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AZUMA Hiroyuki
東 博之
Connect your ORCID iD
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Researcher Number
10241275
Other IDs
Affiliation (based on the past Project Information)
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2006: The University of Tokushima, Institute of Health Biosciences, Associated professor, 大学院ヘルスバイオサイエンス研究部, 助教授
2004 – 2005: 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 助教授
1999 – 2003: 徳島大学, 医学部, 助教授
1998: 徳島大学, 医学部, 講師
1998: University of Tokushima, University Hospital, Assistant Professor, 医学部附属病院, 講師
1993 – 1997: 徳島大学, 医学部・附属病院, 助手
1992 – 1993: 徳島大学, 医学部附属病院, 助手
Review Section/Research Field
Principal Investigator
Hematology
/
Circulatory organs internal medicine
/
内分泌・代謝学
/
Circulatory organs internal medicine
Except Principal Investigator
Hematology
/
Neurology
/
Metabolomics
/
Circulatory organs internal medicine
/
Circulatory organs internal medicine
Keywords
Principal Investigator
トロンビン / 動脈硬化 / リポプロテイン(a) / アポリポプロテイン(a) / 高脂血症 / Growth hormone-releasing hormone / Sandwich assay / HHT / Smad / ヘパリンコファクターII
…
More
/ ノックアウトマウス / heparin cofactor II / atherosclerosis / thrombin / vascular smooth muscle cell / トロンビンレセプター / ラジオイムノアッセイ / 合成ペプチド / DIC / 下肢静脈血栓症 / 心筋梗塞 / 転写 / ルシフェラーゼ / ニコチン酸 / 転写活性 / IL-6 / ATRA / Somatostatin / 酵素免疫測定法 / 超高感度 / アビジン / ビオチン / Growth hormone-releasing hormoe / Somatostain / Enzyme immunoassay / Urtrasensitive / Streptavidin / Biotin / TGF-β / エンドグリン / HGF-β / 遺伝性出血性毛細血管拡張症 / 毛細血管 / TGF-beta / Endoglin / トロンピン / 血管平滑筋 / デルマタン硫酸 / dermatan sulfate / knockout mouse / 冠動脈インターベンション / 血管リモデリング / 血管平滑筋細胞 / トロンビン受容体 / PCI / PAR / coronary intervention / knockout mice / vascular remodeling / thrombin receptor
…
More
Except Principal Investigator
先天性ヒスチジンリッチグリコプロテイン欠乏症 / 先天性血栓性素因 / 遺伝子異常 / 動脈硬化 / アスピリン / 血管内皮細胞 / atherosclerosis / aspirin / ミトコンドリア障害 / 活性酸素 / reactive oxygen species / BMK1 / ERK5 / KLF2 / プラスミノゲン / 先天性プラスミノゲン欠乏症 / 発症機構 / 病態生理 / ヒスチジンリッチグリコプロテイン / 血栓症 / リポ蛋白(a) / アポ蛋白(a) / 転写因子 / 肝細胞 / 血管内及細胞 / IL-6 / 転写活性 / lipoprotein (a) / apolipoprotein (a) / transcriptional factor / hepatocyte / endothelial cell / ステロイド筋症 / ミトコンドリア脳筋症 / Mitochondrial damage / Corticosteroid myopathy / Mitochondrial encephalomyopathy / Reactive oxigen species / トロンビン / ミトコンドリア / 電子伝達系 / vascular endothelial cells / thrombin / mitochondria / repiratory chain / 活性酸素種 / スーパーオキサイドジスムターゼ / アポトーシス / グルココルチコイド / グルココルチコイド受容体 / 神経細胞 / 筋細胞 / superoxide dismutase / mitochondrial dysfunction / apoptosis / 血管内皮機能 / スタチン / 炎症 / 一酸化窒素合成酵素 / 多面的作用 / PPARγ / VCAM-1 / vascular endothelial function / statin / inflammation / nitric oxide synthase / pleiotropic effect
Less
Research Projects
(
15
results)
Co-Researchers
(
12
People)
Project Start Year (Newest)
Project Start Year (Oldest)
Novel regulatory mechanism of vascular endothelial function mediated by BMK1/ERK5 and its application for anti-atherosclerosis therapy
Principal Investigator
AKAIKE Masashi
Project Period (FY)
2005 – 2006
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Circulatory organs internal medicine
Research Institution
The University of Tokushima
Novel anti-atherosclerotic and anti-thrombotic action of plasma heparin cofactor II
Principal Investigator
Principal Investigator
AZUMA Hiroyuki
Project Period (FY)
2004 – 2005
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Circulatory organs internal medicine
Research Institution
The University of Tokushima
Mitochondrial dysfunction mediated by the activation of glucocorticoid receptor
Principal Investigator
TAKAO Mitsuki
Project Period (FY)
2002 – 2003
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Neurology
Research Institution
The University of Tokushima
Mitochondrial damage mediated by reactive oxygen species : A study in corticosteroid myopathy and mitochondrial encephalomyopathies
Principal Investigator
MITSUI Takao
Project Period (FY)
2000 – 2001
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Neurology
