YAMAMOTO Tohru 山本融

… Alternative Names

Researcher Number	10251480
Other IDs
External Links
Affiliation (Current)	2019: 香川大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2019: 香川大学, 医学部, 教授 2013 – 2017: 香川大学, 医学部, 教授 2012: 北海道大学, 薬学研究科(研究院), 准教授 2008 – 2012: Hokkaido University, 大学院・薬学研究院, 准教授 2003 – 2004: 独立行政法人理化学研究所, 非対称細胞分裂研究グループ, 研究員 … More
Review Section/Research Field	Principal Investigator Biological Sciences / Biological pharmacy / Molecular biology / Nerve anatomy/Neuropathology / Basic veterinary science/Basic zootechnical science / Nerve anatomy/Neuropathology / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related Except Principal Investigator Cell biology / Biological pharmacy / Biological Sciences
Keywords	Principal Investigator 神経発生 / TFIID / 神経回路 / 神経分化 / 転写因子 / 運動神経 / 新規因子 / two-hybrid法 / 転写調節 / TATAボックス結合因子 … More Except Principal Investigator 転写調節因子 / 転写調節 / 間質細胞 / two-hybrid法 / 造血幹細胞 / MysPDZ(Myo18A) / 細胞間相互作用 / 骨髄 / 遺伝子発現プロファイル / マイクロアレイ / 造血微小環境 / TFIID / 転写基本因子 / co-factor / 転写活性化 / CTD / MysPDZ / 不死化細胞株 / サイトカイン / bone marrow / gene expression profiles / 間質細胞株 / 可塑性 / STAT5 / two-hybrid system / STAT1 / Transcriptional regulation / 転写因子間相互作用 / Interaction between DNA and transcription factors / ephrinB2 / microarray / DNA-転写因子相互作用 / 共培養 / 微小環境 / Development of drugs / 癌遺伝子 / Transcriptional regulatory factor / 転写因子 / sphingoshine-1 phosphate / 幹細胞 / 多能性造血幹細胞 / 間葉系幹細胞 / Myo18A / hematopoietic-microenvironment / TATAボックス結合因子 / 相互作用 / 骨髄間質細胞 / mesenchymal stem cell cell lines / 医薬品開発 / tenascin-c / TBP / 新規ミオシン遺伝子 / コファクター / Interaction between transcription factors / TFIIB / 間葉系肝細胞 / Transcription factor Less

神経回路の新しい興奮性/抑制性バランス制御機構に着目した精神神経疾患治療薬の探索Principal InvestigatorOngoing
- Principal Investigator
  
  山本融
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Kagawa University
ＭＤＧＡファミリー分子群による興奮性/抑制性シナプス形成と社会性行動の制御Principal InvestigatorOngoing
- Principal Investigator
  
  山本融
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kagawa University
Functional analysis of MDGA family proteins on neural circuit formation of cerebral cortex.Principal Investigator
- Principal Investigator
  
  Yamamoto Tohru
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kagawa University
Functional analysis of MDGA family proteins on corticogenesis.Principal Investigator
- Principal Investigator
  
  YAMAMOTO Tohru
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
Ascending spinal tract formation in developing chickPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Tohru
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research a proposed research project)
- Research Field
  
  Nerve anatomy/Neuropathology
  Basic veterinary science/Basic zootechnical science
- Research Institution
  Hokkaido University
運動神経の特定機能単位選択的に働く新規遺伝子群の解析Principal Investigator
- Principal Investigator
  
  山本融
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research
運動神経の特定機能単位選択的に働く新規遺伝子群の解析Principal Investigator
- Principal Investigator
  
  山本融
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research
運動神経の特定機能単位選択的に働く新規遺伝子群の解析Principal Investigator
- Principal Investigator
  
  山本融
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
新規遺伝子群による運動神経回路網形成機構の解析Principal Investigator
- Principal Investigator
  
  山本融
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  The Institute of Physical and Chemical Research
  Tohoku University
Studies on Cellular Regulation of Hematopoietic Microembironment
- Principal Investigator
  
