TANIMOTO Mitsune 谷本光音

… Alternative Names

Researcher Number	10240805
Affiliation (based on the past Project Information) *help	2016 – 2017: 岡山大学, 医歯薬学総合研究科, 特命教授 2012 – 2015: 岡山大学, 医歯(薬)学総合研究科, 教授 2014: 岡山大学, 医歯薬学総合研究科, 教授 2009 – 2011: 岡山大学, 大学院・医歯薬学総合研究科, 教授 2006 – 2007: 岡山大学, 大学院・医歯学総合研究科, 教授 … More
Review Section/Research Field	Principal Investigator Hematology / Hematology Except Principal Investigator Hematology / Hematology / Biological Sciences / General fisheries
Keywords	Principal Investigator ヒト白血病 / AAV / 遺伝子治療 / 遺伝子導入 / AAVベクター / gene therapy / 造血幹細胞移植 / 免疫療法 / 細胞療法 / 細胞障害性 … More Except Principal Investigator Ryudocan / GATA-2 / cDNA / GVHD / GVL / 転写因子 / PML / 造血幹細胞 / 移植片対宿主病 / ヘパラン硫酸 / Heparan Sulfate / Proteoglycan / 血液流動性 / 血管内皮 / SEREX / CEV / SYK / Ikaros / graft-versus-host disease / graft-versus-leukemia / FTY720 / activation-induced cell death / MyD88 / TRIF / GATA転写因子 / リン酸化 / MAPキナーゼ / 分化 / HIV / TAT / 転写活性 / タンパク質間相互作用 / p300 / 同種造血幹細胞移植 / 慢性GVHD / レチノイド / 血友病B / 遺伝子治療 / レトロウィルスベクター / 第IX因子発現 / マウス線維芽細胞 / VII因子 / レトロウイルスベクター / 第IX因子 / レトロウイルスベクタ- / factor IX / expression vector / retroviral vector / pL9RNL / gene therapy / プロラオグリカン / 遺伝子座 / プロテオグリカン / 1型膜蛋白 / Chromosomal Location / 免疫組織染色 / 特異抗体 / Inhibition radioimmuno assay / alternative polyadenylation / ヒト染色体20q12 / Endothelial cell / Immuno-histochemistry / 血栓性素因 / protein S欠損症 / 分泌異常 / ヘパラン硫酸プロテオグリカン / Ryudocan遺伝子 / プロモーター活性 / 生理的凝固阻止因子 / プロテインC / プロテインS / Thrombophilia / protein C deficiency / protein S deficiency / impaired secretion / endothelium / heparan sulfate proteoglycan / ryudocan gene / promoter activity / ワクチン / 遺伝子銃 / DNAワクチン / PDGFR / チロシンリン酸化 / マンノース / デンドリマー / DC / SFV / Vaccine / Gene Gun / DNA Vaccine / 造血器腫瘍 / hematologic malignancy / transcription factor / sphingosin-1-phosphate / plasmacytoid dendritic cell / graft-versus-hostdisease / dendritic cell / lymph nodes / sphingosin-1-nhoshate / plasmacvtoid dendritic cell / 抗原提示細胞 / GVL効果 / antigen presenting cells Less

Low-dose IL-2 therapy to maintain Treg homeostasis under the use of calcineurin inhibitorPrincipal Investigator
- Principal Investigator
  
  Tanimoto Mitsune
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Okayama University
role of HMGB-1-RAGE pathway on acute GVHD
- Principal Investigator
  
  MAEDA Yoshinobu
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Okayama University
The role of PD1 pathway on tolerance after allogeneic transplantationPrincipal Investigator
- Principal Investigator
  
  TANIMOTO Mitsune
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Okayama University
Synthetic Retinoid Am80 Ameliorates Chronic Graft-Versus-Host Disease by Downregulating Th1 and Th17
- Principal Investigator
  
  MAEDA Yoshinobu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Okayama University
Reduced allostimulatory activity of host antigen-presenting cells regulates the severity of graft-versus-host disease while preserving a graft-versus-leukemia effect
- Principal Investigator
  
  MAEDA Yoshinobu
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Okayama University
Comprehensive analysis of role of dendritic cells and target cells in graft-versus-host disease and graft-versus-leukemia
- Principal Investigator
  
