Yamaguchi Yoshiyuki 山口佳之

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YAMAGUCHI Yoshiyuki 山口佳之

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Researcher Number	10230377
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2018 – 2023: 川崎医科大学, 医学部, 教授 1997 – 1998: Research Institute for Radiation Biology and Medicine, Hiroshima University, Ass, 原爆放射能医学研究所, 講師 1996: 広島大学, 原爆放射能医学研究所, 助手 1995: 広島大学, 原爆放射能医学研究所・腫瘍外科, 助手 1993 – 1994: 広島大学, 原爆放射能医学研究所, 助手
Review Section/Research Field	Principal Investigator Digestive surgery / Basic Section 50020:Tumor diagnostics and therapeutics-related / General surgery Except Principal Investigator Medium-sized Section 90:Biomedical engineering and related fields / Basic Section 90130:Medical systems-related / Studies on the Super-Aging Society / General surgery
Keywords	Principal Investigator 腫瘍検査学 / 大腸癌 / 腫瘍遺伝学 / 悪性腫瘍 / 逐次療法 / バイオマーカー / メチル化 / MGMT / オキサリプラチン / 逐次治療 … More / 化学療法 / 大腸がん / malignant effusion / T cell receptor (TCR) / CTL / T細胞受容体 (TCR) / 癌性胸腹水 / T細胞受容体(TCR) / 癌特異的リンパ球 / 局所免疫療法 / T細胞受容体 / 腫瘍細胞障害性 T細胞 / CD4モジュレーション / 免疫抑制因子 / 癌免疫不全 … More Except Principal Investigator メチル化 / 生体情報・計測 / 検査・診断システム / 腫瘍検査学 / IL-2 / 脱メチル化 / 癌免疫 / 癌性腹膜炎 / 新規養子免疫細胞療法 / 脱メチル化剤 / 難治性癌性腹水 / 悪性腫瘍 / 予防医学 / 遺伝子検査学 / 臨床検査システム / 固形癌 / エピゲノム / 先制医療 / 超高齢社会研究 / 健康情報 / cytotoxic T lymphocytes / gene transfection / malignant effusion / lymphocyte therapy / エレ-2 / 癌特異的リンパ球 / 遺伝子導入 / 癌性胸腹水 / リンパ球療法 Less

Development of a new strategy to treat cancerous peritonitis
- Principal Investigator
  
  Nagasaka Takeshi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Kawasaki Medical School
Exploration of the Molecular Biological Characteristics of Advanced Colorectal Cancer Suitable for Sequential TherapyPrincipal Investigator
- Principal Investigator
  
  Yamaguchi Yoshiyuki
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kawasaki Medical School
Construction of innovative preemptive medicine for gastrointestinal cancer especially including pancreatic cancer
- Principal Investigator
  
  NAGASAKA TAKESHI
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Studies on the Super-Aging Society
- Research Institution
  Kawasaki Medical School
Preemptive Medicine to Solid Tumors based on Epigenomics
- Principal Investigator
  
  NAGASAKA TAKESHI
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90130:Medical systems-related
- Research Institution
  Kawasaki Medical School
Basic research for cancer-specific immunotherapy using T cell receptorPrincipal Investigator
- Principal Investigator
  
  YAMAGUCHI Oshiyuki
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  HIROSHIMA UNIVERSITY
Development of novel adoptive immunotherapy of malignant effusions using tumor cells genetically engineered to secrete interleukin-2
- Principal Investigator
  
  TOGE Tetsuya
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  HIROSHIMA UNIVERSITY
消化器がん抗原とTリンパ球受容体の解析Principal Investigator
- Principal Investigator
  
  山口佳之
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Digestive surgery
- Research Institution
  Hiroshima University
リンパ球CD4分子のモジュレーションと担癌生体免疫の機能不全Principal Investigator
- Principal Investigator
  
  山口佳之
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Digestive surgery
- Research Institution
  Hiroshima University

All 2023 2022 2021 2020 2019 2018

All Journal Article Presentation

[Journal Article] Neutrophil and lymphocyte ratio before each chemotherapy line predicts clinical outcomes in patients with unresectable gastric cancer.2023
- Author(s)
  Tanioka H, Okawaki M, Yano S, Yoshimitsu T, Tokuda K, Nyuya A, Yamaguchi Y, Nagasaka T.
- Journal Title
  
  Oncol Lett.
  
