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TANIMOTO Mitsune  谷本 光音

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TANIMOTO Mistune  谷本 光音

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Researcher Number 10240805
Affiliation (based on the past Project Information) *help 2016 – 2017: 岡山大学, 医歯薬学総合研究科, 特命教授
2012 – 2015: 岡山大学, 医歯(薬)学総合研究科, 教授
2014: 岡山大学, 医歯薬学総合研究科, 教授
2009 – 2011: 岡山大学, 大学院・医歯薬学総合研究科, 教授
2006 – 2007: 岡山大学, 大学院・医歯学総合研究科, 教授 … More
2006 – 2007: 岡山大学, 大学院・医歯薬学総合研究科, 教授
2005: 岡山大学, 大学院・医歯学給合研究科, 教授
2002 – 2003: 岡山大学, 大学院・医歯学総合研究科, 教授
1998 – 2000: School of Medicine, Nagoya University Assistant Professor, 医学部, 講師
1995 – 1998: 名古屋大学, 医学部, 助手
1994: Nagoya University School of Medicine, Assistant Professor
1992 – 1993: Nagoya University School of Medicine, Assistant Professor, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Hematology / Hematology
Except Principal Investigator
Hematology / Hematology / Biological Sciences / General fisheries
Keywords
Principal Investigator
ヒト白血病 / AAV / 遺伝子治療 / 遺伝子導入 / AAVベクター / gene therapy / 造血幹細胞移植 / 免疫療法 / 細胞療法 / 細胞障害性 … More / Tリンパ球 / 抗体療法 / イムノビーズ / アポトーシス / Fas-FasL / 人工細胞 / GVHD / GVHD / 分子生物学 / 遺伝子欠損 / 癌抑制性遺伝子 / 第9染色体 / 染色体欠失 / 染色体欠欠 / 遺伝子欠失 / 遺伝子クローニング / Human leukemia / Molecular biology / Gene deletion / Tumor suppressor gene / Chromosome 9 / Chromosome defect / 造血幹細胞 / ウイルスベクター / 白血病細胞 / AAV mediated gene transfer / human leukemia / hematopoietic stem cells / viral vector / 造血細胞株 / 細胞治療 / 細胞培養 / 血液悪性腫瘍 / GVL効果 / GLV効果 / ドナーリンパ球輸注 / リコンビナント / adeno associate virus / gene transduction / hematopoetic cell / cell therapy / cell culture / GVL effect / hematopoietic neoplasms / 制御性T細胞 / 移植片対宿主病 / 免疫寛容 / 同種造血幹細胞移植 … More
Except Principal Investigator
Ryudocan / GATA-2 / cDNA / GVHD / GVL / 転写因子 / PML / 造血幹細胞 / 移植片対宿主病 / ヘパラン硫酸 / Heparan Sulfate / Proteoglycan / 血液流動性 / 血管内皮 / SEREX / CEV / SYK / Ikaros / graft-versus-host disease / graft-versus-leukemia / FTY720 / activation-induced cell death / MyD88 / TRIF / GATA転写因子 / リン酸化 / MAPキナーゼ / 分化 / HIV / TAT / 転写活性 / タンパク質間相互作用 / p300 / 同種造血幹細胞移植 / 慢性GVHD / レチノイド / 血友病B / 遺伝子治療 / レトロウィルスベクター / 第IX因子発現 / マウス線維芽細胞 / VII因子 / レトロウイルスベクター / 第IX因子 / レトロウイルスベクタ- / factor IX / expression vector / retroviral vector / pL9RNL / gene therapy / プロラオグリカン / 遺伝子座 / プロテオグリカン / 1型膜蛋白 / Chromosomal Location / 免疫組織染色 / 特異抗体 / Inhibition radioimmuno assay / alternative polyadenylation / ヒト染色体20q12 / Endothelial cell / Immuno-histochemistry / 血栓性素因 / protein S欠損症 / 分泌異常 / ヘパラン硫酸プロテオグリカン / Ryudocan遺伝子 / プロモーター活性 / 生理的凝固阻止因子 / プロテインC / プロテインS / Thrombophilia / protein C deficiency / protein S deficiency / impaired secretion / endothelium / heparan sulfate proteoglycan / ryudocan gene / promoter activity / ワクチン / 遺伝子銃 / DNAワクチン / PDGFR / チロシンリン酸化 / マンノース / デンドリマー / DC / SFV / Vaccine / Gene Gun / DNA Vaccine / 造血器腫瘍 / hematologic malignancy / transcription factor / sphingosin-1-phosphate / plasmacytoid dendritic cell / graft-versus-hostdisease / dendritic cell / lymph nodes / sphingosin-1-nhoshate / plasmacvtoid dendritic cell / 抗原提示細胞 / GVL効果 / antigen presenting cells Less
  • Research Projects

