for pulmonary fibrosis using MUC5B overexpressing mice

    • Principal Investigator
      Taguchi Osamu
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Mie University
  •  Development of new therapy for lung cancer using genetically modified transgenic mice

    • Principal Investigator
      Gabazza Esteban
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Mie University
  •  Investigation of mechanisms of airway remodeling responsible for severe bronchial asthma: possible involvement of epithelial mesenchymal transition

    • Principal Investigator
      FUJISAWA Takao
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      独立行政法人国立病院機構三重病院(臨床研究部)
  •  自己免疫病発症の分子機構:自己反応性T細胞の制御機構について

    • Principal Investigator
      坂口 志文
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo Metropolitan Institute of Gerontology
  •  発生工学的手法による自己免疫病発症機構の解析

    • Principal Investigator
      坂口 志文
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      Tokyo Metropolitan Institute of Gerontology
  •  単一細胞レベルでのmRNA分析によるヘルパーT細胞の機能解析Principal Investigator

    • Principal Investigator
      戸田 雅昭
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      遺伝
    • Research Institution
      The Institute of Physical and Chemical Research
  •  マウス自己免疫病モデルにおける自己反応性T細胞抗原レセプターの特性Principal Investigator

    • Principal Investigator
      戸田 雅昭
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      遺伝
    • Research Institution
      The Institute of Physical and Chemical Research

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011

All Journal Article Presentation

  • [Journal Article] Amelioration of Pulmonary Fibrosis by Matrix Metalloproteinase-2 Overexpression.2023

    • Author(s)
      Inoue R, Yasuma T, Fridman D'Alessandro V, Toda M, Ito T, Tomaru A, D'Alessandro-Gabazza CN, Tsuruga T, Okano T, Takeshita A, Nishihama K, Fujimoto H, Kobayashi T, Gabazza EC.
    • Journal Title

      Int J Mol Sci.

      Volume: 24(7) Issue: 7 Pages: 6695-6695

    • DOI

      10.3390/ijms24076695

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K15206, KAKENHI-PROJECT-23K07651, KAKENHI-PROJECT-21K08203
  • [Journal Article] Inhibition of a Microbiota-Derived Peptide Ameliorates Established Acute Lung Injury2023

    • Author(s)
      D'Alessandro Fridman V, D'Alessandro-Gabazza CN, Yasuma T, Toda M, Takeshita A, Tomaru A, Tharavecharak S, Lasisi IO, Hess RY, Nishihama K, Fujimoto H, Kobayashi T, Cann I, Gabazza EC.
    • Journal Title

      American Journal of Pathology

      Volume: 23 Issue: 6 Pages: 740-754

    • DOI

      10.1016/j.ajpath.2023.03.003

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K08280, KAKENHI-PROJECT-20K08564, KAKENHI-PROJECT-21K16116, KAKENHI-PROJECT-21K16160, KAKENHI-PROJECT-23K15206, KAKENHI-PROJECT-21K08203, KAKENHI-PROJECT-21K16185
  • [Journal Article] Is Helicobacter pylori infection inversely correlated with atopic, skin, and autoimmune diseases?2022

    • Author(s)
      Yasuma T, D'Alessandro-Gabazza CN, Fujimoto H, Kobayashi T, Imoto I, Gabazza EC.
    • Journal Title

      Allergy

      Volume: 77 Issue: 10 Pages: 3165-3166

    • DOI

      10.1111/all.15306

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K08280, KAKENHI-PROJECT-20K08564
  • [Journal Article] Transforming Growth Factorβ1 Overexpression Is Associated with Insulin Resistance and Rapidly Progressive Kidney Fibrosis under Diabetic Conditions.2022

    • Author(s)
      D'Alessandro VF, Takeshita A, Yasuma T, Toda M, D'Alessandro-Gabazza CN, Okano Y, Tharavecharak S, Inoue C, Nishihama K, Fujimoto H, Kobayashi T, Yano Y, Gabazza EC.
    • Journal Title

      Int J Mol Sci.

