Seki Tamotsu 關保

… Alternative Names

SEKI Tamotsu 關保

關保セキタモツ

関保セキタモツ

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Researcher Number	10245855
Affiliation (Current)	2025: 昭和医科大学, 医学部, 客員教授
Affiliation (based on the past Project Information) *help	2015: 昭和大学, 医学部, 客員教授 2009 – 2014: Showa University, 医学部, 兼任講師 2001: Showa Univ. Sch. Med., Assistant Professor, 医学部, 講師 2000: 昭和大, 医学部, 講師 1999: 昭和大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Ophthalmology / Ophthalmology Except Principal Investigator Ophthalmology
Keywords	Principal Investigator PACAP / TNFα / 緑内障 / Transgenic mouse / Signal transduction / Delayed neuronal cell death / Neurotrophic Factor / Ischemia / Retina / KO mouse … More / Tumor Necrosis Factor-α / 虚血 / 網膜 / 遺伝子欠損マウス / Apoptosis / 免疫 / NMDA / 神経節細胞 / マクロファージ / マイクログリア / 神経保護 / 神経保護作用 / マウス / 網膜神経変性 / 網膜神経幹細胞 / 網膜保護 / 眼組織学 … More Except Principal Investigator マウス / 涙液分泌 / PACAP / ドライアイ / 角膜 / 涙液 / 角膜上皮 / 点眼 / 角膜傷害 / 涙腺 / 眼薬理学 Less

Effect of PACAP for prevention/treatment of dry eye syndrome
- Principal Investigator
  
  NAKAMACHI Tomoya
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  University of Toyama
  Showa University
Neuroprotective effect of PACAP against retinal damage in Glaucoma via immunomodurationPrincipal Investigator
- Principal Investigator
  
  Seki Tamotsu
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Showa University
Mechanism of PACAP-induced tear secretion
- Principal Investigator
  
  NAKAMACHI Tomoya
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Showa University
Effect of PACAP on adult retinal stem cell and the regenerative potential.Principal Investigator
- Principal Investigator
  
  SEKI Tamotsu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Showa University
Functional significance of tumor necrosis factor alpha in inducing retinal ganglion cell death by using gene targeting methodPrincipal Investigator
- Principal Investigator
  
  SHIODA Seiji, 關保 (関保)
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Showa University

All 2016 2015 2014 2013 2012 2011 2010 2009 Other

All Journal Article Presentation Book

[Book] PACAP and neural development. In: Pituitary Adenylate Cyclase Activating Polypeptide – PACAP, (Eds. Reglodi D and Tamas A)2016
- Author(s)
  Watanabe J, Seki T, Shioda S
- Publisher
  New York: Springer Nature (New York)
- Data Source
  KAKENHI-PROJECT-24592681
[Journal Article] Pituitary adenylate cyclase-activating polypeptide (PACAP) is involved in adult mouse hippocampal neurogenesis after stroke.2016
- Author(s)
  Matsumoto M, Nakamachi T, Watanabe J, Sugiyama K, Ohtaki H, Murai N, Sasaki S, Xu Z, Hashimoto H, Seki T, Miyazaki A, Shioda S.
- Journal Title
  
  J Mol Neurosci
  
  Volume: 10 Issue: 2 Pages: 1007-1007
- DOI
  10.1007/s12031-016-0731-x
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10993, KAKENHI-PROJECT-25462309, KAKENHI-PROJECT-24592681, KAKENHI-PROJECT-25462236, KAKENHI-PROJECT-16H02684, KAKENHI-PROJECT-16H05443, KAKENHI-PROJECT-15K15670, KAKENHI-PROJECT-25861289, KAKENHI-PROJECT-16K13054, KAKENHI-PROJECT-16K21372
[Journal Article] 精密かつ体に優しい画像診断装置OCT2013
- Author(s)
  関　　保
- Journal Title
  
  蒲田医師会学術誌
  
  Volume: in press
- Data Source
  KAKENHI-PROJECT-24592681
[Journal Article] 糖尿病網膜症について2013
- Author(s)
  関　　保
- Journal Title
  
  蒲田医師会雑誌
  
  Volume: 91 Pages: 36-36
- Data Source
  KAKENHI-PROJECT-24592681
[Journal Article] PACAP Attenuates NMDA-Induced Retinal Damage in Association with Modulation of the Microglia/Macrophage Status into an Acquired Deactivation Subtype.2013
- Author(s)
  Wada Y, Nakamachi T, Endo K, Seki T, Ohtaki H, Tsuchikawa D, Hori M, Tsuchida M, Yoshikawa A, Matkovits A, Kagami N, Imai N, Fujisaka S, Usui I, Tobe K, Koide R, Takahashi H, Shioda S
- Journal Title
  
  J Mol Neurosci.
  