    (20 results)
  • Research Products

    (9 results)
  • Co-Researchers

    (17 People)
  •  Low-dose IL-2 therapy to maintain Treg homeostasis under the use of calcineurin inhibitorPrincipal Investigator

    • Principal Investigator
      Tanimoto Mitsune
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Okayama University
  •  role of HMGB-1-RAGE pathway on acute GVHD

    • Principal Investigator
      MAEDA Yoshinobu
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Okayama University
  •  The role of PD1 pathway on tolerance after allogeneic transplantationPrincipal Investigator

    • Principal Investigator
      TANIMOTO Mitsune
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Okayama University
  •  Synthetic Retinoid Am80 Ameliorates Chronic Graft-Versus-Host Disease by Downregulating Th1 and Th17

    • Principal Investigator
      MAEDA Yoshinobu
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Okayama University
  •  Reduced allostimulatory activity of host antigen-presenting cells regulates the severity of graft-versus-host disease while preserving a graft-versus-leukemia effect

    • Principal Investigator
      MAEDA Yoshinobu
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Okayama University
  •  Comprehensive analysis of role of dendritic cells and target cells in graft-versus-host disease and graft-versus-leukemia

    • Principal Investigator
      TESHIMA Takanori
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      Kyushu University
  •  Molecular analysis of Ikaros gene family in hematologic malignancy

    • Principal Investigator
      ISHIMARU Fumihiko
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      OKAYAMA UNIVERSITY
  •  細胞障害性Tリンパ球を模した細胞障害性ゼラチンビーズの開発Principal Investigator

    • Principal Investigator
      谷本 光音
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Hematology
    • Research Institution
      Nagoya University
  •  Novel immunotherapy for Hematological Malignancy

    • Principal Investigator
      SAITO Hidehiko
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Hematology
    • Research Institution
      Nagoya University
  •  転写因子とcofactorによる造血幹細胞分化モデル:GATA-2とPMLの結合

    • Principal Investigator
      齋藤 英彦
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      Nagoya University
  •  造血幹細胞においてGATA-2遺伝子産物と機能的に結合する蛋白の分離同定

    • Principal Investigator
      齋藤 英彦
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Nagoya University
  •  HIV転写調節機構:造血幹細胞におけるGATA-2による制御

    • Principal Investigator
      TAKAMATSU Junki
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Nagoya University
  •  Gene Therapy Using rAAV Vector Against Hematological Disorders : From Basic Science To Clinical Application.Principal Investigator

    • Principal Investigator
      TANIMOTO Mitsune
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Nagoya University
  •  GATA転写因子と造血細胞の増殖、分化および造血器腫瘍の成因に関する研究

    • Principal Investigator
      SAITO Hidehiko
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Nagoya University
  •  Molecular Biological Analysis for Mechanism of Thombosis Regulation and Its APlication for Clinical Desease.

    • Principal Investigator
      SAITO Hidehiko
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      Nagoya University
  •  Basic research of Adeno-associated virus (AAV) mediated gene transfer against human leukemia.Principal Investigator

    • Principal Investigator
      TANIMOTO Mitsune
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      NAGOYA UNIVERSITY,SCHOOL OF MEDICINE
  •  Molecular and Pathological Analysis of Anticoagulant Heparan Sulfate Proteoglycan from Endothelial Cell

    • Principal Investigator
      SAITO Hidehiko
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      Nagoya University
  •  Molecular and Pathological Analysis of Anticoagulant Heparan Sulfate Proteoglycan from Endothelial Cell

    • Principal Investigator
      TAKAMATSU Junki
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General fisheries
    • Research Institution
      Nagoya University
  •  Dectection of leukemia-associate antioncogene located on the long-arm of human chromosome 9.Principal Investigator

    • Principal Investigator
      TANIMOTO Mitsune
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Nagoya University
  •  Investigation on gene therapy for congenital bleeding tendency

    • Principal Investigator
      SAITO Hidehiko
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      Nagoya University

All 2017 2016 2013 2010 2007

All Journal Article Presentation

  • [Journal Article] PD-1 modulates regulatory T-cell homeostasis during low-dose interleukin-2 therapy.2017

    • Author(s)
      Asano T, Meguri Y, Yoshioka T, Kishi Y, Iwamoto M, Nakamura M, Sando Y, Yagita H, Koreth J, Kim HT, Alyea EP, Armand P, Cutler CS, Ho VT, Antin JH, Soiffer RJ, Maeda Y, Tanimoto M, Ritz J, Matsuoka KI.
    • Journal Title

      Blood

      Volume: 129 Pages: 2186-2197

    • DOI

      10.1182/blood-2016-09-741629

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461449, KAKENHI-PROJECT-15K09504
  • [Journal Article] Treatment of thrombotic microangiopathy after hematopoietic stem cell transplantation with recombinant human soluble thrombomodulin.2016