  OBINATA Masuo
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cell biology
- Research Institution
  Tohoku University
運動神経分化の過程で機能単位選択的に働く遺伝子群の探索と解析Principal Investigator
- Principal Investigator
  
  山本融
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
運動神経の軸索伸長経路の決定に関与する因子群の探索と解析Principal Investigator
- Principal Investigator
  
  山本融
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Tohoku University
造血微小環境による造血幹細胞の分化制御機構
- Principal Investigator
  
  OBINATA Masuo
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
HIV転写調節因子と相互作用する新規因子群の解析Principal Investigator
- Principal Investigator
  
  山本融
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
HIV転写調節因子と相互作用する新規因子群の検索Principal Investigator
- Principal Investigator
  
  山本融
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
ブロモドメインと相互作用する新規グローバル転写活性化因子の解析Principal Investigator
- Principal Investigator
  
  山本融
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  The University of Tokyo
転写調節機構の解析-調節因子と基本因子との相互作用を中心とした解析-
- Principal Investigator
  
  堀越正美
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
細胞周期因子CCG1と相互作用する因子の機能解析Principal Investigator
- Principal Investigator
  
  山本融
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
TFIID内Bromodomainの相互作用因子の機能解析Principal Investigator
- Principal Investigator
  
  山本融
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  The University of Tokyo
細胞周期因子CCG1の転写因子TEIIDサブユニットとしての役割Principal Investigator
- Principal Investigator
  
  山本融
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
TFIID内Bromodomainの機能解析と相互作用因子の探索Principal Investigator
- Principal Investigator
  
  山本融
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  The University of Tokyo
Basic research for development of new type of drugs based on the mechanism of transcriptional regulation
- Principal Investigator
  
  HORIKOSHI Masami
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo

All 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 Other

All Journal Article Presentation

[Journal Article] Loss of Synapse　Repressor MDGA1 Enhances Perisomatic Inhibition, Confers Resistance to　Network Excitation, and Impairs Cognitive Function.2017
- Author(s)
  Steven A. Connor, Ina Ammendrup-Johnsen, Yasushi Kishimoto, Parisa Karimi Tari, Vedrana Cvetkovska, Takashi Harada, Daiki Ojima, Tohru Yamamoto, Yu Tian Wang, Ann Marie Craig
- Journal Title
  
  Cell Rep.
  
  Volume: 26 Pages: 3637-3645
- DOI
  10.1016/j.celrep.2017.11.109
- Open Access / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08215, KAKENHI-PROJECT-16K08237, KAKENHI-PROJECT-15K07910
[Journal Article] d-Allose Attenuates Overexpression of Inflammatory Cytokines after Cerebral Ischemia/Reperfusion Injury in Gerbil.2016
- Author(s)
  Shinohara N, Nakamura T, Abe Y, Hifumi T, Kawakita K, Shinomiya A, Tamiya T, Tokuda M, Keep RF, Yamamoto T, Kuroda Y.
- Journal Title
  
  J. Stroke Cerebrovasc. Dis.
  
  Volume: 25 Pages: 2184-2188
- DOI
  10.1016/j.jstrokecerebrovasdis.2016.01.030
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293324, KAKENHI-PROJECT-26460123, KAKENHI-PROJECT-16K08237, KAKENHI-PROJECT-16K08497
[Journal Article] Ryanodine receptors contribute to the induction of ischemic tolerance.2016
- Author(s)
  Nakamura-Maruyama E, Miyamoto O, Okabe N, Himi N, Feng L, Narita K, Keep RF, Yamamoto T, Nakamura T
- Journal Title
  
  Brain Res. Bull.
  
