HIRUMA Hiromi 比留間弘美

Researcher Number	10238397
Other IDs
External Links
Affiliation (Current)	2022: 北里大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2008 – 2010: Kitasato University, 医学部, 准教授 2003 – 2006: 北里大学, 医学部, 助教授 1999 – 2001: 北里大学, 医学部, 助教授 1997 – 1998: 北里大学, 医学部, 講師 1991 – 1996: Yokohama City University School of Medicine, Instructor, 医学部, 助手
Review Section/Research Field	Principal Investigator Obstetrics and gynecology / Neuroscience in general / Environmental physiology (including Physical medicine and Nutritional physiology) / Psychiatric science / Neurology / Nerve anatomy/Neuropathology / Neurochemistry/Neuropharmacology Except Principal Investigator 環境生理学(含体力医学･栄養生理学)
Keywords	Principal Investigator 軸索輸送 / アルツハイマー病 / アクチン / axonal transport / Alzheimer's disease / 細胞骨格 / 黄体形成ホルモン放出ホルモンニューロン / 黄体形成ホルモン放出ホルモン / 多ニューロン発火活動 / パルス状黄体形成ホルモン分泌 … More / 正中隆起部 / 内側視索前野 / LHRH神経回路 / LHRHパルス発生器 / 脳切片 / パッチクランプ / エストロジェン / 視床下部ニューロン / ラット / 膜作用 / イオンチャネル / アンギオテンシンII / アミロイドβ蛋自 / 軸索障害 / アミロイドベータ蛋白 / アンギオテンシン受容体 / 培養海馬ニューロン / アミロイド蛋白β / GnRHニューロン / 神経回路 / 多電極皿記録法 / 周期性活動 / 同期活動 / 視床下部 / GnRH neurons / Neuronal network / Multi-channel recordings / Synchronized activity / Hypothalamus / アミロイド蛋白 / 海馬 / タウ蛋白リン酸化 / ニューロフィラメント / amyloid protein / hippocampus / tau phosphorylation / ベータアミロイド / 軸策輸送 / β-Amyloid / Axonal transport / Cytoskeleton / Actin filaments / ベータアミロイド蛋白 / beta-amyloid protein / actin / cytoskeleton … More Except Principal Investigator 多ニューロン発射活動 / LHRHニューロン / 視床下部正中隆起 / エストロゲン / 正フィードバック / ラット / Multiunit activity / LHRH neurons / Positive feedback / GABA / LHサージ / オピオイドニューロン / 多ニュ-ロン発射活動 / LHRHニュ-ロン / LH分泌 / フィ-ドバック / オピオイドニュ-ロン / GABAニュ-ロン / 内側視索前野 / プロゲステロン / Median eminence of the hypothalamus / LH surge / Estrogen / Opioid peptides / LH / 基礎分泌 / 相動性分泌 / エストロジェン / オピオイド / 負フィードバック / Median eminence / Phasic LH secretion / Tonic LH secretion / Negative feedback / Opioid Less

Enhancement effects of angiotensin II on amyloid 3-induced axonal impairmentPrincipal Investigator
- Principal Investigator
  
  HIRUMA Hiromi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Kitasato University
Insertion of beta-amyloid protein into the cell membrane followed by actin aggregation and impairment of axonal transportPrincipal Investigator
- Principal Investigator
  
  HIRUMA Hiromi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Kitasato University
β-Amyloid-induced changes in cytoskeletons and impairment of axonal transportPrincipal Investigator
- Principal Investigator
  
  HIRUMA Hiromi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Kitasato University
Inhibition of axonal transport of hippocampal neurons by amyloid proteins: relation to Alzheimer's diseasePrincipal Investigator
- Principal Investigator
  
  HIRUMA Hiromi
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kitasato University
Mechanisms for periodic and synchronized activity of GnRH neuronsPrincipal Investigator
- Principal Investigator
  
  HIRUMA Hiromi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  KITASATO UNIVERSITY
ラット視床下部単一ニューロンにおけるエストロジェン応答の可変性Principal Investigator
- Principal Investigator
  