      Volume: 23 Issue: 22 Pages: 146251-19

    • DOI

      10.3390/ijms232214265

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K08256, KAKENHI-PROJECT-22K08280, KAKENHI-PROJECT-21K16185, KAKENHI-PROJECT-21K16160
  • [Journal Article] Inhibition of lung microbiota-derived proapoptotic peptides ameliorates acute exacerbation of pulmonary fibrosis.2022

    • Author(s)
      D'Alessandro-Gabazza CN, Yasuma T, Kobayashi T, Toda M, Abdel-Hamid AM, Fujimoto H, Hataji O, Nakahara H, Takeshita A, Nishihama K, Okano T, Saiki H, Okano Y, Tomaru A, D'Alessandro VF, Shiraishi M, Mizoguchi A, Ono R, Ohtsuka J, Fukumura M, Nosaka T, et al. & Gabazza EC
    • Journal Title

      Nat Commun

      Volume: 13 Issue: 1 Pages: 1558-1558

    • DOI

      10.1038/s41467-022-29064-3

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03529, KAKENHI-PROJECT-20K08564, KAKENHI-PROJECT-21K08256, KAKENHI-PROJECT-21K08411, KAKENHI-PROJECT-20K21614, KAKENHI-PROJECT-21K08203, KAKENHI-PROJECT-21K16185, KAKENHI-PROJECT-21K16116, KAKENHI-PROJECT-21K16160
  • [Journal Article] A Microbiome-Derived Peptide Induces Apoptosis of Cells from Different Tissues2021

    • Author(s)
      Saiki Haruko、Okano Yuko、Yasuma Taro、Toda Masaaki、Takeshita Atsuro、Abdel-Hamid Ahmed M.、Fridman D’Alessandro Valeria、Tsuruga Tatsuki、D’Alessandro-Gabazza Corina N.、Katayama Kan、Sugimoto Masahiko、Fujimoto Hajime、Yamanaka Keiichi、Kobayashi Tetsu、Cann Isaac、Gabazza Esteban C.
    • Journal Title

      Cells

      Volume: 10 Issue: 11 Pages: 2885-2885

    • DOI

      10.3390/cells10112885

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08564, KAKENHI-PROJECT-21K08203, KAKENHI-PROJECT-21K16185
  • [Journal Article] Low-Dose of Intrapulmonary Pirfenidone Improves Human Transforming Growth Factorβ1-Driven Lung Fibrosis2020

    • Author(s)
      Okano Tomohito、Kobayashi Tetsu、Yasuma Taro、D’Alessandro-Gabazza Corina N.、Toda Masaaki、Fujimoto Hajime、Nakahara Hiroki、Okano Yuko、Takeshita Atsuro、Nishihama Kota、Saiki Haruko、Tomaru Atsushi、Fridman D’Alessandro Valeria、Ishida Satoru、Sugimoto Hiromi、Takei Yoshiyuki、Gabazza Esteban C.
    • Journal Title

      Frontiers in Pharmacology

      Volume: 11

    • DOI

      10.3389/fphar.2020.593620

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08564, KAKENHI-PROJECT-18K08175
  • [Journal Article] Protein S is Protective in Acute Lung Injury by Inhibiting Cell Apoptosis2019

    • Author(s)
      Baffour Tonto Prince、Yasuma Taro、Kobayashi Tetsu、D’Alessandro-Gabazza Corina、Toda Masaaki、Saiki Haruko、Fujimoto Hajime、Asayama Kentaro、Fujiwara Kentaro、Nishihama Kota、Okano Tomohito、Takeshita Atsuro、Gabazza Esteban
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 20 Issue: 5 Pages: 1082-1082

    • DOI

      10.3390/ijms20051082

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08442, KAKENHI-PROJECT-17K09611
  • [Journal Article] Protective Role of Matrix Metalloproteinase-2 in Allergic Bronchial Asthma.2019

    • Author(s)
      Takahashi Y, Kobayashi T, D'Alessandro-Gabazza CN, Toda M, Fujiwara K, Okano T, Fujimoto H, Asayama K, Takeshita A, Yasuma T, Nishihama K, Inoue R, Qin L,Takei Y, Taguchi O, Gabazza EC.
    • Journal Title

      Front Immunol.

      Volume: 10 Pages: 1795-1795

    • DOI

      10.3389/fimmu.2019.01795

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08175, KAKENHI-PROJECT-19K17738, KAKENHI-PROJECT-19K17960, KAKENHI-PROJECT-17K08442, KAKENHI-PROJECT-17K09611
  • [Journal Article] Protein S Exacerbates Chronic Liver Injury and Fibrosis2018

    • Author(s)
      Totoki Toshiaki、D' Alessandro-Gabazza Corina N.、Toda Masaaki、Tonto Prince Baffour、Takeshita Atsuro、Yasuma Taro、Nishihama Kota、Iwasa Motoh.、Horiki Noriyuki、Takei Yoshiyuki、Gabazza Esteban C.
    • Journal Title

