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YAMAMOTO Tohru  山本 融

ORCIDConnect your ORCID iD *help
… Alternative Names

山本 融  ヤマモト トオル

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Researcher Number 10251480
Other IDs
External Links
Affiliation (Current) 2025: 香川大学, 医学部, 教授
Affiliation (based on the past Project Information) *help 2025: 香川大学, 医学部, 教授
2013 – 2023: 香川大学, 医学部, 教授
2012: 北海道大学, 薬学研究科(研究院), 准教授
2008 – 2012: Hokkaido University, 大学院・薬学研究院, 准教授
2003 – 2004: 独立行政法人理化学研究所, 非対称細胞分裂研究グループ, 研究員 … More
2001 – 2002: 東北大学, 加齢医学研究所, 助手
2001: 東北大学, 加齢医学・研究所, 助手
1994 – 1997: 東京大学, 分子細胞生物学研究所, 助手 Less
Review Section/Research Field
Principal Investigator
Biological Sciences / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Biological pharmacy / Molecular biology / Nerve anatomy/Neuropathology / Basic veterinary science/Basic zootechnical science
Except Principal Investigator
Cell biology / Biological pharmacy / Biological Sciences
Keywords
Principal Investigator
神経回路 / 神経発生 / TFIID / 新規因子 / 神経分化 / 運動神経 / two-hybrid法 / 転写因子 / 転写調節 / TATAボックス結合因子 … More / CCG1 / E/Iバランス / MDGA2 / MDGA1 / 統合失調症 / 軸索ガイダンス / クロマチン転写 / 自閉スペクトラム症 / ニューロリギン / E/Iバランス / シナプス形成 / Neuroligin / 自閉症スペクトラム障害 / 大脳皮質 / one-hybrid法 / NF-κB / Sp1 / Tat / HIV / Bromodomain / 細胞周期 / 軸索輸送 / 神経変性 / Alcadein / APP / 小胞輸送 / 精神神経疾患 / MDGA / 社会性行動 / 記憶 / ニューレキシン / 行動解析 / 自閉症 / 行動異常 / 自閉症スペクトラム / 組織構築 / 神経細胞 / 発生分化 / 細胞移動 / 脊髄小行路 / 神田回路綱形成 / 軸索伸長 / 伝導路 / 脊髄 / ニワトリ / 電気穿孔法 / 上行性伝導路 / 神経回路網形成 / 脊髄神経 / 脊髄小脳路 / 脊髄上行路 / ブロモドメイン / CCGl / two-bybrid法 / SW14 / ドメイン / 核 … More
Except Principal Investigator
MysPDZ(Myo18A) / 細胞間相互作用 / 造血幹細胞 / マイクロアレイ / 遺伝子発現プロファイル / 間質細胞 / 骨髄 / 造血微小環境 / two-hybrid法 / TFIID / 転写調節 / 転写基本因子 / 転写調節因子 / microarray / gene expression profiles / mesenchymal stem cell cell lines / hematopoietic-microenvironment / bone marrow / 間葉系幹細胞 / 間葉系肝細胞 / 間質細胞株 / two-hybrid system / co-factor / Transcriptional regulatory factor / Development of drugs / Interaction between transcription factors / Interaction between DNA and transcription factors / Transcription factor / Transcriptional regulation / CTD / TBP / TFIIB / TATAボックス結合因子 / コファクター / 医薬品開発 / 転写因子間相互作用 / DNA-転写因子相互作用 / 転写因子 / 新規ミオシン遺伝子 / 不死化細胞株 / 骨髄間質細胞 / STAT1 / STAT5 / 多能性造血幹細胞 / 共培養 / サイトカイン / 微小環境 / 可塑性 / 幹細胞 / sphingoshine-1 phosphate / tenascin-c / ephrinB2 / Myo18A / MysPDZ / 転写活性化 / 癌遺伝子 / 相互作用 Less
  • Research Projects

    (24 results)
  • Research Products

    (107 results)
  • Co-Researchers

    (20 People)
  •  シナプス形成抑制機構に依拠する精神神経疾患治療方策の探索Principal Investigator

    • Principal Investigator
      山本 融
    • Project Period (FY)
      2025 – 2029
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
    • Research Institution
      Kagawa University
  •  Functional Analyses of 'privileged' vesicular transport carried with AlcadeinPrincipal Investigator

    • Principal Investigator
      山本 融
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
    • Research Institution
      Kagawa University
  •  Exploration of novel excitatory/inhibitory balance control mechanisms in neural circuits for the treatment of neuropsychiatric disorders.Principal Investigator

    • Principal Investigator
      Yamamoto Tohru
    • Project Period (FY)
      2019 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
    • Research Institution
      Kagawa University
  •  Functional analysis of MDGA family proteins on regulation of synapse formation and social behavior.Principal Investigator

    • Principal Investigator
      Yamamoto Tohru
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kagawa University
  •  Functional analysis of MDGA family proteins on neural circuit formation of cerebral cortex.Principal Investigator

    • Principal Investigator
      Yamamoto Tohru
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kagawa University
  •  Functional analysis of MDGA family proteins on corticogenesis.Principal Investigator

    • Principal Investigator
      YAMAMOTO Tohru
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Hokkaido University
  •  Ascending spinal tract formation in developing chickPrincipal Investigator

    • Principal Investigator
      YAMAMOTO Tohru
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research a proposed research project)
    • Research Field
      Basic veterinary science/Basic zootechnical science
    • Research Institution
      Hokkaido University
  •  運動神経の特定機能単位選択的に働く新規遺伝子群の解析Principal Investigator

    • Principal Investigator
      山本 融
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The Institute of Physical and Chemical Research
  •  運動神経の特定機能単位選択的に働く新規遺伝子群の解析Principal Investigator

    • Principal Investigator
      山本 融
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The Institute of Physical and Chemical Research
  •  運動神経の特定機能単位選択的に働く新規遺伝子群の解析Principal Investigator

    • Principal Investigator
      山本 融
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  新規遺伝子群による運動神経回路網形成機構の解析Principal Investigator

    • Principal Investigator
      山本 融
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Nerve anatomy/Neuropathology
    • Research Institution
      The Institute of Physical and Chemical Research
      Tohoku University
  •  Studies on Cellular Regulation of Hematopoietic Microembironment

    • Principal Investigator
      OBINATA Masuo
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cell biology
    • Research Institution
      Tohoku University
  •  運動神経分化の過程で機能単位選択的に働く遺伝子群の探索と解析Principal Investigator

    • Principal Investigator
      山本 融
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  運動神経の軸索伸長経路の決定に関与する因子群の探索と解析Principal Investigator

    • Principal Investigator
      山本 融
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Nerve anatomy/Neuropathology
    • Research Institution
      Tohoku University
  •  造血微小環境による造血幹細胞の分化制御機構