  TESHIMA Takanori
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Kyushu University
Molecular analysis of Ikaros gene family in hematologic malignancy
- Principal Investigator
  
  ISHIMARU Fumihiko
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  OKAYAMA UNIVERSITY
細胞障害性Tリンパ球を模した細胞障害性ゼラチンビーズの開発Principal Investigator
- Principal Investigator
  
  谷本光音
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  Nagoya University
Novel immunotherapy for Hematological Malignancy
- Principal Investigator
  
  SAITO Hidehiko
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Hematology
- Research Institution
  Nagoya University
転写因子とcofactorによる造血幹細胞分化モデル:GATA-2とPMLの結合
- Principal Investigator
  
  齋藤英彦
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
造血幹細胞においてGATA-2遺伝子産物と機能的に結合する蛋白の分離同定
- Principal Investigator
  
  齋藤英彦
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Nagoya University
HIV転写調節機構:造血幹細胞におけるGATA-2による制御
- Principal Investigator
  
  TAKAMATSU Junki
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Nagoya University
Gene Therapy Using rAAV Vector Against Hematological Disorders : From Basic Science To Clinical Application.Principal Investigator
- Principal Investigator
  
  TANIMOTO Mitsune
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University
GATA転写因子と造血細胞の増殖、分化および造血器腫瘍の成因に関する研究
- Principal Investigator
  
  SAITO Hidehiko
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Nagoya University
Molecular Biological Analysis for Mechanism of Thombosis Regulation and Its APlication for Clinical Desease.
- Principal Investigator
  
  SAITO Hidehiko
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University
Basic research of Adeno-associated virus (AAV) mediated gene transfer against human leukemia.Principal Investigator
- Principal Investigator
  
  TANIMOTO Mitsune
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  NAGOYA UNIVERSITY,SCHOOL OF MEDICINE
Molecular and Pathological Analysis of Anticoagulant Heparan Sulfate Proteoglycan from Endothelial Cell
- Principal Investigator
  
  SAITO Hidehiko
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University
Molecular and Pathological Analysis of Anticoagulant Heparan Sulfate Proteoglycan from Endothelial Cell
- Principal Investigator
  
  TAKAMATSU Junki
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General fisheries
- Research Institution
  Nagoya University
Dectection of leukemia-associate antioncogene located on the long-arm of human chromosome 9.Principal Investigator
- Principal Investigator
  
  TANIMOTO Mitsune
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University
Investigation on gene therapy for congenital bleeding tendency
- Principal Investigator
  
  SAITO Hidehiko
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University

All 2017 2016 2013 2010 2007

All Journal Article Presentation

[Journal Article] PD-1 modulates regulatory T-cell homeostasis during low-dose interleukin-2 therapy.2017
- Author(s)
  Asano T, Meguri Y, Yoshioka T, Kishi Y, Iwamoto M, Nakamura M, Sando Y, Yagita H, Koreth J, Kim HT, Alyea EP, Armand P, Cutler CS, Ho VT, Antin JH, Soiffer RJ, Maeda Y, Tanimoto M, Ritz J, Matsuoka KI.
- Journal Title
  
  Blood
  
  Volume: 129 Pages: 2186-2197
- DOI
  10.1182/blood-2016-09-741629
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461449, KAKENHI-PROJECT-15K09504
[Journal Article] Treatment of thrombotic microangiopathy after hematopoietic stem cell transplantation with recombinant human soluble thrombomodulin.2016
- Author(s)
  Fujiwara H, Maeda Y, Sando Y, Nakamura M, Tani K, Ishikawa T, Nishimori H, Matsuoka K, Fujii N, Kondo E, Tanimoto M.
- Journal Title
  
  Transfusion
  
  Volume: 56 Pages: 886-92
- DOI
  10.1111/trf.13437
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09504, KAKENHI-PROJECT-26461449
[Journal Article] Vigorous inflammatory responses in noninfectious pulmonary complication induced by donor lymphocyte infusion.2016
- Author(s)
  Nishie M, Fujii N, Mimura Y, Asano T, Mimura-Kimura Y, Aoe K, Aoe M, Nakashima H, Fujiwara H, Nishimori H, Matsuoka K, Kondo E, Maeda Y, Tanimoto M.
- Journal Title
  
  Transfusion
  
  Volume: 56 Pages: 231-6
- DOI
  10.1111/trf.13283
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09504, KAKENHI-PROJECT-26461449
[Journal Article] Alloantigen expression on non-hematopoietic cells reduces graft-versus-leukemia effects in mice.2010
- Author(s)
  Asakura S, Hashimoto D, Takashima S, Sugiyama H, Maeda Y, Akashi K, Tanimoto M, Teshima T.
- Journal Title
  
  J Clin Invest.
  