      Am J Pathol

      Volume: 印刷中 Issue: 5 Pages: 1195-1203

    • DOI

      10.1016/j.ajpath.2018.01.007

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08442, KAKENHI-PROJECT-15K09170
  • [Journal Article] Anti-apoptotic activity of human matrix metalloproteinase-2 attenuates diabetes mellitus2018

    • Author(s)
      Nishihama Kota、Yasuma Taro、Yano Yutaka、D' Alessandro-Gabazza Corina N.、Toda Masaaki、Hinneh Josephine A.、Baffour Tonto Prince、Takeshita Atsuro、Totoki Toshiaki、Mifuji-Moroka Rumi、Kobayashi Tetsu、Iwasa Motoh、Takei Yoshiyuki、Morser John、Cann Isaac、Gabazza Esteban C.
    • Journal Title

      Metabolism

      Volume: 82 Pages: 88-99

    • DOI

      10.1016/j.metabol.2018.01.016

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09824, KAKENHI-PROJECT-17K08442, KAKENHI-PROJECT-15K09170
  • [Journal Article] The medicinal mushroom Grifola Gargal ameliorates Allergic bronchial asthma2018

    • Author(s)
      Harada, E., D’Alessandro-Gabazza, C. N., Toda, M., Morizono, T., Totoki, T., Yasuma, T., Nishihama, K., Kobayashi, T. Sumiya, Kawagishi, H., and Gabazza. E. C.
    • Journal Title

      J. Med. Food

      Volume: 21 Issue: 2 Pages: 136-145

    • DOI

      10.1089/jmf.2017.4016

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-17H06402, KAKENHI-PROJECT-17K08442, KAKENHI-PROJECT-15K09170
  • [Journal Article] Mice overexpressing latent matrix metalloproteinase-2 develop lung emphysema after short-term exposure to cigarette smoke extract2018

    • Author(s)
      Onishi Masahiro、Kobayashi Tetsu、D'Alessandro-Gabazza Corina N.、Fujimoto Hajime、Chelakkot-Govindalayathil Ayshwarya-Lakshmi、Takahashi Yoshinori、Yasuma Taro、Nishihama Kota、Toda Masaaki、Takei Yoshiyuki、Taguchi Osamu、Gabazza Esteban C.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 497 Issue: 1 Pages: 332-338

    • DOI

      10.1016/j.bbrc.2018.02.081

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08442, KAKENHI-PROJECT-17K09611, KAKENHI-PROJECT-15K09170
  • [Journal Article] Renal Injury during Long-Term Crizotinib Therapy2018

    • Author(s)
      Yasuma Taro、Kobayashi Tetsu、D’Alessandro-Gabazza Corina、Fujimoto Hajime、Ito Kentaro、Nishii Yoichi、Nishihama Kota、Baffour Tonto Prince、Takeshita Atsuro、Toda Masaaki、Gabazza Esteban、Taguchi Osamu、Yonemura Shigenori、Hataji Osamu
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 19 Issue: 10 Pages: 2902-2902

    • DOI

      10.3390/ijms19102902

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08442, KAKENHI-PROJECT-17K09611
  • [Journal Article] Identification of Halophilic Microbes in Lung Fibrotic Tissue by Oligotyping2018

    • Author(s)
      D’Alessandro-Gabazza Corina N.、Méndez-García Celia、Hataji Osamu、Westergaard Sara、Watanabe Fumiaki、Yasuma Taro、Toda Masaaki、Fujimoto Hajime、Nishihama Kota、Fujiwara Kentaro、Taguchi Osamu、Kobayashi Tetsu、Mackie Roderick I.、Cann Isaac、Gabazza Esteban C.
    • Journal Title

      Frontiers in Microbiology

      Volume: 9 Pages: 1892-1892

    • DOI

      10.3389/fmicb.2018.01892

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08175, KAKENHI-PROJECT-17K08442, KAKENHI-PROJECT-17K09611
  • [Journal Article] Inhibition of Cell Apoptosis and Amelioration of Pulmonary Fibrosis by Thrombomodulin2017

    • Author(s)
      Fujiwara Kentaro、Kobayashi Tetsu、Fujimoto Hajime、Nakahara Hiroki、D'Alessandro-Gabazza Corina N.、Hinneh Josephine A.、Takahashi Yoshinori、Yasuma Taro、Nishihama Kota、Toda Masaaki、Kajiki Masahiro、Takei Yoshiyuki、Taguchi Osamu、Gabazza Esteban C.
    • Journal Title