    • Principal Investigator
      OBINATA Masuo
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  HIV転写調節因子と相互作用する新規因子群の解析Principal Investigator

    • Principal Investigator
      山本 融
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  HIV転写調節因子と相互作用する新規因子群の検索Principal Investigator

    • Principal Investigator
      山本 融
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  ブロモドメインと相互作用する新規グローバル転写活性化因子の解析Principal Investigator

    • Principal Investigator
      山本 融
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Molecular biology
    • Research Institution
      The University of Tokyo
  •  転写調節機構の解析-調節因子と基本因子との相互作用を中心とした解析-

    • Principal Investigator
      堀越 正美
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  細胞周期因子CCG1と相互作用する因子の機能解析Principal Investigator

    • Principal Investigator
      山本 融
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  TFIID内Bromodomainの相互作用因子の機能解析Principal Investigator

    • Principal Investigator
      山本 融
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Molecular biology
    • Research Institution
      The University of Tokyo
  •  細胞周期因子CCG1の転写因子TEIIDサブユニットとしての役割Principal Investigator

    • Principal Investigator
      山本 融
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  TFIID内Bromodomainの機能解析と相互作用因子の探索Principal Investigator

    • Principal Investigator
      山本 融
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Molecular biology
    • Research Institution
      The University of Tokyo
  •  Basic research for development of new type of drugs based on the mechanism of transcriptional regulation

    • Principal Investigator
      HORIKOSHI Masami
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      The University of Tokyo

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 Other

All Journal Article Presentation Patent Other

  • [Journal Article] Early postnatal development of the MDGA2+/- mouse model of synaptic dysfunction2023

    • Author(s)
      Fertan Emre、Wong Aimee A.、Montbrun Thalia S. Garvock-de、Purdon Michaela K.、Roddick Kyle M.、Yamamoto Tohru、Brown Richard E.
    • Journal Title

      Behavioural Brain Research

      Volume: 452 Pages: 114590-114590

    • DOI

      10.1016/j.bbr.2023.114590

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K06597, KAKENHI-PROJECT-19K07065
  • [Journal Article] Brain <scp>p3‐Alcβ</scp> peptide restores neuronal viability impaired by Alzheimer's amyloid β‐peptide2023

    • Author(s)
      Hata S, Saito H, Kakiuchi T, Fukumoto D, Yamamoto S, Kasuga K, Kimura A, Moteki K, Abe R, Adachi S, Kinoshita S, Yoshizawa-Kumagaye K, Nishio H, Saito T, Saido TC, Yamamoto T, Nishimura M, Taru H, Sobu Y, Ohba H, Nishiyama S, Harada N, Ikeuchi T, Tsukada H, Ouchi Y, Suzuki T
    • Journal Title

      EMBO Molecular Medicine

      Volume: - Issue: 5 Pages: 1-15

    • DOI

      10.15252/emmm.202217052

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21KK0143, KAKENHI-PROJECT-19H03546, KAKENHI-PROJECT-20H03600, KAKENHI-PROJECT-22K06597, KAKENHI-PROJECT-23K06840, KAKENHI-PROJECT-19K07065, KAKENHI-PROJECT-22K15270, KAKENHI-PROJECT-23K26790
  • [Journal Article] Axonal transport of Frizzled5 by Alcadein α-containing vesicles is associated with kinesin-12023

    • Author(s)
      Shiraki Yuzuha、Mitsuma Monet、Takada Ritsuko、Hata Saori、Kitamura Akira、Takada Shinji、Kinjo Masataka、Taru Hidenori、M?ller Ulrike C.、Yamamoto Tohru、Sobu Yuriko、Suzuki Toshiharu
    • Journal Title

      Molecular Biology of the Cell

      Volume: 34 Issue: 11

    • DOI

      10.1091/mbc.e22-10-0495

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K06597, KAKENHI-PROJECT-23K06840, KAKENHI-PROJECT-19K07065, KAKENHI-PROJECT-22K15270, KAKENHI-PUBLICLY-22H05642, KAKENHI-PUBLICLY-22H04826, KAKENHI-PROJECT-22H04926, KAKENHI-PROJECT-21H02498
  • [Journal Article] Formation of N-acyl-phosphatidylethanolamines by cytosolic phospholipase A 2 ε in an ex vivo murine model of brain ischemia.2022

    • Author(s)
      Rahman SMK, Hussain Z, Morito K, Takahashi N, Sikder MM, Tanaka T, Ohta KI, Ueno M, Takahashi H, Yamamoto T, Murakami M, Uyama T, Ueda N.
    • Journal Title

      Biochim. Biophys. Acta Mol. Cell Biol. Lipds

      Volume: 1867 Issue: 12 Pages: 159222-159222

    • DOI

      10.1016/j.bbalip.2022.159222

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07065, KAKENHI-PROJECT-22K06597, KAKENHI-PROJECT-22K06885, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-20H05691
  • [Journal Article] Ascending spinal tract formation in chick embryo originating from different spinal regions2021

    • Author(s)
      Kokudo Y、Arakawa T、Takahashi H、Kobara H、Kamada M、Deguchi Ki、Touge T、Masaki T、Yamamoto T
    • Journal Title

      Brain Research

      Volume: 1768 Pages: 147595-147595

    • DOI

      10.1016/j.brainres.2021.147595

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07065
  • [Journal Article] Ras-like Gem GTPase induced by Npas4 promotes activity-dependent neuronal tolerance for ischemic stroke2021

    • Author(s)
      Takahashi Hiroo、Asahina Ryo、Fujioka Masayuki、Matsui Takeshi K.、Kato Shigeki、Mori Eiichiro、Hioki Hiroyuki、Yamamoto Tohru、Kobayashi Kazuto、Tsuboi Akio
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 118 Issue: 32 Pages: 66-72

    • DOI

      10.1073/pnas.2018850118

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K21664, KAKENHI-PROJECT-20H03199, KAKENHI-PROJECT-19K07065, KAKENHI-PROJECT-19K22687, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-23K21351
  • [Journal Article] Amyloidogenic processing of amyloid β protein precursor (APP) is enhanced in the brains of alcadein α-deficient mice2020

    • Author(s)
      Gotoh N、Saito Yi、Hata S、Saito H、Ojima D、Murayama Ci、Shigeta M、Abe T、Konno D、Matsuzaki F、Suzuki T、Yamamoto T
    • Journal Title

      Journal of Biological Chemistry

      Volume: 295 Issue: 28 Pages: 9650-9662

    • DOI

      10.1074/jbc.ra119.012386

    • NAID

      120007116485

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07065, KAKENHI-PUBLICLY-19H04791, KAKENHI-PROJECT-18H02566, KAKENHI-PROJECT-18K07384, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-18H04003
  • [Journal Article] Retinal ganglion cell loss in kinesin-1 cargo Alcadein α deficient mice.2020

    • Author(s)
      Nakano Y, Hirooka K, Chiba Y, Ueno M, Ojima D, Hossain MR, Takahashi H, Yamamoto T, Kiuchi Y.
    • Journal Title

      Cell Death Dis.