  Volume: 51(2) Issue: 2 Pages: 493-502
- DOI
  10.1007/s12031-013-0017-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249079, KAKENHI-PROJECT-24592680, KAKENHI-PROJECT-24592681, KAKENHI-PROJECT-25461333, KAKENHI-PROJECT-25462236
[Journal Article] 東京都大田区における緑内障検診について2013
- Author(s)
  関　保、真木剛浩、下村直樹、濱畑和男
- Journal Title
  
  大田区医学会誌
  
  Volume: in press
- Data Source
  KAKENHI-PROJECT-24592681
[Journal Article] Distribution and protective function of pituitary adenylate cyclase-activating polypeptide in the retina.2012
- Author(s)
  Nakamachi Tomoya
- Journal Title
  
  Front Endocrinol (Lausanne)
  
  Volume: 3 Pages: 145-145
- DOI
  10.3389/fendo.2012.00145
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249079, KAKENHI-PROJECT-24592680, KAKENHI-PROJECT-24592681
[Journal Article] 大田区における緑内障検診2012
- Author(s)
  関　保、濱畑和男、下村直樹、籾木伊津穂、儘田直久
- Journal Title
  
  大田区医学会誌
  
  Volume: 4 Pages: 58-61
- Data Source
  KAKENHI-PROJECT-24592681
[Journal Article] Suppression of rat retinal ganglion cell death by PACAP following transient ischemia induced by high intraocular pressure.2011
- Author(s)
  Seki T, Itoh H, Nakamachi T, Endo K, Wada Y, Nakamura K, Shioda S
- Journal Title
  
  J Mol Neurosci
  
  Volume: 43(1) Pages: 30-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592246
[Journal Article] Neuroprotective effect of PACAP against NMDA-induced retinal damage in the mouse2011
- Author(s)
  Endo K, Nakamachi T, Seki T, Kagami N, Wada Y, Nakamura K, Kishimoto K, Hori M, Tsuchikawa D, Shinntani N, Hashimoto H, Baba A, Koide R, Shioda S
- Journal Title
  
  J Mol Neurosci
  
  Volume: 43(1) Pages: 22-29
- Data Source
  KAKENHI-PROJECT-22791695
[Journal Article] Neuroprotective effect of PACAP against NMDA-induced retinal damage in the mouse.2011
- Author(s)
  Endo K, Nakamachi T, Seki T, Kagami N, Wada Y, Nakamura K, Kishimoto K, Hori M, Tsuchikawa D, Shinntani N, Hashimoto H, Baba A, Koide R, Shioda S
- Journal Title
  
  J Mol Neurosci
  
  Volume: 43(1) Pages: 22-29
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791695
[Journal Article] Suppression of rat retinal ganglion cell death by PACAP following transient ischemia induced by high intraocular pressure2011
- Author(s)
  Seki T, Itoh H, Nakamachi T, Endo K, Wada Y, Nakamura K, Shioda S
- Journal Title
  
  J Mol Neurosci
  
  Volume: 43(1) Pages: 30-34
- Data Source
  KAKENHI-PROJECT-21592246
[Journal Article] Suppression of rat retinal ganglion cell death by PACAP following transient ischemia induced by high intraocular pressure.2011
- Author(s)
  Seki T, Itoh H, Nakamachi T, Endo K, Wada Y, Nakamura K, Shioda S
- Journal Title
  
  J Mol Neurosci
  
  Volume: 43(1) Pages: 30-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791695
[Journal Article] Neuroprotective effect of PACAP against NMDA-induced retinal damage in the mouse.2011
- Author(s)
  Endo K, Nakamachi T, Seki T, Kagami N, Wada Y, Nakamura K, Kishimoto K, Hori M, Tsuchikawa D, Shinntani N, Hashimoto H, Baba A, Koide R, Shioda S
- Journal Title
  
  J Mol Neurosci
  
  Volume: 43(1) Pages: 22-29
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592246
[Journal Article] Neuroprotective effect of PACAP against NMDA-induced retinal damage in the mouse2011
- Author(s)
  Endo K, Nakamachi T, Seki T, Kagami N, Wada Y, Nakamura K, Kishimoto K, Hori M, Tsuchikawa D, Shinntani N, Hashimoto H, Baba A, Koide R, Shioda S
- Journal Title
  
  J Mol Neurosci
  
  Volume: 43(1) Pages: 22-29
- Data Source
  KAKENHI-PROJECT-21592246
[Journal Article] Involvement of interleukin-1 in lipopolysaccaride-induced microglial activation and learning and memory deficits2011
- Author(s)
  Tanaka S, Kondo H, Kanda K, Ashino T, Nakamachi T, Sekikawa K, Iwakura Y, Shioda S, Numazawa S, Yoshida T
- Journal Title
  
  J Neurosci Res
  
  Volume: 89 Issue: 4 Pages: 506-514
- DOI
  10.1002/jnr.22582
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590143, KAKENHI-PROJECT-22791695
[Journal Article] Suppression of rat retinal ganglion cell death by PACAP following transient ischemia induced by high intraocular pressure2011
- Author(s)
  Seki T, Itoh H, Nakamachi T, Endo K, Wada Y, Nakamura K, Shioda S
- Journal Title
  