  Volume: 25 Issue: 3 Pages: 98-98
- DOI
  10.3892/ol.2023.13684
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K16474, KAKENHI-PROJECT-19K07787, KAKENHI-PROJECT-21K07185
[Journal Article] Phase 3 trial of sequential versus combination treatment in colorectal cancer: The C-cubed study2022
- Author(s)
  Ryo Inada, Takeshi Nagasaka, Mototsugu Shimokawa, Hitoshi Ojima, Shingo Noura, Hiroaki Tanioka, Yoshinori Munemoto, Yasuhiro Shimada, Keiichiro Ishibashi, Yoshiaki Shindo, Hideyuki Mishima, Masasumi Okajima, Yoshiyuki Yamaguchi
- Journal Title
  
  European Journal of Cancer
  
  Volume: 169 Pages: 166-178
- DOI
  10.1016/j.ejca.2022.04.009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K19934, KAKENHI-PROJECT-21K07185, KAKENHI-PROJECT-19K07787
[Journal Article] Long‐term (>5-year) survivors among unresectable or metastatic cancer patients treated with zoledronate‐activated killer cells: Seven case reports2022
- Author(s)
  Yamaguchi Yoshiyuki
- Journal Title
  
  Clinical Case Reports
  
  Volume: 10 Issue: 11
- DOI
  10.1002/ccr3.6540
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07787
[Journal Article] Republication: A Prospective Observational Study of Adoptive Immunotherapy for Cancer Using Zoledronate-Activated Killer (ZAK) Cells ? An Analysis for Patients With Incurable Pancreatic Cancer2022
- Author(s)
  YAMAGUCHI YOSHIYUKI、KATATA YOUSUKE、OKAWAKI MAKOTO、SAWAKI AKIRA、YAMAMURA MASAHIRO
- Journal Title
  
  Anticancer Research
  
  Volume: 42 Issue: 2 Pages: 1181-1187
- DOI
  10.21873/anticanres.15584
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07787
[Journal Article] Clinical and epigenetic features of colorectal cancer patients with somatic POLE proofreading mutations.2021
- Author(s)
  Kawai T, Nyuya A, Mori Y, Tanaka T, Tanioka H, Yasui K, Toshima T, Taniguchi F, Shigeyasu K, Umeda Y, Fujiwara T, Okawaki M, Yamaguchi Y, Goel A, Nagasaka T.
- Journal Title
  
  Clin Epigenetics.
  
  Volume: 13 (1) Issue: 1 Pages: 117-117
- DOI
  10.1186/s13148-021-01104-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09217, KAKENHI-PROJECT-19K07787, KAKENHI-PROJECT-20K09110, KAKENHI-PROJECT-21K07185, KAKENHI-PROJECT-21K19934
[Journal Article] Concordance of acquired mutations between metastatic lesions and liquid biopsy in metastatic colorectal cancer.2021
- Author(s)
  Taniguchi F, Nyuya A, Toshima T, Yasui K, Mori Y, Okawaki M, Kishimoto H, Umeda Y, Fujiwara T, Tanioka H, Yamaguchi Y, Goel A, Nagasaka T.
- Journal Title
  
  Future Sci OA.
  
  Volume: 7 (10) Issue: 10
- DOI
  10.2144/fsoa-2021-0059
- NAID
  120007170517
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09217, KAKENHI-PROJECT-19K07787, KAKENHI-PROJECT-20K09110, KAKENHI-PROJECT-21K07185, KAKENHI-PROJECT-21K19934
[Journal Article] Adoptive immunotherapy for gastric cancer using zoledronate-activated killer cells: A prospective observational study2020
- Author(s)
  Yamaguchi, Y. Katata, Y. Sano, F. Tanioka, H. Okawaki, M. Yamamura, M. Nagasaka, T.
- Journal Title
  
  Mol Clin Oncol
  
  Volume: 13 Issue: 5 Pages: 55-55
- DOI
  10.3892/mco.2020.2125
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07787
[Journal Article] Upregulation of microRNA?31 is associated with poor prognosis in patients with advanced colorectal cancer2020
- Author(s)
  Kubota Nobuhito、Taniguchi Fumitaka、Nyuya Akihiro、Umeda Yuzo、Mori Yoshiko、Fujiwara Toshiyoshi、Tanioka Hiroaki、Tsuruta Atsushi、Yamaguchi Yoshiyuki、Nagasaka Takeshi
- Journal Title
  