      Volume: 11 Issue: 3 Pages: 166-166

    • DOI

      10.1038/s41419-020-2363-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07065, KAKENHI-PROJECT-19K07508, KAKENHI-PROJECT-16K08237, KAKENHI-PROJECT-16H06276
  • [Journal Article] Decrease in p3‐Alcβ37 and p3‐Alcβ40, products of Alcadein β generated by γ‐secretase cleavages, in aged monkeys and patients with Alzheimer's disease2019

    • Author(s)
      Hata S、Omori C、Kimura A、Saito H、Kimura N、Gupta V、Pedrini S、Hone E、Chatterjee P、Taddei K、Kasuga K、Ikeuchi T、Waragai M、Nishimura M、Hu A、Nakaya T、Meijer L、Maeda M、Yamamoto T、Masters CL、Rowe CC、Ames D、Yamamoto K、Martins RN、Gandy S、Suzuki T
    • Journal Title

      Alzheimer's & Dementia: Translational Research & Clinical Interventions

      Volume: 5 Issue: 1 Pages: 740-750

    • DOI

      10.1016/j.trci.2019.09.015

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07384, KAKENHI-PROJECT-19K07065, KAKENHI-PROJECT-19K21585, KAKENHI-PUBLICLY-18H04851, KAKENHI-PROJECT-17H03574, KAKENHI-PROJECT-19H03546, KAKENHI-PROJECT-16K08237, KAKENHI-PROJECT-18H02566
  • [Journal Article] d-Allose Attenuates Overexpression of Inflammatory Cytokines after Cerebral Ischemia/Reperfusion Injury in Gerbil.2016

    • Author(s)
      Shinohara N, Nakamura T, Abe Y, Hifumi T, Kawakita K, Shinomiya A, Tamiya T, Tokuda M, Keep RF, Yamamoto T, Kuroda Y.
    • Journal Title

      J Stroke Cerebrovasc Dis.

      Volume: 25 Issue: 9 Pages: 2184-2188

    • DOI

      10.1016/j.jstrokecerebrovasdis.2016.01.030

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26293324, KAKENHI-PROJECT-26460123, KAKENHI-PROJECT-16K08237, KAKENHI-PROJECT-16K08497
  • [Journal Article] Ryanodine receptors contribute to the induction of ischemic tolerance.2016

    • Author(s)
      Nakamura-Maruyama E, Miyamoto O, Okabe N, Himi N, Feng L, Narita K, Keep RF, Yamamoto T, Nakamura T
    • Journal Title

      Brain Research Bulletin

      Volume: 122 Pages: 45-53

    • DOI

      10.1016/j.brainresbull.2016.02.018

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09846, KAKENHI-PROJECT-25460059, KAKENHI-PROJECT-15K16382, KAKENHI-PROJECT-16K08237
  • [Journal Article] Altered cortical dynamics and cognitive function upon haploinsufficiency of the autism-linked excitatory synaptic suppressor MDGA22016

    • Author(s)
      S. A. Connor, I. Ammendrup-Johnsen, A. W. Chan, Y. Kishimoto, C. Murayama, N. Kurihara, A. Tada, Y. Ge, H. Lu, R. Yan, J. M. LeDue, H. Matsumoto, H. Kiyonari, Y. Kirino, F. Matsuzaki, T. Suzuki, T. H. Murphy, Y. T. Wang, T. Yamamoto, A. M. Craig
    • Journal Title

      Neuron

      Volume: 91 Issue: 5 Pages: 1052-1068

    • DOI

      10.1016/j.neuron.2016.08.016

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K07910, KAKENHI-PROJECT-16K08237, KAKENHI-PROJECT-26293010, KAKENHI-PROJECT-16K14690
  • [Journal Article] Cytoplasmic Fragment of Alcadein α Generated by Regulated Intramembrane Proteolysis Enhances Amyloid β-Protein Precursor (APP) Transport into the Late Secretory Pathway and Facilitates APP Cleavage2015

    • Author(s)
      Norio Takei, Yuriko Sobu, Ayano Kimura, Satomi Urano, Yi Piao, Yoichi Araki, Hidenori Taru, Tohru Yamamoto, Saori Hata, Tadashi Nakaya, Toshiharu Suzuki
    • Journal Title

      Journal of Biological Chemistry

      Volume: 290 Issue: 2 Pages: 987-995

    • DOI

      10.1074/jbc.m114.599852

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25460058, KAKENHI-PROJECT-26293010, KAKENHI-PROJECT-26870464, KAKENHI-PROJECT-15K18854, KAKENHI-PROJECT-25460059
  • [Journal Article] Quantitative analysis of APP axonal transport in neurons: role of JIP1 in enhanced APP anterograde transport.2014

    • Author(s)
      Chiba K, Araseki M, Nozawa K, Furukori K, Araki Y, Matsushima T, Nakaya T,Hata S, Saito Y, Uchida S, Okada Y, Nairn AC, Davis RJ, Yamamoto T, Kinjo M, Taru, H, Suzuki T.
    • Journal Title

      Mol Biol Cell

      Volume: 25 Issue: 22 Pages: 3569-3580

    • DOI

      10.1091/mbc.e14-06-1111

    • NAID

      120005522339

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-25113723, KAKENHI-PROJECT-25293046, KAKENHI-PROJECT-25460058, KAKENHI-PROJECT-25460059, KAKENHI-PUBLICLY-26115721, KAKENHI-PROJECT-26293010
  • [Journal Article] Increased levels of plasma p3-Alcα35, a major fragment of Alcadeinα by γ-secretase cleavage, in Alzheimer's disease2014

    • Author(s)
      Omori C, Kaneko M, Nakajima E, Akatsu H, Waragai M, Maeda M, Moroshima-Kawashima M, Saito Y, Nakaya T, Taru H, Yamamoto T, Asada T, Hata S, Suzuki T. for J-ADNI
    • Journal Title

      J. Alzheimers Dis

      Volume: 39 Issue: 4 Pages: 861-870

    • DOI

      10.3233/jad-131610

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390017, KAKENHI-PROJECT-24500431, KAKENHI-PROJECT-24500433, KAKENHI-PROJECT-24591695, KAKENHI-PROJECT-24790062, KAKENHI-PROJECT-25460058, KAKENHI-PROJECT-25460059, KAKENHI-PROJECT-26293010
  • [Journal Article] Mechanism of Intracellular Cleavage of Alcadeins by γ-Secretases2013