  J Mol Neurosci
  
  Volume: 43(1) Pages: 30-34
- Data Source
  KAKENHI-PROJECT-22791695
[Presentation] PACAP attenuates retinal damage in association with modulation of the microglia/macrophage status and cytokines expression2015
- Author(s)
  Nakamachi T, Wada Y, Endo K, Seki T, Shioda S.
- Organizer
  12th International Symposium in VIP, PACAP and Related Peptides.
- Place of Presentation
  Cappadokia, Turkey
- Year and Date
  2015-09-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24592681
[Presentation] Effects of PACAP on the secretions of tear and saliva in mouse.2015
- Author(s)
  Nakamachi T, Watanabe J, Seki T, Ohtaki H, Shioda S.
- Organizer
  Neuropeptides 2015.
- Place of Presentation
  Aberdeen, UK
- Year and Date
  2015-09-28
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24592681
[Presentation] Involvment of PACAP in differentiation of neural progenitor cells via radial glia.2015
- Author(s)
  Watanabe J, Ohtaki H, Nakamachi T, Sasaki S, Matsumoto M, Murai N, Seki T, Arata S, Shioda S.
- Organizer
  12th International Symposium in VIP, PACAP and Related Peptides.
- Place of Presentation
  Cappadokia, Turkey
- Year and Date
  2015-09-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24592681
[Presentation] マウスの涙液分泌調節機構におけるPACAPの役割2014
- Author(s)
  中町智哉，大滝博和，渡邊潤，関保，塩田清二
- Organizer
  日本動物学会　第85回仙台大会
- Place of Presentation
  仙台
- Year and Date
  2014-09-13
- Data Source
  KAKENHI-PROJECT-24592680
[Presentation] PACAP stimulates tear secretion through AQP5 signal in mouse.2014
- Author(s)
  Tomoya Nakamachi, Hirokazu Ohtaki, Jun Watanabe, Tamotsu Seki, Seiji Shioda
- Organizer
  20th International Symposium on Regulatory Peptides (Regpep2014)
- Place of Presentation
  京都
- Year and Date
  2014-09-09
- Data Source
  KAKENHI-PROJECT-24592680
[Presentation] 緑内障モデルマウスを用いたPACAPのロ網膜保護機構の検討～マイクグリア/マクロファージの関与～2013
- Author(s)
  中町智哉, 和田悦洋, 関保, 加賀美信幸, 今井ノリ, 荒田悟, 塩田清二
- Organizer
  第60回日本実験動物学会総会
- Place of Presentation
  筑波
- Data Source
  KAKENHI-PROJECT-24592680
[Presentation] マウスにおけるPACAPの角膜傷害治癒効果の検討2013
- Author(s)
  中町智哉、Forkas Jozsef, 和田悦洋、関保、Matkovits Attila、加賀美信幸、土田将史、吉川輝、杉山　公一、今井ノリ、荒田悟、塩田清二
- Organizer
  第118回日本解剖学会総会・全国学術集会
- Place of Presentation
  香川, サンポートホール高松
- Data Source
  KAKENHI-PROJECT-24592680
[Presentation] マウス硝子体内へのPACAP投与による網膜保護効果と局所免疫環境変化についての検討2013
- Author(s)
  中町智哉, 和田悦洋, 関保, 堀元英, 吉川輝, 土田将史, 杉山公一, 加賀美信幸, 今井ノリ, 荒田悟, 塩田清二
- Organizer
  第38回日本比較内分泌学会大会・第40回日本神経内分泌学会学術集会合同大会
- Place of Presentation
  宮崎
- Data Source
  KAKENHI-PROJECT-24592680
[Presentation] Expression and localization of IL-6 and PACAP receptor in mouse brain after global ischemia.2013
- Author(s)
  Nakamachi, T., Kagami, N., Hori, M., Yoshikawa, A., Sugiyama, K., Imai, N., Seki, T., Arata, S., Shioda, S.
- Organizer
  Neuroscience 2013, Society for Neuroscience's 43rd annual meeting.
- Place of Presentation
  San Diego, CA
- Data Source
  KAKENHI-PROJECT-24592680
[Presentation] マウスにおけるPACAPの角膜傷害治癒効果の検討2013
- Author(s)
  中町智哉、Forkas Jozsef, 和田悦洋、関保、Matkovits Attila、加賀美信幸、土田将史、吉川輝、杉山　公一、今井ノリ、荒田悟、塩田清二
- Organizer
  第118回日本解剖学会総会・全国学術集会
- Place of Presentation
  香川, サンポートホール高松
- Data Source
  KAKENHI-PROJECT-24592681
[Presentation] Expression and localization of IL-6 and PACAP receptor in mouse brain after global ischemia2013
- Author(s)
  Nakamachi T, Kagami N, Hori M, Yoshikawa A, Sugiyama K, Imai N, Seki T, Arata S, Shioda S
- Organizer
  Society for Neuroscience's 43rd annual meeting
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-24592681
[Presentation] 緑内障モデルマウスを用いたPACAPの網膜保護機構の検討～マイクログリア/マクロファージの関与～2013
- Author(s)
  中町智哉、和田悦洋、関保、加賀美信幸、今井ノリ、荒田悟、塩田清二
- Organizer
  第60回日本実験動物学会総会
- Place of Presentation
  つくば市、茨木
- Data Source
  KAKENHI-PROJECT-24592681
[Presentation] 神経ペプチドPACAPの網膜保護効果における網膜局所免疫環境の変化についての検討－網膜保護効果へのマイクログリア／マクロファージとTGF-βの寄与－2012
- Author(s)
  中町智哉・和田悦洋・遠藤貴美・中村圭輔・堀元英・土川大介・吉川輝・土田将史・加賀美信幸・今井ノリ・関保・小出良平・塩田清二