  Oncology Letters
  
  Volume: 19（４） Pages: 2685-2694
- DOI
  10.3892/ol.2020.11365
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07787, KAKENHI-PROJECT-19K09217, KAKENHI-PROJECT-18K18464, KAKENHI-PROJECT-18H03554, KAKENHI-PROJECT-17K10634, KAKENHI-PROJECT-20K09110
[Journal Article] The relationship between peripheral neuropathy and efficacy in second-line chemotherapy for unresectable advanced gastric cancer: a prospective observational multicenter study protocol (IVY)2019
- Author(s)
  Tanioka Hiroaki、Nagasaka Takeshi、Uno Futoshi、Inoue Masafumi、Okita Hiroyuki、Katata Yosuke、Kanzaki Hiromitsu、Kuramochi Hidekazu、Satake Hironaga、Shindo Yoshiaki、Doi Akira、Nasu Jyunichiro、Yamashita Haruhiro、Yamaguchi Yoshiyuki
- Journal Title
  
  BMC Cancer
  
  Volume: 19 Issue: 1 Pages: 941-941
- DOI
  10.1186/s12885-019-6163-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H03554
[Journal Article] Clinical outcomes of women with ovarian metastases of colorectal cancer treated with oophorectomy with respect to their somatic mutation profiles.2018
- Author(s)
  Mori Y, Nyuya A, Yasui K, Toshima T, Kawai T, Taniguchi F, Kimura K, Inada R, Nishizaki M, Haraga J, Nakamura K, Umeda Y, Kishimoto H, Fujiwara T, Katata Y, Yamaguchi Y, Nagasaka T.
- Journal Title
  
  Oncotarget
  
  Volume: 27;9(23) Issue: 23 Pages: 16477-16488
- DOI
  10.18632/oncotarget.24735
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10573, KAKENHI-PROJECT-16K11141, KAKENHI-PROJECT-17K10634, KAKENHI-PROJECT-18K18464, KAKENHI-PROJECT-18H03554, KAKENHI-PROJECT-15H03034
[Journal Article] [Analysis of Fecal Cancer-Specific DNA to Detect Colorectal Neoplasia]2018
- Author(s)
  Nagasaka, T. Yamaguchi, Y.
- Journal Title
  
  Gan To Kagaku Ryoho
  
  Volume: 45 Pages: 906-910
- Data Source
  KAKENHI-PROJECT-18K18464
[Journal Article] Heterogeneity of Epigenetic and Epithelial Mesenchymal Transition Marks in Hepatocellular Carcinoma with Keratin 19 Proficiency2018
- Author(s)
  Yokomichi Naosuke、Nishida Naoshi、Umeda Yuzo、Taniguchi Fumitaka、Yasui Kazuya、Toshima Toshiaki、Mori Yoshiko、Nyuya Akihiro、Tanaka Takehiro、Yamada Takeshi、Yagi Takahito、Fujiwara Toshiyoshi、Yamaguchi Yoshiyuki、Goel Ajay、Kudo Masatoshi、Nagasaka Takeshi
- Journal Title
  
  Liver Cancer
  
  Volume: none Issue: 4 Pages: 1-16
- DOI
  10.1159/000490806
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K18464, KAKENHI-PROJECT-18H03554, KAKENHI-PROJECT-18K07922, KAKENHI-PROJECT-19K09217, KAKENHI-PROJECT-17K10634
[Journal Article] [Analysis of Fecal Cancer-Specific DNA to Detect Colorectal Neoplasia]2018
- Author(s)
  Nagasaka, T. and Y. Yamaguchi
- Journal Title
  