    • Author(s)
      Piao Y, Kimura A, Urano S, Saito Y, Taru H, Yamamoto T, Hata S, Suzuki T
    • Journal Title

      PLoS One

      Volume: 8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590055
  • [Journal Article] Constitutive cleavage of the single-pass transmembrane protein Alcadein α prevents aberrant peripheral retention of Kinesin-12012

    • Author(s)
      Maruta C, Saito Y, Hata S, Gotoh N, Suzuki T, Yamamoto T
    • Journal Title

      PLoS One

      Volume: 7

    • NAID

      120004689031

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590055
  • [Journal Article] Membrane-microdomainlocalization of amyloid β -precursor protein (APP) C-terminal fragments is regulated by phosphorylation of the cytoplasmic Thr668 residue2012

    • Author(s)
      Matsushima T, Saito Y, Elliott JI, Iijima-Ando K, Nishimura M, Kimura N, Hata S, Yamamoto T, Nakaya T, Suzuki T
    • Journal Title

      J. Biol. Chem

      Volume: 287 Pages: 19715-19724

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590055
  • [Journal Article] A small peptide sequence is sufficient for nitiating kinesin-1 activation through part of TPR region of KLC12012

    • Author(s)
      Kawano T, Araseki M, Araki Y, Kinjo M, Yamamoto T, Suzuki T
    • Journal Title

      Traffic

      Volume: 13 Pages: 834-848

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590055
  • [Journal Article] IgSF molecule M DGA1 is involved in radial migration and positioning of a subset of cortical upper layer neurons.2011

    • Author(s)
      Ishikawa T, Gotoh N, Murayama C, Abe T, Iwashita M, Matsuzaki F, Suzuki T, Yamamoto T.
    • Journal Title

      Dev. Dyn. 240

      Pages: 96-107

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20200011
  • [Journal Article] Intracellular trafficking of the amyloid β-protein precursor(APP)regulated by novel function of X11-like2011

    • Author(s)
      Saito Y, Akiyama M, Araki Y, Sumioka A, Shiono M, Taru H, Nakaya T, Yamamoto T, Suzuki T
    • Journal Title

      PLoS One

      Volume: 6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590055
  • [Journal Article] Expression of sorting nexin 18 (SNX18) is dynamically regulated in developing spinal motor neurons2011

    • Author(s)
      Nakazawa S, Gotoh N, Matsumoto H, Murayama C, Suzuki T, Yamamoto T
    • Journal Title

      J. Histochem. Cytochem

      Volume: 59 Pages: 202-213

    • NAID

      120005906550

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590055
  • [Journal Article] Expression of sorting nexin 18 (SNX18) is dynamically regulated in developing spinal motor neurons.2011

    • Author(s)
      Nakazawa S, Gotoh N, Matsumoto H, Murayama C, Suzuki T, Yamamoto T.
    • Journal Title

      J. Histochem. Cytochem. 59

      Pages: 202-213

    • NAID

      120005906550

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20200011
  • [Journal Article] IgSF molecule MDGA1 is involved in radial migration and positioning of a subset of cortical upper layer neurons2011

    • Author(s)
      Ishikawa T, Gotoh N, Murayama C, Abe T, Iwashita M, Matsuzaki F, Suzuki T, Yamamoto T
    • Journal Title

      Dev. Dyn

      Volume: 240 Pages: 96-107

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590055
  • [Journal Article] Coordinated increase of γ-secretase reaction products in the plasma of some female Japanese sporadic Alzheimer's disease patients: quantitative analysis of p3-Alcα with a new ELISA system. Mol2011

    • Author(s)
      Konno T, Hata S, Hamada Y, Horikoshi-Sakuraba Y, Nakaya T, Saito Y, Yamamoto T, Yamamoto T, Maeda M, Ikeuchi T, Gandy S, Akatsu H, Suzuki T
    • Journal Title

      Neurodegener

      Volume: 6 Pages: 76-76

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590055
  • [Journal Article] Increased amyloidogenic processing of transgenic human APP in X11-like deficient mouse brain2010

    • Author(s)
      Kondo M, Shiono M, Itoh G, Takei N, Matsushima T, Maeda M, Taru H, Hata S, Yamamoto T, Saito Y, Suzuki T
    • Journal Title

      Mol. Neurodegener

      Volume: 5 Pages: 35-35

    • NAID

      120005158908

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590055
  • [Journal Article] Increased amyloidogenic processing of transgenic human APP in X11-like deficient mouse brain.2010

    • Author(s)
      Kondo M, Shiono M, Itoh G, Takei N, Matsushima T, Maeda M, Taru H, Hata S, Yamamoto T , Saito Y, Suzuki T.
    • Journal Title

      Mol. Neurodegener. 5

      Pages: 35-35

    • NAID

      120005158908

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20200011
  • [Journal Article] Phosphorylation of the amino-terminal region of X11L regulates its interaction with APP.2009

    • Author(s)
      Sakuma M, Tanaka E, Taru H, Tomita S, Gandy S, Narin AC, Nakaya T, Yamamoto T, Suzuki T.
    • Journal Title

      J.Neurochem. 109

      Pages: 465-475

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20200011
  • [Journal Article] Suppression of APP-containing vesicle trafficking and production of beta-amyloid by AID/DHHC12 protein.2009

    • Author(s)
      Mizumaru C, Saito Y, Ishikawa T, Yoshida T, Yamamoto T, Nakaya T, Suzuki T.
    • Journal Title

      J.Neurochem. 111

      Pages: 1213-1224

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20200011
  • [Journal Article] Paths, elongation, and projections of ascending chick embryonic spinal commissural neurons after crossing the floor plate.2008

    • Author(s)
      Arakawa T, Iwashita M, Matsuzaki F, Suzuki T, Yamamoto T.
    • Journal Title

      Brain Res. 1223

      Pages: 25-33

    • NAID

      120000947313

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20200011
  • [Journal Article] The X11L/X11beta/MINT2 and X11L2/X11gamma/MINT3 scaffold proteins shuttle between the nucleus and cytoplasm.2008

    • Author(s)
      Sumioka A, Saito Y, Sakuma M, Araki Y, Yamamoto T, Suzuki T.
    • Journal Title

      Exp.Cell Res. 314

      Pages: 1155-1162

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20200011
  • [Journal Article] X11 proteins regulate the translocation of amyloid beta-protein precursor (APP) into detergent-resistant membrane and suppress the amyloidogenic cleavage of APP by beta-site-cleaving enzyme in brain.2008

    • Author(s)
      Saito Y, Sano Y, Vassar R, Gandy S, Nakaya T, Yamamoto T, Suzuki T.
    • Journal Title

      J. Biol.Chem. 283

      Pages: 35763-35771

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20200011
  • [Patent] パーキンソン病の診断指標2019