      Am J Pathol

      Volume: 187 Issue: 10 Pages: 2312-2322

    • DOI

      10.1016/j.ajpath.2017.06.013

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08442, KAKENHI-PROJECT-17K09611, KAKENHI-PROJECT-15K09170
  • [Journal Article] Efficacy of osimertinib in a patient with non-small cell lung cancer harboring epithelial growth factor receptor exon 19 deletion/T790M mutation, with poor performance status2017

    • Author(s)
      Nishii Yoichi、Hataji Osamu、Ito Kentaro、Watanabe Fumiaki、Kobayashi Tetsu、D'alessandro-Gabazza Corina、Toda Masaaki、Taguchi Osamu、Yamamoto Nobuyuki、Gabazza Esteban
    • Journal Title

      Mol Clin Oncol

      Volume: 8 Pages: 246-249

    • DOI

      10.3892/mco.2017.1522

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08442, KAKENHI-PROJECT-17K09611, KAKENHI-PROJECT-15K09170
  • [Journal Article] β2 adrenergic agonist suppresses eosinophil-induced epithelial-to-mesenchymal transition of bronchial epithelial cells2017

    • Author(s)
      Kainuma K, Kobayashi T, D'Alessandro-Gabazza CN, Toda M, Yasuma T, Nishihama K, Fujimoto H, Kuwabara Y, Hosoki K, Nagao M, Fujisawa T, Gabazza EC
    • Journal Title

      Respir Res

      Volume: 18 Issue: 1 Pages: 79-79

    • DOI

      10.1186/s12931-017-0563-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08442, KAKENHI-PROJECT-15K09170
  • [Journal Article] Interleukin-33 induces mucin gene expression and goblet cell hyperplasia in human nasal epithelial cells.2017

    • Author(s)
      Ishinaga H, et al
    • Journal Title

      Cytokine

      Volume: 90 Pages: 60-65

    • DOI

      10.1016/j.cyto.2016.10.010

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462578, KAKENHI-PROJECT-15K09170
  • [Journal Article] Low dose of alcohol attenuates pro-atherosclerotic activity of thrombin2017

    • Author(s)
      Toda Masaaki、Totoki Toshiaki、Nakamura Chizu、Yasuma Taro、D' Alessandro-Gabazza Corina N.、Mifuji-Moroka Rumi、Nishihama Kota、Iwasa Motoh、Horiki Noriyuki、Gabazza Esteban C.、Takei Yoshiyuki
    • Journal Title

      Atherosclerosis

      Volume: 265 Pages: 215-224

    • DOI

      10.1016/j.atherosclerosis.2017.09.005

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09170
  • [Journal Article] Oligonucleotide-targeting periostin ameliorates pulmonary fibrosis2017

    • Author(s)
      Tomaru A、Kobayashi T、Hinneh J A、Baffour Tonto P、D'Alessandro-Gabazza C N、Fujimoto H、Fujiwara K、Takahashi Y、Ohnishi M、Yasuma T、Nishihama K、Yoshino M、Takao K、Toda M、Totoki T、Takei Y、Yoshikawa K、Taguchi O、Gabazza E C
    • Journal Title

      Gene Ther

      Volume: 24 Issue: 11 Pages: 706-716

    • DOI

      10.1038/gt.2017.80

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08442, KAKENHI-PROJECT-17K09611, KAKENHI-PROJECT-15K09170
  • [Journal Article] Amelioration of Diabetes by Protein S. Diabetes.2016

    • Author(s)
      Yasuma T, Yano Y, D'Alessandro-Gabazza CN, Toda M, Gil-Bernabe P, Kobayashi T, Nishihama K, Hinneh JA, Mifuji-Moroka R, Roeen Z, Morser J, Cann I, Motoh I, Takei Y, Gabazza EC
    • Journal Title

      Diabetes

      Volume: 65 Issue: 7 Pages: 1940-1951

    • DOI

      10.2337/db15-1404

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09170
  • [Journal Article] Protein S is protective in pulmonary fibrosis.2016

    • Author(s)
      Urawa M, Kobayashi T, D'Alessandro-Gabazza CN, Fujimoto H, Toda M, Roeen Z, Hinneh JA, Yasuma T, Takei Y, Taguchi O, Gabazza EC
    • Journal Title