- Organizer
  第9回GPCR研究会
- Place of Presentation
  東京,科学未来館
- Data Source
  KAKENHI-PROJECT-24592681
[Presentation] PACAP stimulates tear secretion in mouse2012
- Author(s)
  T. Nakamachi, Y. Aizawa, H. Ohtaki, S. Yofu, Y. Wada, T. Seki, S. Arata, N. Shintani, H. Hashimoto, A. Baba and Seiji Shioda
- Organizer
  19th International Symposium on Regulatory Peptides
- Place of Presentation
  Copenhagen, Denmark
- Data Source
  KAKENHI-PROJECT-24592681
[Presentation] PACAP誘導性の涙液分泌におけるアクアポリン5の役割2012
- Author(s)
  中町智哉、会沢洋一、大滝博和、養父佐知子、関保、和田悦洋、荒田悟、新谷紀人、橋本均、馬場明道、塩田清二
- Organizer
  第117回日本解剖学会総会・全国学術集会
- Place of Presentation
  甲府
- Data Source
  KAKENHI-PROJECT-21592246
[Presentation] PACAP stimulates tear secretion in mouse2012
- Author(s)
  T. Nakamachi, Y. Aizawa, H. Ohtaki, S. Yofu, Y. Wada, T. Seki, S. Arata, N. Shintani, H. Hashimoto, A. Baba and Seiji Shioda
- Organizer
  19th International Symposium on Regulatory Peptides
- Place of Presentation
  Copenhagen, Denmark
- Data Source
  KAKENHI-PROJECT-24592680
[Presentation] 神経ペプチドPACAPの網膜保護効果における網膜局所免疫環境の変化についての検討－網膜保護効果へのマイクログリア／マクロファージとTGF-βの寄与－2012
- Author(s)
  中町智哉・和田悦洋・遠藤貴美・中村圭輔・堀元英・土川大介・吉川輝・土田将史・加賀美信幸・今井ノリ・関保・小出良平・塩田清二
- Organizer
  第9回GPCR研究会
- Place of Presentation
  東京,　科学未来館
- Data Source
  KAKENHI-PROJECT-24592680
[Presentation] PACAP誘導性の涙液分泌におけるアクアポリン5の役割2012
- Author(s)
  中町智哉、会沢洋一、大滝博和、養父佐知子、関保、和田悦洋、荒田悟、新谷紀人、橋本均、馬場明道、塩田清二
- Organizer
  第117回日本解剖学会総会・全国学術集会
- Place of Presentation
  甲府
- Data Source
  KAKENHI-PROJECT-22791695
[Presentation] PACAP suppresses retinal neuronal damage through modulation of the activation state of retinal microglia/macrophage2012
- Author(s)
  Nakamachi T, Wada Y, Seki T, Tsuchikawa D, Hori M, Tsuchida M, Yoshikawa A, Matkovits A, Kagami N, Imai N, Arata S and Shioda S
- Organizer
  The 42th Annual Meeting of the Society for Neuroscience
- Place of Presentation
  New Orleasns, LA
- Data Source
  KAKENHI-PROJECT-24592681
[Presentation] PACAP suppresses retinal neuronal damage through modulation of the activation state of retinal microglia/macrophage2012
- Author(s)
  Nakamachi T, Wada Y, Seki T, Tsuchikawa D, Hori M, Tsuchida M, Yoshikawa A, Matkovits A, Kagami N, Imai N, Arata S and Shioda S
- Organizer
  The 42th Annual Meeting of the Society for Neuroscience
- Place of Presentation
  New Orleasns, LA
- Data Source
  KAKENHI-PROJECT-24592680
[Presentation] Investigation Of Neuroprotective Effects Of PACAP Against NMDA-induced Retinal Damage in Mice2011
- Author(s)
  Seki T, Nakamachi T, Endo K, Shioda S
- Organizer
  ARVO (The Association for Research in Vision and Ophthalmology)
- Place of Presentation
  Fortlauderdale, Fl
- Data Source
  KAKENHI-PROJECT-21592246
[Presentation] The exogenous PACAP is possible modulater of the activation of retinal microglia/macrophage in the injury retina2011
- Author(s)
  Wada Y, Nakamachi T, Endo K, Seki T, Ohtaki H, Tsuchikawa D, Hori M, Farkas J, Tsuchida M, Yoshikawa A, Kagami N, Imai N, Shioda S
- Organizer
  Symposium of the 20th Annual Meeting of The Israel Society for Neuroscience "Basic and Clinical Research of GPCRs"
- Place of Presentation
  Eilat, Israel
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PROJECT-21592246
[Presentation] PACAP STIMULATES THE LACRIMATION VIA AQUAPORIN 5 TRANSLOCATOIN IN MOUSE2011
- Author(s)
  Nakamachi T, Aizawa Y, Ohtaki H, Seki T, Wada Y, Kagami N, Arata S, Hashimoto H, Shintani N, Baba A, Farkas J, Reglodi D and Shioda S
- Organizer
  The 10th international Symposium on VIP, PACAP and Related Peptides
- Place of Presentation
  Eilat, Israel
- Data Source
  KAKENHI-PROJECT-22791695
[Presentation] The exogenous PACAP is possible modulater of the activation of retinal microglia/macrophage in the injury retina2011
- Author(s)
  Wada Y, Nakamachi T, Endo K, Seki T, Ohtaki H, Tsuchikawa D, Hori M, Farkas J, Tsuchida M, Yoshikawa A, Kagami N, Imai N, Shioda S
- Organizer