    • Inventor(s)
      山本 融 他
    • Industrial Property Rights Holder
      香川大学 他
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2019-033661
    • Filing Date
      2019
    • Data Source
      KAKENHI-PROJECT-16K08237
  • [Presentation] シナプス形成抑制因子MDGA1/2の欠失による対蹠的なE/Iバランス・行動異常と、これを抑止する薬剤の探索2023

    • Author(s)
      山本 融、尾嶋 大喜、多田 篤史、窪田 剛志、髙橋 弘雄、冨永 貴志、岸本 泰司
    • Organizer
      日本薬学会 第143年会
    • Data Source
      KAKENHI-PROJECT-22K06597
  • [Presentation] シナプス形成抑制因子MDGA1/2の欠失による対蹠的なE/Iバランス・行動異常と、これを抑止する薬剤の探索2023

    • Author(s)
      山本 融、尾嶋 大喜、多田 篤史、窪田 剛志、髙橋 弘雄、冨永 貴志、岸本 泰司
    • Organizer
      日本薬学会 第143年会
    • Data Source
      KAKENHI-PROJECT-19K07065
  • [Presentation] シナプス形成抑制因子MDGA1/2の欠失がもたらす対蹠的な興奮/抑制バランス偏移と行動異常は成年期の薬剤投与で回復する2023

    • Author(s)
      山本 融、尾嶋 大喜、多田 篤史、窪田 剛志、髙橋 弘雄、冨永 貴志、岸本 泰司
    • Organizer
      第46回分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-19K07065
  • [Presentation] シナプス形成抑制因子MDGA1/2の欠失がもたらす対蹠的な興奮/抑制バランス偏移と行動異常は成年期の薬剤投与で回復する2023

    • Author(s)
      山本 融、尾嶋 大喜、多田 篤史、窪田 剛志、髙橋 弘雄、冨永 貴志、岸本 泰司
    • Organizer
      第46回分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-22K06597
  • [Presentation] 脳梗塞に対する時間依存的神経保護メカニズム2023

    • Author(s)
      高橋 弘雄、尾嶋 大喜、多田 篤史、坪井 昭夫、山本 融
    • Organizer
      第46回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-19K07065
  • [Presentation] 脳梗塞に対する時間依存的神経保護メカニズム2023

    • Author(s)
      高橋 弘雄、尾嶋 大喜、多田 篤史、坪井 昭夫、山本 融
    • Organizer
      日本薬学会 第143年会
    • Data Source
      KAKENHI-PROJECT-19K07065
  • [Presentation] 脳梗塞に対する時間依存的神経保護メカニズム2023

    • Author(s)
      高橋 弘雄、尾嶋 大喜、多田 篤史、坪井 昭夫、山本 融
    • Organizer
      第46回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-22K06597
  • [Presentation] 脳虚血に対する時間依存的な神経保護メカニズム2022

    • Author(s)
      高橋 弘雄、尾嶋 大喜、坪井 昭夫、山本 融
    • Organizer
      第45回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-19K07065
  • [Presentation] 脳虚血に対する時間依存的な神経保護メカニズム2022

    • Author(s)
      高橋 弘雄、尾嶋 大喜、坪井 昭夫、山本 融
    • Organizer
      第45回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-22K06597
  • [Presentation] シナプス形成抑制因子MDGA1/2の欠失は対蹠的な興奮/抑制バランス偏移と行動異常を引き起こすが、成年期の薬剤投与により回復できる2022

    • Author(s)
      山本 融、尾嶋 大喜、多田 篤史、窪田 剛志、髙橋 弘雄、冨永 貴志、岸本 泰司
    • Organizer
      第45回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-22K06597
  • [Presentation] シナプス形成抑制因子MDGA1/2の欠失は対蹠的な興奮/抑制バランス偏移と行動異常を引き起こすが、成年期の薬剤投与により回復できる2022

    • Author(s)
      山本 融、尾嶋 大喜、多田 篤史、窪田 剛志、髙橋 弘雄、冨永 貴志、岸本 泰司
    • Organizer
      第45回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-19K07065
  • [Presentation] 抑制性シナプス抑制因子MDGA1のヘミ欠損は海馬LTPの低下と学習・記憶異常を引き起こすが、サイクロセリンの急性投与により回復する2021

    • Author(s)
      山本 融, 尾嶋 大喜, 多田 篤史, 田之上 優, 黒川 直弘, 窪田 剛志, 高橋 弘雄,岸本 泰司, 冨永 貴志
    • Organizer
      第44回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-19K07065
  • [Presentation] 転写因子Npas4による低分子量Gタンパク質Gemの発現誘導は神経活動依存的な虚血耐性を引き起こす2021

    • Author(s)
      高橋 弘雄, 松井 健, 森 英一朗, 山本 融, 坪井 昭夫
    • Organizer
      第44回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-19K07065
  • [Presentation] MDGA1ノックアウトマウスの社会性行動に対するD-サイクロセリンの効果2021

    • Author(s)
      松崎 真也、萩 かれん、中澤 鈴菜、尾嶋 大喜、山本 融、窪田 剛志、岸本 泰司
    • Organizer
      日本薬学会第141年会
    • Data Source
      KAKENHI-PROJECT-19K07065
  • [Presentation] パーキンソン病の新規バイオマーカーとしての血中p3-Alcadeinαに関する検討2021

    • Author(s)
      國土曜平, 高田忠幸, 高橋弘雄, 羽田沙緒里, 鎌田正紀, 出口一志, 峠哲男, 正木勉, 鈴木利治, 山本融
    • Organizer
      第62回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-19K07065
  • [Presentation] シナプス形成抑制因子MDGA1の欠失による精神神経疾患様行動異常と、これを抑止する薬剤の探索2020

    • Author(s)
      多田 篤史, 田之上 優,黒川 直弘,窪田 剛志,津島 希海,尾嶋 大喜,Razib Hossain,高橋 弘雄, 岸本 泰司, 山本 融
    • Organizer
      日本薬学会第140年会
    • Data Source
      KAKENHI-PROJECT-19K07065
  • [Presentation] シナプス形成抑制因子MDGA1の欠失による精神神経疾患様行動異常と、これを抑止する薬剤の探索2020

    • Author(s)
      多田 篤史, 田之上 優,黒川 直弘,窪田 剛志,津島 希海,尾嶋 大喜,Razib Hossain,高橋 弘雄, 岸本 泰司, 山本 融
    • Organizer
      日本薬学会第140年会
    • Data Source
      KAKENHI-PROJECT-16K08237
  • [Presentation] MDGA1の欠失による抑制性シナプスの過剰形成は統合失調症様の認知・行動異常をもたらす2020

