YAGIHASHI Norito 八木橋法登

Researcher Number	10250622
Affiliation (based on the past Project Information) *help	2003: 弘前大学, 医学部, 講師 1999 – 2000: 弘前大学, 医学部, 講師 1995 – 1998: 弘前大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Kidney internal medicine Except Principal Investigator Experimental pathology / Human pathology
Keywords	Principal Investigator 一酸化窒素 / GKラット / 一酸化窒素合成酵素 / 糖尿病性腎症 / トランスジェニックマウス / aldose reductase / 酸化ストレス / 免疫組織化学 / シクロオキシゲナーゼ Except Principal Investigator 合併症 … More / AGE / 糖尿病 / Neuropathy / 末梢神経障害 / ポリオール代謝 / アルドース還元酵素 / グリケーション / RAGE / Aldose reductase / Polyol pathway / 血管障害 / トランスジェニックマウス / 細胞傷害 / AGE(後期糖化生成物) / Diabetic complications / Target therapy / Glycation / ニューロパチー / 細胞傷害機構 / 遺伝子改変動物 / 標的治療 / Microangiopathy / Advanced glycation end-products / Complications / Tissue injury / Diabetes mellit / 酸化ストレス / 活性酸素 / 細小血管障害 / 細胞障害 / Inhibitor / Nephropathy / Transgenic Mice / Complication / Polyol Pathway / Aldose Reductase / Diabetes / 阻害剤 / 腎症 / アポトーシス / 神経変性 / 免疫組織化学 / アルツハイマー病 / 老化 / 組織分布 Less

Exploration of pathogenesis of diabetic complications using transgenic mice and attempts of gene therapy
- Principal Investigator
  
  YAGIHASHI Soroku
- Project Period (FY)
  2002 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Hirosaki University
糖尿病性びまん性糸球体病変形成に関わる一酸化窒素発現の役割Principal Investigator
- Principal Investigator
  
  八木橋法登
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Hirosaki University
後期糖化生成物およびその受容体の生体内分布と組織病変とのかかわりについて
- Principal Investigator
  
  YAGIHASHI Soroku
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Human pathology
- Research Institution
  Hirosaki University
Hyperglycemic tissue injury: Pathogenesis of diabetic complications and its prevention
- Principal Investigator
  
  YAGIHASHI Soroku
- Project Period (FY)
  1998 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Hirosaki University
初期糖尿病性腎症の病因の解析一酸化窒素との関連についてPrincipal Investigator
- Principal Investigator
  
  八木橋法登
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Hirosaki University
Fundamental studies on the pathogenesis of diabetic complications using transgenic mice expressing human aldose reductase
- Principal Investigator
  
  YAGIHASHI Soroku
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Hirosaki University

All 2006 2005 2004 2003

All Journal Article Book

[Book] 臨床医のための糖尿病病理2004
- Author(s)
  八木橋操六
- Total Pages
  241
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-14370073
[Journal Article] Prolonged ischemic conduction failure after reperfusion in diabetic nerve.2006
- Author(s)
  Baba M, Nukada H, McMorran D, Takahashi K, Wada R, Yagihashi S
- Journal Title
  
  Muscle Nerve 33
  
  Pages: 350-355
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370073
[Journal Article] Prolonged ischemic conduction failure after reperfusion in diabetic nerve.2006
- Author(s)
  Baba M, Nukdada H, McMorran D, Takahashi K, Wada R, Yagihashi S.
- Journal Title
  
  Muscle Nerve 33・3
  
  Pages: 350-355
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370073
[Journal Article] Role of advanced glycation endproducts and their receptors in development of diabetic neuropathy.2005
- Author(s)
  Wada R, Yagihashi S
- Journal Title
  
  Ann NY Acad Sci 1043
  
  Pages: 598-604
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370073
[Journal Article] Role of advanced glycation endproducts and their receptors in development of diabetic neuropathy.2005
- Author(s)
  Wada R, Yagihashi S.
- Journal Title
  
  Ann NY Acad Sci 1043
  
  Pages: 598-604
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370073
[Journal Article] Transgenic expression of BACH1 transcription factor results in megakaryocytic impairment.2005
- Author(s)
  Toki T, Yagihashi S, et al.
- Journal Title
  
  Blood 105(8)
  
  Pages: 3100-3108
- Data Source
  KAKENHI-PROJECT-14370073
[Journal Article] Prolonged ischemic conduction failure after reperfusion in diabetic nerve.2005
- Author(s)
  Baba M, Yagihashi S, et al.
- Journal Title
  
  Muscle Nerve 33(3)
  
  Pages: 350-355
- Data Source
  KAKENHI-PROJECT-14370073
[Journal Article] Role of advanced glycation end products and their receptors in development of diabetic neuropathy.2005
- Author(s)
  Wada R, Yagihashi S.
- Journal Title
  