      J Thromb Haemost

      Volume: 14 Issue: 8 Pages: 1588-1599

    • DOI

      10.1111/jth.13362

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09170
  • [Journal Article] Activated protein C modulates the proinflammatory activity of dendritic cells.2015

    • Author(s)
      Matsumoto T, Matsushima Y, Toda M, Roeen Z, D'Alessandro-Gabazza CN, Hinneh JA, Harada E, Yasuma T, Yano Y, Urawa M, Kobayashi T, Taguchi O, Gabazza EC.
    • Journal Title

      J Asthma Allergy

      Volume: 8 Pages: 29-37

    • DOI

      10.2147/jaa.s75261

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09170, KAKENHI-PROJECT-25461154, KAKENHI-PROJECT-25461189
  • [Journal Article] Amelioration of Atherosclerosis by the New Medicinal Mushroom Grifola gargal Singer.2015

    • Author(s)
      Harada E, D'Alessandro-Gabazza CN, Toda M, Morizono T, Chelakkot-Govindalayathil AL, Roeen Z, Urawa M, Yasuma T, Yano Y, Sumiya T, Gabazza EC
    • Journal Title

      J Med Food

      Volume: 18 Issue: 8 Pages: 872-881

    • DOI

      10.1089/jmf.2014.3315

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09170
  • [Journal Article] Thrombomodulin inhibits the activation of eosinophils and mast cells.2015

    • Author(s)
      Roeen Z, Toda M, D'Alessandro-Gabazza CN, Onishi M, Kobayashi T, Yasuma T, Urawa M, Taguchi O, Gabazza EC.
    • Journal Title

      Cell Immunol.

      Volume: 293 Issue: 1 Pages: 34-40

    • DOI

      10.1016/j.cellimm.2014.11.005

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25461154, KAKENHI-PROJECT-15K09170, KAKENHI-PROJECT-25461189
  • [Journal Article] Protein S exacerbates alcoholic hepatitis by stimulating liver natural killer T cells.2015

    • Author(s)
      Chelakkot-Govindalayathil AL, Mifuji-Moroka R, D'Alessandro-Gabazza CN, Toda M, Matsuda Y, Gil-Bernabe P, Roeen Z, Yasuma T, Yano Y, Gabazza EC, Iwasa M, Takei Y.
    • Journal Title

      J Thromb Haemost.

      Volume: 13(1) Issue: 1 Pages: 142-154

    • DOI

      10.1111/jth.12789

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24590967, KAKENHI-PROJECT-24591128, KAKENHI-PROJECT-15K09170, KAKENHI-PROJECT-25460990
  • [Journal Article] Montelukast suppresses epithelial to mesenchymal transition of bronchial epithelial cells induced by eosinophils2014

    • Author(s)
      Hosoki K, Kainuma K, Toda M, Harada E, Chelakkot-Govindalayathila AL, Roeen Z, Nagao M, D'Alessandro-Gabazza CN, Fujisawa T, Gabazza EC
    • Journal Title

      BiochemBiophysResCommun

      Volume: 449 Pages: 351-356

    • Data Source
      KAKENHI-PROJECT-23591471
  • [Journal Article] Eosinophils promote epithelial to mesenchymal transition of bronchial epithelial cells2013

    • Author(s)
      Yasukawa A, Hosoki K, Toda M, Miyake Y, Matsushima Y, Matsumoto T, Boveda-Ruiz D, Gil-Bernabe P, Nagao M, Sugimoto M, Hiraguchi Y, Tokuda R, Naito M, Takagi T, D'Alessandro-Gabazza CN, Suga S, Kobayashi T, Fujisawa T, Taguchi O, Gabazza EC
    • Journal Title

      PLoS One

      Volume: 8

    • Data Source
      KAKENHI-PROJECT-23591471
  • [Journal Article] Eosinophils promote epithelial to mesenchymal transition of bronchial epithelial cells.2013

    • Author(s)
      Yasukawa A, Hosoki K, Toda M, Miyake Y, Matsushima Y, Matsumoto T, Boveda-Ruiz D, Gil-Bernabe P, Nagao M, Sugimoto M, Hiraguchi Y, Tokuda R, Naito M, Takagi T, D'Alessandro-Gabazza CN, Suga S, Kobayashi T, Fujisawa T, Taguchi O, Gabazza EC.
    • Journal Title

      PLoS One

      Volume: 8 Issue: 5 Pages: 1-12

    • DOI

      10.1371/journal.pone.0064281

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591471, KAKENHI-PROJECT-24591128, KAKENHI-PROJECT-25461154
  • [Presentation] Thrombomodulin suppresses apoptosis of podocytes by activating Akt signal pathway2021