    • Author(s)
      山本 融, 尾嶋 大喜, 多田 篤史, 田之上 優, 黒川 直弘, 津島 希海, Md. Razib Hossain, 窪田 剛志, 高橋 弘雄, 岸本 泰司
    • Organizer
      第43回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-19K07065
  • [Presentation] マウスプラセボ鎮痛条件づけを用いたプラセボ応答の分子基盤の探索2020

    • Author(s)
      岸本 泰司, 中村 裕子, 新開 崇広, 青野 仁美, 藤原 友佳, 大畑 南美, 松崎 真也, 山本 融
    • Organizer
      第43回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-19K07065
  • [Presentation] 転写因子Npas4による低分子量Gタンパク質Gemの発現誘導は神経活動依存的な虚血耐性を引き起こす2020

    • Author(s)
      高橋 弘雄、松井 健、森 英一朗、山本 融、坪井 昭夫
    • Organizer
      第43回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-19K07065
  • [Presentation] Enhanced β- and β’-cleavages of APP in Alcadein α knockout mouse brain.2019

    • Author(s)
      Toshiharu Suzuki, Naoya Goto, Haruka Saito, Saori Hata, Tohru Yamamoto
    • Organizer
      Alzheimer's Association International Conference 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08237
  • [Presentation] Enhanced β- and β’-cleavages of APP in Alcadein α knockout mouse brain.2019

    • Author(s)
      Toshiharu Suzuki, Naoya Goto, Haruka Saito, Saori Hata, Tohru Yamamoto
    • Organizer
      Alzheimer's Association International Conference 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07065
  • [Presentation] マウスモデルを用いたプラセボおよびノセボ反応条件づけの開発と評価2019

    • Author(s)
      青野 仁美, 藤原 友佳, 尾嶋 大喜, 山本 融, 岸本泰司
    • Organizer
      日本薬学会第139年会
    • Data Source
      KAKENHI-PROJECT-16K08237
  • [Presentation] キネシン-1によるFrizzledの軸索輸送が神経終末のWntシグナルを制御する2019

    • Author(s)
      満間 百音、白木 柚葉、齊藤 遥、高田 律子、山本 融、高田 慎治、羽田 沙緒里、鈴木 利治
    • Organizer
      第92回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-19K07065
  • [Presentation] キネシン-1によるFrizzledの軸索輸送が神経終末のWntシグナルを制御する2019

    • Author(s)
      満間 百音、白木 柚葉、齊藤 遥、高田 律子、山本 融、高田 慎治、羽田 沙緒里、鈴木 利治
    • Organizer
      第92回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-16K08237
  • [Presentation] シナプス形成抑制因子MDGAファミリー分子群の欠失が引き起こすE/Iバランス偏移がもたらす認知・行動異常2019

    • Author(s)
      山本 融,尾嶋 大喜,Razib Hossain,多田 篤史, 黒川 直弘, 長澤 研, 琢磨 和晃, 中井 雄規,高橋 弘雄, 冨永 貴志,岸本 泰司
    • Organizer
      第42回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-19K07065
  • [Presentation] シナプス形成抑制因子MDGAファミリー分子群の欠失が引き起こすE/Iバランス偏移がもたらす認知・行動異常2019

    • Author(s)
      山本 融,尾嶋 大喜,Razib Hossain,多田 篤史, 黒川 直弘, 長澤 研, 琢磨 和晃, 中井 雄規,高橋 弘雄, 冨永 貴志,岸本 泰司
    • Organizer
      第42回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-16K08237
  • [Presentation] MDGAファミリー分子群の欠失が引き起こすE/I バランス偏移に伴う認知・行動異常の解析2019

    • Author(s)
      Razib Hossain, 多田 篤史, 黒川 直弘, 長澤 研, 琢磨 和晃, 尾嶋 大喜, 高橋 弘雄, 岸本泰司, 山本 融
    • Organizer
      日本薬学会第139年会
    • Data Source
      KAKENHI-PROJECT-16K08237
  • [Presentation] Alcadein α欠損マウスにおけるAPPのアミロイド生成的代謝の促進機構2019

    • Author(s)
      鈴木 利治、後藤 直也、林 理沙、羽田 沙緒里、山本 融
    • Organizer
      第38回日本認知症学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K07065
  • [Presentation] 神経活動依存的な転写因子Npas4は脳梗塞に伴う細胞死を抑制する2019

    • Author(s)
      高橋 弘雄,朝比奈 諒,山本 融,坪井 昭夫
    • Organizer
      第42回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-19K07065
  • [Presentation] 神経活動依存的な転写因子Npas4は脳梗塞に伴う細胞死を抑制する2019

    • Author(s)
      高橋 弘雄,朝比奈 諒,山本 融,坪井 昭夫
    • Organizer
      第42回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-16K08237
  • [Presentation] Alcadein α欠損マウスにおけるAPPのアミロイド生成的代謝の促進機構2019

    • Author(s)
      鈴木 利治、後藤 直也、林 理沙、羽田 沙緒里、山本 融
    • Organizer
      第38回日本認知症学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K08237
  • [Presentation] Alcadein αノックアウトマウスは加齢で網膜神経節細胞が脱落する2018

    • Author(s)
      中野裕貴 小野葵 小林守 高砂縁 村山千明 尾嶋大喜 山本融 廣岡一行
    • Organizer
      第122回 日本眼科学会総会
    • Data Source
      KAKENHI-PROJECT-16K08237
  • [Presentation] Retinal Ganglion Cell Loss in Alcadeinα Knockout Mice.2018

    • Author(s)
      Yuki Nakano, Aoi Ono, Mamoru Kobayashi, Yukari Takasago, Chiaki Murakami, Daiki Ozima, Tohru Yamamoto, Kazuyuki Hirooka
    • Organizer
      ARVO 2018: The Association for Research in Vision and Ophthalmology Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08237
  • [Presentation] Synaptopathies associated with loss of MDGAs.2018

    • Author(s)
      Steven Connor, Ina Ammendrup-Johnsen, Yasushi Kishimoto, Parisa Karimi Tari, Vedrana Cvetkovska, Takashi Harada, Daiki Ojima, Tohru Yamamoto, Yu Tian Wang, Ann Marie Craig
    • Organizer
      17th Annual Molecular and Cellular Cognition Society Meeting.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08237
  • [Presentation] MDGA1は抑制性シナプス形成抑制因子であり、その欠損は興奮性の抑制と学習・記憶能力の障害をもたらす2018

    • Author(s)
      山本 融 Steven A. Connor 岸本 泰司 Ina Ammendrup-Johnsen 原田 岳 尾嶋 大喜 Razib Hossain  Ann Marie Craig
    • Organizer
      日本薬学会第138年会
    • Data Source
      KAKENHI-PROJECT-16K08237
  • [Presentation] シナプス形成抑制因子MDGA1の欠損は興奮/抑制バランスの抑制側へのシフトによる学習・記憶障害をもたらす2018