  Volume: 122 Pages: 45-53
- DOI
  10.1016/j.brainresbull.2016.02.018
- Acknowledgement Compliant / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09846, KAKENHI-PROJECT-25460059, KAKENHI-PROJECT-15K16382, KAKENHI-PROJECT-16K08237
[Journal Article] Altered Cortical Dynamics and Cognitive Function upon Haploinsufficiency of the Autism-Linked Excitatory Synaptic Suppressor MDGA2.2016
- Author(s)
  S. A. Connor, I. Ammendrup-Johnsen, A. W. Chan, Y. Kishimoto, C. Murayama, N. Kurihara, A. Tada, Y. Ge, H. Lu, R. Yan, J. M. LeDue, H. Matsumoto, H. Kiyonari, Y. Kirino, F. Matsuzaki, T. Suzuki, T. H. Murphy, Y. T. Wang, T. Yamamoto, A. M. Craig
- Journal Title
  
  Neuron
  
  Volume: 91 Pages: 1052-1068
- DOI
  10.1016/j.neuron.2016.08.016
- Acknowledgement Compliant / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K07910, KAKENHI-PROJECT-16K08237
[Journal Article] Cytoplasmic fragment of Alcadeinα generated by regulated intramembrane proteolysis enhances APP transport into the late-secretory pathway and facilitates APP cleavage.2015
- Author(s)
  Norio Takei, Yuriko Sobu, Ayano Kimura, Satomi Urano, Yi Piao, Yoichi Araki, Hidenori Taru, Tohru Yamamoto, Saori Hata, Tadashi Nakaya, Toshiharu Suzuki
- Journal Title
  
  J Biol Chem.
  
  Volume: 290 Pages: 987-95
- DOI
  10.1074/jbc.m114.599852
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460058, KAKENHI-PROJECT-26293010, KAKENHI-PROJECT-26870464, KAKENHI-PROJECT-15K18854, KAKENHI-PROJECT-25460059
[Journal Article] Quantitative analysis of APP axonal transport in neurons; Role of JIP1 in APP anterograde transport.2014
- Author(s)
  Chiba K, Araseki M, Nozawa K, Furukori K, Araki Y, Matsushima T, Nakaya T,Hata S, Saito Y, Uchida S, Okada Y, Nairn AC, Davis RJ, Yamamoto T, Kinjo M, Taru, H, Suzuki T.
- Journal Title
  
  Mol. Biol. Cell
  
  Volume: 25 Pages: 3569-3580
- DOI
  10.1091/mbc.e14-06-1111
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25113723, KAKENHI-PROJECT-25293046, KAKENHI-PROJECT-25460058, KAKENHI-PROJECT-25460059, KAKENHI-PUBLICLY-26115721, KAKENHI-PROJECT-26293010
[Journal Article] Increased levels of plasma p3-Alc alpha35, a major fragment of Alcadein alpha by gamma-secretase cleavage, in Alzheimer's disease2014
- Author(s)
  Omori C, Kaneko M, Nakajima E, Akatsu H, Waragai M, Maeda M, Moroshima-Kawashima M, Saito Y, Nakaya T, Taru H, Yamamoto T, Asada T, Hata S, Suzuki T. for J-ADNI
- Journal Title
  
  J. Alzheimers Dis.
  
  Volume: 39 Pages: 861-70
- DOI
  10.3233/jad-131610
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23390017, KAKENHI-PROJECT-24500431, KAKENHI-PROJECT-24500433, KAKENHI-PROJECT-24591695, KAKENHI-PROJECT-24790062, KAKENHI-PROJECT-25460058, KAKENHI-PROJECT-25460059, KAKENHI-PROJECT-26293010
[Journal Article] Mechanism of Intracellular Cleavage of Alcadeins by γ-Secretases2013
- Author(s)
  Piao Y, Kimura A, Urano S, Saito Y, Taru H, Yamamoto T, Hata S, Suzuki T
- Journal Title
  
  PLoS One
  
  Volume: 8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590055
[Journal Article] Constitutive cleavage of the single-pass transmembrane protein Alcadein α prevents aberrant peripheral retention of Kinesin-12012
- Author(s)
  Maruta C, Saito Y, Hata S, Gotoh N, Suzuki T, Yamamoto T
- Journal Title
  