Research Institution
The University of Tokushima
Thrombin-induoed vascular injury through the overproduction of reactive oxygen species
Principal Investigator
AKAIKE Masashi
Project Period (FY)
2000 – 2001
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Circulatory organs internal medicine
Research Institution
The University of Tokushima
Role and clinical significance of heparin cofactor II as an anti-atherosclerotic factor
Principal Investigator
Principal Investigator
AZUMA Hiroyuki
Project Period (FY)
1999 – 2000
Research Category
Grant-in-Aid for Scientific Research (C)
Research Institution
University of Tokushima
Development of novel agents using the method of modulating the transcriptional activity of apo (a) gene
Principal Investigator
MATSUMOTO Toshio
Project Period (FY)
1998 – 2000
Research Category
Grant-in-Aid for Scientific Research (B).
Research Field
Metabolomics
Research Institution
University of Tokushima
先天性ヒスチジンリッチグリコプロテイン欠乏症の病態生理，遺伝子異常および発症機構
Principal Investigator
重清 俊雄
Project Period (FY)
1997 – 1999
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Hematology
Research Institution
The University of Tokushima
Elucidation of genetic abnormality and molecular pathogenesis of hereditary hemorrhagic telangiectasia
Principal Investigator
Principal Investigator
AZUMA Hiroyuki
Project Period (FY)
1997 – 1998
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Hematology
Research Institution
University of Tokushima
血栓症の危険因子である高Lp(a)血症の治療薬のスクリーニングと作用機序の解明
Principal Investigator
Principal Investigator
東 博之
Project Period (FY)
1996
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Hematology
Research Institution
The University of Tokushima
先天性プラスミノゲン欠乏症の遺伝子異常、発症機構および病態生理に関する研究
Principal Investigator
重清 俊雄
Project Period (FY)
1995
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Hematology
Research Institution
The University of Tokushima
高リポ蛋白(a)血症に対する治療薬の作用機序の解明と新しい治療薬のスクリーニング
Principal Investigator
Principal Investigator
東 博之
Project Period (FY)
1995
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Circulatory organs internal medicine
Research Institution
The University of Tokushima
世界初の先天性ヒスチジンリッチグリコプロテイン欠乏症の遺伝子異常と病態生理
Principal Investigator
重清 俊雄
Project Period (FY)
1994
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Hematology
Research Institution
The University of Tokushima
トロンビンレセプター活性化放出ペプチドのラジオイムノアッセイの開発と臨床応用
Principal Investigator
Principal Investigator
東 博之
Project Period (FY)
1994
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Hematology
Research Institution
The University of Tokushima
Development of urtrasensitive noncompetitive enzyme immunoassay for hypothalamic hormone and it's clinical application
Principal Investigator
Principal Investigator
AZUMA Hiroyuki
Project Period (FY)
1992 – 1993
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
内分泌・代謝学
Research Institution
The University of Tokushima
# of Projects (Dsc)
# of Projects (Asc)
1.
AKAIKE Masashi
(90271080)
# of Collaborated Projects:
8 results
# of Collaborated Products:
0 results
2.
MITSUI Takao
(80294726)
# of Collaborated Projects:
5 results
# of Collaborated Products:
0 results
3.
重清 俊雄
(50162582)
# of Collaborated Projects:
5 results
# of Collaborated Products:
0 results
4.
SHUNTANI Yasumi
(10235773)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
5.
MATSUMOTO Toshio
(20157374)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
6.
AIHARA Ken-ichi
(70372711)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
7.
NISHIDA Toshinobu
(50156080)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
8.
YOKOGOSAHI Yutaka
(00253203)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
9.
MIZUSHIMA Jyun
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
10.
白川 光雄
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
11.
金川 泰彦
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
12.
池田 康将
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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