    • Author(s)
      山本 融 Steven A. Connor  Ina Ammendrup-Johnsen 岸本 泰司 原田 岳 尾嶋 大喜 Razib Hossain Ann Marie Craig
    • Organizer
      第41回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-16K08237
  • [Presentation] シナプス形成抑制因子MDGA2のヘミ欠損は興奮/抑制バランスの興奮側へのシフトによるASD様の社会性行動異常をもたらす2017

    • Author(s)
      山本 融 Steven A. Connor 岸本 泰司 Ina Ammendrup-Johnsen 栗原 直和 村山 千明 尾嶋 大喜 Razib Hossain 鈴木 利治 Ann Marie Craig
    • Organizer
      第40回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-16K08237
  • [Presentation] MDGA2は興奮性シナプス形成抑制因子であり、そのヘミ欠損は興奮性の亢進とASD様の行動異常をもたらす2017

    • Author(s)
      山本 融 Steven A. Connor 岸本 泰司 Ina Ammendrup-Johnsen 栗原 直和 村山 千明 尾嶋 大喜 Razib Hossain 鈴木 利治 Ann Marie Craig
    • Organizer
      日本薬学会第137年
    • Place of Presentation
      仙台国際センター・東北大学
    • Year and Date
      2017-03-24
    • Data Source
      KAKENHI-PROJECT-16K08237
  • [Presentation] Haploinsufficiency of the neuronal surface protein MDGA2 enhances excitatory synapse development, alters cortical circuit dynamics and yields behavioral phenotypes consistent with autism in mice.2016

    • Author(s)
      Connor SA, Ammendrup-Johnsen I, Chan AW, Kishimoto Y, Murayama C, Ojima D, Kurihara N, Tada A, Ge Y, Lu H, Yan R, LeDue JM, Matsumoto H, Kiyonari H, Kirino Y, Matsuzaki F, Suzuki T, Murphy TH, Wang YT, Yamamoto T, Craig AM.
    • Organizer
      Society for Neuroscience annual meeting
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2016-11-12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08237
  • [Presentation] シナプス形成抑制因子MDGA2のヘミ欠失マウスは興奮性入力の亢進によりもたらされる自閉症スペクトラム障害のモデルとなる2016

    • Author(s)
      山本 融 Steven A. Connor 岸本 泰司 Ina Ammendrup-Johnsen 栗原 直和 村山 千明 鈴木 利治 Ann Marie Craig
    • Organizer
      第39回分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2016-11-30
    • Data Source
      KAKENHI-PROJECT-16K08237
  • [Presentation] Absence of MDGA1 Enhances Inhibitory Drive and Confers Resistance to Increased Excitation in Mouse Hippocampus2015

    • Author(s)
      Steven A. Connor, Ina Ammendrup-Johnsen, Parisa Karimi Tari, Tohru Yamamoto, Yu Tian Wang, and Ann Marie Craig
    • Organizer
      9th Annual Canadian Neuroscience Meeting
    • Place of Presentation
      Westin Bayshore, Vancouver, Canada
    • Year and Date
      2015-05-24
    • Data Source
      KAKENHI-PROJECT-25460059
  • [Presentation] アルカデインはX11Lと協働して内在性APPのアミロイド産生的代謝を抑制する2015

    • Author(s)
      山本 融 後藤 直也 齋藤 有紀 村山 千明 鈴木 利治
    • Organizer
      第38回分子生物学会年会・第88回日本生化学会大会 合同大会
    • Place of Presentation
      神戸国際会議場
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-25460059
  • [Presentation] JIP1を介したAPP軸索順行輸送の制御機構解析2015

    • Author(s)
      加藤 優実 千葉 杏子 山本 融 鈴木 利治
    • Organizer
      第38回分子生物学会年会・第88回日本生化学会大会 合同大会
    • Place of Presentation
      神戸国際会議場
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-25460059
  • [Presentation] 大脳新皮質形成時における放射状細胞移動の細胞種による多様性2015

    • Author(s)
      尾嶋 大喜 山本 融
    • Organizer
      第38回分子生物学会年会・第88回日本生化学会大会 合同大会
    • Place of Presentation
      神戸国際会議場
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-25460059
  • [Presentation] 脊髄上行性伝導路の形成機構2013

    • Author(s)
      山本 融
    • Organizer
      第118回日本解剖学会総会・全国学術集会
    • Place of Presentation
      サンポートホール高松・かがわ国際会議場(香川)
    • Invited
    • Data Source
      KAKENHI-PROJECT-22590055
  • [Presentation] 脊髄上行性伝導路の形成機構2013

    • Author(s)
      山本融
    • Organizer
      第118回日本解剖学会総会・全国学術集会
    • Place of Presentation
      サンポートホール高松・かがわ国際会議場
    • Data Source
      KAKENHI-PROJECT-22590055
  • [Presentation] Constitutive cleavage of a single pass transmembrane protein Alcadeinα prevents aberrant peripheral retention of kinesin-1.2012

    • Author(s)
      Tohru Yamamoto
    • Organizer
      Society for Neuroscience annual meeting, Neuroscience 2012
    • Place of Presentation
      Ernest N. Morial Convention Center ( USA)
    • Data Source
      KAKENHI-PROJECT-22590055
  • [Presentation] Constitutive cleavage of a single pass transmembrane protein Alcadeinα prevents aberrant peripheral retention of kinesin-12012

    • Author(s)
      Yamamoto T
    • Organizer
      Society for Neuroscience annual meeting
    • Place of Presentation
      New Orleans Ernest N. Morial Convention Center, New Orleans, USA
    • Data Source
      KAKENHI-PROJECT-22590055
  • [Presentation] Enhanced amyloidogenic p rocessing of APP in Alcadeinα-defic ient mice2011

    • Author(s)
      Yamamoto T
    • Organizer
      Society for Neuroscience annual meeting
    • Place of Presentation
      Walter E. Washington Convention Cen ter,Washington DC, USA
    • Data Source
      KAKENHI-PROJECT-22590055
  • [Presentation] Alcadeinαの欠失によりAPPのアミロイド産生的代謝は亢進する2011

    • Author(s)
      山本融
    • Organizer
      第34回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-22590055
  • [Presentation] Alcadein αの欠失によりAPPのアミロイド産生的代謝は亢進する2011

    • Author(s)
      山本融
    • Organizer
      第34回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Data Source
      KAKENHI-PROJECT-22590055
  • [Presentation] からだと脳はどのように結ばれるか-脊髄上行路形成機構の解析2011

    • Author(s)
      山本融
    • Organizer
      日本生理学会・日本解剖学会合同年会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-20200011
  • [Presentation] からだと脳はどのように結ばれるか-脊髄上行路形成機構の解析2011