    • Author(s)
      Valeria Fridman D'Alessandro, Taro Yasuma, Masaaki Toda, Atsuro Takeshita, Corina D'Alessandro Gabazza, Yuko Okano, Yutaka Yano, Esteban Gabazza
    • Organizer
      第50回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-20K08564
  • [Presentation] A microbiome-derived peptide induces apoptosis of cells from different tissues2021

    • Author(s)
      Yuko Okano1, Atsuro Takeshita, Kota Nishihama, Valeria Fridman, Taro Yasuma, Corina Gabazza, Masaaki Toda, Yutaka Yano, Esteban Gabazza
    • Organizer
      第50回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-20K08564
  • [Presentation] Amelioration of kidney fibrosis and dysfunction by recombinant thrombomodulin2021

    • Author(s)
      Asturo Takeshita, Taro Yasuma, Yuko Okano, Kota Nishihama, Valeria Fridman D'Alessandro, Masaaki Toda, Corina N. D'Alessandro-Gabazza, Yutaka Yano, Esteban C. Gabazza
    • Organizer
      第50回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-20K08564
  • [Presentation] Coagulation markers in COPD2018

    • Author(s)
      Gunnar Reksten Husebo, Esteban Gabazza, Corina D'Alessandro, Marianne Aanerud, Masaaki Toda, Rune Gronseth, Per S. Bakke, Tomas Mikal Lind Eagan
    • Organizer
      ERS 2018 International Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09611
  • [Presentation] マウス肺線維化モデルに対するPeriostin抑制効果の検討2018

    • Author(s)
      都丸 敦史、ガバザ エステバン、樋口 友里恵、齋木 晴子、藤原 拓海、浅山 健太郎、岡野 智仁、高橋 佳紀、藤原 研太郎、中原 博紀、藤本 源、戸田 雅昭、ガバザ コリナ、小林 哲
    • Organizer
      第48回吸入療法研究会
    • Data Source
      KAKENHI-PROJECT-17K09611
  • [Presentation] マトリックスメタロプロテアーゼ2遺伝子導入喘息マウスにおける気道病変の解析2017

    • Author(s)
      藤原 研太郎、小林 哲、浅山 健太郎、都丸 敦史、高橋 佳紀、大西 真裕、中原 博紀、藤本 源、西濵 康太、安間 太郎、ガバザ コリナ、戸田 雅昭、ガバザ エステバン、田口 修
    • Organizer
      第66回日本アレルギー学会学術大会
    • Data Source
      KAKENHI-PROJECT-15K09170
  • [Presentation] 気道リモデリングにおけるMMP-2の役割の解明2017

    • Author(s)
      桑原 優、戸田 雅昭、ガバザ コリナ、安間 太郎、貝沼 圭吾、長尾 みづほ、ガバザ エステバン、藤澤 隆夫
    • Organizer
      第66回日本アレルギー学会学術大会
    • Data Source
      KAKENHI-PROJECT-15K09170
  • [Presentation] 気管支喘息におけるmatrix metalloproteinase-2(MMP-2)の変動2017

    • Author(s)
      藤原 研太郎、小林 哲、浅山 健太郎、都丸 敦史、高橋 佳紀、大西 真裕、中原 博紀、藤本 源、ダレッサンドロ ガバザ コリナ、戸田 雅昭、田口 修、ガバザ エステバン
    • Organizer
      第16回Kinki Hokuriku Airway disease Conference
    • Data Source
      KAKENHI-PROJECT-15K09170
  • [Presentation] 気道の線維化の先には発癌があるのか?2017

    • Author(s)
      小林 哲、Esteban C. Gabazza、浦田 健太郎、高橋 佳紀、都丸 敦史、藤原 研太郎、大西 真裕、中原 博紀、藤本 源、Corina N. D’Alessandro-Gabazza、戸田 雅昭、田口 修
    • Organizer
      第36回気道分泌研究会
    • Data Source
      KAKENHI-PROJECT-17K09611
  • [Presentation] Protective Effect of Protein S against the Development of Diabetic Nephropathy in Mice2017

    • Author(s)
      A. Takeshita, K. Nishihama, T. Yasuma, K. Fujiwara, E. Harada, C.N. D’Alessandro-Gabazza, M. Toda, T. Kobayashi, Y. Yano, E.C. Gabazza
    • Organizer
      ISTH Congress and 63rd Annual SSC Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09170
  • [Presentation] 遺伝子改変マウスを用いた糖尿性腎症モデルの作成2017