  PLoS One
  
  Volume: 7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590055
[Journal Article] A small peptide sequence is sufficient for nitiating kinesin-1 activation through part of TPR region of KLC12012
- Author(s)
  Kawano T, Araseki M, Araki Y, Kinjo M, Yamamoto T, Suzuki T
- Journal Title
  
  Traffic
  
  Volume: 13 Pages: 834-848
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590055
[Journal Article] Membrane-microdomainlocalization of amyloid β -precursor protein (APP) C-terminal fragments is regulated by phosphorylation of the cytoplasmic Thr668 residue2012
- Author(s)
  Matsushima T, Saito Y, Elliott JI, Iijima-Ando K, Nishimura M, Kimura N, Hata S, Yamamoto T, Nakaya T, Suzuki T
- Journal Title
  
  J. Biol. Chem
  
  Volume: 287 Pages: 19715-19724
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590055
[Journal Article] IgSF molecule M DGA1 is involved in radial migration and positioning of a subset of cortical upper layer neurons.2011
- Author(s)
  Ishikawa T, Gotoh N, Murayama C, Abe T, Iwashita M, Matsuzaki F, Suzuki T, Yamamoto T.
- Journal Title
  
  Dev. Dyn. 240
  
  Pages: 96-107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200011
[Journal Article] Expression of sorting nexin 18 (SNX18) is dynamically regulated in developing spinal motor neurons.2011
- Author(s)
  Nakazawa S, Gotoh N, Matsumoto H, Murayama C, Suzuki T, Yamamoto T.
- Journal Title
  
  J. Histochem. Cytochem. 59
  
  Pages: 202-213
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200011
[Journal Article] Coordinated increase of γ-secretase reaction products in the plasma of some female Japanese sporadic Alzheimer's disease patients: quantitative analysis of p3-Alcα with a new ELISA system. Mol2011
- Author(s)
  Konno T, Hata S, Hamada Y, Horikoshi-Sakuraba Y, Nakaya T, Saito Y, Yamamoto T, Yamamoto T, Maeda M, Ikeuchi T, Gandy S, Akatsu H, Suzuki T
- Journal Title
  
  Neurodegener
  
  Volume: 6 Pages: 76-76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590055
[Journal Article] IgSF molecule MDGA1 is involved in radial migration and positioning of a subset of cortical upper layer neurons2011
- Author(s)
  Ishikawa T, Gotoh N, Murayama C, Abe T, Iwashita M, Matsuzaki F, Suzuki T, Yamamoto T
- Journal Title
  
  Dev. Dyn
  
  Volume: 240 Pages: 96-107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590055
[Journal Article] Intracellular trafficking of the amyloid β-protein precursor(APP)regulated by novel function of X11-like2011
- Author(s)
  Saito Y, Akiyama M, Araki Y, Sumioka A, Shiono M, Taru H, Nakaya T, Yamamoto T, Suzuki T
- Journal Title
  
  PLoS One
  
  Volume: 6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590055
[Journal Article] Expression of sorting nexin 18 (SNX18) is dynamically regulated in developing spinal motor neurons2011
- Author(s)
  Nakazawa S, Gotoh N, Matsumoto H, Murayama C, Suzuki T, Yamamoto T
- Journal Title
  
  J. Histochem. Cytochem
  
  Volume: 59 Pages: 202-213
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590055
[Journal Article] Increased amyloidogenic processing of transgenic human APP in X11-like deficient mouse brain.2010
- Author(s)
  Kondo M, Shiono M, Itoh G, Takei N, Matsushima T, Maeda M, Taru H, Hata S, Yamamoto T , Saito Y, Suzuki T.
- Journal Title
  
  Mol. Neurodegener. 5
  
  Pages: 35-35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200011
[Journal Article] Increased amyloidogenic processing of transgenic human APP in X11-like deficient mouse brain2010
- Author(s)
  Kondo M, Shiono M, Itoh G, Takei N, Matsushima T, Maeda M, Taru H, Hata S, Yamamoto T, Saito Y, Suzuki T
- Journal Title
  