  Volume: 120 Pages: 2370-2378
- NAID
  130004505744
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591244
[Presentation] B7H1 expression on recipient regulate the frequency of IL-17+ IFNg+ T cells and contribute to the pathogenesis of cGVHD.2013
- Author(s)
  H Fujiwara, K Kobayashi, H Nishimori, M Nishinohara, S Okamoto, K Matsuoka, E Kondo, N Fujii, K Shinagawa, M Tanimoto and Y Maeda.
- Organizer
  ASBMT tandem meeting
- Place of Presentation
  Solt lake cuty, USA
- Data Source
  KAKENHI-PROJECT-24591425
[Presentation] Donor Th17 and Th1 Contribute to Chronic Graft-Versus-Host Disease2010
- Author(s)
  H Nishimori, R Sugiyama, K Kobayashi, Y Yamasuji, S Kadohisa, K Takeuchi, Y Iwakura, M Tanimoto, Y Maeda
- Organizer
  アメリカ血液学会
- Place of Presentation
  フロリダ
- Year and Date
  2010-12-06
- Data Source
  KAKENHI-PROJECT-21591244
[Presentation] Breast-feeding mediates feto-matemal tolerance and improves outcome of allogeneic bone marrow transplantation.2007
- Author(s)
  Aoyama K, Matsuoka K, Hashimoto D, Ichinohe T, Harada M, Tanimoto M, Teshima T
- Organizer
  49^<th> Annual Meeting of The American Society of Hematology
- Place of Presentation
  Atlanta, USA
- Data Source
  KAKENHI-PROJECT-17390280
[Presentation] Host plasmacytoid or conventional dendritic cells alone are sufficient to initiate graft-versus-host disease2007
- Author(s)
  M., Koyama, D., Hashimoto, K., Aoyama, K., Matsuoka, K., Karube, K., Takeda, K., Ohshima, M., Tanimoto, M., Harada, T., Teshima
- Organizer
  49th Annual Meeting of ASH
- Place of Presentation
  Atlanta, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390280
[Presentation] Host plasmacytoid or conventional dendritic cells alone are sufficient to initiate graft-versus-host disease.2007
- Author(s)
  Koyama M, Hashimoto D, Aoyama K, Matsuoka K, Karube K, Takeda K, Ohshima K, Tanimoto M, Harada M, Teshima T
- Organizer
  49^<th> Annual Meeting of The American Society of Hematology
- Place of Presentation
  Atlanta, USA
- Data Source
  KAKENHI-PROJECT-17390280

1. SAITO Hidehiko (20153819)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
2. 唐渡雅行

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. MAEDA Yoshinobu (60403474)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
4. TAKAMATSU Junki (80221365)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. KOJIMA Tetsuhito (40161913)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. EMI Nobuhiko (30185144)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. KOUNO Akio

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 都築忍

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. NAOE Tomoki (50217634)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. ISHIMARU Fumihiko (50284097)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. TESHIMA Takanori (40284096)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
12. 浜口道成 (90135351)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 松岡賢市 (90432640)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
14. TAKEO Takaaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. IIJIMA Narikazu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 横澤敏也

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 松岡明

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

TANIMOTO Mitsune 谷本 光音

TANIMOTO Mistune 谷本 光音

Research Projects

Research Products

Co-Researchers

Low-dose IL-2 therapy to maintain Treg homeostasis under the use of calcineurin inhibitorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of PD1 pathway on tolerance after allogeneic transplantationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

細胞障害性Tリンパ球を模した細胞障害性ゼラチンビーズの開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Gene Therapy Using rAAV Vector Against Hematological Disorders : From Basic Science To Clinical Application.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

TANIMOTO Mitsune 谷本光音

TANIMOTO Mistune 谷本光音