  Gan To Kagaku Ryoho
  
  Volume: 45 Pages: 906-910
- Data Source
  KAKENHI-PROJECT-18H03554
[Presentation] Wnt signaling cascade における低メチル化を特徴とする Genomically stable 胃癌2022
- Author(s)
  谷岡洋亮, 安井和也, 母里淑子, 田中健大, 木村圭介, 入谷光洋, 岡脇誠, 矢野修也, 山口佳之, 永坂岳司
- Organizer
  第60回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07787
[Presentation] せん妄発症予測バイオマーカーの探索2022
- Author(s)
  岡脇誠, 永坂岳司, 谷岡洋亮, 矢野修也, 山口佳之
- Organizer
  第60回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07787
[Presentation] 胃癌ニボルマブ投与による末梢血 PD1CD8 陽性 T リンパ球変化は効果予測となりうる2021
- Author(s)
  谷岡洋亮, 永坂岳司, 堅田洋佑, 岡脇誠, 山村真宏, 山口佳之
- Organizer
  第 59 回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07787
[Presentation] 胃癌ニボルマブ投与による末梢血 PD1CD8 陽性 T リンパ球変化は効果予測となりうる2021
- Author(s)
  谷岡洋亮, 永坂岳司, 堅田洋佑, 岡脇誠, 山村真宏, 山口佳之
- Organizer
  第 59 回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-21K19934
[Presentation] 進行性消化管間質腫瘍に対するレゴラフェニブ療法により誘発された多形紅斑の2例2020
- Author(s)
  岡脇誠, 永坂岳司, 佐野史典, 谷岡洋亮, 堅田洋祐, 山村真弘, 山口佳之
- Organizer
  第58回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-18H03554
[Presentation] 切除不能胃癌患者の各治療開始前好中球リンパ球比と抗腫瘍効果の検討：3次治療ニボルマブの抗腫瘍効果を中心に2020
- Author(s)
  谷岡洋亮, 永坂岳司, 堅田洋祐, 佐野史典, 岡脇誠, 山村真弘, 山口佳之
- Organizer
  第33回日本バイオセラピィ学会学術集会総会
- Data Source
  KAKENHI-PROJECT-18K18464
[Presentation] 急性骨髄性白血病・骨髄異形成症候群末期患者の倦怠感に対するステロイドの有用性2020
- Author(s)
  佐野史典, 岡脇誠, 永坂岳司, 山口佳之
- Organizer
  第25回日本緩和医療学会学術大会
- Data Source
  KAKENHI-PROJECT-18H03554
[Presentation] 進行性消化管間質腫瘍に対するレゴラフェニブ療法により誘発された多形紅斑の2例2020
- Author(s)
  岡脇誠, 永坂岳司, 佐野史典, 谷岡洋亮, 堅田洋祐, 山村真弘, 山口佳之
- Organizer
  第58回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-18K18464
[Presentation] Cell-free and concentrated ascites reinfusion therapy (CART)におけるNeutrophil to Lymphocyte Ratioと予後の関係2020
- Author(s)
  岡脇誠, 永坂岳司, 佐野史典, 谷岡洋亮, 堅田洋祐, 山村真弘, 山口佳之
- Organizer
  第33回日本バイオセラピィ学会学術集会総会
- Data Source
  KAKENHI-PROJECT-18K18464
[Presentation] Precision　Palliative　Active　Care　Programにより最終末期のwell-beingを達成し得た1症例2020
- Author(s)
  高橋誉文, 岡脇誠, 永坂岳司, 佐野史典, 井上明子, 金原唯奈, 出口美穂, 山口佳之
- Organizer
  第25回日本緩和医療学会学術大会
- Data Source
  KAKENHI-PROJECT-18K18464
[Presentation] Precision　Palliative　Active　Care　Programにより最終末期のwell-beingを達成し得た1症例2020
- Author(s)
  高橋誉文, 岡脇誠, 永坂岳司, 佐野史典, 井上明子, 金原唯奈, 出口美穂, 山口佳之
- Organizer
  第25回日本緩和医療学会学術大会
- Data Source
  KAKENHI-PROJECT-18H03554
[Presentation] 希少がんに対する治療から緩和への流れを再考する(一症例から何が学べるか?)2020
- Author(s)
  岡脇誠, 永坂岳司, 佐野史典, 山口佳之
- Organizer
  第25回日本緩和医療学会学術大会
- Data Source
  KAKENHI-PROJECT-18H03554
[Presentation] 抗VEGF抗体RAMUCIRUMABによる肝転移巣の肝類洞血小板凝集2020
- Author(s)
  永坂岳司, 田中健大, 母里淑子, 谷岡洋亮, 堅田洋佑, 岡脇誠, 佐野史典, 山村真弘, 山口佳之
- Organizer
  第33回日本バイオセラピィ学会学術集会総会
- Data Source
  KAKENHI-PROJECT-18H03554
[Presentation] 希少がんに対する治療から緩和への流れを再考する(一症例から何が学べるか?)2020
- Author(s)
  岡脇誠, 永坂岳司, 佐野史典, 山口佳之
- Organizer
  第25回日本緩和医療学会学術大会
- Data Source
  KAKENHI-PROJECT-18K18464
[Presentation] 切除不能胃癌患者の各治療開始前好中球リンパ球比と抗腫瘍効果の検討：3次治療ニボルマブの抗腫瘍効果を中心に2020
- Author(s)
  谷岡洋亮, 永坂岳司, 堅田洋祐, 佐野史典, 岡脇誠, 山村真弘, 山口佳之
- Organizer
  第33回日本バイオセラピィ学会学術集会総会
- Data Source
  KAKENHI-PROJECT-18H03554
[Presentation] 大腸癌肝転移における抗VEGF抗体による肝類洞血小板凝集効果と肝切除2020
- Author(s)