  Mol. Neurodegener
  
  Volume: 5 Pages: 35-35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590055
[Journal Article] Suppression of APP-containing vesicle trafficking and production of beta-amyloid by AID/DHHC12 protein.2009
- Author(s)
  Mizumaru C, Saito Y, Ishikawa T, Yoshida T, Yamamoto T, Nakaya T, Suzuki T.
- Journal Title
  
  J.Neurochem. 111
  
  Pages: 1213-1224
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200011
[Journal Article] Phosphorylation of the amino-terminal region of X11L regulates its interaction with APP.2009
- Author(s)
  Sakuma M, Tanaka E, Taru H, Tomita S, Gandy S, Narin AC, Nakaya T, Yamamoto T, Suzuki T.
- Journal Title
  
  J.Neurochem. 109
  
  Pages: 465-475
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200011
[Journal Article] Paths, elongation, and projections of ascending chick embryonic spinal commissural neurons after crossing the floor plate.2008
- Author(s)
  Arakawa T, Iwashita M, Matsuzaki F, Suzuki T, Yamamoto T.
- Journal Title
  
  Brain Res. 1223
  
  Pages: 25-33
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200011
[Journal Article] The X11L/X11beta/MINT2 and X11L2/X11gamma/MINT3 scaffold proteins shuttle between the nucleus and cytoplasm.2008
- Author(s)
  Sumioka A, Saito Y, Sakuma M, Araki Y, Yamamoto T, Suzuki T.
- Journal Title
  
  Exp.Cell Res. 314
  
  Pages: 1155-1162
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200011
[Journal Article] X11 proteins regulate the translocation of amyloid beta-protein precursor (APP) into detergent-resistant membrane and suppress the amyloidogenic cleavage of APP by beta-site-cleaving enzyme in brain.2008
- Author(s)
  Saito Y, Sano Y, Vassar R, Gandy S, Nakaya T, Yamamoto T, Suzuki T.
- Journal Title
  