    • Author(s)
      西濵 康太、安間 太郎、竹下 敦郎、ガバザ コリナ、戸田 雅昭、矢野 裕、ガバザ エステバン
    • Organizer
      第60回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-15K09170
  • [Presentation] TGF-β1によるインスリン抵抗性の誘導in vitroでの検討2017

    • Author(s)
      竹下 敦郎、井上 知紗、真木 加奈子、岡野 優子、佐々木 賢、西濵 康太、橋本 礼、堀田 康広、上村 明、坂本 正子、安間 太郎、大西 悠紀、鈴木 俊成、古田 範子、矢野 裕、戸田 雅昭、ガバザ コリナ、ガバザ エステバン、竹井 謙之
    • Organizer
      第60回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-15K09170
  • [Presentation] Thrombin-activable Fibrinolysis Inhibitor (Procarboxypeptidase B2) Deficiency Protects from Carbon Tetrachloride-induced Liver Fibrosis2017

    • Author(s)
      T. Totoki, C.N. D’Alessandro-Gabazza, R. Mifuji-Moroka, K. Nishihama, A. Takeshita, T. Yasuma, Y. Takahashi, K. Fujiwara, M. Toda, M. Nakamura, N. Horiki, M. Iwasa, T. Kobayashi, Y. Takei, E.C. Gabazza
    • Organizer
      ISTH Congress and 63rd Annual SSC Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09170
  • [Presentation] Overexpression of Protein S Exacerbates Carbon Tetrachloride-induced Liver Injury and Fibrosis in Mice2017

    • Author(s)
      Totoki Toshiaki, D’Alessandro-Gabazza Corina N., Moroka-Mifuji Rumi, Nishihama Kota, Takeshita Atsuro, Yasuma Taro, Takahashi Yoshinori, Fujiwara Kentaro, Toda Masaaki, Iwasa Motoh, Kobayashi Tetsu, Takei Yoshiyuki, and Gabazza-Esteban
    • Organizer
      BIT’s 2nd Annual World Congress of Digestive Disease-2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09170
  • [Presentation] The role of eosinophils and matrix metalloproteinase-2 in airway remondeling2017

    • Author(s)
      Kuwabara Y., Toda M., Yasuma T., Kainuma K., Nagao M., Corina D. N., Esteban G. C., Fujisawa T
    • Organizer
      European Academy of Allergy and Climical Immunology EAACI Congress 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09170
  • [Presentation] 気管支喘息患者におけるマトリックスメタロプロテアーゼ2の変動2017

    • Author(s)
      藤本 源、小林 哲、浅山 健太郎、都丸 敦史、高橋 佳紀、藤原 研太郎、大西 真裕、中原 博紀、西濵 康太、安間 太郎、ガバザ コリナ、戸田 雅昭、ガバザ エステバン、田口 修
    • Organizer
      第66回日本アレルギー学会学術大会
    • Data Source
      KAKENHI-PROJECT-17K09611
  • [Presentation] MMP-2過剰発現マウスにおけるタバコ煙抽出液吸入による肺の気腫化の検討2017

    • Author(s)
      大西 真裕、小林 哲、浅山 健太郎、高橋 佳紀、都丸 敦史、藤原 研太郎、中原 博紀、藤本 源、田口 修、戸田 雅昭、ガバザ コリナ、ガバザ エステバン
    • Organizer
      第91回閉塞性肺疾患研究会
    • Data Source
      KAKENHI-PROJECT-17K09611
  • [Presentation] MMP-2過剰発現マウスにおけるタバコ煙抽出液吸入による肺の気腫化の検討2017

    • Author(s)
      大西 真裕、小林 哲、浅山 健太郎、高橋 佳紀、都丸 敦史、藤原 研太郎、中原 博紀、藤本 源、田口 修、戸田 雅昭、ガバザ コリナ、ガバザ エステバン
    • Organizer
      第91回閉塞性肺疾患研究会
    • Data Source
      KAKENHI-PROJECT-15K09170
  • [Presentation] 気道の線維化の先には発癌があるのか?2017