  永坂岳司, 田中健大, 母里淑子, 谷岡洋亮, 堅田洋佑, 佐野史典, 岡脇誠, 山村真弘, 吉田一博, 重安邦俊, 楳田祐三, 山口佳之
- Organizer
  第58回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-18K18464
[Presentation] 低好中球リンパ球比は胃癌化学療法の良好な抗腫瘍効果の予測因子となりうる2020
- Author(s)
  谷岡洋亮, 永坂岳司, 堅田洋祐, 佐野史典, 岡脇誠, 山村真弘, 山口佳之
- Organizer
  第58回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-18K18464
[Presentation] 急性骨髄性白血病・骨髄異形成症候群末期患者の倦怠感に対するステロイドの有用性2020
- Author(s)
  佐野史典, 岡脇誠, 永坂岳司, 山口佳之
- Organizer
  第25回日本緩和医療学会学術大会
- Data Source
  KAKENHI-PROJECT-18K18464
[Presentation] 大腸癌肝転移における抗VEGF抗体による肝類洞血小板凝集効果と肝切除2020
- Author(s)
  永坂岳司, 田中健大, 母里淑子, 谷岡洋亮, 堅田洋佑, 佐野史典, 岡脇誠, 山村真弘, 吉田一博, 重安邦俊, 楳田祐三, 山口佳之
- Organizer
  第58回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-18H03554
[Presentation] 抗VEGF抗体RAMUCIRUMABによる肝転移巣の肝類洞血小板凝集2020
- Author(s)
  永坂岳司, 田中健大, 母里淑子, 谷岡洋亮, 堅田洋佑, 岡脇誠, 佐野史典, 山村真弘, 山口佳之
- Organizer
  第33回日本バイオセラピィ学会学術集会総会
- Data Source
  KAKENHI-PROJECT-18K18464
[Presentation] 低好中球リンパ球比は胃癌化学療法の良好な抗腫瘍効果の予測因子となりうる2020
- Author(s)
  谷岡洋亮, 永坂岳司, 堅田洋祐, 佐野史典, 岡脇誠, 山村真弘, 山口佳之
- Organizer
  第58回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-18H03554
[Presentation] Cell-free and concentrated ascites reinfusion therapy (CART)におけるNeutrophil to Lymphocyte Ratioと予後の関係2020
- Author(s)
  岡脇誠, 永坂岳司, 佐野史典, 谷岡洋亮, 堅田洋祐, 山村真弘, 山口佳之
- Organizer
  第33回日本バイオセラピィ学会学術集会総会
- Data Source
  KAKENHI-PROJECT-18H03554
[Presentation] Genetic 変異情報と Epigenetic 変異情報の融合による新機軸大腸癌 Precision Medicine2019
- Author(s)
  永坂岳司, 入谷光洋, 鶴田淳, 渡邊裕策, 峯田修明, 母里淑子, 重安邦俊, 楳田祐三, 岸本浩行, 上野富雄, 山口佳之
- Organizer
  第74回日本大腸肛門病学会学術集会
- Data Source
  KAKENHI-PROJECT-18K18464
[Presentation] 抗EGFR抗体によるRAS野生型大腸癌獲得変異に対する検討2019
- Author(s)
  永坂岳司, 入谷光洋, 谷口文崇, 戸嶋俊明, 安井和也, 母里淑子, 楳田祐三, 岸本浩行, 河合毅, 山口佳之
- Organizer
  第57回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07787
[Presentation] Genetic Stable胃癌における病理分子生物学的特徴の検討2019
- Author(s)
  谷岡洋亮, 木村圭佑, 入谷光洋, 堅田洋佑, 山口佳之, 永坂岳司
- Organizer
  第57回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-18H03554
[Presentation] Relationship between peripheral neuropathy and effectiveness in second-line chemotherapy for unresectable advanced gastric cancer: a prospective, observational, multicenter study protocol2019
- Author(s)
  H Tanioka, T Nagasaka, F Uno, M Inoue, H Okita, Y Katata, H Kanzaki, H Kuramochi, H Satake, Y Shindo, A Doi, J Nasu, H Yamashita, Y Yamaguchi
- Organizer
  World Congress on Gastrointestinal Cancer 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03554
[Presentation] Poor prognosis of hypermutant colorectal cancer with KRAS mutations: A retrospective analysis of 1,052 Japanese colorectal cancer patients without treatment of immuno-checkpoint inhibitors2019
- Author(s)
  T Nagasaka, H Tanioka, A Nyuya, Y Katata, M Okawaki, M Yamamura, T Kawai, K Yasui, T Toshima, Y Mori, Y Umeda, A Tsuruta, T Ueno, Y Yamaguchi
- Organizer
  World Congress on Gastrointestinal Cancer 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K18464
[Presentation] Randomized phase III study of sequential treatment with capecitabine or 5-fluorouracil (FP) plus bevacizumab (BEV) followed by the addition with oxaliplatin (OX) versus initial combination with OX+FP+ BEV in the first-line chemotherapy for metastatic colorectal cancer: The C-cubed study2019