  J. Biol.Chem. 283
  
  Pages: 35763-35771
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200011
[Presentation] MDGA1は抑制性シナプス形成抑制因子であり、その欠損は興奮性の抑制と学習・記憶能力の障害をもたらす2018
- Author(s)
  山本融　Steven A. Connor　岸本泰司　Ina Ammendrup-Johnsen　原田岳　尾嶋大喜　Razib Hossain　 Ann Marie Craig
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16K08237
[Presentation] シナプス形成抑制因子ＭＤＧＡ２のヘミ欠損は興奮/抑制バランスの興奮側へのシフトによるＡＳＤ様の社会性行動異常をもたらす2017
- Author(s)
  山本融　Steven A. Connor　岸本泰司　Ina Ammendrup-Johnsen　栗原直和　村山千明　尾嶋大喜　Razib Hossain　鈴木利治　Ann Marie Craig
- Organizer
  第40回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-16K08237
[Presentation] MDGA2は興奮性シナプス形成抑制因子であり、そのヘミ欠損は興奮性の亢進とASD様の行動異常をもたらす2017
- Author(s)
  山本融　Steven A. Connor　岸本泰司　Ina Ammendrup-Johnsen　栗原直和　村山千明　尾嶋大喜　Razib Hossain　鈴木利治　Ann Marie Craig
- Organizer
  日本薬学会第137年
- Place of Presentation
  仙台国際センター・東北大学
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-16K08237
[Presentation] Haploinsufficiency of the neuronal surface protein MDGA2 enhances excitatory synapse development, alters cortical circuit dynamics and yields behavioral phenotypes consistent with autism in mice.2016
- Author(s)
  Connor SA, Ammendrup-Johnsen I, Chan AW, Kishimoto Y, Murayama C, Ojima D, Kurihara N, Tada A, Ge Y, Lu H, Yan R, LeDue JM, Matsumoto H, Kiyonari H, Kirino Y, Matsuzaki F, Suzuki T, Murphy TH, Wang YT, Yamamoto T, Craig AM.
- Organizer
  Society for Neuroscience annual meeting
- Place of Presentation
  San Diego, USA
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08237
[Presentation] シナプス形成抑制因子MDGA2のヘミ欠失マウスは興奮性入力の亢進によりもたらされる自閉症スペクトラム障害のモデルとなる2016
- Author(s)
  山本融　Steven A. Connor　岸本泰司　Ina Ammendrup-Johnsen　栗原直和　村山千明　鈴木利治　Ann Marie Craig
- Organizer
  第39回分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K08237
[Presentation] Absence of MDGA1 Enhances Inhibitory Drive and Confers Resistance to Increased Excitation in Mouse Hippocampus2015
- Author(s)
  Steven A. Connor, Ina Ammendrup-Johnsen, Parisa Karimi Tari, Tohru Yamamoto, Yu Tian Wang, and Ann Marie Craig
- Organizer
  9th Annual Canadian Neuroscience Meeting
- Place of Presentation
  Westin Bayshore, Vancouver, Canada
- Year and Date
  2015-05-24
- Data Source
  KAKENHI-PROJECT-25460059
[Presentation] アルカデインはX11Lと協働して内在性APPのアミロイド産生的代謝を抑制する2015
- Author(s)
  山本融　後藤直也　齋藤有紀　村山千明　鈴木利治
- Organizer
  第38回分子生物学会年会・第88回日本生化学会大会　合同大会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25460059
[Presentation] 大脳新皮質形成時における放射状細胞移動の細胞種による多様性2015
- Author(s)
  尾嶋大喜　山本融
- Organizer
  第38回分子生物学会年会・第88回日本生化学会大会　合同大会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25460059
[Presentation] JIP1を介したAPP軸索順行輸送の制御機構解析2015
- Author(s)
  加藤優実　千葉杏子　山本融　鈴木利治
- Organizer
  第38回分子生物学会年会・第88回日本生化学会大会　合同大会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25460059
[Presentation] 脊髄上行性伝導路の形成機構2013
- Author(s)
  山本融
- Organizer
  第118回日本解剖学会総会・全国学術集会
- Place of Presentation
  サンポートホール高松・かがわ国際会議場
- Data Source
  KAKENHI-PROJECT-22590055
[Presentation] 脊髄上行性伝導路の形成機構2013
- Author(s)
  山本融
- Organizer
  第118回日本解剖学会総会・全国学術集会
- Place of Presentation
  サンポートホール高松・かがわ国際会議場（香川）
- Invited
- Data Source
  KAKENHI-PROJECT-22590055
[Presentation] Constitutive cleavage of a single pass transmembrane protein Alcadeinα prevents aberrant peripheral retention of kinesin-12012
- Author(s)
  Yamamoto T
- Organizer
  Society for Neuroscience annual meeting
- Place of Presentation
  New Orleans Ernest N. Morial Convention Center, New Orleans, USA
- Data Source
  KAKENHI-PROJECT-22590055
[Presentation] Constitutive cleavage of a single pass transmembrane protein Alcadeinα prevents aberrant peripheral retention of kinesin-1.2012
- Author(s)
  Tohru Yamamoto
- Organizer
  Society for Neuroscience annual meeting, Neuroscience 2012
- Place of Presentation
  Ernest N. Morial Convention Center ( USA)
- Data Source
  KAKENHI-PROJECT-22590055
[Presentation] Enhanced amyloidogenic p rocessing of APP in Alcadeinα-defic ient mice2011
- Author(s)
  Yamamoto T
- Organizer
  Society for Neuroscience annual meeting
- Place of Presentation
  Walter E. Washington Convention Cen ter,Washington DC, USA
- Data Source
  KAKENHI-PROJECT-22590055
[Presentation] WD motif : A small peptide motif is sufficient for initiating Kinesin-1 activation through part of the tetratricopeptide repeat region of KLC12011
- Author(s)
  Yamamoto T
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Data Source
  KAKENHI-PROJECT-22590055