  Symposium of the 20th Annual Meeting of The Israel Society for Neuroscience~Basic and Clinical Research of GPCRs~
- Place of Presentation
  Eilat, Israel
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PROJECT-22791695
[Presentation] Effect of pituitary adenylate cyclase-activating polypeptide (PACAP) on reactive astrocyte induced by brain damage in mice2011
- Author(s)
  Nakamachi T, Nakamura K, Wada Y, Kagami N, Tsuchikawa D, Hori M, Imai N, Yoshikawa A, Seki T, Atrata S, Shioda S
- Organizer
  41st Annual meeting Society for Neuroscience
- Place of Presentation
  Washington DC, USA
- Year and Date
  2011-11-15
- Data Source
  KAKENHI-PROJECT-21592246
[Presentation] Effect of pituitary adenylate cyclase-activating polypeptide(PACAP) on reactive astrocyte induced by brain damage in mice2011
- Author(s)
  Tomoya Nakamachi, Keisuke Nakamura, Yoshihiro Wada, Nobuyuki Kagami, Daisuke Tsuchikawa, Motohide Hori, Nori Imai, Akira Yoshikawa, Tamotsu Seki, Satoru Arata, and Seiji Shioda
- Organizer
  The 41th Annual Meeting of the Society for Neuroscience
- Place of Presentation
  Washington, DC
- Data Source
  KAKENHI-PROJECT-21592246
[Presentation] The retinoprotective effect of exogenous PACAP involves a modulation of retinal microglia/macrophage2011
- Author(s)
  Wada Y, Nakamachi T, Endo K, Seki T, Ohtaki H, Tsuchikawa D, Hori M, Farkas J, Tsuchida M, Yoshikawa A, Kagami N, Imai N, Shioda S
- Organizer
  The 10th international Symposium on VIP, PACAP and Related Peptides
- Place of Presentation
  Eilat, Israel
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-21592246
[Presentation] PACAPによる涙液分泌促進作用機序の解析2011
- Author(s)
  中町智哉・会沢洋一・大滝博和・関保・和田悦洋・加賀美信幸・荒田悟・塩田清二
- Organizer
  第36回日本比較内分泌学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21592246
[Presentation] PACAP stimulates the lacrimation via aquaporin 5 translocatoin in mouse2011
- Author(s)
  Nakamchi T, Aizawa Y, Ohtaki H, Seki T, Wada Y, Kagami N, Arata S, Hashimoto H, Shintani N, Baba A, Farkas J, Reglodi D, Shioda S
- Organizer
  The 10th internatlonal Symposium on VIP, PACAP and Related Peptides
- Place of Presentation
  Eilat, Israel
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22791695
[Presentation] Investigation Of Neuroprotective Effects Of PACAP Against NMDA-induced Retinal Damage in Mice. ARVO2011
- Author(s)
  Seki T, Nakamachi T, Endo K, Shioda S
- Organizer
  The Association for Research in Vision and Ophthalmology
- Place of Presentation
  Fortlauderdale, Fl.
- Data Source
  KAKENHI-PROJECT-21592246
[Presentation] PACAP STIMULATES THE LACRIMATION VIA AQUAPORIN 5 TRANSLOCATOIN IN MOUSE2011
- Author(s)
  Nakamachi T, Aizawa Y, Ohtaki H, Seki T, Wada Y, Kagami N, Arata S, Hashimoto H, Shintani N, Baba A, Farkas J, Reglodi D and Shioda S
- Organizer
  The 10th international Symposium on VIP, PACAP and Related Peptides
- Place of Presentation
  Eilat, Israel
- Data Source
  KAKENHI-PROJECT-21592246
[Presentation] 涙液分泌機能低下を示すPACAP欠損マウスを用いた涙液分泌機構の解析2011
- Author(s)
  中町智哉、会沢洋一、大滝博和、関保、和田悦洋、加賀美信幸、荒田悟、塩田清二
- Organizer
  第58回日本実験動物学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21592246
[Presentation] 新規ドライアイ疾患モデル動物としてのPACAP遺伝子欠損マウスの評価2011
- Author(s)
  中町智哉、会沢洋一、大滝博和、関保、遠藤貴美、荒田悟、新谷紀人、橋本均、馬場明道、塩田清二
- Organizer
  第57回日本実験動物学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21592246
[Presentation] Effect of pituitary adenylate cyclase-activating polypeptide(PACAP) on reactive astrocyte induced by brain damage in mice2011
- Author(s)
  Tomoya Nakamachi, Keisuke Nakamura, Yoshihiro Wada, Nobuyuki Kagami, Daisuke Tsuchikawa, Motohide Hori, Nori Imai, Akira Yoshikawa, Tamotsu Seki, Satoru Arata, and Seiji Shioda
- Organizer
  The 41th Annual Meeting of the Society for Neuroscience
- Place of Presentation
  Washington, DC
- Data Source
  KAKENHI-PROJECT-22791695
[Presentation] Effect of pituitary adenylate cyclase-activating polypeptide (PACAP) on reactive astrocyte induced by brain damage in mice2011