- Author(s)
  T. Nagasaka, R. Inada, H. Ojima, S. Noura, H. Tanioka, Y. Munemoto, Y. Shimada, K. Ishibashi, Y. Shindo, Y. Kagawa, A. Tomibayashi, K. Okamoto, A. Tsuji, Y. Tsuji, S. Yamaguchi, A. SAWAKI, H. Mishima, M. Shimokawa, M. Okajima, Y. Yamaguchi
- Organizer
  ESMO Congress 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07787
[Presentation] KRAS 変異 Hypermutant 大腸癌の特長：A Retrospective Analysis of 1,052 Japanese Colorectal Cancer Patients without Treatment of Immuno-checkpoint Inhibitors.2019
- Author(s)
  永坂岳司, 谷岡洋亮, 堅田洋佑, 岡脇誠, 山村真弘, 山口佳之
- Organizer
  第25回日本家族性腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-18H03554
[Presentation] Randomized phase III study of sequential treatment with capecitabine or 5-fluorouracil (FP) plus bevacizumab (BEV) followed by the addition with oxaliplatin (OX) versus initial combination with OX+FP+ BEV in the first-line chemotherapy for metastatic colorectal cancer: The C-cubed study2019
- Author(s)
  T. Nagasaka, R. Inada, H. Ojima, S. Noura, H. Tanioka, Y. Munemoto, Y. Shimada, K. Ishibashi, Y. Shindo, Y. Kagawa, A. Tomibayashi, K. Okamoto, A. Tsuji, Y. Tsuji, S. Yamaguchi, A. SAWAKI, H. Mishima, M. Shimokawa, M. Okajima, Y. Yamaguchi
- Organizer
  ESMO Congress 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03554
[Presentation] Poor prognosis of hypermutant colorectal cancer with KRAS mutations: A retrospective analysis of 1,052 Japanese colorectal cancer patients without treatment of immuno-checkpoint inhibitors2019
- Author(s)
  T Nagasaka, H Tanioka, A Nyuya, Y Katata, M Okawaki, M Yamamura, T Kawai, K Yasui, T Toshima, Y Mori, Y Umeda, A Tsuruta, T Ueno, Y Yamaguchi
- Organizer
  World Congress on Gastrointestinal Cancer 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03554
[Presentation] 抗EGFR抗体によるRAS野生型大腸癌獲得変異に対する検討2019
- Author(s)
  永坂岳司, 入谷光洋, 谷口文崇, 戸嶋俊明, 安井和也, 母里淑子, 楳田祐三, 岸本浩行, 河合毅, 山口佳之
- Organizer
  第57回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-18H03554
[Presentation] がん免疫療法とはー免疫チェックポイント阻害剤によるがん治療の変革―2019
- Author(s)
  山口佳之
- Organizer
  第60回日本人間ドック学会学術大会
- Data Source
  KAKENHI-PROJECT-19K07787
[Presentation] Genetic Stable胃癌における病理分子生物学的特徴の検討2019
- Author(s)
  谷岡洋亮, 木村圭佑, 入谷光洋, 堅田洋佑, 山口佳之, 永坂岳司
- Organizer
  第57回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-18K18464
[Presentation] 血中遊離メチル化 DNA をバイオマーカーに用いた Liquid Biopsy による大腸癌診断の可能性2019
- Author(s)
  永坂岳司, 入谷光洋, 戸嶋俊明, 安井和也, 稲田涼, 母里淑子, 重安邦俊, 楳田祐三, 岸本浩行, 山口佳之
- Organizer
  第74回日本大腸肛門病学会学術集会
- Data Source
  KAKENHI-PROJECT-18H03554
[Presentation] Genetic 変異情報と Epigenetic 変異情報の融合による新機軸大腸癌 Precision Medicine2019
- Author(s)
  永坂岳司, 入谷光洋, 鶴田淳, 渡邊裕策, 峯田修明, 母里淑子, 重安邦俊, 楳田祐三, 岸本浩行, 上野富雄, 山口佳之
- Organizer
  第74回日本大腸肛門病学会学術集会
- Data Source
  KAKENHI-PROJECT-18H03554
[Presentation] 血中遊離メチル化 DNA をバイオマーカーに用いた Liquid Biopsy による大腸癌診断の可能性2019
- Author(s)
  永坂岳司, 入谷光洋, 戸嶋俊明, 安井和也, 稲田涼, 母里淑子, 重安邦俊, 楳田祐三, 岸本浩行, 山口佳之
- Organizer
  第74回日本大腸肛門病学会学術集会
- Data Source
  KAKENHI-PROJECT-18K18464
[Presentation] 抗EGFR抗体によるRAS野生型大腸癌獲得変異に対する検討2019
- Author(s)
  永坂岳司, 入谷光洋, 谷口文崇, 戸嶋俊明, 安井和也, 母里淑子, 楳田祐三, 岸本浩行, 河合毅, 山口佳之