    • Author(s)
      小林 哲、Esteban C. Gabazza、浦田 健太郎、高橋 佳紀、都丸 敦史、藤原 研太郎、大西 真裕、中原 博紀、藤本 源、Corina N. D’Alessandro-Gabazza、戸田 雅昭、田口 修
    • Organizer
      第36回気道分泌研究会
    • Data Source
      KAKENHI-PROJECT-15K09170
  • [Presentation] 気管支喘息患者におけるマトリックスメタロプロテアーゼ2の変動2017

    • Author(s)
      藤本 源、小林 哲、浅山 健太郎、都丸 敦史、高橋 佳紀、藤原 研太郎、大西 真裕、中原 博紀、西濵 康太、安間 太郎、ガバザ コリナ、戸田 雅昭、ガバザ エステバン、田口 修
    • Organizer
      第66回日本アレルギー学会学術大会
    • Data Source
      KAKENHI-PROJECT-15K09170
  • [Presentation] マトリックスメタロプロテアーゼ2遺伝子導入喘息マウスにおける気道病変の解析2017

    • Author(s)
      藤原 研太郎、小林 哲、浅山 健太郎、都丸 敦史、高橋 佳紀、大西 真裕、中原 博紀、藤本 源、西濵 康太、安間 太郎、ガバザ コリナ、戸田 雅昭、ガバザ エステバン、田口 修
    • Organizer
      第66回日本アレルギー学会学術大会
    • Data Source
      KAKENHI-PROJECT-17K09611
  • [Presentation] 気管支喘息におけるmatrix metalloproteinase-2(MMP-2)の変動2017

    • Author(s)
      藤原 研太郎、小林 哲、浅山 健太郎、都丸 敦史、高橋 佳紀、大西 真裕、中原 博紀、藤本 源、ダレッサンドロ ガバザ コリナ、戸田 雅昭、田口 修、ガバザ エステバン
    • Organizer
      第16回Kinki Hokuriku Airway disease Conference
    • Data Source
      KAKENHI-PROJECT-17K09611
  • [Presentation] 膵β細胞にマトリックスメタロプロテイナーゼ2が与える影響についての検討2016

    • Author(s)
      西濵康太,竹下敦郎,Josephine Hinneh,原田栄津子,安間太郎,D’Alessandro Corina Gabazza,戸田雅昭,矢野裕,Esteban Gabazza,竹井謙之
    • Organizer
      第59回日本糖尿病学会年次学術集会
    • Place of Presentation
      国立京都国際会館(京都府・京都市)
    • Year and Date
      2016-05-19
    • Data Source
      KAKENHI-PROJECT-15K09170
  • [Presentation] Targeting Periostin for the Treatment of Pulmunary Fibrosis2015

    • Author(s)
      Gabazza EC, Kobayashi T, D’Alessandro-Gabazza CN, Toda M, Roeen Z, Takahashi Y, Fujiwara K, Hinneh JA, Yasuma T, Taguchi O
    • Organizer
      9th International Symposium on Nanomedicine (ISNM2015)
    • Place of Presentation
      三重大学
    • Year and Date
      2015-12-10
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09170
  • [Presentation] Eosinophils promote epithelial to mesenchymal transition of bronchial epithelial cells2012

    • Author(s)
      K Hosoki, T Fujisawa, M Toda, EC Gabazza
    • Organizer
      American Academy of Allergy, Asthma and Immunology
    • Place of Presentation
      Orland, USA
    • Data Source
      KAKENHI-PROJECT-23591471
  • [Presentation] Eosinophils promote epithelial to mesenchymal transition of bronchial epithelial cells2011

    • Author(s)
      A Yasukawa, K Hosoki, T Fujisawa, M Toda, EC Gabazza
    • Organizer
      第40回日本免疫学会学術集会
    • Place of Presentation
      千葉
    • Data Source
      KAKENHI-PROJECT-23591471
  • 1.  GABAZZA Esteban (00293770)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 45 results
  • 2.  GABAZZA CORINA (10750656)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 35 results
  • 3.  小林 哲 (20437114)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 12 results
  • 4.  竹下 敦郎 (10830490)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 5 results
  • 5.  安間 太郎 (80773887)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 14 results
  • 6.  坂口 志文 (30280770)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  FUJISAWA Takao (20511140)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 8.  HOSOKI Koua (90422831)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 9.  Taguchi Osamu (90197244)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 10.  清水 淳 (60291134)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  Morser John (40571625)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 12.  藤本 源 (90378399)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  ISHINAGA Hajime
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 14.  矢野 裕
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 15.  河岸 洋和
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 16.  都丸 敦史
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 17.  岩佐 元雄
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 18.  野阪 哲哉
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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