  比留間弘美
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Yokohama City University
LHRH神経回路がLHRHパルス発生器である可能性:脳切片記録法による検討Principal Investigator
- Principal Investigator
  
  比留間弘美
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Environmental physiology (including Physical medicine and Nutritional physiology)
- Research Institution
  Yokohama City University
黄体形成ホルモン放出ホルモン(LHRH)ニューロン同時発火の機序:LHRHの役割Principal Investigator
- Principal Investigator
  
  比留間弘美
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Neuroscience in general
- Research Institution
  Yokohama City University
Electrophysiological demonstration of the functional bimorphism of LHRH neurons in rats
- Principal Investigator
  
  TANAKA Fukuko
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  環境生理学(含体力医学･栄養生理学)
- Research Institution
  Yokohama City University
Electrophysiological identification of LHRH neurons that are involved in the LH surge induced by positive feedback action of estrogen.
- Principal Investigator
  
  TANAKA Fukuko
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  環境生理学(含体力医学･栄養生理学)
- Research Institution
  Yokohama City University

All 2011 2010 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation

[Journal Article] Characteristics of weak base-induced vacuoles formed around individual acidic organelle.2011
- Author(s)
  Hiruma H, Kawakami T
- Journal Title
  
  Folia Histochem Cytobiol (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591418
[Journal Article] Rapid inhibitory effect of progesterone on axonal transport in isolated and cultured mouse dorsal root ganglion neurons.2010
- Author(s)
  Katakura T, Hiruma H, Isonaka R, Kawakami T
- Journal Title
  
  The Kitasato Medical Journal 40
  
  Pages: 12-19
- NAID
  40017023141
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591418
[Journal Article] Effects of 4-aminopyridine on organelle movement in cultured mouse dorsal root ganglion neurites2010
- Author(s)
  Hiruma H, Kawakami T
- Journal Title
  
  J Mol Neurosci 40
  
  Pages: 295-302
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591418
[Journal Article] Rapid inhibitory effect of progesterone on axonal transport in isolated and cultured mouse dorsal root ganglion neurons2010
- Author(s)
  Katakura T, Hiruma H, Isonaka R, Kawakami T
- Journal Title
  
  Kitasato Med J 40
  
  Pages: 12-19
- NAID
  40017023141
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591418
[Journal Article] Effects of 4-aminopyridine on organelle movement in cultured mouse dorsal root ganglion neurites.2010
- Author(s)
  Hiruma H, Kawakami T
- Journal Title
  
  J Mol Neurosci 40(3)
  
  Pages: 295-302
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591418
[Journal Article] Inhibition of Axonal Transport Caused by tert-Butyl Hydroperoxide in Cultured Mouse Dorsal Root Ganglion Neurons.2010
- Author(s)
  Isonaka R, Hiruma H, Kawakami T
- Journal Title
  
  J Mol Neurosci (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591418
[Journal Article] Spinal procaine is less neurotoxic than mepivacaine, prilocaine and bupivacaine in rats.2009
- Author(s)
  Takenami T, Yagishita S, Nara Y, Tsai YH, Hiruma H, Kawakami T, Hoka S
- Journal Title
  
  Reg Anesth Pain Med 34(3)
  
  Pages: 189-195
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591418
[Journal Article] Spinal procaine is less neurotoxic than mepivacaine, prilocaine and bupivacaine in rats2009
- Author(s)
  Takenami T, Yagishita S, Nara Y, Tsai YH, Hiruma H, Kawakami T, Hoka S
- Journal Title
  
  Reg Anesth Pain Med 34
  
  Pages: 189-195
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591418
[Journal Article] Effects of clonidine on lidocaine-induced inhibition of axonal transport in cultured mouse dorsal root gangklion neuornes2008
- Author(s)
  Hiruma H, Shimizu K, Takenami T, Sugie H, Kawakami T
- Journal Title
  
  British Journal of Anaesthesia 101
  
  Pages: 659-665
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591418
[Journal Article] Effects of clonidine on lidocaine-induced inhibition of axonal transport in cultured mouse dorsal root ganglion neurones.2008
- Author(s)
  Hiruma H, Shimizu K, Takenami T, Sugie H, Kawakami T
- Journal Title
  