- Organizer
  第57回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-18K18464
[Presentation] Genetic 変異情報と Epigenetic 変異情報の融合による新機軸大腸癌 Precision Medicine2019
- Author(s)
  永坂岳司, 入谷光洋, 鶴田淳, 渡邊裕策, 峯田修明, 母里淑子, 重安邦俊, 楳田祐三, 岸本浩行, 上野富雄, 山口佳之
- Organizer
  第74回日本大腸肛門病学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07787
[Presentation] 循環血液中Ago2複合体miRNA測定による大腸癌スクリーニングと化学療法効果予測2018
- Author(s)
  永坂岳司、藤智和、楳田祐三、入谷光洋、藤原俊義、堅田洋祐、谷岡洋亮、岡脇誠、山村真弘、山口佳之
- Organizer
  the 73rd General Meeting of the Japanese Society of Gastroenterological Surgery
- Data Source
  KAKENHI-PROJECT-18H03554
[Presentation] Primary Tumor Location と Genetic/Epigenetic変異分布不均衡に対する検討2018
- Author(s)
  永坂岳司、堅田洋祐、岡脇誠、山村真弘、母里淑子、安井和也、戸嶋俊明、岸本浩行、藤原俊儀、山口佳之
- Organizer
  第88回大腸癌研究会
- Data Source
  KAKENHI-PROJECT-18H03554
[Presentation] Lynch 症候群を含むHypermutant大腸癌における臨床病理学的特徴2018
- Author(s)
  永坂岳司、母里淑、鶴田淳、谷岡洋亮、堅田洋佑、重安邦俊、岸本浩行、矢野修也、戸嶋俊明、岡脇誠、山村真弘、谷口文崇、楳田祐三、河合毅、河合知則、上野富雄、山口佳之
- Organizer
  第73回日本大腸肛門病学会学術集会
- Data Source
  KAKENHI-PROJECT-18H03554
[Presentation] Lynch 症候群を含むHypermutant 大腸癌における臨床病理学的特徴2018
- Author(s)
  永坂岳司、母里淑、鶴田淳、谷岡洋亮、堅田洋佑、重安邦俊、岸本浩行、矢野修也、戸嶋俊明、岡脇誠、山村真弘、谷口文崇、楳田祐三、河合毅、河合知則、上野富雄、山口佳之
- Organizer
  第73回日本大腸肛門病学会学術集会
- Data Source
  KAKENHI-PROJECT-18K18464
[Presentation] POLE変異大腸癌の臨床病理学的特徴2018
- Author(s)
  永坂岳司、母里淑子、入谷光洋、原賀順子、重安邦俊、山村真弘、堅田洋佑、谷岡洋亮、升野光雄、山口佳之
- Organizer
  第63回日本人類遺伝学会
- Data Source
  KAKENHI-PROJECT-18H03554
[Presentation] POLE変異大腸癌の臨床病理学的特徴2018
- Author(s)
  永坂岳司、母里淑子、入谷光洋、原賀順子、重安邦俊、山村真弘、堅田洋佑、谷岡洋亮、升野光雄、山口佳之
- Organizer
  第63回日本人類遺伝学会
- Data Source
  KAKENHI-PROJECT-18K18464
[Presentation] 循環血液中Ago2-miRNA検出による化学療法効果予測の検討2018
- Author(s)
  永坂岳司、藤智和、堅田洋祐、谷岡洋亮、岡脇誠、山村真弘、楳田祐三、藤原俊義、入谷光洋、山口佳之
- Organizer
  第40回日本癌局所療法研究会
- Data Source
  KAKENHI-PROJECT-18H03554
[Presentation] Distinct Clinico-pathological Features of Hypermutant Colorectal Cancers with POLE Pathogenic Mutations, Lynch Syndrome, or Sporadic MSI over 1,000 colorectal cancer patients’ cohort in Japan.2018
- Author(s)
  Takeshi Nagasaka, Akihiro Nyuya, Fumitaka Taniguchi, Hiroaki Tanioka, Yosuke Katata, Yoshiko Mori, Takashi Kawai, Makoto Okawaki, Masahiro Yamamura, Yuzo Umeda, Atsushi Turuta, Tomio Ueno, Yoshiyuki Yamaguchi
- Organizer
  ESMO 2018
- Data Source
  KAKENHI-PROJECT-18K18464
[Presentation] Distinct Clinico-pathological Features of Hypermutant Colorectal Cancers with POLE Pathogenic Mutations, Lynch Syndrome, or Sporadic MSI over 1,000 colorectal cancer patients’ cohort in Japan.2018
- Author(s)
  Takeshi Nagasaka, Akihiro Nyuya, Fumitaka Taniguchi, Hiroaki Tanioka, Yosuke Katata, Yoshiko Mori, Takashi Kawai, Makoto Okawaki, Masahiro Yamamura, Yuzo Umeda, Atsushi Turuta, Tomio Ueno, Yoshiyuki Yamaguchi
- Organizer
  ESMO2018
- Data Source
  KAKENHI-PROJECT-18H03554
[Presentation] ＰＯＬＥ体細胞変異大腸癌の臨床病理学的特徴2018
- Author(s)
  堅田洋佑、永坂岳司1、入谷光洋、田中健大、河合毅、母里淑子、岡脇誠、山村真弘、谷岡洋亮、山口佳之
- Organizer
  第29回消化器癌発生学会学術集会
- Data Source
  KAKENHI-PROJECT-18H03554
[Presentation] ＰＯＬＥ体細胞変異大腸癌の臨床病理学的特徴2018
- Author(s)
  堅田洋佑、永坂岳司1、入谷光洋、田中健大、河合毅、母里淑子、岡脇誠、山村真弘、谷岡洋亮、山口佳之
- Organizer
  第29回消化器癌発生学会学術集会
- Data Source
  KAKENHI-PROJECT-18K18464