- Author(s)
  Nakamachi T, Nakamura K, Wada Y, Kagami N, Tsuchikawa D, Hori M, Imai N, Yoshikawa A, Seki T, Atrata S, Shioda S
- Organizer
  41st Annual meeting Society for Neuroscience
- Place of Presentation
  Washington DC, USA
- Year and Date
  2011-11-15
- Data Source
  KAKENHI-PROJECT-22791695
[Presentation] The retinoprotective effect of exogenous PACAP involves a modulation of retinal microglia/macrophage2011
- Author(s)
  Wada Y, Nakamachi T, Endo K, Seki T, Ohtaki H, Tsuchikawa D, Hori M, Farkas J, Tsuchida M, Yoshikawa A, Kagami N, Imai N, Shioda S
- Organizer
  The 10th international Symposium on VIP, PACAP and Related Peptides
- Place of Presentation
  Eilat, Israel
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-22791695
[Presentation] PACAPによる涙液分泌促進作用機序の解析2011
- Author(s)
  中町智哉・会沢洋一・大滝博和・関保・和田悦洋・加賀美信幸・荒田悟・塩田清二
- Organizer
  第36回日本比較内分泌学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22791695
[Presentation] 涙液分泌機能低下を示すPACAP欠損マウスを用いた涙液分泌機構の解析2011
- Author(s)
  中町智哉、会沢洋一、大滝博和、関保、和田悦洋、加賀美信幸、荒田悟、塩田清二
- Organizer
  第58回日本実験動物学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22791695
[Presentation] Investigation Of Neuroprotective Effects Of PACAP Against NMDA-induced Retinal Damage in Mice2011
- Author(s)
  Seki T, Nakamachi T, Endo K, Shioda S
- Organizer
  ARVO(The Association for Research in Vision and Ophthalmology)
- Place of Presentation
  Fortlauderdale, Fl.
- Data Source
  KAKENHI-PROJECT-22791695
[Presentation] PACAP stimulates the lacrimation via aquaporin 5 translocatoin in mouse2011
- Author(s)
  Nakamachi T, Aizawa Y, Ohtaki H, Seki T, Wada Y, Kagami N, Arata S, Hashimoto H, Shintani N, Baba A, Farkas J, Reglodi D, Shioda S
- Organizer
  The 10th international Symposium on VIP, PACAP and Related Peptides
- Place of Presentation
  Eilat, Israel
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-21592246
[Presentation] PACAP遺伝子欠損マウスにおける涙液分泌機能異常2010
- Author(s)
  中町智哉・会沢洋一・大滝博和・養父佐知子・関保、遠藤貴美、荒田悟、新谷紀人、橋本均、馬場明道、塩田清二
- Organizer
  第115回日本解剖学会総会・全国学術集会
- Place of Presentation
  盛岡
- Data Source
  KAKENHI-PROJECT-21592246
[Presentation] Neuroprotective Effect of PACAP(Pituitary Adenylate Cyclase-Activating Polypeptide)against NMDA-induced retinal damage in mice2010
- Author(s)
  K.Endo, T.Nakamachi, T.Seki, N.Kagami, K.Nakamura, Y.Wada, K.Kishimoto, Y.Ichohashi, S.Shioda
- Organizer
  GPCR2010
- Place of Presentation
  京都ガーデンパレスホテル
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-21592246
[Presentation] Retinal Protective Effect of Pituitary Adenylate Cyclase-activating Polypeptide(PACAP) Against NMDA-induced Damage in Mice2010
- Author(s)
  Nakamachi T, Endo K, Seki T, Kagami N, Nakamura K, Wada Y, Kishimoto K, Farkas J, Arata S, Shioda S
- Organizer
  5th International Peptide Symposium
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-21592246
[Presentation] Neuroprotective effect of PACAP(Pituitary adenylate cyclase-activating polypeptide) against NMDA-induced retinal damage in mice2010
- Author(s)
  Endo K, Nakamachi T, Seki T, Kagami N, Nakamura K, Wada Y, Kishimoto K, Ichihashi Y, Shioda S
- Organizer
  Official satellite symposium of the 14th International Congress of Endocrinology(ICE2010)(GPCR2010)
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-21592246
[Presentation] Retinal Protective Effect of Pituitary Adenylate Cyclase-activating Polypeptide(PACAP)Against NMDA-induced Damage in Mice2010
- Author(s)
  Tomoya Nakamachi, Kimi Endo, Tamotsu Seki, Nobuyuki Kagami, Keisuke Nakamura, Yoshihiro Wada Kouji Kishimoto, Jozsef Farkas, Satoru Arata, Seiji Shioda
- Organizer
  5th International Peptide Symposium
- Place of Presentation
  京都
- Year and Date
  2010-12-05
- Data Source
  KAKENHI-PROJECT-21592246
[Presentation] Retinal Protective Effect of Pituitary Adenylate Cyclase-activating Polypeptide (PACAP) Against NMDA-induced Damage in Mice2010
- Author(s)
