HANAWA Hideki 塙秀樹

… Alternative Names

Researcher Number	10256977
Affiliation (based on the past Project Information) *help	2007: Nippon Medical School, Medical Department, Assistant 2003 – 2006: 日本医科大学, 医学部, 助手 1996: 日本医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Hematology / Human genetics Except Principal Investigator Biological Sciences / Pediatrics
Keywords	Principal Investigator t(4;12)(q12;p13)転座 / TEL / c-kit / パルスフィールド法 / 遺伝子治療 / 重症複合型先天性免疫不全症 / レトロウイルスベクター / HIV-1ベクター / 挿入変異 / 白血病 … More Except Principal Investigator 遺伝子治療 / ウイルスベクター / HIVベクター / 挿入変異 / 血管新生 / リンパ腫 / 多発性骨髄腫 / 膵癌 / 血管新生阻害 / エンドスタチン / アンギオスタチン / 白血病 / 非分裂細胞 / 血管新生抑制因子 / 骨髄幹細胞 / アデノウイルスベクター / エイズ / ATL / 血液脳関門 / リソゾーム病 / マンノース-6-リン酸受容体 / 異染性白質ジストロフィー / アリルスルファターゼ / マンノース6リン酸 / トランスサイトーシス / Gene therapy / Viral vector / Blood brain barrier / Lysosomal diseases / Mannose-6 phosp[hate receptor / Metachromatic leukodystrophy Less

Development of assay system to quantify insertional mutagendsis for development of safe retrovirus vectorPrincipal Investigator
- Principal Investigator
  
  HANAWA Hideki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human genetics
- Research Institution
  Nippon Medical School
Non-invasive gene therapy for inherited neurodegenerative disorders (How to cross the BBB?)
- Principal Investigator
  
  SHIMADA Takashi
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Nippon Medical School
HIVベクターの開発
- Principal Investigator
  
  SHIMADA Takashi
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nippon Medical School
t(4;12)転座白血病のTEL/X遺伝子の同定Principal Investigator
- Principal Investigator
  
  塙秀樹
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Hematology
- Research Institution
  Nippon Medical School

All 2009 2007 2006 Other

All Journal Article Presentation

[Journal Article] Leukemogenesis of b2a2-type p210 BCR/ABL in a bone marrow transplantation mouse model using a lentiviral vector2009
- Author(s)
  Uchida, N., Hanawa, H., Dan, K., Inokuchi, K., Shimada, T.
- Journal Title
  
  J Nippon Med Sch. (In press)
- NAID
  130004146984
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390305
[Journal Article] Long-term inhibition of glycosphingolipid accumulation in Fabry model mice by a single systemic injection of AAV1 vector in the neonatal period2009
- Author(s)
  Ogawa, K., Hirai, Y., Ishizaki, M., Takahashi, H., Hanawa, H., Fukunaga, Y., Shimada, T.
- Journal Title
  
  Mol.Genet.Metab. 96
  
  Pages: 91-96
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390305
[Journal Article] Optimized lentiviral vector design improves titer and transgene expression of vectors containing the chicken beta-globin locus HS4 insulator element2009
- Author(s)
  Hanawa, H., Yamamoto, M., Zhao, H., Shimada, T., Persons, DA.
- Journal Title
  
  Mol.Ther. (In press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390305
[Journal Article] Differential Characteristics of HIV-based vs.SIV-based lentiviral vector systems : gene delivery to neurons and axonal transport of expressed gene2007
- Author(s)
  Kitagawa, R., Miyachi, S., Hanawa, H., Takada, M., Shimada, T.
- Journal Title
  
  Neurosciece Res. 57
  
  Pages: 550-558
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390305
[Journal Article] Systemic Cancer Gene Therapy Using Adeno-associated Virus Type 1 Vector Expressing MDA-7/IL242007
- Author(s)
  Tahara, I., Miyake, K., Hanawa, H., Kurai, T., Hirai, Y., Ishizaki, M., Uchida, E., Tajiri, T., Shimada, T.
- Journal Title
  
  Mol Ther. 15
  
  Pages: 1805-1811
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390305
[Journal Article] Efficient Gene Transfer via Retrograde Transport in Rodent and Primate Brains by an HIV-1-Based Vector Pseudotyped with Rabies Virus Glycoprotein2007
- Author(s)
  Kato, s., Inoue, K., Kobayashi, K., Yasoshima, Y., Miyachi, S., Inoue, S., Hanawa, H., Shimada, T., Takada, M., Kobayashi, K.
- Journal Title
  
  Hum.Gene Ther. 18
  
  Pages: 1141-1151
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390305
[Journal Article] Optimized lentiviral vector design improves titer and transgene expression of vectors containing the chicken beta-globin locus HS4 insulator element.
- Author(s)
  Hanawa,H., et al.
- Journal Title
  