1. NAGASAKA TAKESHI (30452569)

# of Collaborated Projects: 4 results

# of Collaborated Products: 59 results
2. 堅田洋佑 (20716881)

# of Collaborated Projects: 3 results

# of Collaborated Products: 25 results
3. 楳田祐三 (10573735)

# of Collaborated Projects: 2 results

# of Collaborated Products: 20 results
4. 母里淑子 (70708081)

# of Collaborated Projects: 2 results

# of Collaborated Products: 23 results
5. 谷岡洋亮 (40775491)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
6. MIYAHARA Eiji

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 野間浩介

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. TOGE Tetsuya (40034657)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 西田直生志 (60281755)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 堀田勝幸 (70379816)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 岡脇誠 (40509254)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 矢野修也 (50794624)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. 佐藤幸雄

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 柳原五吉

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 川見弘之

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. FUJI Tomokazu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. YASUI Kazuya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 藤原俊義

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
19. 重安邦俊

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yamaguchi Yoshiyuki 山口 佳之

YAMAGUCHI Yoshiyuki 山口 佳之

Research Projects

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Co-Researchers

Development of a new strategy to treat cancerous peritonitis

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Exploration of the Molecular Biological Characteristics of Advanced Colorectal Cancer Suitable for Sequential TherapyPrincipal Investigator

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Construction of innovative preemptive medicine for gastrointestinal cancer especially including pancreatic cancer

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Preemptive Medicine to Solid Tumors based on Epigenomics

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Basic research for cancer-specific immunotherapy using T cell receptorPrincipal Investigator

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Development of novel adoptive immunotherapy of malignant effusions using tumor cells genetically engineered to secrete interleukin-2

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消化器がん抗原とTリンパ球受容体の解析Principal Investigator

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リンパ球CD4分子のモジュレーションと担癌生体免疫の機能不全Principal Investigator

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[Journal Article] Neutrophil and lymphocyte ratio before each chemotherapy line predicts clinical outcomes in patients with unresectable gastric cancer.2023

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[Journal Article] Phase 3 trial of sequential versus combination treatment in colorectal cancer: The C-cubed study2022

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[Journal Article] Long‐term (>5-year) survivors among unresectable or metastatic cancer patients treated with zoledronate‐activated killer cells: Seven case reports2022

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[Journal Article] Republication: A Prospective Observational Study of Adoptive Immunotherapy for Cancer Using Zoledronate-Activated Killer (ZAK) Cells ? An Analysis for Patients With Incurable Pancreatic Cancer2022

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[Journal Article] Clinical and epigenetic features of colorectal cancer patients with somatic POLE proofreading mutations.2021

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[Journal Article] Concordance of acquired mutations between metastatic lesions and liquid biopsy in metastatic colorectal cancer.2021

Author(s)

Yamaguchi Yoshiyuki 山口佳之

YAMAGUCHI Yoshiyuki 山口佳之