  Br J Anaesth 101(5)
  
  Pages: 659-665
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591418
[Journal Article] Clonidine prevents neurotoxic effects of lidocaine in culutred mouse dorsal root gang ; lion neurons.2008
- Author(s)
  Shimizu K, Hiruma H, Kawakami T, Hoka S
- Journal Title
  
  The Kitasato Medical Journal 38
  
  Pages: 37-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591418
[Journal Article] Vesicle disruption, plasma membrane bleb formation, and acute cell death caused by illumination with blue light in acridine orange-loaded malignant melanoma cells2007
- Author(s)
  Hiruma H, Katakura T, Takenami T, Igawa S, Kanoh M, Fujimura T, Kawakami T
- Journal Title
  
  Journal of Photochemistry and Photobiology B Biology 86 (1)
  
  Pages: 1-8
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17500260
[Journal Article] Vesicle disruption, plasma membrane bleb formation, and acute cell death caused by illumination with blue light in acridine orange-loaded malignant melanoma cells2007
- Author(s)
  Hiruma H, Katakura T, Takenami T, Igawa S, Kanoh M, Fujimura T, Kawakami T
- Journal Title
  
  Journal of Photochemistry and Photobiology B, Biology 86(1)
  
  Pages: 1-8
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17500260
[Journal Article] Nitric oxide synthase activity in rat gastric mucosa contributes to mucin synthesis elicited by calcitonin gene-related peptide2006
- Author(s)
  Ichikawa T, Kusakabe T, Gono Y, Shikama N, Hiruma H, Kawakami T, Ishihara K
- Journal Title
  
  Biomedical Research (Tokyo, Japan) 27(3)
  
  Pages: 117-124
- NAID
  130004470657
- Data Source
  KAKENHI-PROJECT-17500260
[Journal Article] Nitric oxide synthase activity in rat gastric mucosa contributes to mucin synthesis elicited by calcitonin gene-related peptide2006
- Author(s)
  Ichikawa T, Kusakabe T, Gono Y, Shikama N, Hiruma H, Kawakami T, Ishihara K
- Journal Title
  
  Biomedical Research (Tokyo, Japan) 27 (3)
  
  Pages: 117-124
- NAID
  130004470657
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17500260
[Journal Article] Nitric oxide synthase activity in rat gastric mucosa contributes to mucin synthesis elicited by calcitonin gene-related peptide2006
- Author(s)
  Ichikawa T, Kusakabe T, Gono Y, Shikams N, Hiruma H, Kawakami T, Ishihara K
- Journal Title
  
  Biomedical Research (Tokyo, Japan) 27(3)
  
  Pages: 117-124
- NAID
  130004470657
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17500260
[Journal Article] Effects of soluble laminin on organelle transport and neurite growth in cultured mouse dorsal root ganglion neurons : difference between primary neurites and branches2005
- Author(s)
  Kohno K, Kawakami T, Hiruma H
- Journal Title
  
  Journal of Cellular Physiology 205(2)
  
  Pages: 253-261
- NAID
  130005448019
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17500260
[Journal Article] Neurotoxicity of intrathecally administered bupivacaine involves the posterior roots/posterior white matter and is milder than lidocaine in rats2005
- Author(s)
  Takenami T, Yagishita S, Murase S, Hiruma H, Kawakami T, Hoka S
- Journal Title
  
  Regional Anesthesia and Pain Medicine 30(5)
  
  Pages: 464-472
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17500260
[Journal Article] Effects of soluble laminin on organelle transport and neurite growth in cultured mouse dorsal root ganglion neurons : difference between primary neurites and branches2005
- Author(s)
  Kohno K, Kawakami T, Hiruma H
- Journal Title
  
  Journal of Cellular Physiology 205 (2)
  
  Pages: 253-261
- NAID
  130005448019
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17500260
[Journal Article] Neurotoxicity of intrathecally administered bupivacaine involves the posterior roots/posterior white matter and is milder than lidocaine in rats.2005
- Author(s)
  Takenami T, Yagishita S, Murase S, Hiruma H, Kawakami T, Hoka S
- Journal Title
  