[Presentation] Enhanced amyloidogenic processing of APP in Alcadein α-deficient mice2011
- Author(s)
  Yamamoto T
- Organizer
  Society for Neuroscience annual meeting, Neuroscience 2011
- Place of Presentation
  Walter E.Washington Convention Center (USA)
- Data Source
  KAKENHI-PROJECT-22590055
[Presentation] からだと脳はどのように結ばれるか-脊髄上行路形成機構の解析2011
- Author(s)
  山本融
- Organizer
  第88回日本生理学会・第116回日本解剖学会合同年会
- Place of Presentation
  パシフィコ横浜(招待講演誌上開催)
- Data Source
  KAKENHI-PROJECT-20200011
[Presentation] Alcadeinαの欠失によりAPPのアミロイド産生的代謝は亢進する2011
- Author(s)
  山本融
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-22590055
[Presentation] からだと脳はどのように結ばれるか-脊髄上行路形成機構の解析2011
- Author(s)
  山本融
- Organizer
  第88回日本生理学会・第116回日本解剖学会合同年会
- Place of Presentation
  パシフィコ横浜(誌上開催) 招待講演
- Data Source
  KAKENHI-PROJECT-22590055
[Presentation] WDモチーフはキネシン1モーター活性化の開始に十分であり、その際キネシン軽鎖TPR領域のすべては必要とされない2011
- Author(s)
  山本融
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-22590055
[Presentation] Alcadein αの欠失によりAPPのアミロイド産生的代謝は亢進する2011
- Author(s)
  山本融
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Data Source
  KAKENHI-PROJECT-22590055
[Presentation] からだと脳はどのように結ばれるか-脊髄上行路形成機構の解析2011
- Author(s)
  山本融
- Organizer
  日本生理学会・日本解剖学会合同年会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-20200011
[Presentation] からだと脳はどのように結ばれるか-脊髄上行路形成機構の解析2011
- Author(s)
  山本融
- Organizer
  日本生理学会・日本解剖学会合同年会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-22590055
[Presentation] Novel IgSF molecule MDGA1 is involved in radial migration an d positioning of a subset of cortical upper-layer neurons2010
- Author(s)
  Yamamoto T
- Organizer
  Neuro 2010
- Place of Presentation
  神戸国際会議場
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-22590055
[Presentation] IgSF molecule MDGA1 is i nvolved in radial migration and posi tioning of a subset of cortical upper-layer neurons2010
- Author(s)
  Yamamoto T
- Organizer
  Society for Neurosc ience annual meeting
- Place of Presentation
  San Diego Convention Center, San Diego USA
- Data Source
  KAKENHI-PROJECT-22590055
[Presentation] IgSF molecule MDGA1 is involved in radial migration and positioning of a subset of cortical upper-layer, neurons.2010
- Author(s)
  Yamamoto T
- Organizer
  Society for Neuroscience annual meeting
- Place of Presentation
  San Diego USA
- Data Source
  KAKENHI-PROJECT-20200011
[Presentation] Novel IgSF molecule MDGA1 is involved in radial migration and positioning of a subset of cortical upper-layer neurons2010
- Author(s)
  Yamamoto T
- Organizer
  Neuro 2010
- Place of Presentation
  神戸国際会議場
- Data Source
  KAKENHI-PROJECT-20200011
[Presentation] IgSF molecule MDGA1 is in volved in radial migration and positioning of a subset of cortical upper-layer neurons2010
- Author(s)
  Yamamoto T
- Place of Presentation
  San Diego USA
- Data Source
  KAKENHI-PROJECT-20200011
[Presentation] IaSF molecule MDGA1 is involved in radial migration and positioning of a subset of cortical upper-layer neurons.2010
- Author(s)
  Yamamoto T
- Organizer
  Society for Neuroscience annual meeting
- Place of Presentation
  San Diego USA
- Data Source
  KAKENHI-PROJECT-22590055
[Presentation] Spinocerebellar tract formation of developing chick : Paths, elongation, and projections of ascending embryonic spinal commissural neurons after crossing the floor plate.in neuronal cells and tissues2009
- Author(s)
  Yamamoto, T
- Organizer
  Keystone Symposia : Axonal Connections : Molecular Cues for Development and Reaeneration
- Place of Presentation
  Keystone Resort
- Data Source
  KAKENHI-PROJECT-20200011
[Presentation] Spinocerebellar tract formation of developing chick : Paths, elongation, and projections of ascending embryonic spinal commissural neurons after crossing the floor plate.2009
- Author(s)
  Yamamoto, T
- Organizer
  in neuronal cells and tissues, Key stone Symposia
- Place of Presentation
  Key stone, USA
- Data Source
  KAKENHI-PROJECT-20200011
[Presentation] Ameliorative effects of Yokukansan on behavioral deficits following transient forebrain ischemia in gerbils
- Author(s)
  劉亜南　中村丈洋　豊島哲彦　山本融　板野俊文
- Organizer
  第37回日本神経科学大会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-25460059
[Presentation] Alcadein drives kinesin-1 and undergoes constitutive limited proteolysis to maintain proper distribution of kineisn-1.
- Author(s)
  山本融　豊島哲彦　丸田千明　荒関雅彦　鈴木利治
- Organizer
  第37回日本神経科学大会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-25460059