  Mol.Ther.In press
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390305
[Presentation] Development of leukemia/lymphoma after the long latency period in an X-SCID mouse model treated by retroviral gene therapy2007
- Author(s)
  Hanawa, H.
- Organizer
  The 13th Annual Meeting of Japan Society of Gene Therapy
- Place of Presentation
  名古屋
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590314
[Presentation] Development of leukemia/lymphoma after the long latency period in an X-SCID mouse model treated by retroviral gene the rapy2007
- Author(s)
  Hanawa, H.
- Organizer
  American Society of Gene Therapy 10th Annual Meeting
- Place of Presentation
  Seattle,USA
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590314
[Presentation] Development of leukemia/lymphoma after the long latency period in an X-SCID mouse model treated by retroviral gene therapy2007
- Author(s)
  Hanawa, H
- Organizer
  American Society of Gene Therapy 10th Annual Meeting
- Place of Presentation
  Seattle
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590314
[Presentation] Development of the insulated HIV-1 vector, which improved in both infectivity and safety2007
- Author(s)
  Hanawa, H
- Organizer
  The 52nd Annual Meeting of the Japan Society of Human Genetics
- Place of Presentation
  Tokyo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590314
[Presentation] 感染効率と安全性を両立させたインスレーターを導入したHIV-1ベクターの開発2007
- Author(s)
  塙秀樹
- Organizer
  第52回日本人類遺伝学会
- Place of Presentation
  東京
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590314
[Presentation] Development of leukemia/lymphoma after the long latency period in an X-SCID mouse model treated by retroviral gene therapy2007
- Author(s)
  Hanawa, H
- Organizer
  The 13th Annual Meeting of Japan Society of Gene Therapy
- Place of Presentation
  Nagoya
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590314
[Presentation] Development of leukemia/lymphoma after the long latency period in an X-SCID mouse model treated by retroviral gene the rapy2007
- Author(s)
  Hanawa, H.
- Organizer
  American Society of Gene Therapy 10th Annual Meeting
- Place of Presentation
  Seattle, USA
- Data Source
  KAKENHI-PROJECT-18590314
[Presentation] The MSCV-U3 Internal Promoter Strongly Activates Surrounding Cellular Promoter in Combination with Self-Inactivating (SIN)-MSCV Vector Backbone2006
- Author(s)
  Hanawa, H
- Organizer
  American Society of Gene Therapy 9th Annual Meeting
- Place of Presentation
  Baltimore
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590314
[Presentation] The MSCV-U3 Internal Promoter Strongly Activates Surrounding Cellular Promoter in Combination with Self-Inactivating(SIN)-MSCV Vector Backbone2006
- Author(s)
  Hanawa, H.
- Organizer
  American Society of Gene Therapy 9th Annual Meeting
- Place of Presentation
  Baltimore
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590314

1. SHIMADA Takashi (20125074)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
2. MIYAKE Koichi (90267211)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. MIGITA Makoto (50256963)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. WATANABE Atsushi (10307952)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. MOCHIZUKI Hideki (90230044)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 久安早苗 (00089616)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

HANAWA Hideki 塙 秀樹

塙 秀樹 ハナワ ヒデキ

Research Projects

Research Products

Co-Researchers

Development of assay system to quantify insertional mutagendsis for development of safe retrovirus vectorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Non-invasive gene therapy for inherited neurodegenerative disorders (How to cross the BBB?)

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

HIVベクターの開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

t(4;12)転座白血病のTEL/X遺伝子の同定Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Leukemogenesis of b2a2-type p210 BCR/ABL in a bone marrow transplantation mouse model using a lentiviral vector2009

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] Long-term inhibition of glycosphingolipid accumulation in Fabry model mice by a single systemic injection of AAV1 vector in the neonatal period2009

Author(s)

Journal Title

Description

Data Source

[Journal Article] Optimized lentiviral vector design improves titer and transgene expression of vectors containing the chicken beta-globin locus HS4 insulator element2009

Author(s)

Journal Title

Description

Data Source

[Journal Article] Differential Characteristics of HIV-based vs.SIV-based lentiviral vector systems : gene delivery to neurons and axonal transport of expressed gene2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Systemic Cancer Gene Therapy Using Adeno-associated Virus Type 1 Vector Expressing MDA-7/IL242007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Efficient Gene Transfer via Retrograde Transport in Rodent and Primate Brains by an HIV-1-Based Vector Pseudotyped with Rabies Virus Glycoprotein2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Optimized lentiviral vector design improves titer and transgene expression of vectors containing the chicken beta-globin locus HS4 insulator element.

Author(s)

Journal Title

Description

Data Source

[Presentation] Development of leukemia/lymphoma after the long latency period in an X-SCID mouse model treated by retroviral gene therapy2007

Author(s)

Organizer

Place of Presentation

Description

Data Source

[Presentation] Development of leukemia/lymphoma after the long latency period in an X-SCID mouse model treated by retroviral gene the rapy2007

Author(s)

Organizer

Place of Presentation

Description

Data Source

[Presentation] Development of leukemia/lymphoma after the long latency period in an X-SCID mouse model treated by retroviral gene therapy2007

Author(s)

Organizer

HANAWA Hideki 塙秀樹

塙秀樹ハナワヒデキ