  Regional Anesthesia and Pain Medicine 30(5)
  
  Pages: 464-472
- Data Source
  KAKENHI-PROJECT-17500260
[Journal Article] Neurotoxicity of intrathecally administered bupivacaine involves the posterior roots/posterior white matter and is milder than lidocaine in rats2005
- Author(s)
  Takenami T, Yagishita S, Murase S, Hiruma H, Kawakami T, Hoka S
- Journal Title
  
  Regional Anesthesia and Pain Medicine 30 (5)
  
  Pages: 464-472
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17500260
[Journal Article] Nitric oxide generated by iNOS reduces deformability of Lewis lung carcinoma cells.2004
- Author(s)
  Igawa S, Hayashi I, Tanaka N, Hiruma H, Majima M, Kawakami T, Hirose M, Masuda N, Kobayashi H.
- Journal Title
  
  Cancer Science 95
  
  Pages: 342-347
- NAID
  10013722547
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15500245
[Journal Article] Aβによる神経軸索輸送の抑制2004
- Author(s)
  比留間弘美
- Journal Title
  
  Clinical Neuroscience 22巻
  
  Pages: 748-749
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15500245
[Journal Article] Nitric oxide generated by iNOS reduces deformability of Lewis lung carcinoma cells.2004
- Author(s)
  Igawa S, Hayashi I, Tanaka N, Hiruma H, Majima M, Kawakami T, Hirose M, Masuda N, Kobayashi H.
- Journal Title
  
  Cancer Science 95(4)
  
  Pages: 342-347
- NAID
  10013722547
- Data Source
  KAKENHI-PROJECT-15500245
[Journal Article] Nitric oxide generated by iNOS reduces deformability of Lewis lung carcinoma cells.2004
- Author(s)
  Igawa, S., Hayashi, I., Tanaka, N., Hiruma, H., Majima, M., Kawakami, T., Hirose, M., Masuda, N., Kobayashi, H.
- Journal Title
  
  Cancer Science 95(4)
  
  Pages: 342-347
- NAID
  10013722547
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15500245
[Journal Article] Aβによる神経軸索輸送の抑制2004
- Author(s)
  比留間弘美
- Journal Title
  
  Clinical Neuroscience 22(7)
  
  Pages: 748-749
- Data Source
  KAKENHI-PROJECT-15500245
[Journal Article] Fatty acids as an energy source for the operation of axoplasmic transport.2003
- Author(s)
  Takenaka T, Hiruma H, Hori H, Hashimoto Y, Ichikawa T, Kawakami T
- Journal Title
  
  Brain Research 972
  
  Pages: 38-43
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15500245
[Journal Article] Fatty acids as an energy source for the operation of axoplasmic transport.2003
- Author(s)
  Takenaka, T., Hiruma, H., Hori, H., Hashimoto, Y., Ichikawa, T., Kawakami, T.
- Journal Title
  
  Brain Research 972(1-2)
  
  Pages: 38-43
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15500245
[Journal Article] Effects of extracellular ATP on axonal transport in cultured mouse dorsal root ganglion neurons.2003
- Author(s)
  Sakama R, Hiruma H, Kawakami T
- Journal Title
  
  Neuroscience 121
  
  Pages: 531-535
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15500245
[Journal Article] Effects of extracellular ATP on axonal transport in cultured mouse dorsal root ganglion neurons.2003
- Author(s)
  Sakama, R., Hiruma, H., Kawakami, T.
- Journal Title
  
  Neuroscience 121(3)
  
  Pages: 531-535
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15500245
[Journal Article] Glutamate and amyloid bet, -protein rapidly inhibit fast axonal transport in cultured rat hippocampal neurons by different mechanisms.2003
- Author(s)
  Hiruma, H., Katakura, T., Takahashi, S., Ichikawa, T., Kawakami, T.
- Journal Title
  
  The Journal of Neuroscience 23(26)
  
  Pages: 8967-8977
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15500245
[Journal Article] Glutamate and amyloid beta-protein rapidly inhibit fast axonal transport in cultured rat hippocampal neurons by different mechanisms2003
- Author(s)
  Hiruma H, Katakura T, Takahashi S, Ichikawa T, Kawakami T
- Journal Title
  