    • Author(s)
      Fujiwara H, Maeda Y, Sando Y, Nakamura M, Tani K, Ishikawa T, Nishimori H, Matsuoka K, Fujii N, Kondo E, Tanimoto M.
    • Journal Title

      Transfusion

      Volume: 56 Pages: 886-92

    • DOI

      10.1111/trf.13437

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09504, KAKENHI-PROJECT-26461449
  • [Journal Article] Vigorous inflammatory responses in noninfectious pulmonary complication induced by donor lymphocyte infusion.2016

    • Author(s)
      Nishie M, Fujii N, Mimura Y, Asano T, Mimura-Kimura Y, Aoe K, Aoe M, Nakashima H, Fujiwara H, Nishimori H, Matsuoka K, Kondo E, Maeda Y, Tanimoto M.
    • Journal Title

      Transfusion

      Volume: 56 Pages: 231-6

    • DOI

      10.1111/trf.13283

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09504, KAKENHI-PROJECT-26461449
  • [Journal Article] Alloantigen expression on non-hematopoietic cells reduces graft-versus-leukemia effects in mice.2010

    • Author(s)
      Asakura S, Hashimoto D, Takashima S, Sugiyama H, Maeda Y, Akashi K, Tanimoto M, Teshima T.
    • Journal Title

      J Clin Invest.

      Volume: 120 Pages: 2370-2378

    • NAID

      130004505744

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591244
  • [Presentation] B7H1 expression on recipient regulate the frequency of IL-17+ IFNg+ T cells and contribute to the pathogenesis of cGVHD.2013

    • Author(s)
      H Fujiwara, K Kobayashi, H Nishimori, M Nishinohara, S Okamoto, K Matsuoka, E Kondo, N Fujii, K Shinagawa, M Tanimoto and Y Maeda.
    • Organizer
      ASBMT tandem meeting
    • Place of Presentation
      Solt lake cuty, USA
    • Data Source
      KAKENHI-PROJECT-24591425
  • [Presentation] Donor Th17 and Th1 Contribute to Chronic Graft-Versus-Host Disease2010

    • Author(s)
      H Nishimori, R Sugiyama, K Kobayashi, Y Yamasuji, S Kadohisa, K Takeuchi, Y Iwakura, M Tanimoto, Y Maeda
    • Organizer
      アメリカ血液学会
    • Place of Presentation
      フロリダ
    • Year and Date
      2010-12-06
    • Data Source
      KAKENHI-PROJECT-21591244
  • [Presentation] Breast-feeding mediates feto-matemal tolerance and improves outcome of allogeneic bone marrow transplantation.2007

    • Author(s)
      Aoyama K, Matsuoka K, Hashimoto D, Ichinohe T, Harada M, Tanimoto M, Teshima T
    • Organizer
      49^<th> Annual Meeting of The American Society of Hematology
    • Place of Presentation
      Atlanta, USA
    • Data Source
      KAKENHI-PROJECT-17390280
  • [Presentation] Host plasmacytoid or conventional dendritic cells alone are sufficient to initiate graft-versus-host disease2007

    • Author(s)
      M., Koyama, D., Hashimoto, K., Aoyama, K., Matsuoka, K., Karube, K., Takeda, K., Ohshima, M., Tanimoto, M., Harada, T., Teshima
    • Organizer
      49th Annual Meeting of ASH
    • Place of Presentation
      Atlanta, USA
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390280
  • [Presentation] Host plasmacytoid or conventional dendritic cells alone are sufficient to initiate graft-versus-host disease.2007

    • Author(s)
      Koyama M, Hashimoto D, Aoyama K, Matsuoka K, Karube K, Takeda K, Ohshima K, Tanimoto M, Harada M, Teshima T
    • Organizer
      49^<th> Annual Meeting of The American Society of Hematology
    • Place of Presentation
      Atlanta, USA
    • Data Source
      KAKENHI-PROJECT-17390280
  • 1.  SAITO Hidehiko (20153819)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 2.  唐渡 雅行
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 3.  MAEDA Yoshinobu (60403474)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 3 results
  • 4.  TAKAMATSU Junki (80221365)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  KOJIMA Tetsuhito (40161913)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  EMI Nobuhiko (30185144)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  KOUNO Akio
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  都築 忍
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  NAOE Tomoki (50217634)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  ISHIMARU Fumihiko (50284097)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  TESHIMA Takanori (40284096)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 12.  浜口 道成 (90135351)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  松岡 賢市 (90432640)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 14.  TAKEO Takaaki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  IIJIMA Narikazu
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  横澤 敏也
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  松岡 明
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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