  Ann N Y Acad Sci 1043
  
  Pages: 598-604
- Data Source
  KAKENHI-PROJECT-14370073
[Journal Article] Effects of polyol pathway hyperactivity on protein kinase C activity, nociceptive peptide expression, and neuronal structure in dorsal root ganglia in diabetic mice.2004
- Author(s)
  Uehara K, Yamagishi S, Chin S, Yagihashi S.
- Journal Title
  
  Diabetes 53・12
  
  Pages: 3239-3247
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370073
[Journal Article] Reduced cell replication and induction of apoptosis by advanced glycation end products in rat Schwann cells.2004
- Author(s)
  Sekido H, Suzuki T, Jomori T, Takeuchi M, Yabe-Nishimura C, Yagihashi S
- Journal Title
  
  Biochem Biophys Res Commun 320
  
  Pages: 214-248
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370073
[Journal Article] Peripheral nerve endoneurial microangiopathy and necrosis in rats with insulinoma.2004
- Author(s)
  Sugimoto K, Shoji M, Yasujima M, Suda T, Yagihashi S
- Journal Title
  
  Acta Neuropathol (Berl) 108
  
  Pages: 503-514
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370073
[Journal Article] Peripheral nerve endoneurial microangiopathy and necrosis in rats with insulinoma.2004
- Author(s)
  Sugimoto K, Shoji M, Yasujima M, Suda T, Yagihashi S.
- Journal Title
  
  Acta Neuropathol 108・6(Berl)
  
  Pages: 503-514
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370073
[Journal Article] Effects of polyol pathway hyperactivity on protein kinase C activity, nociceptive peptide expression, and neuronal structure in dorsal root ganglia in diabetic mice.2004
- Author(s)
  Uehara K, Yamagishi S, Otsuki S, Chin S, Yagihashi S
- Journal Title
  
  Diabetes 53
  
  Pages: 3239-3247
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370073
[Journal Article] Reduced cell replication and induction of apoptosis by advanced glycation end products in rat Schwann cells.2004
- Author(s)
  Sekido H, Suzuki T, Jomori T, Takeuchi M, Yabe-Nishimura C, Yagihashi S.
- Journal Title
  
  Biochem Biophys Res Commun 320・1
  
  Pages: 214-248
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370073
[Journal Article] Differential influence of increased polyol pathway on protein kinase C expressions between endoneurial and epineurial tissues in diabetic mice.2003
- Author(s)
  Yamagishi S, Uehara K, Otsuki S, Yagihashi S:
- Journal Title
  
  J Neurochem 87
  
  Pages: 497-507
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370073
[Journal Article] Differential influence of increased polyol pathway on protein kinase C expressions between endoneurial and epineurial tissues in diabetic mice.2003
- Author(s)
  Yamagishi S, Uehara K, Otsuki S, Yagihashi S.
- Journal Title
  
  J Neurochem 87・2
  
  Pages: 497-507
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370073

1. YAGIHASHI Soroku (40111231)

# of Collaborated Projects: 4 results

# of Collaborated Products: 16 results
2. KUROTAKI Hidekachi (40215108)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. WADA Ryuichi (20260408)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
4. YAMAGISHI Shinichiro (80301026)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
5. BABA Masayuki (90106849)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
6. MIZUKAMI Hiroki (00374819)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

YAGIHASHI Norito 八木橋 法登

Research Projects

Research Products

Co-Researchers

Exploration of pathogenesis of diabetic complications using transgenic mice and attempts of gene therapy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

糖尿病性びまん性糸球体病変形成に関わる一酸化窒素発現の役割Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

後期糖化生成物およびその受容体の生体内分布と組織病変とのかかわりについて

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Hyperglycemic tissue injury: Pathogenesis of diabetic complications and its prevention

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

初期糖尿病性腎症の病因の解析 一酸化窒素との関連についてPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Fundamental studies on the pathogenesis of diabetic complications using transgenic mice expressing human aldose reductase

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 臨床医のための糖尿病病理2004

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Prolonged ischemic conduction failure after reperfusion in diabetic nerve.2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Prolonged ischemic conduction failure after reperfusion in diabetic nerve.2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Role of advanced glycation endproducts and their receptors in development of diabetic neuropathy.2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Role of advanced glycation endproducts and their receptors in development of diabetic neuropathy.2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Transgenic expression of BACH1 transcription factor results in megakaryocytic impairment.2005

Author(s)

Journal Title

Data Source

[Journal Article] Prolonged ischemic conduction failure after reperfusion in diabetic nerve.2005

Author(s)

Journal Title

Data Source

[Journal Article] Role of advanced glycation end products and their receptors in development of diabetic neuropathy.2005

Author(s)

Journal Title

Data Source

[Journal Article] Effects of polyol pathway hyperactivity on protein kinase C activity, nociceptive peptide expression, and neuronal structure in dorsal root ganglia in diabetic mice.2004

Author(s)

Journal Title

YAGIHASHI Norito 八木橋法登

初期糖尿病性腎症の病因の解析一酸化窒素との関連についてPrincipal Investigator