  The Journal of Neuroscience 23
  
  Pages: 8967-8977
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15500245
[Journal Article] Effects of soluble laminin on organelle transport and neurite growth in cultured mouse dorsal root ganglion neurons : difference between primary neurites and branches.
- Author(s)
  Kohno, K., Kawakami, T., Hiruma, H.
- Journal Title
  
  Journal of Cellular Physiology (in press)
- NAID
  130005448019
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15500245
[Journal Article] Effects of Soluble Laminin on Organelle Transport and Neurite Growth in Cultured Mouse Dorsal Root Ganglion Neurons : Difference between Primary Neurites and Branches
- Author(s)
  Kohno K, Kawakami T, Hiruma H
- Journal Title
  
  Journal of Cellular Physiology (発表予定)
- NAID
  130005448019
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15500245
[Journal Article] Effects of Soluble Laminin on Organelle Transport and Neurite Growth in Cultured Mouse Dorsal Root Ganglion Neurons : Difference between Primary Neurites and Branches
- Author(s)
  Kohno K, Kawakami T, Hiruma H
- Journal Title
  
  Journal of Cellular Physiolog (発表予定)
- NAID
  130005448019
- Data Source
  KAKENHI-PROJECT-15500245
[Presentation] Histological analysis of Cauda equina syndrome after intrathecal lidocain neurotoxicity in rat2010
- Author(s)
  Isonaka R, Hiruma H, Katakura T, Kawakami T
- Organizer
  第87回日本生理学会大会
- Place of Presentation
  盛岡市民文化ホール(岩手県)
- Year and Date
  2010-05-19
- Data Source
  KAKENHI-PROJECT-20591418
[Presentation] Non-phosphorylated neurofilaments are more vulnerable to superoxide dismutase inhibition than phosphorylated neurofilaments in rat spinal neurons2010
- Author(s)
  Isonaka R, Hiruma H, Kawakami T
- Organizer
  Neuro2010
- Place of Presentation
  神戸コンベンションセンター(兵庫県)
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-20591418
[Presentation] アクリジンオレンジを負荷した膀胱癌細胞の青色光感受性-新しい膀胱癌治療の探索と構築に向けた基礎的研究2010
- Author(s)
  西盛宏、笹本治子、比留間弘美、岩村正嗣、川上倫、馬場志郎
- Organizer
  第2回アクリジンオレンジ治療研究会
- Place of Presentation
  京都府立医科大学(京都府)
- Year and Date
  2010-12-04
- Data Source
  KAKENHI-PROJECT-20591418
[Presentation] The inhibitory effects of pentobarbital on axonal transport in cultured rat cortical neurons2010
- Author(s)
  Sugie H, Hiruma H, Kawakami T
- Organizer
  第87回日本生理学会大会
- Place of Presentation
  盛岡市民文化ホール(岩手県)
- Year and Date
  2010-05-20
- Data Source
  KAKENHI-PROJECT-20591418
[Presentation] Weak base-induced cytoplasmic vacuoles are formed around individual lysosomes2010
- Author(s)
  Hiruma H, Katakura T, Kawakami T
- Organizer
  第87回日本生理学会大会
- Place of Presentation
  盛岡市民文化ホール(岩手県)
- Year and Date
  2010-05-20
- Data Source
  KAKENHI-PROJECT-20591418
[Presentation] Isolated neuroendocrine cells are capable of spontaneous cell fusion during development2010
- Author(s)
  Hiruma H, Isonaka R, Kawakami T
- Organizer
  Neuro2010
- Place of Presentation
  神戸コンベンションセンター(兵庫県)
- Year and Date
  2010-09-04
- Data Source
  KAKENHI-PROJECT-20591418
[Presentation] Anti-tumor cell effects of excitation of acridine orange with blue light2010
- Author(s)
  Hiruma H
- Organizer
  Symposium on Advanced Biotechnologies & Instrumentations (SABI) 2010
- Place of Presentation
  上海復旦大学(中国)
- Year and Date
  2010-10-24
- Data Source
  KAKENHI-PROJECT-20591418
[Presentation] Amyloid-ss protein-actin complex is more neurotoxic than amyloid-I3 protein alone.2009
- Author(s)
  Hiruma H, Katakura T, Kawakami T
- Organizer
  XXXVI International Congress of Physiological Sciences (IUPS2009)
- Place of Presentation
  京都
- Year and Date
  2009-08-01
- Data Source
  KAKENHI-PROJECT-20591418
[Presentation] Amyloid-β protein-actin complex is moreneurotoxic than amyloid-β protein alone2009
- Author(s)
  Hiruma H, Katakura T, Kawakami T
- Organizer
  The 36th Congress of the International Union of Physiological Sciences
- Place of Presentation
  国立京都国際会館(京都)
- Year and Date
  2009-08-01
- Data Source
  KAKENHI-PROJECT-20591418
[Presentation] Influence of reactive oxygen species and free radicals on in vitro axonal transport2009
- Author(s)
  Isonaka R, Hiruma H, Katakura T, Kawakami T