    • Author(s)
      山本融
    • Organizer
      第88回日本生理学会・第116回日本解剖学会合同年会
    • Place of Presentation
      パシフィコ横浜(招待講演 誌上開催)
    • Data Source
      KAKENHI-PROJECT-20200011
  • [Presentation] WD motif : A small peptide motif is sufficient for initiating Kinesin-1 activation through part of the tetratricopeptide repeat region of KLC12011

    • Author(s)
      Yamamoto T
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Data Source
      KAKENHI-PROJECT-22590055
  • [Presentation] Enhanced amyloidogenic processing of APP in Alcadein α-deficient mice2011

    • Author(s)
      Yamamoto T
    • Organizer
      Society for Neuroscience annual meeting, Neuroscience 2011
    • Place of Presentation
      Walter E.Washington Convention Center (USA)
    • Data Source
      KAKENHI-PROJECT-22590055
  • [Presentation] からだと脳はどのように結ばれるか-脊髄上行路形成機構の解析2011

    • Author(s)
      山本融
    • Organizer
      第88回日本生理学会・第116回日本解剖学会合同年会
    • Place of Presentation
      パシフィコ横浜(誌上開催) 招待講演
    • Data Source
      KAKENHI-PROJECT-22590055
  • [Presentation] WDモチーフはキネシン1モーター活性化の開始に十分であり、その際キネシン軽鎖TPR領域のすべては必要とされない2011

    • Author(s)
      山本融
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-22590055
  • [Presentation] からだと脳はどのように結ばれるか-脊髄上行路形成機構の解析2011

    • Author(s)
      山本融
    • Organizer
      日本生理学会・日本解剖学会合同年会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-22590055
  • [Presentation] IgSF molecule MDGA1 is i nvolved in radial migration and posi tioning of a subset of cortical upper-layer neurons2010

    • Author(s)
      Yamamoto T
    • Organizer
      Society for Neurosc ience annual meeting
    • Place of Presentation
      San Diego Convention Center, San Diego USA
    • Data Source
      KAKENHI-PROJECT-22590055
  • [Presentation] Novel IgSF molecule MDGA1 is involved in radial migration and positioning of a subset of cortical upper-layer neurons.2010

    • Author(s)
      Yamamoto T
    • Organizer
      Neuro 2010
    • Place of Presentation
      神戸国際会議場
    • Data Source
      KAKENHI-PROJECT-22590055
  • [Presentation] IgSF molecule MDGA1 is in volved in radial migration and positioning of a subset of cortical upper-layer neurons2010

    • Author(s)
      Yamamoto T
    • Place of Presentation
      San Diego USA
    • Data Source
      KAKENHI-PROJECT-20200011
  • [Presentation] IaSF molecule MDGA1 is involved in radial migration and positioning of a subset of cortical upper-layer neurons.2010

    • Author(s)
      Yamamoto T
    • Organizer
      Society for Neuroscience annual meeting
    • Place of Presentation
      San Diego USA
    • Data Source
      KAKENHI-PROJECT-22590055
  • [Presentation] Novel IgSF molecule MDGA1 is involved in radial migration an d positioning of a subset of cortical upper-layer neurons2010

    • Author(s)
      Yamamoto T
    • Organizer
      Neuro 2010
    • Place of Presentation
      神戸国際会議場
    • Year and Date
      2010-09-24
    • Data Source
      KAKENHI-PROJECT-22590055
  • [Presentation] Novel IgSF molecule MDGA1 is involved in radial migration and positioning of a subset of cortical upper-layer neurons.2010

    • Author(s)
      Yamamoto T
    • Organizer
      Neuro 2010
    • Place of Presentation
      神戸国際会議場
    • Data Source
      KAKENHI-PROJECT-20200011
  • [Presentation] Novel IgSF molecule MDGA1 is involved in radial migration and positioning of a subset of cortical upper-layer neurons2010

    • Author(s)
      Yamamoto T
    • Organizer
      Neuro 2010
    • Place of Presentation
      神戸国際会議場
    • Data Source
      KAKENHI-PROJECT-20200011
  • [Presentation] IgSF molecule MDGA1 is involved in radial migration and positioning of a subset of cortical upper-layer, neurons.2010

    • Author(s)
      Yamamoto T
    • Organizer
      Society for Neuroscience annual meeting
    • Place of Presentation
      San Diego USA
    • Data Source
      KAKENHI-PROJECT-20200011
  • [Presentation] Spinocerebellar tract formation of developing chick : Paths, elongation, and projections of ascending embryonic spinal commissural neurons after crossing the floor plate.in neuronal cells and tissues2009

    • Author(s)
      Yamamoto, T
    • Organizer
      Keystone Symposia : Axonal Connections : Molecular Cues for Development and Reaeneration
    • Place of Presentation
      Keystone Resort
    • Data Source
      KAKENHI-PROJECT-20200011
  • [Presentation] Spinocerebellar tract formation of developing chick : Paths, elongation, and projections of ascending embryonic spinal commissural neurons after crossing the floor plate.2009

    • Author(s)
      Yamamoto, T
    • Organizer
      in neuronal cells and tissues, Key stone Symposia
    • Place of Presentation
      Key stone, USA
    • Data Source
      KAKENHI-PROJECT-20200011
  • [Presentation] Alcadein drives kinesin-1 and undergoes constitutive limited proteolysis to maintain proper distribution of kineisn-1.

    • Author(s)
      山本融 豊島哲彦 丸田千明 荒関雅彦 鈴木利治
    • Organizer
      第37回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-09-11 – 2014-09-13
    • Data Source
      KAKENHI-PROJECT-25460059
  • [Presentation] Ameliorative effects of Yokukansan on behavioral deficits following transient forebrain ischemia in gerbils

    • Author(s)
      劉亜南 中村丈洋 豊島哲彦 山本融 板野俊文
    • Organizer
      第37回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-09-11 – 2014-09-13
    • Data Source
      KAKENHI-PROJECT-25460059
  • []

  • []

  • []

  • 1.  HORIKOSHI Masami (70242089)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 0 results
  • 2.  OBINATA Masuo (10099971)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  SHOJI Wataru (40250831)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  葛原 隆 (00260513)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  矢内 信昭 (80200525)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  HASHIDA Ryouichi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  Craig Ann Marie
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 8.  HATA Saori
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  TARU Hidenori
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  HIMI Naoyuki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  MIYAMOTO Osamu
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  NARITA Kazuhiko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 13.  OUCHI Yasuomi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 14.  KISHIMOTO Yasushi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 15.  岡田 康志
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 16.  日置 寛之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 17.  田宮 隆
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 18.  岡部 直彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 19.  丸山 恵美
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  鈴木 利治
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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