  Tomoya Nakamachi, Kimi Endo, Tamotsu Seki, Nobuyuki Kagami, Keisuke Nakamura, Yoshihiro Wada, Kouji Kishimoto, Jozsef Farkas, Satoru Arata, Seiji Shioda
- Organizer
  5th International Peptide Symposium
- Place of Presentation
  京都
- Year and Date
  2010-12-05
- Data Source
  KAKENHI-PROJECT-22791695
[Presentation] NMDA誘導性網膜障害マウスに対するPACAPの保護効果2010
- Author(s)
  遠藤貴美, 中町智哉, 関保, 加賀美信幸, 中村圭輔, 市橋陽子, 塩田清二
- Organizer
  第115回日本解剖学会総会・全国学術大会
- Place of Presentation
  岩手県民会館
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-21592246
[Presentation] Distribution of activity-dependent neuroprotective protein (ADNP) and PAC1 receptor in intact and ischemic mouse brain2010
- Author(s)
  Tomoya Nakamachi, Kimi Endo, Tamotsu Seki, Nobuyuki Kagami, Keisuke Nakamura, Yoshihiro Wada, Kouji Kishimoto, Jozsef Farkas, Satoru Arata, Seiji Shioda
- Organizer
  40th Annual Meeting of the Society for Neuroscience
- Place of Presentation
  サンディエゴ(USA)
- Year and Date
  2010-11-13
- Data Source
  KAKENHI-PROJECT-22791695
[Presentation] NMDA誘導性網膜障害マウスに対するPACAPの保護効果2010
- Author(s)
  遠藤貴美・中町智哉・関保・加賀美信幸・中村圭輔・市橋陽子・塩田清二
- Organizer
  第115回日本解剖学会総会・全国学術集会
- Place of Presentation
  盛岡
- Data Source
  KAKENHI-PROJECT-21592246
[Presentation] 新規ドライアイ疾患モデル動物としてのPACAP遺伝子欠損マウスの評価2010
- Author(s)
  中町智哉、会沢洋一、大滝博和、関保、遠藤貴美、荒田悟、新谷紀人、橋本均、馬場明道、塩田清二
- Organizer
  第57回日本実験動物学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22791695
[Presentation] Retinal Protective Effect of Pituitary Adenylate Cyclase-activating Polypeptide(PACAP) Against NMDA-induced Damage in Mice2010
- Author(s)
  Nakamachi T, Endo K, Seki T, Kagami N, Nakamura K, Wada Y, Kishimoto K, Farkas J, Arata S, Shioda S
- Organizer
  5th International Peptide Symposium(Kyoto
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-22791695
[Presentation] Effect of PACAP on tear secretion in mouse2009
- Author(s)
  Nakamachi T, Aizawa Y, Ohtaki H, Yofu S, Seki T, Endo K, Nakamura K, Kagami N, Arata S, Shintani N, Hashimoto H, Baba A, Shioda S
- Organizer
  The 9th International Symposium on VIP, PACAP and Related Peptides
- Place of Presentation
  Kagoshima
- Data Source
  KAKENHI-PROJECT-21592246
[Presentation] Effects of Pituitary Adenylate Cyclase-Activating Polypeptide(PACAP)on the Survival of Ganglion Cells in the Rat Retina after Intraocular Hypertension2009
- Author(s)
  H.Itoh, T.Seki, T.Nakamachi, K.Endo, S.Shioda
- Organizer
  Yakushima2009(Satelite Symposium on The 9th international Symposium on VIP, PACAP and Related Peptides)
- Place of Presentation
  Kagoshima, Japan
- Year and Date
  2009-10-07
- Data Source
  KAKENHI-PROJECT-21592246
[Presentation] Effects of pituitary adenylate cyclase-activating polypeptide(PACAP) on the survival of ganglion cells in the rat retina after intraocular hypertension2009
- Author(s)
  Itoh H, Seki T, Nakamachi T, Endo K, Shioda S
- Organizer
  Yakushima 2009(Satellite Symposium of the 9th International Symposium on VIP, PACAP and Related Peptides) Phylogenetic Aspects of Neuropeptides-from Invertebrates to Humans
- Place of Presentation
  Yakushima, Kagoshima
- Data Source
  KAKENHI-PROJECT-21592246
[Presentation] EFFECT OF PACAP ON TEAR SECRETION IN MOUSE2009
- Author(s)
  T.Nakamachi, Y.Aizawa, H.Ohtaki, S.Yotu, T.Seki, K.Endo, K.Nakamura, K.Nobuyuki, S.Arata, N.Shintani, H.Hashimoto, A.Baba, S.Shioda
- Organizer
  The 9th international Symposium on VIP, PACAP and Related Peptides
- Place of Presentation
  Kagoshima, Japan
- Year and Date
  2009-10-07
- Data Source
  KAKENHI-PROJECT-21592246
[Presentation] Role of PACAP for impairment of cornea epithelial wound healing
- Author(s)
  Tamotsu Seki, Tomoya Nakamachi, Jozsef Farkas, Jun Watanab, Sachiko Izumi, Seiji Shioda
- Organizer
  Anual European Association for Vision and Eye Research Congress
- Place of Presentation
  Nice, France
- Year and Date
  2014-10-01 – 2014-10-04
- Data Source
  KAKENHI-PROJECT-24592681