- Organizer
  The 36th Congress of the International Union of Physiological Sciences
- Place of Presentation
  国立京都国際会館(京都)
- Year and Date
  2009-07-30
- Data Source
  KAKENHI-PROJECT-20591418
[Presentation] 光で誘発されるアクリジンオレンジの抗腫瘍細胞作用とその機序2009
- Author(s)
  比留間弘美
- Organizer
  第1回アクリジンオレンジ治療研究会
- Place of Presentation
  京都府立医科大学(京都)
- Year and Date
  2009-11-28
- Data Source
  KAKENHI-PROJECT-20591418
[Presentation] Comparison of neruotoxic effects of procaine, lidocaine and tetracaine on cultured sensory neurons2009
- Author(s)
  Sugie H, Hiruma H, Takenami T, Katakura T, Kawakami T
- Organizer
  The 36th Congress of the International Union of Physiological Sciences
- Place of Presentation
  国立京都国際会館(京都)
- Year and Date
  2009-07-30
- Data Source
  KAKENHI-PROJECT-20591418
[Presentation] Histological analysis on neurotoxicity of intrathecal ropivacaine, levobupivacaine and procaine in rat spinal model2009
- Author(s)
  Takenami T, Hiruma H, Isonaka R, Kawakami T
- Organizer
  The 36th Congress of the International Union of Physiological Sciences
- Place of Presentation
  国立京都国際会館(京都)
- Year and Date
  2009-07-30
- Data Source
  KAKENHI-PROJECT-20591418
[Presentation] Spontaneous cell fusion in cultured isolated fetal rat supraoptic neurons2009
- Author(s)
  Hiruma H, Isonaka R, Kawakami T
- Organizer
  VIIIth World Congress on Neurohypophysial Hormones
- Place of Presentation
  北九州国際会議場(北九州)
- Year and Date
  2009-09-05
- Data Source
  KAKENHI-PROJECT-20591418
[Presentation] Intracellular localization of synaptophysin in cultured rat hypothalamic supraoptic neurons2009
- Author(s)
  Isonaka R, Hiruma H, Kawakami T
- Organizer
  VIIIth World Congress on Neurohypophysial Hormones
- Place of Presentation
  北九州国際会議場(北九州)
- Year and Date
  2009-09-05
- Data Source
  KAKENHI-PROJECT-20591418
[Presentation] Neurotoxic effects of local anesthetics assessed by Trypan-blue staining and axonal transport impairment in cultured dorsal root ganglion neurons2008
- Author(s)
  Sugie H, Hiruma H, Takenami T, Katakura T, Kawakami T
- Organizer
  Neuroscience 2008
- Place of Presentation
  ワシントンD. C., 米国
- Year and Date
  2008-11-19
- Data Source
  KAKENHI-PROJECT-20591418
[Presentation] Effects of amyloid-ss protein-actin complex on axonal transport in cultured rat hippocampal neurons.2008
- Author(s)
  Hiruma H, Katakura T, Kawakami T
- Organizer
  Neuroscience 2008.
- Place of Presentation
  ワシントン(米国)
- Year and Date
  2008-11-19
- Data Source
  KAKENHI-PROJECT-20591418
[Presentation] Procaine and ropivacaine were less neurotoxic than bupivacaine and lidocaine in in vitoro study2008
- Author(s)
  Takenami T, Hiruma H, Suzuki K, Okamoto T, Kawakami T
- Organizer
  2008 Annual Meeting American Society of Anesthesiologists
- Place of Presentation
  オーランド, 米国
- Year and Date
  2008-10-19
- Data Source
  KAKENHI-PROJECT-20591418
[Presentation] Ropivacaine is much less neurotoxic than levobupivacaine, bupivacaine and procaine in rat spinal model2008
- Author(s)
  Hiruma H, Katakura T, Kawakami T
- Organizer
  Neuroscience 2008
- Place of Presentation
  ワシントンD. C., 米国
- Year and Date
  2008-11-19
- Data Source
  KAKENHI-PROJECT-20591418
[Presentation] Effects of amyloid-β protein-actin complex on axonal transport in cultured rat hippocampal neurons2008
- Author(s)
  Hiruma H, Katakura T, Kawakami T
- Organizer
  Neuroscience 2008
- Place of Presentation
  ワシントンD. C., 米国
- Year and Date
  2008-11-19
- Data Source
  KAKENHI-PROJECT-20591418
[Presentation] Effects of sodium bisulfite on the axon of cultured mouse dorsal root ganglion neuron2008
- Author(s)
  Takenami T, Hiruma H, Kawakami T, Koiso S, Kumaki C
- Organizer
  2008 Annual Meeting American Society of Anesthesiologists
- Place of Presentation
  オーランド, 米国
- Year and Date
  2008-10-19
- Data Source
  KAKENHI-PROJECT-20591418
[Presentation] Angiotensin II enhances amyloid ss-protein-induced impairment of axonal transport.2007
- Author(s)
  Hiruma H, Katakura T, Kawakami T
- Organizer
  Neuroscience 2007.
- Place of Presentation
  サンジエゴ(米国)
- Year and Date
  2007-11-06
- Data Source
  KAKENHI-PROJECT-20591418