1. HORIKOSHI Masami (70242089)

# of Collaborated Projects: 9 results

# of Collaborated Products: 0 results
2. OBINATA Masuo (10099971)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. SHOJI Wataru (40250831)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 葛原隆 (00260513)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 矢内信昭 (80200525)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. HASHIDA Ryouichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. Craig Ann Marie

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. TARU Hidenori

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
9. HATA Saori

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
10. KISHIMOTO Yasushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
11. HIMI Naoyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. MIYAMOTO Osamu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. NARITA Kazuhiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. AKATSU Hiroyasu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. WARAGAI Masaaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 鈴木利治

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
17. 武井則雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 田宮隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 徳田雅明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 岡部直彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 岡田康志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 寺原陽子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 島知弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 森島真帆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

YAMAMOTO Tohru 山本 融

山本 融 ヤマモト トオル

Research Projects

Research Products

Co-Researchers

神経回路の新しい興奮性/抑制性バランス制御機構に着目した精神神経疾患治療薬の探索Principal InvestigatorOngoing

Principal Investigator

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ＭＤＧＡファミリー分子群による興奮性/抑制性シナプス形成と社会性行動の制御Principal InvestigatorOngoing

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Functional analysis of MDGA family proteins on neural circuit formation of cerebral cortex.Principal Investigator

Principal Investigator

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Functional analysis of MDGA family proteins on corticogenesis.Principal Investigator

Principal Investigator

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Ascending spinal tract formation in developing chickPrincipal Investigator

Principal Investigator

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運動神経の特定機能単位選択的に働く新規遺伝子群の解析Principal Investigator

Principal Investigator

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運動神経の特定機能単位選択的に働く新規遺伝子群の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

運動神経の特定機能単位選択的に働く新規遺伝子群の解析Principal Investigator

Principal Investigator

Project Period (FY)

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Review Section

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新規遺伝子群による運動神経回路網形成機構の解析Principal Investigator

Principal Investigator

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Research Institution

Studies on Cellular Regulation of Hematopoietic Microembironment

Principal Investigator

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運動神経分化の過程で機能単位選択的に働く遺伝子群の探索と解析Principal Investigator

Principal Investigator

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運動神経の軸索伸長経路の決定に関与する因子群の探索と解析Principal Investigator

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造血微小環境による造血幹細胞の分化制御機構

Principal Investigator

Project Period (FY)

YAMAMOTO Tohru 山本融

山本融ヤマモトトオル

[Journal Article] Loss of Synapse　Repressor MDGA1 Enhances Perisomatic Inhibition, Confers Resistance to　Network Excitation, and Impairs Cognitive Function.2017