1. SHIODA Seiji (80102375)

# of Collaborated Projects: 5 results

# of Collaborated Products: 55 results
2. NAKAMACHI Tomoya (30433840)

# of Collaborated Projects: 4 results

# of Collaborated Products: 65 results
3. WATANABE Jun (50649069)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. 大滝博和

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
5. 沼澤聡

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Seki Tamotsu 關 保

SEKI Tamotsu 關 保

關 保 セキ タモツ

関 保 セキ タモツ

Research Projects

Research Products

Co-Researchers

Effect of PACAP for prevention/treatment of dry eye syndrome

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Neuroprotective effect of PACAP against retinal damage in Glaucoma via immunomodurationPrincipal Investigator

Principal Investigator

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Mechanism of PACAP-induced tear secretion

Principal Investigator

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Effect of PACAP on adult retinal stem cell and the regenerative potential.Principal Investigator

Principal Investigator

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Functional significance of tumor necrosis factor alpha in inducing retinal ganglion cell death by using gene targeting methodPrincipal Investigator

Principal Investigator

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Research Institution

[Book] PACAP and neural development. In: Pituitary Adenylate Cyclase Activating Polypeptide &#8211; PACAP, (Eds. Reglodi D and Tamas A)2016

Author(s)

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[Journal Article] Pituitary adenylate cyclase-activating polypeptide (PACAP) is involved in adult mouse hippocampal neurogenesis after stroke.2016

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[Journal Article] 精密かつ体に優しい画像診断装置OCT2013

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[Journal Article] 糖尿病網膜症について2013

Author(s)

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[Journal Article] PACAP Attenuates NMDA-Induced Retinal Damage in Association with Modulation of the Microglia/Macrophage Status into an Acquired Deactivation Subtype.2013

Author(s)

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DOI

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[Journal Article] 東京都大田区における緑内障検診について2013

Author(s)

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[Journal Article] Distribution and protective function of pituitary adenylate cyclase-activating polypeptide in the retina.2012

Author(s)

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DOI

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[Journal Article] 大田区における緑内障検診2012

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[Journal Article] Suppression of rat retinal ganglion cell death by PACAP following transient ischemia induced by high intraocular pressure.2011

Author(s)

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[Journal Article] Neuroprotective effect of PACAP against NMDA-induced retinal damage in the mouse2011

Author(s)

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Seki Tamotsu 關保

SEKI Tamotsu 關保

關保セキタモツ

関保セキタモツ

[Book] PACAP and neural development. In: Pituitary Adenylate Cyclase Activating Polypeptide – PACAP, (Eds. Reglodi D and Tamas A)2016