1. TANAKA Fukuko (40046066)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. ENDO Yutaka (90194050)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. FUNABASHI Toshiya (70229102)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. ARITA Jun (80128587)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. NISHIHARA Masugi (90145673)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 橋本隆平 (70189512)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

HIRUMA Hiromi 比留間 弘美

Research Projects

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Co-Researchers

Enhancement effects of angiotensin II on amyloid 3-induced axonal impairmentPrincipal Investigator

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Insertion of beta-amyloid protein into the cell membrane followed by actin aggregation and impairment of axonal transportPrincipal Investigator

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β-Amyloid-induced changes in cytoskeletons and impairment of axonal transportPrincipal Investigator

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Inhibition of axonal transport of hippocampal neurons by amyloid proteins: relation to Alzheimer's diseasePrincipal Investigator

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Mechanisms for periodic and synchronized activity of GnRH neuronsPrincipal Investigator

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ラット視床下部単一ニューロンにおけるエストロジェン応答の可変性Principal Investigator

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LHRH神経回路がLHRHパルス発生器である可能性:脳切片記録法による検討Principal Investigator

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黄体形成ホルモン放出ホルモン(LHRH)ニューロン同時発火の機序:LHRHの役割Principal Investigator

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Electrophysiological demonstration of the functional bimorphism of LHRH neurons in rats

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Electrophysiological identification of LHRH neurons that are involved in the LH surge induced by positive feedback action of estrogen.

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[Journal Article] Characteristics of weak base-induced vacuoles formed around individual acidic organelle.2011

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[Journal Article] Rapid inhibitory effect of progesterone on axonal transport in isolated and cultured mouse dorsal root ganglion neurons.2010

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NAID

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[Journal Article] Effects of 4-aminopyridine on organelle movement in cultured mouse dorsal root ganglion neurites2010

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[Journal Article] Rapid inhibitory effect of progesterone on axonal transport in isolated and cultured mouse dorsal root ganglion neurons2010

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HIRUMA Hiromi 比留間弘美